BMC Psychiatry最新文献

{"title":"Association of unhealthy lifestyles and suicidal behaviors among Chinese middle school students: a latent class analysis.","authors":"Chunyan Wang, Qiaoyue Wei, Wenwen Yin, Shuibo Pan, Chenyangzi Dai, Linhua Zhou, Xiaoyu Jiang, Hong Cai, Junduan Wu","doi":"10.1186/s12888-025-07009-6","DOIUrl":"https://doi.org/10.1186/s12888-025-07009-6","url":null,"abstract":"<p><strong>Background: </strong>The unhealthy lifestyles not only affect physical development of adolescents but are also closely related to various psychological problems. This article will examine potential classes of middle school students' lifestyles and explore the associations between lifestyles and suicidal behaviors.</p><p><strong>Methods: </strong>Data were collected from a cross-sectional survey of middle schools in five cities of Guangxi. A total of 5291 students completed the short questionnaire on suicidal behaviors and lifestyles. The latent class analysis was used to identify the unrecorded patterns of lifestyles. Multifactor logistic regression was used to explore the associations between health lifestyles and suicidal behaviors.</p><p><strong>Results: </strong>The three classes lifestyles were identified: Class1(8.0%) - high risk lifestyle group, Class2(18.6%)-high lack of exercise group, and Class3(73.5%) - low risk lifestyle group, respectively. Middle school students among Class 1 had higher odds than Class 3 (OR = 2.061, 95%CI = 1.474 ~ 2.882、OR = 3.323, 95%CI = 2.185 ~ 5.052 for self-injurious thoughts; OR = 2.008, 95%CI = 1.438 ~ 2.804、OR = 3.217, 95%CI = 2.125 ~ 4.868 for suicidal ideations; OR = 1.488, 95%CI = 1.063 ~ 2.081、OR = 2.718, 95%CI = 1.744 ~ 4.236 for self-injurious behaviors) for experiencing self-injurious thoughts, suicidal ideation, and self-injurious behaviors, whether occurring once, five times, or more, respectively. Class 2 were only more likely to engage in self-injurious behavior at once compared to Class 3(OR = 1.414, 95%CI = 1.110 ~ 1.800).</p><p><strong>Conclusions: </strong>This finding highlighted the importance of improving unhealthy lifestyles for preventing and intervening in suicidal behavior among middle school students. More actions for intervention in the lifestyles of students should be needed to ensure their physical and mental health.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"629"},"PeriodicalIF":3.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144538272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interconnectivity among different nonsuicidal self-injurious methods - a network analysis.","authors":"Melinda Reinhardt, Kenneth G Rice, Hunggu Cho, Zsolt Horváth","doi":"10.1186/s12888-025-07045-2","DOIUrl":"https://doi.org/10.1186/s12888-025-07045-2","url":null,"abstract":"<p><strong>Background: </strong>An important indicator of self-harm severity is the co-occurrence of different nonsuicidal self-injurious (NSSI) behaviors. However, there is little research on how different self-injurious behaviors (e.g., cutting, biting, burning, carving) are related. In contrast to person-centred approaches, variable-centred network analysis helps to identify the most meaningful associations between different forms of NSSI behavior, thus allowing the identification of structural patterns in different NSSI methods. Based on network analysis, it will be possible to examine which NSSI methods are the most central and which are most closely linked to other methods.</p><p><strong>Methods: </strong>We used network analysis to investigate interconnections between 12 different self-harm methods. The Inventory of Statements About Self-Injury [24] was utilized to assess the types and frequency of NSSI in a community adult sample.</p><p><strong>Results: </strong>More than one-third (39.7%; n = 744) of 1873 adults reported at least one episode of NSSI in their lifetime. Most (77%) of those engaged in NSSI used more than one NSSI method. The most frequently used NSSI methods were hitting self, interfering with wound healing, pinching, biting, and severe scratching. In the NSSI methods network analysis, severe scratching, cutting, and pinching had the highest rates of interrelationship with other NSSI behaviors. Moreover, the interconnectedness of certain specific NSSI-methods (i.e., cutting with burning and carving; severe scratching with pinching, biting and hitting self) have a greater risk of co-occurrence (versatility).</p><p><strong>Conclusions: </strong>Although different NSSI methods occurred as distinct entities, some play a more central role in the network. Our results suggest that the NSSI methods identified as central should be given more attention in clinical settings as these behaviors may indicate the severity of the condition. Specifically, when assessing and treating those who engage in self-harm, clinicians may find it useful to create a detailed map of the person-specific NSSI-methods to inform risk assessment and treatment.