Biomimetics最新文献_第6页

Effect of Axis Change on Shrinkage Rate of 3D-Printed Bioceramic Zirconia Fabricated via Digital Light Processing.

IF 3.4 3区医学

Biomimetics Pub Date : 2025-02-25 DOI: 10.3390/biomimetics10030140

Ju-Young Park, Yoo-Na Jung, Kyoung-Jun Jang, Sang-Kyu Lee, Seong-Won Choi, Yong-Seok Lee, Yunzhi Peter Yang, Kwi-Dug Yun

{"title":"Effect of Axis Change on Shrinkage Rate of 3D-Printed Bioceramic Zirconia Fabricated via Digital Light Processing.","authors":"Ju-Young Park, Yoo-Na Jung, Kyoung-Jun Jang, Sang-Kyu Lee, Seong-Won Choi, Yong-Seok Lee, Yunzhi Peter Yang, Kwi-Dug Yun","doi":"10.3390/biomimetics10030140","DOIUrl":"10.3390/biomimetics10030140","url":null,"abstract":"Isotropic shrinkage is critical for producing dimensionally accurate prostheses using zirconia. However, the anisotropic shrinkage of 3D-printed zirconia limits its utility in clinical applications. We aimed to evaluate the impact of specimen axis alterations on the shrinkage of digital light processing (DLP)-printed zirconia. Cubes measuring 10 × 10 × 10 mm3 (similar in size to molar crowns) and cuboids measuring 10 × 10 × 20 mm (similar in size to a three-unit bridge) were manufactured using a DLP 3D printer. Zirconia specimens were pre-sintered at 1300 °C and 1400 °C. The Z-axis of some specimens was switched to the X-axis before the final sintering procedure. The X-axis, Y-axis, and Z-axis lengths of the green body, pre-sintered block, and fully sintered block were measured using digital calipers. The 3D-printed specimens showed lower shrinkage and higher deviation than the milled specimens, whose shrinkage rate was 26%. The shrinkage rates of the 3D-printed cubic specimens were 19.9% (length), 20.0% (width), and 21.99% (height), while those of the cuboidal specimens were 20.26%, 19.72%, and 21.81%, respectively. For the 3D-printed specimens, which shrink anisotropically during sintering, the axis change step had no significant impact on the shrinkage rate. In all groups, the shrinkage rate along the building direction during printing significantly exceeded that along the gravity direction during sintering.","PeriodicalId":8907,"journal":{"name":"Biomimetics","volume":"10 3","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11940171/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of Torsional Response in Pneumatic Artificial Muscles.

IF 3.4 3区医学

Biomimetics Pub Date : 2025-02-25 DOI: 10.3390/biomimetics10030139

Frank C Cianciarulo, Eric Y Kim, Norman M Wereley

引用次数: 0

Cardiac Cell Membrane-Coated Nanoparticles as a Potential Targeted Delivery System for Cardiac Therapy.

IF 3.4 3区医学

Biomimetics Pub Date : 2025-02-25 DOI: 10.3390/biomimetics10030141

Faprathan Pikwong, Jiraporn Kamsarn, Wattanased Jarisarapurin, Phornsawat Baipaywad, Hansoo Park, Sarawut Kumphune

{"title":"Cardiac Cell Membrane-Coated Nanoparticles as a Potential Targeted Delivery System for Cardiac Therapy.","authors":"Faprathan Pikwong, Jiraporn Kamsarn, Wattanased Jarisarapurin, Phornsawat Baipaywad, Hansoo Park, Sarawut Kumphune","doi":"10.3390/biomimetics10030141","DOIUrl":"10.3390/biomimetics10030141","url":null,"abstract":"Cardiomyopathies, a cause of heart failure, are a predominant cause of death globally and may lead to discernible myocardial abnormalities. Several therapeutic agents were discovered, developed, investigated, and evaluated to save patients' lives and improve their quality of life. The effective administration of drugs improves therapeutic outcomes while reducing side effects. Nanoparticles (NPs) have been utilised for the delivery of therapeutic agents and demonstrate promise in reducing myocardial ischaemia/reperfusion injury. However, significant limitations of NPs include non-specific targeting and immunogenicity. To improve cardiac targeting and biocompatibility, surface modifications using a cardiac cell membrane (cCM) coating on the surface of NPs have been hypothesised. Here, cCMs were isolated from the human ventricular cell line (AC16), and mesoporous silica nanoparticles (MSNs) were synthesised and then coated with cCMs. The cardiac cell membrane-coated mesoporous silica nanoparticles (cCMCMSNs) did not significantly alter the encapsulation efficiency or the release profile of the loaded drug (Rhodamine B) in comparison to MSN. Moreover, cCMCMSNs demonstrated a significantly enhanced distribution of RhB specifically to cardiac cells, compared to other cell types, without causing cytotoxicity. To evaluate immune escape, cCMCMSNs were exposed to activated macrophages, demonstrating that cCMCMSNs were phagocytosed to a lesser extent than MSN. This study demonstrated the synthesis of cardiac cell membranes coated on the surface of nanoparticles as nanomedicine technologies that enhance selective drug delivery to cardiac cells, potentially offering an alternate method for drug administration in cardiovascular diseases.","PeriodicalId":8907,"journal":{"name":"Biomimetics","volume":"10 3","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11940174/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neuromusculoskeletal Control for Simulated Precision Task versus Experimental Data in Trajectory Deviation Analysis.

