BMC PsychiatryPub Date : 2025-03-27DOI: 10.1186/s12888-025-06733-3
Per-Erik Klasa, Mikael Sandell, Soo Aleman, Martin Kåberg
{"title":"Psychiatrist-led hepatitis C (HCV) treatment at an opioid agonist treatment clinic in Stockholm- a model to enhance the HCV continuum of care.","authors":"Per-Erik Klasa, Mikael Sandell, Soo Aleman, Martin Kåberg","doi":"10.1186/s12888-025-06733-3","DOIUrl":"10.1186/s12888-025-06733-3","url":null,"abstract":"<p><strong>Background: </strong>People with opioid agonist therapy (OAT) represent a population with an increased hepatitis C (HCV) prevalence. Recent studies provide strong evidence regarding effective HCV treatment outcomes and low levels of reinfection in this population. Increased access to HCV care for people with OAT is essential to reach the WHO goal of eliminating HCV as a major public health threat by 2030.</p><p><strong>Methods: </strong>The Maria OAT clinic, located in central Stockholm, provides OAT for approximately 500 patients. The majority have a history of injection drug use. In October 2017, psychiatrist-led HCV treatment was initiated, with remote consultation support from the local infectious diseases clinic. All OAT staff participated in HCV-specific education to increase HCV awareness. To evaluate HCV treatment outcomes for this model of care, we examined sustained virological response (SVR) and reinfection rates between January 2018 and December 2022.</p><p><strong>Results: </strong>Between October 2017 and June 2022, 133 participants received HCV treatment through weekly administrations or directly observed treatment. 72% were men, and the overall mean age was 44.7 years. Six participants were retreated, giving a total of 139 treatment initiations. All were HCV RNA negative at end of treatment, and 88% reached SVR. A total of 11 reinfections post SVR were noted, with a reinfection rate of 7.3/100 person-years (95% CI 4.1-12.9).</p><p><strong>Conclusion: </strong>Overall, successful HCV treatment results and levels of reinfections consistent with the literature were achieved. Bringing HCV diagnostics and treatment to an OAT clinic constitutes a good example of enhancing the HCV continuum of care. Furthermore, HCV treatment education for psychiatrists, addiction specialists and staff at OAT clinics makes HCV care more sustainable, as specifically noted during the COVID-19 pandemic. This successful model of care, introducing HCV treatment by psychiatrists on-site at OAT clinics, has now been further implemented at other OAT clinics in Stockholm.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"291"},"PeriodicalIF":3.4,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11948708/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143728388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sex differences in help-seeking behavior for depression in Lesotho: findings from a national survey.","authors":"Joshua Okyere, Castro Ayebeng, Kwamena Sekyi Dickson","doi":"10.1186/s12888-025-06749-9","DOIUrl":"10.1186/s12888-025-06749-9","url":null,"abstract":"<p><strong>Background: </strong>Given the many adverse health outcomes associated with depression, it is imperative to promote help-seeking behaviors. However, in Lesotho, there are no published studies that have investigated the help-seeking dynamics for depression. As such, the following questions remain unanswered: (a) What proportion of people living with depression in Lesotho seek help? (b) Are there significant sex differences in the factors associated with help-seeking for depression? To address these questions, we examined the prevalence and sex differences in the factors associated with help-seeking for depression in Lesotho.</p><p><strong>Methods: </strong>Secondary data from the 2023-2024 Lesotho demographic and health survey was used. We sampled 2172 men and 1484 women. Binary logistic regression models were fitted in STATA 18. Statistical significance was set at p < 0.05.</p><p><strong>Results: </strong>Overall, the proportion of women who sought help for depression was slightly higher (17.1% [14.4-20.3]) compared to men (16.4% [14.3-18.8]). More women (43.6%) sought help for depression from formal help providers than men. Likewise, more than half of male participants (60%) sought help from informal sources. Among men, those with moderate depression had significantly higher odds of seeking help (AOR = 2.02, 95%CI: 1.56-2.61). Help-seeking was also more likely among men with secondary education (AOR = 1.98, 95%CI: 1.13-3.47), those currently in a union (AOR = 1.85, 95%CI: 1.41-2.42) or previously in a union (AOR = 2.30, 95%CI: 1.54-3.45), and those in the richest wealth index (AOR = 1.64, 95%CI: 1.06-2.53). Among women, moderate (AOR = 2.41, 95%CI: 1.76-3.32) and severe depression (AOR = 3.42, 95%CI: 2.26-5.18) significantly increased help-seeking likelihood. Women aged 45-59 years (AOR = 2.46, 95%CI: 1.36-4.45), exposed to media (AOR = 1.63, 95%CI: 1.21-2.19), or consuming alcohol (AOR = 1.36, 95%CI: 1.01-1.84) also had higher odds of seeking help.