BJPsych Open最新文献

{"title":"Longitudinal changes in cardiac mIBG scintigraphy in mild cognitive impairment with Lewy bodies.","authors":"Gemma Greenfinch, Calum A Hamilton, Paul C Donaghy, Michael Firbank, Nicola A Barnett, Louise Allan, George S Petrides, John-Paul Taylor, John T O'Brien, Alan J Thomas","doi":"10.1192/bjo.2024.766","DOIUrl":"10.1192/bjo.2024.766","url":null,"abstract":"<p><p>The aim of this study was to determine whether there was a significant change in cardiac [123I]-metaiodobenzylguanidine uptake between baseline and follow-up in individuals with mild cognitive impairment with Lewy bodies (MCI-LB) who had normal baseline scans. Eight participants with a diagnosis of probable MCI-LB and a normal baseline scan consented to a follow-up scan between 2 and 4 years after baseline. All eight repeat scans remained normal; however, in three cases uptake decreased by more than 10%. The mean change in uptake between baseline and repeat was -5.2% (range: -23.8% to +7.0%). The interpolated mean annual change in uptake was -1.6%.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"10 6","pages":"e223"},"PeriodicalIF":3.9,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11698149/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142779333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lipid disturbances induced by psychotropic drugs: clinical and genetic predictors for early worsening of lipid levels and new-onset dyslipidaemia in Swiss psychiatric samples.","authors":"Aurélie Delacrétaz, Marie Sadler, Franziska Gamma, Martin Preisig, Hélène Richard-Lepouriel, Armin von Gunten, Philippe Conus, Kerstin Jessica Plessen, Zoltan Kutalik, Chin B Eap","doi":"10.1192/bjo.2024.757","DOIUrl":"10.1192/bjo.2024.757","url":null,"abstract":"<p><strong>Background: </strong>Early worsening of plasma lipid levels (EWL; ≥5% change after 1 month) induced by at-risk psychotropic treatments predicts considerable exacerbation of plasma lipid levels and/or dyslipidaemia development in the longer term.</p><p><strong>Aims: </strong>We aimed to determine which clinical and genetic risk factors could predict EWL.</p><p><strong>Method: </strong>Predictive values of baseline clinical characteristics and dyslipidaemia-associated single nucleotide polymorphisms (SNPs) on EWL were evaluated in a discovery sample (<i>n</i> = 177) and replicated in two samples from the same cohort (PsyMetab; <i>n</i>₁ = 176; <i>n</i>₂ = 86).</p><p><strong>Results: </strong>Low baseline levels of total cholesterol, low-density lipoprotein cholesterol (LDL-C) and triglycerides, and high baseline levels of high-density lipoprotein cholesterol (HDL-C), were risk factors for early increase in total cholesterol (<i>P</i> = 0.002), LDL-C (<i>P</i> = 0.02) and triglycerides (<i>P</i> = 0.0006), and early decrease in HDL-C (<i>P</i> = 0.04). Adding genetic parameters (<i>n</i> = 17, 18, 19 and 16 SNPs for total cholesterol, LDL-C, HDL-C and triglycerides, respectively) improved areas under the curve for early worsening of total cholesterol (from 0.66 to 0.91), LDL-C (from 0.62 to 0.87), triglycerides (from 0.73 to 0.92) and HDL-C (from 0.69 to 0.89) (<i>P</i> ≤ 0.00003 in discovery sample). The additive value of genetics to predict early worsening of LDL-C levels was confirmed in two replication samples (<i>P</i> ≤ 0.004). In the combined sample (<i>n</i> ≥ 203), adding genetics improved the prediction of new-onset dyslipidaemia for total cholesterol, LDL-C and HDL-C (<i>P</i> ≤ 0.04).</p><p><strong>Conclusions: </strong>Clinical and genetic factors contributed to the prediction of EWL and new-onset dyslipidaemia in three samples of patients who started at-risk psychotropic treatments. Future larger studies should be conducted to refine SNP estimates to be integrated into clinically applicable predictive models.