Basic and Clinical Andrology最新文献

{"title":"Nursing support for testicular sperm aspiration and intracytoplasmic sperm injection in patients with high paraplegia: a retrospective case series.","authors":"Qun Wei, Xia Hong, Yu He, Zilian Wang","doi":"10.1186/s12610-025-00281-2","DOIUrl":"10.1186/s12610-025-00281-2","url":null,"abstract":"<p><strong>Background: </strong>High paraplegia, primarily affecting young men during their reproductive years, often results in ejaculatory dysfunction and infertility. Testicular sperm aspiration (TESA) combined with intracytoplasmic sperm injection (ICSI) offers a viable path to biological parenthood for this population. However, evidence on nursing strategies supporting such procedures is limited. This study aimed to evaluate the clinical and psychosocial outcomes of patients with high paraplegia due to spinal cord injury who underwent TESA-ICSI and explore the effectiveness of specialized nursing interventions.</p><p><strong>Case presentation: </strong>A retrospective case series was conducted on nine male patients with high paraplegia treated at Sir Run Run Shaw Hospital (Zhejiang, China) between January 2021 and October 2023. The mean age of the patients was 31.89 ± 4.83 years, with injury durations ranging from 1 to 13 years. Psychological evaluations using the SAS, SDS, SSRS, and WHOQOL-BREF scales revealed that three patients had anxiety, four had depression, and most had moderate to high social support. The WHOQOL-BREF scores indicated generally good perceived quality of life (score range, 82-91). TESA was performed under local anesthesia, with perioperative nursing measures including bladder management, wound care, and infection prevention. Viable sperm were successfully retrieved in all cases without complications. Eight couples proceeded to ICSI, with viable embryos obtained in all. Six couples achieved pregnancy (66.7%)and live births. One case ended in miscarriage due to trauma, and one couple had no embryos suitable for transfer.</p><p><strong>Conclusion: </strong>Comprehensive nursing interventions, including psychological support, ethical evaluation and procedural adaptations, may facilitate the successful application of TESA-ICSI in men with high paraplegia, highlighting the need for standardized interdisciplinary nursing protocols to optimize fertility outcomes in this underserved population.</p>","PeriodicalId":8730,"journal":{"name":"Basic and Clinical Andrology","volume":"35 1","pages":"34"},"PeriodicalIF":2.0,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12403467/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144940406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seminal 5'tRF-Glu-CTC as a Biomarker for Oligozoospermia and ART Outcome Prediction.","authors":"Neslihan Hekim, Sezgin Gunes, Bulent Ayas, Elzem Nisa Alkan","doi":"10.1186/s12610-025-00283-0","DOIUrl":"10.1186/s12610-025-00283-0","url":null,"abstract":"<p><strong>Background: </strong>Epigenetic mechanisms influencing sperm production and function are closely linked to male infertility. Among these, tRNA-derived fragments have recently been identified as important modulators of cellular stress responses and gene expression. The purpose of this study was evaluate the potential role of 5'tRF-Glu-CTC in the context of assisted reproductive technologies (ART) outcomes by comparing its differential expression in the seminal plasma of oligozoospermic and normozoospermic infertile men.</p><p><strong>Results: </strong>Total RNA was extracted from seminal plasma, and 5'tRF-Glu-CTC expression was measured by qRT-PCR. Sperm DNA fragmentation index (DFI) was assessed via the TUNEL assay. The results revealed significantly elevated 5'tRF-Glu-CTC expression in the oligozoospermic group compared to the normozoospermic group (15.58 ± 4.34 vs. 12.53 ± 4.99; fold change: 1.692; P = 0.024). Sperm DFI showed a significant negative correlation with both the progressive motile sperm (ρ = -0.537, P = 0.015) and the total progressive motile sperm count (ρ = -0.509, P = 0.026). However no significant differences in DFI was observed between the oligozoospermic and control groups (P > 0.05). Analysis of ART outcomes revealed that male partners of couples who achieved pregnancy had lower mean 5'tRF-Glu-CTC expression and DFI, although these differences did not reach statistical significance (P > 0.05).</p><p><strong>Conclusions: </strong>These results suggest that 5'tRF-Glu-CTC might be serve as a potential biomarker and could play a role in the pathophysiology of oligozoospermia.