Avian PathologyPub Date : 2025-08-01Epub Date: 2025-05-27DOI: 10.1080/03079457.2024.2443508
Naola Ferguson-Noel, Marianne Dos Santos, Mohammadreza Ehsan, Eniope B Oluwayinka
{"title":"Comparison of the efficacy of <i>Mycoplasma gallisepticum</i> vaccine programmes in chickens.","authors":"Naola Ferguson-Noel, Marianne Dos Santos, Mohammadreza Ehsan, Eniope B Oluwayinka","doi":"10.1080/03079457.2024.2443508","DOIUrl":"10.1080/03079457.2024.2443508","url":null,"abstract":"<p><strong>Research highlights: </strong>Vaccine programmes for <i>Mycoplasma gallisepticum</i> were compared in layer chickens.Vaccine programmes included combinations of live F-strain vaccine and bacterin.All vaccine programmes showed reduced tracheal colonization with challenge strain.Live and bacterin combined significantly reduced lesions compared to other groups.</p>","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":" ","pages":"385-397"},"PeriodicalIF":2.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142827297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Avian PathologyPub Date : 2025-08-01Epub Date: 2025-02-05DOI: 10.1080/03079457.2024.2448498
Páll Gretarsson, Käthe Kittelsen, Randi Oppermann Moe, Ingrid Toftaker, Ida Thøfner
{"title":"Histomorphological characteristics of keel bone maturation and keel bone fractures in laying hens.","authors":"Páll Gretarsson, Käthe Kittelsen, Randi Oppermann Moe, Ingrid Toftaker, Ida Thøfner","doi":"10.1080/03079457.2024.2448498","DOIUrl":"10.1080/03079457.2024.2448498","url":null,"abstract":"<p><p>The keel bone in laying hens is prone to fractures, especially on the caudal third of the keel, which is also the last part to ossify. Keel bone fractures (KBF) typically occur between 25 and 50 weeks of age (WOA). However, the keel is fully ossified at around 40 WOA, suggesting fractures can occur before ossification is complete. To better understand the relationship between KBF and ossification, this descriptive study examined keel bone morphology during maturation. Keel bones from 50 commercial aviary housed Dekalb White laying hens were collected at 10 timepoints from 17-53 WOA and prepared for histological analysis. The samples were stained with haematoxylin and eosin and Safranin O to show cartilage, ossification, bone tissue, and KBF. The results indicated an ossification process similar to endochondral ossification. The degree of ossification varied between individuals of the same age. The age at complete ossification varied from 28-49 WOA. None of the keels from hens aged 53 WOA were fully ossified. Cartilage canals were present in the keel cartilage. Medullary bone was observed in all age groups. Most fractures lacked tissue morphologies typical of high-impact collisions, suggesting the need for further research into the underlying causes. This is the first study to detail keel bone histomorphology in commercial laying hens, providing baseline data for future research.</p>","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":" ","pages":"411-426"},"PeriodicalIF":2.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143188180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Genetic and structural factors contributing to the dominance and persistence of goose astrovirus type 2.","authors":"Peng Jiang, Aolin Li, Hongfu Ma, Yankun Lan, Jiaguo Wang, Xin Wang, Liang Zhao, Qifei Wu, Yong Wang, Xu Guo","doi":"10.1080/03079457.2025.2454416","DOIUrl":"10.1080/03079457.2025.2454416","url":null,"abstract":"<p><strong>Research highlights: </strong>Goose astrovirus type 2 (GoAstV-2) became the dominant strain in China post-2017.GoAstV-2 exhibits weaker codon usage bias, enhancing adaptability across hosts.The stability of GoAstV-2 spike protein reduces mutation needs and selective pressure.GoAstV-2 low spike protein variability supports long-term persistence in host populations.</p>","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":" ","pages":"455-463"},"PeriodicalIF":2.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142999461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Avian PathologyPub Date : 2025-08-01Epub Date: 2025-03-13DOI: 10.1080/03079457.2025.2472838
