BJPsych Open最新文献

{"title":"'She's so knowledgeable about autism': autistic women and birthing people's experiences of specialist perinatal mental health teams.","authors":"Verity Westgate, Caitlin Thompson, Doretta Caramaschi, Heather A O'Mahen","doi":"10.1192/bjo.2026.12045","DOIUrl":"10.1192/bjo.2026.12045","url":null,"abstract":"<p><strong>Background: </strong>Autistic women and birthing people (AWBP) are at heightened risk of perinatal mental health difficulties such as perinatal anxiety and depression, yet little is known about their experiences of support from specialist perinatal mental health teams (SPMHTs).</p><p><strong>Aims: </strong>We aimed to understand the experiences of AWBP engaging with support from SPMHTs.</p><p><strong>Methods: </strong>We conducted semi-structured interviews with 18 participants from 4 SPMHTs in England to explore their experiences and perceptions of care. We used codebook thematic analysis to identify and develop themes that captured and explained patterns within the data.</p><p><strong>Results: </strong>We identified three themes: (a) seeing the whole person: for many, SPMHT involvement was the first time autism was recognised or explored in a mental health context. Participants valued opportunities for formal assessment, which supported self-understanding and highlighted the need for integrated care addressing both autistic and mental health needs. (b) Experiencing SPMHT care as an autistic person: participants valued care that accommodated their needs and preferences, particularly practical interventions, although several reported unmet needs and many found discharge challenging. (c) Ideas for service improvement: participants recommended access to autism-informed practitioners and peer groups tailored for AWBP.</p><p><strong>Conclusions: </strong>This study highlights how SPMHT care that recognises and responds to the distinct needs of AWBP can make a meaningful difference. AWBP valued holistic, autism-informed perinatal mental healthcare that recognised their communication, sensory and cognitive needs. Accessing assessment for a formal diagnosis supported the development of identity as an autistic person, helping to make sense of challenges in the perinatal period.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"12 4","pages":"e187"},"PeriodicalIF":4.0,"publicationDate":"2026-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13372804/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148435162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychiatric symptoms of long COVID among adults: observational case-control study in Johannesburg, South Africa.","authors":"Andrew Wooyoung Kim, Someleze Swana, Simiso Sokhela, Samanta Lalla-Edward, Ncomeka Manentsa, Alexander C Tsai, W D Francois Venter","doi":"10.1192/bjo.2026.12049","DOIUrl":"10.1192/bjo.2026.12049","url":null,"abstract":"<p><strong>Background: </strong>Growing research has underscored the elevated prevalence and burden of psychiatric morbidity among adults living with long COVID. The severity of acute SARS-CoV-2 infection may predict the prevalence and severity of psychiatric symptoms in long COVID. Although Global South countries have faced among the highest incidence rates and burden of COVID-19, little is known about the psychiatric symptoms of long COVID in these regions, especially in Sub-Saharan Africa.</p><p><strong>Aims: </strong>This study aimed to (a) compare the prevalence of long-term psychiatric symptoms between acute COVID-19 infection groups, (b) estimate the associations between COVID-19 severity and long-term psychiatric symptoms, (c) determine the association between long COVID symptoms and psychiatric symptoms, and (d) test the potential mediating effect of long COVID symptoms in the association between acute COVID-19 infection and psychiatric symptoms.</p><p><strong>Method: </strong>This case-control study took place in Johannesburg, South Africa, between August 2022 and July 2023. A total of 360 adults were categorised into one of four case groups based on initial COVID-19 symptoms: asymptomatic, symptomatic, admitted to hospital and vaccinated controls.</p><p><strong>Results: </strong>Prevalence rates of post-traumatic stress disorder (21.1%) and somatic symptoms (22.9%) were elevated. Individuals with symptomatic COVID-19 exhibited the greatest psychiatric morbidity out of all groups, exhibiting the highest levels of depression, suicidality, anxiety, post-traumatic stress disorder, bipolar disorder and somatisation. Acute COVID-19 severity was associated with worse symptoms of depression, somatisation and physical fatigue. Severity of long COVID symptoms was directly associated with psychiatric sequelae.