Asian journal of psychiatry最新文献

{"title":"Intravenous non-medical mephentermine use among young men: A consecutive case series from a tertiary addiction treatment facility in India","authors":"Vinit Patel ,&nbsp;Harsha ,&nbsp;Arun Kumar ,&nbsp;Rizwana Quraishi ,&nbsp;Ravindra Rao","doi":"10.1016/j.ajp.2025.104525","DOIUrl":"10.1016/j.ajp.2025.104525","url":null,"abstract":"<div><h3>Introduction</h3><div>Mephentermine, a substituted amphetamine, acts as a sympathomimetic agent with mild central nervous system stimulant properties. Although approved for therapeutic use in hypotensive states, it is banned by the World Anti-Doping Agency (WADA) due to its performance-enhancing potential. Reports of non-medical use, though rare, have primarily emerged from Southeast Asia and the United States.</div></div><div><h3>Methodology</h3><div>This case series describes 12 consecutive participants presenting with non-medical mephentermine use at a tertiary care addiction treatment facility between September and November 2023. Data were collected through structured interviews, clinical assessments, and confirmatory urine toxicology.</div></div><div><h3>Results</h3><div>Non-medical mephentermine use was identified in 0.71 % of newly registered cases, with half meeting ICD-11 criteria for dependence. All participants were educated males (mean age: 25.6 years, SD = 5.1); 58.3 % were unemployed, and 50 % were married. Most used mephentermine intravenously for performance enhancement in sports, fitness, or occupational settings. The median daily dose was 300 mg (IQR: 183.8–412.5), typically procured from chemists (41.7 %) or gym trainers (25.0 %) at a median cost of INR 275 (IQR: 250–375). Euphoria was reported by 58.3 %, while 66.7 % experienced psychotic symptoms during intoxication. No participant had a comorbid major psychiatric disorder.</div></div><div><h3>Conclusion</h3><div>This series highlights an emerging pattern of intravenous mephentermine misuse among young men in performance-oriented contexts. Given the associated psychosis and cardiovascular risks, clinicians should routinely screen for stimulant use. Community awareness campaigns and stricter regulation of over-the-counter stimulants are crucial for harm reduction.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"108 ","pages":"Article 104525"},"PeriodicalIF":3.8,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143913184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systemic lupus erythematosus masquerading as childhood onset treatment-resistant depressive disorder – A case report","authors":"Manik Inder Singh Sethi ,&nbsp;Guru S. Gowda ,&nbsp;Mude Jeevan Naik ,&nbsp;Shikha Adil ,&nbsp;Satish Suhas ,&nbsp;John P. John ,&nbsp;Venkata Senthil Kumar Reddi","doi":"10.1016/j.ajp.2025.104526","DOIUrl":"10.1016/j.ajp.2025.104526","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"109 ","pages":"Article 104526"},"PeriodicalIF":3.8,"publicationDate":"2025-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143921719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of perioperative dexmedetomidine on postoperative delirium in adult undergoing cardiac surgery: A comprehensive bibliometrix and meta-analysis","authors":"Qiang Fu ,&nbsp;Bhushan Sandeep ,&nbsp;Hong Li ,&nbsp;Bao San Wang ,&nbsp;Xin Huang","doi":"10.1016/j.ajp.2025.104522","DOIUrl":"10.1016/j.ajp.2025.104522","url":null,"abstract":"<div><div>This bibliometrix and meta-analysis aimed to evaluate the efficacy of perioperative dexmedetomidine (DEX) on postoperative delirium (POD) in adult patients undergoing cardiac surgery. A comprehensive search of electronic databases identified 21 randomized controlled trials involving 5210 patients. The primary outcome was the incidence of POD from the first day to seven days post-surgery. The meta-analysis revealed that DEX significantly reduced POD incidence compared to various controls (RR 0.70; 95 % CI 0.54–0.89; P = 0.004). Subgroup analyses showed that DEX was particularly effective when compared to propofol (RR 0.48; 95 % CI 0.30–0.78; P = 0.003). However, no significant differences were observed in the duration of anesthesia, surgery, or ICU/hospital stay. Notably, DEX was associated with a higher incidence of hypotension (RR 1.90; 95 % CI 1.16–3.10; P = 0.01). The study highlights the potential neuroprotective benefits of DEX but underscores the need for careful monitoring of hemodynamic stability. Future research should focus on optimizing DEX dosing protocols and exploring its broader impact on postoperative recovery and patient outcomes.