Asian journal of psychiatry最新文献

{"title":"Navigating LMICs challenges through educational and legal reforms to strengthen adolescent mental health in Indonesia","authors":"Zalik Nuryana,&nbsp;Atqo Darmawan Aji,&nbsp;Herdian Herdian","doi":"10.1016/j.ajp.2025.104614","DOIUrl":"10.1016/j.ajp.2025.104614","url":null,"abstract":"<div><div>Adolescent mental health represents a critical yet underserved public health issue, particularly in low- and middle-income countries (LMICs) such as Indonesia. Responding positively to Ramaswamy et al. call for a paradigm shift towards adolescent-centered policy frameworks, this editorial explores the integration of educational strategies and legal frameworks to enhance adolescent mental health interventions. Despite Indonesia's progressive legislation, including the Mental Health Law (No.18/2014) and Juvenile Justice System Law (No.11/2012), substantial gaps remain in youth participation and comprehensive preventive measures. This letter proposes strengthening education-based mental health interventions and restorative justice mechanisms. It further advocates for meaningful adolescent engagement in research and policymaking, positioning education and law as key sectors for navigating LMIC-specific challenges in building resilient adolescent populations.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"111 ","pages":"Article 104614"},"PeriodicalIF":3.8,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144595939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of ICD-11 post-traumatic stress disorder (PTSD) and complex PTSD in the general populations: A systematic review and meta-analysis","authors":"Hong Wang Fung ,&nbsp;Antonia Leousi ,&nbsp;Anson Kai Chun Chau ,&nbsp;Ka Yan Sit ,&nbsp;Cheuk Chi Lam ,&nbsp;Celine Mylx Li ,&nbsp;Chak Hei Ocean Huang ,&nbsp;Cherry Tin Yan Cheung ,&nbsp;Stanley Kam Ki Lam ,&nbsp;Edward K.S. Wang ,&nbsp;Grace Wing Ka Ho","doi":"10.1016/j.ajp.2025.104610","DOIUrl":"10.1016/j.ajp.2025.104610","url":null,"abstract":"<div><div>The ICD-11 has revised the diagnostic criteria for post-traumatic stress disorder (PTSD) and introduced complex PTSD (CPTSD) as a new diagnosis. This study presents the first systematic review and meta-analysis of ICD-11 PTSD and CPTSD prevalence in general population samples. In this pre-registered review (CRD42024579951), we searched the Web of Science, Scopus, and PubMed databases to identify potentially relevant articles. Meta-analyses were conducted among (1) samples from non-war exposed/economically developed countries/regions and (2) samples from war-exposed/less economically developed countries/regions. Out of 835 unique records, 10 eligible studies examining ICD-11 PTSD and CPTSD in representative adult general population samples were included. Most studies were assessed as having a “low risk” of bias across all quality domains. The studies were conducted in Ukraine (3), Germany (2), Republic of Ireland (2), Hong Kong, Israel, Kenya, Nigeria, and Ghana. All studies used the International Trauma Questionnaire (ITQ) to assess ICD-11 PTSD and CPTSD. In the five samples from non-war-exposed/economicallydeveloped countries/regions, the pooled prevalence rates for PTSD and CPTSD were 2 % and 4 %, respectively, based on a total of 7718 participants. In the five samples from war-exposed/less economically developed countries/regions, the pooled prevalence rates for PTSD and CPTSD were 16 % and 15 %, respectively, based on a total of 9870 participants. Given the high prevalence of PTSD and CPTSD, especially in war-exposed/less economically developed countries, there is a pressing need for more effective and scalable interventions to support affected populations. Pooled prevalence rates should be cautiously interpreted due to a limited number of studies.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104610"},"PeriodicalIF":3.8,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144605090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Nardostachys Jatamansi DC as an adjuvant to escitalopram in the treatment of major depressive disorder – A randomized double-blind placebo-controlled study","authors":"VS Jismi,&nbsp;Kishore Kumar Ramakrishna,&nbsp;Urvakhsh Meherwan Mehta ,&nbsp;Shivarama Varambally ,&nbsp;Venkataram Shivakumar ,&nbsp;Talakad N. Sathyaprabha ,&nbsp;Kaviraja Udupa","doi":"10.1016/j.ajp.2025.104611","DOIUrl":"10.1016/j.ajp.2025.104611","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"111 ","pages":"Article 104611"},"PeriodicalIF":3.8,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144595938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of economic crisis on the mental health of children and adolescents: A systematic review","authors":"Rita Feghali ,&nbsp;Charline El-Hachem ,&nbsp;Georges Bakhos ,&nbsp;Myriam Zarzour ,&nbsp;Rami Bou Khalil","doi":"10.1016/j.ajp.2025.104613","DOIUrl":"10.1016/j.ajp.2025.104613","url":null,"abstract":"<div><h3>Introduction</h3><div>Economic crises significantly affect mental health across individuals, families, and communities, with children and adolescents being especially vulnerable. Financial stress, parental distress, and family conflict can disrupt development and increase emotional, behavioural, and cognitive difficulties. This review uses Bronfenbrenner’s ecological systems theory to examine how economic hardship influences youth mental health through interconnected individual, familial, and societal systems.