IF 3.4 3区医学

Biomimetics Pub Date : 2025-02-25 DOI: 10.3390/biomimetics10030138

Jean Mendes Nascimento, Camila Taira, Eric Cito Becman, Arturo Forner-Cordero

{"title":"Neuromusculoskeletal Control for Simulated Precision Task versus Experimental Data in Trajectory Deviation Analysis.","authors":"Jean Mendes Nascimento, Camila Taira, Eric Cito Becman, Arturo Forner-Cordero","doi":"10.3390/biomimetics10030138","DOIUrl":"10.3390/biomimetics10030138","url":null,"abstract":"Control remains a challenge in precision applications in robotics, particularly when combined with execution in small time intervals. This study employed a two-degree-of-freedom (2-DoF) planar robotic arm driven by a detailed human musculoskeletal model for actuation, incorporating nonlinear control techniques to execute a precision task through simulation. Then, we compared these simulations with real experimental data from healthy subjects performing the same task. Our results show that the Feedback Linearization Control (FLC) applied performed satisfactorily within the task execution constraints compared to a robust nonlinear control technique, i.e., Sliding Mode Control (SMC). On the other hand, differences can be observed between the behavior of the simulated model and the real experimental data, where discrepancies in terms of errors were found. The model errors increased with the amplitude and remained unchanged with any increase in the task execution frequency. However, in human trials, the errors increased both with the amplitude and, notably, with a drastic rise in frequency.","PeriodicalId":8907,"journal":{"name":"Biomimetics","volume":"10 3","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11939874/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Biomimetic Flexible Sliding Suction Cup Suitable for Curved Surfaces.

IF 3.4 3区医学

Biomimetics Pub Date : 2025-02-24 DOI: 10.3390/biomimetics10030137

Enhua Cui, Xiangcong Zhou, Yanqiang Liu, Jixiao Xue, Siyuan Xiong, Deyuan Zhang

{"title":"A Biomimetic Flexible Sliding Suction Cup Suitable for Curved Surfaces.","authors":"Enhua Cui, Xiangcong Zhou, Yanqiang Liu, Jixiao Xue, Siyuan Xiong, Deyuan Zhang","doi":"10.3390/biomimetics10030137","DOIUrl":"10.3390/biomimetics10030137","url":null,"abstract":"The sliding suction robots designed for wall-climbing functions could have accuracy defects due to suction cup sealing, friction interference, and surface adaptability. Hence, this work develops a biomimetic, flexible, sliding suction cup suitable for crawling on curved surfaces. Inspired by the hypostomus plecostomus's mouth, we designed a biomimetic low-contact force flow channel structure and a matrix of friction-reducing protrusions along the lip edge of the sliding suction cup. This design reduces frictional resistance on the sliding interface and the flexible nature of the suction cup, allowing it to be used on curved or vertical surfaces of different materials. Several simulation-based optimization analyses and experimental tests are conducted on the biomimetic low-contact force flow channel structure, and various structural design principles are explored for achieving high adhesion and low-contact force. Additionally, a friction reduction model for the matrix structure is designed to verify the effects of parameters such as load, protrusion size, and quantity on the friction coefficient of the matrix structure surface through friction tests. The sliding suction cup prototype presents an average crawling speed of about 0.4 m/s on a horizontal plane and 0.7 m/s for crawling on vertical walls and the inner surface of a cylindrical rail.","PeriodicalId":8907,"journal":{"name":"Biomimetics","volume":"10 3","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11940009/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bio-Stimulated Lower Limb Rehabilitation Robot Semantic Analogy Fit Design.

