BMC Pregnancy and Childbirth最新文献

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Rheumatoid arthritis and adverse pregnancy outcomes: a bidirectional two-sample mendelian randomization study. 类风湿性关节炎与不良妊娠结局:一项双向双样本门德尔随机研究。
IF 2.8 2区 医学
BMC Pregnancy and Childbirth Pub Date : 2024-07-31 DOI: 10.1186/s12884-024-06698-3
Tongmin Chang, Zengle Zhao, Xiaoyan Liu, Xuening Zhang, Yuan Zhang, Xinjie Liu, Yuan Zhang, Ming Lu
{"title":"Rheumatoid arthritis and adverse pregnancy outcomes: a bidirectional two-sample mendelian randomization study.","authors":"Tongmin Chang, Zengle Zhao, Xiaoyan Liu, Xuening Zhang, Yuan Zhang, Xinjie Liu, Yuan Zhang, Ming Lu","doi":"10.1186/s12884-024-06698-3","DOIUrl":"10.1186/s12884-024-06698-3","url":null,"abstract":"<p><strong>Background: </strong>There is growing evidence of bidirectional associations between rheumatoid arthritis and adverse pregnancy outcomes (APOs) in observational studies, but little is known about the causal direction of these associations. Therefore, we explored the potential causal relationships between rheumatoid arthritis and APOs using a bidirectional two-sample Mendelian randomization (MR) in European and Asian populations.</p><p><strong>Methods: </strong>We conducted a bidirectional two-sample Mendelian randomization analysis using available summary statistics from released genome-wide association studies. Summary statistics for instrument-outcome associations were retrieved from two separate databases for rheumatoid arthritis and adverse pregnancy outcomes, respectively. The inverse-variance weighted method was used as the primary MR analysis, and cML-MA-BIC was used as the supplementary analysis. MR-Egger, MR pleiotropy residual sum and outlier (MR-PRESSO), and Cochran Q statistic method were implemented as sensitivity analyses approach to ensure the robustness of the results.</p><p><strong>Results: </strong>Our study showed that a higher risk of rheumatoid arthritis in the European population was associated with gestational hypertension (OR: 1.04, 95%CI: 1.02-1.06), pre-eclampsia (OR: 1.06, 95%CI: 1.01-1.11), fetal growth restriction (OR: 1.08, 95%CI: 1.04-1.12), preterm delivery (OR:1.04, 95%CI: 1.01-1.07). Furthermore, we found no evidence that APOs had causal effects on rheumatoid arthritis in the reverse MR analysis. No association between rheumatoid arthritis and APOs was found in East Asian population. There was no heterogeneity or horizontal pleiotropy.</p><p><strong>Conclusions: </strong>This MR analysis provides the positive causal association from rheumatoid arthritis to gestational hypertension, pre-eclampsia, fetal growth restriction and preterm delivery genetically. It highlights the importance of more intensive prenatal care and early intervention among pregnant women with rheumatoid arthritis to prevent potential adverse obstetric outcomes.</p>","PeriodicalId":9033,"journal":{"name":"BMC Pregnancy and Childbirth","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11293129/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141858996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trends and causes of maternal mortality in Indonesia: a systematic review. 印度尼西亚孕产妇死亡率的趋势和原因:系统回顾。
IF 2.8 2区 医学
BMC Pregnancy and Childbirth Pub Date : 2024-07-30 DOI: 10.1186/s12884-024-06687-6
M Syairaji, Detty Siti Nurdiati, Bayu Satria Wiratama, Zita D Prüst, Kitty W M Bloemenkamp, Kim J C Verschueren
{"title":"Trends and causes of maternal mortality in Indonesia: a systematic review.","authors":"M Syairaji, Detty Siti Nurdiati, Bayu Satria Wiratama, Zita D Prüst, Kitty W M Bloemenkamp, Kim J C Verschueren","doi":"10.1186/s12884-024-06687-6","DOIUrl":"10.1186/s12884-024-06687-6","url":null,"abstract":"<p><strong>Background: </strong>The maternal mortality ratio (MMR) in Indonesia is among the highest in Southeast Asia. We aim to describe trends in the MMR and causes of maternal deaths in Indonesia over the past decades, regionally and nationally.</p><p><strong>Methods: </strong>We performed a systematic review and conducted a search using PubMed, Embase, Global Health, CINAHL, Cochrane, Portal Garuda, and Google Scholar from the inception of the database to April 2023. We included all studies on the incidence and/or the causes of maternal deaths in Indonesia. The MMR was defined as the number of maternal deaths per 100,000 live births. Maternal death causes were assessed and reclassified according to the WHO International Classification of Disease Maternal Mortality (ICD-MM).