BMC Pregnancy and Childbirth最新文献

{"title":"Exploring adherence to iron and folic acid supplementation in pregnant women at rural health facilities in Waghimra zone, Northern Ethiopia.","authors":"Mohammed Abdu Seid, Aster Shumet Gebru, Ali Yimer, Kedir Ali, Adem Yesuf, Nurye Sirage, Abubeker Seid, Natnael Amare Tesfa, Hassen Ahmed","doi":"10.1186/s12884-025-08119-5","DOIUrl":"10.1186/s12884-025-08119-5","url":null,"abstract":"<p><strong>Background: </strong>Iron deficiency anemia is a prevalent condition during pregnancy, particularly in resource-limited areas, and is associated with negative fetal and maternal outcomes. A key strategy to prevent anemia during pregnancy involves ensuring adequate iron and folic acid supplementation (IFAS), diversifying the diet, deworming and infections control, such as malaria. This study aimed to assess the extent to which pregnant women at rural health facilities adhere to IFAS and to identify the factors contributing to this adherence.</p><p><strong>Methods: </strong>A multi-center cross-sectional study was conducted from February to June 2024 at rural health facilities in Ethiopia. Systematic random sampling was used to recruit study participants, and data were collected through semi-structured questionnaires, client interviews, and document reviews. The data were entered into Epi-Data 4 and then exported to STATA-16 for analysis. To explore the association between outcome and independent variables, both bi-variable and multivariable logistic regression models were applied. After performing multivariable regression, variables with a p-value < 0.05 were considered statistically significant.</p><p><strong>Results: </strong>Four hundred and six pregnant women were study participants. The mean age of the pregnant women was 27.9 years (SD ± 7.1). Adherence to IFAS was 45.1% [95% CI: 40.3-49.9%]. Counseling on the importance of IFAS (AOR = 2.29; 95% CI: 1.21-4.34), number of antenatal care (ANC) contacts (AOR = 3.50; 95% CI: 1.54-7.92), good knowledge of IFAS (AOR = 4.22; 95% CI: 2.43-7.31), and anemia (AOR = 3.07; 95% CI: 1.36-6.89) were associated factors.</p><p><strong>Conclusions: </strong>The adherence of pregnant women to IFAS was very low compared to the world health organization recommendation (45% vs. > 80%). Counseling regarding the importance of IFAS, the number of ANC contacts, good knowledge of IFAS, and anemia status were independent predictors. Creating awareness about IFAS, providing counseling during ANC contacts, and strengthening the monitoring and evaluation system are all critically important.</p>","PeriodicalId":9033,"journal":{"name":"BMC Pregnancy and Childbirth","volume":"25 1","pages":"1060"},"PeriodicalIF":2.7,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12512253/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145257195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Failed induction of labor and associated factors among women receiving induction at public hospitals of Kembata zone in central Ethiopia.","authors":"Arega Abebe Lonsako, Teshale Tilahun, Mulatu Wolde, Tariku Laelago, Tsehaynew Kasse, Asfaw Anulo, Addisu Girma","doi":"10.1186/s12884-025-08103-z","DOIUrl":"10.1186/s12884-025-08103-z","url":null,"abstract":"<p><strong>Background: </strong>Failed induction of labour contributes to high caesarean section rates, posing risks to both maternal and neonatal health. Despite its clinical importance, limited data exists on the prevalence and determinants of failed induction of labour in Ethiopia. Therefore, this study aimed to assess the prevalence and determinants of failed induction of labour among women in public hospitals of central Ethiopia.</p><p><strong>Methods: </strong>A retrospective cross-sectional study was conducted across multiple health facilities. Data were extracted from the 386 randomly selected medical charts using a pre-tested checklist, then entered into Epi data version 3.1 and exported to SPSS version 26 for analysis. Multivariable Logistic regression analysis was performed and statistical significance was declared at p < 0.05.</p><p><strong>Results: </strong>The prevalence of failed labor induction was 21.2%, with a 95% confidence interval (CI) of 17-25%. Factors significantly associated with failed induction included age over 30 years [adjusted odds ratio (AOR) = 6.78, 95% CI: 3.13-14.70], being a primigravida [AOR = 6.68, 95% CI: 3.10-14.40], a low Bishop score [AOR = 3.90, 95% CI: 1.62-9.39], and premature rupture of membranes [AOR = 3.27, 95% CI: 1.42-7.54].