Artificial Cells, Nanomedicine, and Biotechnology最新文献_第9页

Effective detection of ZnO in nicotine using butterfly wing scales 利用蝴蝶翅鳞有效检测尼古丁中的氧化锌

IF 5.8 3区生物学

Artificial Cells, Nanomedicine, and Biotechnology Pub Date : 2022-04-01 DOI: 10.1080/21691401.2022.2056609

Thanachai Changcharoen, Thidsanu Apiphatnaphakul, Wasupon Watjanavarreerat, K. Locharoenrat

{"title":"Effective detection of ZnO in nicotine using butterfly wing scales","authors":"Thanachai Changcharoen, Thidsanu Apiphatnaphakul, Wasupon Watjanavarreerat, K. Locharoenrat","doi":"10.1080/21691401.2022.2056609","DOIUrl":"https://doi.org/10.1080/21691401.2022.2056609","url":null,"abstract":"Abstract This study aimed to elucidate the optical functions of naturally butterfly wing scales via precise control of morphology as an effective photonic sensor and confirm the content of metal oxide nanoparticles in surrounding nicotine. Metal oxide nanoparticles mixed with nicotine were deposited on the wing scales through the spin-coating method and hence investigated using optical microscopy and spectroscopy. Experimental results demonstrated that absorption intensities of ZnO and TiO2 mixed with nicotine on Danaus genutia were remarkably enhanced. Due to the relatively high concentration of zinc found in e-cigarette aerosol, the intensity of ZnO/nicotine modelled as aerosol adsorption on Danaus genutia, further held a certain linear relationship with the concentration of ZnO. The limit of detection of ZnO was as low as 1 nM. The working mechanism of our sensor was explained through the molecular adsorption after H-bond formation of ZnO/nicotine molecules as high-index materials on the wing scales of Danaus genutia without aggregation. This photonic sensor is an alternative to the present-day methods for the rapid test of ZnO content, which is very simple without complicated instrumentation. Furthermore, our method might become a starting point for the advancement of portable instruments for onsite ZnO detection.","PeriodicalId":8736,"journal":{"name":"Artificial Cells, Nanomedicine, and Biotechnology","volume":"60 1","pages":"87 - 95"},"PeriodicalIF":5.8,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82961087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of tenofovir disoproxil fumarate loaded silver nanoparticle on testicular morphology in experimental type-2 diabetic rats 富马酸替诺福韦二氧吡酯纳米银对实验性2型糖尿病大鼠睾丸形态的影响

IF 5.8 3区生物学

Artificial Cells, Nanomedicine, and Biotechnology Pub Date : 2022-03-27 DOI: 10.1080/21691401.2022.2042009

