Boletín médico del Hospital Infantil de México最新文献

{"title":"Association between development level and nutritional status in children under 5 years of age in primary care.","authors":"Miguel Á Villasis-Keever, Antonio Rizzoli-Córdoba, Blanca B Mares-Serratos, Karla E Falcón-Millán, Edwin O Vargas-Ávila, Christian A Delaflor-Wagner, Daniel Aceves-Villagrán, Hortensia Reyes-Morales, José A García-Aranda","doi":"10.24875/BMHIM.25000004","DOIUrl":"10.24875/BMHIM.25000004","url":null,"abstract":"<p><strong>Background: </strong>Malnutrition is a risk factor for childhood development disorders. Although undernutrition is recognized as a public health problem, the impact of overweight/obesity on childhood development remains unknown. The objective is to determine the effects of undernutrition, overweight, and obesity on development in children aged between 1 and 59 months in rural/urban areas of Mexico.</p><p><strong>Methods: </strong>The Childhood Development Evaluation (EDI, for its acronym in Spanish) test was administered to children 1-59 months of age who visited primary care units in Guanajuato State, Mexico, between 2013 and 2015. The World Health Organization classification (weight/height ratio) was used for nutritional status. Logistic regression adjusted by sex, age, rural/urban, and level of marginalization, used to calculate odds ratios (OR) to stablish the association between nutritional status and developmental outcomes.</p><p><strong>Results: </strong>34,972 participants were included. 50.3% were male, 39.5% had a very low level of marginalization, 58.6% lived in urban areas, and 55.0% were beneficiaries of a conditional cash transfer program. Age distribution: 31.9% between 1 and 12 months old; 17.5% between 13 and 24 months old; 16.3% between 25 and 36 months old; and 34.3% between 37 and 59 months old. Overall 85.8% of participants had normal nutritional status, whereas 9.1% were identified as malnourished, and 5.0% were classified as overweight or obese. 79.1% had typical development. The OR for atypical development was 1.820 (95% confidence interval [95% CI], 1.671-1.981) for mild undernutrition; 2.796 (95% CI: 2.195-3.562) for moderate undernutrition; 14.903 (95% CI: 8.149-27.257) for severe undernutrition; and 1.160 (95% CI: 1.030-1.307) for overweight/obesity.</p><p><strong>Conclusion: </strong>Undernutrition and overweight/obesity are factors that increase the risk of developmental problems in children < 5 years of age.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 Supl 1","pages":"66-72"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tribute to Dr. Luis Velásquez Jones.","authors":"Mara Medeiros","doi":"10.24875/BMHIME.M24000072","DOIUrl":"https://doi.org/10.24875/BMHIME.M24000072","url":null,"abstract":"","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 1","pages":"5-6"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143596251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ibero-Latin American clinical practice guideline for the use of biotics in pediatric gastroenterology, hepatology, and nutrition: probiotics chapter.","authors":"Sylvia Cruchet, Rodrigo Vázquez, Roderick Bejarano, Celina Guzmán, Raquel Furnes, Michelle Higuera, Aldo Maruy, Fernando Medina, Marina Orsi, Luis Peña, Vera Lucia Sdepanian, Nelson Ramírez, José Spolidoro, Roberto Zablah, Christian Boggio-Marzet, Yael Encinas, Randall Quesada, Pedro Gutiérrez-Castrellón","doi":"10.24875/BMHIM.M25000043","DOIUrl":"10.24875/BMHIM.M25000043","url":null,"abstract":"<p><strong>Background: </strong>In Ibero-Latin America, the use of probiotics in pediatrics has increased in recent decades; however, clinical practice shows significant variability across countries and specialties. This situation prompted the development of a regional consensus based on the best available evidence and expert experience.</p><p><strong>Objective: </strong>To develop an Ibero-Latin American clinical practice guideline on the use of probiotics in pediatric gastroenterology, hepatology, and nutrition.</p><p><strong>Methods: </strong>A multidisciplinary panel of specialists from 12 countries, including gastroenterologists, hepatologists, nutritionists, and pediatricians, was convened. A systematic literature review was conducted in PubMed, Scopus, and Cochrane Library through December 2023. Evidence was assessed using the GRADE methodology, and key clinical questions were formulated. Recommendations were discussed and refined through a three-round Delphi process until consensus was reached.</p><p><strong>Results: </strong>Specific recommendations were developed for the use of probiotics in acute diarrhea, antibiotic-associated diarrhea, gastrointestinal infections, functional gastrointestinal disorders, and inflammatory diseases. Strains and doses with proven efficacy, such as Lactobacillus rhamnosus GG and Saccharomyces boulardii, were identified, and clinical scenarios where probiotic use is not justified were defined. The final consensus incorporated considerations of safety, applicability, and regional context.