BMC Psychiatry最新文献

{"title":"Serum NR1 and NR2 concentrations in first-episode schizophrenia and clinical high-risk for psychosis.","authors":"Zhen Mao, Feng Li, Lige Ge, Wenpeng Hou, Yushen Ding, Feifei Wang, Yujie Wen, Xueqi Wang, Yongying Cheng, Weiwei Hou, Lu Wang, Xinke Shi, Qijing Bo, Fang Dong","doi":"10.1186/s12888-025-06950-w","DOIUrl":"10.1186/s12888-025-06950-w","url":null,"abstract":"<p><strong>Background: </strong>This study evaluated the utility of serum NR1 and NR2 concentrations in identifying individuals with first-episode schizophrenia (FES) and clinical high risk (CHR) as well as their correlations with clinical symptoms and cognitive domains.</p><p><strong>Methods: </strong>This cross-sectional study compared peripheral blood NR1 and NR2 concentrations among the FES, CHR, and healthy control (HC) groups and examined their association with cognitive function. Serum concentrations of NR1 and NR2 subunits were measured using ELISA, and cognitive function was assessed using the MATRICS Consensus Cognitive Battery. Concentrations were compared among groups using the analysis of covariance or non-parametric tests and ROC curve analysis, and correlation was determined using the Pearson or Spearman method.</p><p><strong>Results: </strong>A total of 41 FES cases, 34 CHR cases, and 41 HC were included in the study. Serum NR1 concentrations significantly varied among the three groups (Z = 16.19, P < 0.001) and were significantly different between the FES group and the CHR (Z = -4.04, P < 0.001) and HC groups (Z = -2.49, P = 0.01). Additionally, serum NR2 concentration was significantly different between the CHR and HC groups (F = 5.37, P = 0.02). In the FES group, serum NR1 concentration was negatively correlated with speed of processing (r = -0.41, P = 0.02), whereas serum NR2 concentration was negatively correlated with verbal learning (r = -0.40, P = 0.02). In the CHR group, serum NR1 concentration was positively correlated with the total MCCB score (r = 0.40, P = 0.04). ROC curve analysis showed that NR2 level was better for discriminating FES (AUC: 69%; sensitivity: 56%; specificity: 85%; optimal cutoff value: 32.80 ng/mL) and CHR (AUC: 74%; sensitivity: 62%; specificity: 85%; optimal cutoff value: 32.77 ng/mL).</p><p><strong>Conclusions: </strong>Serum NR1 and NR2 concentrations show potential for early identification of individuals with psychosis, but further validation is needed, and they are also correlated with cognition. Furthermore, serum NR2 concentration is more stable and serves as a promising objective biomarker for quantitative assessment.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"493"},"PeriodicalIF":3.4,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12083129/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case of dementia with Lewy bodies with psychosis induced by low-dose gabapentinoids.","authors":"Hideki Kanemoto, Taisuke Akiyama, Daiki Taomoto, Manabu Ikeda","doi":"10.1186/s12888-025-06937-7","DOIUrl":"10.1186/s12888-025-06937-7","url":null,"abstract":"<p><strong>Background: </strong>Hypersensitivity to antipsychotic drugs is one of the supportive features of dementia with Lewy bodies, and side effects to drugs other than antipsychotics are also known to occur frequently. We experienced a case of dementia with Lewy bodies in which hallucinations and delusions repeatedly appeared and disappeared after administration and discontinuation of mirogabalin and pregabalin.</p><p><strong>Case presentation: </strong>The patient, a woman in her late 70s, developed hallucinations and delusional misidentification of places and persons immediately after receiving a prescription of mirogabalin (15 mg daily) for neuropathic pain. After discontinuation of mirogabalin, her hallucinatory delusions improved but remained. Mild dementia and mild parkinsonism were associated, cognitive fluctuations were evident, and dopamine-transporter scintigraphy showed bilateral striatal uptake reduction. Residual psychosis resolved with donepezil. Later, when the pain worsened, pregabalin (25 mg daily) was administered, and the psychosis recurred and resolved with discontinuation.</p><p><strong>Conclusions: </strong>Although pregabalin-induced psychosis has been reported at higher doses (300-450 mg daily), it has not been reported at doses as low as those used in this patient. Gabapentinoids may cause psychosis in patients with dementia with Lewy bodies even at low doses, likely due to hypersensitivity to gabapentinoids in DLB.