Asian journal of psychiatry最新文献

{"title":"Neuroscience in pictures: Functional neurological disorder.","authors":"Christiana Westlin, Matcheri S Keshavan, David L Perez","doi":"10.1016/j.ajp.2025.104449","DOIUrl":"https://doi.org/10.1016/j.ajp.2025.104449","url":null,"abstract":"<p><p>Functional neurological disorder (FND) is a biopsychosocially-complex, prevalent, and potentially disabling neuropsychiatric condition. In this pictorial review, we explore the complexity of FND, from its diagnosis and conceptualization to current mechanistic understandings. We highlight advances in neuroimaging research that have revealed structural and functional brain alterations in FND and discuss a variety of factors that may serve as predisposing vulnerabilities for the development of this condition and/or perpetuate symptoms. This overview is designed as an initial teaching resource to educate trainees, clinicians, and researchers, highlighting core concepts in the literature on FND. Given that mechanistic research in FND is at a relatively early stage and is rapidly evolving, the interested reader should aim to continue updating their mechanistic understanding of FND as research further advances in this area.</p>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"106 ","pages":"104449"},"PeriodicalIF":3.8,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143668946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"‘Brain rot’ – More than just a passing linguistic trend","authors":"Sarthak Kukreja,&nbsp;Nishtha Chawla,&nbsp;Rajesh Sagar","doi":"10.1016/j.ajp.2025.104441","DOIUrl":"10.1016/j.ajp.2025.104441","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"106 ","pages":"Article 104441"},"PeriodicalIF":3.8,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143636766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Structural alterations after repetitive transcranial magnetic stimulation in depression and the link to neurotransmitter profiles.","authors":"Liangliang Ping, Zhaosong Chu, Biao Zhou, Duo Sun, Jiangmin Chu, Jian Xu, Zhenhui Li, Dafu Zhang, Yuqi Cheng","doi":"10.1016/j.ajp.2025.104445","DOIUrl":"https://doi.org/10.1016/j.ajp.2025.104445","url":null,"abstract":"<p><strong>Background: </strong>Repetitive Transcranial Magnetic Stimulation (rTMS) is widely used to treat depression, showing good efficacy and tolerability. However, the neurobiological mechanisms of its antidepressant effects remain unclear. This study explores the potential impact of rTMS on brain structure in depressed patients and its link to neurotransmitter systems.</p><p><strong>Methods: </strong>Thirty-six MDD patients were randomized to receive 5 times per week for 3 weeks of active or sham rTMS targeting the dorsolateral prefrontal cortex (DLPFC) within a double-blind, sham-controlled trial. The Hamilton Depression Rating Scale-17 items (HAMD-17) was used to assess depressive symptoms at baseline and the end of 1 W, 2 W and 3 W after treatment. We analyzed the differences in efficacy between the two groups of patients at different time points, and the grey matter changes of the brain before and after treatment in both groups. In addition, we analyzed the spatial correlations between abnormal grey matter and the neurotransmitter receptors and transporters map.</p><p><strong>Results: </strong>Both the active and sham groups showed significant improvement in depression and anxiety symptoms following rTMS treatment, with the Active group demonstrating greater improvement. Additionally, the Active group exhibited increased grey matter volume in regions associated with the frontal-limbic network, and these changes were significantly correlated with the spatial distribution of D1 receptors.</p><p><strong>Conclusion: </strong>This study suggests that rTMS targeting the left DLPFC produces antidepressant effects by enhancing structural plasticity in the frontal-limbic network, and that dopamine system modulation may underlie rTMS therapeutic effects. These findings provide insight into the neurobiological basis of rTMS for depression treatment.