Warut Aunjitsakul , Kanthee Anantapong , Nisan Werachattawan , Kreuwan Jongbovonwiwat , Rasmon Kalayasiri , Daruj Aniwattanapong , Poom Chompoosri , Andre Tay Teck Sng , Samuel Cheng Eng Teck , Sanjiv Nair Sasidharan , David Choon Liang Teo , Petrin Redayani Lukman , Sylvia Detri Elvira , Alfi Fajar Almasyhur , Nik Ruzyanei Nik Jaafar , Farah Nabila , Jiann Lin Loo , Nuur Asyikin binti Mohd Shukor , Eric Bui , Vu Tuong Vi , César A. Alfonso
{"title":"Perspectives on psychotherapy in Southeast Asia: Insights from psychiatrists and trainees (Part I: Attitudes, current practices and training preferences)","authors":"Warut Aunjitsakul , Kanthee Anantapong , Nisan Werachattawan , Kreuwan Jongbovonwiwat , Rasmon Kalayasiri , Daruj Aniwattanapong , Poom Chompoosri , Andre Tay Teck Sng , Samuel Cheng Eng Teck , Sanjiv Nair Sasidharan , David Choon Liang Teo , Petrin Redayani Lukman , Sylvia Detri Elvira , Alfi Fajar Almasyhur , Nik Ruzyanei Nik Jaafar , Farah Nabila , Jiann Lin Loo , Nuur Asyikin binti Mohd Shukor , Eric Bui , Vu Tuong Vi , César A. Alfonso","doi":"10.1016/j.ajp.2025.104597","DOIUrl":"10.1016/j.ajp.2025.104597","url":null,"abstract":"<div><h3>Introduction</h3><div>Psychotherapy is an evidence-based treatment for mental disorders. Despite its global development, neuroscientific advances, and measurable efficacy, attitudes toward psychotherapy in Southeast Asia (SEA) remain underexplored, particularly among psychiatrists and psychiatric trainees.</div></div><div><h3>Objectives</h3><div>This study aimed to assess attitudes toward psychotherapy, its current use in clinical practice, and stated preferences for future training among psychiatrists and trainees in SEA.</div></div><div><h3>Methods</h3><div>A cross-sectional online survey was conducted across Indonesia, Malaysia, Singapore, Thailand, and Vietnam. The questionnaire explored perspectives on psychotherapy and its integration into practice. Data were analyzed descriptively and comparatively.</div></div><div><h3>Results</h3><div>Of 253 respondents, 149 (58.9 %) were psychiatrists and 104 (41.1 %) were psychiatric trainees. Both groups exhibited positive attitudes toward psychotherapy, recognizing its professional value, clinical efficacy, and integration with pharmacotherapy. Combination therapy was frequently used; pharmacotherapy dominated for severe disorders, psychotherapy for adjustment and personality disorders, and ECT primarily for schizophrenia, depression, and bipolar disorder. Commonly used therapies include cognitive behavioral therapy, supportive psychotherapy, and mindfulness-based approaches. Psychiatrists favored expanding the number of psychotherapists, while trainees expressed stronger interest in advanced psychodynamic techniques and psychoanalysis. Both groups advocated for additional training in evidence-based psychotherapies and foundational clinical skills.</div></div><div><h3>Conclusion</h3><div>Psychiatrists and trainees in SEA value psychotherapy and its relevance to both clinical practice and everyday life. There is a general preference for integrating psychotherapy with psychopharmacological treatment. Future efforts should focus on enhancing psychotherapy training, addressing cultural adaptations, and overcoming systemic challenges to improve access and efficacy of interventions in SEA.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104597"},"PeriodicalIF":3.8,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144365139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yang-Chieh Brian Chen , Chih-Wei Hsu , Kuo-Chuan Hung , Chih-Sung Liang , Ping-Tao Tseng , Yu-Kang Tu
{"title":"Dose-effect trajectory of lumateperone in schizophrenia: Evidence from a systematic review and meta-analysis of randomized controlled trials","authors":"Yang-Chieh Brian Chen , Chih-Wei Hsu , Kuo-Chuan Hung , Chih-Sung Liang , Ping-Tao Tseng , Yu-Kang Tu","doi":"10.1016/j.ajp.2025.104591","DOIUrl":"10.1016/j.ajp.2025.104591","url":null,"abstract":"<div><h3>Background</h3><div>The optimal dose of lumateperone for treating schizophrenia remains unclear. We examined its dose-response relationship for efficacy and acceptability.</div></div><div><h3>Methods</h3><div>We searched major databases (e.g. PubMed, EMBASE, Cochrane), and grey literature from inception to January 20, 2025 (INPLASY202510038) for randomized controlled trials (RCTs) comparing lumateperone with placebo in schizophrenia. We excluded non-peer-reviewed studies and those lacking a placebo group or involved non-schizophrenic patients. The Cochrane Risk of Bias Tool was used for risk of bias assessment. We used a one-step dose-response meta-analysis (DRMA) with a random-effects model to calculate the effect sizes as standardized mean differences (SMDs) and risk ratios (RRs) with 95 % confidence intervals (CIs).