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"491"},"PeriodicalIF":3.4,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12083094/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and internal validation of a depressive symptoms prediction model among the patients with cardiovascular disease who have recovered from SARS-CoV-2 infection in Wuhan, China: a cross-sectional study.","authors":"Zhenwei Dai, Xin Liu, Shu Jing, Hao Wang, Yiman Huang, Jiaqi Fu, Yijin Wu, Ling Zhang, Bicheng Han, Xiaoyou Su","doi":"10.1186/s12888-025-06886-1","DOIUrl":"10.1186/s12888-025-06886-1","url":null,"abstract":"<p><strong>Background: </strong>Middle-aged  and elderly patients with cardiovascular disease (CVD) who have recovered from SARS-CoV-2 infection may experience depressive symptoms due to the physical and psychological impact of the pandemic.</p><p><strong>Objective: </strong>To investigate the prevalence and predictors of depressive symptoms among the middle-aged and elderly with CVD who have recovered from SARS-CoV-2 infection in Wuhan, China, and to develop a prediction model for depressive symptoms.</p><p><strong>Methods: </strong>A cross-sectional study was conducted among 462 former SARS-CoV-2 middle-aged and elderly patients with CVD in Jianghan District, Wuhan, China from June 10 to July 25, 2021. Depressive symptoms were assessed by the Patient Health Questionnaire-9 (PHQ-9). Potential predictors of depressive symptoms were selected by the least absolute shrinkage and selection operator (LASSO) regression. A prediction model was developed by random forest (RF) and logistic regression models and compared by the area under the receiver operating characteristic curve (AUROC). The discrimination, calibration, and practical utility of the prediction model were evaluated by the receiver operating characteristic (ROC) curve, calibration curve, and decision curve analysis (DCA). Bootstrap sampling was used for internal validation.</p><p><strong>Results: </strong>The prevalence of depressive symptoms among the participants was 35.93%. The prediction model included age, stethalgia after recovery, insomnia after recovery, post-traumatic stress disorder (PTSD), anxiety, fatigue, and perceived social support as predictors. The AUROC of the logistic regression model was 0.909 (95%CI: 0.879 ~ 0.939), indicating good discrimination. The calibration curve showed good calibration. The DCA showed that the prediction model had a net benefit for a wide range of risk thresholds. The internal validation confirmed the stability of the prediction model.</p><p><strong>Conclusion: </strong>Depressive symptoms are common among middle-aged and elderly CVD patients who have recovered from SARS-CoV-2 infection in Wuhan, China. A prediction model with satisfactory performance was developed to estimate the risk of depressive symptoms among this population. Interventions targeting long COVID symptoms and social support should be considered to prevent depressive symptoms in CVD patients.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"492"},"PeriodicalIF":3.4,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12082991/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is adults' borderline personality disorder associated with their attachment experiences, rejection and mental security? A cross-sectional study.","authors":"Mojdeh Askari, Mohammad Ali Zakeri, Alaa Hamza Hermis, Xiao Xu, Sri Widowati, Reza Mohammadmehr","doi":"10.1186/s12888-025-06900-6","DOIUrl":"10.1186/s12888-025-06900-6","url":null,"abstract":"<p><strong>Background: </strong>Borderline personality disorder (BPD) is highly correlated with other mental disorders and poses significant psychological and social risks both to individuals and to society. This study aims to investigate the relationship between attachment, perceived rejection, and psychological security with BPD.</p><p><strong>Methods: </strong>This cross-sectional correlational study was conducted on 89 BPD patients. The BPD patients was selected using a convenience sampling method. The instruments used in this study included the demographic characteristics form, the Rejection Sensitivity Perception Scale (RSPS), the Revised Adult Attachment Scale (RAAS), the Maslow's Psychological Security scale and the Borderline Personality Inventory (BPI). Data were analyzed using SPSS version 22, employing Pearson correlation and regression analysis methods.