Boletín médico del Hospital Infantil de México最新文献

{"title":"Cross-cultural adaptation, validation, and reliability of the child development evaluation test (EDI) in Colombia.","authors":"Luisa M Salamanca-Duque, Ma Mercedes Del C Naranjo-Aristizábal, Luz A Botero-Montoya, Luz Ma Velásquez-Palacio, Sandra Garnica-López, Ma Angélica Enciso-Rodríguez, Yadira Henao-Valencia, Antonio Rizzoli-Córdoba","doi":"10.24875/BMHIM.24000155","DOIUrl":"https://doi.org/10.24875/BMHIM.24000155","url":null,"abstract":"<p><strong>Background: </strong>Monitoring child development requires not only the determination of developmental milestones but also surveillance and continuous monitoring, hence the importance of having valid and reliable evaluation instruments. This research aimed to cross-culturally adapt the Child Development Evaluation (CDE) test for Colombia and determine its validity and reliability.</p><p><strong>Methods: </strong>The cross-cultural adaptation process was conducted in four phases: I. Adaptation to Colombian Spanish: adjustments of the test to Colombian Spanish and analysis of equivalences; II. Content and face validity: evaluation by five expert judges who performed quantitative and qualitative assessments of the test; III. Review by the original author; IV. Pilot test. Reliability analyses for internal consistency and intra-rater reliability were performed.</p><p><strong>Results: </strong>For the adaptation to Colombian Spanish, most test items were equivalent to Mexican Spanish, with some requiring minimal conceptual and contextual changes to maintain their meaning; culturally relevant formulations and expressions were adjusted. In the content and face validity assessment, adequate results were found regarding the importance, influence, and observability of the items. Internal consistency reliability was moderate, with Cronbach's α values between 0.41 and 0.57, and intra-rater reliability was very good, with Kappa index values > 0.76.</p><p><strong>Conclusion: </strong>The CDE test demonstrates cross-cultural adaptation, content and face validity, and reliability for its application and use in Colombia.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 Supl 1","pages":"36-44"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hemodynamic phenotypes in congenital diaphragmatic hernia and their association with morbidity and mortality.","authors":"Daniel Ibarra-Ríos, José G Mantilla-Uresti, Diana M Barrios-Bautista, Alejandro Peñarrieta-Daher, Cristian R Zalles-Vidal, Deneb A Morales-Barquet, Horacio Márquez-González","doi":"10.24875/BMHIM.24000093","DOIUrl":"https://doi.org/10.24875/BMHIM.24000093","url":null,"abstract":"<p><strong>Background: </strong>Congenital diaphragmatic hernia (CDH) is a severe condition associated with high morbidity and mortality. Its severity correlates with the degree of pulmonary hypoplasia. Recent literature has emphasized the importance of identifying distinct hemodynamic phenotypes (HP) to guide physiology-based management.</p><p><strong>Method: </strong>We included all CDH patients evaluated by targeted neonatal echocardiography from January 2017 to April 2022. HPs were classified into three groups: HP1 (mild pulmonary hypertension [PH] without ventricular dysfunction), HP2 (pre-capillary PH), and HP3 (post-capillary PH). We compared differences between survivors and non-survivors using the Mann-Whitney U-test, analyzed baseline and pre/post-surgical echocardiographic parameters using the Wilcoxon test, estimated survival curves using Kaplan-Meier analysis, and compared length of stay using the Kruskal-Wallis test.</p><p><strong>Results: </strong>Among 28 included neonates, 24 survived (86%). HP distribution was: HP1 9 patients (32%), HP2 8 patients (29%), and HP3 11 patients (39%). Four patients died, two post-surgery and two without surgical intervention. Mortality-associated factors included higher pCO₂, lower left ventricular (LV) output, decreased LV compliance, and elevated pulmonary vascular resistance (PVR). Survival analysis revealed a non-significant trend toward higher mortality in HP2 (one death) and HP3 (three deaths). Follow-up demonstrated progressive increases in biventricular output, PVR reduction, and compensatory cerebral vasodilation.</p><p><strong>Conclusion: </strong>HP correlated with patient mortality, particularly in cases with greater pulmonary hypoplasia (higher CO₂) and compromised ventricular performance. Echocardiographic monitoring revealed improvements in biventricular performance, decreased PVR facilitating surgical intervention, and cerebral perfusion adaptation.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 1","pages":"54-62"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143596165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acknowledgments to reviewers 2024.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 1","pages":"1-2"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143596231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mitochondria-based medicine.","authors":"Salvador Vázquez-Vega, José D Martínez-Ezquerro, Sergio Sánchez-García, Edwin R Marka-Castro, Fernando Minauro-Sanmiguel","doi":"10.24875/BMHIM.24000058","DOIUrl":"https://doi.org/10.24875/BMHIM.24000058","url":null,"abstract":"<p><p>At the balance between human health and disease (from the very first moments to the end of life), the mitochondrion is central players because of its metabolic role in adenosine triphosphate synthesis, cell signaling, immune response, and other processes of clinical interest. On the other hand, impairments at the optimal mitochondria function have important consequences in complex diseases, such as heart disease, diabetes, and cancer, among others. These mitochondrial impairments can occur at any age damaging multiple body systems, which have prompted the mitochondrial medicine development. Since mitochondrial diseases have great variability in their clinical manifestations, early studies were centered on mitochondriopathies, however nowadays, this focus has broadened to understand and encompass the mitochondrial role of in diseases development of both pediatric and adult age. The mitochondria potential to improve diagnostic, prognostic, and treatment response strategies has been revealed by experimental approaches using proteomics, genomics, and metabolomics to identify clinical biomarkers showing disease development. Thus, the perspective of mitochondria-based medicine recognizes the importance of generating scientific evidence related to mitochondria and their role in pathological conditions from a comprehensive approach.