</p><p><strong>Conclusion: </strong>Help-seeking for depression is low among men and women in Lesotho. However, the factors associated with help-seeking differ by sex. Among women, leveraging the media could yield more effective outcomes; among men, addressing poverty and improving education could prove effective in improving help-seeking for depression. The study also underscores a need to focus on harnessing the potential of informal support networks.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"290"},"PeriodicalIF":3.4,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11948660/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143728389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC PsychiatryPub Date : 2025-03-27DOI: 10.1186/s12888-025-06715-5
Yuting Zhan, Weixing Jing
{"title":"The impact of paternity-maternity matching on suicide risk among college students: a response surface analysis.","authors":"Yuting Zhan, Weixing Jing","doi":"10.1186/s12888-025-06715-5","DOIUrl":"10.1186/s12888-025-06715-5","url":null,"abstract":"<p><strong>Purpose: </strong>The objective of this study is to investigate the impact of father-child and mother-child relationships on the suicide risk of college students.</p><p><strong>Methods: </strong>A questionnaire survey was conducted on 1,215 college students using the Parent-Child Relationship Questionnaire and the Suicidal Behavior Questionnaire. 1,215 questionnaires were distributed, and after quality control, 948 were valid the Psychological Distress Questionnaire, Polynomial regression and response surface analyses were performed to analyze the data.</p><p><strong>Results: </strong>The study found a significant relationship between parent-child relationship patterns and suicide risk in college students. Students with high-quality relationships with both parents (\"high paternity-high maternity\") showed the lowest suicide risk. Conversely, those with poor relationships with both parents (\"low paternity-low maternity\") exhibited the highest risk. When examining discordant relationships, students with high father-child but low mother-child relationship quality showed lower suicide risk compared to those with low father-child but high mother-child relationship quality, suggesting a potentially stronger protective effect of father-child relationships in this cultural context. The study also found that psychological distress played a partial mediating role in the relationship between father-child relationship and college students' suicide risk, and a full mediating role in the relationship between mother-child relationship and college students' suicide risk.</p><p><strong>Conclusion: </strong>The conclusion drawn was that similar levels of father-child and mother-child relationships significantly predicted the risk of suicide among college students.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"296"},"PeriodicalIF":3.4,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11951733/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143728391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC PsychiatryPub Date : 2025-03-27DOI: 10.1186/s12888-025-06704-8
Ernest Owusu, Wanying Mao, Reham Shalaby, Hossam Eldin Elgendy, Belinda Agyapong, Ejemai Eboreime, Mobolaji A Lawal, Nnamdi Nkire, Yifeng Wei, Peter H Silverstone, Pierre Chue, Xin-Min Li, Wesley Vuong, Arto Ohinmaa, Valerie Taylor, Carla T Hilario, Andrew J Greenshaw, Vincent I O Agyapong
{"title":"The prevalence and correlates of low resilience in patients prior to discharge from acute psychiatric units in Alberta, Canada.","authors":"Ernest Owusu, Wanying Mao, Reham Shalaby, Hossam Eldin Elgendy, Belinda Agyapong, Ejemai Eboreime, Mobolaji A Lawal, Nnamdi Nkire, Yifeng Wei, Peter H Silverstone, Pierre Chue, Xin-Min Li, Wesley Vuong, Arto Ohinmaa, Valerie Taylor, Carla T Hilario, Andrew J Greenshaw, Vincent I O Agyapong","doi":"10.1186/s12888-025-06704-8","DOIUrl":"10.1186/s12888-025-06704-8","url":null,"abstract":"<p><strong>Background: </strong>Many people experience at least one traumatic event in their lifetime. Although such traumatic events can precipitate psychiatric disorders, many individuals exhibit high resilience by adapting to such events with little disruption or may recover their baseline level of functioning after a transient symptomatic period. Low levels of resilience are under-explored, and this study investigates the prevalence and correlates of low resilience in patients before discharge from psychiatric acute care facilities.</p><p><strong>Methods: </strong>Respondents for this study were recruited from nine psychiatric in-patient units across Alberta. Demographic and clinical information were collected via a REDCap online survey. The brief resilience scale (BRS) was used to measure levels of resilience where a score of less than 3.0 was indicative of low resilience. A chi-square analysis followed by a binary logistic regression model was employed to identify significant predictors of low resilience.