</p><p><strong>Results: </strong>The mean scores of BPI were 25.59 ± 5.19. The mean scores for perceived rejection and attachment were 7.71 ± 3.52 and 35.76 ± 6.64, respectively. We found a positive significant correlation between perceived rejection (r = 0.35, p = 0.001), attachment (r = 0.25, p = 0.017) and psychological and social security (r = 0.55, p < 0.001) with BPI. The results of multivariate linear regression indicated that psychological and social security, perceived rejection, and gender predicted 40% of the variance in BPD (R² = 40%) (p < 0.05).</p><p><strong>Conclusions: </strong>In the present study, attachment, rejection, and sense of security were found to be associated with BPD. To prevent BPD, it is essential to consider factors such as attachment, rejection, and security. Therefore, mental health care providers are advised to plan and implement appropriate interventions to identify and improve these variables, thereby enhancing related health outcomes.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"490"},"PeriodicalIF":3.4,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12080062/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between renal function and cognitive impairment in patients with stable schizophrenia: a multicenter cross-sectional study.","authors":"Cong Cao, Xuehao Xu, Sumei Shen, Xiyan Bao, Fenglan Wang, Weishan Sun, Tao Gu, Lingling Hua, Chengbing Huang, Zhenlin Chen, Xuebin Qu, Aihua Zhou","doi":"10.1186/s12888-025-06952-8","DOIUrl":"10.1186/s12888-025-06952-8","url":null,"abstract":"<p><strong>Objective: </strong>Clinically stable inpatients with schizophrenia have generalized impairment of cognitive function along with abnormalities in renal function, but the link between cognitive function and renal function has been underexplored.</p><p><strong>Methods: </strong>This study enrolled 216 hospitalized patients with clinically stable schizophrenia. Demographic and renal function parameters were collected from electronic medical records. Cognitive function was assessed using the Chinese Brief Cognitive Test (C-BCT). To analyze the correlations between renal function and processing speed, attention, working memory, and executive function in patients hospitalized with clinically stable schizophrenia. Covariate-adjusted linear and multivariate logistic regression models were constructed to determine the relationship between renal function and cognitive function. ROC analysis was used to further investigate the prediction of renal function indices in assessing stable schizophrenia inpatients.</p><p><strong>Results: </strong>Significant variations in serum Cystatin C (CysC), β2-microglobulin (β2-MG), and uric acid (UA) levels were observed among hospitalized patients with clinically stable schizophrenia across different cognitive impairment severities. Correlation analysis revealed a significant association between serum CysC levels and C-BCT scores in hospitalized patients with stable schizophrenia (β = 0.174, 95%CI:0.265 ~ 1.720, p = 0.008). Particularly strong correlations were observed with processing speed T-scores (β = -0.200, 95%CI: -33.446 ~ -7.230, p = 0.03) and executive function T-scores (β = -0.171, 95%CI: -17.277 ~ -2.082, p = 0.013). Binary logistic regression analysis further confirmed that CysC may be a risk factor for exacerbation of cognitive impairment in stable schizophrenia (OR = 12.741, 95%CI: 1.424 ~ 114.005, p = 0.023). The combined serum CysC, β2-MG, and UA test for cognitive function in stable schizophrenia inpatients had an AUC area of 0.71, with a sensitivity and specificity of 79.5% and 60.5%, respectively, and a predictive value superior to that of an independent diagnosis.</p><p><strong>Conclusion: </strong>In hospitalized patients with stable schizophrenia, serum CysC levels are positively correlated with the severity of cognitive impairment, particularly showing significant associations with information processing speed and executive function. CysC may be a risk factor for exacerbating cognitive impairment in these patients. The combined diagnostic value of serum CysC, β2-MG, and UA demonstrated moderate accuracy in identifying stable schizophrenia cognitive impairment. These data support the potential of CysC as a biomarker of cognitive function in stable schizophrenia.