The South Dakota journal of medicine and pharmacy最新文献

{"title":"Relationship between endoscopic gastric atrophy according to Kimura - Takemoto classification and histopathological characteristics in H. Pylori infected patients","authors":"Nam Phan Trung, Thuong Nguyen Thi Huyen","doi":"10.34071/jmp.2023.1.12","DOIUrl":"https://doi.org/10.34071/jmp.2023.1.12","url":null,"abstract":"Background: Endoscopic gastric atrophy according to Kimura-Takemoto classification has been shown to be closely related to histopathological atrophy. Gastric atrophy and intestinal metaplasia are considered precancerous gastric lesions that need to be assessed and monitored for early detection of dysplasia and cancer, especially in H. pylori infected patients. The aim of this study was to evaluate the associations between these endoscopic atrophy according to Kimura - Takemoto classification and pathologic characteristics.\u0000\u0000Methods: A cross-sectional study was conducted in 72 dyspepsia patients at Hue University of Medicine and Pharmacy Hospital, assigned endoscopic assessment and testing H. pylori positive. Assessing endoscopic gastric atrophy according to Kimura-Takemoto classification and compared with histopathological precancerous lesions (atrophy, intestinal metaplasia, dysplasia) according to the modified Sydney system.\u0000\u0000Results: The mean age was 55.6 ± 13.13, male/female ratio was 1.4/1.0. The rate of endoscopic gastric atrophy at stage C1 was 37.5%, C2: 40.3%, C3: 9.7%, O1: 11.1% and O3: 1.4%. On histo-pathology, the rate of gastric atrophy in antrum was 81.9%, in both antrum and body: 16.7%. The rate of intestinal metaplasia in antrum, body, both antrum and body was 36.1%, 2.5% and 11.1%, respectively. The rate of low-grade dysplasia 12.5% (9/72), high-grade dysplasia 6.9% (5/72) and 2 cases of early gastric cancer. Endoscopic gastric atrophy stages C2 and C3 had a higher rate of atrophy on histopathology than stage C1 (91.7% vs 63%) and stages O had a higher rate of intestinal metaplasia than stages C (77.8% vs 30.2%) with p < 0.05.\u0000\u0000Conclusion: The degree of endoscopic gastric atrophy was related to the degree of histopathologic atrophy and intestinal metaplasia, the more severe the stage of endoscopic gastric atrophy, the higher the frequency of atrophy and metaplasia on histopathology. Evaluation of endoscopic gastric atrophy according to Kimura-Takemoto classification is a relatively simple strategy for monitoring for each patient with H. pylori chronic gastritis to detect dysplasia and early cancer.\u0000\u0000\u0000Key words: Atrophic gastritis, H. pylori, Kimura-Takemoto classification","PeriodicalId":86274,"journal":{"name":"The South Dakota journal of medicine and pharmacy","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78866408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum electrolyte disorders in asphyxiated neonates","authors":"Binh Nguyen Thi Thanh, Thao Nguyen Thi Phuong, Thang Tran Binh","doi":"10.34071/jmp.2023.1.6","DOIUrl":"https://doi.org/10.34071/jmp.2023.1.6","url":null,"abstract":"Background: Perinatal asphyxia is one of common causes of neonatal morbidity and mortality. Disorders of electrolytes are more common in the immediate postnatal period and could affects the outcomes of neonates significantly. Therefore, we conducted this study with specific aims to describe the electrolyte status in asphyxiated neonates and find out several factors associated to electrolyte disorders in asphyxiated neonates.\u0000\u0000Methods: This was a cross-sectional descriptive study carried out with 80 asphyxiated neonates admitted at the Neonatal Intensive Care Unit in Hue Central Hospital, Hue City, from April 2021 to August 2022.\u0000\u0000Results: In asphyxiated neonates, average serum value of sodium, potassium, calcium were 136.6; 4.8 and 1.1 mmol/l, respectively. 62.5% asphyxiated neonates had electrolyte disorders. Hypocalcemia was the most common disorder with 37.5%, followed by hyponatremia (32.5%). Hyperkalemia was accounted for 13.7%. We observed the higher hyponatremia and hyperkalemia in severe asphyxia than in moderate asphyxia. Apgar score less than 7 at 5 minutes was associated with the increased risk of hyponatremia and hyperkalemia (odd ratio:8.9; 29.3, respectively with p < 0.01). There was the correlation of Apgar score at 5 minutes with sodium and potassium on the asphyxiated neonates (rs = 0.3 and rs = - 0.6, respectively with p < 0.05).\u0000\u0000Conclusion: Electrolyte disorders are common in asphyxiated neonates. The common types of electrolyte disorders in asphyxiated neonates were hyponatremia and hyperkalemia, hypocalcemia.