</p><p><strong>Results: </strong>We included 63 studies that reported the MMR (54 studies) and/or the causes of maternal deaths (44 studies) in Indonesia from 1970 to 2022, with a total of 254,796 maternal deaths. The national MMR declined from 450 to 249 (45%) between 1990 and 2020. Great differences in MMR exist across the country, with the lowest in Java-Bali and the highest (more than twice the national MMR) in Sulawesi and Eastern Indonesia. Between 1990 and 2022, the proportion of deaths due to hemorrhage and sepsis decreased, respectively from 48 to 18% and 15-5%, while the share of deaths due to hypertensive disorders and non-obstetric causes increased, respectively from 8 to 19% and 10-49%.</p><p><strong>Conclusion: </strong>Despite the steady decline of maternal deaths in Indonesia, it remains one of the highest in Southeast Asia, with enormous disparities within the country. Hypertensive disorders and non-communicable diseases make up a growing share of maternal deaths, making maternal death reduction strategies increasingly challenging. National Maternal Death Surveillance and Response needs to be prioritized to eliminate preventable maternal deaths in Indonesia.</p><p><strong>Registration of systematic reviews: </strong>PROSPERO, CRD42022320213.</p>","PeriodicalId":9033,"journal":{"name":"BMC Pregnancy and Childbirth","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11290122/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141854736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perinatal maternal factors influencing postpartum feeding practices at six weeks. 影响产后六周喂养方式的围产期孕产妇因素。
IF 2.8 2区 医学
BMC Pregnancy and Childbirth Pub Date : 2024-07-30 DOI: 10.1186/s12884-024-06711-9
Yanchi Wang, Kai Mao, Minjie Chu, Xiaopeng Lu
{"title":"Perinatal maternal factors influencing postpartum feeding practices at six weeks.","authors":"Yanchi Wang, Kai Mao, Minjie Chu, Xiaopeng Lu","doi":"10.1186/s12884-024-06711-9","DOIUrl":"10.1186/s12884-024-06711-9","url":null,"abstract":"<p><strong>Objective: </strong>Despite the World Health Organization's recommendation of exclusive breastfeeding for the initial 6 months, breastfeeding rates decline within the first 6 weeks after delivery. This study aimed to (1) investigate the breastfeeding rate at 6 weeks postpartum and (2) explore the influence of perinatal factors on feeding patterns at 6 weeks postpartum.</p><p><strong>Method: </strong>A total of 635 participants were enrolled from February to August 2023 at outpatient clinics in three tertiary hospitals in Nantong City. Variables were collected through questionnaires during the third trimester of pregnancy, including demographic information, pregnancy stress, anxiety, depression, sleep, and resilience. At 6 weeks postpartum, information regarding feeding patterns, delivery and postpartum situations, postpartum stress, anxiety, depression, sleep, and resilience was gathered. Initial single-factor analyses were conducted using feeding pattern as the dependent variable, and variables with significance were chosen as independent variables. The disordered multi-classification logistic regression model was then established using the stepwise forward method.</p><p><strong>Results: </strong>Within the first 6 weeks, 35.28% (224/635) of postpartum women exclusively breastfed their infants. Factors influencing exclusive breastfeeding and formula feeding at 6 weeks postpartum included breast pain, sleep quality, mental resilience, difference between postpartum and late pregnancy anxiety, insufficient milk supply, and maternal herself caring for the infant (P < 0.05). Factors influencing the transition from exclusive to partial breastfeeding were insufficient milk supply and maternal herself caring for the infant (P < 0.05).</p><p><strong>Conclusion: </strong>The study reveals a relative low rate of exclusive breastfeeding in China's first 6 weeks postpartum, along with a comparison of perinatal factors affecting three different feeding patterns. Our findings may contribute additional evidence to the association between perinatal factors and feeding patterns. This study guides healthcare professionals in developing strategies to promote exclusive breastfeeding and improve personalized counseling for exclusive breastfeeding and mental health.</p>","PeriodicalId":9033,"journal":{"name":"BMC Pregnancy and Childbirth","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11290058/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141854734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The implementation of online and offline hybrid weight management approach for pregnant women based on the Fogg behavior model in Hainan, China: a pilot randomized controlled trial. 基于福格行为模式的线上线下混合体重管理方法在中国海南的实施:随机对照试验。
