Asian journal of psychiatry最新文献

{"title":"Long-term vocational outcomes in low- and high-fidelity supported employment programs: A multi-site study with 6 years of follow-up","authors":"Sosei Yamaguchi ,&nbsp;Takayuki Kawaguchi ,&nbsp;Mai Iwanaga ,&nbsp;Kaori Usui ,&nbsp;Momoka Igarashi ,&nbsp;Takuma Shiozawa ,&nbsp;Junko Koike ,&nbsp;Sayaka Sato ,&nbsp;Chiyo Fujii","doi":"10.1016/j.ajp.2025.104572","DOIUrl":"10.1016/j.ajp.2025.104572","url":null,"abstract":"<div><div>Although the effectiveness of the Individual Placement and Support (IPS) model of supported employment has been recognized, the long-term vocational outcomes associated with variations in the structural quality of IPS programs remain unclear. This study investigated the impact of IPS program fidelity on long-term vocational outcomes over 6 years in Japan. The eligible study participants were 202 individuals in 16 IPS programs who were initially enrolled in a 2-year follow-up study and monitored for an additional 4 years. The fidelity of the participating IPS programs was measured using the Japanese version of the individualized Supported Employment Fidelity Scale. Seven and eight programs were classified as low and high fidelity, respectively. The analysis included 123 participants in 15 programs (follow-up rate: 61 %). During the follow-up period, the high-fidelity group had significantly higher employment rates (54.0 % vs. 88.3 %; adjusted odds ratio: 6.5, 95 % confidence interval [CI]: 1.3–31.2, p = 0.020), longer work tenures (adjusted mean difference [aMD]: 14.4 months, 95 %CI: 2.3–26.5, p = 0.020), and higher earnings (shown in USD) (aMD: 10,573.0, 95 %CI: 2119.3–19,026.7, p = 0.014). While the employment rates were significantly higher in the high-fidelity group than in the low-fidelity group until year 4, this difference diminished after year 5. Thus, high-fidelity IPS programs can achieve sustained vocational benefits, and ongoing fidelity reviews and maintenance appear essential for optimizing long-term employment outcomes. The findings also suggest practical considerations regarding the timing of IPS service termination and strategies for long-term engagement with service users who have left their jobs in real-world contexts.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104572"},"PeriodicalIF":3.8,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144279620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reframing peer mental health support: Communalism as a cultural resource for building community resilience in Southeast Asian universities","authors":"Ashari Mahfud ,&nbsp;Anisatul Latifah,&nbsp;Rudi Haryadi,&nbsp;Indah Lestari,&nbsp;Urotul Aliyah,&nbsp;M. Harwansyah Putra Sinaga","doi":"10.1016/j.ajp.2025.104574","DOIUrl":"10.1016/j.ajp.2025.104574","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104574"},"PeriodicalIF":3.8,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144264032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of high-definition transcranial direct current stimulation (HD-tDCS) on resting brain functional connectivity in schizophrenia patients with persistent auditory verbal hallucinations","authors":"Rujuta Parlikar,&nbsp;Harleen Chhabra,&nbsp;Sowmya Selvaraj,&nbsp;Venkataram Shivakumar,&nbsp;Vanteemar S. Sreeraj,&nbsp;Dinakaran Damodharan,&nbsp;Satish Suhas,&nbsp;Janardhanan C. Narayanaswamy,&nbsp;Naren P. Rao,&nbsp;Ganesan Venkatasubramanian","doi":"10.1016/j.ajp.2025.104571","DOIUrl":"10.1016/j.ajp.2025.104571","url":null,"abstract":"<div><div>High-definition transcranial Direct Current Stimulation (HD-tDCS) is an emerging neuromodulation technique for treating auditory verbal hallucinations (AVH) in schizophrenia (SZ) that do not respond adequately to psychotropic treatments. We are unaware of any functional Magnetic Resonance Imaging (fMRI) study examining the neural effect of HD-tDCS on AVH in SZ. In this study, we examined the effect of MRI-neuronavigated HD-tDCS on functional brain connectivity using fMRI in SZ patients (N = 34) with persistent AVH. HD-tDCS was delivered in a double-blind, randomized, parallel-arm, sham-controlled design (5 days of twice daily, 20-minute sessions). The resting-state fMRI data was acquired using a 3 T scanner. Active HD-tDCS treatment, in comparison to the sham, resulted in significant changes in the resting-state functional connectivity involving Heschl’s gyrus, temporoparietal junction, caudate nucleus, precuneus, lateral occipital cortex, and hippocampus. Our study shows that HD-tDCS causes brain connectivity changes in regions implicated in AVH pathogenesis in SZ.