\u0000\u0000Key words: hyperkalemia, hyponatremia, hypocalcemia, asphyxiated neonates.","PeriodicalId":86274,"journal":{"name":"The South Dakota journal of medicine and pharmacy","volume":"150 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79478357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associated risk factors of type 2 Diabetes mellitus developments in the next 10 years using the FINDRISC among residents aged 25 and over in some wards of Hue city","authors":"Thuoc Doan Phuoc, Huong Nguyen Thi, Linh Phan Thi Thuy, Hang Nguyen Thi Thuy, Huy Le Duc, Nhi Nguyen Thi Hong, Thao Nguyen Thi Phuong, Long Doan Pham Phuoc","doi":"10.34071/jmp.2023.1.17","DOIUrl":"https://doi.org/10.34071/jmp.2023.1.17","url":null,"abstract":"Background: Diabetes is a common disease, with a rapidly increasing trend in Vietnam and worldwide, and is also the leading cause of death, morbidity, and health burden. Therefore, it is important to predict increasing levels of type 2 Diabetes mellitus (T2DM) risk and its associated risk factors to improve prevention strategies. The purpose of our study is to predict the risk of T2DM development and explore its associated factors among individuals aged 25 and above in Hue City.\u0000\u0000Materials and method: A cross-sectional study was carried out on 732 residents, aged 25 and above, living in some wards of Hue City.\u0000\u0000Results: In Tay Loc ward and Thuan Hoa ward of Hue City, the estimated incidence of T2DM development using the ModAsian FINDRISC scale was 5.18%. According to the ModAsian FINDRISC scale, occupational, history of hypertension, and dyslipidemia were significant factors associated with the risk of developing T2DM in the next ten years.\u0000\u0000Conclusion: The intervention strategy of addressing associated risk factors would be essential to reducing the risk of T2DM in the community.\u0000\u0000Key words: Diabetes mellitus, FINDRISC, Hue city.","PeriodicalId":86274,"journal":{"name":"The South Dakota journal of medicine and pharmacy","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84807901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical, endoscopic, histopathological characteristics of patients with colorectal polyps - Endoscopy Gastroenterology Center, Hue University of Medicine and Pharmacy Hospital","authors":"Ha Nguyen Van Thu, Ngoc Nguyen Phan Hong","doi":"10.34071/jmp.2022.7.12","DOIUrl":"https://doi.org/10.34071/jmp.2022.7.12","url":null,"abstract":"Background: Colorectal polyps are a relatively common diseases in the group of lower gastrointestinal tract diseases. The prevalence of colorectal polyps ranges from 20 to 50%. Polyps are formed due to excessive hyperplasia of the mucosa and the malignancy rate of colorectal polyps is higher than other sites. Objectives: (1) To describe some clinical and endoscopic features of colorectal polyps; (2) To evaluate the histopathological characteristics and the relationship between histopathology and some clinical and endoscopic features of colorectal polyps. Subjects: The patients aged 16 years old and older who were diagnosed with colon polyps at the Center for Gastroenterology - Endoscopy at Hue University of Medicine and Pharmacy Hospital from April 1st, 2020 to March 30th, 2021. Methods: Cross-sectional, retrospective description. Results: Study on 67\u0000patients who were dianosiged as having colorectal polyps through endoscopy, in which, 48 patients underwent polypectomy and histopathology. The mean age is 55.8 ± 15.7 years old, the most common age group is ≥ 45 years old, male/female is 2/1. The time from symptoms onset to disease detection is usually 6 months to less than 1 year (37.4%). The common clinical symptoms: abdominal pain (83.6%), diarrhea (29.9 %), constipation (28.4%), dysentery syndrome (13.4%), bloody stools (31.3%). The position of polyps: anus (1.5%), rectum (47.8%), sigmoid colon (40.3%), descending colon (31.3%), transverse colon (22.4%), ascending colon (28.4) %), cecum (13.4%). The proportion of patients having ≥ 2 polyps (59.7%), 1 polyp (40.3%). Polyp sizes: 5 - < 10 mm (50.7%), < 5 mm (37.4%), ≥ 10 mm (11.9%). The percentage of sessile polyps is higher than that of pedunculated polyps at each locations. Histopathological types: adenomatous polyps (60.4%), hyperplastic polyps (20.8%), malignant polyps (4.2%). Polyps with dysplasia (64.6%), mild – grade dysplasia (56.3%), severe-grade dysplasia (8.3%). The differences were statistically significant between the grade of dysplasia and the polyp size groups, between the histopathology and the grade of dysplasia (p < 0.05). Conclusions: Colorectal polyps are more\u0000common in patients ≥ 45 years old, male are much more of having than female. Abdominal pain, bloody stools are common symptoms. Common polyp phenotypes are sessile polyps, ≥ 2 polyps, 5 - < 10 mm in size, mainly in the rectum. Adenomatous polyps are the most common histopathological type, with the high rate of dysplasia.