</p>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"107 ","pages":"104445"},"PeriodicalIF":3.8,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mental health of young adults pursuing higher education in Tier-1 cities of India: A cross-sectional study","authors":"Kakollu Suresh ,&nbsp;Aehsan Ahmad Dar","doi":"10.1016/j.ajp.2025.104447","DOIUrl":"10.1016/j.ajp.2025.104447","url":null,"abstract":"<div><div>India, with its vast youth population, grapples with significant mental health issues among young adults in higher education, due to factors such as academic pressure, social isolation, stigma, economic uncertainty, screen time, sedentary lifestyles, and pandemic-related stresses. Though the issue has garnered attention, there's a gap in post-pandemic mental health research for Indian students. This study aims to address this by investigating anxiety, depression, and overall mental well-being among students aged 18–29 in higher educational institutions across eight major Indian cities, categorized by gender, zone, city, and institution type. Using a cross-sectional design and multi-stage sampling, we surveyed 1628 students (47.1 % males, 52.9 % females) using the Mental Health Inventory (MHI-38). Female students reported higher distress levels than males. Students from the Western and Southern zones showed higher positivity and well-being. Kolkata students reported low positivity but superior well-being. Hyderabad students reported low depression levels. Central University students reported more depression, while government arts and science college students reported lower life satisfaction. The majority exhibited moderate to high levels of anxiety (69.9 %), depression (59.9 %), loss of behavioral/emotional control (65.1 %), and distress (70.3 %). These statistics underscore the burden of mental health issues faced by this demographic. Despite the prevalence, a minimal number of young adults accessed mental health services, often due to stigma and cultural biases. This study highlights how the post-pandemic context has exacerbated these barriers, revealing significant mental health issues among participants and underscoring the urgent need for targeted interventions in educational institutions amidst rising suicide rates in this demographic.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"106 ","pages":"Article 104447"},"PeriodicalIF":3.8,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing psychological training in military personnel: Modern approaches, systemic assessments and hands-on recommendations","authors":"Arsen Lokyan ,&nbsp;Svetlana Baghdasaryan ,&nbsp;Hayk Hovhannisyan","doi":"10.1016/j.ajp.2025.104442","DOIUrl":"10.1016/j.ajp.2025.104442","url":null,"abstract":"<div><h3>Background</h3><div>The level of combat readiness, including psychological training of military personnel, is crucial for mobilizing physical, mental, and psychological resources, enabling them to demonstrate appropriate behaviors in high-pressure situations. This study aims to critically analyse contemporary approaches to the psychological training of servicemen, identifying both strengths and areas for improvement.</div></div><div><h3>Methods</h3><div>By examining the mental states of Armenian servicemen who participated in the 44-day Artsakh War and the September 2022 military operations, this research seeks to develop evidence-based, practical recommendations that enhance the psychological resilience and effectiveness of military personnel. The theoretical and methodological framework of this study is grounded in a comprehensive analysis, comparison, and synthesis of existing literature, coupled with detailed substantive and statistical assessments of the collected research data.</div></div><div><h3>Findings</h3><div>The findings suggest that training under conditions that closely mimic real combat scenarios significantly contributes to the development of emotional resilience, transforming stress into a motivating factor rather than a disruptive one. Regular exercises and training to improve emotional intelligence are crucial in helping servicemen manage stress, stay motivated, and maintain composure under duress, enhancing cognitive flexibility and teamwork. Moreover, integrating biofeedback technology into psychological training offers additional benefits by helping servicemen control physiological responses and develop coping mechanisms.</div></div><div><h3>Interpretation</h3><div>Analysis further emphasizes combat readiness, psychophysiological state, personal qualities, and mutual trust as key factors influencing combat effectiveness. These findings underline the importance of strategically designed psychological training programs that prioritize emotional stability, cognitive flexibility, and stress management, ensuring that military personnel are well-equipped to handle the psychological demands of modern warfare.