</p><p><strong>Conclusions: </strong>These results call attention to the long-term psychiatric sequelae of SARS-CoV-2 infection and early identification and management of emerging psychiatric symptoms in high-risk COVID-19 survivors.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"12 4","pages":"e184"},"PeriodicalIF":4.0,"publicationDate":"2026-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13372805/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148435174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors linked to successful brain magnetic resonance imaging scans and data quality in autistic individuals across the functioning spectrum.","authors":"Lin-Wan Huang, Yi Ran Zhou, Chun-Hung Yeh, Hsing-Chang Ni, Benoit H Mulsant, Muhammad Ishrat Husain, Jung-Chi Chang, En-Nien Tu, Mei-Yun Hsu, Yu-Yu Wu, Tai-Li Chou, Susan Shur-Fen Gau, Hsiang-Yuan Lin","doi":"10.1192/bjo.2026.12035","DOIUrl":"10.1192/bjo.2026.12035","url":null,"abstract":"<p><strong>Background: </strong>Neuroimaging research in autism often excludes individuals with co-occurring intellectual impairment or minimally verbal status, limiting the generalisability of findings. Understanding magnetic resonance imaging (MRI) scan success predictors in a representative autistic sample is crucial for equitable research.</p><p><strong>Aims: </strong>This study identified factors predicting successful brain MRI acquisition and data quality in diverse autistic individuals, focusing on including those with intellectual impairment or minimally verbal status.</p><p><strong>Method: </strong>A total of 122 participants (83 autistic individuals (27 with intellectual impairment, 19 with minimally verbal status) and 39 typically developing controls) received multi-modal brain MRI scans (including structural, resting-state functional and diffusion MRI). Scan success, assessed using both binary criteria and quantitative data-quality metrics, was related to participant characteristics.</p><p><strong>Results: </strong>Although overall scan success was high, specific factors differentiated success within subgroups. Key factors contributing to scan success included age, non-verbal intelligence and attention-deficit hyperactivity disorder (ADHD) symptoms. Older participants, those with fewer ADHD symptoms and those with higher non-verbal intelligence were more likely to achieve successful scans, regardless of autism diagnosis. Higher data quality, particularly in structural and functional MRI, was associated with higher intelligence, better adaptive functioning, fewer autistic and ADHD symptoms, and fewer behavioural problems.</p><p><strong>Conclusions: </strong>Identifying these factors is key to designing more inclusive and effective neuroimaging protocols. This work paves the way for more comprehensive research into the neurobiology of the full autism spectrum, and offers insights for improving the clinical MRI experience for autistic individuals with diverse support needs. Individualised strategies may also be useful in clinical settings, helping to improve the experience of MRI scanning for autistic individuals.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"12 4","pages":"e186"},"PeriodicalIF":4.0,"publicationDate":"2026-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13372812/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148435117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"'Mental health was always the last; always an afterthought': policy analysis of domestic financing and prioritisation for mental health in Ghana.","authors":"Leonard Baatiema, Leveana Gyimah, Joana Ansong, Dan Chisholm, Bruno Meessen","doi":"10.1192/bjo.2026.10984","DOIUrl":"10.1192/bjo.2026.10984","url":null,"abstract":"<p><strong>Background: </strong>Mental health remains a low health priority globally. Despite the high burden of mental health in Ghana, little is known about the extent of financing and prioritisation by policymakers and other relevant stakeholders.</p><p><strong>Aims: </strong>This study aims to understand the determinants of low domestic public financing and the prioritisation of mental health in Ghana, and to identify opportunities and strategies to increase policy attention.</p><p><strong>Method: </strong>Kingdon's multiple streams framework was used to map barriers to domestic financing for mental health. We conducted a document analysis of relevant policies, strategies and articles, and carried out semi-structured interviews with relevant national stakeholders. We analysed interview transcripts deductively following the key domains for the multiple streams framework.