Federico C Bonorino, Juan Francisco Garcia Marin, Abdelhamid Fares, Nagwa Khaled, Deanna Emmanuel, Raveendra R Kulkarni, Isabel Gimeno
{"title":"Characterization of immunopathological changes in the feather pulp of CVI988-vaccinated pullets challenged with a very virulent plus Marek's disease virus strain.","authors":"Federico C Bonorino, Juan Francisco Garcia Marin, Abdelhamid Fares, Nagwa Khaled, Deanna Emmanuel, Raveendra R Kulkarni, Isabel Gimeno","doi":"10.1080/03079457.2025.2472838","DOIUrl":"10.1080/03079457.2025.2472838","url":null,"abstract":"<p><p>High load of oncogenic Marek's disease virus (MDV) DNA in the feather pulp (FP) as early as 21 days of age is a powerful criterion to predict the outcome of Marek's disease (MD) in apparently healthy chickens. The objective of this study was to elucidate the immunopathological changes in the FP of 21-day-old chickens that had been vaccinated with CVI988 vaccine (healthy), vaccinated and challenged with a very virulent plus (vv+) MDV strain 648A (well protected), or were unvaccinated and challenged with 648A strain (not protected) when compared to uninfected naïve chickens. Oncogenic MDV DNA load, histopathological and immunohistochemical evaluation of the lesions, and immunophenotypic characterization of the infiltrates by flow cytometry were examined. Our results demonstrate that 648A-infected unvaccinated chickens had a significant increase in the percentage of CD3+ T cells, mainly CD4+MHC-II+ cells and CD8+MHC-II+ cells, when compared to all other groups. They also had a significantly decreased number of CD8β+ T cells compared to all other groups. Infection with 648A reduced the percentage of macrophages, not only in the unvaccinated group but also in the CVI988/648A group. In addition, groups that were vaccinated with CVI988, regardless of the challenge status, had higher levels of CD8β+ T cells, suggesting that the vaccine has an enhancing effect on the CTL cells. Our results showed that the load of oncogenic MDV is highly correlated with the infiltration of CD4+MHC-II+ cells and provide further confirmation that FP is indeed an appropriate sample for the early diagnosis of MD.</p>","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":" ","pages":"521-529"},"PeriodicalIF":2.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143522585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Avian PathologyPub Date : 2025-08-01Epub Date: 2025-03-12DOI: 10.1080/03079457.2025.2470754
Yi Jiang, Yufei Tian, Jianwei Han, Xiangnan Wang, Rui Zhang, Xinxin Xu, Xiaoli Ma, Wei Zhang, Chaolai Man
{"title":"CircITSN2-miR-17-5p/20a-5p/20b-5p-<i>PD-L1</i> regulatory network is a potential molecular mechanism of <i>PD-L1</i> gene involving in immune response to IBDV.","authors":"Yi Jiang, Yufei Tian, Jianwei Han, Xiangnan Wang, Rui Zhang, Xinxin Xu, Xiaoli Ma, Wei Zhang, Chaolai Man","doi":"10.1080/03079457.2025.2470754","DOIUrl":"10.1080/03079457.2025.2470754","url":null,"abstract":"<p><strong>Research highlights: </strong><i>PD-L1</i> gene is correlated with IBDV immune response in chickens.<i>PD-L1</i> is a key gene regulating the immune functions of the heart, lung, and proventriculus.CircITSN2-miR-17-5p/20a-5p/20b-5p-<i>PD-L1</i> is a potential mechanism in IBDV immunity.</p>","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":" ","pages":"512-520"},"PeriodicalIF":2.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143466753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Avian PathologyPub Date : 2025-08-01Epub Date: 2025-03-05DOI: 10.1080/03079457.2025.2467122
