Asian journal of psychiatry最新文献

{"title":"Addressing the policy gap between adolescent mental health and school systems in indonesia","authors":"Zalik Nuryana,&nbsp;Herdian","doi":"10.1016/j.ajp.2025.104543","DOIUrl":"10.1016/j.ajp.2025.104543","url":null,"abstract":"<div><div>Adolescent mental health remains an under-addressed priority in national policies across Southeast Asia, including Indonesia. Although mental health legislation and adolescent health programs exist, integration within the school system is limited and inconsistent with international standards. This commentary builds on Mudunna et al.’s regional policy review by highlighting the critical gap in Indonesia’s cross-sectoral coordination between health and education. Drawing on recent national data, we underscore the urgency of school-based mental health interventions in Indonesia, where prevalence rates of anxiety, depression, and suicidal ideation among adolescents are high, yet treatment access remains alarmingly low. We argue that adolescence must be understood not only as a period of psychological vulnerability but also as a transformative stage shaped by biological, social, and legal factors. In the context of LMICs like Indonesia, policy development must consider rights-based, participatory, and culturally appropriate approaches. We call for context-specific frameworks to embed mental health within the national education system as an essential investment in Indonesia’s youth and national development.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"109 ","pages":"Article 104543"},"PeriodicalIF":3.8,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144123674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of response and remission after transcranial magnetic stimulation for major depressive disorder: An international comparative study between Taiwan and Japan","authors":"Che-Sheng Chu ,&nbsp;Cheng-Ta Li ,&nbsp;Chih-Ming Cheng ,&nbsp;Jia-Shyun Jeng ,&nbsp;Chih-Chuan Pan ,&nbsp;Guan-Wei Chen ,&nbsp;Wei-Zhe Liang ,&nbsp;Chun-Hung Chang ,&nbsp;Kyoshiro Fujii ,&nbsp;Ryosuke Kitahata ,&nbsp;Yoshihiro Noda","doi":"10.1016/j.ajp.2025.104541","DOIUrl":"10.1016/j.ajp.2025.104541","url":null,"abstract":"<div><h3>Background</h3><div>This study aimed to identify demographic, clinical, and protocol-related predictors of effectiveness of transcranial magnetic stimulation (TMS) therapy in patients with major depressive disorder (MDD) across Taiwan and Japan.</div></div><div><h3>Methods</h3><div>This retrospective observational study analyzed clinical data collected between September 2023 and August 2024 from patients with MDD treated either repetitive TMS or theta-burst stimulation at two institutes in Taiwan and one in Japan. All patients were assessed using the Hamilton Depression Rating Scale (HAMD) before and after a course of TMS treatment. Variables were assessed for their association with response, remission, and change of HAMD scores from baseline using a multiple logistic and linear regression model.</div></div><div><h3>Results</h3><div>205 patients (131 Taiwanese and 74 Japanese) were included. The Taiwanese population had a significantly higher percentage of females than the Japanese population (71.0 % vs. 42.5 %). Being married (adjusted odd ratios [aOR] = 2.339) and being employed (aOR = 2.048) were more likely to achieve a response, whereas current alcohol use (aOR = 0.332) was less likely to be associated with response. Additionally, patients who were employed (aOR = 2.183) were more likely to achieve remission, whereas those with a longer duration of illness (aOR = 0.938) and current alcohol use (aOR = 0.310) were less likely to reach remission. Furthermore, being female, being married, being employed, and higher baseline HAMD were more likely having greater reductions in HAMD scores.</div></div><div><h3>Conclusions</h3><div>This study suggests the specific predictors when predicting the treatment outcome of TMS for MDD patients in Taiwan and Japan.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"109 ","pages":"Article 104541"},"PeriodicalIF":3.8,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144167874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The depressive symptoms trajectories and risk of all-cause mortality: Findings from the China health and retirement longitudinal study","authors":"Minglan Jiang,&nbsp;Xiao Ren,&nbsp;Wenyang Han,&nbsp;Xiaowei Zheng","doi":"10.1016/j.ajp.2025.104542","DOIUrl":"10.1016/j.ajp.2025.104542","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"109 ","pages":"Article 104542"},"PeriodicalIF":3.8,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144123584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the experiences of academic advisors and psychological counsellors supporting students with mental illnesses: A qualitative study at a public university in Oman","authors":"Abdul Rahman Al Fahdi ,&nbsp;Maryam Alharrasi ,&nbsp;Khalood Al-abri ,&nbsp;Saud Al Nabhani ,&nbsp;Mohammed Al Shajabi ,&nbsp;Sultan Al Hinai","doi":"10.1016/j.ajp.2025.104544","DOIUrl":"10.1016/j.ajp.2025.104544","url":null,"abstract":"<div><h3>Background</h3><div>University students often face challenges that may lead to mental health issues, including depression, anxiety, and psychological distress. Despite the critical role of academic and professional staff in supporting university students with mental health concerns, limited research has examined their experiences in providing this support.