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"601"},"PeriodicalIF":3.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144538324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intractable prefrontal and limbic white matter network disruption in adolescents with drug-naïve nonsuicidal self-injury.","authors":"Yuwei Chen, Xiongxiong Yang, Kaike Liao, Rui Yu, Xinyue Chen, Wenjing Zhang, Nian Liu","doi":"10.1186/s12888-025-07106-6","DOIUrl":"https://doi.org/10.1186/s12888-025-07106-6","url":null,"abstract":"<p><strong>Background: </strong>The white matter network changes that accompany nonsuicidal self-injury (NSSI) among adolescents are not well understood. This study thus sought to investigate the structural connectivity and network features of adolescents with drug-naïve NSSI, while also evaluating the alterations in these parameters following treatment.</p><p><strong>Method: </strong>The diffusion tensor imaging and clinical scales were used to evaluate 43 adolescents with drug-naïve NSSI, 20 of them after treatment (post-treatment NSSI group), and 43 healthy controls (HC). Graph theory analyses were used to construct a white matter network consisting of 90 regions for these participants. Network-based statistic (NBS) correction methods were used to assess structural connectivity within this network, and a generalized linear model was used to compare network metrics between NSSI and HCs, whereas paired t-tests were used to compare the same patients pre- and post-treatment. Correlations between clinical symptoms and both structural connectivity and network metrics were assessed.</p><p><strong>Results: </strong>Greater structural connectivity was observed between the right caudate nucleus and right olfactory cortex, right superior frontal gyrus (medial orbital), and right amygdala in adolescents with drug-naïve NSSI relative to HCs. Adolescents with drug-naïve NSSI was also found with increased characteristic path length and normalized characteristic path length values in network metrics, and reduced global efficiency and nodal network metrics for the right orbital middle frontal gyrus, which were also negatively correlated with anxiety and self-injury symptoms. After treatment, post-treatment NSSI group exhibited network alterations that were most pronounced in the prefrontal lobes, left parahippocampal gyrus, and left middle occipital gyrus.</p><p><strong>Conclusions: </strong>These results offer new insight into the abnormal structural connectivity and network metrics that arise in the prefrontal gyrus and limbic system of adolescents with drug-naïve NSSI, potentially providing guidance for the interpretation of NSSI-related imaging changes in the white matter network.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"662"},"PeriodicalIF":3.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144538325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of premenstrual syndrome among students and the association of social media addiction with its severity in Hamadan: a cross-sectional study.","authors":"Seyedeh Fatemeh Mousavi, Samaneh Goudarz, Azin Latifi, Sima Fazli, Farideh Kazemi, Seyedeh Zahra Masoumi, Mansoureh Refaei","doi":"10.1186/s12888-025-07116-4","DOIUrl":"https://doi.org/10.1186/s12888-025-07116-4","url":null,"abstract":"<p><strong>Background: </strong>Considering that numerous adverse effects of social media addiction (SMA) share characteristics with premenstrual syndrome (PMS), this study aims to determine the prevalence of PMS and to investigate the relationship between SMA and the severity of PMS symptoms among students at Hamadan University of Medical Sciences.</p><p><strong>Methods: </strong>This descriptive-analytical cross-sectional study was conducted between 2023 and 2024, involving 380 students from Hamadan University of Medical Sciences situated within the university environment and its affiliated dormitories. Sampling was performed using a convenience approach, and participants who met the inclusion criteria completed demographic questionnaires, the Social Media Addiction Scale-Student Form (SMAS-SF), and the Premenstrual Symptoms Questionnaire (PSST). Data analysis was executed utilizing Stata version 13 statistical software, with a significance level set at less than 0.05.</p><p><strong>Results: </strong>The results indicated that 73.68% of the participants were experiencing PMS, while 7.11% were diagnosed with Premenstrual Dysphoric Disorder (PMDD). The prevalence of severe SMA among students was found to be 14.21%. Additionally, the findings demonstrated a significant correlation between increased dependence on social media and a higher incidence of PMS, with this upward trend achieving statistical significance (Chi-square for trend = 10.13, p-value = 0.001). Furthermore, multivariate logistic regression analysis revealed that, after controlling for potential confounding variables, the adjusted odds ratio (AOR) for PMS in students with severe SMA was 5.35 times greater than that of students with mild SMA (p = 0.001).