</p>","PeriodicalId":8730,"journal":{"name":"Basic and Clinical Andrology","volume":"35 1","pages":"33"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12400651/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144940432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Shear wave elastography in assessing stiffness and volume of varicocele-affected and normal testes: a systematic review and meta-analysis.","authors":"Lihong Wang, Xiaoqi Huang, Yinman Ding","doi":"10.1186/s12610-025-00282-1","DOIUrl":"10.1186/s12610-025-00282-1","url":null,"abstract":"<p><strong>Background: </strong>Varicocele (VC) is a significant contributor to both primary and secondary male infertility. VC can lead to progressive, time-dependent damage to testicular function, as demonstrated in both animal and human studies. To assess testicular tissue alterations, we conducted the first systematic review and meta-analysis on the effects of VC on testicular stiffness and volume. A literature search was conducted in June 2024 without language or geographic restrictions. The search included the databases PubMed, Embase, and Medline. We reviewed the literature to identify all published clinical trials using shear wave elastography (SWE) to evaluate the stiffness and volume of varicocele-affected and normal testes. The reference lists of the retrieved studies were examined. We conducted a systematic review and meta-analysis.</p><p><strong>Results: </strong>Seven articles, encompassing 1118 testes, were selected from a pool of eighty-seven. The analysis revealed that the stiffness of varicocele-affected ipsilateral testes was higher than that of normal testes (p < 0.05), and the stiffness of normal testes was higher than that of contralateral testes (p < 0.05). Regarding volume, the varicocele-affected ipsilateral testes were smaller than the contralateral testes (p < 0.05), with no significant difference between the contralateral and normal testes (p > 0.05).</p><p><strong>Conclusions: </strong>This meta-analysis indicates that VC impacts the stiffness and volume of both testes. SWE is an effective technique for assessing testes affected by VC, but a large-scale, multicenter randomized controlled study is needed for further confirmation.</p>","PeriodicalId":8730,"journal":{"name":"Basic and Clinical Andrology","volume":"35 1","pages":"32"},"PeriodicalIF":2.0,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12382270/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144940398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microscopic surgery for the repair of painful varicocele- efficacy and predictors of successful outcomes.","authors":"Shayel Bercovich, Hen Hendel, Yossi Ventura, Shay Golan, Shachar Aharony, Ohad Shoshany","doi":"10.1186/s12610-025-00277-y","DOIUrl":"10.1186/s12610-025-00277-y","url":null,"abstract":"<p><strong>Background: </strong>Surgical repair can be offered to patients with scrotal pain of suspected varicocele origin. The estimated success rate of pain resolution is approximately 80%, although recent publications have been inconsistent. Predictive variables for successful outcomes remain contested. The current study aimed to evaluate the efficacy of microscopic repair in resolving varicocele pain and to identify variables that predict successful outcomes.</p><p><strong>Results: </strong>During the study period, microscopic subinguinal varicocelectomy was performed in 59 patients with varicocele-related pain. Grade III left varicocele was present in 36 (61%) patients. The median width of the left varicocele, as measured by ultrasound, was 4.2 mm (IQR 4-5), with reflux identified in 39 (66%) patients. The most common type of pain-dull pain-was present in 39 (66%) patients. Exertional pain and sharp pain were reported by 11 (19%) and 9 (15%) patients, respectively. The median follow-up time was 24 months (IQR 13-35), while 46 (78%) patients were contacted by telephone more than 12 months after surgery. Fifty (85%) patients reported complete pain resolution, while partial resolution and persistent pain were reported by 4 (6%) and 5 (9%) patients, respectively. Two variables that increased the risk of pain persistence were repeat varicocele repair surgery and pain as a secondary or additional indication for surgery. Follow-up time of more than 12 months after surgery reduces the risk of pain persistence.</p><p><strong>Conclusions: </strong>A varicocelectomy is a good option for resolving painful varicocele in most patients, especially those whose only indication for surgery is pain. Repeat varicocele surgery appears to increase the risk of persistent pain. A longer follow-up period (more than 12 months after surgery) increases the chances of pain resolution.</p>","PeriodicalId":8730,"journal":{"name":"Basic and Clinical Andrology","volume":"35 1","pages":"31"},"PeriodicalIF":2.0,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12355884/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144858776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chlorpromazine-tadalafil interaction leading to refractory ischemic priapism and penile prosthesis implantation: a case report.","authors":"Can Arici, Mert Basaranoglu, Selahittin Cayan, Murat Bozlu, Erdem Akbay","doi":"10.1186/s12610-025-00278-x","DOIUrl":"10.1186/s12610-025-00278-x","url":null,"abstract":"<p><strong>Background: </strong>Priapism represents a rare urological emergency characterized by persistent penile erection unrelated to sexual stimulation. Although chlorpromazine-induced priapism has been documented, the synergistic interaction with phosphodiesterase type 5 inhibitors resulting in refractory cases necessitating penile prosthesis implantation constitutes a novel clinical scenario requiring comprehensive documentation.