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104571"},"PeriodicalIF":3.8,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144279621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility and preliminary findings of the digital self-management program for people with schizophrenia in Indonesia","authors":"Sri Padma Sari ,&nbsp;Faith Martin ,&nbsp;Deborah Lycett ,&nbsp;Andy Turner","doi":"10.1016/j.ajp.2025.104568","DOIUrl":"10.1016/j.ajp.2025.104568","url":null,"abstract":"<div><h3>Background</h3><div>Individuals with schizophrenia often experience self-management challenges due to the symptoms and mental health problems that impact the recovery process. Currently, digital interventions have shown potential effectiveness for people with schizophrenia in low- and middle-income countries. However, no such studies have been undertaken in Indonesia. We developed HOPE4Schizophrenia, a 6-week co-created digital self-management program. This study aimed to examine the feasibility of HOPE4Schizophrenia for people with schizophrenia<strong>.</strong></div></div><div><h3>Methods</h3><div>A total of 35 participants enrolled in the intervention. The primary outcomes were to investigate recruitment rates, adherence rates, engagement rates, progression criteria, and participants’ satisfaction with the intervention. The secondary outcomes measured hope, recovery, and mental well-being at pre-, post-, and 3-month follow-up.</div></div><div><h3>Results</h3><div>The results showed that the recruitment, adherence, and engagement rates were high (50.7 %, 79 %, and 85 %, respectively). All the predetermined progression criteria were met. Most participants (90 %) reported that they found the course useful. There was a significant difference in recovery between pre-course and post-course and follow-up (F(2, 48) = 4.997, p = 0.011). There were no significant differences in hope and mental well-being at the three time points.</div></div><div><h3>Conclusions</h3><div>All progression criteria for a definitive trial were met, as supported by high recruitment, adherence, and engagement rates. While this study was not powered to detect effectiveness, preliminary findings indicated that HOPE4schizophrenia has the potential to support recovery in individuals with schizophrenia. This study presents a novel and promising finding for HOPE4schizophrenia. A future trial is needed to test the clinical effectiveness of this intervention.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104568"},"PeriodicalIF":3.8,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144239902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An urgent call for safe reporting of suicide in Vietnam","authors":"Josh Nguyen","doi":"10.1016/j.ajp.2025.104569","DOIUrl":"10.1016/j.ajp.2025.104569","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"109 ","pages":"Article 104569"},"PeriodicalIF":3.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144212107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Toxic echo chambers: The manosphere, adolescent liminality, and youth violence","authors":"Jayaprakash Rajendran","doi":"10.1016/j.ajp.2025.104546","DOIUrl":"10.1016/j.ajp.2025.104546","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"109 ","pages":"Article 104546"},"PeriodicalIF":3.8,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144212106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early detection of neurodevelopmental disorders in children with delayed milestones: Navigating between overlapping trajectories and the limits of a single-diagnosis categorical approach (A Preliminary Study for the CONDOR Cohort)","authors":"Hugo Zoppé ,&nbsp;Louise Trocmet ,&nbsp;Aude Rambault ,&nbsp;Yannis Abtroun ,&nbsp;Diane Defresne ,&nbsp;Marie Ansoborlo ,&nbsp;Margaux Hazard ,&nbsp;Frédérique Bonnet-Brilhault","doi":"10.1016/j.ajp.2025.104561","DOIUrl":"10.1016/j.ajp.2025.104561","url":null,"abstract":"<div><h3>Context</h3><div>Neurodevelopmental disorders are characterized by motor, language, cognitive, or socio-emotional delays and/or deficits in affected children. However, a categorical view of these disorders leads to a limited understanding of the challenges they pose.</div></div><div><h3>Methods</h3><div>Among 184 children aged 1–7 years, referred due to concerns about their development and who subsequently received a primary diagnosis of ADHD, ASD, IDD, LD, or DCD following a care pathway in a child psychiatry service, we assessed delays in gross and fine motor skills, language, and socio-emotional development. Delays were assessed based on the child’s age using developmental milestones from the American Academy of Pediatrics. Adjustments were made for age, sex, and medical history.