</div></div><div><h3>Aims</h3><div>This study aimed to explore experiences and challenges faced by psychological counsellors and academic advisors in assisting university students with mental health issues.</div></div><div><h3>Methods</h3><div>A qualitative descriptive research design was employed. Purposive sampling was conducted to recruit 14 participants from public university in Oman, including nine academic advisors and five psychological counsellors. Data were collected through semi-structured interviews, transcribed verbatim, and thematically analysed using inductive and deductive approaches.</div></div><div><h3>Results</h3><div>Two main themes emerged: (1) <em>Identifying mental health issues in students</em>, encompassing subthemes of poor academic performance and personal or family issues; and (2) <em>Access to support systems</em>, with subthemes including pathways of support, limited time for interaction, barriers to open communication, and systemic challenges.</div></div><div><h3>Conclusions</h3><div>The findings emphasize the need for universities to develop clear policies and crisis management protocols for supporting students with mental health challenges. Enhanced training on mental health issues and improved support mechanisms are also recommended.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"109 ","pages":"Article 104544"},"PeriodicalIF":3.8,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144135153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Truth or myth of minimum effective dose for patients with remitted psychosis: Implications from a guided dose reduction trial","authors":"Ko Yen ,&nbsp;Ming H. Hsieh ,&nbsp;Yi-Ling Chien ,&nbsp;Chih-Min Liu ,&nbsp;Yi-Ting Lin ,&nbsp;Tzung-Jeng Hwang ,&nbsp;Chun-I. Liu ,&nbsp;Chen-Chung Liu","doi":"10.1016/j.ajp.2025.104534","DOIUrl":"10.1016/j.ajp.2025.104534","url":null,"abstract":"<div><h3>Objective</h3><div>Optimizing antipsychotic dosage is crucial for patients to resume functioning without increased risk of relapse. The reported antipsychotic minimum effective dose (MED) for treatment of either acute phase or stable patients is a chlorpromazine equivalent (CPZE) dose of 200 mg/d. A cohort of remitted patients undergoing prospective dose reduction were evaluated to determine if a dose less than the designated MED could still provide adequate prophylactic effects.</div></div><div><h3>Methods</h3><div>Ninety-six individuals with schizophrenia-related psychotic disorders whose symptoms were stable with their current medication were eligible for a 2-year dose tapering trial. Divided into two groups according to antipsychotic doses (CPZE &gt; 200 vs. CPZE ≤ 200 mg/d), we evaluated if there were differences in clinical severities, personal social performance, quality of life, medication satisfaction, and employment status between baseline and the end of 2-year follow-up.</div></div><div><h3>Results</h3><div>At baseline, 59 participants received CPZE ≤ 200 mg/d and 37 participants received CPZE &gt; 200 mg/d. At the 2-year follow-up, 42 patients had successfully reduced their doses. Among subgroups, 13 participants whose doses were reduced from &gt; 200 mg/d to ≤ 200 mg/d had clinical outcomes comparable to their baseline levels; while 45 patients who received ≤ 200 mg/d throughout the 2 years showed significantly better outcomes, such improvements were mainly contributed by 25 of them further reducing antipsychotics at such a low dose level.</div></div><div><h3>Conclusion</h3><div>Maintenance dose CPZE ≤ 200 mg/d was common in this small sample-sized cohort. Careful dose tapering allowed some patients to reduce antipsychotics further with no increased risk of relapse and were able to improve their functioning.