</p><p><strong>Conclusions: </strong>This guideline represents the first Ibero-Latin American collaborative effort to unify criteria for the use of probiotics in pediatrics, providing a practical and evidence-based framework to improve clinical care across the region.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 Supl 5","pages":"1-50"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145817668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cost-effectiveness of silver diamine fluoride for the prevention and control of early childhood caries: a scoping review.","authors":"Carmen D Macedo-Jaramillo, Estefany García-Cruz, Paulina De La Portilla-Robles, Daniela I Guadarrama-García","doi":"10.24875/BMHIM.24000090","DOIUrl":"10.24875/BMHIM.24000090","url":null,"abstract":"<p><p>Early childhood caries (ECC) is the presence of one or more decayed, missing, or filled teeth in children up to 71 months of age. Among the recommendations proposed by the World Health Organization to counteract this condition is the application of silver diamine fluoride (SDF). The aim of this research was to analyze the available information on the cost-effectiveness of SDF as a public health intervention in the prevention and control of ECC. This scoping review included articles published in English between 2008 and 2023 about the cost-effectiveness of SDF for pre-schoolers. Scientific journal databases (PubMed, Free Medical Journal, Science Direct, Springer Link, and Google Scholar) were searched using the following keywords: ECCs, effectiveness, cost, SDF, economic evaluation, caries, pre-school, infant, and minimal invasive treatment. The information extracted included author, year, objective, population, design, perspective of the analysis, options to be compared, time horizon, discount rate, costs, and effectiveness. We identified a total of 526 articles. Of these, 514 were excluded due to lack of relevance to the study objective, and 5 were duplicates. The final sample comprised 7 articles. The reported costs of SDF treatments from the perspective of healthcare practitioners ranged from $0.7 to $1,456, with an incremental cost-effectiveness ratio ranging from -$7.73 to -$518.50. SDF is a cost-effective treatment for public health interventions to prevent and control ECC in pre-schoolers.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 2","pages":"98-106"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pediatric arrhythmias: a comprehensive integrative review, symptom-based conceptual framework, and practical care guide.","authors":"Ana C Cepeda-Nieto, Corazón de J Roblero-Aguilar, Janetzy Martínez-López, Norma A Balderrábano-Saucedo","doi":"10.24875/BMHIM.24000059","DOIUrl":"10.24875/BMHIM.24000059","url":null,"abstract":"<p><p>Pediatric arrhythmia encompass a diverse array of conditions, ranging from asymptomatic cases to severe life-threatening episodes. Effective management of these conditions, especially for non-specialist physicians, is crucial to improving patient outcomes and reducing the risk of sudden cardiac death (SCD). This integrative review aims to synthesize the present evidence on the strategies for diagnosing and treating pediatric arrhythmias, providing a practical, symptom-based guide for non-specialist physicians. Following Cooper's methodological framework, we conducted a comprehensive literature search using electronic databases (PubMed/MEDLINE and Cochrane Library) up to August 7, 2024. Inclusion criteria focused on studies published between 2019 and 2024, involving pediatric patients aged 2-18 years with several types of arrhythmias, excluding those with congenital heart disease or other systemic conditions. Quality appraisal was performed using the GRADE and CONSORT methodologies. From 176 initially selected studies, 69 met the inclusion criteria. The evidence was synthesized into a symptom-based conceptual framework, categorizing arrhythmias into asymptomatic, paroxysmal tachycardia, and those associated with low cardiac output or syncope. Common arrhythmias, such as sinus arrhythmia, sinus bradycardia, and wandering atrial pacemaker typically do not require treatment. In contrast, conditions, such as supraventricular tachycardia, ventricular tachycardia, and inherited arrhythmias (e.g., long QT syndrome, Brugada syndrome) necessitate specific diagnostic and therapeutic strategies. This review provides a practical guide for non-specialist physicians to diagnose and manage pediatric arrhythmias, aiming to improve patient outcomes and reduce SCD incidence in children. Future research should focus on pediatric-specific studies and the development of novel therapeutic interventions.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 2","pages":"67-97"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parental knowledge and caregiving practices related to early childhood development.","authors":"Antonio Rizzoli-Córdoba, Alicia Lebrija-Hirschfield, Laura A Hernández-Trejo, Christian A Delaflor-Wagner, Miguel Á Villasis-Keever","doi":"10.24875/BMHIM.25000005","DOIUrl":"10.24875/BMHIM.25000005","url":null,"abstract":"<p><strong>Background: </strong>Early childhood development (ECD) is a critical period for achieving milestones in cognitive, motor, and socioemotional development. Parental knowledge of ECD influences the manner in which children are stimulated, as evidenced in previous studies, particularly in developing countries. This study examined parents' understanding of ECD, their stimulation and caregiving practices, and the sources of information that they utilize in the Mexican context.