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Linking oral microbiome with mental health: A review. 口腔微生物群与心理健康的关系综述
IF 1.9
Bioinformation Pub Date : 2026-06-30 eCollection Date: 2026-01-01 DOI: 10.6026/973206300223667
Maleha Maleha
{"title":"Linking oral microbiome with mental health: A review.","authors":"Maleha Maleha","doi":"10.6026/973206300223667","DOIUrl":"10.6026/973206300223667","url":null,"abstract":"<p><p>The gut microbiome shapes depression and anxiety, yet the oral microbiome that seeds it daily remains overlooked. Therefore, it is of interest to review on the oral microbiome's role in the gut-brain axis. A reproducible signature emerges: enriched Prevotella with depleted Haemophilus and Rothia. Four pathways connect a dysbiotic mouth to the brain inflammation, bacterial translocation, neurotransmitter signalling and HPA-axis dysregulation. As adults see hygienists more than any other clinician, dental visits could screen, prevent and refer along this axis.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"22 6","pages":"3667-3672"},"PeriodicalIF":1.9,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545881/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perception of smile esthetics in cases managed with orthodontic alignment and prosthetic enhancement. 正畸矫正和假体增强治疗病例中微笑美学的感知。
IF 1.9
Bioinformation Pub Date : 2026-06-30 eCollection Date: 2026-01-01 DOI: 10.6026/973206300223417
Komal Goswami, Rahul Puri Goswami, Seema Rathi, Pranalee Vitthal More, Shraddha Shetti, Doddy Lokanathan Balaji
{"title":"Perception of smile esthetics in cases managed with orthodontic alignment and prosthetic enhancement.","authors":"Komal Goswami, Rahul Puri Goswami, Seema Rathi, Pranalee Vitthal More, Shraddha Shetti, Doddy Lokanathan Balaji","doi":"10.6026/973206300223417","DOIUrl":"10.6026/973206300223417","url":null,"abstract":"<p><p>Smile esthetics plays a crucial role in determining the success of interdisciplinary treatments involving orthodontic alignment and prosthetic enhancement. Therefore, it is of interest to evaluate perceptions of smile esthetics among orthodontists, prosthodontists, general dentists, and laypersons using standardized frontal smile photographs. Hence, a total of 200 observations were assessed using a standardized rating scale, and statistical analysis was performed to compare differences between groups and assess reliability. The results showed significant differences in esthetic perception, with prosthodontists and orthodontists giving higher ratings than general dentists and laypersons. Reliability analysis demonstrated good-to-excellent agreement. Thus, we show that professional background significantly influences aesthetic perception, highlighting the importance of incorporating patient and lay perspectives in interdisciplinary treatment planning.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"22 6","pages":"3417-3420"},"PeriodicalIF":1.9,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545918/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Integrated optic nerve sheath diameter, glasgow coma scale and computed tomography based model for early prediction of clinically significant brain injury in head trauma: A prospective observational study. 综合视神经鞘直径、格拉斯哥昏迷评分和基于计算机断层扫描的模型早期预测头部创伤中临床显著性脑损伤：一项前瞻性观察研究。
IF 1.9
Bioinformation Pub Date : 2026-06-30 eCollection Date: 2026-01-01 DOI: 10.6026/973206300223762
Chandan K Dey, Merin John, Pallavi Shende, Varun Anand, Biraj Majumder, Sudarsan Behera, Ramaswamy N, Klein Dantis, Santosh K Rathia