</p><p><strong>Case presentation: </strong>We report a 56-year-old male who developed refractory ischemic priapism following self-administration of oral chlorpromazine for hiccups, taken 24 h after tadalafil 20 mg for erectile dysfunction. The patient had previously experienced a transient priapism episode 10 years earlier following isolated chlorpromazine use, establishing chlorpromazine as the primary etiological agent. Despite comprehensive management including corporal aspiration, intracavernosal sympathomimetic injection, and distal T-shunt creation, the patient developed recurrent priapism requiring penile prosthesis implantation.</p><p><strong>Conclusions: </strong>This case demonstrates compelling evidence of a dangerous chlorpromazine-tadalafil interaction resulting in treatment-refractory priapism. The synergistic pharmacological effects of alpha-adrenergic blockade and phosphodiesterase type 5 inhibition created a severe clinical presentation necessitating immediate penile prosthesis implantation. Healthcare practitioners must recognize this potentially devastating drug interaction and implement preventive measures through comprehensive medication reconciliation and patient counseling.</p>","PeriodicalId":8730,"journal":{"name":"Basic and Clinical Andrology","volume":"35 1","pages":"30"},"PeriodicalIF":2.0,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12351909/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144844294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of tunica albuginea disruption secondary to malleable penile implant fracture: insights into etiology and surgical approach.","authors":"Emad S Rajih","doi":"10.1186/s12610-025-00276-z","DOIUrl":"10.1186/s12610-025-00276-z","url":null,"abstract":"<p><strong>Background: </strong>The tunica albuginea is a key anatomical structure supporting penile implants. Several factors can lead to anatomical penile defects, contributing to penile prosthesis malfunction.The aim is to describe the consequences of malleable penile implant fractures, their contribution to tunica albuginea defects, and management outcomes.</p><p><strong>Results: </strong>All patients underwent malleable device surgery were reviwed retrospectively in our center. We included three patients with malleable penile implant disruption. Two patients underwent concomitant plication corporoplasty (PC) with device replacemen and one patient with device replacement only that showed intact tunica albuginea. The mean age at revision was 71.3 years. All patients achieved device stability and reported successful vaginal penetartion after PC and device replacement, with a median follow-up of 28 months.</p><p><strong>Conclusions: </strong>Malleable penile device fractures are extremely rare findings. They can cause tunica albuginea disruption and tears, compromising penile penetration and device stability. Device replacement combined with PC is an essential component of successful vaginal pentration.</p>","PeriodicalId":8730,"journal":{"name":"Basic and Clinical Andrology","volume":"35 1","pages":"29"},"PeriodicalIF":2.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12315309/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144759031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Social Media and Men's Health: Separating Science from Speculation in Andrology.","authors":"Michael George, Vaibhav Modgil, Ian Pearce, Theodora Stasinou","doi":"10.1186/s12610-025-00275-0","DOIUrl":"10.1186/s12610-025-00275-0","url":null,"abstract":"<p><strong>Background: </strong>Social media has rapidly evolved into a primary source of health-related information. For men with concerns regarding their sexual health or fertility, consulting the internet is often felt to be an accessible first-step in exploring their symptoms. Medical misinformation and over-generalisation online remain a significant concern amongst medical professionals, particularly in the current social media era of virality and sensationalism. This narrative review aims to explore the growing intersection between social media and andrology, with insights into the current medical media landscape and the opportunity to enhance health promotion.</p><p><strong>Methods: </strong>The search strategy applied core search terms central to the scope of the review (such as \"social media\" and \"andrology\") in combination with condition-specific terms (such as \"erectile dysfunction\" or \"testosterone\") using Boolean operators to identify relevant literature within PubMed, which served as the primary electronic database, as well as online websites and social media platforms.