Boletín médico del Hospital Infantil de México最新文献_第6页

Osteosarcoma in pre-adolescents: diagnostic interval, metastasis frequency, and treatment abandonment. 青春期前骨肉瘤：诊断间隔、转移频率和放弃治疗。

IF 0.6

Boletín médico del Hospital Infantil de México Pub Date : 2025-01-01 DOI: 10.24875/BMHIM.23000147

Ricardo Gómez-Martínez, Miguel Á Verdugo-Robles, Graciela López-Márquez, Aldo I Santiago-Aguilar, Hugo Romo-Rubio

{"title":"Osteosarcoma in pre-adolescents: diagnostic interval, metastasis frequency, and treatment abandonment.","authors":"Ricardo Gómez-Martínez, Miguel Á Verdugo-Robles, Graciela López-Márquez, Aldo I Santiago-Aguilar, Hugo Romo-Rubio","doi":"10.24875/BMHIM.23000147","DOIUrl":"https://doi.org/10.24875/BMHIM.23000147","url":null,"abstract":"Background: osteosarcoma is the most common malignant bone tumor, but it is rare before adolescence. The clinical behavior of the tumor that develops in pre-adolescents may differ from that seen during adolescence.Method: This is a retrospective study of pre-adolescents with osteosarcoma diagnosed in a tertiary-level hospital. The patients were compared with adolescents diagnosed during the same period.Results: we analyzed 149 patients (forty-four pre-adolescents). The diagnostic interval median was 7 weeks in pre-adolescents and 12 weeks in adolescents (p = 0.002). Forty-four patients had metastases at diagnosis (ten pre-adolescents) (p = 0.23). Limb-salvage surgery was performed on sixteen patients (two pre-adolescents). Fifty-six patients (thirteen pre-adolescents) abandoned the treatment (p = 0.18). Overall survival was 63 months in pre-adolescents and 52 months in adolescents (p = 0.301).Conclusion: We only found differences in the diagnostic interval, which was shorter in pre-adolescent patients. Studies with a larger number of pre-adolescents are necessary to determine the differences in the characteristics of the disease in adolescent patients.","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 3","pages":"167-171"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144706278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dengue congénito como diagnóstico diferencial en neonatos con sospecha de sepsis neonatal: reporte de caso en una región endémica. 疑似新生儿败血症的新生儿先天性登革热的鉴别诊断：流行地区的病例报告。

IF 0.5

Boletín médico del Hospital Infantil de México Pub Date : 2025-01-01 DOI: 10.24875/BMHIM.24000107

Luis A Espinoza-Venegas, Billey K Samame-Talledo, Lidia G Mauricio-Neyra, Luis Pampa-Espinoza, Fernando Munayco-Guillén, Rafael Pichardo-Rodríguez

{"title":"Dengue congénito como diagnóstico diferencial en neonatos con sospecha de sepsis neonatal: reporte de caso en una región endémica.","authors":"Luis A Espinoza-Venegas, Billey K Samame-Talledo, Lidia G Mauricio-Neyra, Luis Pampa-Espinoza, Fernando Munayco-Guillén, Rafael Pichardo-Rodríguez","doi":"10.24875/BMHIM.24000107","DOIUrl":"https://doi.org/10.24875/BMHIM.24000107","url":null,"abstract":"Background: A major dengue epidemic affected Peru in 2023, with more than 246,614 cases with 419 deaths and an approximate of 8,312 pregnant women affected, with risk of transmitting the virus to the fetus.Clinical case: The case of an 11-day-old newborn is reported, whose mother started dengue fever one day before delivery, who was admitted to the emergency room with a diagnosis of sepsis (fever, jaundice, alteration of sensorium) and a history of cesarean delivery due to acute fetal distress. RT-PCR for dengue serotype 2 was identified in both the mother and neonate, suspending antibiotics and starting controlled hydration therapy, with favorable evolution that allowed the 7 to be discharged from hospitalization.Conclusions: Congenital dengue should be suspected in any neonate whose mother presents dengue up to 10 days before delivery and who presents a clinical picture of sepsis, and we must monitor the neonate until the 12th day of life.","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 5","pages":"314-318"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145147789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of metabolic syndrome in a Chilean pediatric population with overweight and obesity. 智利儿童超重和肥胖人群中代谢综合征的患病率

