Boletín médico del Hospital Infantil de México最新文献

{"title":"Tribute to Dr. Luis Velásquez Jones.","authors":"Mara Medeiros","doi":"10.24875/BMHIME.M24000072","DOIUrl":"https://doi.org/10.24875/BMHIME.M24000072","url":null,"abstract":"","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 1","pages":"5-6"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143596251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between development level and nutritional status in children under 5 years of age in primary care.","authors":"Miguel Á Villasis-Keever, Antonio Rizzoli-Córdoba, Blanca B Mares-Serratos, Karla E Falcón-Millán, Edwin O Vargas-Ávila, Christian A Delaflor-Wagner, Daniel Aceves-Villagrán, Hortensia Reyes-Morales, José A García-Aranda","doi":"10.24875/BMHIM.25000004","DOIUrl":"https://doi.org/10.24875/BMHIM.25000004","url":null,"abstract":"<p><strong>Background: </strong>Malnutrition is a risk factor for childhood development disorders. Although undernutrition is recognized as a public health problem, the impact of overweight/obesity on childhood development remains unknown. The objective is to determine the effects of undernutrition, overweight, and obesity on development in children aged between 1 and 59 months in rural/urban areas of Mexico.</p><p><strong>Methods: </strong>The Childhood Development Evaluation (EDI, for its acronym in Spanish) test was administered to children 1-59 months of age who visited primary care units in Guanajuato State, Mexico, between 2013 and 2015. The World Health Organization classification (weight/height ratio) was used for nutritional status. Logistic regression adjusted by sex, age, rural/urban, and level of marginalization, used to calculate odds ratios (OR) to stablish the association between nutritional status and developmental outcomes.</p><p><strong>Results: </strong>34,972 participants were included. 50.3% were male, 39.5% had a very low level of marginalization, 58.6% lived in urban areas, and 55.0% were beneficiaries of a conditional cash transfer program. Age distribution: 31.9% between 1 and 12 months old; 17.5% between 13 and 24 months old; 16.3% between 25 and 36 months old; and 34.3% between 37 and 59 months old. Overall 85.8% of participants had normal nutritional status, whereas 9.1% were identified as malnourished, and 5.0% were classified as overweight or obese. 79.1% had typical development. The OR for atypical development was 1.820 (95% confidence interval [95% CI], 1.671-1.981) for mild undernutrition; 2.796 (95% CI: 2.195-3.562) for moderate undernutrition; 14.903 (95% CI: 8.149-27.257) for severe undernutrition; and 1.160 (95% CI: 1.030-1.307) for overweight/obesity.</p><p><strong>Conclusion: </strong>Undernutrition and overweight/obesity are factors that increase the risk of developmental problems in children < 5 years of age.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 Supl 1","pages":"66-72"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parental knowledge and caregiving practices related to early childhood development.","authors":"Antonio Rizzoli-Córdoba, Alicia Lebrija-Hirschfield, Laura A Hernández-Trejo, Christian A Delaflor-Wagner, Miguel Á Villasis-Keever","doi":"10.24875/BMHIM.25000005","DOIUrl":"10.24875/BMHIM.25000005","url":null,"abstract":"<p><strong>Background: </strong>Early childhood development (ECD) is a critical period for achieving milestones in cognitive, motor, and socioemotional development. Parental knowledge of ECD influences the manner in which children are stimulated, as evidenced in previous studies, particularly in developing countries. This study examined parents' understanding of ECD, their stimulation and caregiving practices, and the sources of information that they utilize in the Mexican context.</p><p><strong>Methods: </strong>A descriptive cross-sectional field study was conducted using a questionnaire validated by a panel of experts and a pilot test. A total of 536 mothers and fathers from socioeconomic levels C-, D+, and D/E residing in three Mexican cities were surveyed using non-probability convenience sampling. The questionnaire inquired about respondents' knowledge, stimulation practices, and sources of information related to ECD.</p><p><strong>Results: </strong>In all, 60% of the surveyed parents did not consider the first 3 years of life as a relevant learning stage. Although 44.3% of mothers and 37.6% of fathers identified early learning (at 0-3 months), few socioemotional activities were considered relevant. Only 33% were familiar with the term \"early stimulation,\" and television was the most consulted medium (30%).