{"title":"Suicide rates in China: What will be the next?","authors":"Jie Zhang","doi":"10.1016/j.ajp.2025.104603","DOIUrl":"10.1016/j.ajp.2025.104603","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104603"},"PeriodicalIF":3.8,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144480895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giulio Corrivetti , Francesco Monaco , Annarita Vignapiano , Alessandra Marenna , Ernesta Panarello , Benedetta Di Gruttola , Stefania Landi , Raffaele Malvone , Corrado Vecchi , Stefano Leo , Pietro Carmellini , Luca Steardo Jr , Marco Solmi , Riccardo Panella , Alessio Fasano
{"title":"Precision medicine for depression: Improving treatment response and remission","authors":"Giulio Corrivetti , Francesco Monaco , Annarita Vignapiano , Alessandra Marenna , Ernesta Panarello , Benedetta Di Gruttola , Stefania Landi , Raffaele Malvone , Corrado Vecchi , Stefano Leo , Pietro Carmellini , Luca Steardo Jr , Marco Solmi , Riccardo Panella , Alessio Fasano","doi":"10.1016/j.ajp.2025.104585","DOIUrl":"10.1016/j.ajp.2025.104585","url":null,"abstract":"<div><div>This review synthesises current knowledge to improve understanding of the pathophysiology of major depressive disorder (MDD) and optimise diagnostic, therapeutic and prognostic approaches. It examines the interplay between genetic, epigenetic, inflammatory, neurotransmitter and gut microbiome factors, together with environmental stressors and different clinical symptom presentations, in shaping MDD presentation and treatment response. Studies have revealed potential biomarkers predictive of treatment response, allowing differentiation of MDD subtypes and facilitating remission monitoring. While studies have identified potential biomarkers predictive of treatment response and enabling MDD subtype differentiation, significant challenges remain in achieving fully optimized therapeutic efficacy and widespread remission. A holistic, data-driven approach is key to addressing the complex aetiology of MDD, ultimately improving outcomes for patients and reducing the substantial burden of this prevalent disorder.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104585"},"PeriodicalIF":3.8,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144549366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dynamics of mental health policy in Indonesia","authors":"Suci Megawati, Rafialdo Arifian","doi":"10.1016/j.ajp.2025.104600","DOIUrl":"10.1016/j.ajp.2025.104600","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104600"},"PeriodicalIF":3.8,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144471286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jun Huang , Xiao-Qian Peng , Ri-Hui Liu , Shi-Bin Wang , Wen-Wang Rao
{"title":"The twelve-month prevalence of mental disorders among Teochew adults in the Teoswa region of China: An epidemiological study","authors":"Jun Huang , Xiao-Qian Peng , Ri-Hui Liu , Shi-Bin Wang , Wen-Wang Rao","doi":"10.1016/j.ajp.2025.104592","DOIUrl":"10.1016/j.ajp.2025.104592","url":null,"abstract":"<div><div>The Teoswa region is a distinctive cultural area in the eastern coastal Guangdong Province, China. The trend of rapidly increasing burden of mental disorders in the Teoswa region highlights the necessity to grasp the latest prevalence of mental disorders among Teochew adults. A multistage stratified cluster random sampling method was implemented in the Teoswa region between September and December 2021. A two-phase diagnostic procedure was used: multiscale screening and the Mini International Neuropsychiatric Interviews (MINI) diagnosis. This study found that the 12-month prevalence of mental disorders was (7.05 %, 95 %CI: 5.91 %-8.38 %). Sleep disorders showed the highest prevalence rate (4.37 %, 95 %CI: 3.49 %-5.47 %), followed by anxiety disorders (3.19 %, 95 %CI: 2.43 %-4.18 %), mood disorders (1.81 %, 95 %CI: 1.27 %-2.57 %), Alzheimer's disease (0.34 %, 95 %CI: 0.16 %-0.72 %), schizophrenia (0.23 %, 95 %CI: 0.07 %-0.72 %), posttraumatic stress disorder (0.12 %, 95 %CI: 0.03 %-0.47 %). Facing the non-negligible epidemic of mental disorders in the Teoswa region, policymakers should prioritize evidence-based prevention and intervention measures to address this public health challenge.