IF 2.8 2区 医学
BMC Pregnancy and Childbirth Pub Date : 2024-07-30 DOI: 10.1186/s12884-024-06699-2
Linjie Wang, Lanli Zou, Huanying Yi, Tong Li, Rong Zhou, Jing Yang, Jia Wang, Caihong Zhang, Honghua Guo
{"title":"The implementation of online and offline hybrid weight management approach for pregnant women based on the Fogg behavior model in Hainan, China: a pilot randomized controlled trial.","authors":"Linjie Wang, Lanli Zou, Huanying Yi, Tong Li, Rong Zhou, Jing Yang, Jia Wang, Caihong Zhang, Honghua Guo","doi":"10.1186/s12884-024-06699-2","DOIUrl":"10.1186/s12884-024-06699-2","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed at evaluating the effects of online and offline hybrid weight management approach based on the Fogg behavior model on total gestational weight gain and perinatal outcomes.</p><p><strong>Methods: </strong>Pregnant women in Hainan, the southernmost province of China, were recruited into a randomized controlled trial, which was designed to develop a WeChat platform for pregnancy weight management, and implement individualized and continuous pregnancy weight management services for pregnant women under the guidance of the Fogg behavior model. All pregnant women participating in the study were included in the full analysis set (FAS) for analysis. The pregnant women who completed the intervention and provided all outcome indicators were included in the per protocol set (PPS) for outcome evaluation.</p><p><strong>Results: </strong>Fifty-eight pregnant women were included in FAS analysis, and 52 pregnant women were finally included in PPS analysis. There was no statistically significant difference (P > 0.05) between the two groups at baseline. The gestational weight gain of the intervention group was significantly lower than that of the control group (P < 0.05). In the control group, the rate of appropriate weight gain during pregnancy was 48.26%, the rate of appropriate weight gain during pregnancy was 93.30% in the intervention group, with a statistically significant difference (P < 0.05). In the delivery outcomes, the cesarean section rate in the intervention group was significantly lower than that in the control group, and the differences were statistically significant (P < 0.05). The incidence of gestational diabetes mellitus and gestational hypertension in the intervention group was lower than those in the control group, and the differences were statistically significant (P < 0.05). The neonatal weight and incidence of macrosomia of the intervention group were lower than that of the control group, and the difference was statistically significant (P < 0.05).</p><p><strong>Conclusions: </strong>This study combined the individualized and continuous pregnancy weight management of the online WeChat platform and offline consultation based on the Fogg behavior model, showing great potential in improving maternal and infant outcomes.</p><p><strong>Trial registration: </strong>The study was registered with www.chictr.org.cn/index.aspx , Chinese Clinical Trial Registry (ChiCTR2200066707, 2022-12-14, retrospectively registered).</p>","PeriodicalId":9033,"journal":{"name":"BMC Pregnancy and Childbirth","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11289958/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141854735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Seroprevalence of hepatitis B virus and hepatitis C virus infection among pregnant women attending antenatal care at Guhala Primary Hospital, Northwestern Ethiopia. 在埃塞俄比亚西北部古哈拉初级医院接受产前检查的孕妇中乙型肝炎病毒和丙型肝炎病毒感染的血清流行率。
IF 2.8 2区 医学
BMC Pregnancy and Childbirth Pub Date : 2024-07-29 DOI: 10.1186/s12884-024-06714-6
Debaka Belete, Engidayehu Fekadie, Melkamu Kassaw, Melaku Fenta, Azanu Jegnie, Tigist Mulu, Gashaw Adane, Wondwossen Abebe, Azanaw Amare
