BMC Public HealthPub Date : 2025-02-27DOI: 10.1186/s12889-025-21915-0
Bowen Zhang, Weijia Liu, Jingrui Wang, Lulu Zhang, Ke Wang, Peixi Wang
{"title":"Sleep duration, daytime napping and the risk of incident metabolic syndrome vary by age and sex: findings from the China health and retirement longitudinal study.","authors":"Bowen Zhang, Weijia Liu, Jingrui Wang, Lulu Zhang, Ke Wang, Peixi Wang","doi":"10.1186/s12889-025-21915-0","DOIUrl":"10.1186/s12889-025-21915-0","url":null,"abstract":"<p><strong>Objective: </strong>Currently, the association of sleep duration and daytime napping with the prevalence of metabolic syndrome (MetS) is still controversial. This study was designed to explore the association between sleep duration, daytime napping and MetS by age and sex in Chinese adults.</p><p><strong>Methods: </strong>Data were obtained from the 2011 and 2015 waves of the China Health and Retirement Longitudinal Study (CHARLS). Participants with MetS at baseline or with missing data were excluded, leaving 2803 participants (≥ 45 years old) who completed follow-up and were included in the longitudinal analysis. Sleep duration and daytime napping were determined by self-reported questionnaires. Medical conditions, including MetS, dyslipidaemia, hypertension, and diabetes mellitus, were determined from a fasting blood specimen and physical exam at the baseline visit. Logistic regression models were performed to explore the longitudinal associations of baseline napping and sleep duration with MetS and its occurrence.</p><p><strong>Results: </strong>During a median follow-up period of 4 years, 616 participants (22.0%) developed new-onset MetS. Compared with non-napping, longer daytime napping (> 30 min/day) was significantly associated with the occurrence of MetS (OR: 1.247, 95% CI: 1.001, 1.554), and a significant association was still present after adjustment for each of the covariates. In the subgroup analysis, longer daytime napping (> 30 min/day) was also significantly associated with MetS in elderly females (OR: 1.946, 95% CI: 1.226, 3.090). Moreover, sleep duration was not significantly associated with MetS in our study.</p><p><strong>Conclusion: </strong>A longer napping duration is associated with an increased risk of MetS in an older Chinese population, and this association differed according to sex.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":"25 1","pages":"803"},"PeriodicalIF":3.5,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11869476/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143522638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC Public HealthPub Date : 2025-02-27DOI: 10.1186/s12889-025-21996-x
Rebecca A Dennison, Reanna J Clune, Joanna Tung, Stephen D John, Sowmiya A Moorthie, Jo Waller, Juliet A Usher-Smith
{"title":"Societal views on using risk-based innovations to inform cancer screening and referral policies: findings from three community juries.","authors":"Rebecca A Dennison, Reanna J Clune, Joanna Tung, Stephen D John, Sowmiya A Moorthie, Jo Waller, Juliet A Usher-Smith","doi":"10.1186/s12889-025-21996-x","DOIUrl":"10.1186/s12889-025-21996-x","url":null,"abstract":"<p><strong>Background: </strong>Recent advances mean that innovations are emerging that enable better stratification of individuals based on their risk of cancer so that screening or diagnostic investigations can be targeted to those at greatest need. We explored the views of the public, from a societal perspective, of using such risk-based innovations to identify people's cancer risk and allocating healthcare accordingly.</p><p><strong>Methods: </strong>We conducted three community juries, each with 7-9 participants. Participants were informed about the topic and potential novel risk-based innovations through a series of presentations from experts and discussions. Polygenic risk scores, geodemographic segmentation, continuous monitoring of biomarkers, minimally invasive tests, artificial intelligence analysis of medical records, and wearable devices were used as examples. The participants then deliberated over the research questions before reporting their verdicts on the acceptability of these novel data-based approaches in principle. Transcripts were analysed using codebook thematic analysis.</p><p><strong>Results: </strong>All juries found that the proposed risk-based approaches to cancer healthcare were, in general, acceptable. Primarily this was because the approaches would enable use of information in a positive and constructive way. However, there were a number of qualifiers or caveats. In particular, participants highlighted the necessity of using accurate and robust data with a well-evidenced association with cancer risk. They also expressed concerns about unintended consequences such as for insurance, scams or erosion of personal liberty, and the burden to participate in data collection across society. All agreed that opting-out must be straightforward.