Piotr Indykiewicz, Marcin Przymencki, Piotr Minias, Dariusz Jakubas, Klaudia Litwiniak, Piotr Zieliński, Tomasz Janiszewski, Radosław Włodarczyk, Mateusz Ledwoń, Jacek Nowakowski, Beata Dulisz, Katarzyna Domańska-Blicharz, Edyta Świętoń, Krzysztof Śmietanka, Dariusz Bukaciński, Monika Bukacińska, Arkadiusz Buczyński, Szymon Beuch, Tomasz Chodkiewicz, Jacek Betleja, Szymon Bzoma, Dominik Marchowski, Arkadiusz Sikora, Łukasz Bednarz, Jacek Antczak, Andrzej Dylik, Zbigniew Kajzer, Wiesław Król, Łukasz Krajewski, Sebastian Menderski, Jan Rapczyński, Sławomir Rubacha, Rafał Szczerbik, Jakub Szymczak, Kazimierz Walasz, Przemysław Wylegała
{"title":"Impact of highly pathogenic avian influenza virus (HPAIV) on Black-headed Gulls <i>Chroicocephalus ridibundus</i> population in Poland in 2023.","authors":"Piotr Indykiewicz, Marcin Przymencki, Piotr Minias, Dariusz Jakubas, Klaudia Litwiniak, Piotr Zieliński, Tomasz Janiszewski, Radosław Włodarczyk, Mateusz Ledwoń, Jacek Nowakowski, Beata Dulisz, Katarzyna Domańska-Blicharz, Edyta Świętoń, Krzysztof Śmietanka, Dariusz Bukaciński, Monika Bukacińska, Arkadiusz Buczyński, Szymon Beuch, Tomasz Chodkiewicz, Jacek Betleja, Szymon Bzoma, Dominik Marchowski, Arkadiusz Sikora, Łukasz Bednarz, Jacek Antczak, Andrzej Dylik, Zbigniew Kajzer, Wiesław Król, Łukasz Krajewski, Sebastian Menderski, Jan Rapczyński, Sławomir Rubacha, Rafał Szczerbik, Jakub Szymczak, Kazimierz Walasz, Przemysław Wylegała","doi":"10.1080/03079457.2025.2467122","DOIUrl":"10.1080/03079457.2025.2467122","url":null,"abstract":"<p><p>The highly pathogenic avian influenza virus (HPAIV) A(H5N1) has caused the most extensive and severe epizootic event affecting both poultry and wild birds globally. This study investigated the impact of HPAIV on the breeding population of the Black-headed Gull <i>Chroicocephalus ridibundus</i>, the most abundant gull species in Poland. During the 2023 outbreak, this species was reported as the most frequently infected in the country. A higher-than-natural adult mortality rate (greater than 1.5% of the breeding individuals) was observed in 114 surveyed colonies across all regions of Poland. Laboratory tests confirmed the presence of HPAIV in all 17 colonies sampled, with average adult mortality estimated at 26.1%, and ranging from 1.7% to 77.8%. The estimated mortality rate across all surveyed colonies was 22.2%. Extrapolations across the entire Polish breeding population (at least 115,000 pairs according to the national census) indicated that approximately 51,000 adult Black-headed Gulls might have perished due to HPAIV in 2023. The number of adults found dead was positively correlated with colony size (<i>r</i> = 0.733, <i>P</i> < 0.001). The deaths were associated with a single HPAIV genotype (BB) across all confirmed cases. Understanding the spread and severity of HPAIV in colonially breeding waterbirds, such as gulls, is essential for assessing the full extent of the threats this virus poses to wild bird populations.</p>","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":" ","pages":"498-511"},"PeriodicalIF":2.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143555730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The host protein CCT8 interacts with PB2 protein of H9N2 AIV and facilitates virus replication.","authors":"Yiqin Cai, Ye Liu, Guihu Yin, Jianing Hu, Zichen Gao, Xinyu Guo, Ruiying Wang, Meng Zhong, Qingtao Liu, Xiuli Feng","doi":"10.1080/03079457.2025.2476511","DOIUrl":"10.1080/03079457.2025.2476511","url":null,"abstract":"<p><strong>Research highlights: </strong>The host protein CCT8 interacts with the influenza virus protein PB2.The CCT8 gene is upregulated during influenza virus infection.Knockdown of CCT8 inhibits viral proliferation.Elevated expression of CCT8 facilitates viral proliferation.