</p><p><strong>Methods: </strong>A descriptive cross-sectional field study was conducted using a questionnaire validated by a panel of experts and a pilot test. A total of 536 mothers and fathers from socioeconomic levels C-, D+, and D/E residing in three Mexican cities were surveyed using non-probability convenience sampling. The questionnaire inquired about respondents' knowledge, stimulation practices, and sources of information related to ECD.</p><p><strong>Results: </strong>In all, 60% of the surveyed parents did not consider the first 3 years of life as a relevant learning stage. Although 44.3% of mothers and 37.6% of fathers identified early learning (at 0-3 months), few socioemotional activities were considered relevant. Only 33% were familiar with the term \"early stimulation,\" and television was the most consulted medium (30%).</p><p><strong>Conclusions: </strong>It is necessary to raise awareness among parents about the importance of play, as well as socioemotional and communicative activities in ECD. The quality of information disseminated through mass media should be improved and public policies to strengthen parental education should be promoted.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 Supl 1","pages":"101-112"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COVID-19 infection and intense physical activity in hypokalemic periodic paralysis.","authors":"Francisco Cammarata-Scalisi, Esteban San Martín, Antonio Cárdenas-Tadich, Maykol Araya-Castillo, Carolina Peralta-Aros, Víctor Olivares, Enrico Bertini, Colin E Willoughby, Michele Callea","doi":"10.24875/BMHIM.24000070","DOIUrl":"10.24875/BMHIM.24000070","url":null,"abstract":"<p><strong>Background: </strong>Hypokalemic periodic paralysis (HPP) is a rare genetic neuromuscular disorder characterized by an autosomal dominant inheritance pattern and a variable clinical phenotype. It is associated with low potassium levels due to defects in muscle ion channels. HPP can be life-threatening, but it can be completely reversed if diagnosed and treated promptly and correctly. Pathogenic variants in a heterozygous in the CACNA1S or SCN4A genes lead to HPP.</p><p><strong>Clinical case: </strong>We present a 16-year-old male with a clinical history of flaccid paralysis associated with hypokalemia following intense physical activity and subsequent COVID-19 infection. During this evaluation, his 12-year-old maternal half-brother exhibited similar symptoms related to intense physical exercise. The affected mother, maternal aunt, and maternal grandfather have variable clinical histories. Genetic testing identified a heterozygous pathogenic variation in the CACNA1S gene (c.2700G>T; p.Arg900Ser) in the patient, his mother, and maternal half-brother.</p><p><strong>Conclusion: </strong>The availability of a positive family history facilitates diagnostic guidance and provides insight into the factors triggering crises. Education is the first step in contributing to prevention and management. Furthermore, understanding the etiological cause is crucial for offering available therapeutic options and providing family genetic counseling.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 4","pages":"252-257"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144882109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hemoptisis como síntoma inicial de carcinoma mucoepidermoide pulmonar en un niño.","authors":"Héctor Nuñez-Paucar, Noé Atamari-Anahui, Carla Cruzado-Villanueva, Víctor Gómez-Ponce","doi":"10.24875/BMHIM.24000136","DOIUrl":"https://doi.org/10.24875/BMHIM.24000136","url":null,"abstract":"<p><strong>Background: </strong>Pulmonary mucoepidermoid carcinoma is a rare neoplasm in children. Nonspecific symptoms such as hemoptysis may delay diagnosis because they are confused with other respiratory diseases.</p><p><strong>Clinical case: </strong>A 9-year-old male patient presented recurrent episodes of cough and hemoptysis. The patient had two similar episodes associated with wheezing in previous months and was treated as an asthma attack. Radiological studies and bronchoscopy reported a lung mass obstructing the left main bronchus, causing atelectasis and involvement of the left lung. Transthoracic biopsy was positive for a salivary gland tumor. Treatment was surgical (left pneumonectomy). Histopathological and immunohistochemical studies reported low-grade mucoepidermoid carcinoma. He did not receive chemotherapy. After two years of follow-up, the patient was asymptomatic, and we did not see any recurrence.</p><p><strong>Conclusions: </strong>Pulmonary mucoepidermoid carcinoma is rare in children. Hemoptysis and signs of bronchial obstruction may mimic other respiratory diseases, causing a delay in diagnosis. Treatment is surgical, with a good prognosis during follow-up.