</p><p><strong>Conclusions: </strong>Informed members of the public supported the concept of using innovations to estimate cancer risk and inform healthcare. Their priorities for accuracy, data security, participation burden, and personal liberty and choice tended to overlap with those of developers and policymakers. Work to ready these innovations for implementation should continue, with the public's priorities accounted for in their development and dissemination in order to address any unintended consequences upfront.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":"25 1","pages":"801"},"PeriodicalIF":3.5,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11869612/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143522643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC Public HealthPub Date : 2025-02-27DOI: 10.1186/s12889-025-21748-x
Huiqin Zhong, Ya Shao, Xin Chen, Na Wang, Yan Zhan, Boxiong Gong, Rong Zhang, Longti Li
{"title":"Associations of composite dietary antioxidant index with premature death and all-cause mortality: a cohort study.","authors":"Huiqin Zhong, Ya Shao, Xin Chen, Na Wang, Yan Zhan, Boxiong Gong, Rong Zhang, Longti Li","doi":"10.1186/s12889-025-21748-x","DOIUrl":"10.1186/s12889-025-21748-x","url":null,"abstract":"<p><p>Although previous evidence indicates that the composite dietary antioxidant index (CDAI) is negatively associated with health outcomes, no studies have explored the association between CDAI and premature death. This research utilized a cohort study design with 37,301 participants from the National Health and Nutrition Examination Survey (NHANES) from 2003 to 2018. Cox proportional hazard regression was employed to analyze the association between CDAI and premature death and all-cause mortality. Restricted cubic spline (RCS) analysis was performed to examine the nonlinear relationship between variables, and Kaplan-Meier analysis was used to evaluate survival outcomes over time. Sensitivity and subgroup analyses were conducted to assess the reliability of the findings. During a median follow-up period of 8.25 years, 4487 deaths were recorded, with 1671 classified as premature. The study revealed a negative correlation between CDAI and premature death (Per-SD hazard ratio [HR] 0.91, 95% CI 0.85-0.97; quartiles [Q4:Q1] HR 0.83, 95% CI: 0.70, 0.98) as well as all-cause mortality (Per-SD HR 0.96, 95% CI 0.92-1.00; quartiles [Q4:Q1] HR 0.91, 95%CI: 0.82, 1.01). The RCS analyses indicated a 'U' shaped relationship between CDAI and premature death and all-cause mortality. The threshold effect analysis pinpointed the inflection points for CDAI relative to premature death and all-cause mortality at 1.42 and 1.48, respectively. Kaplan-Meier curves illustrated that the likelihood of individual survival increases with higher CDAI quartiles. The results highlight the significance of dietary antioxidant intake in enhancing extending lifespan. Further research is needed to investigate the underlying mechanisms and determine optimal intake levels for improving health outcomes.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":"25 1","pages":"796"},"PeriodicalIF":3.5,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11866784/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143522528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC Public HealthPub Date : 2025-02-27DOI: 10.1186/s12889-025-21832-2
Ke Pu, Ting Luo, Juan Li, Qian Tang, Yang Feng, Guodong Yang
{"title":"Periodontitis and gastrointestinal cancer: a nationwide cohort study of NHANES 2009-2014.","authors":"Ke Pu, Ting Luo, Juan Li, Qian Tang, Yang Feng, Guodong Yang","doi":"10.1186/s12889-025-21832-2","DOIUrl":"10.1186/s12889-025-21832-2","url":null,"abstract":"<p><p>The association between periodontitis and gastrointestinal tract (GIT) cancer has undergone extensive investigation. However, there is ongoing controversy regarding the impact of periodontitis on the incidence and mortality rates among GIT cancer patients. This study aims to clarify the relationship between periodontitis and the risk as well as mortality rates of GIT cancer.</p><p><strong>Methods: </strong>The data utilized in this study were obtained from the National Health and Nutrition Examination Survey (NHANES) database for the years 2009-2014, which included a total of 10,706 participants from the United States. The incidence and mortality rates of GIT cancer were analyzed in relation to periodontitis. To ensure the reliability of the results, additional adjustments for covariates and stratification analyses were conducted.