</p><p><strong>Conclusions: </strong>As the severity of SMA increases, the prevalence of PMS also rises. Given that PMS can significantly impact the quality of life and the educational and occupational performance of students, it is imperative to educate them on the appropriate use of social media. This education should focus on fostering effective management strategies, which can mitigate the adverse consequences associated with SMA.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"627"},"PeriodicalIF":3.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144538330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety planning and transdiagnostic cognitive behavioral therapy for adolescent suicide prevention in Mozambique: study protocol for the SPI/TCBT-S hybrid effectiveness/implementation cluster randomized trial.","authors":"Bradley H Wagenaar, Alberto Muanido, Morgan Turner, Kathryn L Lovero, Doyanne Darnell, Monisha Sharma, Katherine Anne Comtois, Isaías Ramiro, Vasco F J Cumbe","doi":"10.1186/s12888-025-07102-w","DOIUrl":"https://doi.org/10.1186/s12888-025-07102-w","url":null,"abstract":"<p><strong>Background: </strong>More than 75% of suicide deaths occur in low-and middle-income countries (LMICs) and almost 90% of adolescents who die by suicide live in LMICs. Globally, suicide is the fourth leading cause of death for youth aged 15-29. Six of the top 10 countries by suicide rates in the world are in the African region. Despite this, there are few to no evidence-based youth suicide prevention packages developed for, and tested in, the African context. To address this gap, this study aims to test effectiveness and implementation outcomes for the brief Safety Planning Intervention (SPI) and the more resource-intensive multi-session Transdiagnostic Cognitive Behavioral Therapy Intervention for Suicide Prevention (TCBT-S) delivered by non-specialists in Mozambican secondary schools.</p><p><strong>Methods: </strong>Using a three-arm, parallel, Hybrid Type-1 cluster randomized trial design, we will randomize 7 secondary schools each to Enhanced Usual Care (EUC), SPI alone, and TBCT-S (21 schools total) to evaluate effects on suicidal behaviors (primary) and suicidal ideation/depressive symptoms (secondary). Exploratory structural equation modeling will examine potential mechanisms of intervention effects. Implementation outcomes, barriers, and facilitators to EUC, SPI, and TCBT-S implementation will be assessed using the RE-AIM evaluation and CFIR determinant frameworks. Costs and cost-effectiveness will be evaluated using a Markov model parameterized with cost and trial outcomes data and be applied to projecting budget impact and potential scale-up to provincial and national levels.</p><p><strong>Discussion: </strong>This study is innovative in being the first, to our knowledge, to rigorously test SPI and TCBT-S for adolescent suicide prevention in Sub-Saharan Africa. By simultaneously testing the brief SPI alone - as well as integrated into a more resource-intensive TCBT-S - this study will examine whether the potential gains in effectiveness with the more resource intensive TCBT-S justify its scale-up versus the brief SPI intervention. If effective, SPI or TCBT-S have a large potential to be rapidly scaled up to safeguard youth mental health in Mozambique and other similar LMICs.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov; NCT06465381; https://clinicaltrials.gov/study/NCT06465381 .</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"656"},"PeriodicalIF":3.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144538334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Suicidality among inpatients who absconded from a tertiary mental health facility in Uganda: a retrospective study.","authors":"Moses Muwanguzi, Mark Mohan Kaggwa","doi":"10.1186/s12888-025-07122-6","DOIUrl":"https://doi.org/10.1186/s12888-025-07122-6","url":null,"abstract":"<p><strong>Background: </strong>Suicidality and absconding from psychiatric care are two critical phenomena that complicate mental health care in developing countries. The aim of this study was twofold. First, to determine the prevalence of suicidality among absconders over two decades. Secondly, we set out to determine overall factors that influence the likelihood of having suicidal behaviors among absconders, as well as factors specific to each diagnosis.</p><p><strong>Methods: </strong>This was a retrospective chart review of files of patients who absconded from inpatient psychiatric care at a tertiary psychiatric facility in southwestern Uganda between 2000 and 2020. A pre-tested electronic questionnaire was used for data abstraction of sociodemographic characteristics, documented suicidality, and other clinical variables. Data cleaning and analysis were conducted using STATA V.17. Logistic regression was performed for factors associated with suicidality.