{"title":"Seroprevalence of hepatitis B virus and hepatitis C virus infection among pregnant women attending antenatal care at Guhala Primary Hospital, Northwestern Ethiopia.","authors":"Debaka Belete, Engidayehu Fekadie, Melkamu Kassaw, Melaku Fenta, Azanu Jegnie, Tigist Mulu, Gashaw Adane, Wondwossen Abebe, Azanaw Amare","doi":"10.1186/s12884-024-06714-6","DOIUrl":"10.1186/s12884-024-06714-6","url":null,"abstract":"<p><strong>Background: </strong>Hepatitis B virus (HBV) and Hepatitis C Virus (HCV) infections are global issues that disproportionately affect developing countries. Pregnancy-related HBV and HCV infections are associated with a high risk of vertical transmission and complications for the mother as well as the newborn. Therefore, this study aims to determine the seroprevalence of hepatitis B virus and hepatitis C virus infection among pregnant women attending antenatal care at Guhala Primary Hospital, Northwestern Ethiopia.</p><p><strong>Methods: </strong>A hospital-based retrospective study was conducted from July to September 2022 on HBV and HCV registered books from September 1, 2017, to August 30, 2019, for a year. The presence of HBsAg and anti-HCV in serum was detected using the One Step Cassette Style HBsAg and anti-HCV antibody test kit. Data were analyzed using SPSS version 26 software.</p><p><strong>Results: </strong>In this study, a total of 2252 participants for HBsAg and 538 participants for ant-HCV rapid tests of records in the laboratory logbook were included. The mean age of the study participants was 25.6years (± 5.8SD). The overall prevalence of HBsAg and anti-HCV was 6.0% (134/2252) and 2.4% (13/538), respectively. There were 0.4% (2/538) coinfection results between HBV and HCV among pregnant women.</p><p><strong>Conclusion and recommendation: </strong>In this study, intermediate seroprevalence of HBV and HCV infection was detected among pregnant women attending antenatal care. The Hepatitis B virus was predominantly higher among pregnant women aged between 25 and 34 years. To manage and stop the potential vertical transmission of these viral agents during the early stages of pregnancy, routine prenatal testing for HBV and HCV infections should be taken into consideration.</p>","PeriodicalId":9033,"journal":{"name":"BMC Pregnancy and Childbirth","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11285531/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141791813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors affecting the quality of life in pregnant women with diabetes: the mediating effect of illnesses acceptance. 影响糖尿病孕妇生活质量的因素:疾病接受度的中介效应。
IF 2.8 2区 医学
BMC Pregnancy and Childbirth Pub Date : 2024-07-29 DOI: 10.1186/s12884-024-06690-x
Azita Fathnezhad-Kazemi, Zahra Seifinadergoli, Mohaddeseh Ahmadi
{"title":"Factors affecting the quality of life in pregnant women with diabetes: the mediating effect of illnesses acceptance.","authors":"Azita Fathnezhad-Kazemi, Zahra Seifinadergoli, Mohaddeseh Ahmadi","doi":"10.1186/s12884-024-06690-x","DOIUrl":"10.1186/s12884-024-06690-x","url":null,"abstract":"<p><strong>Introduction: </strong>Gestational diabetes, as a disorder of carbohydrate metabolism, is considered one of the most common metabolic complications in pregnancy. The diagnosis of diabetes in pregnancy leads to changes in lifestyle, and the treatments employed can affect various aspects of pregnant women's lives, including their quality of life. The present study aimed to investigate the relationship between self-efficacy and the mediating effect of illness acceptance on the quality of life in pregnant women diagnosed with diabetes during pregnancy.</p><p><strong>Materials and methods: </strong>This cross-sectional study was conducted on 240 pregnant women diagnosed with diabetes who were selected by convenience sampling method. Quality of life tools (SF12), the Acceptance of Illness Scale (AIS), and the Sherer self-efficacy scale were used to collect data.</p><p><strong>Results: </strong>The mean (SD) of quality of life, self-efficacy, and disease acceptance were 57.36 (6.63), 51.75 (7.44), and 29.07 (7.69), respectively. In the single-variable regression analysis, self-efficacy and disease acceptance variables could predict 20.6% (β = 0.457, P < 0.001) and 14.4% (β = 0.385, P < 0.001) of the variations in quality of life, respectively. In the multiple regression model, by entering the two main variables (self-efficacy and Acceptance of Illness), demographic characteristics, three disease knowledge variables, health status from an individual perspective, and type of treatment, the variables could explain 25% of the changes of the quality of life (R<sup>2</sup><sub>adj</sub> 0.25, P < 0.001=). Income status and self-efficacy had the highest impact among the variables. According to the results of path analysis, the total effect of self-efficacy on the quality of life of pregnant women with diabetes was 0.711.