{"title":"Integrated optic nerve sheath diameter, glasgow coma scale and computed tomography based model for early prediction of clinically significant brain injury in head trauma: A prospective observational study.","authors":"Chandan K Dey, Merin John, Pallavi Shende, Varun Anand, Biraj Majumder, Sudarsan Behera, Ramaswamy N, Klein Dantis, Santosh K Rathia","doi":"10.6026/973206300223762","DOIUrl":"10.6026/973206300223762","url":null,"abstract":"<p><p>Acute head injury requires rapid identification of clinically significant brain injury (CSBI), yet access to CT imaging is often limited, creating challenges in early triage. In this prospective study of 215 head trauma patients, optic nerve sheath diameter (ONSD) and Glasgow Coma Scale (GCS) were evaluated as predictors of CSBI. Patients with CSBI had significantly higher ONSD and lower GCS and both variables independently predicted injury severity. The combined ONSD + GCS model demonstrated better diagnostic performance, clinical utility and calibration than either parameter alone, with ONSD showing a dose-response relationship with CT severity. Thus, data shows the validating a practical bedside risk stratification approach that integrates ultrasound-derived ONSD with GCS to improve CSBI prediction, particularly in resource-limited settings.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"22 6","pages":"3762-3767"},"PeriodicalIF":1.9,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545969/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of periodontal mouthwashes on microbial load and periodontal indices during removable orthodontic treatment. 牙周漱口水对可摘正畸治疗中微生物负荷和牙周指标的影响。
IF 1.9
Bioinformation Pub Date : 2026-06-30 eCollection Date: 2026-01-01 DOI: 10.6026/973206300223319
Shraddha S Gavade, Kiran Suradkar, Amrita Pritam, Sangita Suradkar, Naman Mittal, Sayali Mohile
{"title":"Impact of periodontal mouthwashes on microbial load and periodontal indices during removable orthodontic treatment.","authors":"Shraddha S Gavade, Kiran Suradkar, Amrita Pritam, Sangita Suradkar, Naman Mittal, Sayali Mohile","doi":"10.6026/973206300223319","DOIUrl":"10.6026/973206300223319","url":null,"abstract":"<p><p>Removable orthodontic appliances may increase plaque accumulation and microbial load, yet the effectiveness of periodontal mouthwashes remains unclear. Therefore, it is of interest to evaluate efficacy of periodontal mouthwashes on microbial load and periodontal indices in patients undergoing removable orthodontic therapy. Hence, eighty subjects were divided into groups receiving different mouthwashes, with assessment of plaque index (PI), gingival index (GI) and bleeding index (BI) at baseline and follow-up. Use of antimicrobial mouthwashes resulted in reduced microbial load and improvement in periodontal indices compared to baseline values. Thus, we support periodontal mouthwashes as effective adjuncts for maintaining oral hygiene during removable orthodontic treatment.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"22 6","pages":"3319-3323"},"PeriodicalIF":1.9,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545938/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Materiovigilance: Knowledge, attitude, practice among healthcare professionals in India. 物质警戒：印度卫生保健专业人员的知识、态度和实践。
IF 1.9
Bioinformation Pub Date : 2026-06-30 eCollection Date: 2026-01-01 DOI: 10.6026/973206300223581
Hemlata Verma, Prerna Jasmine Kerketta, Shilpa Jain, Mahendra Soni
{"title":"Materiovigilance: Knowledge, attitude, practice among healthcare professionals in India.","authors":"Hemlata Verma, Prerna Jasmine Kerketta, Shilpa Jain, Mahendra Soni","doi":"10.6026/973206300223581","DOIUrl":"10.6026/973206300223581","url":null,"abstract":"<p><p>Despite 636 Medical Device Monitoring Centers (MDMCs) in India, post-marketing vigilance for medical devices remains less developed than for drugs. An institutional survey among health care professionals (HCPs) including consultants, physicians, nurses and midwives was conducted using a pre-validated electronic questionnaire. Among 107 respondents (36% response rate), 58% had heard of 'materiovigilance', 47.6% knew the MDAE reporting pathway and 14.9% had reported adverse events. Majority 96.2% agreed that MDAE reporting enhances patient safety and 89.2% supported its inclusion in undergraduate medical curricula. HCPs exhibited a positive attitude towards materiovigilance but knowledge gaps and suboptimal reporting persist; training and stronger reporting systems can promote materiovigilance activities and improve patient safety.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"22 6","pages":"3581-3584"},"PeriodicalIF":1.9,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545907/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Salivary cathelicidin LL-37 as a non-invasive biomarker for oral cancer detection. 唾液cathelicidin LL-37作为口腔癌检测的非侵入性生物标志物。
