BMC Oral HealthPub Date : 2025-05-05DOI: 10.1186/s12903-025-05918-2
Abd Elsalam Awad Ali, Ahmed Habib, Mohamed Shady
{"title":"Digital versus conventional techniques for construction of mandibular implant retained overdenture.","authors":"Abd Elsalam Awad Ali, Ahmed Habib, Mohamed Shady","doi":"10.1186/s12903-025-05918-2","DOIUrl":"https://doi.org/10.1186/s12903-025-05918-2","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to evaluate two different construction techniques (conventional and 3D-printed techniques) for two implant-retained complete mandibular overdentures regarding mechanical wear of the occlusal surface using 3D digital analysis and occlusion force distribution using the digital occlusal analysis system (Occlusense).</p><p><strong>Methods: </strong>Twenty patients were selected for this study from the prosthetic department, Faculty of Dentistry, Mansoura University. Each patient received two implants in the mandibular canine areas with locator attachments to retain the overdentures. According to the overdenture construction technique, all patients were randomly divided into two equal groups: the conventional heat polymerized overdenture group and the 3D-printed overdenture group. The mandibular overdentures were compared and evaluated immediately and after 12 months of insertion regarding mechanical wear of the occlusal surface using 3D digital analysis and occlusal force distribution using a digital occlusal analysis system (Occlusense).</p><p><strong>Results: </strong>3d printed group showed significantly higher occlusal surface wear than conventional group after twelve months (T12) with a p value ≤ 0.05. 3d printed group showed significantly more occlusal force distribution than conventional group with a p value ≤ 0.05. Also, there was a significant difference in occlusal force distribution with advance of time for each group, with a p value ≤ 0.05 level of significance.</p><p><strong>Conclusion: </strong>Within the limitations of this study, it was shown that implant overdentures constructed by 3D-printing techniques offer a promising results in distribution of occlusal forces for achieving occlusal equilibration. However, in term of wear resistance more developments need to be done to improve material properties.</p><p><strong>Trial registration: </strong>The study was approved by the local ethical committee of the Faculty of Dentistry, Mansoura University (No. A02060922) (6/9/2022) and retrospectively registered at ClinicalTrials.gov (ClinicalTrials.gov Identifier NCT06139003) (16/11/2023).</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"686"},"PeriodicalIF":2.6,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12054292/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143967308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC Oral HealthPub Date : 2025-05-03DOI: 10.1186/s12903-025-06030-1
Wei Wang, Changjie Xiao, Siyi Li, Min Li, Fuju Zheng, Luxiang Shang, Rui Li
{"title":"Oral health literacy and behaviors among Chinese university students: a comparative study of medical and non-medical students.","authors":"Wei Wang, Changjie Xiao, Siyi Li, Min Li, Fuju Zheng, Luxiang Shang, Rui Li","doi":"10.1186/s12903-025-06030-1","DOIUrl":"https://doi.org/10.1186/s12903-025-06030-1","url":null,"abstract":"<p><strong>Background: </strong>Oral health literacy (OHL) plays a crucial role in improving oral health outcomes. Due to their academic background, medical students are presumed to have higher OHL levels than students in other disciplines. However, few studies have directly compared OHL and oral health behaviors between medical and non-medical students.</p><p><strong>Methods: </strong>This cross-sectional study recruited undergraduate students from seven universities in Shandong, China. A total of 2,695 students completed an online survey between August and September 2024. The questionnaire collected information on demographic characteristics, OHL, and oral health-related behaviors. OHL was measured using the validated Chinese version of the short-form Dental Health Literacy Scale (HeLD-14). Data were analyzed using t-tests, chi-square tests, and mediation analysis conducted with the PROCESS macro in SPSS.</p><p><strong>Results: </strong>Among the participants, 1,572 (58.3%) were medical students. Medical students scored significantly higher on the HeLD-14 total score than non-medical students (56.96 ± 11.04 vs. 54.59 ± 11.24, P < 0.001), with consistently higher scores across all dimensions. In terms of oral health behaviors, medical students were more likely to brush after late-night snacks, use fluoride toothpaste, and floss regularly compared to non-medical students (all P < 0.05). Mediation analysis showed that OHL partially mediated the relationship between academic major and these oral health behaviors.</p><p><strong>Conclusion: </strong>Medical students exhibit higher OHL and healthier oral health behaviors compared to non-medical students. Enhancing OHL among non-medical students may foster better oral health behaviors and improve overall oral health outcomes.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"683"},"PeriodicalIF":2.6,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12049789/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143977687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC Oral HealthPub Date : 2025-05-03DOI: 10.1186/s12903-025-06061-8