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"10 6","pages":"e227"},"PeriodicalIF":3.9,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11698187/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142779326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The anomalous effect of COVID-19 pandemic restrictions on the duration of untreated psychosis.","authors":"Jessica Nicholls-Mindlin, Hadar Hazan, Bin Zhou, Fangyong Li, Maria Ferrara, Nina Levine, Sarah Riley, Sneha Karmani, Walter S Mathis, Matcheri S Keshavan, Vinod H Srihari","doi":"10.1192/bjo.2024.813","DOIUrl":"10.1192/bjo.2024.813","url":null,"abstract":"<p><p>We investigated the impact of COVID-19 restrictions on the duration of untreated psychosis (DUP). First-episode psychosis admissions (<i>n</i> = 101) to the STEP Clinic in Connecticut showed DUP reduction (<i>P</i> = 0.0015) during the pandemic, with the median reducing from 208 days pre-pandemic to 56 days in the early pandemic period, and subsequently increasing to 154 days (<i>P</i> = 0.0281). Time from psychosis onset to antipsychotic prescription decreased significantly in the pandemic (<i>P</i> = 0.0183), with the median falling from 117 to 35 days. This cohort study demonstrates an association between greater pandemic restrictions and marked DUP reduction, and provides insights for future early detection efforts.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"10 6","pages":"e216"},"PeriodicalIF":3.9,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11698182/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142766061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gender inequalities in the disruption of long-term life satisfaction trajectories during the COVID-19 pandemic and the role of time use: evidence from a prospective cohort study.","authors":"Darío Moreno-Agostino, Jenny Chanfreau, Gemma Knowles, Alina Pelikh, Jayati Das-Munshi, George B Ploubidis","doi":"10.1192/bjo.2024.817","DOIUrl":"10.1192/bjo.2024.817","url":null,"abstract":"<p><strong>Background: </strong>The COVID-19 pandemic has disproportionately affected women's mental health. However, most evidence has focused on mental illbeing outcomes, and there is little evidence on the mechanisms underlying this unequal impact.</p><p><strong>Aims: </strong>To investigate gender differences in the long-term trajectories of life satisfaction, how these were affected during the pandemic and the role of time-use differences in explaining gender inequalities.</p><p><strong>Method: </strong>We used data from 6766 (56.2% women) members of the 1970 British Cohort Study (BCS70). Life satisfaction was prospectively assessed between the ages of 26 (1996) and 51 (2021) years, using a single question with responses ranging from 0 (lowest) to 10 (highest). We analysed life satisfaction trajectories with piecewise latent growth curve models, and investigated whether gender differences in the change in the life satisfaction trajectories with the pandemic were explained by self-reported time spent doing different paid and unpaid activities.</p><p><strong>Results: </strong>Women had consistently higher life satisfaction than men before the pandemic (Δ_{intercept,unadjusted} = 0.213, 95% CI 0.087-0.340; <i>P =</i> 0.001) and experienced a more accelerated decline with the pandemic onset (Δ_{quad2,unadjusted} = -0.018, 95% CI -0.026 to -0.011; <i>P</i> < 0.001). Time-use differences did not account for the more accelerated decrease in women's life satisfaction levels with the pandemic (Δ_{quad2,adjusted} = -0.016, 95% CI -0.031 to -0.001; <i>P</i> = 0.035).</p><p><strong>Conclusions: </strong>Our study shows pronounced gender inequalities in the impact of the pandemic on the long-term life satisfaction trajectories of adults in their 50s, with women losing their pre-pandemic advantage over men. Self-reported time-use differences did not account for these inequalities. More research is needed to tackle gender inequalities in population mental health.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"10 6","pages":"e217"},"PeriodicalIF":3.9,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11698164/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142766005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antipsychotic medications and risk of respiratory failure in the respiratory high dependency unit.","authors":"Sara Winter, Tara Kirkpatrick, Karl Winckel, Faraz Honarparvar, Lewis Robinson, Timothy Tanzer, Lesley Smith, Nicola Warren, Dan Siskind, Claire Michelle Ellender","doi":"10.1192/bjo.2024.773","DOIUrl":"10.1192/bjo.2024.773","url":null,"abstract":"<p><strong>Background: </strong>There is a high incidence of serious mental illness (SMI) and antipsychotic use in the respiratory high dependence unit (HDU) compared with the general population. However, there is a paucity of data in the extant literature evaluating the relationships between respiratory failure and antipsychotics.