IF 3.4 3区医学

Biomimetics Pub Date : 2025-02-24 DOI: 10.3390/biomimetics10030134

Tianyi Yao, Hongfei Yu, Zhongzhi Qin, Li Sun, Jiantao Wu

{"title":"Bio-Stimulated Lower Limb Rehabilitation Robot Semantic Analogy Fit Design.","authors":"Tianyi Yao, Hongfei Yu, Zhongzhi Qin, Li Sun, Jiantao Wu","doi":"10.3390/biomimetics10030134","DOIUrl":"10.3390/biomimetics10030134","url":null,"abstract":"In order to solve the problem of insufficient design applicability in the field of lower limb rehabilitation, such as interaction, experience comfort, and modeling color, a biological excitation function system was used to guide the solution of the functional scheme of lower limb rehabilitation products, and the transformation of lower limb rehabilitation products in functional interaction, experience, and morphological color design driven by biological information-driven cross-domain mapping was improved. We used patent knowledge mining to study the product functional requirements of lower limb rehabilitation products. The results were used to screen the required biological prototypes, and the biological incentives were used to guide the design problems. According to the principle of analogy and similarity calculation, the similarity matrix was obtained, and then the strategy was analyzed. Through the analogy of functional system-product technology engineering systems, the engineering relationship between multi-biological and multi-design elements was determined. We realized the biological replacement and upgrading of product functions under biological stimulation to guide the design of lower limb rehabilitation products. The accurate quantitative biological information of multi-biological analogy fit has the significance of optimizing the training effect, improving the operation efficiency, and improving the morphology and modeling of the lower limb rehabilitation product engineering transformation and design. The acquisition rate of the functional design requirements of lower limb rehabilitation products based on text mining reached 95%, and the accuracy of the biological design prototype obtained through similarity calculation was higher than 79%, which verified the feasibility of the accurate bioinformatics design method and improved the rigor of the bioinformatics biomimetic design method.","PeriodicalId":8907,"journal":{"name":"Biomimetics","volume":"10 3","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11940613/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Design and Control of Dual-Segment Multi-Wire Driven Bionic Soft Arm with Integrated Suction Cups.

IF 3.4 3区医学

Biomimetics Pub Date : 2025-02-24 DOI: 10.3390/biomimetics10030133

Zhaosheng Wu, Qiuxuan Wu, Fulin Du, Zikai Zhao, Shoucheng Xiang, Hongkun Zhou, Yanbin Luo, Zhiyuan Hu

{"title":"Design and Control of Dual-Segment Multi-Wire Driven Bionic Soft Arm with Integrated Suction Cups.","authors":"Zhaosheng Wu, Qiuxuan Wu, Fulin Du, Zikai Zhao, Shoucheng Xiang, Hongkun Zhou, Yanbin Luo, Zhiyuan Hu","doi":"10.3390/biomimetics10030133","DOIUrl":"10.3390/biomimetics10030133","url":null,"abstract":"Given the growing complexity of underwater operation tasks, particularly in confined spaces, turbulent environments, and dynamic object manipulation, the limitations of traditional rigid robotic arms are becoming ever more evident. To tackle these challenges, this paper proposes the development of a soft robotic arm modeled after octopus tentacles, incorporating biomimetic suckers. To tackle these challenges, this paper proposes the development of a soft robotic arm modeled after octopus tentacles, incorporating biomimetic suckers. By imitating the functional structure and suction cups of an octopus arm, a soft arm with a dual-segment continuous structure and eight-wire drive control is designed, integrating a flexible suction cup at the distal segment. A three-dimensional, dual-segment eight-wire driven segmented constant curvature motion model is developed to enable precise bending and rotational movements. In underwater grasping experiments, the soft robotic arm exhibited enhanced grasping stability, particularly in underwater environments, where it effectively copes with fluid disturbances and the capture of dynamic objects. This substantially increased the reliability and efficiency of underwater operations.","PeriodicalId":8907,"journal":{"name":"Biomimetics","volume":"10 3","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11940186/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of a Wire-Driven Robotic Fish Based on Double Sine Mechanism.