Maria Cristina Faria-Teixeira, Francisco Azevedo-Coutinho, Ângelo David Serrano, Rosa María Yáñez-Vico, Francisco Salvado E Silva, António Vaz-Carneiro, Alejandro Iglesias-Linares
{"title":"Correction: Orthognathic surgery-related condylar resorption in patients with skeletal class III malocclusion versus class II malocclusion: a systematic review and meta-analysis.","authors":"Maria Cristina Faria-Teixeira, Francisco Azevedo-Coutinho, Ângelo David Serrano, Rosa María Yáñez-Vico, Francisco Salvado E Silva, António Vaz-Carneiro, Alejandro Iglesias-Linares","doi":"10.1186/s12903-025-06061-8","DOIUrl":"https://doi.org/10.1186/s12903-025-06061-8","url":null,"abstract":"","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"682"},"PeriodicalIF":2.6,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12049800/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143962969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC Oral HealthPub Date : 2025-05-02DOI: 10.1186/s12903-025-06049-4
Bilge Cansu Uzun Saylan, Büşra Yılmaz, Veli Özgen Öztürk, Harika Atmaca, Gülnur Emingil
{"title":"Evaluation of annexin A1, carbonic anhydrase 1, and elongation factor 1-gamma levels in periodontal diseases.","authors":"Bilge Cansu Uzun Saylan, Büşra Yılmaz, Veli Özgen Öztürk, Harika Atmaca, Gülnur Emingil","doi":"10.1186/s12903-025-06049-4","DOIUrl":"https://doi.org/10.1186/s12903-025-06049-4","url":null,"abstract":"<p><strong>Background: </strong>Periodontitis arises from dysbiotic subgingival microbiota and an unresolved inflammatory response. Annexin A1 (ANXA1), Carbonic Anhydrase I (CA1), and Elongation Factor 1-gamma (EF1-Ɣ) may play a role in periodontal inflammation and disease pathogenesis. This study aimed to investigate the levels of these molecules in gingival crevicular fluid (GCF) of individuals with different periodontal conditions.</p><p><strong>Methods: </strong>GCF samples were collected from 20 patients with Stage III Grade B periodontitis, 20 with Stage III Grade C periodontitis, 19 gingivitis patients, and 21 periodontally healthy individuals. ANXA1, CA1, and EF1-Ɣ levels were measured using ELISA.</p><p><strong>Results: </strong>Clinical parameters were significantly higher in periodontitis groups compared to gingivitis and healthy groups (p < 0.001). GCF EF1-Ɣ total amount differed among groups, with higher levels in gingivitis compared to periodontitis and healthy control groups (p < 0.001). Elevated levels of EF1-Ɣ were found in gingivitis compared to Stage III/B and Stage III/C periodontitis (p < 0.001). GCF ANXA1 and CA1 levels were similar across study groups (p > 0.05).</p><p><strong>Conclusion: </strong>Within the limitations of this study, it might be suggested that the decreased levels of EF1-Ɣ in diseased sites of periodontitis and its elevated levels in gingivitis are associated with the pathogenesis of periodontal disease.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"676"},"PeriodicalIF":2.6,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12046864/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143960844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC Oral HealthPub Date : 2025-05-02DOI: 10.1186/s12903-025-06048-5
Rieke Scharbrodt, Sarah Habig, Michael Kalab, Eva Baumann, Lisa Felgendreff, Astrid Dempfle, Katrin Hertrampf
{"title":"Knowledge level of diagnostic procedures and risk factors for oral cancer among oral healthcare providers in Germany.","authors":"Rieke Scharbrodt, Sarah Habig, Michael Kalab, Eva Baumann, Lisa Felgendreff, Astrid Dempfle, Katrin Hertrampf","doi":"10.1186/s12903-025-06048-5","DOIUrl":"https://doi.org/10.1186/s12903-025-06048-5","url":null,"abstract":"<p><strong>Background: </strong>Oral cancer is an underestimated and growing public health problem. The majority of cases are diagnosed at a late stage, even though oral cancer can be detected early by routine visual and tactile examination. Dental healthcare providers thus play a vital role in its early detection. This study assessed dental healthcare providers' knowledge of diagnostic procedures and risk factors for oral cancer.