BMC Oral Health最新文献

{"title":"Comparison of total treatment duration with hybrid pendulum and buccal interradicular miniscrew supported maxillary molar distalization mechanics: a retrospective study.","authors":"Berrak Çakmak, Selin Kale Varlık, Tuba Tortop","doi":"10.1186/s12903-025-06714-8","DOIUrl":"https://doi.org/10.1186/s12903-025-06714-8","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this retrospective cohort study was to compare the total duration of Class II malocclusion treatment with hybrid pendulum vs. buccal interradicular miniscrew supported distalization mechanics followed by fixed appliances. Molar distalization duration and end-of-the-treatment changes were also compared.</p><p><strong>Materials and methods: </strong>The sample of this retrospective cohort study consisted of clinical records, pre-treatment (T1) and post-treatment (T2) dental models, and panoramic and lateral cephalometric radiographs of 80 skeletal Class I patients with bilateral Class II molar relation. Molar distalization was achieved with a hybrid pendulum in Group P (15 males, 25 females; mean age: 15.19 ± 0.32 years) and with buccal interradicular miniscrew-supported compressed sentalloy coil springs in Group B (15 males, 25 females; initial mean age: 15.65 ± 0.32 years). Following molar distalization, all patients in both groups received comprehensive fixed orthodontic treatment. Molar distalization and total treatment durations and changes in Peer Assessment Rating scores and 14 cephalometric measurements were evaluated.</p><p><strong>Results: </strong>Statistically significant molar distalization and distal tipping, mandibular incisor protrusion, and PAR reduction were achieved in both groups, with no difference between groups. There were no significant differences between groups for total treatment (24.58 ± 5.19 months in Group B and 24.81 ± 5.33 months in Group P) and molar distalization durations (7.01 ± 2.17 months in Group B and 7.03 ± 1.42 months in Group P) (p > 0.0167).</p><p><strong>Conclusions: </strong>The total length of orthodontic treatment for Class II malocclusion which involved molar distalization by miniscrew supported appliances was not affected by whether the appliance was located palatally or buccally.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"1348"},"PeriodicalIF":3.1,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12369126/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144942325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and verification of a convolutional neural network-based model for automatic mandibular canal localization on multicenter CBCT images.","authors":"Xiao Pan, Chengtao Wang, Xuhui Luo, Qi Dong, Haiyang Sun, Wentao Zhang, Hongyan Qu, Runzhi Deng, Zitong Lin","doi":"10.1186/s12903-025-06724-6","DOIUrl":"https://doi.org/10.1186/s12903-025-06724-6","url":null,"abstract":"<p><strong>Objectives: </strong>Development and verification of a convolutional neural network (CNN)-based deep learning (DL) model for mandibular canal (MC) localization on multicenter cone beam computed tomography (CBCT) images.</p><p><strong>Methods: </strong>In this study, a total 1056 CBCT scans in multiple centers were collected. Of these, 836 CBCT scans of one manufacturer were used for development of CNN model (training set: validation set: internal testing set = 640:360:36) and an external testing dataset of 220 CBCT scans from other four manufacturers were tested. The convolution module was built using a stack of Conv + InstanceNorm + LeakyReLU. Average symmetric surface distance (ASSD) and symmetric mean curve distance (SMCD) were used for quantitative evaluation of this model for both internal testing data and partial external testing data. Visual scoring (1-5 points) were performed to evaluate the accuracy and generalizability of MC localization for all external testing data. The differences of ASSD, SMCD and visual scores among the four manufacturers were compared for external testing dataset. The time of manual and automatic MC localization were recorded.</p><p><strong>Results: </strong>For the internal testing dataset, the average ASSD and SMCD was 0.486 mm and 0.298 mm respectively. For the external testing dataset, 86.8% CBCT scans' visual scores ≥ 4 points; the average ASSD and SMCD of 40 CBCT scans with visual scores ≥ 4 points were 0.438 mm and 0.185 mm respectively; there were significant differences among the four manufacturers for ASSD, SMCD and visual scores (p < 0.05). And the time for bilateral automatic MC localization was 8.52s (± 0.97s).</p><p><strong>Conclusions: </strong>In this study, a CNN model was developed for automatic MC localization, and external testing of large sample on multicenter CBCT images showed its excellent clinical application potential.