IF 0.6

Boletín médico del Hospital Infantil de México Pub Date : 2025-01-01 DOI: 10.24875/BMHIM.24000127

Cesar Osorio-Fuentealba, Eduardo Cifuentes-Silva, Stefanie Arce-Pardo, Nicolas Acuña-Ordenes, Paulette Benavides-Ulloa, Camila Neira-Saldivia, Mauricio Inostroza-Mondaca

{"title":"Prevalence of metabolic syndrome in a Chilean pediatric population with overweight and obesity.","authors":"Cesar Osorio-Fuentealba, Eduardo Cifuentes-Silva, Stefanie Arce-Pardo, Nicolas Acuña-Ordenes, Paulette Benavides-Ulloa, Camila Neira-Saldivia, Mauricio Inostroza-Mondaca","doi":"10.24875/BMHIM.24000127","DOIUrl":"https://doi.org/10.24875/BMHIM.24000127","url":null,"abstract":"Background: Childhood obesity (OB) is a growing global concern, reflected in its increasing prevalence, and is one of the main causes of metabolic syndrome (MS) development. Due to the epidemiological relevance and associated complications of MS, it is necessary to conduct studies that provide local prevalence data. Our objective was to determine the prevalence of MS and the association of its components in a pediatric population with overweight (OW), obesity (OB), and severe OB (SOB).Method: This was a retrospective study. Data were collected from 122 participants, who were divided into three groups: OW, OB, and SOB. Anthropometry, lipid profile, glycemic control, and blood pressure (BP) were analyzed to assess intergroup differences and odds ratios (OR), along with a bivariate analysis.Results: The prevalence of MS was 40.1%. Triglycerides, high-density lipoprotein (HDL) cholesterol and BP showed differences between the OW and SOB groups. Fasting insulin, homeostatic model assessment (HOMA) index, systolic BP, and diastolic BP showed differences between the OW versus OB and OW versus SOB groups. Differences in ORs for MS occurrence were observed between OW versus OB (4.3), OW versus SOB (25.71), and OB versus SOB (5.7). There was an association between waist circumference, waist-to-height ratio, triglycerides, HDL cholesterol, systolic BP, fasting insulin, and HOMA index with the development of MS.Conclusion: The results of this study reveal that, locally, MS is characterized by significant differences in metabolic and anthropometric variables depending on the degree of excess weight. In addition, relevant associations were identified between specific MS components and OB severity, reinforcing the need for early diagnostic and preventive strategies in this population.","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 3","pages":"160-166"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144706280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Homenaje al Dr. Luis Velásquez Jones]. [向Luis Velasquez Jones博士致敬]。

IF 0.6

Boletín médico del Hospital Infantil de México Pub Date : 2025-01-01 DOI: 10.24875/BMHIM.M24000040

Mara Medeiros

引用次数: 0

Early developmental screening tools constructed in Latin American countries: umbrella review. 拉丁美洲国家构建的早期发育筛查工具：总括性审查。

IF 0.6

Boletín médico del Hospital Infantil de México Pub Date : 2025-01-01 DOI: 10.24875/BMHIM.24000161

Luisa Schonhaut, Antonia Valdés, Ilan Oppenheimer, Antonio Rizzoli-Córdoba, Rolando Rivera