</div></div><div><h3>Results</h3><div>688 patients from two RCTs received placebo or lumateperone. Lumateperone 42 mg significantly improved the Positive and Negative Syndrome Scale (PANSS) total score (SMD = −0.29, 95 % CI: −0.47 to −0.10), PANSS positive symptom score (SMD = −0.41, 95 % CI: −0.64 to −0.18), and responder rate (RR = 1.52, 95 % CI: 1.16–2.01), as well as marginally improved the PANSS negative symptom score (SMD = −0.17, 95 % CI: −0.34–0.01). Higher doses (>42–63 mg) were associated with increased rates of oral dryness/thirst, nausea/vomiting, somnolence, and dizziness. No dose-response relationship was found for dropout rates, headache, or extrapyramidal symptoms. A limitation of this study is the small number of available RCTs.</div></div><div><h3>Conclusions</h3><div>Lumateperone 42 mg appears to offer the most favorable balance of efficacy and side effects for the treatment of schizophrenia.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104591"},"PeriodicalIF":3.8,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144365138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francisco Antonio Coelho Junior , Pedro Marques-Quinteiro , Cristiane Faiad , Keila Roberta Mendonça Tavares , Helga Cristina Hedler, Tássia Silva Rendeiro
{"title":"Factors that help to understand the increase in the number of suicide cases among public security professionals in Brazil: What can we learn from the experience and culture of Japan?","authors":"Francisco Antonio Coelho Junior , Pedro Marques-Quinteiro , Cristiane Faiad , Keila Roberta Mendonça Tavares , Helga Cristina Hedler, Tássia Silva Rendeiro","doi":"10.1016/j.ajp.2025.104588","DOIUrl":"10.1016/j.ajp.2025.104588","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104588"},"PeriodicalIF":3.8,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144331361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahsan Nazeer , Nazish Imran , Sadiq Naveed , Maha AlMuraikhi , Imran Ijaz Haider , Afzal Javed
{"title":"Developing suicide screening and prevention guideline for the children and adolescents of Pakistan: The first step","authors":"Ahsan Nazeer , Nazish Imran , Sadiq Naveed , Maha AlMuraikhi , Imran Ijaz Haider , Afzal Javed","doi":"10.1016/j.ajp.2025.104586","DOIUrl":"10.1016/j.ajp.2025.104586","url":null,"abstract":"<div><div>This paper focuses on developing suicide screening and prevention guidelines by the Pakistan Psychiatric Research Center’s Task Force of national and international experts, specifically for children and adolescents in Pakistan. The discussion included screening for youth in medical and non-medical settings using internationally recognized, validated, and easy-to-use screening instruments. Recommendations were also made to advance beyond the current paradigm in Pakistan's mental health landscape by exploring essential next steps to reduce youth suicide rates by 2030. Pakistan has an estimated population of 240 million, with 41 % under the age of 15. It is believed that around 35 % of Pakistani youth experience emotional difficulties, with stress, anxiety, and depression being the most pressing concerns within this group. Key factors contributing to these challenges include academic pressure, intensified by societal and parental expectations, excessive social media use, as well as family dynamics, which encompass strict parenting, and a perceived lack of emotional support. Existing studies have identified an increased risk of suicide among Pakistani adolescents aged 15–18, with the ingestion of poisonous substances as the most common method, followed by hanging, jumping in front of trains, and firearm use. Systemic barriers, including limited financial resources, a shortage of trained mental health professionals, and societal stigma, impede progress. Nevertheless, ample opportunities for improvement exist. Raising public awareness to combat stigma, promoting inter-sectoral collaboration, and enhancing policy implementation are essential steps. A multi-stakeholder approach that includes policymakers, educators, families, and young people is crucial for building a sustainable mental health ecosystem.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104586"},"PeriodicalIF":3.8,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144298524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"When likes lead to labels: The social media self-diagnosis phenomenon","authors":"Muaz Ahmed, Faqiha Fatima Cheema, Savaira Rehman","doi":"10.1016/j.ajp.2025.104589","DOIUrl":"10.1016/j.ajp.2025.104589","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104589"},"PeriodicalIF":3.8,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144313208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yi-chen Jin , Jing Li , Fang-biao Tao , Ying Sun , Lloyd Kolbe