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"1352"},"PeriodicalIF":3.1,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12369139/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144942338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital measurement of tooth wear in sleep bruxism patients wearing occlusal splints.","authors":"Irene Laksamikeeratikul, Supawadee Jariyasakulroj, Thiprawee Chattrattrai, Sunee Pongrojpaw","doi":"10.1186/s12903-025-06716-6","DOIUrl":"https://doi.org/10.1186/s12903-025-06716-6","url":null,"abstract":"","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"1349"},"PeriodicalIF":3.1,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12369210/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144942375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Root and canal morphology of mandibular second molars in a Chinese Kazakh population by cone-beam computed tomography.","authors":"Shuchun Yang, Chenye Li, Hui Shi, Ming Liu, Xu Wang","doi":"10.1186/s12903-025-06727-3","DOIUrl":"https://doi.org/10.1186/s12903-025-06727-3","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to investigate variations in root and canal morphology of the mandibular second molars in a Chinese Kazakh population using cone-beam computed tomography (CBCT).</p><p><strong>Methods: </strong>A total of 374 mandibular second molars from 236 patients were included in the retrospective study. The mandibular second molars were categorized based on the radiographic morphology of their external roots: non-fused roots (NFR), fused roots (FR), and single roots with a single canal (SS). The configuration of the C-shaped canal at three different levels was categorized into C1-C5. A chi-square test was employed to assess the association between the incidence of C-shaped root canals and demographic factors such as sex and tooth position.</p><p><strong>Results: </strong>Mandibular second molars typically had two roots. C-shaped root canals appeared in 33.1% of second molars. The C-shaped form was most prominent in C3, followed by C1. Sex and tooth position did not exhibit notable differences.</p><p><strong>Conclusions: </strong>The incidence of C-shaped root canals in the Chinese Kazakh population was similar to that previously reported in Asian populations and higher than in Caucasian and Middle Eastern populations.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"1347"},"PeriodicalIF":3.1,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12369240/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144942328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ANO5 p.I616F variant drives florid cemento-osseous dysplasia by disrupting transmembrane domain structure.","authors":"Lanlan Zhang, Wenxi Jin, Yunfa Qin, Yonghui Zhang, Yemei Qian, Jingyi Li, Yu Liu, Yan'an Shi, Rongju Xie, Weihong Wang","doi":"10.1186/s12903-025-06717-5","DOIUrl":"https://doi.org/10.1186/s12903-025-06717-5","url":null,"abstract":"","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"1345"},"PeriodicalIF":3.1,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12369069/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144942377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the efficacy of clear aligners in mandibular advancement and their effect on mandibular trabecular structures using fractal dimension analysis.","authors":"Nurver Karslı, Merve Gonca, Gizem Mine Türksever, Nesrin Atasaral Beyaz","doi":"10.1186/s12903-025-05925-3","DOIUrl":"https://doi.org/10.1186/s12903-025-05925-3","url":null,"abstract":"<p><strong>Background: </strong>The objective of this study was to evaluate the efficacy of the mandibular advancement protocol (MA) with clear aligners in the treatment of skeletal Class II malocclusion and to assess their effect on the mandibular trabecular structure using fractal dimension analysis (FD-A) on panoramic radiographs.</p><p><strong>Methods: </strong>The study included panoramic and cephalometric radiographs of 20 patients (treatment group, mean age: 11.7 ± 0.8 years; 9 girls, 11 boys) with Class II malocclusion, treated with the mandibular advancement protocol (MA) using clear aligners. The radiographs were obtained before treatment (T0) and following the MA phase (T1). Additionally, panoramic radiographs of 20 control subjects who had undergone no orthodontic treatment (control group, mean age: 11.7 ± 0.9 years; 9 girls, 11 boys) were analyzed. The fractal dimension values of the mandibular trabecular structures in the condylar, gonial, and corpus regions were evaluated for both groups. Statistical analyses were performed using paired t-test and independent samples t-test for parametric data, and Wilcoxon test and Mann-Whitney U test for non-parametric data. Statistical significance was set at P < 0.05.