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"494"},"PeriodicalIF":3.4,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12082902/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between living arrangement and psychological well-being among patients with major depressive disorder: the moderating role of body mass index.","authors":"Chengxi Wen, Yifeng Liu, Yanzhi Li, Ruiying Chen, Hao Zhao, Xiaojuan Zhang, Xiaoxin Zhuang, Yuhua Liao, Jiejing Hao, Yan Chen, Wanxin Wang, Huiming Zhang, Lan Guo, Roger S McIntyre, Kayla M Teopiz, Ciyong Lu, Xue Han","doi":"10.1186/s12888-025-06947-5","DOIUrl":"https://doi.org/10.1186/s12888-025-06947-5","url":null,"abstract":"<p><strong>Background: </strong>Major depressive disorder (MDD) is highly prevalent globally, significantly impacting psychological well-being (PWB). Herein, we aim to evaluate the impact of different living arrangements on PWB in individuals with MDD and explore the potential moderating role of BMI in this relationship.</p><p><strong>Methods: </strong>Participants with MDD were recruited from a specialist mental health hospital between December 2019 and April 2023. The diagnosis of MDD was assessed by trained psychiatrists using the Mini-International Neuropsychiatric Interview (M.I.N.I.). Psychological well-being was evaluated using the World Health Organization-Five Well-Being Index. Univariable and multivariable logistic regression models were used to examine the association between different living arrangements and PWB at the 12-month follow-up. The Participants were categorized into underweight, normal weight, and overweight groups based on BMI, followed by conducting stratified analysis.</p><p><strong>Results: </strong>After adjusting for covariates, living with family (AOR = 1.80, 95%CI = 1.14-2.87, P = 0.026) was associated with a higher PWB. There was significant moderating effect of BMI on the association of living arrangements with PWB (P = 0.049). The stratification analyses revealed significant associations between living arrangements and PWB in the normal weight group, while no significant associations were found in the underweight and overweight groups.</p><p><strong>Conclusions: </strong>Living with family was significantly associated with higher levels of PWB in individuals with MDD, especially among those with a normal BMI. These findings highlight the synergistic effect of living with family and maintaining a healthy BMI on improving PWB in depressed individuals.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"483"},"PeriodicalIF":3.4,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12076959/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring glucagon-like peptide-1 receptor agonists as potential disease-modifying agent in psychiatric and neurodevelopmental conditions: evidence from a drug target Mendelian randomization.","authors":"Lingfeng Zhang, Xiang Chen, Yantao Xu, Jiachen Liu, Zhongchun Liu","doi":"10.1186/s12888-025-06914-0","DOIUrl":"https://doi.org/10.1186/s12888-025-06914-0","url":null,"abstract":"<p><strong>Background: </strong>Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have recently received Food and Drug Administration (FDA) approval for obesity management. However, the causal relationship between GLP-1RAs and psychiatric and neurodevelopmental conditions remains unclear.</p><p><strong>Methods: </strong>We used Mendelian randomization (MR) to investigate the association between genetically proxied GLP-1RA exposure and 12 psychiatric and neurodevelopmental conditions. Genetic instruments were derived from cis-eQTLs for GLP-1R, and analyses were conducted using large-scale GWAS datasets. Type 2 diabetes was included as a positive control (107,133 cases, 656,672 controls). Findings were assessed across multiple independent datasets, including FinnGen, Psychiatric Genomics Consortium (PGC), and UK Biobank, and were synthesized through meta-analysis.