\u0000Key words: clinical, endoscopy, histopathology, colorectal polyps.","PeriodicalId":86274,"journal":{"name":"The South Dakota journal of medicine and pharmacy","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79021865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of colour improvement and stability of white spot lesions following infiltration, micro-abrasion, or CPP-ACP treatments in vitro","authors":"Chi Phan Anh, Linh Le Thi Nhat, An Dang Khac","doi":"10.34071/jmp.2022.7.20","DOIUrl":"https://doi.org/10.34071/jmp.2022.7.20","url":null,"abstract":"Objective: The objective was to compare the colour improvement of white spot lesion and the colour stability of treated enamel to after discolouration in vitro. Method: Artificial WSLs (2 * 2 mm) were created on the outer surface of 60 permanent premolars and randomly allocated to 4 groups. Specimens were treated with infiltration (RI), CPPACP (CPP), and micro-abrasion (MA) or remained untreated (UT).Groups were discoloured for 24 hours in tea or tea + citric acidVisible colour changes (ΔE) were measured spectrophotometrically on following time points: immediately after lesion formation, immediately after treatment, after 30 days of immersion in artificial saliva, anh aftere discolouration. Data were analyzed using SPSS 20 software. Results: WSL formation increased in all groups. ΔE1 is creater 3.7 in all groups but only infiltration reduced this effect to baseline. Highest ΔE4was obtained by CPP-ACP and resin infiltration is lowest. Between the RI and MA treatment groups, ΔE4 did not differ significantly. The improvement was more stable for infiltration and micro abrasion during discolouratio compare to the others (ΔE4 < 3.7). Conclusions: The method of infiltration improves the aesthetics of white spot lesions immediately after treatment and maintains treatment results during the follow-up period. Micro abrasion improved white spot aesthetics during the follow-up period. These two methods WSLs were stable following discolouration challenge.\u0000Key words: white spot lesion, infiltration, micro abrasion, CPP-ACP","PeriodicalId":86274,"journal":{"name":"The South Dakota journal of medicine and pharmacy","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79614456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research application of endoscopic ultrasound - fine needle aspiration in diagnosis pancreas tumors","authors":"Khanh Vinh, Huy Trần Văn","doi":"10.34071/jmp.2022.7.8","DOIUrl":"https://doi.org/10.34071/jmp.2022.7.8","url":null,"abstract":"Background: Pancreatic diseases is very multiform and complex, in which pancreatic tumors have often poor prognosis, especially pancreatic cancer. Early detection and diagnosis of pancreatic tumors have great significance in improving the quality of treatment and prognosis for patients. Endoscopic ultrasound has the advantage of high-frequency ultrasound, an optimal approach to provide a possibility of EUS-FNA. This is important evidence to confirm the diagnosis, guide to treatment and prognosis. This study was aimed at: (1) To describe the characteristics of the pancreatic tumor by endoscopic ultrasound; (2) To evaluate the efficacy and safety of endoscopic ultrasound fine needle aspiration in the diagnosis of pancreatic tumors. Subject and methods: Cross-sectional study concludes 41 pancreatic tumor patients, which indicated endoscopic ultrasound fine needle aspiration in Gastroenterology - Endoscopy Center, Hue University of Medicine and Pharmacy Hospital from 2/2010 to 10/2022. Results: The size of the tumor was more than 2cm, tumors in the pancreatic head accounted for 80.5% and solid tumors accounted for 80.5%. Besides, the main pancreatic duct dilatation accounts for 39.0%, the biliary tract dilatation accounts for 46.3%, pancreatic tumor invades adjacent organs accounts for 29.3%, vascular invasion accounts for 24.4%, with lymph nodes accounting for 51.2%. Endoscopic ultrasound-guide fine needle aspiration pancreatic tumor was performed in 37/41 cases (90.3%). Pathological of pancreatic tumor: pancreatic cancer is highest