S. O. Olojede, S. Lawal, A. Dare, E. C. Naidu, C. Rennie, O. Azu

{"title":"Evaluation of tenofovir disoproxil fumarate loaded silver nanoparticle on testicular morphology in experimental type-2 diabetic rats","authors":"S. O. Olojede, S. Lawal, A. Dare, E. C. Naidu, C. Rennie, O. Azu","doi":"10.1080/21691401.2022.2042009","DOIUrl":"https://doi.org/10.1080/21691401.2022.2042009","url":null,"abstract":"Abstract Reproductive derangement and metabolic disorders in human immunodeficiency virus (HIV) infected persons require a nanoparticle delivery system to convey antiretroviral drugs to the anatomical sanctuary such as testis. This study investigated the effects of tenofovir disoproxil fumarate (TDF) loaded silver nanoparticles (AgNPs) on the testicular oxidative stress, inflammatory cytokines and histology in male diabetic rats. Thirty-six Sprague-Dawley rats weighing 230 ± 20 g were randomly divided into diabetic and non-diabetic groups (n = 18). Diabetes was induced using the fructose-streptozotocin (Frt-STZ) rat model. Both groups were further divided into three (n = 6) and administered distilled water, TDF, or TDF-AgNP. Results obtained with the TDF-AgNP administration showed a significant increase (p < .05) in the reduced glutathione and catalase levels. Tumour necrosis factor-alpha and interleukin 6 were reduced in diabetic rats administered TDF-AgNP. More so, administration of TDF-AgNP to diabetic rats improved testicular histoarchitecture in diabetic rats. In addition, diabetic rats administered TDF-AgNP showed a significant reduction (p < .05) in blood glucose levels. TDF-AgNP to diabetic rats enhanced testicular antioxidant enzyme, reduced testicular inflammation, and alleviated structural derangements in the testis. Thus, the application of AgNP to deliver TDF may alleviate testicular toxicity and subsequently cater for neglected reproductive dysfunction during the management of HIV infection.","PeriodicalId":8736,"journal":{"name":"Artificial Cells, Nanomedicine, and Biotechnology","volume":"34 1","pages":"71 - 80"},"PeriodicalIF":5.8,"publicationDate":"2022-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85432975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Prevention of peritoneal adhesions formation by core-shell electrospun ibuprofen-loaded PEG/silk fibrous membrane 核壳静电纺布洛芬聚乙二醇/丝纤维膜预防腹膜粘连的形成

IF 5.8 3区生物学

Artificial Cells, Nanomedicine, and Biotechnology Pub Date : 2022-03-17 DOI: 10.1080/21691401.2021.1883043

S. Nadri, A. Rahmani, S. H. Hosseini, M. Habibizadeh, M. Araghi, Hossein Mostafavi

{"title":"Prevention of peritoneal adhesions formation by core-shell electrospun ibuprofen-loaded PEG/silk fibrous membrane","authors":"S. Nadri, A. Rahmani, S. H. Hosseini, M. Habibizadeh, M. Araghi, Hossein Mostafavi","doi":"10.1080/21691401.2021.1883043","DOIUrl":"https://doi.org/10.1080/21691401.2021.1883043","url":null,"abstract":"Abstract Adhesion bands are pathological fibrous tissues that create in the middle of tissues and organs, often reasons of intestinal obstruction, and female infertility. Here, we explored the anti-adhesive and inflammatory capacities of PEG/silk and Ibuprofen-loaded PEG/Silk core-shell nanofibrous membranes, respectively. The ibuprofen-loaded Silk Fibroin-Poly ethylene Glycol (SF-PEG) core-shell membrane was fabricated by electrospinning and considered in terms of morphology, surface wettability, drug release, and degradation. To reveal the membrane capability for adhesion bands inhibition, the membrane was stitched among the abdominal partition and peritoneum and then evaluated using two scoring adhesion systems. According to results, the fibrous membrane hindered cell proliferation, and the scoring systems and pathology showed that in a rat model, Ibuprofen-loaded PEG/Silk core-shell membrane caused a lightening in post-operative adhesion bands and the low-grade inflammatory reaction in animal models. Collectively, we fabricated new ibuprofen-loaded PEG/SF membranes with anti-adhesion and anti-inflammation properties. Moreover, this core-shell electrospun fibrous membrane has not even now been used to prevent peritendinous adhesion generation.","PeriodicalId":8736,"journal":{"name":"Artificial Cells, Nanomedicine, and Biotechnology","volume":"68 1","pages":"40 - 48"},"PeriodicalIF":5.8,"publicationDate":"2022-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80337941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Trans ethosomal hybrid composites of naproxen-sulfapyridine in hydrogel carrier: anti-inflammatory response in complete Freund’s adjuvant induced arthritis rats 水凝胶载体中萘普生-磺胺吡啶反式杂化复合物:完全弗氏佐剂诱导的关节炎大鼠的抗炎反应

IF 5.8 3区生物学

Artificial Cells, Nanomedicine, and Biotechnology Pub Date : 2022-03-09 DOI: 10.1080/21691401.2022.2047712