</p><p><strong>Result: </strong>Genetically proxied GLP-1RA exposure was associated with a lower risk of schizophrenia (OR = 0.72, 95% CI [0.61-0.86]), bipolar disorder (OR = 0.91, 95% CI [0.88-0.94]), bulimia nervosa (OR = 0.34, 95% CI [0.23-0.52]), post-traumatic stress disorder (PTSD) (OR = 0.45, 95% CI [0.31-0.67]), and autism (OR = 0.55, 95% CI [0.32-0.93]), all P < 0.001. Conversely, higher GLP-1R expression was associated with an increased risk of obsessive-compulsive disorder (OCD) (OR = 2.30, 95% CI [1.26-4.22], P < 0.001). No significant associations were observed for anorexia nervosa, broad depression, major depressive disorder (MDD), or suicide and intentional self-harm. Sensitivity analyses and heterogeneity assessments supported the robustness of these findings across multiple cohorts.</p><p><strong>Limitations: </strong>GLP-1RAs reduced some psychiatric and neurodevelopmental conditions but lacked extensive evidence. Bulimia nervosa and PTSD evidence was limited to one database. Bipolar disorder and OCD results varied, with significant OCD findings in one database. The study's European ancestry focus limits generalizability. Rare disorders and disease progression were not examined. Future research needs diverse populations, long-term follow-ups, and treatment exploration.</p><p><strong>Conclusions: </strong>Our study suggests that GLP-1RAs may decrease the risk of schizophrenia, anxiety disorders, bipolar disorder, bulimia nervosa, PTSD, and autism, but may increase the risk of OCD. Larger randomized controlled trials with long-term follow-up are necessary to confirm these associations and evaluate the risk-benefit ratios.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"484"},"PeriodicalIF":3.4,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12079933/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Symptom network between problematic smartphone use and poor sleep quality in adolescents with depression.","authors":"Yongjie Zhou, Jian Gong, Jing Shao, Nan Yan, Linlin Meng, Kongliang He, Ying Shen, Qian Wei, Chunyan Zhang, Xuan Lei, Yuehua Cao, Yanni Wang","doi":"10.1186/s12888-025-06920-2","DOIUrl":"10.1186/s12888-025-06920-2","url":null,"abstract":"<p><strong>Background: </strong>This study established a network structure between problematic smartphone use (PSU) and poor sleep quality (PSQ) to explore their symptomatic relationship in adolescents with depression.</p><p><strong>Methods: </strong>The data were obtained from the baseline data of the Chinese Adolescent Depression Cohort, which included depressed adolescents aged between 12 and 18 years. PSU and PSQ were assessed via the Mobile Phone Addiction Index (MPAI) and Pittsburgh Sleep Quality Index (PSQI). This study utilized network analysis to identify the core and bridge symptoms between PSU and PSQ.</p><p><strong>Results: </strong>The core symptom of the network was 'Anxiety and craving' in the PSU. The symptoms 'Anxiety and craving', 'Daytime dysfunction' and 'Sleep disturbances' could function as bridges between PSU and PSQ. The symptom 'Anxiety and craving' played the most important role in the interaction between PSU and PSQ. It affects 'Sleep disturbances' that contribute to the harm of problematic smartphone use to sleep quality. The symptom 'Daytime dysfunction' of PSQ was the most severely affected by PSU.</p><p><strong>Conclusions: </strong>Interventions that target regulating negative emotion and reducing daytime tiredness would be more effective in managing problematic smartphone use and improving sleep quality.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"482"},"PeriodicalIF":3.4,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12077027/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143956927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of smartphone addiction and family dynamics in sleep quality among earthquake-affected adolescents.","authors":"Fedli Emre Kılıç, Osman Küçükkelepçe, Fatma Sena Konyalıoğlu","doi":"10.1186/s12888-025-06926-w","DOIUrl":"10.1186/s12888-025-06926-w","url":null,"abstract":"<p><strong>Background: </strong>Smartphone addiction is increasingly prevalent, particularly among younger individuals, and has been linked to poor sleep quality. This study aims to assess the effects of smartphone addiction, usage time, socio-demographic factors, relationship with parents, parents' smartphone usage duration, and earthquake-related experiences on sleep quality among adolescents in the earthquake-affected Kahta district of Adıyaman, Turkey.