</p><p><strong>Aims: </strong>To investigate the relationship between antipsychotics and respiratory failure in people admitted to a respiratory HDU, and to gain a better understanding of the potential impact of antipsychotic medications on respiratory outcomes.</p><p><strong>Method: </strong>Medical, demographic and clinical outcome data were collected for a consecutive sample of 638 individuals admitted to a respiratory HDU between the dates 1 January 2018 and 29 May 2021 at a large quaternary hospital.</p><p><strong>Results: </strong>Multivariate models controlling for confounders found that antipsychotic medications increased risk of admission for type 2 respiratory failure and chronic obstructive pulmonary disease exacerbation without hypercapnia by 3.7 and 11.45 times, respectively. For people admitted with type 2 respiratory failure, antipsychotic use increased the risk of requiring non-invasive ventilation by 4.9 times. Those prescribed an antipsychotic were more likely to be readmitted within 30 days. Over 30% of individuals were prescribed antipsychotics for an unlicensed indication.</p><p><strong>Conclusions: </strong>Poor respiratory outcomes may be a previously unknown adverse drug reaction of antipsychotics. Modifications to clinical care and clinical pathways for those with SMI prescribed antipsychotic medications, including optimising their chronic health and deprescribing where appropriate, should be prioritised.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"10 6","pages":"e211"},"PeriodicalIF":3.9,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11698217/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142766077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Childhood risk factors and clinical and service outcomes in adulthood in people with intellectual disabilities.","authors":"B Perera, S Mufti, C Norris, A Baksh, V Totsika, A Hassiotis, P Hurks, T van Amelsvoort","doi":"10.1192/bjo.2024.811","DOIUrl":"10.1192/bjo.2024.811","url":null,"abstract":"<p><strong>Background: </strong>Adults with intellectual disability experience increased rates of mental health disorders and adverse mental health outcomes.</p><p><strong>Aim: </strong>Explore childhood risk factors associated with adverse mental health outcomes during adulthood as defined by high cost of care, use of psychotropic medication without a severe mental illness and psychiatric hospital admissions.</p><p><strong>Method: </strong>Data on 137 adults with intellectual disability were collected through an intellectual disability community service in an inner London borough. Childhood modifiable and non-modifiable risk factors were extracted from records to map onto variables identified as potential risk factors. Logistic and linear regression models were employed to analyse their associations with adverse outcomes.</p><p><strong>Results: </strong>We showed that the co-occurrence of intellectual disability with autism spectrum disorder and/or attention-deficit hyperactivity disorder (ADHD) were associated with psychotropic medication use and high-cost care packages. However, when challenging behaviour during childhood was added, ADHD and autism spectrum disorder were no longer significant and challenging behaviour better explained medication prescribing and higher cost care. In addition, the severity of intellectual disability was associated with higher cost care packages. Ethnicity (Black and mixed) also predicted higher cost of care.</p><p><strong>Conclusions: </strong>Challenging behaviour during childhood emerged as a critical variable affecting outcomes in young adulthood and mediated the association between adult adverse mental health outcomes and co-occurring neurodevelopmental conditions, that is, ADHD and autism. These findings emphasise the need for effective early intervention strategies to address challenging behaviour during childhood. Such interventions for challenging behaviour will need to take into consideration autism and ADHD.