about 59.5%, benign pancreatic tumors accounted for 10.8%, mucinous cysts accounted for 5.4% and pancreatic tuberculosis accounted\u0000for 2.7%. The complication rate of the procedure was 5.4%. Conclusion: Endoscopic ultrasound fine needle aspiration pancreatic tumors showed relative safety and efficacy, the technical failure rate is very low \u0000Key words: Pancreatic tumor, Endoscopic ultrasound fine needle aspiration","PeriodicalId":86274,"journal":{"name":"The South Dakota journal of medicine and pharmacy","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83635919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heath risk behaviours among adolescents in central of Vietnam: a cross sectional study","authors":"Duc Ton Nu Minh, Ha Thuy Tran Thi, Bao Ha Van Anh, Trang Ho Thi Thuy, Hai Mai Ba, Nguyet Tran Thi, Binh Vo Thi Diem, Ha Hoang Thi Viet, Huy Nguyen Vu Quoc, Phuong Nguyen Thi Anh","doi":"10.34071/jmp.2022.7.6","DOIUrl":"https://doi.org/10.34071/jmp.2022.7.6","url":null,"abstract":"Background: Adolescence is vulnerable subjects and faces many risks that greatly impact their health and development in the future, but adolescents are not really getting the proper care from the health care system. This study aimed to examine the prevalence of health risk behaviours among adolescents in Thua Thien Hue Province, Vietnam, and to determine related factors to adolescents’ health risk behaviours. Materials and Methods: A descriptive cross-sectional study was conducted on 934 adolescents in Thua Thien Hue province, with a multi-stage sampling method. The Youth Risk Behaviour Survey of the Center for Disease Control and Prevention was used for data collection in this study. The SPSS 20.0 software was used to analyse data. Results: The proportion of overweight-obesity adolescents accounted for 14.6%. The prevalence of adolescent\u0000bullying was 14.0%, the higher the adolescent high, the lower the risk of bullying (OR=0.981, p=0.03). The proportion of smoking was low (2.8%), while the alcohol use rate accounted for 10.0%. Adolescents in high school have a higher risk of smoking and alcohol use than those in secondary school. The proportion of adolescents who attempted suicide was slightly high (16.0%). Adolescents who felt lonely, whose parents did not know what the adolescent did in their free time, and does not respect them were several factors that increase suicide intention. Conclusions: School adolescent violence, overweight-obese status, alcohol use, smoking, and suicide intention are health problems occurring among adolescents in Thua Thien Hue. Besides, the feeling of loneliness increases the risk of suicide intention. Adolescents need to receive proper attention from their parents, as well as the healthcare system.\u0000Key words: Adolescent; health-risk behaviours; Thua Thien Hue province","PeriodicalId":86274,"journal":{"name":"The South Dakota journal of medicine and pharmacy","volume":"452 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76547835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Update on the drug treatment of hypertension: perspectives in clinical pharmacology","authors":"Chuyen Le, Nhi Nguyen Thi Lan, Diep Do Thi Hong, Tin Nguyen Thanh, Van Nguyen Le Hong","doi":"10.34071/jmp.2022.7.2","DOIUrl":"https://doi.org/10.34071/jmp.2022.7.2","url":null,"abstract":"Drug therapy to achieve the recommended target blood pressure remains the cornerstone of the management of hypertension. Today, there are strong evidences from randomized controlled trials that antihypertensive drugs are more effective than placebo at reducing cardiovascular mortality and morbidity. According to more recent guidelines, there are three main classes of drugs that have been used for initial monotherapy: inhibitors of the renin-angiotensin system, calcium channel antagonists, and diuretics. The use of beta blockers has been restricted for initial monotherapy in the absence of a specific indication associated with adverse effects on some outcomes, particularly in older patients. Many studies have demonstrated that antihypertensive agent classes can be combined effectively and nowadays, it is strongly recommended to use single-pill combinations containing two or three antihypertensive agents. Combination therapy provides greater antihypertensive potential, reduced risks for side effects, lower medical cost, increase compliance, and promotes long-term adherence, this latter being the major challenge of drug therapy for hypertension.