</p><p><strong>Results: </strong>In the multivariate logistic regression analysis, various variables such as age, sex, race, BMI, income, education, smoking, alcohol consumption, hypertension, hyperlipidemia, and diabetes mellitus were adjusted for. The analysis revealed no positive association between periodontitis and an increased risk of total cancer or GIT cancer including colorectal cancer. However, periodontitis was found to be significantly associated with higher mortality rates among participants for all-cause (HR: 1.58; 95% CI: 1.26-2.00; P < 0.001), GIT cancer (HR: 1.65; 95% CI: 1.24-2.20; P < 0.001), and colorectal cancer (HR: 1.65; 95% CI: 1.24-2.19; P < 0.001) individually.</p><p><strong>Conclusions: </strong>The study demonstrates that periodontitis is not associated with an increased risk of incidence for total cancer, or GIT cancer including colorectal cancer. However, it is significantly associated with a higher risk of mortality for all-cause, GIT cancer, and colorectal cancer among participants in the NHANES study.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":"25 1","pages":"804"},"PeriodicalIF":3.5,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11869642/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143522540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC Public HealthPub Date : 2025-02-27DOI: 10.1186/s12889-025-22062-2
Federica Asta, Valentina Minardi, Benedetta Contoli, Valentina Possenti, Virginia Casigliani, Maria Masocco
{"title":"Did the pandemic change lifestyle behaviours in Italy? An interrupted time series analysis on the four main NCDs behavioural risk factors from 2008 to 2023.","authors":"Federica Asta, Valentina Minardi, Benedetta Contoli, Valentina Possenti, Virginia Casigliani, Maria Masocco","doi":"10.1186/s12889-025-22062-2","DOIUrl":"10.1186/s12889-025-22062-2","url":null,"abstract":"<p><strong>Background: </strong>The COVID-19 pandemic has had repercussions in several areas. The indirect effects of the pandemic on healthy living behaviours are multiple and complex to assess. The aim is to assess the impact of the outbreak of COVID-19 pandemic in Italy on the most relevant modifiable behaviours risks for non-communicable diseases (NCDs).</p><p><strong>Methods: </strong>PASSI 2008-2023 data referring to a sample of 18-69-year-olds residing in Italy was used to estimate the prevalences of smoking, alcohol, fruit and vegetable consumption, and physical inactivity lifestyle. For each of these risks was used an interrupted time series (ITS) study with Generalized Least Squares (GLS) model to assess trends before and after the pandemic's outbreak in Italy (March 2020). The \"intervention\" period is postulated as March 2020, and the \"post-intervention\" period extends from April 2020 to December 2023. In these models, the hypothetical situation without \"intervention\" and with the trend remains unchanged is commonly known as the 'counterfactual' scenario. Through ITS model both \"counterfactual data\" and \"factual data\" were obtained.</p><p><strong>Results: </strong>From 2008 to 2023, 532,115 people were interviewed. Results showed, during \"post-intervention\" period, significant differences between factual and counterfactual prevalences started in 2022 and strengthened during 2023 and for all of the four behavioural indicators analysed: smoking, high-risk alcohol consumption, fruit and vegetable consumption (both all three of them worsening) and physical inactivity (which appears to decrease). Current smokers exhibited similar prevalences in March 2020 (24.5% vs. 24.3%), followed by a plateau throughout the entire 'post-intervention' period. By December 2023, however, the counterfactual prevalence was significantly lower than the observed rate (24.5% factual vs. 22.7% counterfactual). The initial improvement observed in the prevalence of high-risk drinkers in March 2020 (13% factual vs. 17% counterfactual) was followed by a rapid worsening and in December 2023 the prevalence was significantly higher than expected (19.7% vs. 16.9%). The fruit and vegetable consumption worsened and the factual prevalence of five-a-day in December 2023 was significantly lower than counterfactual (6.6% vs. 9.0%). Physical inactivity following an initial worsening in March 2020 (albeit not statistically significant), appeared to decrease in December 2023, with the factual prevalence lower than counterfactual (26.9% vs. 32.4%).