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"108 ","pages":"Article 104522"},"PeriodicalIF":3.8,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143916602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mental health digitalization in Indonesia: Adopting global findings and facing local challenges","authors":"Andi Wahyu Irawan,&nbsp;Anna Ayu Herawati,&nbsp;Binti Isrofin,&nbsp;Sedem Nunyuia Amedome","doi":"10.1016/j.ajp.2025.104515","DOIUrl":"10.1016/j.ajp.2025.104515","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"109 ","pages":"Article 104515"},"PeriodicalIF":3.8,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143917475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric properties of expanded adverse childhood experiences assessment questionnaire at a wellness centre in India","authors":"Gunjan Y. Trivedi ,&nbsp;Pranjal Surana ,&nbsp;Neha Pandya ,&nbsp;Nisarg Patel ,&nbsp;Riri G. Trivedi ,&nbsp;Soundappan Kathirvel ,&nbsp;Anita Kumar","doi":"10.1016/j.ajp.2025.104523","DOIUrl":"10.1016/j.ajp.2025.104523","url":null,"abstract":"<div><div>The original Adverse Childhood Experiences (ACEs) assessment questionnaire with 10 items has been extensively used to assess and identify associations with long-term negative outcomes in mental health, physical health, and behaviour globally. The past three decades of research has also identified a few additional categories of ACEs beyond the original ten questions. However, there is a gap in the Indian context to establish the psychometric properties of the expanded ACE Assessment Questionnaire and explore associations with mental health parameters.</div></div><div><h3>Objective</h3><div>This study evaluated the psychometric properties of an expanded ACE Assessment Questionnaire at a wellness centre in India, incorporating culturally relevant modifications to the original 10 items.</div></div><div><h3>Method</h3><div>An additional six questions (Dangerous neighbourhood, Loss of parent or guardian, Peer bullying or victimization, Peer isolation or rejection, financial difficulty, and Parental fights) based on decades of evidence since the original 10-item questionnaire were added. Internal validity, internal consistency using McDonald’s Omega and item-total correlation followed by principal component analysis were carried out, and confirmatory factor analysis was used to validate the factor structure and model fit indices. Questions which did not contribute to the construct were removed and predictive analysis was conducted using linear regression to predict depression and anxiety using the expanded questionnaire.</div></div><div><h3>Result</h3><div>Two questions (incarceration in the family from the original 10-items questionnaire and loss of parent or guardian from the additional six questions) were removed since they did not contribute significantly to the psychometric properties. The results of the remaining 14-item questionnaire confirm that it is reliable (McDonald’s Omega) and meets content validity criteria based on three-factor structure (Factor 1 - Childhood Maltreatment, Factor 2 - Resource Scarcity &amp; Environmental Distress, Factor 3 - Household Challenges).</div></div><div><h3>Conclusion</h3><div>The findings highlight that additional questions are relevant in the Indian context, and the revised 14-item questionnaire has better psychometric properties while maintaining its conceptual scope in that context. The findings validate these modifications in larger, representative Indian samples to ensure the questionnaire's reliability in assessing childhood adversity and its association with long-term effects.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"108 ","pages":"Article 104523"},"PeriodicalIF":3.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143935116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mindfulness-based stress reduction: A promising approach to managing anxiety in adolescents and college students","authors":"Erfan Ramadhani,&nbsp;Evia Darmawani,&nbsp;Endang Surtiyoni,&nbsp;Arizona,&nbsp;Nurlela,&nbsp;Taty,&nbsp;Syska Purnama Sari,&nbsp;Ramtia Darma Putri,&nbsp;Putri Gusti Maulinsari","doi":"10.1016/j.ajp.2025.104514","DOIUrl":"10.1016/j.ajp.2025.104514","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"108 ","pages":"Article 104514"},"PeriodicalIF":3.8,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143887476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The need for research on AI-driven social media and adolescent mental health","authors":"Dani