</p><p><strong>Conclusions: </strong>It is necessary to raise awareness among parents about the importance of play, as well as socioemotional and communicative activities in ECD. The quality of information disseminated through mass media should be improved and public policies to strengthen parental education should be promoted.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 Supl 1","pages":"101-112"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Initial steps in the selection of a child development screening instrument in the peruvian context.","authors":"Carla P Cortez-Vergara, Gisely Hijar-Guerra, Blanca Távara-Campos, María E Ugaz-Villacorta","doi":"10.24875/BMHIM.24000156","DOIUrl":"https://doi.org/10.24875/BMHIM.24000156","url":null,"abstract":"<p><strong>Background: </strong>The foundational elements for optimal well-being and health are established during the early stages of life. When progress does not meet expectations, it is necessary to explore possible disorders, health conditions, or other probable factors affecting it. Health professionals in our country must have access to developmental screening instruments that facilitate early detection of these potential risks and delays, thus enabling timely intervention.</p><p><strong>Methods: </strong>After a pre-selection of the evidence and adequate training of a multi-sectoral panel, a virtual deliberative dialog was held with key stakeholders and decision-makers to determine the most appropriate development screening instrument for the Peruvian context. The evidence was analyzed and discussed in light of the established criteria. In addition, factors pertaining to implementation on a national level were discussed.</p><p><strong>Results: </strong>A set of instruments were obtained and prioritized in the following order: Evaluation of Child Development (EDI, Spanish acronym) ranked first, followed by the Abbreviated Developmental Scale Third Edition (EAD-3, Spanish acronym) and the Ages and Stages Questionnaire (ASQ-3, Spanish acronym), based on the established criteria. The primary components implicated in the execution of this evaluation on a national scale were subsequently identified.</p><p><strong>Conclusions: </strong>This deliberative dialog has enabled a first approach to the selection of a development screening instrument on the national level, providing valuable information to guide the implementation process.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 Supl 1","pages":"25-35"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Septic shock upon admission to pediatric intensive care units: prognostic analysis of mortality in a retrospective cohort.","authors":"Ricardo Rodriguez-Portilla, Isabel Pinedo-Torres, Claudia C Guerra-Ríos, Angela Parra Del Riego-Freundt-Thurne, Nilton Yhuri-Carreazo","doi":"10.24875/BMHIM.24000056","DOIUrl":"https://doi.org/10.24875/BMHIM.24000056","url":null,"abstract":"<p><strong>Background: </strong>Septic shock is a common cause of admission to pediatric intensive care units (PICU) and is associated with significant mortality. Our objective was to analyze the association between septic shock diagnosis at PICU admission and mortality during hospitalization.</p><p><strong>Method: </strong>This retrospective cohort study was conducted in the PICU of Hospital Nacional Edgardo Rebagliati Martins (HNERM) in Lima, Peru, from January 2018 to December 2021. The sample size was determined based on annual mortality rates, and randomization was used to create two groups: patients with and without septic shock. To evaluate mortality risk, we performed a Poisson regression with robust variances and 95% confidence intervals (CI) using both crude and adjusted models.</p><p><strong>Results: </strong>Of 1,341 patients admitted to the PICU during the study period, 358 were included in the analysis. The study population was 51.9% female, with a median age of 3.7 years. The largest age group was children under 1 year, comprising 29.6% of participants. The septic shock group showed higher rates of mechanical ventilation requirement, longer hospital stays, and increased mortality. The risk of mortality was 2.73 times higher in patients admitted with septic shock compared to those admitted with other diagnoses (relative risks: 2.73; 95% CI: 1.36-5.46).</p><p><strong>Conclusion: </strong>Patients admitted to the PICU with septic shock demonstrated a 2.73 times higher risk of death compared to those admitted for other reasons.