BioinformationPub Date : 2025-06-30eCollection Date: 2025-01-01DOI: 10.6026/973206300211301
Anunitha R, Rashmi G
{"title":"Correlation of diabetic retinopathy with oxidative biomarkers among diabetic patients.","authors":"Anunitha R, Rashmi G","doi":"10.6026/973206300211301","DOIUrl":"10.6026/973206300211301","url":null,"abstract":"<p><p>The correlation between serum uric acid, bilirubin levels and diabetic retinopathy (DR) in 68 patients with diabetes were studied. Higher grades of DR were significantly associated with elevated fasting blood sugar, postprandial blood sugar, HbA1c and serum uric acid levels, while serum bilirubin levels demonstrated an inverse relationship. A majority of patients had diabetes duration of more than one year, emphasizing the role of chronic hyper-glycemia in DR progression. Monitoring serum uric acid and bilirubin may aid in early detection and assessment of DR severity. However, these biomarkers may have limited utility in predicting the initial development of DR.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1301-1303"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449483/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioinformationPub Date : 2025-06-30eCollection Date: 2025-01-01DOI: 10.6026/973206300211559
Jyoti Mani Shankar Pandey
{"title":"Assessing surgical management of corneal perforation in brittle cornea.","authors":"Jyoti Mani Shankar Pandey","doi":"10.6026/973206300211559","DOIUrl":"10.6026/973206300211559","url":null,"abstract":"<p><p>Evaluate a sample of patients who underwent surgical treatment for corneal perforation in brittle cornea by Penetrating keratoplasty and patch graft. In this study, 466 patients experiencing corneal perforation (CP) in brittle corneas that underwent surgery were retrospectively reviewed. They were divided into two categories. Category A: Patients received Penetrating keratoplasty (n= 232). Category B: Patients received patch graft (n=234) Following surgery, patients were evaluated on days one, seven, four, six, and 12 weeks. There was significant improvement in best corrected visual acuity (BCVA), uncorrected visual acuity (UCVA) in both Penetrating keratoplasty and Patch graft procedure for management of corneal perforation in brittle eyes. However, complications were lesser in patch graft method.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1559-1562"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449526/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioinformationPub Date : 2025-06-30eCollection Date: 2025-01-01DOI: 10.6026/973206300211493
Manish Kumar, Ashutosh Patel, Amal Pushp Singh, Sunil Kumar, Narain C M
{"title":"Early versus conventional closure of intestinal stoma: Insights from a tertiary care hospital in India.","authors":"Manish Kumar, Ashutosh Patel, Amal Pushp Singh, Sunil Kumar, Narain C M","doi":"10.6026/973206300211493","DOIUrl":"10.6026/973206300211493","url":null,"abstract":"<p><p>Outcomes of stoma closure surgery (a surgical procedure to reconnect the bowel and close a stoma) in 110 patients at the Department of General Surgery at Netaji Subhas Medical College and Hospital, Patna is of interest. 55 patients in the ECS (early stoma closure) group received treatment within 14-28 days, whereas 55 patients in the CSC (conventional stoma closure) group had treatment after 8-12 weeks. There were fewer complications in the ECS group (44%) than in the CSC group (64%). Thus, problems with stoma closure surgery were less often in ECS (4%) than in CSC (6%). Results suggest that early stoma closure can be performed safely in patients who fit the requirements.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1493-1496"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449540/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Web-based survey on the impact of alveolar bone density on dental implant stability and success rates.","authors":"Shaista Tabasum, Kumari Sweta, Deboleena Saha, Salmoli Ganguly, Surbhi Sinny, Ravindra Singh Narwariya","doi":"10.6026/973206300211346","DOIUrl":"10.6026/973206300211346","url":null,"abstract":"<p><p>The influence of alveolar bone density on dental implant stability and success rates through a web-based survey of Indian dental professionals is of interest to dentists. Findings indicate a significant correlation between low bone density, particularly D4 type and increased implant failure. Cone-beam computed tomography (CBCT) emerged as the preferred diagnostic tool, improving implant outcome predictions. Clinicians adopt various strategies such as under-drilling and bone grafting to mitigate risks in low-density bone. These insights highlight the need for tailored clinical approaches to optimize implant success across diverse patient populations.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1346-1350"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449523/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145112067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"<i>In vitro</i> evaluation of the anti-microbial efficacy of natural root canal irrigants activated with gamma radiation.","authors":"Shrishtee Priya, Harleen Kaur Sohi, Subasish Behera, Priyanka Pandey, Bibyaswan Chakrabarti, Soumyaranjan Nanda, Miral Mehta","doi":"10.6026/973206300211471","DOIUrl":"10.6026/973206300211471","url":null,"abstract":"<p><p>Neem and Tulsi were investigated as natural root canal irrigants with and without gamma radiation activation to evaluate their performance against <i>Enterococcus faecalis</i>. In total, 60 affected teeth were divided into six groups and each group was treated with a different irrigant. Neem that received gamma-irradiation had the top reduction of bacteria (96.5%), followed by Tulsi and sodium hypochlorite. The effectiveness of non-irradiated extracts was moderate, compared to the mild results found from saline. Gamma radiation made herbal irrigants much more effective, showing their potential for use as biocompatible treatments.