</p><p><strong>Conclusions: </strong>Results found in this article showed at the end of studied period the achievement of a plateau for current smokers, a worsening in the high-risk alcohol consumption, in fruit and vegetable intakes and a reduction in physical inactivity. Understanding shifts in these lifestyle indicators is crucial for the proper design of interventions aimed at reducing the burden of NCDs.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":"25 1","pages":"799"},"PeriodicalIF":3.5,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11869655/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143522460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correlations between family characteristics and childcare in optimizing the growth of children under six years.","authors":"Laili Rahayuwati, Desy Indra Yani, Sri Hendrawati, Arlette Suzy Setiawan, Damar Irza, Sherllina Rizqi Fauziah","doi":"10.1186/s12889-025-21931-0","DOIUrl":"10.1186/s12889-025-21931-0","url":null,"abstract":"<p><strong>Background: </strong>Families have a the primary influence on children. In particular, excellent childcare in the family is assumed to correlate with children's health status, growth, and development. Hence, some family factors contribute to the optimization of childcare. This study aims to analyze family characteristics that correlate with childcare for children under six in Indonesia.</p><p><strong>Methods: </strong>The data collection instrument used was a Performance and Accountability Survey Program (SKAP) questionnaire of the National Population and Family Planning Board for Indonesia to assess family function in children's health development in a sample of 7,651 parents, mothers, and/or fathers of children under six years of age. Childcare was the outcome variable. In addition, the chi-square test and logistic regression were used for statistical analysis.</p><p><strong>Results: </strong>The results showed a significant correlation between parents' education, family health insurance ownership, number of toddlers, preschool age children and media exposure to health with family parenting patterns that influence children's health. Meanwhile, parental age and parents occupation did not significantly contribute to childcare quality. Multivariate analysis showed that older age (particularly 20-34 years), exposure to media about health, family without health insurance, and parents with more than two toddlers and pre-school age were associated with better childcare.</p><p><strong>Conclusions: </strong>Several family characteristics were significantly associated with childcare for children under six, including health media exposure, older parental age (particularly 20-34 years), do not have family health insurance and have more than two toddlers and pre-school age children. These things contribute to the fulfilment of nutrition and exclusive breastfeeding, parenting patterns, and providing access to health services for children in the family.</p><p><strong>Ethics application number: </strong>The data were approved by the National Population and Family Planning Board for Indonesia Ethical Review Institutions number 454/LB.02/H4/2019.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":"25 1","pages":"807"},"PeriodicalIF":3.5,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11869615/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143522532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC Public HealthPub Date : 2025-02-27DOI: 10.1186/s12889-025-21853-x
Julia R Nummelin, Jama J Brookes, Raegan A Bishop, Calandra G Whitted, Chiranjeev Dash, Laura M Koehly
{"title":"The families SHARE project: novel insights on recruiting and engaging Black men in a community-based genomic education program.","authors":"Julia R Nummelin, Jama J Brookes, Raegan A Bishop, Calandra G Whitted, Chiranjeev Dash, Laura M Koehly","doi":"10.1186/s12889-025-21853-x","DOIUrl":"10.1186/s12889-025-21853-x","url":null,"abstract":"<p><strong>Background: </strong>Black Americans are disproportionately affected by a number of common complex conditions, such as cancer. Genomic tools like Family Health History (FHH) can be useful in guiding screening and behavior based on a person's risk for these conditions. Factors such as family communication and societal norms can influence individuals' knowledge of their FHH. Men, particularly Black men, are less likely than women to know FHH. Further, there is limited understanding of Black men's participation in FHH dissemination, as they are often underrepresented in biomedical research. Understanding Black men's perceptions of FHH sharing may help guide effective recruitment and retention efforts in future genomic research providing an opportunity to investigate their lack of engagement in FHH conversations.