</p><p><strong>Results: </strong>The treatment applied using MA with aligners resulted in significant decreases in SNA (P < 0.05), ANB (P < 0.05), 1-NA (P < 0.001), overjet (P < 0.001), and overbite (P < 0.01). Conversely, significant increases were observed in S-Go (P < 0.01) and 1-NB (P < 0.05) parameters. The FD-A changes between T0 and T1 indicated that the observed increases in the right and left condylar processes, the left gonial region, and the left mandibular corpus were not statistically significant in the treatment group (P > 0.05). The comparison of the FD-A results between the groups revealed no statistically significant differences (P > 0.05).</p><p><strong>Conclusions: </strong>The FD-A results revealed no significant alterations in the trabeculation of the mandibular bone in the treatment group. These findings suggest that MA treatment with aligners primarily contributes to dental correction rather than inducing changes in the skeletal structure and trabeculation of the mandibular bone.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"1351"},"PeriodicalIF":3.1,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12369222/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144941787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The regulatory role of oxidative stress in the tooth movement process of rats with chronic fluorosis.","authors":"Lingyan Lai, Wanxin Chen, Yue Hao, Bo Chen, Hua Yang","doi":"10.1186/s12903-025-06599-7","DOIUrl":"https://doi.org/10.1186/s12903-025-06599-7","url":null,"abstract":"<p><strong>Background: </strong>Clinically, fluorosis patients exhibit delayed orthodontic tooth movement and compromised retention. Experimental studies in fluorosis-exposed rats demonstrate suppressed tooth movement, impaired periodontal angiogenesis, and downregulated VEGF/PI3K/AKT/eNOS signaling. Oxidative stress is critical in periodontal remodeling during orthodontic treatment, yet its role in fluorosis-related movement alterations remains unclear.</p><p><strong>Methods: </strong>Seventy 3-week-old Sprague-Dawley rats (body weight 60 ± 5 g) were randomly allocated into experimental groups. Ten rats served as a baseline group (0 day). The remaining 60 were randomized into three groups: control (C), orthodontic (O), and fluorosis orthodontic (FO), (n = 20 rats), subdivided into 3, 7, 14, and 21 days subgroups. C, O groups and blank baseline subgroup received purified water (fluoride < 0.08 mg/L, below the national standard of 1 mg/L), the FO group and fluorosis baseline subgroup drank 150 mg/L NaF water to establish a fluorosis model. After 3 months, orthodontic appliances were applied to O and FO groups. Fluoride accumulation (blood/urine), tooth movement rate and oxidative stress markers (SOD, CAT, MDA, and 8-OHdG) were analyzed.</p><p><strong>Results: </strong>1 FO group showed elevated blood/urine fluoride levels with C group (P < 0.05). Successful tooth movement was confirmed by interdental expansion.2 FO group exhibited slower tooth movement rate than O group (P < 0.05)0.3 Oxidative stress dynamics: Intergroup Difference: SOD and CAT levels were lowest in the FO group before 7 days, while MDA and 8-OHdG levels were highest in the FO group (P < 0.05), with differences narrowing in later stages.Intragroup Comparisons: SOD: C group: Levels initially increased, peaked at 14 days, and subsequently declined.O group: Levels consistently decreased over time.FO group: Levels exhibited a continuous upward trend.CAT: C group: Levels fluctuated in the early phase and sharply increased in the later phase.O group: Levels initially rose and then declined.FO group: Levels persistently increased throughout the study.MDA: C and FO groups: Levels continuously decreased.O group: Levels first increased, then decreased with fluctuations.8-OHdG: C group: Levels initially rose and later declined.O group: Levels fluctuated markedly.FO group: Levels first decreased and then slightly rebounded.</p><p><strong>Conclusion: </strong>Fluorosis inhibits early-stage tooth movement (3-7 days) through aggravated oxidative stress, with diminishing effects over time as compensatory antioxidant mechanisms emerge.