</p><p><strong>Conclusion: </strong>The study identified a high rate of failed labour induction. Key factors contributing to failed labour induction included maternal age over 30 years, primigravida status, a low Bishop score, and premature rupture of membranes. Enhanced monitoring and follow-up are necessary to mitigate potential adverse effects on both maternal and fetal health.</p>","PeriodicalId":9033,"journal":{"name":"BMC Pregnancy and Childbirth","volume":"25 1","pages":"1059"},"PeriodicalIF":2.7,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12512734/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145257237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Newborn postnatal care: gap in contact and effective coverage and discrepancy in response in Ethiopia.","authors":"Melash Belachew Asresie, Anteneh Mengist Dessie","doi":"10.1186/s12884-025-08143-5","DOIUrl":"10.1186/s12884-025-08143-5","url":null,"abstract":"","PeriodicalId":9033,"journal":{"name":"BMC Pregnancy and Childbirth","volume":"25 1","pages":"1042"},"PeriodicalIF":2.7,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12505721/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145249545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of co administration of gonadotropins and letrozole during the ovarian stimulation on IVF outcome for poor responders: a systematic review and meta-analysis of randomized controlled trials.","authors":"Faezeh Zakerinasab, Mersad Khalili, Fatemeh AbdollahyBiroon, Qumars Behfar, Reza Parsaee, Mahdis Sadat Miri, Arina Ansari, Fariba Arbab Mojeni, Niloofar Deravi, Ramina Fazeli, Mobina Fathi","doi":"10.1186/s12884-025-08127-5","DOIUrl":"10.1186/s12884-025-08127-5","url":null,"abstract":"<p><strong>Background: </strong>Letrozole utilizing, an aromatase inhibitor, has been examined to improve pregnancy rate in poor ovarian response women. Increasing the dose of gonadotropins and enhancement of follicles' sensitivity to androgens, are the possible mechanism of letrozole. This meta-analysis aimed to evaluate the effect of co-administration of letrozole and gonadotropin on IVF/ICSI outcomes in poor ovarian response women.</p><p><strong>Method: </strong>Relevant randomized controlled trials were obtained through search in several databases including PubMed, Scopus, Clinicaltrials.gov, Google scholar, and Cochrane Library. The RCTs investigating the effect of letrozole + gonadotropin versus gonadotropin reporting pregnancy outcome were selected.</p><p><strong>Results: </strong>After analyzing 13 RCTs comprising 1692 patients, letrozole was associated with a reduction in the dose (SMD: -147.96 (-180.49, -115.42), P < 0.01) and duration (SMD: -2.82 (-4.21, -1.42), P < 0.01 of gonadotropin administration. There was no evidence of a difference between groups in the number of retrieved oocytes, clinical pregnancy rate, or live birth rate. A small reduction in the number of transferred embryos was observed (SMD: -0.26 (-0.49, -0.02), P = 0.03), though this finding should be interpreted with caution given heterogeneity across studies. Overall, no significant improvement in reproductive outcomes was demonstrated.</p><p><strong>Conclusions: </strong>Despite the lack of significant improvement in pregnancy and live birth rate in the letrozole group, the dose and duration of gonadotropins decreased. This has the potential to reduce the side effects of gonadotropins. However, further studies are necessary to confirm its safety and whether its use translates into clinically meaningful benefits.</p>","PeriodicalId":9033,"journal":{"name":"BMC Pregnancy and Childbirth","volume":"25 1","pages":"1046"},"PeriodicalIF":2.7,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12506345/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145249505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiomics-based correlation analysis of fetal brain MRI features and children's neurodevelopmental outcomes in monochorionic twins.","authors":"Huina Lai, Yingnan Ye, Yiqing Chen, Liqin Wang, Minhuan Lin, Shuting Xia, Zhiming He, Xuan Huang, Kaniok You, Xuewen Huang, Miao Fan, Linhuan Huang, Yanmin Luo","doi":"10.1186/s12884-025-08214-7","DOIUrl":"10.1186/s12884-025-08214-7","url":null,"abstract":"<p><strong>Objective: </strong>To characterize fetal brain MRI features in monochorionic twin pregnancies based on radiomics; and to investigate the correlation between these radiomic features and subsequent neurodevelopmental outcomes.