IF 3.4 3区医学

Biomimetics Pub Date : 2025-02-24 DOI: 10.3390/biomimetics10030136

Qian Yang, Qixin Wang, Zihao Cao, Zeyue Zhao, Ye Chen, Yong Zhong

{"title":"Development of a Wire-Driven Robotic Fish Based on Double Sine Mechanism.","authors":"Qian Yang, Qixin Wang, Zihao Cao, Zeyue Zhao, Ye Chen, Yong Zhong","doi":"10.3390/biomimetics10030136","DOIUrl":"10.3390/biomimetics10030136","url":null,"abstract":"Wire-driven robotic fish can effectively simulate the movement of real fish, but research on high-frequency wire-driven robotic fish is limited. This paper introduces the development of wire-driven robotic fish based on a double-sine mechanism. The appearance of the fish body is designed based on the morphology of tuna, and a mechanism that can support the high-frequency movement of the wire-driven mechanism is designed. The swimming speed and turning performance of the robotic fish are experimentally tested at various swing frequencies. The experimental results show that within the range of 1 to 4 Hz, the swimming speed of the robotic fish with different tail stiffness increases as the frequency increases. However, when the frequency exceeds 4 Hz, the swimming speed decreases. The tail joint with lower stiffness performs better at low frequencies, but as frequency increases, higher stiffness results in better swimming performance. Experimental tests show that the turning radius increases with higher swing frequencies and lower stiffness, resulting in a larger turning radius. This experiment will help to improve the application of high-frequency wire-driven mechanisms in the study of robot fish movement and carry out more in-depth bionic research in the future.","PeriodicalId":8907,"journal":{"name":"Biomimetics","volume":"10 3","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11939951/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quasi-Static and Low-Velocity Impact Response of 3D Printed Plates Using Bio-Inspired Tool Paths.

IF 3.4 3区医学

Biomimetics Pub Date : 2025-02-24 DOI: 10.3390/biomimetics10030135

Muhammed Kamrul Islam, Paul J Hazell, Hongxu Wang, Juan P Escobedo, Harun Chowdhury

{"title":"Quasi-Static and Low-Velocity Impact Response of 3D Printed Plates Using Bio-Inspired Tool Paths.","authors":"Muhammed Kamrul Islam, Paul J Hazell, Hongxu Wang, Juan P Escobedo, Harun Chowdhury","doi":"10.3390/biomimetics10030135","DOIUrl":"10.3390/biomimetics10030135","url":null,"abstract":"The study of biomimetics allows for the creation of various structures inspired by nature. This work investigates the impact of using a bio-inspired tool path for manufacturing porous plates via 3D printing. The Bouligand (or plywood-like) structure is prevalent in several biological components. Structures that mimicked the Bouligand design concerning the tool path were printed and compared to uniform plates produced with a rectilinear pattern through mechanical testing. Quasi-static and dynamic tests were conducted on specimens with infill densities ranging from 25% to 100%. Results indicated that the Bouligand pattern displayed superior specific energy absorption at 75% infill density. This bio-inspired path pattern also provided excellent elongation during quasi-static and dynamic failure-the fracture pattern of the bio-inspired path adhered to the Bouligand structure. In contrast, brittle failure was demonstrated by the specimen with a rectilinear pattern at varying infill percentages, while the bio-inspired pattern enhanced the toughness of the polymer specimens.","PeriodicalId":8907,"journal":{"name":"Biomimetics","volume":"10 3","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11940049/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Polyphenol-Inorganic Sulfate Complex-Enriched Straightening Shampoo for Reinforcing and Restoring Reduced Hair Integrity.

IF 3.4 3区医学

Biomimetics Pub Date : 2025-02-22 DOI: 10.3390/biomimetics10030132

Tae Min Kim, Heung Jin Bae, Sung Young Park

{"title":"Polyphenol-Inorganic Sulfate Complex-Enriched Straightening Shampoo for Reinforcing and Restoring Reduced Hair Integrity.","authors":"Tae Min Kim, Heung Jin Bae, Sung Young Park","doi":"10.3390/biomimetics10030132","DOIUrl":"10.3390/biomimetics10030132","url":null,"abstract":"Conventional hair-straightening methods that use chemical treatments to break disulfide bonds cause severe damage to the hair shaft, leading to weakened hair that is prone to reverting to its curly form in high humidity. Therefore, a unique haircare coating technology is required to protect hair integrity and provide a long-lasting straightening effect. Herein, we designed a hair-straightening technology by integrating a nature-inspired polyphenol-inorganic sulfate (PIS) redox agent into formulated shampoo, which achieves a desirable straightening effect through sulfate-induced disulfide breakage while preserving hair integrity through a polyphenol-reinforced structure. The interaction between polyphenols and residual thiols from the straightening process maintained a long-lasting straight hair structure and hair strength. Ellman's assay showed a lower free thiol content from reductant-induced damaged keratin in PIS shampoo-treated hair than in sulfate-treated hair as the polyphenol-thiol bond was formed through the Michael addition reaction, thereby restoring the natural structure of the hair and enhancing its mechanical properties. Owing to the polyphenol coating, PIS shampoo-treated hair exhibited an antistatic effect and high hydrophobicity, indicating healthy hair. Furthermore, the polyphenol coating effectively scavenged radical oxygen species (ROS) in the hair, thereby improving damage protection. Thus, PIS shampoo offers an alternative approach for effective hair straightening.","PeriodicalId":8907,"journal":{"name":"Biomimetics","volume":"10 3","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11939901/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0