{"title":"Early developmental screening tools constructed in Latin American countries: umbrella review.","authors":"Luisa Schonhaut, Antonia Valdés, Ilan Oppenheimer, Antonio Rizzoli-Córdoba, Rolando Rivera","doi":"10.24875/BMHIM.24000161","DOIUrl":"10.24875/BMHIM.24000161","url":null,"abstract":"Background: Multiple early childhood development (ECD) screening instruments have been developed in Latin America.Objective: The objective of this study was to describe ECD screening tests for children under 4 years of age constructed in Latin American countries in the context of healthcare, currently in use.Methods: A systematic review of literature published until April 2024 was conducted to identify screening tests constructed in Latin America. The search for each test was expanded, and individual records were completed. Authors of the instruments and/or their validations were identified and contacted to corroborate the information. An ECD screening test was defined as one that assesses at least three different domains. Only tests used in the healthcare system were included in the study. Those without publications and/or accessible information were excluded from the study.Results: Twenty-one tests constructed in nine countries (Argentina, Brazil, Chile, Colombia, Costa Rica, Cuba, Mexico, Peru, and Uruguay) were included, many used in different countries of the region. Seven were constructed and/or validated in the past 5 years. They predominantly consist of direct assessment or questions to primary caregivers. Four were validated for online use, and one for virtual use. In the validation, most combined different psychometric analyses, with heterogeneity in methodology and reference patterns. Median summary sensitivity was 0.67 (95% confidence interval [CI] 0.34-1.0), and specificity was 0.71 (95% CI 0.42-1.0).Conclusions: The ECD screening tests developed in Latin America show thorough validation and ongoing updates, though they exhibit some variability. Direct assessment using paper predominates. The consistency of the instruments, when used in different countries and populations, stands out.","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 Supl 1","pages":"5-24"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validity of administering the child development evaluation test through telemedicine to children aged 18-72 months. 远程医疗对18-72月龄儿童发展评价测验的有效性。

IF 0.6

Boletín médico del Hospital Infantil de México Pub Date : 2025-01-01 DOI: 10.24875/BMHIM.24000163

Ilma R Torres-Escobar, Miguel Á Villasis-Keever, Martha M Zapata-Tarrés, Laura A Hernández-Trejo, Christian A Delaflor-Wagner, Antonio Rizzoli-Córdoba

{"title":"Validity of administering the child development evaluation test through telemedicine to children aged 18-72 months.","authors":"Ilma R Torres-Escobar, Miguel Á Villasis-Keever, Martha M Zapata-Tarrés, Laura A Hernández-Trejo, Christian A Delaflor-Wagner, Antonio Rizzoli-Córdoba","doi":"10.24875/BMHIM.24000163","DOIUrl":"10.24875/BMHIM.24000163","url":null,"abstract":"Background: Early childhood development is a complex process that requires reliable tools for the timely detection of alterations that may affect a child's progress. The Child Development Evaluation test (EDI, in its Spanish acronym) is a screening test developed and validated in Mexico to be administered in person by a professional. The objective is to evaluate the validity of administering the EDI test through telemedicine in terms of its diagnostic concordance with the face-to-face modality.Methods: This analytical, prospective, and cross-sectional study included patients aged 18-72 months and was conducted at a tertiary care hospital in Mexico City. The test was administered through telemedicine and subsequently in person. In addition, sensitivity and specificity data were reported with confidence interval of 95% (95% CI). The face-to-face evaluator was blinded to the telemedicine results.Results: Fifty children with a median age of 47 months participated in the study. A sensitivity of 100% (95% CI, 91-100) and specificity of 100% (95% CI, 70-100) overall were obtained. Language was the higher area with a sensitivity of 100 (95% CI: 91-100) and specificity of 90 (59-98); the results for the other areas are shown. The lowest sensitivity was neurological examination (67; CI 95%: 30-90) but has the highest specificity (98; CI 95%: 88-99).Conclusion: The EDI test implemented through telemedicine shows high correlation with the face-to-face modality, maintaining high sensitivity and specificity. These results make it an appropriate method for screening children of this age, although further larger studies are needed to corroborate it.","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 Supl 1","pages":"52-58"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pediatric eosinophilic esophagitis: survey of gastroenterologists from Latin America and Spain. 小儿嗜酸性粒细胞性食管炎：来自拉丁美洲和西班牙胃肠病学家的调查。

IF 0.6

Boletín médico del Hospital Infantil de México Pub Date : 2025-01-01 DOI: 10.24875/BMHIM.24000110

María Florencia-Verdi, Gustavo Tagliaferro, Ma Alejandra Mortarini, Lorena Menendez, Andreina Guisande, Ana K Coronado-Pérez, Anabella Zosi, Felipe de J Alvarez-Chávez, Jôbert K Da Silva-Neves, Carlos J Ruiz-Hernandez