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1471-1474"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449531/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Magnitude and contributing factors responsible for premature greying of hair: A cross-sectional study.","authors":"Ransingh Tanwar, Abhay Kumar, Vikas Rangare, Chandra Shekhar Jaiswal, Dileep Dandotiya","doi":"10.6026/973206300211658","DOIUrl":"10.6026/973206300211658","url":null,"abstract":"<p><p>The magnitude of PGH and identify modifiable and non-modifiable contributing factors in an academic medical setting is of interest. We recruited 520 consecutive dermatology out-patients. PGH was defined as the presence of ≥5 grey hairs before age 25 in Asians. Nearly one in four young adults attending our teaching hospital had PGH. Genetic predisposition, modifiable lifestyle factors and correctable micronutrient deficiencies independently influenced risk. Thus, we report early behavioural and nutritional interventions integrated into student-health clinics could attenuate the psychosocial burden of PGH.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1658-1661"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449515/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioinformationPub Date : 2025-06-30eCollection Date: 2025-01-01DOI: 10.6026/973206300211385
Padmavathi P, Chirag K Pandya, Samiya Begum, Gnanadesigan Ekambaram, Mahalakshmi B, Sivasubramanian N, Vijayabanu S
{"title":"Comparative study of dyslipidemia among pre and post - menopausal women.","authors":"Padmavathi P, Chirag K Pandya, Samiya Begum, Gnanadesigan Ekambaram, Mahalakshmi B, Sivasubramanian N, Vijayabanu S","doi":"10.6026/973206300211385","DOIUrl":"10.6026/973206300211385","url":null,"abstract":"<p><p>Dyslipidaemia is an independent risk factor for cardiovascular disease in pre and post-menopausal women. Therefore, it is of interest to analyse the lipid abnormality among them. Totally n=214 women were recruited, among them (n=107) were premenopausal and (n=107) were postmenopausal women. The prevalence of dyslipidaemia in our study was 81.77% (n=175). Among premenopausal women 26.1% (n=28) and post menopause 35.5% (n=38) had isolated lipid abnormality whereas mixed dyslipidaemia was 37.3% (n=40) in premenopausal women and 64.4% (n=69) in postmenopausal women. Study shows the complexity of lipid profile variations and suggests the need for age and stage-specific cardiovascular risk assessment.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1385-1390"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449542/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of abutment angulation on the accuracy of closed tray versus open tray implant impressions using noble bio-care active implants.","authors":"Shaik Riyaz Basha, Shravani Dondla, Praveena Channamsetty, Badugu Satyavathi, Satheesh Simha Reddy, Srivani K, Amisha Agarwal","doi":"10.6026/973206300211370","DOIUrl":"10.6026/973206300211370","url":null,"abstract":"<p><p>The influence of abutment angulation on implant impression accuracy by comparing Closed Tray and Open Tray techniques in a clinical setting is of interest to dentists. Hence, a prospective cross-sectional analysis was conducted on 60 patients receiving implant-supported prostheses, stratified by abutment angulation (0°C, 15°Cand 30-45°C). Impressions were made using polyvinyl siloxane and accuracy was quantified via mean MM discrepancy and procedural performance scores. The Open Tray technique demonstrated superior dimensional fidelity (mean discrepancy = 0.46 mm) versus the Closed Tray (0.72 mm), with significantly higher rates of clinically acceptable impressions and procedural efficacy. Logistic regression identified procedural proficiency as a strong predictor of impression precision. These findings underscore the diagnostic superiority of the Open Tray technique, particularly in angulated scenarios, reinforcing its value in enhancing prosthetic accuracy and clinical predictability.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1370-1374"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449511/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioinformationPub Date : 2025-06-30eCollection Date: 2025-01-01DOI: 10.6026/973206300211683
Balaji V R, Manikandan D, Varshiny M D
{"title":"Effect of root conditioning agents on teeth periodontal using Scanning electron microscopy.","authors":"Balaji V R, Manikandan D, Varshiny M D","doi":"10.6026/973206300211683","DOIUrl":"10.6026/973206300211683","url":null,"abstract":"<p><p>Mechanical instrumentation of root surfaces results in the formation of a smear layer that may impede the reattachment of connective tissue. Root conditioning agents are employed to remove the smear layer, expose collagen fibres and facilitate improved tissue regeneration. Therefore, it is of interest to assess the efficacy of five root conditioning agents-20% citric acid, 17% EDTA, 37% phosphoric acid, 250 mg/mL tetracycline hydrochloride and 0.8% hyaluronic acid-using scanning electron microscopy. Tetracycline hydrochloride showed the greatest efficacy, exhibiting a significantly higher number of patent dentinal tubules compared to other agents. Thus, root surface conditioning enhances biocompatibility, promotes fibroblast adhesion and contributes to favourable periodontal healing and successful surgical outcomes.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1683-1688"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449567/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cross-sectional study on surgical site infections and adherence to intraoperative sterile protocols.","authors":"Naveenkumar Viswanathan, Namratha Sivaprasad Dasamantha, Kaushik Nattamai Rameshbabu, Ajeet Saoji, Naveen Javari Thirumalapura Javarashetty, Keerthika Muniasamy","doi":"10.6026/973206300211623","DOIUrl":"10.6026/973206300211623","url":null,"abstract":"<p><p>Despite advancements in surgical care, surgical site infections (SSIs) continue to contribute significantly to postoperative morbidity. Hence, we evaluated 150 surgical cases over six months at a tertiary care center to assess SSI prevalence and intraoperative sterile practice adherence. An overall SSI rate of 12.7% was noted, predominantly in gastrointestinal and emergency surgeries. Key contributing factors included prolonged operation time, inadequate sterilization, and poor adherence to sterile protocols. The findings underscore the need for stringent infection control practices to reduce SSIs and improve surgical outcomes.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1623-1626"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449537/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}