</p><p><strong>Results: </strong>Among the absconders, 9.5% exhibited suicidality. Factors that heightened the odds of suicidality among absconders included being divorced or separated (adjusted odds ratio [aOR] = 2.00, 95% Confidence Interval [CI]: 1.20-3.31, p = 0.007), having depression (aOR = 5.41, 95% CI: 2.47-11.82, p < 0.001), a history of substance use (aOR = 1.50, 95% CI: 1.01-2.23, p = 0.049), and experiencing violence before hospitalization (aOR = 1.83, 95% CI: 1.14-2.94, p = 0.013). In contrast, substance use disorder (aOR = 0.25, 95% CI: 0.10-0.62, p = 0.003) and having schizophrenic spectrum disorders (aOR = 0.35, 95% CI: 0.18-0.68, p = 0.002) were linked to a decreased likelihood of suicidality among those who absconded.</p><p><strong>Conclusion: </strong>This study reveals a high burden of suicidality among individuals who abscond, with important risk factors such as marital status, depression, and a history of experiencing violence. It was noted that substance use disorder and schizophrenia spectrum disorders are associated with a reduced suicide risk. This study shows a significant interplay between clinical and demographic factors in predicting suicidality.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"628"},"PeriodicalIF":3.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144538338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mental health treatment and its impact on survival outcomes in patients with comorbid mental health and cardiovascular diseases: a retrospective cohort study.","authors":"Tirsit Ketsela Zeleke, Fasil Bayafers Tamene, Gebremariam Wulie Geremew, Tekletsadik Tekleslassie Alemayehu, Minichil Chanie Worku, Samuel Agegnew Wondm, Aschalew Mulatu Tefera, Ayelign Eshete Fitgu, Wubetu Yihunie Belay, Abraham Teym, Rahel Belete Abebe, Bantayehu Addis Tegegne","doi":"10.1186/s12888-025-07035-4","DOIUrl":"https://doi.org/10.1186/s12888-025-07035-4","url":null,"abstract":"","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"609"},"PeriodicalIF":3.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144538342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The burden of mental, and substance use disorders in Saudi Arabia: results from the global burden of disease study 2019.","authors":"Majed Ramadan, Khulud K Alharbi","doi":"10.1186/s12888-025-07041-6","DOIUrl":"https://doi.org/10.1186/s12888-025-07041-6","url":null,"abstract":"<p><strong>Background: </strong>Mental and substance use disorders represent a significant public health challenge worldwide. In Saudi Arabia also a high burden of disease associated with mental disorders accounted for about 7.3% of the total burden of disease in the country. This study aimed to assess the temporal trends of prevalence, incidence, years-lived with disability (YLDs), and disability-adjusted life-years (DALYs) rates due to mental and substance use disorders over a 30-year period in Saudi Arabia.</p><p><strong>Method: </strong>The data was obtained from The Global Burden of Disease (GBD) 2019. The GBD provided inclusive and accessible epidemiological data on 369 diseases and injuries, as well as 87 risk factors, from 1990 to 2019.</p><p><strong>Results: </strong>In 2019, there were 5,032,669 (95%) uncertainty intervals (UI) 3·5-9·9)) adults in Saudi Arabia with mental disorder, and 166,989 with substance use disorder. The largest proportion of prevalence increase from 1990 to 2019 was in eating disorder with 9.8% (95% UI 7.03-12.6). The most significant proportion of prevalence and incidence increase from 1990 to 2019 was in opioid disorders with 41.08% change in prevalence and 36.83 in incidence. From 1990 to 2019 there was + 26.46% increase in the annual change rate of age standardized DALYs due to substance use disorders.</p><p><strong>Conclusion: </strong>Mental disorders have a significant negative impact on large proportion of Saudis. While substance use disorder had moderate prevalence, it has been increasing rapidly since 2016. It is crucial for health officials and policymakers to make substantial investments in mental health and substance use services to promote prevention when possible and to offer accessible treatment, care, and rehabilitation. Efforts should also focus on integrating mental and physical health services.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"618"},"PeriodicalIF":3.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144538350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding anhedonia in major depressive disorder in Japan: epidemiology and unmet needs from patients' and physicians' perspectives.","authors":"Mami Kasahara-Kiritani, Tadafumi Kato, Akihide Wakamatsu, Thomas Webb, Keira Herr, Lawrence Vandervoort, Nan Li","doi":"10.1186/s12888-025-07089-4","DOIUrl":"https://doi.org/10.1186/s12888-025-07089-4","url":null,"abstract":"<p><strong>Background: </strong>Anhedonia (ANH), one of the core symptoms of major depressive disorder (MDD), poses a significant health challenge. We evaluated the prevalence of ANH among MDD patients in Japan, and elucidated patient journey from patients' and physicians' perspective.