</p><p><strong>Results: </strong>Social media consumption is on the rise, with users consuming over two hours daily on average worldwide. Amongst posts, there has been a shift towards highly engaging short-form video content, which is particularly popular with young adults. Social media algorithms reinforce consumption patterns by continuously delivering content based on user engagement: the more an individual interacts with a topic or creator, the more related content appears, creating a self-sustaining feedback loop; this principle underpins the concept of virality and risks the rapid dissemination of inaccuracies online. Key men's health topics such as infertility, erectile dysfunction, testosterone supplementation and semen retention are popular amongst social media posts, amassing millions-to-billions of views depending on the platform. Amongst these posts, there is a high degree of misinformation. Clinicians should be confident in navigating the possible challenges associated with social media.</p><p><strong>Conclusion: </strong>Whilst the growing presence of urologists online may have the potential to counter health-related misinformation, there are barriers inherent to social media platforms that limit the reach and impact of expert voices at present. To leverage the opportunity that social media offers, urologists are required to modernise their approach to communication in order to ensure that accurate health information is both accessible and engaging.</p>","PeriodicalId":8730,"journal":{"name":"Basic and Clinical Andrology","volume":"35 1","pages":"28"},"PeriodicalIF":2.4,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12247255/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144607264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of tadalafil 5 mg on erection and persistent storage lower urinary tract symptoms after transurethral resection of prostate: a randomized controlled study.","authors":"Diaa-Eldin Taha, Hossam Nabeeh, Khaled Magdy Zeinelabden, Elsayed Abdelhalim, Salah Elmekawy, Ibrahem Ismail Samaha, Ahmed Behiry, Ahmed Abd Elmoaty, Tarek Abdelbaky, Ali Ibrahim","doi":"10.1186/s12610-025-00273-2","DOIUrl":"10.1186/s12610-025-00273-2","url":null,"abstract":"<p><strong>Background: </strong>We conducted a double-blind, randomized controlled trial to evaluate the effect of early administration of tadalafil (5 mg once daily) on persistent storage lower urinary tract symptoms (LUTS) and erectile function following transurethral resection of the prostate (TURP). All enrolled patients underwent TURP and were randomly assigned to one of two groups: Group A received tadalafil (5 mg once daily) postoperatively, while Group B received a placebo. Erectile function was assessed using the International Index of Erectile Function-5 (IIEF-5) questionnaire, and LUTS were evaluated using the International Prostate Symptom Score (IPSS). The study was conducted at a tertiary care hospital between May 2021 and October 2022.</p><p><strong>Results: </strong>A total of 195 patients were enrolled and randomized into two groups: Group A (n = 103), which received tadalafil 5 mg once daily, and Group B (n = 92), which received a placebo. The mean ± standard deviation (SD) scores for the International Index of Erectile Function (IIEF-5) in Group A at 1, 3, and 6 months post-TURP were 11.59 ± 1.90, 19.80 ± 1.12, and 20.97 ± 0.72, respectively. In Group B, the corresponding scores were 4.88 ± 0.82, 12.86 ± 1.56, and 15.32 ± 1.28. These differences were statistically significant (P < 0.001). Similarly, the mean ± SD values for the International Prostate Symptom Score (IPSS) in Group A at 1, 3, and 6 months post-TURP were 7.31 ± 1.66, 4.46 ± 0.97, and 2.33 ± 0.69, respectively, compared to 9.62 ± 3.34, 5.40 ± 1.98, and 2.83 ± 1.27 in Group B (P < 0.001). Regarding storage symptom subscores, Group A demonstrated preoperative and postoperative mean ± SD values of 8.63 ± 1.82, 3.05 ± 0.78, 1.63 ± 0.49, and 0.92 ± 0.67 at preoperative, 1, 3, and 6 months, respectively. In contrast, Group B showed corresponding values of 3.22 ± 0.72, 2.48 ± 0.50, and 1.69 ± 0.47. These differences were also statistically significant (P < 0.001).</p><p><strong>Conclusion: </strong>Tadalafil 5 mg daily as monotherapy following TURP can lead to early improvement in erectile function; however, its effect on persistent storage lower urinary tract symptoms (LUTS) post-TURP appears to be modest.</p><p><strong>Trial registration: </strong>Our study has been approved by local ethical committee Kafrelsheikh university(MKSU50-3-1) on 20/5/2021 and by clinical trials (NCT06788704) on 25/1/2025.</p>","PeriodicalId":8730,"journal":{"name":"Basic and Clinical Andrology","volume":"35 1","pages":"27"},"PeriodicalIF":2.