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 5","pages":"323-327"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145147792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Screen use and physical activity in children under 6 years old: what has changed after the COVID-19 pandemic?","authors":"María C Velázquez, Sandra V García, Diego J Salto, María A Ribeiro, Alberto E D'Agostino, Fernanda M Lardies-Arenas, Sílvia V Cuozzo, Emanuel L Castillo, Mauro F Andreu, Tatiana Dias-de Carvalho","doi":"10.24875/BMHIM.25000057","DOIUrl":"https://doi.org/10.24875/BMHIM.25000057","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Introducción: &lt;/strong&gt;Desde que los niños son pequeños tienen acceso a la tecnología. Debido al confinamiento en sus hogares, han modificado sus hábitos cotidianos, apropiándose de Internet como su fuente de juego, socialización y aprendizaje. Los objetivos de esta investigación son comparar los hábitos de uso de pantallas y de actividad física en niños menores de 6 años durante y después de la pandemia de COVID-19, y explorar los factores sociodemográficos de las personas cuidadoras y de los niños asociados a estos hábitos.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Métodos: &lt;/strong&gt;Estudio transversal, mediante encuesta anónima en línea a tutores legales y cuidadores de niños menores de 6 años de la región del Área Metropolitana de Buenos Aires, Argentina. Las encuestas se efectuaron en dos periodos: pandemia (aislamiento social, preventivo y obligatorio, entre los meses de agosto y octubre de 2020) y pospandemia (durante los meses de agosto a octubre de 2022).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Resultados: &lt;/strong&gt;Fueron respondidas 883 encuestas. Después de la pandemia disminuyó significativamente el las pantallas, y menor uso para videollamadas con familiares y para actividades escolares; por consecuencia, hubo un aumento de las horas de actividad lúdicas diarias. Los hábitos relacionados con el uso de pantallas y la actividad física están condicionados por características sociodemográficas tanto de las personas cuidadoras (sexo, lugar de residencia, cantidad de horas trabajadas e ingresos) como de los niños (edad y acceso a dispositivos con pantalla).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusiones: &lt;/strong&gt;Se observaron cambios favorables tras la pandemia de COVID-19 en los niños menores de 6 años, con una reducción en el tiempo de uso de pantallas y un aumento en el tiempo dedicado a actividad física. Sin embargo, la televisión y el smartphone permanecieron como los dispositivos más utilizados. Los hábitos de uso de pantallas y de actividad física se ven influenciados por las características sociodemográficas de las personas cuidadoras y de los niños.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Since children are young, they have access to technology. Due to confinement in their homes, they have modified their daily habits, appropriating the Internet as their source of play, socialization, and learning. The objectives of this study are to compare screen use and physical activity habits in children under 6 years of age during and after the COVID-19 pandemic, and explore the sociodemographic factors of caregivers and children associated with these habits.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A cross-sectional study using an anonymous online survey of legal guardians and caregivers of children under 6 years of age in the Buenos Aires Metropolitan Area, Argentina. The surveys were carried out in two periods: pandemic (social, preventive, and mandatory isolation, between the months of August and October 2020) and post-pandemic (during the months of August to October 2022).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;883 sur","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 6","pages":"375-386"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145843611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinicopathological correlation of neonatal lung ultrasound. A pictorial essay.","authors":"Daniel Ibarra-Ríos, Carlos A Serrano Bello, Deneb A Morales-Barquet, Talía Estrada-Rojas, Alejandra Sánchez-Cruz, Lourdes Ma Del C Jamaica-Balderas, Sergio A Patrón-Chi, Horacio Márquez-González","doi":"10.24875/BMHIM.25000085","DOIUrl":"https://doi.org/10.24875/BMHIM.25000085","url":null,"abstract":"<p><p>Lung ultrasound has become a valuable tool in neonatal intensive care practice, with exponential diffusion of evidence of its diagnostic and functional applications over the last decade. In this pictorial essay, we review animal models and clinical cases where diagnosis was confirmed with high-resolution pulmonary computed tomography/cardiac angiotomography, biopsies, or autopsies, pointing out the main ultrasound features of neonatal respiratory disorders.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 Supl 5","pages":"38-53"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145767101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}