Sajeev Kumar Babasahib, Roaddy Well Born, N. M. Raghavendra

{"title":"Trans ethosomal hybrid composites of naproxen-sulfapyridine in hydrogel carrier: anti-inflammatory response in complete Freund’s adjuvant induced arthritis rats","authors":"Sajeev Kumar Babasahib, Roaddy Well Born, N. M. Raghavendra","doi":"10.1080/21691401.2022.2047712","DOIUrl":"https://doi.org/10.1080/21691401.2022.2047712","url":null,"abstract":"Abstract Current treatment for Rheumatoid arthritis (RA) utilizes Disease-modifying antirheumatic drugs, non-steroidal anti-inflammatory drugs or its combination, to decrease joint inflammation. In the present study, naproxen (NAP) and sulfapyridine (SULF) ethosomes were prepared by a thin-film hydration technique using PL90G and cholesterol, later crosslinked with carbopol®934. The ethosomes and ethosomal hydrogel were evaluated for rheological properties, physico-chemical analysis, in vitro and in vivo study. The results show, NAP and SULF ethosomes exhibited an average vesicle size between 251.1 ± 1.80–343.5 ± 3.23 nm and 269.0 ± 1.17–358.8 ± 1.22 nm, respectively, with good stability (zeta potential > 30 mV) and polydispersity index. Differential scanning calorimeter and Fourier transform infrared studies reveal no significant changes in the drug properties of ethosomes. Transmission electron microscopy analysis discloses spherical shape vesicles below 200 nm. The entrapment efficiency of NAP and SULF ethosomes was above 66%, and NAP-SULF ethosomes-hydrogel (EH) exhibited a sustained release effect (>8 h). In vivo studies on NAP-SULF EH shows significant inhibition of inflammation (84.63%), with less paw volume (0.1935 ± 0.08 ml) on induced arthritis Albino Wistar rats, (p < .01). NAP-SULF EH was stable at 25 °C ± 0.5 for 3-months. To conclude, a hybrid composite of NAP-SULF in hydrogel carrier prevents inflammation effectively, and could be novel for trans delivery of drugs in RA. Graphical Abstract","PeriodicalId":8736,"journal":{"name":"Artificial Cells, Nanomedicine, and Biotechnology","volume":"29 1","pages":"59 - 70"},"PeriodicalIF":5.8,"publicationDate":"2022-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84293662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Statement of Retraction. 撤回声明。

IF 5.8 3区生物学

Artificial Cells, Nanomedicine, and Biotechnology Pub Date : 2021-12-01 DOI: 10.1080/21691401.2021.1899427

引用次数: 0

Expression of Concern. 表达关心。

IF 5.8 3区生物学

Artificial Cells, Nanomedicine, and Biotechnology Pub Date : 2021-12-01 DOI: 10.1080/21691401.2021.1899377

引用次数: 0

Expression of Concern. 表达关心。

IF 5.8 3区生物学

Artificial Cells, Nanomedicine, and Biotechnology Pub Date : 2021-12-01 DOI: 10.1080/21691401.2021.1899383

引用次数: 0

Expression of Concern. 表达关心。

IF 5.8 3区生物学

Artificial Cells, Nanomedicine, and Biotechnology Pub Date : 2021-12-01 DOI: 10.1080/21691401.2021.1899387

引用次数: 0

Virus-associated ribozymes and nano carriers against COVID-19. 抗COVID-19病毒相关核酶和纳米载体

IF 5.8 3区生物学

Artificial Cells, Nanomedicine, and Biotechnology Pub Date : 2021-12-01 DOI: 10.1080/21691401.2021.1890103