</p><p><strong>Results: </strong>We found that low public financing for mental health stems from several issues at the level of the 'problem stream': low awareness and misunderstandings in general society, stigma and discrimination, insufficient public funding of the health sector in general, catastrophic healthcare expenditure insufficiently documented, limited political attention to mental health and limited donor interest. There is clear evidence of dynamism on the 'policy solution stream', including development of national laws, policies, strategies and institutions; adoption of international strategies and recommendations; and existence of policy entrepreneurs and windows. The democratic system of Ghana creates opportunities in the 'politics stream', but also raises the issue of continuity across governments.</p><p><strong>Conclusions: </strong>In Ghana, mental health is not yet sufficiently recognised as a societal issue, which affects demand for services and contributes to the low policy priority and resource allocation by the government. Greater investment is therefore needed to raise public awareness through coalition building, research, campaigns and education activities.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"12 4","pages":"e185"},"PeriodicalIF":4.0,"publicationDate":"2026-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13372806/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148435101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patterns in health service use during and up to 1 year after an acute episode of hospital-presenting self-harm: data linkage cohort study of over 1.3 million records.","authors":"Katrina Witt, Daniel Z Q Gan, Caroline X Gao, Jonathan Knott, Annette Erlangsen, Trine Madsen, Lianne Schmaal","doi":"10.1192/bjo.2026.12033","DOIUrl":"10.1192/bjo.2026.12033","url":null,"abstract":"<p><strong>Background: </strong>Many people presenting to emergency departments after self-harm do not receive adequate care, even in well-resourced health systems.</p><p><strong>Aims: </strong>To identify patterns of health care service use across two periods: (a) during and (b) up to 1 year after an index emergency department self-harm presentation.</p><p><strong>Method: </strong>A retrospective population-based cohort study including 4668 individuals aged ≥9 years who presented to the Royal Melbourne Hospital emergency department for self-harm between January 2012 and December 2019. Linked administrative data captured >1.3 million records across primary care, pharmacy, specialist mental and physical health services and emergency departments. Sequential pattern mining identified longitudinal service-use clusters. Multinomial regression explored associations with demographic, clinical, psychosocial and presentation characteristics. Cox proportional hazards models assessed associations between clusters and all-cause and suicide mortality.</p><p><strong>Results: </strong>Emergency department self-harm presentations triggered short-term increases in multi-sector contacts. However, most (68.7%) reverted to the same service-use cluster observed prior to their index presentation. Suicide risk was highest within 1 year, particularly among those in the specialist mental health services cluster (4.5% of the cohort).</p><p><strong>Conclusions: </strong>A small subgroup engage intensively with specialist mental health services yet remain at high suicide risk, while one in ten remain disengaged altogether, suggesting that an acute presentation of self-harm often fails to alter patients' care trajectories long-term. Policy alignment with national recommendations for integrated, community-based care could improve sustained, evidence-based support beyond acute crises.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"12 4","pages":"e180"},"PeriodicalIF":4.0,"publicationDate":"2026-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13359047/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148418413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond discrimination: calibration and decision utility are required before GREAT can guide individual ECT decisions.","authors":"Juan Carlos Munguia, Yolly Molina, Patricia Soriano, Isaac Zablah","doi":"10.1192/bjo.2026.12048","DOIUrl":"10.1192/bjo.2026.12048","url":null,"abstract":"<p><p>Belz and colleagues present GREAT, a seven-item clinical instrument for predicting electroconvulsive therapy response in unipolar depression, with promising discriminatory validity (AUC 0.841). We identify three methodological gaps - absent calibration, limited sample representativeness and unquantified incremental value - that must be addressed before GREAT can guide individual clinical decisions.