</p><p><strong>Methods: </strong>This retrospective cohort study analyzed 26 monochorionic twin pregnancies (36 fetus included) who underwent fetal brain MRI (Siemens Magnetom Skyra 3.0 T or Philips Ingenia 3.0 T). Neurodevelopmental assessment categorized 20 monochorionic twins into the good neurodevelopmental group and 16 into the moderate neurodevelopmental group. MRI textural features of different brain areas were quantified by composite radiomics score and individual radiomics-feature score, and the correlation between these scores and neurodevelopmental outcomes during postnatal follow-up was analyzed.</p><p><strong>Results: </strong>Quantitative radiomic analysis revealed significantly higher radiomics score in the good neurodevelopmental group for the following regions: periventricular white matter (PWM), frontal, parietal and temporal lobes (all P < 0.05). Four specific radiomics-feature score demonstrated significant group differences in these regions: Gray Level Dependence Matrix (GLDM) in PWM, first-order statistical feature in frontal lobe, Gray Level Size Zone Matrix (GLSZM) in parietal lobe, and GLSZM in temporal lobe. For predictive modeling, we identified five high-discriminatory features representing distinct feature categories: shape features (Elongation), first-order statistical features (Kurtosis), and texture features (GLCM: Cluster Shade, GLRLM: Long Run High Gray Level Emphasis, GLSZM: Size Zone Non Uniformity). The logistic regression model with nested cross-validation incorporating these features achieved excellent predictive performance for neurodevelopmental outcomes [Mean of AUC = 0.8900 (± 0.1133)].</p><p><strong>Conclusions: </strong>Radiomics scores were higher in good neurodevelopmental fetuses, and the selected radiomics features may be helpful for predicting the neurodevelopmental outcomes of monochorionic twins.</p>","PeriodicalId":9033,"journal":{"name":"BMC Pregnancy and Childbirth","volume":"25 1","pages":"1040"},"PeriodicalIF":2.7,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12505796/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145249571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trend of malaria test positivity rate among pregnant women, Savannah Region, Ghana, 2018-2022.","authors":"Wadeyir Jonathan Abesig, Joseph Alphonsus Chantiwuni Nindow, Annungma C Bagonluri, Adjei Kwabena Sarfo, Gyesi Razak Issahaku, Magdalene Akos Odikro, George Akowuah, Delia Akosua Bandoh, Ernest Kenu, Chrysantus Kubio","doi":"10.1186/s12884-025-08157-z","DOIUrl":"10.1186/s12884-025-08157-z","url":null,"abstract":"<p><strong>Background: </strong>Malaria in pregnancy (MiP) remains a serious public health problem due to its adverse effects on maternal health, pregnancy outcomes, and the cost of healthcare delivery. Significant successes have been achieved in controlling malaria globally. However, little is known about the progress made in controlling malaria in pregnancy in the Savannah Region. We described the trend of the MiP test positivity rate in the Savannah Region of Ghana from 2018 to 2022.</p><p><strong>Methods: </strong>The study employed a retrospective, descriptive, cross-sectional study using data from 2018 to 2022. Data on malaria in pregnancy in the Savannah Region was extracted from the DHIMS 2 database and transferred into Microsoft Excel version 19. Descriptive statistical analyses were done. Results were summarised into frequencies and percentages and presented in tables, graphs, and maps.</p><p><strong>Results: </strong>Overall, the MiP testing rate was 90.8% (46,734/51,479) and 54.5% (95% CI: 54.0-55.0) of pregnant women tested positive. The majority, 68.0%, of MiP cases in the region were mothers aged 20-34 years. However, the MiP test positivity rate was highest among mothers aged below 20 years, 59.3% (95% CI: 58.1-60.6). Bole District had the highest MiP test positivity rate, 70.1% (95% CI: 69.3-70.8) and accounted for 40.5% (10,315/25,463) of all MiP cases. There was a decline in the MiP test positivity rate from 2018 to 2022 from 60.4% (95% CI: 59.3-61.5) to 51.6% (95% CI: 50.7-52.6).