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"1344"},"PeriodicalIF":3.1,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12366193/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144942019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Autonomous robotic system-assisted trans-inferior alveolar nerve implantation for patient diagnosed with pemphigoid: a case report.","authors":"Mucong Li, Huixin Lv, Yidi Zhang, Xiuyu Liu, Kewen Jia, Jiaqian You, Siyu Chen, Yanmin Zhou","doi":"10.1186/s12903-025-06705-9","DOIUrl":"https://doi.org/10.1186/s12903-025-06705-9","url":null,"abstract":"<p><strong>Background: </strong>Inadequate bone height and the proximity of the inferior alveolar nerve following vertical resorption of the mandibular alveolar ridge pose great challenges for dental implant surgery. Pemphigoid is a chronic autoimmune disease affecting both the skin and mucous membranes. The presence of autoantibodies and the ongoing inflammatory response significantly impair the skin's ability to heal in pemphigoid patients, thus necessitating a minimally invasive surgical approach. Therefore, finding accurate and minimally invasive implant solutions to address insufficient bone height in the mandibular posterior region for pemphigoid patients is highly important.</p><p><strong>Case presentation: </strong>A 35-year-old female patient with pemphigoid presented with multiple missing posterior mandibular teeth requested dental implants. CBCT examination revealed substantial vertical resorption of the mandible in the right posterior region. Taking into account the patient's overall health condition, potential surgical trauma, and treatment duration, an autonomous dental implant robot was utilized to perform trans-inferior alveolar nerve implantation.</p><p><strong>Conclusion: </strong>Autonomous robotic system-assisted trans-inferior alveolar nerve implantation not only maximized the use of the patient's existing bone volume and shortened the treatment period but also ensured the precision of implant placement. At the same time, the flap range of the implant surgery was greatly reduced, thereby decreasing the risk of postoperative soft tissue complications for patients with pemphigoid.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"1343"},"PeriodicalIF":3.1,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12366348/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144942342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The toxic effect of titanium dioxide nanoparticles on rat submandibular salivary glands and the protective role of vitamin E.","authors":"Mariam Aboayana, Yasmine M Tolba","doi":"10.1186/s12903-025-06631-w","DOIUrl":"https://doi.org/10.1186/s12903-025-06631-w","url":null,"abstract":"<p><strong>Background: </strong>To assess the impact of titanium dioxide nanoparticles (TiO₂NPs) on submandibular salivary glands and the role of vitamin E in preventing this cytotoxicity.</p><p><strong>Methods: </strong>Thirty adult male albino rats were randomly divided into 3 groups: Negative control received olive oil for 3 weeks; Study I received olive oil for 1 week, then daily oral administration of 300 mg/kg TiO₂NPs for 2 weeks; and Study II received 100 mg/kg vitamin E diluted in 100 ml olive oil daily as a prophylactic from day 1 for 3 weeks. On day 8, with vitamin E, they received 300 mg/kg TiO₂NPs for 2 weeks by oral gavage. All samples were examined via hematoxylin & eosin (H&E), histomorphometry of serous acinar surface areas, transmission electron microscopy (TEM), and blood analysis of malondialdehyde (MDA) and interleukin (IL-1β) levels.</p><p><strong>Results: </strong>Serum levels of both MDA and IL-1β were significantly greater in study I than in control and study II groups. Histologic examination revealed structural changes in serous acini and ducts of study I, with great preservation of the normal appearance of the acini and ducts in study II. Histomorphometry revealed a significant difference between control and study I, with no significant difference from that in study II. TEM revealed multiple ultrastructural changes in acinar cells and ducts of study I compared with those of study II, which maintained their normal features.</p><p><strong>Conclusions: </strong>Vitamin E plays crucial antioxidant and anti-inflammatory roles in counteracting the cytotoxic effects of TiO₂NPs by alleviating their deleterious impact on salivary glands.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"1342"},"PeriodicalIF":3.1,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12366081/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144942176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the relationship between periodontal bone loss and Schneiderian membrane thickness in upper posterior teeth with root tips associated with the maxillary sinus: a retrospective cone beam computed tomography study.","authors":"Kevser Sökmen, Nurullah Sökmen","doi":"10.1186/s12903-025-06684-x","DOIUrl":"https://doi.org/10.1186/s12903-025-06684-x","url":null,"abstract":"","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"1340"},"PeriodicalIF":3.1,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12366344/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144942068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}