</p><p><strong>Conclusion: </strong>The overall quality of life in women with diabetes was moderate, and self-efficacy, illness acceptance, and income status were predictors of overall quality of life. Self-efficacy can influence the quality of life by affecting disease acceptance. The findings highlight the importance of designing educational programs and providing midwifery services to increase self-efficacy and illness acceptance to improve the quality of life of pregnant women with diabetes.</p>","PeriodicalId":9033,"journal":{"name":"BMC Pregnancy and Childbirth","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11285530/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141791864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oscillating autonomy: a grounded theory study of women's experiences of COVID-19 infection during pregnancy, labour and birth, and the early postnatal period. 摆动的自主权:对妇女在怀孕、分娩和产后早期感染 COVID-19 的经历进行的基础理论研究。
IF 2.8 2区 医学
BMC Pregnancy and Childbirth Pub Date : 2024-07-29 DOI: 10.1186/s12884-024-06685-8
Lili Peterson, Laura Bridle, Tisha Dasgupta, Abigail Easter, Stephanos Ghobrial, Irem Ishlek, Laura A Magee, Amanda Mansfield, Ismini Panayotidis, Hannah Rosen O'Sullivan, Panicos Shangaris, Anita Banerjee, Sergio A Silverio
{"title":"Oscillating autonomy: a grounded theory study of women's experiences of COVID-19 infection during pregnancy, labour and birth, and the early postnatal period.","authors":"Lili Peterson, Laura Bridle, Tisha Dasgupta, Abigail Easter, Stephanos Ghobrial, Irem Ishlek, Laura A Magee, Amanda Mansfield, Ismini Panayotidis, Hannah Rosen O'Sullivan, Panicos Shangaris, Anita Banerjee, Sergio A Silverio","doi":"10.1186/s12884-024-06685-8","DOIUrl":"10.1186/s12884-024-06685-8","url":null,"abstract":"<p><strong>Background: </strong>Testing positive for COVID-19 was associated with higher rates of detrimental psycho-social and physical health outcomes. The COVID-19 pandemic caused unprecedented disruption to everyday life. This included major reconfiguration of maternal, child, and perinatal mental health and care services and provision. This study aimed to investigate the experiences of those who tested positive for COVID-19 during pregnancy, labour and birth, or the early postnatal period.</p><p><strong>Methods: </strong>National on-line recruitment from across the United Kingdom resulted in sixteen mothers being invited to qualitative semi-structured interviews to understand the experiences of mothers who had been infected by COVID-19 during pregnancy, labour and birth, or the early postnatal period. Interviews were conducted, recorded, and transcribed using video-conferencing software. A Grounded Theory approach was used to analyse the data gathered pertaining to women's experiences of their positive COVID-19 diagnosis during pregnancy, labour and birth, or the early postnatal period.</p><p><strong>Results: </strong>The theory of 'Oscillating Autonomy - Losing and Seeking to Regain Control by Striving for Agency' was developed, comprising three main themes: 'Anxious Anticipation: The fear of infection was worse than COVID-19 itself'; 'Fluctuating Agency: What changed when COVID-19 took control'; and 'Reclaiming Control: Seeking reassurance during COVID-19 positivity'. Testing positive for COVID-19 whilst pregnant, during labour or birth, or in the early postnatal period was associated with a perceived loss of control. Those who were able to regain that control felt more secure in their situation.</p><p><strong>Conclusions: </strong>Support was paramount to manage increased vulnerability, as was reassurance achieved by information seeking and positive action including increased health monitoring and COVID-19 vaccination.</p>","PeriodicalId":9033,"journal":{"name":"BMC Pregnancy and Childbirth","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11285433/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141791865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between maternal lipid profiles and lipid ratios in early to middle pregnancy as well as their dynamic changes and gestational diabetes mellitus. 孕早期和孕中期母体血脂概况和血脂比率及其动态变化与妊娠糖尿病之间的关系。
IF 2.8 2区 医学
BMC Pregnancy and Childbirth Pub Date : 2024-07-29 DOI: 10.1186/s12884-024-06692-9
