Avian Pathology最新文献

{"title":"Apparent discrepancies in the review \"Avian host range of <i>Chlamydophila</i> spp. based on isolation, antigen detection and serology\" by Kaleta, E.F. & Taday, E.M.A. (2003), <i>Avian Pathology</i>, 32, 435-462.","authors":"J Christian Franson","doi":"10.1080/03079457.2023.2225978","DOIUrl":"10.1080/03079457.2023.2225978","url":null,"abstract":"Citing published reports and their own diagnostic data, Kaleta and Taday (2003) (https://doi.org/10.1080/ 03079450310001593613) reported that 469 domestic and free-living bird species were determined to be chlamydia-positive, based on isolation of the organism and antigen detection or on serological detection of circulating antibodies. However, I was unable to reconcile the designation of chlamydia-positive in some of the species listed by Kaleta and Taday (2003) with the information provided in the corresponding references cited. For example, Eddie et al. (1966) tested sera from 24 species of birds in Alaska (see their Table 1) by “direct and indirect complement fixation techniques in the presence of the standard psittacosis antigen.” Eddie et al. (1966) reported that serum samples from only two species reacted, and the authors considered those titres too low to be of diagnostic significance. However, Kaleta and Taday (2003) listed 20 bird species from Eddie et al. (1966) as being positive for chlamydia. Additional apparent discrepancies are listed in Table 1 of the current article.","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10233515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Avian retroviral cardiomyopathy induced by infectious molecular clones of avian leukosis viruses (fowl glioma-inducing virus variants).","authors":"Hayate Nishiura,&nbsp;Aya Tsushima,&nbsp;Azusa Kato,&nbsp;Shun Saito,&nbsp;Takeshi Iwamoto,&nbsp;Yui Kondo,&nbsp;Hitoshi Hatai,&nbsp;Kenji Ochiai","doi":"10.1080/03079457.2023.2215187","DOIUrl":"https://doi.org/10.1080/03079457.2023.2215187","url":null,"abstract":"<p><p>We previously described cardiomyocyte abnormality caused by Km_5666 strain, a variant of fowl glioma-inducing virus (FGV) prototype, which is an avian leukosis virus (ALV). However, the cardiac involvement appeared to be eradicated from the flock after a few years. An epidemiological survey from 2017 to 2020 was performed to elucidate the current prevalence of the cardiopathogenic strains in this flock. Four of the 71 bantams pathologically examined showed both glioma and cardiomyocyte abnormality, from which three ALV strains were detected. DNA sequencing revealed that several different ALV strains coexisted in each bantam and that the conserved Km_5666 virus fluid also contained at least two different ALV strains. We generated three infectious molecular clones from these samples, named KmN_77_clone_A, KmN_77_clone_B, and Km_5666_clone. The <i>env</i>SU of KmN_77_clone_A shared high sequence identity with that of Km_5666 (94.1%). In contrast, the <i>env</i>SU of KmN_77_clone_B showed >99.2% nucleotide similarity with that of an FGV variant without cardiopathogenicity. Furthermore, Km_5666_clone experimentally reproduced both gliomas and cardiomyocyte abnormality in chickens. From these results, it is suggested that the pathogenic determinant of cardiomyocyte abnormality is located in <i>env</i>SU similar to that of Km_5666. The cloning technique described here is beneficial for evaluating the viral pathogenicity in cases where affected birds are coinfected with several different ALV strains.</p>","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9861597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recombinant <i>Fowl aviadenovirus E</i> (FAdV-E) penton base vaccination fails to confer protection against inclusion body hepatitis (IBH) in chickens.","authors":"Carlotta De Luca,&nbsp;Anna Schachner,&nbsp;Michael Hess","doi":"10.1080/03079457.2023.2226085","DOIUrl":"https://doi.org/10.1080/03079457.2023.2226085","url":null,"abstract":"<p><p>Inclusion body hepatitis (IBH) is a metabolic disease affecting chickens, associated with different serotypes of fowl adenovirus (FAdV). Experimentally tested vaccines against IBH include several capsid-based subunit vaccines, but not the penton base protein. In the present study, specific pathogen-free chickens were vaccinated with recombinant penton base expressed from each of two different FAdV serotypes (FAdV-7 and FAdV-8b), followed by challenge with a virulent IBH-causing strain. No protection was observed with either vaccine, possibly due to the low immunogenicity of each protein and their inability to induce neutralizing antibodies in the host.