</p><p><strong>Results: </strong>A total of 1,004 individuals took part in this study. Of these 35.9% were less than 25 years old, 34.7% were above 40 years old, 54.8% were female, and 62.3% self-identified as Caucasian. The prevalence of low resilience in the study cohort was 55.3%. Respondents who identified as females were one and a half times more likely to show low resilience (OR = 1.564; 95% C.I. = 1.79-2.10), while individuals with 'other gender' identity were three and a half times more likely to evidence low resilience (OR = 3.646; 95% C.I. = 1.36-9.71) compared to males. Similarly, Caucasians were two and one-and-a-half times respectively more likely to present with low resilience compared with respondents who identified as Black (OR = 2.21; 95% C.I. = 1.45-3.70) or Asian (OR = 1.589; 95% C.I. = 1.45-2.44). Additionally, individuals with a diagnosis of depression were significantly more likely to have low resilience than those with a diagnosis of either bipolar disorder (OR = 2.567; 95% C.I. = 1.72-3.85) or schizophrenia (OR = 4.081;95% C.I. = 2.63-6.25).</p><p><strong>Conclusion: </strong>Several demographic and clinical factors were identified as predictors of likely low resilience. The findings may facilitate the identification of vulnerable groups to enable their increased access to support programs that may enhance resilience.</p><p><strong>Clinical trial registration: </strong>clinicaltrials.gov, NCT05133726. Registered on the 24th of November 2021.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"295"},"PeriodicalIF":3.4,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11951555/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143728392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC PsychiatryPub Date : 2025-03-27DOI: 10.1186/s12888-025-06729-z
Hayley Denyer, Ewan Carr, Qigang Deng, Philip Asherson, Andrea Bilbow, Amos Folarin, Madeleine J Groom, Chris Hollis, Heet Sankesara, Richard Jb Dobson, Jonna Kuntsi
{"title":"A 10-week remote monitoring study of sleep features and their variability in individuals with and without ADHD.","authors":"Hayley Denyer, Ewan Carr, Qigang Deng, Philip Asherson, Andrea Bilbow, Amos Folarin, Madeleine J Groom, Chris Hollis, Heet Sankesara, Richard Jb Dobson, Jonna Kuntsi","doi":"10.1186/s12888-025-06729-z","DOIUrl":"10.1186/s12888-025-06729-z","url":null,"abstract":"<p><strong>Background: </strong>People with attention deficit hyperactivity disorder (ADHD) often report disturbed sleep, as well as co-occurring symptoms of anxiety and depression. Yet studies employing objective assessments often do not show as many sleep disturbances compared to subjective measures. These discrepancies may relate to subjective reports capturing problematic nights, which may not be captured in a single night's sleep or by averaging objective measurements over several nights. Given that variability in behaviours is in general strongly linked to ADHD, individuals with ADHD could have greater sleep variability than individuals without ADHD. Using active and passive remote monitoring, we investigate differences in the level and variability of daily sleep behaviours between individuals with and without ADHD and explore if sleep is associated with changes in anxiety and depressive symptoms across a 10-week remote monitoring period.</p><p><strong>Methods: </strong>Forty individuals (20 with ADHD, 20 without) took part in a 10-week remote monitoring study. Active monitoring involved participants completing questionnaires on ADHD and co-occurring psychiatric symptoms at weeks 2, 6 and 10. Passive monitoring involved participants wearing a wearable device (Fitbit) that measured sleep each night.</p><p><strong>Results: </strong>Individuals with and without ADHD were similar in the levels of sleep recorded each night. However, compared to those without ADHD, participants with ADHD had more variable sleep duration, sleep onset and offset, and sleep efficiency over 10 weeks. Within-individual associations of co-occurring anxiety and depressive symptoms with the sleep features were non-significant.</p><p><strong>Conclusions: </strong>In a 10-week remote monitoring study of sleep using a wearable device, we show that what distinguishes individuals with ADHD from those without is their greater variability in sleep features: participants with ADHD had a more variable sleep duration, sleep onset and offset, and sleep efficiency. Inconsistency and high variability are hallmarks of ADHD, and we show that this characteristic extends also to sleep among adolescents and adults with ADHD.</p><p><strong>Trial registration: </strong>Clinical trial number: not applicable.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"294"},"PeriodicalIF":3.4,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11951673/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143728385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC PsychiatryPub Date : 2025-03-27DOI: 10.1186/s12888-025-06699-2