</p>","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":" ","pages":"530-540"},"PeriodicalIF":2.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Epidemiological investigation and drug resistance analysis of avian pathogenic <i>Escherichia coli</i> (APEC) of Wenchang chickens in Hainan, China.","authors":"Rui Tian, Feng Xie, Xin Wang, Lei Dai, Jinxiu Wang, Yuqing Liu, Chengxin Zhao, Qingxia Li, Wei Zhang","doi":"10.1080/03079457.2024.2447296","DOIUrl":"10.1080/03079457.2024.2447296","url":null,"abstract":"<p><strong>Research highlights: </strong>Type O8 is the most prevalent serotype of APEC isolated from Wenchang chicken embryos (Hainan, China).The isolates were more than 90% resistant to erythromycin, amoxicillin, ampicillin, and tetracycline.19.2% of the isolates were multi-resistant to more than 14 antibiotics.APEC of the same serotype isolated from Hainan Wenchang embryos have close relationships in the evolutionary tree of the core genome.</p>","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":" ","pages":"398-410"},"PeriodicalIF":2.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142881065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Avian PathologyPub Date : 2025-08-01Epub Date: 2025-02-05DOI: 10.1080/03079457.2025.2457095
Túlio Spina de Lima, Mauro de Mesquita Souza Saraiva, Adriana Maria de Almeida, Taisa Santiago Ferreira, Lucas Bocchini Rodrigues Alves, Viviane Amorim Ferreira, Oliveiro Caetano de Freitas Neto, Paul Andrew Barrow, Angelo Berchieri Junior
{"title":"Deletion of <i>ttrA</i> and <i>pduA</i> genes in <i>Salmonella enterica</i> serovars induce a comparable immune response to wild-type infection in different chicken lineages.","authors":"Túlio Spina de Lima, Mauro de Mesquita Souza Saraiva, Adriana Maria de Almeida, Taisa Santiago Ferreira, Lucas Bocchini Rodrigues Alves, Viviane Amorim Ferreira, Oliveiro Caetano de Freitas Neto, Paul Andrew Barrow, Angelo Berchieri Junior","doi":"10.1080/03079457.2025.2457095","DOIUrl":"10.1080/03079457.2025.2457095","url":null,"abstract":"<p><strong>Research highlights: </strong><i>ttrA</i> and <i>pduA</i> double mutants in <i>Salmonella</i> provoke a similar immune response.SE elicited more intense immune responses than STM.The immune response in the broiler was more intense than in other lineages.</p>","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":" ","pages":"464-475"},"PeriodicalIF":2.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142999459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Avian PathologyPub Date : 2025-08-01Epub Date: 2025-02-24DOI: 10.1080/03079457.2025.2462628
Pornchai Pornpanom, Gediminas Valkiūnas, Surya Paudel
{"title":"Morphological and molecular characterization of avian trypanosomes in domestic chickens (<i>Gallus gallus domesticus</i>) in Southeast Asia and review of the parasite morphometry in different avian hosts.","authors":"Pornchai Pornpanom, Gediminas Valkiūnas, Surya Paudel","doi":"10.1080/03079457.2025.2462628","DOIUrl":"10.1080/03079457.2025.2462628","url":null,"abstract":"<p><strong>Research highlights: </strong>The prevalence of trypanosomes in chickens is high.The first report of <i>Trypanosoma avium</i> in chickens with evidence of species identification.The first report of morphological and molecular characteristics of <i>Trypanosoma calmettei</i>.A cheap and quick buffy coat method is helpful for screening trypanosomes.</p>","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":" ","pages":"489-497"},"PeriodicalIF":2.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143121953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}