</p>","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9861885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bornaviral infections in Atlantic canaries (<i>Serinus canaria</i>) in Poland.","authors":"Ines Szotowska,&nbsp;Aleksandra Ledwoń,&nbsp;Izabella Dolka,&nbsp;Joanna Bonecka,&nbsp;Piotr Szeleszczuk","doi":"10.1080/03079457.2023.2206801","DOIUrl":"https://doi.org/10.1080/03079457.2023.2206801","url":null,"abstract":"<p><p>The presence of canary bornavirus (<i>Orthobornavirus serini</i>) genetic material was tested in organ samples from 157 Atlantic canaries (<i>Serinus canaria</i>) and four hybrids of Atlantic canary and European goldfinch (<i>Carduelis carduelis</i>). The subjects of the research were samples collected in the years 2006-2022. A positive result was obtained in 16 canaries and one hybrid (10.5%). Eleven positive canaries had neurological signs prior to death. Four of them also had atrophic changes in the forebrain, which have not previously been described in canaries and other species of birds infected with avian bornavirus. In one canary, computed tomography without contrast was performed. This study showed no changes, despite advanced forebrain atrophy found on <i>post-mortem</i> examination of the bird. The organs of the studied birds were also tested with PCR tests for the presence of polyomaviruses and circoviruses. There was no correlation between the bornavirus infection and the presence of the other two viruses in the tested canaries.<b>RESEARCH HIGHLIGHTS</b> The incidence of bornaviral infections in canaries in Poland is relatively low.Non-contrast CT is not a useful method for brain atrophy diagnostic in canaries.Neurological signs were found in the majority of birds infected with bornaviruses.Visceral ganglioneuritis was found in a minority of birds infected with bornaviruses.</p>","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9914788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bart Rispens Award 2023 for the best paper published in <i>Avian Pathology</i> (volumes 50 and 51).","authors":"Nicolas Eterradossi,&nbsp;Damer P Blake","doi":"10.1080/03079457.2023.2225958","DOIUrl":"https://doi.org/10.1080/03079457.2023.2225958","url":null,"abstract":"Following deliberation by the Bart Rispens Research Award Committee, it is our pleasure to announce that the winner of the Bart Rispens Research Award for 2023, representing the best paper published in Avian Pathology in the years 2021 and 2022, is Cameron Ellington for the paper “Characterization of Md5-BAC-REV-LTR virus as Marek’s disease vaccine in commercial meat type chickens: protection and immunosuppression” (Ellington et al., 2021). The topic of the 2023 winning paper is especially relevant given Bart Rispens’ development of the Marek’s disease vaccine strain CVI-988 (or “Rispen(s) vaccine”). Chiharu Hidaka and Surya Paudel were also highly commended, finishing in second and third places, respectively (Hidaka et al., 2021; Paudel et al., 2021). A highlight of the biennial WVPA Congress, the Bart Rispens Research Award is given to the first author of the best paper published in Avian Pathology during the two calendar years preceding the Congress (http://www.wvpa.net/awards.php#bart). The award celebrates the pioneering work of Bart Rispens and is represented by a medal (Figure 1). Supported by MSD Animal Health, the award will be presented at the 22 congress of the WVPA in Verona, Italy (4 8 September 2023, https://www.wvpac2023.com/). The Bart Rispens Research Award Committee extends its congratulations to all authors of the nominated and winning papers.","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9854100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"International Meetings, WVPA Matters and Announcements.","authors":"","doi":"10.1080/03079457.2023.2235141","DOIUrl":"https://doi.org/10.1080/03079457.2023.2235141","url":null,"abstract":"","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9858030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Broiler performance correlates with gut morphology and intestinal inflammation under field conditions.","authors":"Katrien Rysman,&nbsp;Venessa Eeckhaut,&nbsp;Richard Ducatelle,&nbsp;Evy Goossens,&nbsp;Filip Van Immerseel","doi":"10.1080/03079457.2023.2201169","DOIUrl":"10.1080/03079457.2023.2201169","url":null,"abstract":"<p><p>Maintaining optimal gut health is a key driver for a well-performing broiler flock. Histology of intestinal sections and quantification of villus structure can be used to evaluate gut health. While these measurements have been used in experimental models to evaluate gut health, less is known about the associations of these parameters with performance in commercial broiler farms. The objective of the present study was to evaluate possible associations of intestinal villus structure and the inflammatory condition of the gut with Ross 308 broiler performance in 50 commercial farms. On day 28 of the production round, 20 randomly selected broilers per farm were weighed, euthanized, and a duodenal section was collected to determine villus length, crypt depth and the CD3⁺ T-lymphocytes area percentage (CD3⁺ %). We found a relatively low coefficient of variance (CV) for the villus length (between farms; 9.67%, within farms; 15.97%), while the CD3⁺ (%) had a high CV (between farms; 29.78%, within farms; 25.55%). At flock level, the CD3⁺ (%) was significantly correlated with the villus length (<i>r</i> = -0.334), crypt depth (<i>r</i> = 0.523) and the villus-to-crypt ratio (<i>r</i> = -0.480). The crypt depth was significantly correlated with the European production index (EPI) (<i>r</i> = -0.450) and feed conversion ratio (FCR) (<i>r</i> = 0.389). At broiler level, a significant association was found between the individual body weight (day 28), CD3⁺ (%) and villus-to-crypt ratio. These data thus show that gut villus structure is significantly associated with bird performance under commercial conditions. RESEARCH HIGHLIGHTSGut histology parameters vary between and within farms.Broiler performance is associated with gut morphology.