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"106 ","pages":"Article 104442"},"PeriodicalIF":3.8,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Online dispensing of benzodiazepines can be an emerging threat for suicide prevention in Bangladesh: A case and potential preventive measures","authors":"S M Yasir Arafat","doi":"10.1016/j.ajp.2025.104446","DOIUrl":"10.1016/j.ajp.2025.104446","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"106 ","pages":"Article 104446"},"PeriodicalIF":3.8,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143600835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical effectiveness and economic evaluation of an online mental health self-care program for mothers in Korea: A non-randomized comparative study","authors":"Hyein Jeong,&nbsp;Soobin Jang,&nbsp;Bo-Hyoung Jang,&nbsp;Kyeong Han Kim,&nbsp;Seong-Gyu Ko","doi":"10.1016/j.ajp.2025.104444","DOIUrl":"10.1016/j.ajp.2025.104444","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"106 ","pages":"Article 104444"},"PeriodicalIF":3.8,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143642857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Functional near-infrared spectroscopy (fNIRS) in patients with major depressive disorder, generalized anxiety disorder and their comorbidity: Comparison with healthy controls” [Asian J. Psychiatry 105 (2025) 104382]","authors":"Yuqi Shen ,&nbsp;Boyuan Wu ,&nbsp;Jikai Yu ,&nbsp;Lan Mou ,&nbsp;Zefeng Wang ,&nbsp;Xinhua Shen","doi":"10.1016/j.ajp.2025.104432","DOIUrl":"10.1016/j.ajp.2025.104432","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"106 ","pages":"Article 104432"},"PeriodicalIF":3.8,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143561779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Most influential symptoms in the early detection of clinical high risk for psychosis in Indonesia: A basic symptom network","authors":"Tri Kurniati Ambarini ,&nbsp;Nurul Hartini ,&nbsp;Endang Surjaningrum ,&nbsp;Ahmad Chusairi ,&nbsp;Dhany Arifianto ,&nbsp;Zain Budi Syulthoni ,&nbsp;Irma Melyani Puspitasari ,&nbsp;Rosatyani Puspita Adiati ,&nbsp;Frauke Schultze-Lutter","doi":"10.1016/j.ajp.2025.104430","DOIUrl":"10.1016/j.ajp.2025.104430","url":null,"abstract":"<div><div>Basic symptoms (BS) are subtle, self-experienced disturbances in mental processes. Cognitive, visual and acoustic BS were included in clinical-high risk criteria for psychosis (CHR-P). So far, their interplay has been studied only in Western samples and always in concert with other symptoms, such as (attenuated) psychotic symptoms. Thus, we studies the interrelation of the 56 BS assessed with the ‘Schizophrenia Proneness Instrument, Adult version’, in an Indonesian sample of CHR-P patients (N = 108) 16–30 years-of-age, 18.95 % male) according to BS criteria using network analysis. The used estimator partially correlates with the Gaussian graphical model (GGM) and graph module. Model selection uses regularization techniques by setting λ = 0.05. The most central and traversed nodes in the robust, stable network were visual disturbances—‘near- and tele-vision’, ‘disturbances of the perception of straight lines/contours’ and ‘micropsia, macropsia’. Visual disturbances were also predominately involved in the 16 strongest edges, thereby linking strongly with alienation experiences. Contrary to networks in Western samples in that cognitive BS played a central and important role, subjective visual disturbances seem to play an important role in the possible emergence and maintenance of BS, in particular of alienation experiences, in Indonesian patients with CHR-P. Future studies should therefore study this potential role longitudinally along with their neurobio/cognitive underpinnings. Furthermore, it should be studies, if cognitive-behavioral therapy as suggested for alienation experiences may prevent progression and reduce symptom load.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"106 ","pages":"Article 104430"},"PeriodicalIF":3.8,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143629348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Special issue on “Ketamine, MDMA, and psychedelics in the treatment of neuropsychiatric disorders”","authors":"Kenji Hashimoto,&nbsp;Xingming Wang,&nbsp;Jichun Zhang","doi":"10.1016/j.ajp.2025.104426","DOIUrl":"10.1016/j.ajp.2025.104426","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"106 ","pages":"Article 104426"},"PeriodicalIF":3.8,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143579826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}