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"109 ","pages":"Article 104534"},"PeriodicalIF":3.8,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144099836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retinal macular morphology and cognitive functions in unmedicated first-episode psychosis patients","authors":"Neethu Kanjingat Nandan ,&nbsp;Sai Krishna Tikka ,&nbsp;Vijaya Sahu ,&nbsp;Shrayasi Das ,&nbsp;Rana Prathap Padappayil ,&nbsp;Puneet Kumar Soni ,&nbsp;Avinash Shukla ,&nbsp;Lokesh Kumar Singh","doi":"10.1016/j.ajp.2025.104529","DOIUrl":"10.1016/j.ajp.2025.104529","url":null,"abstract":"<div><h3>Background</h3><div>This study investigates retinal macular abnormalities and neurocognitive function, including facial emotion recognition, in individuals with unmedicated First-Episode Psychosis (FEP). The primary aim is to compare retinal morphology in FEP patients and healthy controls and examine correlations with cognitive performance.</div></div><div><h3>Method</h3><div>Thirty-two FEP patients (aged 18–45) and 30 healthy controls underwent psychiatric assessment and retinal examination using the Spectral Domain - Optical Coherence Tomography (SD-OCT), with a focus on macula. Facial emotion recognition was evaluated using the Mandal emotion recognition test for four emotions (Sad, Anger, Happy, Fear). Visual memory and executive function were assessed using the Rey-Osterrieth Complex Figure Test and the Trail Making Test, respectively. Statistical analyses included t-test, correlation analysis, and linear discriminant function analysis.</div></div><div><h3>Results</h3><div>FEP patients showed significant macular abnormalities, with reduced thickness in multiple quadrants. Facial emotion recognition scores were notably lower among patients for all emotions tested. Patients also showed visual memory deficits. Across the three measures there were significant correlations. Discriminant function analysis indicated that a combination of emotion recognition scores and inner nasal quadrant macular thickness of left eye could effectively differentiate patients from healthy controls with high accuracy (85.5 %).</div></div><div><h3>Conclusion</h3><div>Our study demonstrates significant macular abnormalities, impaired facial emotion recognition, and visual memory deficits in patients with unmedicated FEP. These findings suggest potential of retinal abnormalities as biomarkers for psychosis. Future research with larger sample sizes could further establish retinal changes and facial emotion recognition as potential biomarkers.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"109 ","pages":"Article 104529"},"PeriodicalIF":3.8,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144138558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Machine learning prediction prior to onset of mild cognitive impairment using T1-weighted magnetic resonance imaging radiomic of the hippocampus","authors":"Shiqi Zhan ,&nbsp;Jiawei Wang ,&nbsp;Jie Dong ,&nbsp;Xinru Ji ,&nbsp;Li Huang ,&nbsp;Qingqing Zhang ,&nbsp;Daixuan Xu ,&nbsp;Lixin Peng ,&nbsp;Xiuxiu Wang ,&nbsp;Yusi Zhang ,&nbsp;Shengxiang Liang ,&nbsp;Lidian Chen ,&nbsp;for the Alzheimer’s Disease Neuroimaging Initiative","doi":"10.1016/j.ajp.2025.104532","DOIUrl":"10.1016/j.ajp.2025.104532","url":null,"abstract":"<div><h3>Background</h3><div>Early identification of individuals who progress from normal cognition (NC) to mild cognitive impairment (MCI) may help prevent cognitive decline. We aimed to build predictive models using radiomic features of the bilateral hippocampus in combination with scores from neuropsychological assessments.</div></div><div><h3>Methods</h3><div>We utilized the Alzheimer's Disease Neuroimaging Initiative (ADNI) database to study 175 NC individuals, identifying 50 who progressed to MCI within seven years. Employing the Least Absolute Shrinkage and Selection Operator (LASSO) on T1-weighted images, we extracted and refined hippocampal features. Classification models, including Logistic Regression (LR), Support Vector Machine (SVM), Random Forest (RF), and light gradient boosters (LightGBM), were built based on significant neuropsychological scores. Model validation was conducted using 5-fold cross-validation, and hyperparameters were optimized with Scikit-learn, using an 80:20 data split for training and testing.</div></div><div><h3>Results</h3><div>We found that the LightGBM model achieved an area under the receiver operating characteristic (ROC) curve (AUC) value of 0.89 and an accuracy of 0.79 in the training set, and an AUC value of 0.80 and an accuracy of 0.74 in the test set.</div></div><div><h3>Conclusion</h3><div>The study identified that T1-weighted magnetic resonance imaging radiomic of the hippocampus would be used to predict the progression to MCI at the normal cognitive stage, which might provide a new insight into clinical research.