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12211002/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144526315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of magnetic stimulation as a non-invasive technique in treating different causes of erectile dysfunction: a prospective cohort study.","authors":"Hasan El-Fakahany, Haythem Bassyouni, Sameh Fayek GamalEl Din, Mahmoud H A Montaser","doi":"10.1186/s12610-025-00272-3","DOIUrl":"10.1186/s12610-025-00272-3","url":null,"abstract":"<p><strong>Background: </strong>Elaboration of alternative therapeutic modality is needed, which should be safer, less costly and with no side effects. Functional Magnetic Stimulator (FMS) is a technique that was approved by the US Food and Drug Administration in 1998. We aimed to evaluate the efficacy of FMS in treating different causes of erectile dysfunction (ED).</p><p><strong>Results: </strong>The mean baseline 15 items of the international index of erectile function (IIEF-15) scores of groups A (arteriogenic ED), B (veno-occlusive ED) and C (psychogenic ED) were 12.8 ± 2.6, 16.2 ± 3.3 and 27.5 ± 3.7, respectively. The mean post sessions IIEF-15 scores of groups A, B and C were 23.4 ± 4.1, 31.5 ± 3.5, 49.2 ± 3.5, respectively. The mean baseline domains of erectile function (EF) scores of groups A, B and C were 3.8 ± 2, 5.8 ± 3.5 and 11.5 ± 3.1, respectively. The mean post sessions domains of EF scores of groups A, B and C were 10.6 ± 3.1, 15 ± 3.6 and 24.8 ± 2.9, respectively. The mean baseline domains of orgasmic function scores of groups A, B and C were 3.3 ± 0.9, 3.9 ± 0.5 and 4.8 ± 0.4, respectively. The mean post sessions domains of orgasmic function scores of groups A, B and C were 4.8 ± 0.8 5.9 ± 1.0 and 8.6 ± 0.5, respectively. The mean baseline domains of sexual desire scores of groups A, B and C were 2.6 ± 0.6, 3.1 ± 0.7 and 4.8 ± 0.7, respectively. The mean post sessions domains of sexual desire scores of groups A, B and C were 3.6 ± 0.5, 4.4 ± 0.7 and 6.6 ± 0.6, respectively. The mean baseline domains of intercourse satisfaction scores of groups A, B and C were 1.9 ± 0.5, 2.4 ± 0.6 and 4.1 ± 0.6, respectively. The mean post sessions domains of intercourse satisfaction scores of groups A, B and C were 2.6 ± 0.5, 3.6 ± 0.5 and 5.5 ± 0.6, respectively. The baseline domains of overall satisfaction scores of groups A, B and C were 1.1 ± 0.3, 1.1 ± 0.3 and 2.4 ± 0.7, respectively. The mean post sessions domains of overall satisfaction scores of groups A, B and C were 2 ± 0.7, 2.7 ± 0.7 and 3.8 ± 0.7, respectively.</p><p><strong>Conclusions: </strong>All patients showed significant improvement regarding domains of the IIEF-15 especially psychogenic cases following the sessions of FMS. Future studies should demonstrate the impact of these sessions on the response of poor responders to phosphodiesterase inhibitors and intracorporeal injections.</p>","PeriodicalId":8730,"journal":{"name":"Basic and Clinical Andrology","volume":"35 1","pages":"26"},"PeriodicalIF":2.4,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12180250/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144332405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sexual dysfunction and quality of life in males with genital warts.","authors":"Mohamad M Elhamady, Rabie B Atallah, Osama A Hashem, Mahmoud A Abdelaty, Mohamed L Elsaie","doi":"10.1186/s12610-025-00274-1","DOIUrl":"10.1186/s12610-025-00274-1","url":null,"abstract":"<p><strong>Background: </strong>Genital warts caused by human papillomavirus, significantly impact male sexual function and quality of life. However, the extent of dysfunction varies across studies, necessitating further investigation. This study aims to assess sexual dysfunction and quality of life in men with GWs.</p><p><strong>Results: </strong>A cross-sectional study was conducted among men diagnosed with GWs. Sexual function was evaluated using the International Index of Erectile Function while the Dermatology Life Quality Index measured quality-of-life impairment. Data were analyzed to determine the severity and distribution of dysfunction across domains. Erectile dysfunction was prevalent, with a mean International Index of Erectile Function score of 14.3 ± 4.2, indicating moderate dysfunction. Orgasmic satisfaction (5.8 ± 2.1) and overall satisfaction (6.5 ± 2.4) were also moderately affected. Quality of life was significantly impaired, with 36.7% experiencing moderate impact, 26.7% reporting a very large impact, and 8% suffering an extreme impact.</p><p><strong>Conclusion: </strong>Genital warts contribute to substantial sexual dysfunction and diminished quality of life. The results highlight the need for routine sexual health assessments and psychological support. Integrating medical and psychosocial care may improve patient outcomes.</p>","PeriodicalId":8730,"journal":{"name":"Basic and Clinical Andrology","volume":"35 1","pages":"25"},"PeriodicalIF":2.4,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12177989/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144324421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}