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 1","pages":"7-14"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143596248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of 6 months of permanence in an early intervention program on the developmental level of children 18-42 months of age in poverty: cohort study.","authors":"Miguel Á Villasis-Keever, Jesús H Trujillo-Flores, Angélica Ocaña-Zavaleta, Perla Ma Ortega-Lomelín, Christian A Delaflor-Wagner, Alejandro I Soto-Briseño, Laura A Hernández-Trejo, José A García-Aranda, Daniel Aceves-Villagrán, Hortensia Reyes-Morales, Antonio Rizzoli-Córdoba","doi":"10.24875/BMHIM.24000167","DOIUrl":"https://doi.org/10.24875/BMHIM.24000167","url":null,"abstract":"<p><strong>Background: </strong>The Child Care Facilities Program (PEI, for its Spanish acronym) in Mexico targets parents of children aged 1-3 years living in poverty, providing education and care strategies 5 days a week. This study aimed to evaluate the impact of a 6-month stay in childcare centers on the developmental levels of children under 4 years old.</p><p><strong>Methods: </strong>A longitudinal, before-and-after study was conducted. Children aged 12-42 months enrolled in the PEI were included in the study. All participants remained in the program for 6 months from the first measurement. The overall and area-specific developmental levels were assessed using the Early Childhood Development Assessment (EDI, for its Spanish acronym) test. The percentages of developmental levels (normal, delayed, and at risk of delay) were compared between the baseline and 6-month assessments using the McNemar test.</p><p><strong>Results: </strong>The study included 1835 children, of whom 52% were male. The age distribution was as follows: 28.1% were 12-24 months old, 48.4% were 25-36 months old, and 23.5% were 37-42 months old. At baseline, 80.5% (n = 1,476) of the children were classified as having normal overall development, 16% had developmental delay, and 3.5% were at risk for delay. After 6 months, the percentage of children with normal development increased to 90.1%, while those with developmental delay and those at risk for delay decreased to 8.7% and 1.2%, respectively. Similar improvements were observed across various developmental areas, except in the knowledge area.</p><p><strong>Conclusions: </strong>A 6-month stay in childcare centers is beneficial for improving the developmental levels of children under 4 years old, both overall and in motor, language, social, and cognitive areas.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 Supl 1","pages":"86-93"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Play prescription: intervention delivered at primary health care facilities to promote child development through activities at home.","authors":"Antonio Rizzoli-Córdoba, Martha C Campos-Maldonado, Víctor H Vélez-Andrade, Christian A Delaflor-Wagner, Laura A Hernández-Trejo, Daniel Aceves-Villagrán, Miguel Á Villasis-Keever","doi":"10.24875/BMHIM.24000164","DOIUrl":"https://doi.org/10.24875/BMHIM.24000164","url":null,"abstract":"<p><strong>Background: </strong>Play is a fundamental component of children's social, emotional, cognitive, and physical development. This study focused on assesses a play-based intervention method to promote overall child development based on parental involvement, delivered at primary care facilities.</p><p><strong>Methods: </strong>Quasi-experimental study was conducted with children 24-59 months old, regularly attending the monthly stimulation sessions in primary care facilities in the state of Puebla, Mexico, from November 2015 to April 2016. Play interventions were administered over six sessions each month 1-h length individually for the dyad, included free play time, and each session one activity at home that include the five areas of development and with some materials provided but encouraged to use more available at home. The Child Development Evaluation (EDI) test was administered at baseline, 3 and 6 months after the intervention. A comprehensive data set encompassing demographic variables was collected and analyzed. McNemar test was used to assess developmental changes over time.</p><p><strong>Results: </strong>The sample consisted of 276 children, 60.5% were male, median age 40 months (interquartile range: 34-46). All participants attend the six sessions and conducted activities daily at home. Overall, the percentage of children with abnormal result with EDI test was 77.2% at baseline and 17.4% final measurement at 6 months (p < 0.001), with mild-delay decreased from 39.9% to 6.9% and high-risk of delay from 37.3% to 10.5%.</p><p><strong>Conclusion: </strong>The play intervention resulted in a clinically and statistically significant improvement in the developmental outcomes of the children, both with normal/abnormal result at baseline.