</p><p><strong>Conclusion: </strong>The MiP test positivity rate in the Savannah Region is high, with disparities among Districts. However, there is an apparent decline over the study period. There is a need to strengthen existing malaria prevention interventions in pregnancy, such as the use of SP for IPTp and ITNs to prevent negative maternal and fetal birth outcomes. Public health education programmes could improve the uptake and utilisation of ITNs. Further research should be conducted to unravel the reasons for the disproportionately high MiP test positivity rate in the Bole District to enable the implementation of preventive measures.</p>","PeriodicalId":9033,"journal":{"name":"BMC Pregnancy and Childbirth","volume":"25 1","pages":"1051"},"PeriodicalIF":2.7,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12505843/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145249574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is postpartum preeclampsia a continuation of intrapartum preeclampsia? Maternal risk factors in intrapartum vs. postpartum preeclampsia: a retrospective cohort study.","authors":"Hila Shalev-Ram, Talish Razi, Dorit Ravid, Hezzy Shmueli, Ronen Arbel, Tal Biron-Shental","doi":"10.1186/s12884-025-08227-2","DOIUrl":"10.1186/s12884-025-08227-2","url":null,"abstract":"","PeriodicalId":9033,"journal":{"name":"BMC Pregnancy and Childbirth","volume":"25 1","pages":"1048"},"PeriodicalIF":2.7,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12505748/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145249565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between fetal tissue chromosomal karyotype and clinical characteristics in patients with spontaneous abortion: a retrospective study.","authors":"Lin Liu, Yanting Yang, Huyan Huo, Ning Hu, Fang Wang","doi":"10.1186/s12884-025-08106-w","DOIUrl":"10.1186/s12884-025-08106-w","url":null,"abstract":"<p><strong>Background: </strong>Abnormal fetal tissue chromosome karyotypes are one of the important pathogenic factors for spontaneous abortion (SA). To analyze the characteristics of fetal tissue chromosomal karyotype in 778 women with a history of SA and its relationship with clinical features.</p><p><strong>Methods: </strong>A retrospective study collected maternal age, body mass index (BMI), gestational weeks at miscarriage, the number of previous pregnancy losses and fetal tissue karyotypes CNV-seq data of 778 SA couples from Lanzhou University Second Hospital from October 2019 to December 2023, and described the characteristics of fetal tissue chromosomal karyotype and its relationship with clinical features.</p><p><strong>Results: </strong>In our study, 432 patients (55.53% of total) had abnormal fetal tissue chromosomal karyotypes, with the highest incidence being trisomy syndrome (46.99%, 203/432). Advanced maternal age (> 35 years), early pregnancy (< 12 weeks), and a history of less than four previous pregnancy losses were all identified as risk factors for fetal tissue chromosomal abnormalities.</p><p><strong>Conclusion: </strong>The results of this study indicate that fetal tissue chromosomal abnormalities are the primary factor leading to SA. Additionally, advanced maternal age (> 35years), early pregnancy (< 12 weeks), and the fewer number of previous pregnancy losses (≤ 4 times) are associated with a higher risk of fetal tissue chromosomal abnormalities following miscarriage.</p>","PeriodicalId":9033,"journal":{"name":"BMC Pregnancy and Childbirth","volume":"25 1","pages":"1043"},"PeriodicalIF":2.7,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12506309/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145249591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Elevated maternal serum aminotransferase in early pregnancy associated with early-onset preeclampsia: A cohort study of 116,967 pregnancies in Shanghai, China.","authors":"Shutian Zhang, Jinwen Zhang, Yulai Zhou, Jing Zhu, Juan Li, Yunyun Cao, Li Li, Yanlin Wang, Weibin Wu","doi":"10.1186/s12884-025-08107-9","DOIUrl":"10.1186/s12884-025-08107-9","url":null,"abstract":"<p><strong>Induction: </strong>Preeclampsia (PE) is a severe pregnancy-specific complications along with multiple organ impairment. However, whether women with elevated serum aminotransferase levels in early pregnancy are susceptible to PE, and even early-onset PE remains unclear.