Fadillah","doi":"10.1016/j.ajp.2025.104513","DOIUrl":"10.1016/j.ajp.2025.104513","url":null,"abstract":"<div><div>The increasing integration of artificial intelligence (AI) in social media platforms has transformed digital interactions, particularly among adolescents. AI-driven algorithms curate highly personalized content, reinforcing behavioral patterns and optimizing engagement. While this enhances user experience, it also raises significant concerns regarding adolescent mental health, including increased anxiety, depression, self-esteem issues, and body dissatisfaction. Despite the growing recognition of social media’s psychological effects, there remains a critical gap in research specifically addressing [how algorithmic mechanisms such as content recommendation systems, engagement prediction tools, and real-time behavior analysis] shape adolescent mental health. This letter advocates for greater scholarly attention to the intersection of AI and adolescent mental health, urging the Asian Journal of Psychiatry to prioritize studies that examine the psychological consequences of AI-curated digital environments. A deeper understanding of this issue is essential for informing clinical interventions, shaping ethical AI policies, and fostering digital literacy initiatives that promote adolescent well-being.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"108 ","pages":"Article 104513"},"PeriodicalIF":3.8,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143894793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accelerated continuous theta burst stimulation of supplementary motor area in management of oromandibular dystonia: A case study","authors":"Mohita Joshi,&nbsp;Ayush Maheshwari,&nbsp;Sujita Kumar Kar","doi":"10.1016/j.ajp.2025.104512","DOIUrl":"10.1016/j.ajp.2025.104512","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"108 ","pages":"Article 104512"},"PeriodicalIF":3.8,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143864584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electroconvulsive therapy for dementia with Lewy bodies: A systematic review and Japanese multicenter survey","authors":"Hiroshige Fujishiro ,&nbsp;Kuniyuki Iwata-Endo ,&nbsp;Ryota Kobayashi ,&nbsp;Fumiyoshi Morikawa ,&nbsp;Manabu Ikeda","doi":"10.1016/j.ajp.2025.104510","DOIUrl":"10.1016/j.ajp.2025.104510","url":null,"abstract":"<div><div>Management of psychiatric symptoms in dementia with Lewy bodies (DLB) is challenging due to hypersensitivity to psychotropic medications. Electroconvulsive therapy (ECT) is a potential therapeutic option for DLB, but its efficacy and safety remain uncertain. We systematically reviewed articles on ECT for DLB, including those published in Japanese-language journals, and surveyed institutions certified by the Japanese Psychogeriatric Society. Of 41 peer-reviewed articles, 32 were from Japan. The proportion of prodromal DLB cases was significantly higher in Japan (34.8 %) than in other countries (9.5 %) (p = 0.044). Cardiac [123I]-metaiodobenzylguanidine scintigraphy and/or striatal dopamine transporter imaging were significantly more frequently in Japan (71.8 %) than in other countries (5.5 %) (p &lt; 0.001). ECT has shown effectiveness in treating depression, catatonia, agitation and psychosis. It was generally considered safe, with transient delirium being the most common side effect, occurring in 16.1 % of Japanese cases. However, current evidence is limited to case studies and lacks randomized controlled trials. The survey confirmed that ECT is widely performed for DLB in Japan, although the number of cases treated varied greatly across institutions. These findings underscore the need for standardized ECT guidelines for DLB. Multicenter studies with standardized assessments and longitudinal follow-up are essential to further research on ECT for DLB, including psychiatric-onset prodromal DLB.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"108 ","pages":"Article 104510"},"PeriodicalIF":3.8,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143869633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mental health towards achieving Sustainable Development Goals: A review of policies in Indonesia","authors":"Suci Megawati,&nbsp;Rafialdo Arifian,&nbsp;Muhammad Alfarizi","doi":"10.1016/j.ajp.2025.104511","DOIUrl":"10.1016/j.ajp.2025.104511","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"108 ","pages":"Article 104511"},"PeriodicalIF":3.8,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143864583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}