</p>","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10231429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Avian Diseases 67.1 Table of Contents.","authors":"","doi":"10.1080/03079457.2023.2235142","DOIUrl":"https://doi.org/10.1080/03079457.2023.2235142","url":null,"abstract":"","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9919488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The protection conferred against virulent Newcastle disease virus (vNDV) genotype VII by commercial double recombinant HVT vaccines and NDV live-attenuated vaccine as prime/boost vaccination regimens in commercial broiler chickens carrying maternally-derived antibodies (MDAs) against NDV.","authors":"Ibrahim Abd Elrahman Ghanem,&nbsp;Tamer Mahmoud Abdullatif,&nbsp;Ola Hassanin","doi":"10.1080/03079457.2023.2211548","DOIUrl":"https://doi.org/10.1080/03079457.2023.2211548","url":null,"abstract":"<p><p>Vaccines against vNDV are readily available and potentially protective; nevertheless, improved vaccination protocols are required to prevent clinical disease and discontinue the spread of the virus. This study assessed the effectiveness of two commercial recombinant herpesvirus of turkey vector vaccines (rHVT-NDV-IBDV) that express the fusion (F) protein of NDV and the virus protein 2 (VP2) of infectious bursal disease virus (IBDV). In commercial broilers with maternally-derived antibodies (MDAs) the efficacy of the rHVT-NDV-IBDV vaccines was evaluated when administered alone, in combination with live-attenuated NDV vaccine at one-day-old, or as part of a prime/boost strategy. The vaccinated birds were challenged with the genotype VIId vNDV strain (NDV/chicken/Egypt/1/2015) at various ages (14, 24 and 35 days). In comparison to sham-vaccinated control birds, the applied vaccination regimens were able to reduce or prevent mortality and virus shedding and clinical disease. Two weeks post-application, the two vector vaccines were serologically reactive with the MDAs and induced protective immune responses against the F protein. In the instance of early challenge at 14 days old, the combination of recombinant rHVT-NDV-IBDV with a live vaccine offered better protection and reduced virus shedding compared to the vector vaccine alone. Boosting with live NDV vaccine at 14 days old increased the protective effect of the vector vaccines and reduced virus shedding and the clinical index after challenge at 24 days old. Both combining and/or boosting with live vaccine together with the vector vaccine provided better protection and minimized virus shedding compared with vaccination with vector vaccine only in the instance of 5-week-old challenge.</p>","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9914805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genetic analysis of infectious bronchitis virus (IBV) in vaccinated poultry populations over a period of 10 years.","authors":"Cornelis J Vermeulen,&nbsp;Remco Dijkman,&nbsp;J J Sjaak de Wit,&nbsp;Berend-Jan Bosch,&nbsp;J A P Hans Heesterbeek,&nbsp;Gerdien van Schaik","doi":"10.1080/03079457.2023.2177140","DOIUrl":"https://doi.org/10.1080/03079457.2023.2177140","url":null,"abstract":"<p><p>Infectious bronchitis virus (IBV) is an avian pathogen from the Coronavirus family causing major health issues in poultry flocks worldwide. Because of its negative impact on health, performance, and bird welfare, commercial poultry are routinely vaccinated by administering live attenuated virus. However, field strains are capable of rapid adaptation and may evade vaccine-induced immunity. We set out to describe dynamics within and between lineages and assess potential escape from vaccine-induced immunity. We investigated a large nucleotide sequence database of over 1700 partial sequences of the S1 spike protein gene collected from clinical samples of Dutch chickens submitted to the laboratory of Royal GD between 2011 and 2020. Relative frequencies of the two major lineages GI-13 (793B) and GI-19 (QX) did not change in the investigated period, but we found a succession of distinct GI-19 sublineages. Analysis of dN/dS ratio over all sequences demonstrated episodic diversifying selection acting on multiple sites, some of which overlap predicted N-glycosylation motifs. We assessed several measures that would indicate divergence from vaccine strains, both in the overall database and in the two major lineages. However, the frequency of vaccine-homologous lineages did not decrease, no increase in genetic variation with time was detected, and the sequences did not grow more divergent from vaccine sequences in the examined time window. Concluding, our results show sublineage turnover within the GI-19 lineage and we demonstrate episodic diversifying selection acting on the partial sequence, but we cannot confirm nor rule out escape from vaccine-induced immunity.<b>RESEARCH HIGHLIGHTS</b>Succession of GI-19 IBV variants in broiler populations.IBV lineages overrepresented in either broiler, or layer production chickens.Ongoing episodic selection at the IBV S1 spike protein gene sequence.Several positively selected codons coincident with N-glycosylation motifs.</p>","PeriodicalId":8788,"journal":{"name":"Avian Pathology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243407/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9586837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}