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"12 4","pages":"e183"},"PeriodicalIF":4.0,"publicationDate":"2026-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13359056/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148410034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy, safety and policy implications of anti-amyloid monoclonal antibodies for Alzheimer's disease: protocol for a living systematic review and meta-analysis.","authors":"Saehyeon Kim, Haruhiko Oda, Rie Oyama, Rei Makishi, Sohail Bade, Sahil Bade, Irshad Ally, Yuka Iijima, Yuki Gibo, Kota Minami, Fumitoshi Fukuzawa, Shohei Sanji, Kentaro Inamine, Hironori Kishi, Sunjun Huh, Takaki Tanifuji, Mone Nagahiro, Norio Watanabe","doi":"10.1192/bjo.2026.12044","DOIUrl":"10.1192/bjo.2026.12044","url":null,"abstract":"<p><strong>Background: </strong>Dementia affects approximately 6-13% of adults aged 65 years and older, with Alzheimer's disease accounting for most cases. Established symptomatic therapies, including acetylcholinesterase inhibitors and memantine, provide limited benefit and do not modify disease progression. Multiple monoclonal antibodies (mABs) targeting different amyloid-β species have been developed as potential disease-modifying therapies; because some agents have entered clinical use whereas others remain investigational, a continuously updated synthesis of their efficacy and safety is needed.</p><p><strong>Aims: </strong>To evaluate the efficacy and safety of all anti-amyloid mABs for adults with Alzheimer's disease, using a living systematic review and meta-analysis.</p><p><strong>Method: </strong>We will conduct a living systematic review and meta-analysis in accordance with the Cochrane Handbook, Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) 2020 and the PRISMA extension for living systematic reviews. Randomised controlled trials comparing any approved or investigational anti-amyloid mAB with placebo, standard care or active comparators will be included. Searches of Ovid MEDLINE, Embase, Cochrane Central Register of Controlled Trials, ClinicalTrials.gov and WHO International Clinical Trials Registry Platform will be updated every 6 months. Meta-analyses will be conducted separately for each antibody molecule using random-effects models. Critical outcomes include global clinical change and disease severity, cognitive abilities, functional ability and dependency, and safety (serious adverse events, treatment discontinuation and amyloid-related imaging abnormalities). Important outcomes include neuropsychiatric symptoms, quality of life and health system outcomes. Certainty of evidence will be assessed using the methodology Grading of Recommendations, Assessment, Development and Evaluation.</p><p><strong>Results: </strong>This article describes a protocol; therefore, no review findings are available at this stage.</p><p><strong>Conclusions: </strong>This living systematic review will provide an up-to-date synthesis of the benefits and harms of anti-amyloid monoclonal antibodies to inform clinical decision-making and health-system planning in Alzheimer's disease.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"12 4","pages":"e182"},"PeriodicalIF":4.0,"publicationDate":"2026-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13359045/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148410061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Human rights-based mental healthcare: new developments, introducing a themed series of papers.","authors":"Helen Herrman, Paul S Appelbaum, Silvana Galderisi, Norman Sartorius, John Allan, Martha Savage, Maria Rodrigues, Neeraj Gill, Guadalupe Morales Cano","doi":"10.1192/bjo.2026.12022","DOIUrl":"10.1192/bjo.2026.12022","url":null,"abstract":"<p><p>Mental healthcare respecting human rights is a worldwide need, yet research into practices that support such rights is limited. The United Nations Convention on the Rights of Persons with Disabilities, 2006 and the United Nations Resolution on mental health and psychosocial support, 2023 each heighten the urgency and the legal, as well as moral, social, political and other obligations to improve the quality of mental healthcare and respect human rights worldwide. It is useful to be specific about the actions to be taken, as done in recent programmes by the World Psychiatric Association and the World Health Organization. The work requires partnerships at all levels, from global to local, among healthcare professionals, people with lived experience and their families, communities and policy-makers. We present a themed series of papers developed in two parts: one related to principles of human rights-based mental healthcare; the other to assessment, policy and actions needed for tackling the implementation gap.