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104592"},"PeriodicalIF":3.8,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144523790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rapid and sustained remission in refractory OCD using accelerated rTMS targeting the SMA: A case report","authors":"Niyati Narang, Nidhi Kulhar, Vishal Sinha","doi":"10.1016/j.ajp.2025.104601","DOIUrl":"10.1016/j.ajp.2025.104601","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104601"},"PeriodicalIF":3.8,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144480896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Enhancing student mental health through Mindfulness-based Stress Reduction (MBSR) toward curricular and cultural integration","authors":"Zalik Nuryana, Xiaoyu Ni, Herdian, Shiqi Lu, Wenbin Xu, Suyadi","doi":"10.1016/j.ajp.2025.104598","DOIUrl":"10.1016/j.ajp.2025.104598","url":null,"abstract":"<div><div>Student mental health is receiving increasing attention due to escalating academic, social, and emotional pressures, particularly in Asian educational contexts. Mindfulness-Based Stress Reduction (MBSR), has shown consistent effectiveness in alleviating anxiety, enhancing emotional regulation, and fostering psychological resilience among students. While the systematic review by Hue et al. affirms these general benefits, it does not explore critical areas for future research. This article highlights five underexplored dimensions: the structural integration of MBSR into formal curricula, the neuropsychological mechanisms underpinning its educational impact, the digital and geographic accessibility challenges in Asian contexts, the absence of culturally adapted hybrid delivery models, and the lack of comparative analysis between MBSR and indigenous contemplative practices such as dhikr, vipassana, zazen, and samatha. Addressing these gaps is essential to develop culturally relevant, pedagogically sound, and scalable MBSR interventions for educational systems in Asia.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104598"},"PeriodicalIF":3.8,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144471288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Warut Aunjitsakul , Kanthee Anantapong , Nisan Werachattawan , Kreuwan Jongbovonwiwat , Rasmon Kalayasiri , Daruj Aniwattanapong , Poom Chompoosri , Andre Tay Teck Sng , Samuel Cheng Eng Teck , Sanjiv Nair Sasidharan , David Choon Liang Teo , Petrin Redayani Lukman , Sylvia Detri Elvira , Alfi Fajar Almasyhur , Nik Ruzyanei Nik Jaafar , Farah Nabila , Jiann Lin Loo , Nuur Asyikin binti Mohd Shukor , Eric Bui , Vu Tuong Vi , César A. Alfonso
{"title":"Perspectives on psychotherapy in Southeast Asia: Insights from psychiatrists and trainees (Part I: Attitudes, current practices and training preferences)","authors":"Warut Aunjitsakul , Kanthee Anantapong , Nisan Werachattawan , Kreuwan Jongbovonwiwat , Rasmon Kalayasiri , Daruj Aniwattanapong , Poom Chompoosri , Andre Tay Teck Sng , Samuel Cheng Eng Teck , Sanjiv Nair Sasidharan , David Choon Liang Teo , Petrin Redayani Lukman , Sylvia Detri Elvira , Alfi Fajar Almasyhur , Nik Ruzyanei Nik Jaafar , Farah Nabila , Jiann Lin Loo , Nuur Asyikin binti Mohd Shukor , Eric Bui , Vu Tuong Vi , César A. Alfonso","doi":"10.1016/j.ajp.2025.104597","DOIUrl":"10.1016/j.ajp.2025.104597","url":null,"abstract":"<div><h3>Introduction</h3><div>Psychotherapy is an evidence-based treatment for mental disorders. Despite its global development, neuroscientific advances, and measurable efficacy, attitudes toward psychotherapy in Southeast Asia (SEA) remain underexplored, particularly among psychiatrists and psychiatric trainees.</div></div><div><h3>Objectives</h3><div>This study aimed to assess attitudes toward psychotherapy, its current use in clinical practice, and stated preferences for future training among psychiatrists and trainees in SEA.