Xiaoqian Luan, Zhou Jin, Shenhang Xia, Jin Li, Yao An, Jiaqi Gao, Shengya Wang, Huwei Xia, Sipei Pan, Yao Zhang, Weihong Song, Yili Wu
{"title":"Smoking impairs cognitive function through the mediating effect of periodontitis in older adults.","authors":"Xiaoqian Luan, Zhou Jin, Shenhang Xia, Jin Li, Yao An, Jiaqi Gao, Shengya Wang, Huwei Xia, Sipei Pan, Yao Zhang, Weihong Song, Yili Wu","doi":"10.1186/s12888-025-06699-2","DOIUrl":"10.1186/s12888-025-06699-2","url":null,"abstract":"<p><strong>Objectives: </strong>Evidence has shown that both smoking and periodontitis were linked to cognitive impairment. This study examines whether periodontitis mediates the effects of smoking status on cognitive function in older adults.</p><p><strong>Methods: </strong>Using data from the National Health and Nutrition Examination Survey (NHANES) 2011-2014, the study included 1728 older participants who have data on smoking, serum cotinine, periodontal examination, and cognitive function. Mediation analysis was performed to test whether extent of periodontitis mediated associations between smoking status and cognitive function, adjusted for sociodemographic and basic health factors.</p><p><strong>Results: </strong>Compared to never-smokers, daily smokers exhibited significantly worse global cognitive function, with periodontitis mediating this effect (effect= -0.16; 95% CI= -0.29, -0.05). Similarly, periodontitis mediated the association between serum cotinine levels and cognitive function in the total sample (effect= -0.02; 95% CI= -0.03, -0.00).</p><p><strong>Conclusions: </strong>Periodontitis significantly mediates the impact of smoking on cognitive function. The findings highlight the potential roles of maintaining oral health and smoking cessation in mitigating cognitive decline.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"292"},"PeriodicalIF":3.4,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11948936/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143728390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC PsychiatryPub Date : 2025-03-26DOI: 10.1186/s12888-025-06538-4
Xuequan Zhu, Xiongying Chen, Yuanzhen Wu, Lei Feng, Xu Chen
{"title":"Longitudinal trajectories of subjective cognitive complaints in patients with major depressive disorder and similar objective cognitive trajectories.","authors":"Xuequan Zhu, Xiongying Chen, Yuanzhen Wu, Lei Feng, Xu Chen","doi":"10.1186/s12888-025-06538-4","DOIUrl":"10.1186/s12888-025-06538-4","url":null,"abstract":"<p><strong>Background: </strong>We examined the factors influencing various subtypes of subjective cognitive change in patients who shared similar objective cognitive trajectories within 6 months.</p><p><strong>Method: </strong>We used data from an observational, prospective, cohort study, including 598 patients with major depressive disorder (MDD) in latent class mixed models based on the digit symbol substitution test performance. Participants were stratified into four distinct objective cognitive layers: \"low cognitive performance,\" \"lower-middle cognitive performance,\" \"upper-middle cognitive performance,\" and \"high cognitive performance.\" Within each of the four layers, the trajectories of subjective cognitive complaints were identified. Multinomial regression was employed, with cognitive complaint trajectories as the outcome, and depressive symptoms, clinical features, and other covariates as predictors.</p><p><strong>Results: </strong>The factors influencing the subjective trajectories varied among the different objective layers. Patients with comorbid anxiety disorders or functional syndromes had more prominent self-reported cognitive symptoms and a slower rate of improvement. Younger age and lower education level were also influential factors for delayed remission of subjective cognitive function. Disease severity and antidepressant type did not contribute to dedifferentiating subjective cognitive trajectory subtypes within different subjective cognitive trajectories.</p><p><strong>Conclusion: </strong>Despite similar objective cognitive trajectories, subjective perceptions of these cognitive changes are heterogeneous. These findings deepen our understanding of the multifaceted nature of cognitive change in individuals with MDD and underscore the importance of considering a range of factors when interpreting and treating cognitive impairment at an early stage.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"287"},"PeriodicalIF":3.4,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938668/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Machine learning-driven development of a stratified CES-D screening system: optimizing depression assessment through adaptive item selection.","authors":"Ruo-Fei Xu, Zhen-Jing Liu, Shunan Ouyang, Qin Dong, Wen-Jing Yan, Dong-Wu Xu","doi":"10.1186/s12888-025-06693-8","DOIUrl":"10.1186/s12888-025-06693-8","url":null,"abstract":"<p><strong>Objective: </strong>To develop a stratified screening tool through machine learning approaches for the Center for Epidemiologic Studies Depression Scale (CES-D-20) while maintaining diagnostic accuracy, addressing the efficiency limitations in large-scale applications.