</p><p><strong>Aims: </strong>The purpose of this paper was two-fold: (1) Detail methods that were effective in recruiting and retaining Black men in community-based genomic research interventions, and (2) Evaluate the factors influencing men's participation in FHH gathering and sharing.</p><p><strong>Methods: </strong>This one-year, mixed methods study combined qualitative community-based education programs (n = 12) and semi-structured interviews (n = 27), with quantitative survey assessing participant characteristics and sex differences (n = 50). Transcripts from the program were coded by separate study team members for themes and provided insights into study participants' perceptions about FHH and their involvement in gathering and disseminating this information within their family.</p><p><strong>Results: </strong>Challenges in recruiting and retaining Black men prompted the study team to pivot recruitment strategies, including partnering with community-based organizations focused on men's health, growing the research team to include Black men, adapting to potential participants' time constraints, and creating opportunities to build trust. A thematic analysis of community education sessions and interviews identified five themes, including social role expectations and perceived family disconnectedness, that provide insights into potential barriers to participation. Qualitative data from participants suggests that beliefs and perceptions about the roles Black men play in health discussions within the family may influence their involvement, while community programs were seen as encouraging men to engage in these conversations.</p><p><strong>Conclusion: </strong>These lessons learned provide valuable perspectives on potential barriers to participation, which may inform future strategies that aim to engage Black men in family-oriented community education programs and genomic research.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":"25 1","pages":"805"},"PeriodicalIF":3.5,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11869665/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143522649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Casual association between social determinants of health and sexual health literacy in reproductive-aged women: a WHO model analysis.","authors":"Fatemeh Vakili, Malihe Nasiri, Zeinab Hamzehgardeshi, Shayesteh Jahanfar, Zohreh Mahmoodi, Seideh Hanieh Alamolhoda","doi":"10.1186/s12889-025-21896-0","DOIUrl":"10.1186/s12889-025-21896-0","url":null,"abstract":"<p><strong>Introduction: </strong>Sexual health literacy is an important factor affecting sexual health, and social determinants of health significantly increasing health literacy. This study aimed to investigate the relationship between social determinants of health and sexual health literacy.</p><p><strong>Method: </strong>The present cross-sectional study was conducted on 600 married women of reproductive age referred to health centers in Tehran, Iran (2024). Questionnaires included demographic and obstetric details, Perceived Social Support, Socioeconomic Status, and Intimate Partner Violence. The statistical analysis was performed in SPSS-27, and the relationship model was examined using the path analysis method in LISREL-8.8.</p><p><strong>Results: </strong>According to the path analysis, sexual health literacy was directly affected by domestic violence (B = -0.12) and perceived social support (B = 0.39). It was also indirectly affected by socioeconomic status (B = 0.44) and spouse education (B = 0.48).</p><p><strong>Conclusion: </strong>The results showed that some factors influence sexual health literacy in women both directly and indirectly. Given the factors identified in the suggested model, it is advisable to utilize this model as a suitable framework for research, design, and execution of initiatives concerning sexual health literacy.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":"25 1","pages":"789"},"PeriodicalIF":3.5,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11863530/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143514221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analysis of risk factors for foot ulcers in diabetes patients with neurovascular complications.","authors":"Zibo Fan, Yue Liu, Hao Xie, Qinfeng Yang, Guangqing Zhang, Ping Zhang, Hong Ding","doi":"10.1186/s12889-025-21639-1","DOIUrl":"10.1186/s12889-025-21639-1","url":null,"abstract":"<p><strong>Background: </strong>Diabetic foot ulcers (DFU), characterized by open sores or wounds primarily occurring on the feet of diabetes patients, are a serious and highly morbid complication of long-standing diabetes, accounting for significant morbidity and mortality. These ulcers develop when diabetes damages both nerves and blood vessels, a combination known as neurovascular complications. Neurovascular disease is a well-established risk factor. While studies have extensively examined risk factors for DFU, few have specifically focused on patients with diabetic neurovascular disease. Therefore, we assess the prevalence and risk factors for DFU in diabetic patients with established neurovascular complications.