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 1","pages":"28-34"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143596250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The first 1000 days: the great opportunity.","authors":"Marta M Zapata-Tarrés","doi":"10.24875/BMHIM.24000173","DOIUrl":"https://doi.org/10.24875/BMHIM.24000173","url":null,"abstract":"","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 Supl 1","pages":"1-2"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of a screening tool for developmental problems in children 60-71 months in Mexico.","authors":"María S Rodríguez-Trejo, Antonio Rizzoli-Córdoba, Laura A Hernández-Trejo, Ilma R Torres-Escobar, Miguel Á Villasis-Keever","doi":"10.24875/BMHIM.24000160","DOIUrl":"https://doi.org/10.24875/BMHIM.24000160","url":null,"abstract":"<p><strong>Background: </strong>Early childhood is a critical period for child development. The Child Development Evaluation Test (EDI in Spanish), developed and validated in Mexico, is a screening tool for developmental problems in children from 1 month to 4 years and 11 months.</p><p><strong>Objective: </strong>To validate group 15 of the EDI test for children aged 60-71 months, comparing sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) using the Battelle Developmental Inventory 2^nd edition (BDI-2) in Spanish as the gold standard.</p><p><strong>Methods: </strong>A cross-sectional analytic study with 46 children aged 60-71 months was conducted at the Hospital Infantil de México Federico Gómez. Children were evaluated using group 15 of the EDI test and BDI-2. The sample was non-probabilistic by convenience. Diagnostic metrics and comparisons were performed globally and in the developmental domain.</p><p><strong>Results: </strong>The sensitivity and specificity of group 15 for the EDI test were 93.8% (95% confidence interval [CI]: 81.8%-100%) and 73.3% (95%CI: 57.5%-89.1%), respectively. The PPV was 65.2%, and the NPV 95.5%. The highest percentage of false negatives was in the cognitive domain, followed by the adaptive domain.</p><p><strong>Conclusion: </strong>In this first study, group 15 of the EDI test shows high sensitivity and NPV, allowing early detection in an age group previously not covered, thus facilitating interventions in this group.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 Supl 1","pages":"45-51"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of a federal early education program in Mexico on the developmental level of children aged 13-48 months: national survey.","authors":"Antonio Rizzoli-Córdoba, Hortensia Reyes-Morales, Jesús H Trujillo-Flores, Mario R Paredes-Saldaña, Angélica Ocaña-Zavaleta, Laura A Hernández-Trejo, José A García-Aranda, Daniel Aceves-Villagrán, Miguel Á Villasis-Keever","doi":"10.24875/BMHIM.24000159","DOIUrl":"https://doi.org/10.24875/BMHIM.24000159","url":null,"abstract":"<p><strong>Background: </strong>Early childhood development is crucial. The objective of this study was to evaluate, on a national scale, the level of development of children enrolled in the federal childcare program, according to the length of stay in the childcare centers and by geographic area.</p><p><strong>Methods: </strong>A national cross-sectional study was conducted. The study population comprised 231,058 children aged between 13 and 48 months, enrolled in 9200-day care centers across the 32 states of Mexico. The developmental level was measured using the Child Development Evaluation test. The effect of length of stay was analyzed by logistic regression, using odds ratio of prevalence and 95% confidence intervals.</p><p><strong>Results: </strong>Of the total number of participants, 53% were male, and the 37-48 month-old group was the largest (45%, n = 103,976). The length of stay ranged from 1 to > 24 months. The proportion of children with normal developmental outcomes increased alongside the length of stay, from 72.3% for children with < 6 months of stay to 88.7% for those who attended centers for > 24 months. By geographical region, Guerrero and Oaxaca, two low-income states, showed the best results, along with the highest-income states. The distribution for each area of development and geographic area are shown.</p><p><strong>Conclusion: </strong>At the national level, long-term enrollment in daycare centers favors normal development. Particularly important is the high result in low-income regions, and it could be an equalizing strategy as a public policy. The different results among areas could help to improve the curricula.