</p><p><strong>Methods: </strong>A cross-sectional, observational study was conducted using a validated survey of 38 items focusing on knowledge of diagnostic procedures and risk factors, and questions on continuing education. From October to December 2023, the online survey invitation was sent via all German state Dental Associations to their members. Participants' socio-demographic data and responses in the \"knowledge, opinion and continuing education\" section were analysed descriptively. Linear regressions assessed the associations between participants' characteristics or opinions and their knowledge of oral cancer (knowledge score).</p><p><strong>Results: </strong>Overall, 8,132 participants began the survey. After filtering for reliability and completeness, data from 3,458, 3,472, and 2,933 participants were available for \"socio-demographics\", \"knowledge\", and \"opinions and continuing education\", respectively. Most participants were women (60%), between 30 to 49 years old (48%). The majority knew the most common type of oral cancer and the most common lesions associated with it. Furthermore, almost 89% of the participants were aware that early detection improves survival rates. The main risk factors (tobacco, alcohol, prior oral cancer) were well known. However, the potential for improvement in knowledge of localisation, signs, stage of diagnosis and the specific age group at risk was noted. Fewer years in the dental profession and since attending the last continuing education course were associated with higher levels of knowledge.</p><p><strong>Conclusions: </strong>Knowledge of localisation, signs, stage of diagnosis, and specific risk groups can be improved. These topics should thus be integral to the dental curriculum and addressed through structured continuing education programmes, as the study's results suggest that knowledge declines over time without continuing education.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"681"},"PeriodicalIF":2.6,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12048965/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143963802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Macrophage is crucial for tongue development by regulating myogenesis and vascularization.","authors":"Ziyao Wang, Mengqiao Wang, Jiani Liu, Delu Zhao, Jixiao Wang, Fulan Wei","doi":"10.1186/s12903-025-06059-2","DOIUrl":"https://doi.org/10.1186/s12903-025-06059-2","url":null,"abstract":"<p><strong>Background: </strong>Abnormal tongue development is a craniofacial deformity that affects dental-maxillofacial esthetics and function. Recent evidence has identified macrophages as multi-functional immune cells crucial for heart and brain development. However, it is still unknown whether macrophages affect tongue development. Therefore, this study aims to assess the distribution, phenotype, and roles of macrophages in the developing tongue.</p><p><strong>Methods: </strong>In this study, immunohistochemical (IHC) and multiplex immunofluorescence (mIF) staining were conducted on C57BL/6 mice at embryonic day (E) 13.5, E14.5, E16.5, and E18.5 to analyze the distribution and phenotype of macrophages. Hematoxylin-Eosin (HE), IHC, IF, and mIF staining were also performed on embryonic CX3 CR1-CreERT2; Rosa-DTA conditional macrophage-depleted mice to investigate the effects on fetal tongue development and elucidate mechanisms from myogenesis, vascularization, and cell apoptosis. Statistical significance between the two groups was determined using unpaired two-tailed Student's t-tests. For comparisons involving three or more groups, one-way analysis of variance (ANOVA) followed by Tukey's multiple comparison tests was utilized. A significance level of P < 0.05 was set for statistical significance.</p><p><strong>Results: </strong>Macrophages were present in the developing tongue from E13.5 to E18.5, with a majority being of the M2 phenotype. Depletion of macrophages resulted in abnormal tongue morphology, decreased tongue height, width, and size, as well as reduced and disorganized muscle fibers. Depletion of macrophages also increased apoptosis. Vascular morphogenesis was impacted, with reductions in the luminal and vascular wall cross-sectional areas of the lingual artery. Vascular endothelial cells were reduced and disorganized with decreased expression of VEGFA and TGF-β1. Moreover, macrophages were located near vascular endothelial cells and secreted pro-angiogenic factors, suggesting their involvement in promoting vascularization.</p><p><strong>Conclusions: </strong>Our findings indicate that macrophages play crucial roles in fetal tongue development by affecting myogenesis, cell apoptosis, and vascular growth.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"678"},"PeriodicalIF":2.6,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12049047/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144062049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC Oral HealthPub Date : 2025-05-02DOI: 10.1186/s12903-025-06053-8
Sevgi Arabulan, Rüştü Özant Önçağ, Zeliha Aslı Öcek