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 Supl 1","pages":"94-100"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The future of children is always today.","authors":"Helia Molina-Milman","doi":"10.24875/BMHIM.24000172","DOIUrl":"https://doi.org/10.24875/BMHIM.24000172","url":null,"abstract":"","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 Supl 1","pages":"3-4"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Developmental and behavioral pediatrics service: comprehensive early childhood care in Mexico.","authors":"Lizbeth G Salado-Meléndez, Antonio Rizzoli-Córdoba, Leopoldo Alfonso Cruz-Ortiz","doi":"10.24875/BMHIM.24000165","DOIUrl":"https://doi.org/10.24875/BMHIM.24000165","url":null,"abstract":"<p><p>Developmental pediatrics (DP) in Mexico has taken a crucial step forward in the creation of the Developmental and Behavioral Pediatrics Service (SPDC, for its acronym in Spanish) at Hospital Infantil de México Federico Gómez (HIMFG). The SPDC is a leading area in early detection and intervention in neurodevelopmental problems and contributes to children's well-being. Among its achievements are the development and implementation of the Child Development Evaluation Test, which has been validated for children under 6 years old, and of a free virtual training program for medical personnel that is supported by an interactive platform. Furthermore, the SPDC is the only center in Mexico to offer a postgraduate degree in DP. With a fair and evidence-based approach, the SPDC contributes to the strengthening of public policy, research, and comprehensive care to ensure children's development.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 Supl 1","pages":"113-119"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics of preterm infants in pediatric rehabilitation at a referral hospital in Peru.","authors":"Roger De la Cerna-Luna, Walter Chacon-Obregon, Paola Del Carpio-Samaniego, Ana Igei-Chiney, Alvaro Taype-Rondan","doi":"10.24875/BMHIM.24000113","DOIUrl":"10.24875/BMHIM.24000113","url":null,"abstract":"<p><strong>Background: </strong>Prematurity is associated with a higher risk of disability. However, no studies on this population in rehabilitation settings in Peru have been found. This study aims to describe the characteristics of preterm infants at the Pediatric Rehabilitation Service of Hospital Nacional Edgardo Rebagliati Martins (SRP-HNERM).</p><p><strong>Method: </strong>A cross-sectional descriptive study was conducted. Medical records of preterm infants at SRP-HNERM from September 2023 to February 2024 were reviewed. The Hammersmith Infant Neurological Examination (HINE), General Movements Assessment (GMA), and other outcome measures were used for evaluation.</p><p><strong>Results: </strong>A total of 158 preterm infants were evaluated. During hospitalization, 51.3% were evaluated by a physiatrist, 47.5% received physical therapy, and 51.3% had feeding and swallowing disorders (FSD). After discharge, all patients were evaluated by a physiatrist at SRP-HNERM. Among infants with ≥ 44 weeks of corrected gestational age (CGA), 48.1% showed some degree of developmental delay, with global delay present in 34%. Of those with ≥ 48 weeks of CGA, 54.9% had an optimal HINE score. Normal GMA was observed in 51.2% of infants with ≤ 5 months of CGA. A higher frequency of global developmental delay was found in infants who had FSD during hospitalization and a lower frequency in those who had neonatal jaundice.</p><p><strong>Conclusions: </strong>Slightly more than half of the preterm infants were evaluated by a physiatrist, had FSD during hospitalization, had an optimal HINE score at ≥ 48 weeks of CGA, and had a normal GMA at ≤ 5 months of CGA. The presence of FSD during hospitalization should alert clinicians to a higher risk of global developmental delay in this population.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 1","pages":"44-53"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143596161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hydrocele of the canal of Nuck: a case report of an unusual disease.","authors":"Bruna Suda-Rodrigues, Ma Beatriz Ferraz-Cabral da Ponte, Márcio L Duarte, Élcio R Duarte","doi":"10.24875/BMHIM.24000078","DOIUrl":"https://doi.org/10.24875/BMHIM.24000078","url":null,"abstract":"<p><strong>Background: </strong>Hydrocele of the canal of Nuck is a rare pathology with a prevalence of approximately 1% in females aged 0-16 years. Its prevalence in adults remains unknown. The condition develops due to persistent patency or failed obliteration of the canal of Nuck. Several factors may contribute to its development, including lymphatic disorders, trauma, infection, inflammation, or idiopathic causes. Clinically, it presents as edema in the groin or genital region without additional symptoms. Ultrasonography is the preferred diagnostic modality for hydrocele of the canal of Nuck.</p><p><strong>Case report: </strong>We present the case of a 20-month-old female patient who presented with pain and a \"lump\" in the right inguinal region for 3 days. The patient was diagnosed with type 1 hydrocele of the canal of Nuck through ultrasonography, which was subsequently confirmed during surgery. The patient was discharged on the same day as the procedure and remains asymptomatic.</p><p><strong>Conclusions: </strong>Although rare, hydrocele of the canal of Nuck should be considered in the differential diagnosis of groin or genital region edema presenting without additional symptoms. Its diagnosis can be challenging due to several common differential diagnoses, including indirect inguinal hernia, tumors, cysts, abscesses, and lymphadenopathies, which occur more frequently. Therefore, ultrasonography plays a crucial role in evaluating these differential diagnoses and confirming the hydrocele of the canal of Nuck.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"82 1","pages":"63-66"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143596170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}