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"12 4","pages":"e179"},"PeriodicalIF":4.0,"publicationDate":"2026-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13359051/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148403498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reintegration programmes for people with severe mental illnesses released from correctional institutions: systematic review.","authors":"Alexander I F Simpson, M Umer Waqar, Cory Gerritsen, Vito Adamo, Marco Kilada, Margaret Maheandiran, Reena Besa, Roland M Jones","doi":"10.1192/bjo.2026.12034","DOIUrl":"10.1192/bjo.2026.12034","url":null,"abstract":"<p><strong>Background: </strong>People with severe mental illness (SMI) face significant challenges when reintegrating from correctional facilities back to the community. These include increased recidivism risk, homelessness and mental health deterioration. Although specialised reintegration programmes were developed to address the needs of this vulnerable population, their effectiveness remains unclear owing to mixed findings reported in the literature.</p><p><strong>Aims: </strong>We performed a systematic review to synthesise and evaluate available evidence on reintegration programmes designed specifically for people with SMI.</p><p><strong>Method: </strong>Studies were included if they focused on adults with SMI transitioning from correctional facilities to community settings. The search was conducted through 10 January 2026. Two reviewers independently screened eligible studies and scored the appropriate risk of bias tools under supervision. A narrative analysis was adopted given the heterogeneity of methodologies and outcomes.</p><p><strong>Results: </strong>We identified 26 eligible studies, of which 11 were longitudinal, seven were randomised controlled trials, 3 had an AB design, 2 quasi-experimental, 2 retrospective and 1 brief report. The median number of participants involved in these studies was 207 (range: 22-3086). Studies employed various interventions, including peer mentoring, critical time intervention models, case management and therapeutic community. Results showed mixed effectiveness: some programmes demonstrated reduced recidivism and improved mental health service engagement, whereas others had minimal impact or even counterintuitive increases in re-imprisonment. Programmes generally showed better outcomes with a longer duration and comprehensive aftercare components.</p><p><strong>Conclusions: </strong>Reintegration programmes show promise, but current approaches demonstrate variable efficacy. Successful interventions appear to require comprehensive, sustained support addressing multiple domains including mental health treatment, housing, employment and social support.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"12 4","pages":"e181"},"PeriodicalIF":4.0,"publicationDate":"2026-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13359055/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148403556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of cannabis potency on mental health outcomes among adolescents and young adults: scoping review.","authors":"Chloe Hambly Lapointe, Lilith Nosko, Candice E Crocker, Philip G Tibbo","doi":"10.1192/bjo.2026.12023","DOIUrl":"10.1192/bjo.2026.12023","url":null,"abstract":"<p><strong>Background: </strong>Recently, there has been a significant rise in potency (% tetrahydrocannabinol (THC)) of cannabis products globally. As such, there is a need for a better understanding of the relationship between cannabis potency and mental health outcomes, especially in a developmentally vulnerable population such as adolescents and young adults.</p><p><strong>Aims: </strong>The objective of this scoping review was to summarise existing literature investigating the potency of cannabis products as it relates to mental health outcomes in adolescents and young adults aged 14-25.</p><p><strong>Method: </strong>Systematic searches of MEDLINE, Embase, CINAHL and PsycINFO were conducted for relevant manuscripts up to October 2025. Following PRISMA-ScR guidelines, retrieved studies were then screened and data extracted by two independent reviewers.</p><p><strong>Results: </strong>Out of 11 225 studies identified by our searches, 71 were included in the review after screening. Compared with low-potency cannabis, our findings suggest that high-potency cannabis is more strongly associated with severe mental health issues, such as cannabis dependence, psychosis and cognitive deficits.</p><p><strong>Conclusions: </strong>Overall, it was found that high-potency cannabis use (>15% THC) was associated with a great number and magnitude of adverse mental health outcomes. As such, the potency of cannabis products should be measured in future cannabis research that investigates short- and long-term outcomes. Additionally, the potency of cannabis products should be a consideration in any future cannabis regulatory policy discussions.</p>","PeriodicalId":9038,"journal":{"name":"BJPsych Open","volume":"12 4","pages":"e177"},"PeriodicalIF":4.0,"publicationDate":"2026-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13359059/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148395691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}