{"title":"Access to oral healthcare for children during the COVID-19 pandemic: a mixed-methods study in the Aegean region of Türkiye.","authors":"Sevgi Arabulan, Rüştü Özant Önçağ, Zeliha Aslı Öcek","doi":"10.1186/s12903-025-06053-8","DOIUrl":"https://doi.org/10.1186/s12903-025-06053-8","url":null,"abstract":"<p><strong>Background: </strong>The COVID-19 pandemic significantly disrupted healthcare systems, particularly affecting vulnerable populations such as children and individuals with special needs, causing delays and reductions in routine dental services. The aim of this study was to evaluate level of access and identify determinants of access to oral healthcare for children aged 0-13 during COVID-19 restrictions.</p><p><strong>Methods: </strong>Mixed-methods research design was adopted. This cross-sectional study included 270 children aged 0 to 13 years who visited Ege University Pediatric Dental Clinics between August 2021 and February 2022. Interviewer-administered questionnaires collected information about sociodemographic and economic characteristics, as well as dental service utilization during the pandemic. \"Access\" to receive oral health care to address existing dental problems is defined separately for each application to the institution. Statistical analyses were conducted using IBM SPSS Statistics 23, with Pearson's Chi-Square, Fisher's Exact, and Binary Logistic Regression tests applied to examine variable relationships. A 95% confidence interval and a significance level of p < 0.05 were adopted, with model fit assessed using the Hosmer-Lemeshow test and Nagelkerke R². Qualitative data from 16 in-depth interviews were analysed using thematic analysis to explore the barriers to accessing oral healthcare during the COVID-19 pandemic.</p><p><strong>Results: </strong>During the pandemic, 62.3% of dental institutions' applications had limited access to care. Parental education, employment status, and household income significantly affected access (p < 0.005). Multiple logistic regression revealed that applying to university clinics (OR = 4.78; 95% CI 2.24-10.21) and private institutions (OR = 4.33; 95% CI 2.30-8.17) led to higher access rates when compared to public dental centres. The father's regular employment (OR = 3.39; 95% CI 1.37-8.34) and the child's previous dental contacts (OR = 2.37; 95% CI 1.21-4.62) increased the likelihood of accessing oral healthcare. The risk of contracting infections and income loss were pandemic related barriers. The most common barriers were those concerning the availability of services at public dental clinics. Children with disabilities faced further barriers due to the risk of infection, difficulty reaching institutions, and unmet dental needs for treatment under general anaesthesia.</p><p><strong>Conclusion: </strong>Higher socioeconomic status and past contact with dentists had a positive effect on oral healthcare access. Dental services provided by public institutions had a lower level of access. The COVID-19 pandemic highlighted oral healthcare inequalities, particularly for those children with disabilities in Türkiye. Policymakers should strengthen public health crisis plans in order to improve children's oral healthcare access.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"680"},"PeriodicalIF":2.6,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12048938/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143965122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC Oral HealthPub Date : 2025-05-02DOI: 10.1186/s12903-025-06042-x
Ping-Chen Chung, Ta-Chien Chan
{"title":"Use of serum albumin levels and salivary biomarkers in assessing periodontal disease: a community hospital perspective.","authors":"Ping-Chen Chung, Ta-Chien Chan","doi":"10.1186/s12903-025-06042-x","DOIUrl":"https://doi.org/10.1186/s12903-025-06042-x","url":null,"abstract":"<p><strong>Background: </strong>Periodontal status can be reflected in serum and oral biomarkers. Salivary biomarkers are novel screening tools for individuals with dentophobia or disabilities. This study aimed to explore the differences in SiLL-Ha results and serum albumin levels between clinical attachment loss (CAL) ≥ 5 mm (Group A) and CAL < 5 mm (Group B) as well as the influence of sex on these differences.</p><p><strong>Methods: </strong>This study recruited healthy adults aged 35-80 years from a community hospital. Participants completed a demographic questionnaire. We collected the participants' medical history, including hypertension, diabetes mellitus (DM) and hyperlipidemia, from electronically stored medical records. Additionally, they underwent a collaborated saliva test, an oral examination including records of clinical attachment levels, and a blood test to measure albumin levels sequentially. Participants were divided into Group A and Group B based on a CAL cut-off point of 5 mm. Multivariable logistic regression was used to analyze associations between the SiLL-Ha results, serum albumin levels, periodontitis, and sex stratification.