</div></div><div><h3>Methods</h3><div>Following PRISMA guidelines, a systematic search was conducted on PubMed and Google Scholar for studies (2015–2025) addressing economic hardship and mental health in children, adolescents, and parents. Inclusion required original research in English or French, with low or moderate risk of bias assessed using the Newcastle–Ottawa Scale (NOS) and its cross-sectional adaptation (NOS-CSS). Of 7104 records, 66 studies met criteria. Findings were grouped into three domains: mental health outcomes, child development, and the parent–child relationship.</div></div><div><h3>Results</h3><div>Financial hardship was consistently linked to increased rates of depression, anxiety, and substance use, often in a dose-response pattern. Socioeconomic disadvantage worsened access to care and outcomes, especially among the unemployed, less educated, women, and minorities. Youth exposed to economic strain showed higher rates of self-harm and suicide risk. Developmental impact, cognitive, emotional, and physical, was mediated by maternal mental health, parenting, nutrition, and environmental stress. Parental warmth and developmental knowledge emerged as protective factors.</div></div><div><h3>Conclusion</h3><div>Bronfenbrenner’s framework illustrates how economic crises affect child mental health across ecological layers. Coordinated responses addressing parenting, healthcare access, policy, and early-life support are essential to mitigate long-term harm in vulnerable populations.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104613"},"PeriodicalIF":3.8,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144580445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can circadian rhythms of heart rate variability identify major depressive disorder? — A study based on support vector machine analysis","authors":"Bing Li ,&nbsp;Sheng Guo ,&nbsp;Lin Liu ,&nbsp;Hao Xu ,&nbsp;Haitao Chen ,&nbsp;Jiaqi Song ,&nbsp;Yan Chen ,&nbsp;Xia Du ,&nbsp;Shuping Tan","doi":"10.1016/j.ajp.2025.104609","DOIUrl":"10.1016/j.ajp.2025.104609","url":null,"abstract":"<div><h3>Background</h3><div>Major depressive disorder (MDD) is a prevalent and severe psychiatric condition for which objective diagnostic tools are lacking. Heart rate variability (HRV), an index of autonomic nervous system (ANS) function, has shown potential for distinguishing patients with MDD. This study aimed to improve classification performance by leveraging circadian rhythm features derived from multiple HRV indices using a support vector machine (SVM) approach.</div></div><div><h3>Methods</h3><div>Twenty-four-hour electrocardiographic recordings were collected from 116 patients with MDD and 63 healthy controls (HCs). Thirteen HRV indices, spanning the time domain, frequency domain, and nonlinear measures, were extracted, along with five corresponding circadian rhythm features (CRFs) for each index. To reduce feature dimensionality, a recursive feature elimination strategy based on the SVM was applied. The selected CRFs were then used to train the SVM classifier. Separate SVM models were constructed using CRFs derived from linear indices, nonlinear indices, and their combinations. Furthermore, their performance was compared across multiple metrics.</div></div><div><h3>Results</h3><div>The SVM model constructed using CRFs from all HRV indices achieved an accuracy of 97.80 %, sensitivity of 98.01 %, and specificity of 97.60 %. The models based on the CRFs from linear HRV indices outperformed those based on nonlinear indices, whereas the combination of all HRV indices yielded the best overall performance.</div></div><div><h3>Conclusions</h3><div>The results highlight the potential utility of HRV CRFs for objective MDD classification. Moreover, with an equal number of features, the CRFs derived from linear HRV indices proved to be more effective than those derived from nonlinear indices in discriminating patients with MDD.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104609"},"PeriodicalIF":3.8,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144570263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing Thailand’s mental health services to enhance quality of life and recovery outcomes through integrated patient-reported outcome measure","authors":"Peanchanan Leah ,&nbsp;Wachara Riewpaiboon","doi":"10.1016/j.ajp.2025.104608","DOIUrl":"10.1016/j.ajp.2025.104608","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104608"},"PeriodicalIF":3.8,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144557656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex-specific associations between anxiety, depressive symptoms and suicidal ideation in older adults: Undirected and Bayesian network analyses","authors":"Min Li ,&nbsp;Lu Zhang ,&nbsp;Chuchu Li,&nbsp;Haoran