IF 1.9
Bioinformation Pub Date : 2026-06-30 eCollection Date: 2026-01-01 DOI: 10.6026/973206300223421
Thaneja Ravichandran, Harshavardhan B G, Nandhini Ganesan, Sarswathi Gopal K
{"title":"Salivary cathelicidin LL-37 as a non-invasive biomarker for oral cancer detection.","authors":"Thaneja Ravichandran, Harshavardhan B G, Nandhini Ganesan, Sarswathi Gopal K","doi":"10.6026/973206300223421","DOIUrl":"10.6026/973206300223421","url":null,"abstract":"<p><p>Oral squamous cell carcinoma (OSCC) is the predominant form of oral malignancy, with late-stage diagnosis contributing to poor prognosis. Oral potentially malignant disorders (OPMDs) often precede OSCC, underscoring the need for early diagnostic biomarkers. Hence, salivary cathelicidin LL-37 levels were quantified using ELISA in 80 participants. Participants were divided into four groups: OSCC, tobacco- associated OPMDs, non-tobacco-associated OPMDs, and healthy controls. Salivary cathelicidin LL-37 levels increased progressively from healthy controls to OSCC cases (p < 0.001) with 100% sensitivity and 90% specificity. Thus, we show that salivary LL-37 is a reliable, non-invasive biomarker for early detection and monitoring of oral carcinogenesis.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"22 6","pages":"3421-3424"},"PeriodicalIF":1.9,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545870/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative evaluation of chlorhexidine with or without hyaluronic acid on early periodontal wound healing. 氯己定加透明质酸与不加透明质酸对牙周早期创面愈合的比较评价。
IF 1.9
Bioinformation Pub Date : 2026-06-30 eCollection Date: 2026-01-01 DOI: 10.6026/973206300223747
Abhima Kumar, Kousain Sehar, Sabiha Parwaiz, Mohd Irfan, Chahat Puri, Danish Hamid
{"title":"Comparative evaluation of chlorhexidine with or without hyaluronic acid on early periodontal wound healing.","authors":"Abhima Kumar, Kousain Sehar, Sabiha Parwaiz, Mohd Irfan, Chahat Puri, Danish Hamid","doi":"10.6026/973206300223747","DOIUrl":"10.6026/973206300223747","url":null,"abstract":"<p><p>Achieving uncomplicated tissue recovery remains a major challenge after periodontal surgery. Therefore, it is of interest to evaluate the 10 gingivectomy patients presenting with gingival enlargement. Post-operatively, participants used either a combined 0.2% CHX+HA rinse or CHX alone. The CHX+HA cohort exhibited significantly superior early-stage wound healing outcomes. Thus, data shows combining chlorhexidine with hyaluronic acid enhances early periodontal tissue healing.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"22 6","pages":"3747-3751"},"PeriodicalIF":1.9,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545897/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ultrasound-guided quadratus lumborum block versus caudal block for post-operative analgesia in childrens. 超声引导下腰方肌阻滞与尾侧阻滞对儿童术后镇痛的影响。
IF 1.9
Bioinformation Pub Date : 2026-06-30 eCollection Date: 2026-01-01 DOI: 10.6026/973206300223663
Monika Gandhi, Nidhi Sharma, Divya Rana, Shalini Jain
{"title":"Ultrasound-guided quadratus lumborum block versus caudal block for post-operative analgesia in childrens.","authors":"Monika Gandhi, Nidhi Sharma, Divya Rana, Shalini Jain","doi":"10.6026/973206300223663","DOIUrl":"10.6026/973206300223663","url":null,"abstract":"<p><p>Post-operative pain control in children undergoing lower abdominal surgery remains a concern because single-shot caudal analgesia has limited duration. Therefore, it is of interest to compare ultrasound-guided quadratus lumborum block and caudal block in 70 children, with 35 patients each in Group-QL and Group-C. Baseline age and gender distribution were comparable between the groups, with p = 0.580 and p = 0.550 respectively, while time to first rescue analgesia was significantly longer in Group-QL than Group-C (9.60 ± 0.59 h versus 3.37 ± 0.49 h, p = 0.001). Thus, ultrasound-guided quadratus lumborum block provided longer overall Post-operative analgesia, with significant difference in FLACC score at selected Post-operative time points.