{"title":"National challenges and national actions to improve child and adolescent mental health in China","authors":"Yi-chen Jin , Jing Li , Fang-biao Tao , Ying Sun , Lloyd Kolbe","doi":"10.1016/j.ajp.2025.104584","DOIUrl":"10.1016/j.ajp.2025.104584","url":null,"abstract":"<div><div>With the continuous development of the social economy, the disease spectrum of children and adolescents in China has undergone new changes, and psychological health issues have become increasingly prominent. The commentary examines the critical challenges and national actions aimed at improving child and adolescent mental health in China.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104584"},"PeriodicalIF":3.8,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144271704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Insomnia moderates the association between positive psychotic-like experience and self-injurious thoughts and behaviors: A large-scale replication and extension study among Chinese college students","authors":"Pu Peng , Yanan Zhou , Hongyu Zou","doi":"10.1016/j.ajp.2025.104583","DOIUrl":"10.1016/j.ajp.2025.104583","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104583"},"PeriodicalIF":3.8,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144255053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shunsuke Nonaka , Ji Yeon Kim, Rae Na Kang, Eun Suk Kim, Hiroaki Kubo, Tomoya Takeda, Mi Sun Kwak, Min Gi Kang, Motohiro Sakai
{"title":"Bridging cultures in Hikikomori research: A Japan–Korea international collaborative approach to family perspectives","authors":"Shunsuke Nonaka , Ji Yeon Kim, Rae Na Kang, Eun Suk Kim, Hiroaki Kubo, Tomoya Takeda, Mi Sun Kwak, Min Gi Kang, Motohiro Sakai","doi":"10.1016/j.ajp.2025.104570","DOIUrl":"10.1016/j.ajp.2025.104570","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104570"},"PeriodicalIF":3.8,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144255052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effects of non-invasive brain stimulation on cognitive impairment in depression: A systematic review and meta-analysis","authors":"Xin Xia , Chuan Huang , Zhixin Chen , Wenwen Lei , Yuchuan Yue","doi":"10.1016/j.ajp.2025.104573","DOIUrl":"10.1016/j.ajp.2025.104573","url":null,"abstract":"<div><h3>Background</h3><div>Cognition is commonly compromised in depression, and non-invasive brain stimulation (NIBS) has been well-established in the treatment of depression, but its efficacy for treating cognitive deficit has not been fully elucidated. Based on the available evidence on NIBS, we conducted a meta-analysis to systematically assess the efficacy of NIBS in improving cognitive deficits in depressed patients.</div></div><div><h3>Methods</h3><div>A literature search was conducted in PubMed, Web of Science, Embase, Ovid MEDLINE, and Cochrane Library databases up to February 20, 2025. we separately assessed the effects on: global cognitive function, learning and memory, working memory, language, psychomotor speed, attention, visuospatial ability, and domains of executive function (including attentional switching, verbal fluency, inhibitory control, and cognitive flexibility).</div></div><div><h3>Results</h3><div>A total of 23 randomized controlled trials (n = 1267) were included in this study. Analyses showed that NIBS produced significant improvement in the domains of global cognitive function (SMD=0.24, 95 % CI [0.03, 0.46]) and learning and memory (SMD=0.46, 95 % CI [0.06, 0.85]). Subgroup analyses showed that transcranial magnetic stimulation (TMS) was significantly better than the placebo control group in terms of global cognitive function improvement (SMD=0.32, 95 % CI [0.07, 0.57]). However, other cognitive dimensions showed no significant improvement with NIBS</div></div><div><h3>Conclusion</h3><div>Our findings suggest that NIBS has significant efficacy on global cognitive function, learning and memory in depressed patients. Effects on other domains were not significant. Future high-quality studies are needed to validate which stimulation programs are most effective.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104573"},"PeriodicalIF":3.8,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144239901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}