</p><p><strong>Methods: </strong>This study analyzed data from 6722 patients with diabetic neurovascular disease aged over 18 years old from the Southern Medical University Nanfang Hospital (SMUNFH) database (2018-2023) and 2689 patients with the same condition and age range from the National Institutes of Health (NIH) Integrated Surveillance System (NIS) database (2017-2019). The incidence of DFU was determined using information from the NIS database and SMUNFH databases. A binary logistic regression model was employed to explore the risk factors for DFU.</p><p><strong>Results: </strong>The incidence of DFU among neurovascular disease patients was 13.4% at SMUNH and 25.9% in the NIS Asian population. Multiple regression analysis identified several factors associated with DFU in the SMUNH database, including diabetic retinopathy, diabetic nephropathy, osteomyelitis, coronary heart disease, tinea pedis (fungal foot infection), sepsis, ability to sense a 128 Hz tuning fork (both left and right sides), C-reactive protein (CRP) levels, and urinary albumin-to-creatinine ratio (ACR). Analysis of NIS data revealed that in the broader Asian population, peripheral vascular disorders and osteomyelitis were associated with DFU.</p><p><strong>Conclusion: </strong>The prevalence of DFU is higher in Asia than in China. Focusing on peripheral vascular disorders and osteomyelitis can effectively reduce the prevalence of DFU in the Asian population while addressing diabetic retinopathy, diabetic nephropathy, osteomyelitis, coronary heart disease, tinea pedis, ability to sense a 128 Hz tuning fork, CRP levels, and urinary ACR can be effective in China.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":"25 1","pages":"792"},"PeriodicalIF":3.5,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11866585/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143514216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC Public HealthPub Date : 2025-02-26DOI: 10.1186/s12889-025-22038-2
Carine Rostello, Céline Gramond, Sabyne Audignon, Isabelle Thaon, Patrick Brochard, Julia Benoist, Antoine Gislard, François Laurent, Christophe Paris, Pascal Andujar, Bénédicte Clin, Jean-Claude Pairon, Fleur Delva
{"title":"Occupational exposure to ultrafine particles and lung cancer in a population exposed to asbestos.","authors":"Carine Rostello, Céline Gramond, Sabyne Audignon, Isabelle Thaon, Patrick Brochard, Julia Benoist, Antoine Gislard, François Laurent, Christophe Paris, Pascal Andujar, Bénédicte Clin, Jean-Claude Pairon, Fleur Delva","doi":"10.1186/s12889-025-22038-2","DOIUrl":"10.1186/s12889-025-22038-2","url":null,"abstract":"<p><strong>Background: </strong>Ultrafine particles are present in ever greater quantities in the workplace and only one epidemiological study to date has found an association with the occurrence of lung cancer.</p><p><strong>Objective: </strong>To investigate the effect of occupational exposure to ultrafine particles on the risk of lung cancer.</p><p><strong>Methods: </strong>The ARDCO is a surveillance program involving retiree workers who had been exposed to asbestos during their working life. Exposure to ultrafine particles over the complete lifetime occupational history was assessed using the French job exposure matrix MATPUF. Cox proportional hazard models were used to estimate hazard ratios (HRs) and 95% confidence intervals (95% CI).</p><p><strong>Results: </strong>There was no association between exposure to ultrafine particles and lung cancer after adjustment for smoking and exposure to asbestos and crystalline silica.</p><p><strong>Conclusion: </strong>The findings do not indicate increased risks of lung cancer for UFP after adjustment for level of exposure to asbestos, crystalline silica, and smoking status.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":"25 1","pages":"784"},"PeriodicalIF":3.5,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11863659/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143514441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}