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"22 6","pages":"3663-3666"},"PeriodicalIF":1.9,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545883/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Crestal bone loss and soft tissue changes in epicrestal versus subcrestal implants: An in vivo study. 上盖与下盖种植体的牙冠骨丢失和软组织改变：一项体内研究。
IF 1.9
Bioinformation Pub Date : 2026-06-30 eCollection Date: 2026-01-01 DOI: 10.6026/973206300223281
Amit Siwach, Sanatomba Thingujam, Anil Sharma, Shrimant Raman, Reenu Sirohi, Shivani Saran
{"title":"Crestal bone loss and soft tissue changes in epicrestal versus subcrestal implants: An <i>in vivo</i> study.","authors":"Amit Siwach, Sanatomba Thingujam, Anil Sharma, Shrimant Raman, Reenu Sirohi, Shivani Saran","doi":"10.6026/973206300223281","DOIUrl":"10.6026/973206300223281","url":null,"abstract":"<p><p>The long-term success of dental implants depends on preservation of crestal bone and peri-implant soft tissue, yet the optimal depth of implant placement remains controversial. Therefore, it is of interest to compare clinical and radiographic outcomes of epicrestal and subcrestal implant placement at baseline, 6 months and 12 months. Groups showed comparable baseline conditions with no significant intergroup differences (p > 0.05), while subcrestal implants showed consistently lower marginal bone loss and probing depths over time. Although intragroup comparisons revealed significant bone loss progression (p < 0.001), all outcomes remained within acceptable clinical success criteria. Thus, we report that subcrestal implant placement offer a biological advantage in peri-implant tissue preservation despite statistically comparable outcomes.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"22 6","pages":"3281-3288"},"PeriodicalIF":1.9,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545888/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative evaluation of spinal versus epidural anesthesia in lower limb orthopedic surgery: Hemodynamic stability and block duration. 下肢骨科手术中脊髓麻醉与硬膜外麻醉的比较评价：血流动力学稳定性和阻滞时间。
IF 1.9
Bioinformation Pub Date : 2026-06-30 eCollection Date: 2026-01-01 DOI: 10.6026/973206300223707
Neetesh Gautam, Narayan Hari Sharma, Irfan Khan
{"title":"Comparative evaluation of spinal versus epidural anesthesia in lower limb orthopedic surgery: Hemodynamic stability and block duration.","authors":"Neetesh Gautam, Narayan Hari Sharma, Irfan Khan","doi":"10.6026/973206300223707","DOIUrl":"10.6026/973206300223707","url":null,"abstract":"<p><p>Regional anesthesia remains essential in lower limb orthopedic surgeries for providing effective intraoperative anesthetic control and post-operative analgesia with fewer systemic side effects. Therefore, it is of interest to evaluate the fifty patients undergoing elective lower limb orthopedic procedures to assess spinal versus epidural anesthesia in relation to hemodynamic stability and block duration. Twenty-five patients received hyperbaric bupivacaine via spinal route and twenty-five received bupivacaine through a lumbar epidural catheter. Spinal anesthesia demonstrated faster onset and denser surgical block but was associated with higher incidence of hypotension and bradycardia. Epidural anesthesia produced slower onset yet maintained better hemodynamic stability along with prolonged post-operative analgesia. Thus, data shows the both techniques are safe and effective, with choice guided by surgical duration, patient profile and post-operative pain management requirements.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"22 6","pages":"3707-3711"},"PeriodicalIF":1.9,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545948/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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