{"title":"<i>In vitro</i> evaluation of the anti-microbial efficacy of natural root canal irrigants activated with gamma radiation.","authors":"Shrishtee Priya, Harleen Kaur Sohi, Subasish Behera, Priyanka Pandey, Bibyaswan Chakrabarti, Soumyaranjan Nanda, Miral Mehta","doi":"10.6026/973206300211471","DOIUrl":null,"url":null,"abstract":"<p><p>Neem and Tulsi were investigated as natural root canal irrigants with and without gamma radiation activation to evaluate their performance against <i>Enterococcus faecalis</i>. In total, 60 affected teeth were divided into six groups and each group was treated with a different irrigant. Neem that received gamma-irradiation had the top reduction of bacteria (96.5%), followed by Tulsi and sodium hypochlorite. The effectiveness of non-irradiated extracts was moderate, compared to the mild results found from saline. Gamma radiation made herbal irrigants much more effective, showing their potential for use as biocompatible treatments.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1471-1474"},"PeriodicalIF":1.9000,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449531/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bioinformation","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.6026/973206300211471","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
Neem and Tulsi were investigated as natural root canal irrigants with and without gamma radiation activation to evaluate their performance against Enterococcus faecalis. In total, 60 affected teeth were divided into six groups and each group was treated with a different irrigant. Neem that received gamma-irradiation had the top reduction of bacteria (96.5%), followed by Tulsi and sodium hypochlorite. The effectiveness of non-irradiated extracts was moderate, compared to the mild results found from saline. Gamma radiation made herbal irrigants much more effective, showing their potential for use as biocompatible treatments.
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