{"title":"Pediatric eosinophilic esophagitis: survey of gastroenterologists from Latin America and Spain.","authors":"María Florencia-Verdi, Gustavo Tagliaferro, Ma Alejandra Mortarini, Lorena Menendez, Andreina Guisande, Ana K Coronado-Pérez, Anabella Zosi, Felipe de J Alvarez-Chávez, Jôbert K Da Silva-Neves, Carlos J Ruiz-Hernandez","doi":"10.24875/BMHIM.24000110","DOIUrl":"10.24875/BMHIM.24000110","url":null,"abstract":"Background: Eosinophilic esophagitis (EoE) is an immuno-allergic disease characterized by esophageal dysfunction and eosinophilic infiltration of the esophagus. Its prevalence has increased, making it the leading cause of dysphagia and food impaction in children and adolescents. Understanding the approach taken by pediatric gastroenterologists in different regions is crucial.Method: Multicenter and cross-sectional observational study, carried out through a virtual questionnaire during 2022, answered voluntarily and anonymously. Percentage descriptive statistics were performed.Results: 118 responses were obtained. Approximately 3% of physicians diagnose up to two cases of eosinophilic esophagitis per year. About 55.9% performed 3-4 biopsies in the upper and lower thirds of the esophagus for diagnosis. Initial treatments in patients without stenosis: proton pump inhibitors (PPI) 33.9%, triple therapy (TT) (PPI + diet + topical corticosteroids [TCSs]) 26.27%, and combined (diet + PPI) 21%. Patients with stenosis: TT 52.58%, combined (TCSs + PPI) 13.4%. Initial dietary treatment: according to allergy tests 26.2%, empirical exclusion of 6-8 foods 25.4%, and 2-4 foods 23.7%. The first endoscopic control is performed at 8 and 12 weeks in 46.6% and 38%, respectively. 52% referred to an allergist and 47.4% to nutrition. About 48.3% do not monitor basal cortisol in corticosteroid treatment for more than 3 months.Conclusion: The diagnostic and therapeutic approach in EoE is heterogeneous. Dietary treatment shows the exclusion of a large number of foods and monitoring the prolonged use of corticosteroids is not a common practice.","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 2","pages":"121-128"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Síndrome de médula anclada en pediatría. Presentación clínica, diagnóstico, etiología y resultados del tratamiento médico-quirúrgico. 骨髓锚定综合征在儿科。临床表现、诊断、病因和医疗-外科治疗结果。

IF 0.5

Boletín médico del Hospital Infantil de México Pub Date : 2025-01-01 DOI: 10.24875/BMHIM.25000011

Antonio Heredia-Gutiérrez, María E Carbarín-Carbarín, Víctor R Ortiz-Juárez

{"title":"Síndrome de médula anclada en pediatría. Presentación clínica, diagnóstico, etiología y resultados del tratamiento médico-quirúrgico.","authors":"Antonio Heredia-Gutiérrez, María E Carbarín-Carbarín, Víctor R Ortiz-Juárez","doi":"10.24875/BMHIM.25000011","DOIUrl":"https://doi.org/10.24875/BMHIM.25000011","url":null,"abstract":"Background: Tethered cord syndrome (TCS) is the clinical manifestation of abnormal traction of the spinal cord, causing sensory-motor impairment of the lower limbs, scoliosis, low back pain, bladder and intestinal dysfunction; cutaneous abnormalities may be present. The diagnosis is suspected through clinical history and detailed physical examination. It is complemented by ultrasound and lumbosacral magnetic resonance imaging.Methods: A retrospective study was carried out from April 2019 to October 2024. The inclusion criteria: a) Under 17 years old; b)symptoms and physical examination compatible with TCS; c) imaging diagnosis of TCS, and d) having undergone surgery. The results are reported at 12 months after surgery.Results: Eighteen patients were evaluated, with an average age of 83.27 months (2-180). The etiology was hypertrophic filum (n = 6), dermal sinus (n = 4), lipomyelomeningocele (n = 4), lipomatosus filum (n = 2), and postoperative myelomeningocele (n = 2). The preoperative symptoms were bladder dysfunction 33.33%, constipation 33.33%, paraplegia 22.22%, paresthesia 22.22%, low back pain 22.22%, claw toes 16.66%, fever 16.66%, cerebrospinal fluid leakage 5.55%, club foot 5.55%, scoliosis 5.55%, and acute abdominal pain 5.55%. There were cutaneous stigmata in 61.11%. Magnetic resonance imaging was used in 17 patients and ultrasound in two. With surgery there was improvement in preoperative symptoms, the Wilcoxon test gave us a p < 0.001.Conclusions: Surgery helps to reduce symptoms and prevent further neurological damage; in asymptomatic patients it prevents the risk of neurological injury.","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 5","pages":"295-303"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145147805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Teenager with persistent facial edema and induration. 面部持续水肿和凹陷的青少年。