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"10 6","pages":"e218"},"PeriodicalIF":3.9,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11698209/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142766004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-harm-related mental health presentations to emergency departments by children and young people from culturally and linguistically diverse groups in South Western Sydney.","authors":"James Rufus John, Jahidur Rahman Khan, Paul M Middleton, Yao Huang, Daniel Ping-I Lin, Nan Hu, Bin Jalaludin, Paul Chay, Raghu Lingam, Valsamma Eapen","doi":"10.1192/bjo.2024.763","DOIUrl":"10.1192/bjo.2024.763","url":null,"abstract":"<p><strong>Background: </strong>Rates of self-harm among children and young people (CYP) have been on the rise, presenting major public health concerns in Australia and worldwide. However, there is a scarcity of evidence relating to self-harm among CYP from culturally and linguistically diverse (CALD) backgrounds.</p><p><strong>Aims: </strong>To analyse the relationship between self-harm-related mental health presentations of CYP to emergency departments and CALD status in South Western Sydney (SWS), Australia.</p><p><strong>Method: </strong>We analysed electronic medical records of mental health-related emergency department presentations by CYP aged between 10 and up to 18 years in six public hospitals in the SWS region from January 2016 to March 2022. A multilevel logistic regression model was used on these data to assess the association between self-harm-related presentations and CALD status while adjusting for covariates and individual-level clustering.</p><p><strong>Results: </strong>Self-harm accounted for 2457 (31.5%) of the 7789 mental health-related emergency department presentations by CYP; CYP from a CALD background accounted for only 8% (<i>n</i> = 198) of the self-harm-related presentations. CYP from the lowest two most socioeconomic disadvantaged areas made 63% (<i>n</i> = 1544) of the total self-harm-related presentations. Findings of the regression models showed that CYP from a CALD background (compared with those from non-CALD backgrounds) had 19% lower odds of self-harm (adjusted odds ratio 0.81, 95% CI 0.66-0.99).</p><p><strong>Conclusions: </strong>Findings of this study provide insights into the self-harm-related mental health presentations and other critical clinical features related to CYP from CALD backgrounds that could better inform health service planning and policy to manage self-harm presentations and mental health problems among CYP.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"10 6","pages":"e213"},"PeriodicalIF":3.9,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11698175/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142766043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The hypothalamic-pituitary-thyroid axis, depression and risk of suicide: commentary, Luo et al.","authors":"Charles B Nemeroff","doi":"10.1192/bjo.2024.750","DOIUrl":"10.1192/bjo.2024.750","url":null,"abstract":"<p><p>There is a considerable literature on the relationship of thyroid function with risk of depression and responsiveness to depression treatment. This literature is briefly reviewed here, followed by a focus on the incremental advance provided by the findings of Luo et al on autoimmune thyroiditis and suicide attempts.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"10 6","pages":"e212"},"PeriodicalIF":3.9,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11698143/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142766064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep disturbances and racial-ethnic disparities in 10-year dementia risk among a national sample of older adults in the USA.","authors":"Roger Wong, Jason Rafael Grullon","doi":"10.1192/bjo.2024.814","DOIUrl":"10.1192/bjo.2024.814","url":null,"abstract":"<p><strong>Background: </strong>Race/ethnicity and sleep disturbances are associated with dementia risk.</p><p><strong>Aims: </strong>To explore racial-ethnic disparities in sleep disturbances, and whether race/ethnicity moderates the relationship between sleep disturbances and dementia risk among older adults.</p><p><strong>Method: </strong>We analysed ten annual waves (2011-2020) of prospective cohort data from the National Health and Aging Trends Study, a nationally representative USA sample of 6284 non-Hispanic White (<i>n</i> = 4394), non-Hispanic Black (<i>n</i> = 1311), Hispanic (<i>n</i> = 342) and non-Hispanic Asian (<i>n</i> = 108) community-dwelling older adults. Sleep disturbances were converted into three longitudinal measures: (a) sleep-initiation difficulty (trouble falling asleep within 30 min), (b) sleep-maintenance difficulty (trouble falling asleep after waking up early) and (c) sleep medication usage (taking medication to sleep). Cox proportional hazards models analysed time to dementia, after applying sampling weights and adjusting for sociodemographic characteristics and health.