Chen,&nbsp;Hailong Shu,&nbsp;Wentao Fang,&nbsp;Fangfang Liu,&nbsp;Linsheng Yang,&nbsp;Gengfu Wang,&nbsp;Puyu Su","doi":"10.1016/j.ajp.2025.104607","DOIUrl":"10.1016/j.ajp.2025.104607","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104607"},"PeriodicalIF":3.8,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144516944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cerebellum and obsessive-compulsive disorder: A narrative review of neuroimaging evidence from MRI studies","authors":"Yuanyuan Yang ,&nbsp;Yu Xia ,&nbsp;Zimo Zhou ,&nbsp;Zhenru Guo ,&nbsp;Lin Tian","doi":"10.1016/j.ajp.2025.104606","DOIUrl":"10.1016/j.ajp.2025.104606","url":null,"abstract":"<div><div>Obsessive-Compulsive Disorder (OCD) is a psychiatric condition characterized by recurrent obsessions (intrusive thoughts) and compulsions (repetitive behaviors), with its neurobiological mechanisms remaining a central focus of research. Since the 1980s, neuroimaging studies have revealed significant structural and functional brain differences between OCD patients and healthy controls. Early research primarily relied on the cortico-striato-thalamo-cortical (CSTC) circuit model to explain OCD pathophysiology. However, magnetic resonance imaging (MRI) studies over the past two decades have identified substantial cerebellar abnormalities closely associated with OCD pathogenesis. This review synthesizes evidence from structural MRI (sMRI), diffusion tensor imaging (DTI), functional MRI (fMRI), and meta-analyses to elucidate the cerebellum's role in OCD. Current findings demonstrate that cerebellar abnormalities in OCD patients not only exist independently but also interact with the basal ganglia and CSTC circuits, thereby refining the traditional CSTC model. These findings point to the cerebellum as a potentially critical node in the broader network underlying OCD symptoms. Future directions include exploration of cerebellar-cortical interactions, particularly at the level of symptom-dimensions and subregional specificity, as well as the development of cerebellum-targeted interventions guided by advanced neuroimaging and computational techniques.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104606"},"PeriodicalIF":3.8,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144549367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"GenAI and psychiatry: Between multimodal promise and ethical perils","authors":"Rio Saputra ,&nbsp;Moh Ramdhan Arif Kaluku ,&nbsp;Hartoto ,&nbsp;Edi Setiawan ,&nbsp;Arizona ,&nbsp;Triana Asih ,&nbsp;Andika Ari Saputra","doi":"10.1016/j.ajp.2025.104605","DOIUrl":"10.1016/j.ajp.2025.104605","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104605"},"PeriodicalIF":3.8,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144502805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breaking the cycle of oxidative stress for better behavioral health in autism spectrum disorder: A scoping review","authors":"Rinvil Renaldi ,&nbsp;Antonio M. Persico ,&nbsp;Tjhin Wiguna ,&nbsp;Andi Jayalangkara Tanra","doi":"10.1016/j.ajp.2025.104575","DOIUrl":"10.1016/j.ajp.2025.104575","url":null,"abstract":"<div><div>Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition marked by socio-communicative and behavioral challenges. ASD is increasingly linked to oxidative stress, which stems from a destructive imbalance state whereby excessive reactive oxygen species (ROS) overwhelm antioxidant defenses. This redox imbalance triggers a cascade of cellular dysfunctions, which in neurons include synaptic inefficiency, altered receptor function, excitotoxicity, and chronic neuroinflammation. All these dysfunctions add an additional burden to the genetic and epigenetic contributions underlying autism pathophysiology in each single individual, ultimately exacerbating ASD core symptoms. Strikingly, children with ASD exhibit diminished antioxidant capacity, correlated with heightened behavioral severity and impaired quality of life. This scoping review explores the intricate relationship between oxidative stress and ASD, evaluating current therapeutic strategies aimed at restoring redox balance while identifying critical research gaps. Interventions such as N-acetylcysteine (NAC), vitamin and mineral supplementation, and dietary antioxidants have shown promise in mitigating oxidative damage and improving social responsiveness. Other strategies, in particular hyperbaric oxygen therapy (HBOT) and cleanroom environments, are highly controversial. Well-designed randomized placebo-controlled trials (RCTs) integrating clinical and psychodiagnostic measures with precision medicine frameworks, are crucial for developing targeted therapies that, restoring redox homeostasis, may optimize neurodevelopmental outcomes. By summarizing current evidence and addressing these gaps, this review underscores the therapeutic potential of oxidative stress correction in improving the quality of life of individuals with ASD.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104575"},"PeriodicalIF":3.8,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144557655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}