Xingyan Xu, Suping Luo, Jie Lin, Jungu Zhou, Liuyan Zheng, Le Yang, Zhiyu Zhang, Yuting Dong, Mei Ma, Huangyuan Li, Shaowei Lin, Xiaoxu Xie, Jinying Luo, Siying Wu
{"title":"Association between maternal lipid profiles and lipid ratios in early to middle pregnancy as well as their dynamic changes and gestational diabetes mellitus.","authors":"Xingyan Xu, Suping Luo, Jie Lin, Jungu Zhou, Liuyan Zheng, Le Yang, Zhiyu Zhang, Yuting Dong, Mei Ma, Huangyuan Li, Shaowei Lin, Xiaoxu Xie, Jinying Luo, Siying Wu","doi":"10.1186/s12884-024-06692-9","DOIUrl":"10.1186/s12884-024-06692-9","url":null,"abstract":"<p><strong>Background: </strong>Unfavourable lipid and glucose levels may play a crucial role in the pathogenesis of gestational diabetes mellitus (GDM). However, there is a lack of prospective studies on the relationship between lipid profiles, lipid ratios and GDM during pregnancy.</p><p><strong>Aims: </strong>To prospectively investigate the relationship between lipid profile and lipid ratios in early and mid-pregnancy and their pattern of change from early to mid-pregnancy and the risk of GDM.</p><p><strong>Methods: </strong>This nested case-control study was based on maternal and child healthcare hospitals from Fujian Province, China. We included pregnant women who delivered in the hospital from January 2021 to June 2023. Lipid profiles (TC, TG, ApoA1, ApoB, HDL-c, LDL-c) and fasting glucose were measured before 14 weeks of gestation and between 20 and 28 weeks of gestation, and lipid ratios (triglyceride glucose index, TG/HDL-c and TC/HDL-c) was constructed. Logistic regression was used to assess the relationship between lipid profile, lipid ratios and GDM.</p><p><strong>Results: </strong>Of 1586 pregnant women, 741 were diagnosed with GDM. After adjusting for potential confounders, TG, ApoA1, ApoB, LDL-c, triglyceride glucose index, TG/HDL-c, and TC/HDL-c in early pregnancy were positively associated with the risk of GDM (odds ratios [95% CI] for extreme interquartile comparisons were 2.040 (1.468-2.843), 1.506 (1.091-2.082), 1.529 (1.110-2.107), 1.504 (1.086-2.086), 1.952 (1.398-2.731), 2.127 (1.526-2.971), and 2.370 (1.700-3.312), all trend P < 0.05). HDL-c was negatively associated with the risk of GDM (0.639: 0.459-0.889, trend P all less than 0.05). Similarly, in mid-pregnancy, lower levels of HDL-c, higher levels of triglyceride glucose index, TG/HDL-c ratio, and TC/HDL-c ratio were associated with increased risk of GDM (all trends P < 0.05). Stably high levels (both ≥ median for early and mid-pregnancy) of triglyceride glucose index, TG/HDL-c and TC/HDL-c were associated with increased risk of GDM (OR [95% CI]: 2.369 (1.438-3.940), 1.588 (1.077-2.341), 1.921 (1.309-2.829), respectively). The opposite was true for HDL-c, where stable high levels were negatively associated with GDM risk (OR [95% CI]: 0.599 (0.405-0.883)).</p><p><strong>Conclusion: </strong>Increases in triglyceride glucose index, TG/HDL-c ratio, and TC/HDL-c ratio in early and mid-pregnancy, as well as their stable high levels from early to mid-pregnancy, are associated with a higher risk of GDM. In contrast, increased levels of HDL-c, both in early and mid-pregnancy, and their stable high levels from early to mid-pregnancy were associated with a lower risk of GDM. That highlighted their possible clinical relevance in identifying those at high risk of GDM.</p>","PeriodicalId":9033,"journal":{"name":"BMC Pregnancy and Childbirth","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11285337/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141791863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of perinatal anxiety assessment measures: a cognitive interview study 围产期焦虑评估措施的评估:认知访谈研究
IF 3.1 2区 医学
BMC Pregnancy and Childbirth Pub Date : 2024-07-27 DOI: 10.1186/s12884-024-06641-6
Rose Meades, Andrea Sinesi, Louise R. Williams, Amy Delicate, Helen Cheyne, Margaret Maxwell, Fiona Alderdice, Julie Jomeen, Judy Shakespeare, Cassandra Yuill, Susan Ayers