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"108 ","pages":"Article 104532"},"PeriodicalIF":3.8,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144072128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multidimensional diagnostic features and intervention pathways for youth mental disorders in China’s involution society","authors":"Yuan Tao ,&nbsp;Yanping Lu ,&nbsp;Wei Shi ,&nbsp;Guangzhe Frank Yuan","doi":"10.1016/j.ajp.2025.104531","DOIUrl":"10.1016/j.ajp.2025.104531","url":null,"abstract":"<div><div>This short communication examines the complex relationship between China’s intensifying social involution and rising mental disorders among youth. We analyze the multidimensional diagnostic challenges specific to this cultural context and propose evidence-based intervention pathways. Key findings highlight the necessity of culturally-sensitive diagnostic approaches that account for China’s unique socioeconomic pressures, the manifestation of “involution anxiety” as a culturally-bound syndrome, and the effectiveness of integrated intervention frameworks combining traditional Chinese approaches with contemporary psychotherapeutic techniques. This work contributes to the growing body of transcultural psychiatry literature and provides practical guidance for mental health professionals working with Chinese youth populations.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"108 ","pages":"Article 104531"},"PeriodicalIF":3.8,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144072129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial intelligence in autism spectrum disorder: A path to early detection and improved outcomes","authors":"Prakriti Pokhrel ,&nbsp;Surbhi Joshi ,&nbsp;Laraib Fatima","doi":"10.1016/j.ajp.2025.104530","DOIUrl":"10.1016/j.ajp.2025.104530","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"109 ","pages":"Article 104530"},"PeriodicalIF":3.8,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144099837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors contributing to treatment non-compliance in a large sample of psychiatric patients in Turkey","authors":"Abdulbari Bener ,&nbsp;Mustafa Hakan Saldı ,&nbsp;Dinesh Bhugra ,&nbsp;Antonio Ventriglio","doi":"10.1016/j.ajp.2025.104528","DOIUrl":"10.1016/j.ajp.2025.104528","url":null,"abstract":"<div><h3>Objective</h3><div>This study aims to investigate the determinants of treatment non-compliance among psychiatric patients by exploring related factors.</div></div><div><h3>Methods</h3><div>This is a cross-sectional study including patients hospitalized for psychiatric disorders and aged between 25 and 70 years in Istanbul, Turkey. 1648 patients were approached and 1310 (79.5 %) agreed to participate. A set of sociodemographic and clinical variables were collected as well as the Turkish Version of the 9-item Patient-Doctor Relationship Questionnaire (PDRQ-9) was administered. Statistical analyses included t-tests, chi-square tests, factor analysis, Confirmatory Factor Analysis, and computation of the Lorenz curve and Gini index.</div></div><div><h3>Results</h3><div>Of 1310 patients, 761 (58.1 %) were compliant with treatments while 549 (41.9 %) were considered as non-compliant. Patients aged above 60 years were significantly less represented in the compliant group of patients (p = 0.008). Non-compliant patients were more like to be obese (p = 0.046), cigarette smokers (p = 0.019), nargileh-hookah users (p = 0.037), and perform less physical exercise (p = 0.044). Patients diagnosed with schizophrenia (p = 0.034), bipolar disorder (p = 0.016), depression (p = 0.008), obsessive-compulsive disorder (p = 0.015) and dementia/Alzheimer’s disease (p = 0.003) were more likely to be compliant with treatments whereas patients affected by stress or post-traumatic stress disorder were significantly less complaint (p = 0.015 and p = 0.006, respectively). The main factors contributing to non-compliance included lack of social supervision and family support (p &lt; 0.001), not regular attendance of the mental health services (p = 0.016), lack of insight towards treatments (p = 0.0124), lack of satisfaction with the doctor (p = 0.021), lack of education regarding medications side effects (p &lt; 0.001), and poor perceived improvement with treatment (p = 0.005). Concurrently, the exploratory and confirmatory factor analyses confirmed validity and psychometric characteristics of the Turkish version of the 9-item Patient-Doctor Relationship Questionnaire (PDRQ-9).</div></div><div><h3>Conclusion</h3><div>This study reported a high prevalence rate of non-compliance among psychiatric patients. An empathetic patient-doctor approach, shared decision making as well as socially supportive and psychoeducational interventions are potentially useful for improving patients’ attitudes toward treatments and their compliance.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"109 ","pages":"Article 104528"},"PeriodicalIF":3.8,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144099835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}