</p><p><strong>Results: </strong>The mean age of the 231 participants was 64.4 years, and 58.4% were women. Older age, low serum albumin levels, and high blood levels of SiLL-Ha were associated with periodontitis. Among the women, age and blood level of SiLL-Ha output were significantly associated with periodontitis. Among men, serum albumin level was significantly associated with periodontitis. Participants with DM were less likely to have periodontitis, particularly females.</p><p><strong>Conclusions: </strong>The saliva test is a noninvasive tool applicable not only in dental clinics but also in community settings. It is beneficial for self-monitoring of oral health and promoting health awareness and behavior.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"679"},"PeriodicalIF":2.6,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12048980/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143970625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy and tolerability of probiotics, prebiotics, and symbiotics consumption on oral complications of patients with thyroid and head and neck cancers: a systematic review and meta-analysis.","authors":"Mohammadreza Shafiei, Shayan Mardi, Soodeh Ghadimi, Helia Poorshahbazi, Roozbeh Pourabbas, Mohammadamin Keykhah, Hosein Rafiemanesh","doi":"10.1186/s12903-025-05876-9","DOIUrl":"https://doi.org/10.1186/s12903-025-05876-9","url":null,"abstract":"<p><strong>Background: </strong>Oral complications following cancer treatment are a challenging issue for oncologists. Several studies have demonstrated the efficacy of biotics in the prevention and treatment of oral complications in thyroid and head and neck cancers.</p><p><strong>Methods: </strong>Following the PRISMA criteria, a systematic review and meta-analysis of included studies on efficacy, safety, dosage, and duration of treatment was performed.</p><p><strong>Results: </strong>A total of 12 randomized controlled trials and a total of 885 individuals were included in this meta-analysis. Our analysis showed that biotics had a slight but insignificant effect on the incidence of oral mucositis (Risk ratio (RR) = 0.90, 95% CI [0.79, 1.03]), and a significant impact on reducing the severity of oral mucositis (RR = 0.62, 95% CI [0.48, 0.80]). Biotics also had a slight but insignificant effect in developing xerostomia in thyroid and Head and neck cancer (HNC) patients. Subgroup meta-analysis demonstrated that Bifidobacterium-containing products were more effective than other blends.</p><p><strong>Conclusion: </strong>Our findings demonstrated that biotics are effective and safe for HNC and thyroid patients suffering from oral complications.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"677"},"PeriodicalIF":2.6,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12049045/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143969962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Successful interdisciplinary retreatment after initial treatment failure in a cleft lip adolescent.","authors":"Yuhua Jiao, Yongwei Tao, Wenzhi Du, Chunhui Zhu, Zhanping Ren, Yuxia Hou, Huaxiang Zhao","doi":"10.1186/s12903-025-06055-6","DOIUrl":"https://doi.org/10.1186/s12903-025-06055-6","url":null,"abstract":"<p><strong>Background: </strong>Cleft lip and/or palate (CL/P) is the most common craniofacial birth defect. Patients with CL/P typically exhibit severe malocclusions in the transverse, vertical, and sagittal directions, and often have poor oral hygiene. Due to the complex nature of the disease, the dental treatment for CL/P patients presents considerable challenges, sometimes resulting in interrupted treatments and subsequent treatment failures.</p><p><strong>Case presentation: </strong>Here, we present an interdisciplinary retreatment for an adolescent with unilateral complete cleft lip (UCCL), who initially received an orthodontic treatment elsewhere but faced issues such as poor oral hygiene, deep overbite of anterior teeth, significant discrepancies in the width of posterior teeth, and persistent spaces resulting from the alveolar cleft. Throughout the retreatment, we employed tooth remineralization accompanied by strict oral hygiene instructions, various skilled orthodontic techniques, surgical interventions, and aesthetic prosthodontic work. The adolescent showed dramatic improvements in facial and dental aesthetics, as well as in dental occlusion and function after treatment.</p><p><strong>Conclusions: </strong>In summary, this case report emphasizes the critical role of effective oral hygiene management and interdisciplinary teamwork among dental subspecialties in the treatment of CL/P patients.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"675"},"PeriodicalIF":2.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12044786/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143970183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}