</p><p><strong>Methods: </strong>Data were derived from the Chinese Psychological Health Guard Project (primary sample: n = 179,877; age 9-18) and China Labor-force Dynamics Survey (validation samples across age spans). We employed a two-stage machine learning approach: first applying Recursive Feature Elimination with multiple linear regression to identify core predictive items for total depression scores, followed by logistic regression for optimizing depression classification (CES-D ≥ 16). Model performance was systematically evaluated through discrimination (ROC analysis), calibration (Brier score), and clinical utility analyses (decision curve analysis), with additional validation using random forest and support vector machine algorithms across independent samples.</p><p><strong>Results: </strong>The resulting stratified screening system consists of an initial four-item rapid screening layer (encompassing emotional, cognitive, and interpersonal dimensions) for detecting probable depression (AUC = 0.982, sensitivity = 0.945, specificity = 0.926), followed by an enhanced assessment layer with five additional items. Together, these nine items enable accurate prediction of the full CES-D-20 total score (R<sup>2</sup> = 0.957). This stratified approach demonstrated robust generalizability across age groups (R<sup>2</sup> > 0.94, accuracy > 0.91) and time points. Calibration analyses and decision curve analyses confirmed optimal clinical utility, particularly in the critical risk threshold range (0.3-0.6).</p><p><strong>Conclusions: </strong>This study contributes to the refinement of CES-D by developing a machine learning-derived stratified screening version, offering an efficient and reliable approach that optimizes assessment burden while maintaining excellent psychometric properties. The stratified design makes it particularly valuable for large-scale mental health screening programs, enabling efficient risk stratification and targeted assessment allocation.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"286"},"PeriodicalIF":3.4,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938587/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Schema therapy in partially sighted individuals with a focus on social isolation and self-esteem: an interventional study.","authors":"Amirhossein Abbasi, Jamileh Farokhzadian, Mahya Torkaman, Sakineh Miri","doi":"10.1186/s12888-025-06732-4","DOIUrl":"10.1186/s12888-025-06732-4","url":null,"abstract":"<p><strong>Background: </strong>Visual impairment can lead to low self-esteem and social isolation for partially sighted individuals. Schema therapy offers a systematic approach to identifying and modifying maladaptive schemas formed in the past. This therapy has proven effective in treating mental disorders and preventing their recurrence. This study aimed to investigate the effectiveness of schema therapy in addressing social isolation and enhancing self-esteem among partially sighted individuals.</p><p><strong>Methods: </strong>This interventional study involved 66 partially sighted individuals who referred to Tavangaran Institute in Shiraz, southwestern Iran. Participants were randomly assigned to two groups: an intervention group (n = 33) and a control group (n = 33). The intervention group received eight sessions of schema therapy over four weeks, with two sessions per week. Data were collected from both groups using the University of California at Los Angeles Loneliness Scale and the Rosenberg Self-Esteem Scale at three time points: before the intervention, immediately after the intervention, and one month post-intervention.</p><p><strong>Results: </strong>Mean social isolation scores in the intervention group decreased significantly from 65.03 ± 2.76 before the intervention to 35.93 ± 2.80 immediately after the intervention, and 38.36 ± 3.19 one month later (p < 0.001). Additionally, mean self-esteem scores increased significantly from 13.27 ± 1.27 to 22.30 ± 2.24 immediately after the intervention and 20.75 ± 2.43 one month after the intervention (p < 0.001). These post-intervention scores were significantly higher than that in the control group (p-value < 0.001).</p><p><strong>Conclusion: </strong>The results of this study demonstrated the effectiveness of schema therapy in improving self-esteem and reducing social isolation among partially sighted individuals. Healthcare providers, including psychologists and psychiatric nurses, are encouraged to consider using this intervention with other vulnerable groups, such as individuals with disabilities or physical impairments, who may experience similar challenges in self-esteem and social interaction.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"289"},"PeriodicalIF":3.4,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938656/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}