</div></div><div><h3>Methods</h3><div>A cross-sectional online survey was conducted across Indonesia, Malaysia, Singapore, Thailand, and Vietnam. The questionnaire explored perspectives on psychotherapy and its integration into practice. Data were analyzed descriptively and comparatively.</div></div><div><h3>Results</h3><div>Of 253 respondents, 149 (58.9 %) were psychiatrists and 104 (41.1 %) were psychiatric trainees. Both groups exhibited positive attitudes toward psychotherapy, recognizing its professional value, clinical efficacy, and integration with pharmacotherapy. Combination therapy was frequently used; pharmacotherapy dominated for severe disorders, psychotherapy for adjustment and personality disorders, and ECT primarily for schizophrenia, depression, and bipolar disorder. Commonly used therapies include cognitive behavioral therapy, supportive psychotherapy, and mindfulness-based approaches. Psychiatrists favored expanding the number of psychotherapists, while trainees expressed stronger interest in advanced psychodynamic techniques and psychoanalysis. Both groups advocated for additional training in evidence-based psychotherapies and foundational clinical skills.</div></div><div><h3>Conclusion</h3><div>Psychiatrists and trainees in SEA value psychotherapy and its relevance to both clinical practice and everyday life. There is a general preference for integrating psychotherapy with psychopharmacological treatment. Future efforts should focus on enhancing psychotherapy training, addressing cultural adaptations, and overcoming systemic challenges to improve access and efficacy of interventions in SEA.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104597"},"PeriodicalIF":3.8,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144365139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence of exposure to Adverse Childhood Experiences in the past and current Socio Emotional Behavioral Difficulties among institutionalised children","authors":"Ismail Zabiulla Rifai , Mahalakshmy Thulasingam , Shivanand Kattimani , KC Premarajan","doi":"10.1016/j.ajp.2025.104595","DOIUrl":"10.1016/j.ajp.2025.104595","url":null,"abstract":"<div><h3>Background</h3><div>Adverse Childhood Experiences (ACEs) such as abuse, neglect, and family disruptions are common among orphaned children and impact their socio-emotional development. Understanding these experiences is essential to tailor effective interventions.</div></div><div><h3>Objective</h3><div>To estimate the prevalence of significant ACEs and socio-emotional behavioural difficulties (SEBD) among children (5–18 years) in Child Care Institutions (CCIs) in Puducherry, India, and assess the association between them.</div></div><div><h3>Methods</h3><div>A cross-sectional analytical study was conducted across nine CCIs in Puducherry between April 2022 and October 2023, involving 195 children. Multistage sampling was used. ACEs before admission to CCIs were assessed through caretaker interviews and child records. Current SEBD was measured using validated tools from the caretakers' perspective. Proportions with 95 % CI were calculated. Spearman correlation and log-binomial regression were used to assess associations.</div></div><div><h3>Results</h3><div>Among 195 children, 66.6 % were girls. Severe ACE exposure (≥4 ACEs) was found in 42.1 % (95 % CI: 35.2–49.1), with emotional neglect (60 %) being most common. Girls experienced more physical neglect (43.8 %) than boys (10.7 %). SEBD was present in 47.2 % (95 % CI: 40.2–54.2), mainly in the conduct domain (52.3 %). Higher scores on ACEs scale significantly correlated with conduct problems (rho = 0.2, p < 0.01). Children with SEBD had 1.82 times higher risk of having experienced ≥ 4 ACEs (p < 0.04).</div></div><div><h3>Conclusion</h3><div>The study identified the nature and burden of adversities and behavioural issues. Strengthening staff capacity for early identification and linking children to appropriate support services is essential.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104595"},"PeriodicalIF":3.8,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144502804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}