{"title":"Evaluation of perinatal anxiety assessment measures: a cognitive interview study","authors":"Rose Meades, Andrea Sinesi, Louise R. Williams, Amy Delicate, Helen Cheyne, Margaret Maxwell, Fiona Alderdice, Julie Jomeen, Judy Shakespeare, Cassandra Yuill, Susan Ayers","doi":"10.1186/s12884-024-06641-6","DOIUrl":"https://doi.org/10.1186/s12884-024-06641-6","url":null,"abstract":"Anxiety in pregnancy and postpartum is highly prevalent but under-recognised. To identify perinatal anxiety, assessment tools must be acceptable, relevant, and easy to use for women in the perinatal period. To determine the acceptability and ease of use of anxiety measures to pregnant or postpartum women (n = 41) we examined five versions of four measures: the Generalised Anxiety Disorder scale (GAD) 2-item and 7-item versions; Whooley questions; Clinical Outcomes in Routine Evaluation (CORE-10); and Stirling Antenatal Anxiety Scale (SAAS). Cognitive interviews were used to examine ease of comprehension, judgement, retrieval and responding. All measures were acceptable. Some items were deemed less relevant to the perinatal period e.g., difficulties sleeping. Ease of comprehension, judgement, retrieval and responding varied, with all measures having strengths and weaknesses. The SAAS and CORE-10 had the lowest mean number of problematic components. The GAD had the highest mean number of problematic components​. Non-binary response options were preferred. Preferences for time frames (e.g. one week, one month) varied. Qualitative data provides in-depth information on responses to each measure. Findings can be used to inform clinical guidelines and research on acceptable anxiety assessment in pregnancy and after birth.\u0000","PeriodicalId":9033,"journal":{"name":"BMC Pregnancy and Childbirth","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141774127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Obstetric interventions’ effects on the birthing experience 产科干预对分娩体验的影响
IF 3.1 2区 医学
BMC Pregnancy and Childbirth Pub Date : 2024-07-27 DOI: 10.1186/s12884-024-06626-5
Anna Volkert, Lisa Bach, Carsten Hagenbeck, Jan Kössendrup, Charlotte Oberröhrmann, Mi-Ran Okumu, Nadine Scholten
{"title":"Obstetric interventions’ effects on the birthing experience","authors":"Anna Volkert, Lisa Bach, Carsten Hagenbeck, Jan Kössendrup, Charlotte Oberröhrmann, Mi-Ran Okumu, Nadine Scholten","doi":"10.1186/s12884-024-06626-5","DOIUrl":"https://doi.org/10.1186/s12884-024-06626-5","url":null,"abstract":"The birth experience plays a pivotal role in the mother´s mental well-being and has a crucial effect on the mother-child bond. Unanticipated medical interventions, including fundal pressure, episiotomy, assisted vaginal delivery (AVD), or unplanned cesarean section (CS) during labor, may adversely affect the birth experience. The objective of this study is to identify factors contributing to the diminished evaluation of the birth experience after assessing the prevalence of unplanned obstetrical interventions in Germany. For this cross-sectional analysis, 4000 mothers whose children were born 8 or 12 months before were asked about their birth experience via a paper-based questionnaire. Overall 1102 mothers participated in the study, representing a response rate of 27.6%. The revised Childbirth Experience Questionnaire (CEQ2) was used to measure the childbirth experience. In addition to descriptive and bivariate analyses using the Wilcoxon rank-sum test and Kruskal-Wallis-test, we calculated multivariate linear regression models for each dimension of the CEQ2. In general, the participants evaluated their childbirth experience favorably, assigning an average rating of 3.09 on a scale ranging from 1 to 4. Women who experienced fundal pressure, an AVD, or an unplanned CS rated their birth experience significantly worse compared to women who gave birth without interventions. Unplanned CSs received the lowest ratings for “personal capability” and “perceived safety,” and an AVD resulted in lower scores for “professional support” and “participation.” However, the interventions we studied did not account for much of the variation in how the childbirth experience plays out for different individuals. Obstetric interventions have a significant effect on different dimensions of the birth experience. If a high level of birth satisfaction is to be achieved, it is important to know which dimension of satisfaction is affected by the intervention so that explicit measures, like fostering communication, participation or safety can be taken to promote improvement. DRKS00029214, retrospectively registered (Registration Date 22.06.2023).","PeriodicalId":9033,"journal":{"name":"BMC Pregnancy and Childbirth","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141774125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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