IF 0.6

Boletín médico del Hospital Infantil de México Pub Date : 2024-01-01 DOI: 10.24875/BMHIM.24000052

Mónica Dávalos-Tanaka, Ma Teresa García-Romero

{"title":"Teenager with persistent facial edema and induration.","authors":"Mónica Dávalos-Tanaka, Ma Teresa García-Romero","doi":"10.24875/BMHIM.24000052","DOIUrl":"10.24875/BMHIM.24000052","url":null,"abstract":"Introduction: Acute lymphoblastic leukemia (ALL) is the most common oncological disease in the pediatric population; however, skin infiltration occurs only in 1-3% of the patients and almost always manifests after the diagnosis is made.Clinical case: A male teenage patient who presented with facial edema and infiltration, associated with systemic symptoms such as asthenia and adynamia. On physical examination, the patient presented facial edema and indurated plaques, as well as cervical, inguinal, and axillary adenopathy. Complete blood count showed pancytopenia and a chest X-ray revealed a mediastinal mass. Due to a high suspicion of malignancy a bone marrow and skin biopsy was taken, both with pre-B ALL. Chemotherapy was started and the patient is now in maintenance phase.Conclusions: Leukemia cutis manifestations are heterogenous, from a small papule to a big nodule. It is more common in patients with acute myeloid leukemia and it is rare in patients with pre-B ALL, specially in the pediatric population. The diagnosis should be done with a biopsy and the treatment is with systemic chemotherapy. The diagnosis should always be considered in patients with unexplained edematous or indurated lesions, especially in the context of systemic symptoms.","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"81 5","pages":"301-304"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142387827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intramuscular vascular malformations in pediatric patients: a retrospective study in a vascular anomalies clinic. 小儿肌内血管畸形：血管畸形诊所的回顾性研究。

IF 0.6

Boletín médico del Hospital Infantil de México Pub Date : 2024-01-01 DOI: 10.24875/BMHIM.23000154

Andrea Gallardo-Villamil, Anahí Pérez-Quispe, Adolfo E Lizardo-Rodríguez, María T García Romero, Carola Durán-McKinster

{"title":"Intramuscular vascular malformations in pediatric patients: a retrospective study in a vascular anomalies clinic.","authors":"Andrea Gallardo-Villamil, Anahí Pérez-Quispe, Adolfo E Lizardo-Rodríguez, María T García Romero, Carola Durán-McKinster","doi":"10.24875/BMHIM.23000154","DOIUrl":"10.24875/BMHIM.23000154","url":null,"abstract":"Background: Intramuscular vascular malformations (IVMs) are rare developmental congenital structural abnormalities. Their clinical diagnosis is difficult, and imaging studies are essential to determine the type and extent of vessels involved. Treatment can be challenging and must be managed by a multidisciplinary team.Methods: A descriptive, observational, retrospective, longitudinal study of clinical records of patients diagnosed with IVMs who were evaluated at the vascular anomalies clinic from January 2011 to December 2021 was performed. Demographic, clinical, imaging, diagnosis, treatment, and response data were collected.Results: Seven patients (five females and two males) with a mean age of 13.66 years (standard deviation 5.82 years) were included in the study. In all cases, the clinical diagnosis was venous and lymphatic malformation. The radiological findings were dilated and tortuous vascular structures or multilobulated lesions with septa inside, with or without vascular flow; these findings allowed diagnosis in all cases. Treatment modalities included sclerotherapy in five patients, surgical resection in two, medical treatment with sirolimus in three, and surveillance in one. Subsequent clinical evolution was favorable in all patients, with decreased pain in six (partial in four and total in two) and size reduction in one patient.Conclusion: IVMs in our pediatric population most frequently affect the lower extremities. The main symptoms and signs were pain on exertion and volume increase. Treatment can be challenging given the extension and depth of the malformations, so a combination of therapeutic modalities may be necessary to obtain the best outcome.","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"81 5","pages":"280-286"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142387825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0