</p><p><strong>Materials and methods: </strong>A cross-sectional study was conducted between June 1st and July 31st 2024 with 394 adolescents aged 12 to 18. Data were collected using a questionnaire that included socio-demographic variables, the Pittsburgh Sleep Quality Index (PSQI), and the Smartphone Addiction Scale.</p><p><strong>Results: </strong>The prevalence of smartphone addiction was 57.9%, while 66.2% of participants had poor sleep quality. Adolescents using smartphones for more than two hours daily had a higher frequency of poor sleep quality (p = 0.024). Parental influence was significant: participants whose mothers used smartphones for more than one hour daily had a 2.03 times higher risk of poor sleep quality (p = 0.022). Adolescents with poor relationships with parents had a significantly higher risk of sleep disturbances (p < 0.001). Additionally, those who experienced intense fear during the earthquake or lost loved ones showed significantly worse sleep quality (p = 0.007).</p><p><strong>Conclusion: </strong>Smartphone addiction and prolonged usage are strongly associated with poor sleep quality among adolescents. Maternal smartphone use, affects adolescent sleep. Moreover, traumatic experiences related to the earthquake, such as fear and loss, significantly worsen sleep quality. These findings highlight the need for interventions addressing both smartphone addiction and family dynamics to improve sleep health in disaster-affected adolescents.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"481"},"PeriodicalIF":3.4,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12070766/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143952938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding the barriers and facilitators to delivering peer support effectively in England: a qualitative interview study.","authors":"Una Foye, Natasha Lyons, Prisha Shah, Lizzie Mitchell, Karen Machin, Beverley Chipp, Stephen Jeffreys, Tamar Jeynes, Karen Persaud, Vicky Nicholls, Ruth E Cooper, Andrew Grundy, Tamara Pemovska, Nafiso Ahmed, Rebecca Appleton, Julie Repper, Sonia Johnson, Brynmor Lloyd-Evans, Alan Simpson","doi":"10.1186/s12888-025-06850-z","DOIUrl":"10.1186/s12888-025-06850-z","url":null,"abstract":"<p><strong>Background: </strong>Peer support roles within mental health services are rapidly increasing in number and scope in the UK and internationally. This paper explores the facilitators and barriers to delivering peer support effectively, as experienced by Peer Support Workers (PSWs) in a range of services and settings.</p><p><strong>Methods: </strong>We conducted semi-structured qualitative interviews with paid mental health PSWs working across a range of settings in England. We took a collaborative, participatory approach. Interviews were carried out by researchers with experience of living with and/or supporting others with mental health conditions, and for some having experience delivering peer support themselves, and data were analysed using methods guided by general principles of thematic analysis.</p><p><strong>Results: </strong>We interviewed 35 PSWs with a range of roles that spanned a range of mental health areas, and regions. Overarching facilitators and barriers were identified including the need for roles to have flexibility with some structure and boundaries; the need for support, supervision and training to ensure PSWs are skilled in delivering the unique elements of their job; the importance of working with a strong team and leaders who support and value PSW; the complexity of working where there are tensions between the flexibility of PSW and the structures of existing healthcare systems, as well as the systemic factors such as funding, pay and progression can have an effect both on the personal experience of PSWs and on the value placed on PSWs in the wider organisation.</p><p><strong>Conclusion: </strong>Our findings highlight the complexity of peer support work and PSW roles, with a variety both of facilitators allowing them to carry out roles effectively and the barriers to doing so. As PSWs numbers and the scope of their roles increase, awareness of barriers and facilitators needs to inform PSW job roles, support systems and integration into teams and systems.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"480"},"PeriodicalIF":3.4,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12070543/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}