</p><p><strong>Results: </strong>Black, Hispanic and Asian respondents exhibited higher frequencies of sleep-initiation and sleep-maintenance difficulties, but had less sleep medication usage, compared with White older adults. Among Hispanic respondents, sleep-initiation difficulty was associated with significantly decreased dementia risk (adjusted hazard ratio (aHR) = 0.34, 95% CI 0.15-0.76), but sleep-maintenance difficulty was associated with increased dementia risk (aHR = 2.68, 95% CI 1.17-6.13), compared with White respondents. Asian respondents using sleep medications had a significantly higher dementia risk (aHR = 3.85, 95% CI 1.64-9.04). There were no significant interactions for Black respondents.</p><p><strong>Conclusions: </strong>Sleep disturbances are more frequent among older Black, Hispanic and Asian adults, and should be considered when addressing dementia disparities. Research is needed to explore how certain sleep disturbances may elevate dementia risk across different racial and ethnic subgroups.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"10 6","pages":"e219"},"PeriodicalIF":3.9,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11698159/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142766046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors associated with mental health outcomes in a Muslim community following the Christchurch terrorist attack.","authors":"Caroline Bell, Ruqayya Sulaiman-Hill, Sandila Tanveer, Richard Porter, Shaystah Dean, Philip J Schluter, Ben Beaglehole, Joseph M Boden","doi":"10.1192/bjo.2024.774","DOIUrl":"10.1192/bjo.2024.774","url":null,"abstract":"<p><strong>Background: </strong>On 15 March 2019, a white supremacist terrorist attacked two mosques in Christchurch, New Zealand. Fifty-one people were killed and another 40 sustained non-fatal gunshot injuries.</p><p><strong>Aims: </strong>To examine the mental health of the Muslim community, and individual and exposure-related factors associated with mental health outcomes.</p><p><strong>Method: </strong>This is the baseline analysis of a longitudinal study of adults from the Muslim community interviewed 11-32 months after the shootings. It included a diagnostic interview (MINI), measures of sociodemographic factors, prior mental health, prior traumatic events, exposure in the attacks, discrimination, life stressors, social support and religious coping. Logistic regression models examined associations with mental health outcomes.</p><p><strong>Results: </strong>The sample comprised 189 participants (mean age 41 (s.d. = 13); 60% female), and included: bereaved, 17% (<i>n</i> = 32); injured survivors 12% (<i>n</i> = 22); non-injured survivors, 19% (<i>n</i> = 36); family members of survivors, 35% (<i>n</i> = 67); and community members without the above exposures, 39% (<i>n</i> = 74). Overall, 61% had at least one mental disorder since the attacks. Those bereaved (<i>P</i> < 0.01, odds ratio 4.28, 95% CI 1.75-10.49) and survivors, whether injured (<i>P</i> < 0.001, odds ratio 18.08, 95% CI 4.70-69.60) or not (<i>P</i> < 0.01, odds ratio 5.26, 95% CI 1.99-13.89), had greater odds of post-traumatic stress disorder. Those bereaved (<i>P</i> < 0.001, odds ratio 5.79, 95% CI 2.49-13.46) or injured (<i>P</i> = 0.04, odds ratio 4.43, 95% CI 1.07-18.28) had greater odds of depression.</p><p><strong>Conclusions: </strong>Despite unique features of this attack on a Muslim population, findings accord with previous studies. They suggest generalisability of psychopathology after terror attacks, and that being bereaved or directly experiencing such events is associated with adverse mental health outcomes.</p><p><strong>Trial registration number: </strong>The study is registered on the Australian NZ Clinical Trials Registry (ACTRN12620000909921).</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"10 6","pages":"e209"},"PeriodicalIF":3.9,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11698172/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142614129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}