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 Supl 1","pages":"73-85"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibiotic therapy in dysentery of infectious etiology in early childhood: a systematic scoping review.","authors":"Juan F Guevara-Ramírez, Andrés F Rodríguez-Gutiérrez, Ingrid S Sánchez-Escobar, Samuel D Bolaños-Rodríguez, Valentina Adames-Restrepo, Simón A Ruiz-Galvis, Valentina Sánchez-Sánchez, Néstor A De La Cruz-Torres, Erwin H Hernández-Rincón, Samuel D Barbosa","doi":"10.24875/BMHIM.24000085","DOIUrl":"https://doi.org/10.24875/BMHIM.24000085","url":null,"abstract":"<p><p>Acute diarrhea (AD) is one of the leading causes of child mortality, particularly in children under 5 years old. Dysentery, a severe form of AD characterized by blood and mucus in the stool, raises controversies regarding the appropriate use of antibiotics. The objective of this manuscript is to synthesize the available information on the indications, risks, and benefits of antibiotics used in infectious dysentery during early childhood. A scoping systematic review was conducted using international reference documents and the databases PubMed, Scopus, and Google Scholar, following the PRISMA-ScR guidelines. Studies from 2014 onwards that addressed antibiotic management in children under 5 years old with bacterial or parasitic dysentery were included. Among the 39 selected studies, the evidence shows limited benefits and significant risks associated with antibiotic use, with recommendations varying based on specific etiology and the patient's clinical conditions, where it is evident that the rational use of antibiotics in pediatric dysentery is crucial to avoid bacterial resistance and adverse effects. There is a need for future research to establish guidelines based on robust clinical trials, to optimize targeted treatment and improve clinical outcomes in this population.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 1","pages":"15-27"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143596234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cost-effectiveness analysis of child development evaluation test (CDE test or Prueba EDI) in children under 5 years old in Mexico: a simulation model study.","authors":"José R García-Lira, Rita E Zapata-Vázquez, Alfonso Reyes-López, Antonio Rizzoli-Córdoba","doi":"10.24875/BMHIM.24000171","DOIUrl":"https://doi.org/10.24875/BMHIM.24000171","url":null,"abstract":"<p><strong>Background: </strong>The Health Ministry has incorporated the Child Development Evaluation test (CDE test) as the national screening tool for children < 5 years old. The aim of this study is to analyze the cost-effectiveness of the CDE test compared to standard medical consultation in Mexico.</p><p><strong>Methods: </strong>The study was conducted with information available until 2020. A cost-effectiveness analysis was conducted from perspective of the public/social sectors in Mexico with a decision tree model to evaluate the strategies. The time horizon was set at 1 year, no discounting applied. Costs were calculated in Mexican pesos (MXN) at 2019 prices and included both direct/indirect costs. Direct costs encompassed CDE test administration, specialist consultations, and rehabilitation sessions. Indirect costs considered transportation expenses and lost wages related to caregiving. To account for variability and uncertainty, a Monte Carlo simulation with 10,000 iterations was performed. Probabilistic sensitivity analysis was conducted to test robustness of the results.</p><p><strong>Results: </strong>The results confirm that the CDE test consistently outperforms the standard approach, delivering improved outcomes at reduced costs in the majority of scenarios. The incremental net monetary benefit of implementing CDE screening was $44,608 MXN (2019 value), providing additional evidence of its cost-effectiveness.</p><p><strong>Conclusion: </strong>This study suggests that the CDE test is cost-saving from the public and social sector perspective, generating a net increase in both monetary benefits and health outcomes. Furthermore, its implementation is feasible within the Mexican healthcare system, particularly considering its potential to enhance long-term efficiency.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 Supl 1","pages":"59-65"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}