</p><p><strong>Methods: </strong>This cross-sectional observational study (April-May 2023) utilized a self-reported, online-based survey targeting the general population (non-physicians) and physicians. The general population (aged ≥ 18 years) were screened for MDD using Patient Health Questionnaire-9 (PHQ-9 ≥ 10); MDD patients were further screened for ANH using Snaith-Hamilton Pleasure Scale (SHAPS; MDD-ANH: SHAPS > 2, MDD non-ANH: SHAPS ≤ 2). The age- and gender-weighted prevalences of MDD and MDD-ANH, patient journey, and treatment goals and satisfaction between patients and physicians were reported. P-value < 0.05 was considered statistically significant.</p><p><strong>Results: </strong>The prevalence of MDD was 3.4% (n = 514; N = 15,266) and the prevalence of ANH in MDD was 66.9% (n = 344). Mean (± standard deviation) age of MDD-ANH patients (n = 282) was 46.1 ± 12.5 years, while for MDD non-ANH patients (n = 50) was 49.6 ± 8.5 years. Physicians (n = 60) had mean 21.9 years of experience working as psychiatrists. Physicians reported that 33.9% of their MDD patients had anhedonia. MDD-ANH patients scored significantly higher (p < 0.05) than MDD non-ANH patients on all PHQ-9 items, except for feeling tired/having little energy and poor appetite/overeating. A higher percentage of MDD-ANH patients reported current prescription use for depression than MDD non-ANH patients (67.0% vs. 51.3%; p = 0.0677). Treatment duration with multiple prescriptions was significantly longer in MDD-ANH than MDD non-ANH patients (102.1 ± 89.8 vs. 53.8 ± 33.7 months; p = 0.0035). The majority of physicians (90.0%) reported that they do not focus on treating anhedonia separately from MDD. Patients with MDD-ANH perceived \"reduce psychological anxiety\", \"control depressed mood\", and \"improve sleep quality\" as more important treatment goals, compared to physicians' importance to avoid suicidal thoughts, restore normal social function, and regain interest in hobbies. Treatment satisfaction levels were higher among physicians than MDD-ANH patients across all treatment goals.</p><p><strong>Conclusion: </strong>This study in Japan reported high prevalence of ANH among MDD patients which was significantly underestimated by physicians. Discordances in treatment goals and satisfaction were observed between physicians and MDD patients, highlighting the need for aligning patient and physician expectations.</p><p><strong>Trial registration: </strong>Not applicable.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"631"},"PeriodicalIF":3.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144538360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of insomnia with suicide attempts in Chinese chronic schizophrenia patients with and without autistic symptoms.","authors":"Wenzheng Li, Yu Liu, Rui Tao, Long Chen, Yang Liu, Daming Mo, Huanzhong Liu, Xiangyang Zhang","doi":"10.1186/s12888-025-07031-8","DOIUrl":"https://doi.org/10.1186/s12888-025-07031-8","url":null,"abstract":"<p><strong>Background: </strong>Numerous studies have shown that people with schizophrenia (SCZ) have a higher risk of suicide, and insomnia symptoms are common in SCZ patients. Autism symptoms (AS) are common in SCZ patients, and they are strongly linked to suicide. This study explored the connection between insomnia, autistic symptoms, and suicide attempts in Chinese patients with SCZ, it has not yet been investigated.</p><p><strong>Methods: </strong>955 Chinese chronic SCZ patients provided demographic and clinical information for data collection. Insomnia Symptom Severity Index (ISI) was used to assess the severity of insomnia symptoms, and Beck Scale for Suicide Ideation (BSS) was used to assess the risk of suicide. PANSS Autism Severity Score (PAUSS) was used to assess autistic symptoms.</p><p><strong>Results: </strong>The incidence of insomnia was higher in AS-SCZ patients than in non-AS-SCZ patients, but the incidence of suicide attempts was lower than that in non-AS-SCZ patients (all p < 0.05). In SCZ patients, insomnia severity scores were strongly associated with suicide attempts. Further correlational analysis showed that this association was only present in non-AS-SCZ patients (p < 0.05).</p><p><strong>Conclusions: </strong>Insomnia in patients with chronic SCZ may be influenced by autistic symptoms, potentially impacting the association between suicide attempts and insomnia.</p><p><strong>Trial registration: </strong>The study was a cross-sectional study, so there was no clinical trial registration.</p><p><strong>Clinical trial number: </strong>not applicable.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"604"},"PeriodicalIF":3.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144538271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}