Beyza Dönmüş, Sinan Ünal, Fatma Ceren Kirmizitaş, Nelisa Türkoğlu Laçin

{"title":"Virus-associated ribozymes and nano carriers against COVID-19.","authors":"Beyza Dönmüş, Sinan Ünal, Fatma Ceren Kirmizitaş, Nelisa Türkoğlu Laçin","doi":"10.1080/21691401.2021.1890103","DOIUrl":"https://doi.org/10.1080/21691401.2021.1890103","url":null,"abstract":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a zoo tonic, highly pathogenic virus. The new type of coronavirus with contagious nature spread from Wuhan (China) to the whole world in a very short time and caused the new coronavirus disease (COVID-19). COVID-19 has turned into a global public health crisis due to spreading by close person-to-person contact with high transmission capacity. Thus, research about the treatment of the damages caused by the virus or prevention from infection increases everyday. Besides, there is still no approved and definitive, standardized treatment for COVID-19. However, this disaster experienced by human beings has made us realize the significance of having a system ready for use to prevent humanity from viral attacks without wasting time. As is known, nanocarriers can be targeted to the desired cells in vitro and in vivo. The nano-carrier system targeting a specific protein, containing the enzyme inhibiting the action of the virus can be developed. The system can be used by simple modifications when we encounter another virus epidemic in the future. In this review, we present a potential treatment method consisting of a nanoparticle-ribozyme conjugate, targeting ACE-2 receptors by reviewing the virus-associated ribozymes, their structures, types and working mechanisms.","PeriodicalId":8736,"journal":{"name":"Artificial Cells, Nanomedicine, and Biotechnology","volume":"49 1","pages":"204-218"},"PeriodicalIF":5.8,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/21691401.2021.1890103","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25423377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

TiO2 nanotubes regulate histone acetylation through F-actin to induce the osteogenic differentiation of BMSCs. TiO2 纳米管通过 F-肌动蛋白调控组蛋白乙酰化，诱导 BMSCs 成骨分化。

IF 4.5 3区生物学

Artificial Cells, Nanomedicine, and Biotechnology Pub Date : 2021-12-01 DOI: 10.1080/21691401.2021.1910282

Yanchang Liu, Zhicheng Tong, Chen Wang, Runzhi Xia, Huiwu Li, Haoran Yu, Juehua Jing, Wendan Cheng

{"title":"TiO2 nanotubes regulate histone acetylation through F-actin to induce the osteogenic differentiation of BMSCs.","authors":"Yanchang Liu, Zhicheng Tong, Chen Wang, Runzhi Xia, Huiwu Li, Haoran Yu, Juehua Jing, Wendan Cheng","doi":"10.1080/21691401.2021.1910282","DOIUrl":"10.1080/21691401.2021.1910282","url":null,"abstract":"Bone integration on the surface of titanium prosthesis is critical to the success of implant surgery. Good Bone integration at the contact interface is the basis of long-term stability. TiO2 nanotubes have become one of the most commonly used modification techniques for artificial joint prostheses and bone defect implants due to their good biocompatibility, mechanical properties and chemical stability. TiO2 nanotubes can promote F-actin polymerization in bone mesenchymal stem cells (BMSCs) and osteogenic differentiation. The possibility of F-actin as an upstream part to regulate GCN5 initiation of osteogenesis was discussed. The results of gene loss and functional acquisition assay, immunoblotting assay and fluorescence staining assay showed that TiO2 nanotubes could promote the differentiation of BMSCs into osteoblasts. The intervention of TiO2 nanotubes can make BMSCs form stronger F-actin fibre bundles, which can drive the differentiation process of osteogenesis. Our results showed that F-actin mediated nanotube-induced cell differentiation through promoting the expression of GCN5 and enhancing the function of GCN5 and GCN5 was a key regulator of the osteogenic differentiation of BMSCs induced by TiO2 nanotubes as a downstream mediated osteogenesis of F-actin, providing a novel insight into the study of osteogenic differentiation on surface of TiO2 nanotubes.","PeriodicalId":8736,"journal":{"name":"Artificial Cells, Nanomedicine, and Biotechnology","volume":"49 1","pages":"398-406"},"PeriodicalIF":4.5,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38920941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0