</div></div><div><h3>Results</h3><div>Our findings indicate that children with NDDs exhibit functional overlaps. The number of fine motor delays was comparable among children with ASD, DCD, and IDD. Similarly, language delays did not differ significantly among those with ASD, LD, and IDD. Children with ADHD did not exhibit more fine motor difficulties than those with other diagnoses. Children with IDD were among the most significantly affected across all four evaluated domains.</div></div><div><h3>Discussion</h3><div>These results highlight the intertwined nature of these domains in early neurodevelopment, even though the lack of data on comorbidities significantly limits our conclusions. Nevertheless, it emphasizes the importance of adopting a functional approach to enhance early detection. This also calls into question the relevance of the categorical DSM approach in both clinical practice and research, emphasizing the need to establish a functional classification of delays and deficits.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"109 ","pages":"Article 104561"},"PeriodicalIF":3.8,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144194744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"China’s 2025–2027 mental health service initiative: A model for global mental health equity and innovation","authors":"Yiyang Liu,&nbsp;Shanshan Liu,&nbsp;Hongguang Chen","doi":"10.1016/j.ajp.2025.104560","DOIUrl":"10.1016/j.ajp.2025.104560","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104560"},"PeriodicalIF":3.8,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144229848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Convulsive status epilepticus following electroconvulsive therapy: A rare but critical complication – A case report","authors":"Swapnajeet Sahoo ,&nbsp;Nidhi Yadav,&nbsp;Rajlaxmi,&nbsp;Yash Saini,&nbsp;Subho Chakrabarti,&nbsp;Sandeep Grover","doi":"10.1016/j.ajp.2025.104567","DOIUrl":"10.1016/j.ajp.2025.104567","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"109 ","pages":"Article 104567"},"PeriodicalIF":3.8,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144194461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Resting-state functional connectivity of neural circuits associated with primary and secondary rewards linked to positive and negative symptoms of first-episode schizophrenia","authors":"Jing Shi ,&nbsp;Huihui Yang ,&nbsp;Hua Guo ,&nbsp;Sijia Liu ,&nbsp;Fengmei Fan ,&nbsp;Hongzhen Fan ,&nbsp;Huimei An ,&nbsp;Shuping Tan ,&nbsp;Fude Yang ,&nbsp;Zhiren Wang","doi":"10.1016/j.ajp.2025.104477","DOIUrl":"10.1016/j.ajp.2025.104477","url":null,"abstract":"<div><h3>Background</h3><div>Schizophrenia may be diagnosed based on the presence of positive and negative symptoms. However, the underlying pathophysiology of these positive and negative symptoms remains poorly understood. In this study, we used resting-state functional connectivity (rsFC) to evaluate the integrity of neural circuits associated with primary and secondary rewards in first-episode schizophrenia (FES) and their relationship with positive and negative symptoms to better understand the physiological and pathological mechanisms of positive or negative symptoms.</div></div><div><h3>Methods</h3><div>A total of 109 patients with FES (34 with primary negative symptoms [PNS] and 75 with primary positive symptoms [PPS]) and 42 healthy controls (HCs) underwent resting-state functional magnetic resonance imaging. The rsFC was assessed using a region-of-interest-based approach.</div></div><div><h3>Results</h3><div>Patients with FES exhibited reduced rsFC in neural circuits associated with both primary and secondary rewards, with greater reductions in those with PNS than in those with PPS. While PPS was associated with weaker rsFC than HCs, it did not correlate with symptom severity. Conversely, greater rsFC reductions were linked to more severe negative symptoms.</div></div><div><h3>Conclusions</h3><div>These findings suggest abnormal rsFC in neural circuits associated with both primary and secondary rewards in FES, with more pronounced impairments in PNS.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104477"},"PeriodicalIF":3.8,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144231946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}