\u0000\u0000Key words: hypertension, drug therapy.","PeriodicalId":86274,"journal":{"name":"The South Dakota journal of medicine and pharmacy","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84781262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An in vitro scanning electron microscopic study: smear layer removal by chelat activation methods","authors":"Nga Le Thi Thu, Chi Phan Anh","doi":"10.34071/jmp.2022.7.19","DOIUrl":"https://doi.org/10.34071/jmp.2022.7.19","url":null,"abstract":"Background: The process of mechanical root canal preparation creates smear layer. The smear layer can prevent the penetration of intracanal medicaments into dentinal tubules and influence the adaptation of filling materials to canal\u0000walls. The purpose of this study is to compare the smear layer removal ability of root canal irrigation methods with chelat solution. Materials and Methods: 45 extracted human premolar roots were selected and randomly divided into 3 groups (n=15) based on root canal irrigation methods with 17% EDTA solution: (1) Conventional needle irrigation, (2) Ultrasonic activation, (3) Sonic activation. The roots were prepared with Reciproc Blue 25 file and was removed smear layer by 3 different methods of irrigation. The study sample was then sectioned longitudinally with a diamond cutting disc, randomly selecting half of the root. After undergoing sample processing, the half roots were observed and evaluated for the presence of smear layer under a scanning electron microscope with a magnification of 1000 times according to Torabinejad (2003). Results: In cervical, the average smear layer score of the 3 study groups was not statistically significant (p>0.05). In the middle, apical and over the root canal, the average smear layer score of the sonic activation method was lower than that of the other 2 groups. Conclusion: Sonic irrigation is more effective in removing smear layer than conventional needle irrigation and ultrasonic irrigation activation.\u0000Key words: smear layer, ultrasonic, sonic.","PeriodicalId":86274,"journal":{"name":"The South Dakota journal of medicine and pharmacy","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79638809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Periodontal status in male smokers visiting Hue University of Medicine and Pharmacy Hospital","authors":"Thanh Chau Ngoc Phuong, Dan Nguyen Ngoc Tam","doi":"10.34071/jmp.2022.7.13","DOIUrl":"https://doi.org/10.34071/jmp.2022.7.13","url":null,"abstract":"Background: Many clinical studies, which were conducted to evaluate the association between smoking and periodontal diseases, have confirmed the harmful effects of smoking on oral health. Therefore, it is essential to properly assess the periodontal status and smoking habits to improve the effectiveness of interventions and disease prevention. Objective: This study aims to compare the prevalence and severity of periodontal disease in male smokers and male non-smokers visiting Hue University Hospital of Medicine and Pharmacy and to investigate the relationship between smoking and periodontal disease. Methods: A casecontrol study with 220 patients divided into two groups using a questionnaire to survey men aged 18-65 who have been smoking at the Department of Odonto-Stomatology - the Hue University Hospital of Medicine and\u0000Pharmacy. Factors related to smoking behavior and clinical examination of periodontal status were adopted. Results: In the smokers group, the mean gingival index “GI” (0.647 ± 0.316), plaque index “PlI” (2.045 ± 0.447), “PPD” periodontal pocket depth (1.955 ± 0.470mm), clinical adhesion loss “CAL” (1.883 ± 0.771mm), “BOP” bleeding index (4.898 ± 3.117) with 95% confidence interval “CI”. The percentage of patients without periodontitis accounts for the majority compared with the remaining levels of periodontitis with values of smokers 67.27% and 99.36% non-smokers. There is a signficant difference in gingivitis and periodontitis in both study groups with p<0.05. There is a correlation between periodontal indices and smoking indicators such as the number of cigarettes smoked per day, the number of years of smoking, and cumulative exposure\u0000p<0.05. Conclusion: The study shows that the heavier the smoking status, the worse the periodontal condition. However, the more cigarettes smoked, the less gingivitis and bleeding gums. \u0000Key words: Periodontal index, smoking, periodontal disease","PeriodicalId":86274,"journal":{"name":"The South Dakota journal of medicine and pharmacy","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77993844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}