</p><p><strong>Materials and methods: </strong>A hospital-based retrospective cohort study involving 116,967 pregnant women delivered between 2014 and 2022 in Shanghai, China was conducted. The study employed restricted cubic splines and logistic regression analysis to investigate the associations between early maternal liver function tests, specifically alanine aminotransferase (ALT), aspartate aminotransferase (AST), and the ALT/AST ratio, and the risk of PE and its subtypes, including early-onset preeclampsia (occurred at < 34 weeks of gestation) and late-onset preeclampsia (occurred at ≥ 34 weeks of gestation).</p><p><strong>Results: </strong>Elevated ALT levels (> 40 IU/L) in early pregnancy were associated with an increased risk of PE (adjusted odds ratio (aOR) = 1.57 [95% confidence interval (CI): 1.38-1.80]), early-onset PE (aOR = 1.78 [95% CI: 1.27-2.48]) and late-onset PE (aOR = 1.53 [95% CI: 1.33-1.76]). Increased risks of PE and early-onset PE were also observed in pregnant women with AST levels > 40 IU/L (aOR = 1.63 [95% CI: 1.33-1.99] for PE; aOR = 1.81 [95% CI: 1.09-3.00] for early-onset PE ) or ALT/AST ratio > 1 (aOR = 1.36 [95% CI: 1.25-1.47] for PE; aOR = 1.66 [95% CI: 1.34-2.06] for early-onset PE). Furthermore, women with abnormal ALT or AST levels in early pregnancy but relieved in later pregnancy periods still had elevated risks of PE and early-onset PE. The stratified analysis demonstrated that women with advanced age complicated with high ALT have increased risk of developing early-onset PE.</p><p><strong>Conclusions: </strong>Elevated levels of ALT, AST and their ratios in early pregnancy were associated with an increased risk of PE, especially early-onset PE. Therefore, screening for aminotransferase levels in early pregnancy could be considered for identification of women at high risk of developing liver dysfunction-related PE, or even early-onset PE.</p>","PeriodicalId":9033,"journal":{"name":"BMC Pregnancy and Childbirth","volume":"25 1","pages":"1052"},"PeriodicalIF":2.7,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12505622/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145249526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal and infant outcomes of pregnancy anemia at one month postpartum: a cohort analysis.","authors":"Lucienne Zinsstag, Souliviengkham Sonephet, Jessica Rigutto-Farebrother, Somphou Sayasone, Günther Fink, Jordyn T Wallenborn","doi":"10.1186/s12884-025-08137-3","DOIUrl":"10.1186/s12884-025-08137-3","url":null,"abstract":"<p><p>BACKGROUND AND OBJECTIVES: Postpartum anemia is a significant public health concern affecting both maternal and infant health. This study aimed to investigate the relationship between maternal anemia during pregnancy, and infant anthropometric measurements at one month postpartum, as well as postpartum anemia in mothers and infants.</p><p><strong>Methods: </strong>Data from the Social Transfer for Exclusive Breastfeeding (STEB) randomized controlled trial in Vientiane, Lao People's Democratic Republic (Lao PDR), were analyzed. Linear and logistic regression models were used to calculate adjusted estimates, including beta and odds ratios, and 95% confidence intervals (CI) for maternal hemoglobin (Hb) levels and anemic status during pregnancy and at one month postpartum. Primary outcomes were infant anthropometric measurements, with secondary outcomes including infant and maternal Hb levels and anemic status at one month postpartum.</p><p><strong>Results: </strong>At one month postpartum, we identified 298 mothers (mean age: 27 years) and their healthy term infants who were born at a healthy birth weight. No significant association was found between maternal anemic status (yes/no) and Hb levels during pregnancy and infant anthropometric measurements at one month postpartum. A positive association was observed between maternal and infant Hb levels at one month postpartum, with a 0.2 g/L increase in infant Hb for every 1 unit increase in maternal Hb (β = 0.23, 95% CI: 0.05, 0.40, p < 0.01).</p><p><strong>Conclusion: </strong>These findings highlight the importance of early postpartum intervention and continued nutritional care for both mothers and infants during the postpartum period, especially for mothers who experienced anemia during pregnancy. Further research is needed to explore the long-term effects of maternal postpartum health on infant development and growth.</p>","PeriodicalId":9033,"journal":{"name":"BMC Pregnancy and Childbirth","volume":"25 1","pages":"1039"},"PeriodicalIF":2.7,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12505624/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145249562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}