Asian journal of psychiatry最新文献

{"title":"Developing and pilot testing a collaborative, locally contextualized supported employment program for persons with mental illness in Chennai, Tamil Nadu","authors":"Aravind Guru ,&nbsp;Abhinav Ajay ,&nbsp;J. Selva Savari Raj ,&nbsp;Harini Kannan ,&nbsp;K.R. Manjukashika ,&nbsp;C.H. Manisha ,&nbsp;Durairaj Jothilakshmi ,&nbsp;T. Siva Ilango ,&nbsp;P.P. Kannan ,&nbsp;Sharon Joe Daniel ,&nbsp;Jayakumar Menon ,&nbsp;R. Mangala ,&nbsp;Vijaya Raghavan","doi":"10.1016/j.ajp.2025.104633","DOIUrl":"10.1016/j.ajp.2025.104633","url":null,"abstract":"<div><h3>Background</h3><div>Employment is a key factor aiding in the recovery and social reintegration of persons with mental illness (PwMI). However, the PwMI demographic in India faces high rates of unemployment, highlighting a need for the development of structured, culturally sensitive, and regionally adapted supported employment programs.</div></div><div><h3>Aim</h3><div>This study aimed to develop and pilot test a supported employment program designed to enhance job opportunities for PwMI in Chennai, India.</div></div><div><h3>Methods</h3><div>A desk review was conducted to examine existing employment support models for PwMI in India. Qualitative interviews were held with key stakeholders, including PwMI, caregivers, mental health professionals, and employers, to identify employment barriers and facilitators. An expert panel used these insights to co-design and develop a locally relevant supported employment program. The program was pilot-tested in Chennai from May 2023 to May 2024. Job placement and dropout rates were used to assess feasibility and effectiveness.</div></div><div><h3>Results</h3><div>Of the 213 participants, 63 secured competitive employment, 37 were enrolled in skill training programs, and 40 remained in active job placement efforts. However, 54 individuals were deemed not readily employable due to functional limitations, and 16 dropped out. A total of 12 employers and 20 training organizations partnered with the program, contributing to its 62.8 % job placement rate.</div></div><div><h3>Conclusion</h3><div>The study demonstrates the operational potential of a regionally adapted supported employment program for PwMI in India. Future research should examine long-term job retention, workplace integration, and employment sustainability.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"111 ","pages":"Article 104633"},"PeriodicalIF":3.8,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144703280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic applications of 3D printing in psychiatry: Current status and future possibilities","authors":"Tien-Wei Hsu ,&nbsp;Ping-Tao Tseng ,&nbsp;Yu-Chen Kao,&nbsp;Chih-Sung Liang","doi":"10.1016/j.ajp.2025.104634","DOIUrl":"10.1016/j.ajp.2025.104634","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"111 ","pages":"Article 104634"},"PeriodicalIF":3.8,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144695108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comorbidity landscape of unipolar depression: towards precision psychiatry","authors":"Ming Zheng","doi":"10.1016/j.ajp.2025.104627","DOIUrl":"10.1016/j.ajp.2025.104627","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"111 ","pages":"Article 104627"},"PeriodicalIF":3.8,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144703282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancing neuroscience education in psychiatry residency: A survey of current attitudes, trends, and challenges","authors":"Yelu Zhang ,&nbsp;Paulo Lizano ,&nbsp;Matcheri Keshavan","doi":"10.1016/j.ajp.2025.104630","DOIUrl":"10.1016/j.ajp.2025.104630","url":null,"abstract":"<div><h3>Objective</h3><div>This study assesses the current state of neuroscience education in psychiatry residency programs, focusing on attitudes, emerging trends, and perceived barriers to effective training by multiple stakeholders.</div></div><div><h3>Methods</h3><div>An online survey was distributed to psychiatry residency programs in the U.S., targeting department chairs, faculty, program directors, practicing psychiatrists, and trainees. The survey included questions on training experiences, preferred teaching methods, and perceived challenges. Descriptive statistics were used to analyze responses.</div></div><div><h3>Results</h3><div>A total of 106 responses were collected from 26 U.S. states. 52.8 % of respondents received neuroscience training throughout all four years of residency. 74.5 % reported receiving two months of neurology rotations but a higher proportion of respondents shared preference for longer neurology rotation training. Key barriers to effective neuroscience education included insufficient faculty expertise, inadequate curricula, and limited faculty interest. Respondents favored teaching methods such as clinical case applications, neuroimaging, and research integration. Nearly all participants agreed that stronger neuroscience education improves patient care and helps reduce stigma toward psychiatric disorders.</div></div><div><h3>Conclusion</h3><div>The study builds upon prior surveys in neuroscience education in psychiatry residency training, while focusing on most recent trends and attitudes. Findings highlight the need for longitudinal and clinically relevant neuroscience training in psychiatry residencies, as well as areas of knowledge gaps including neuromodulation and neuroimaging. Findings also highlight the need to improve curriculum design and integration.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"111 ","pages":"Article 104630"},"PeriodicalIF":4.5,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144724432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of neuroinflammation in schizophrenia: Focus on Th17 cells functions","authors":"Mikhail Melnikov ,&nbsp;Anna Lopatina ,&nbsp;Anastasiya Sviridova ,&nbsp;Dmitriy Chugunov ,&nbsp;Theofanis Vavilis ,&nbsp;Vasileios-Periklis Stamatellos ,&nbsp;Eleni Stamoula ,&nbsp;Marco Cosentino","doi":"10.1016/j.ajp.2025.104629","DOIUrl":"10.1016/j.ajp.2025.104629","url":null,"abstract":"<div><div>Schizophrenia is a severe mental disorder associated with behavioural, cognitive, and emotional impairments. There are several leading theories on schizophrenia etilology, including genetic, neurotransmitter (dopamine and GABA-glutamate are the leading ones), immunological (microglial, cytokine, kynurenine) and neurodevelopmental (neuro-ontogenetic and neurodegenerative) theories. Despite the fact that in recent decades, the greatest efforts have been directed towards testing and developing genetic and neurotransmitter (including dopamine) theories, the recent evidence suggests that immunological aspects, in particular neuroinflammation (cytokine hypothesis) may play an important role in schizophrenia. Neuroinflammation in schizophrenia is thought to be mediated primarily by the activation of resident immune cells such as microglia. However, peripheral immune cells, which migrate through the blood-brain barrier into the central nervous system (CNS) are also involved in the development of neuroinflammation. Among the infiltrating cells that cause neuroinflammation, CD4⁺ T helper (Th) 17 cells attract the most attention. These cells produce proinflammatory cytokines, increase the permeability of the blood-brain barrier, and activate resident microglia. The critical role of Th17 cells in the development of demyelinating and neurodegenerative diseases of the CNS has been established. In addition, the pathogenic role of Th17 cells in mental disorders such as depression and general anxiety disorder has also been demonstrated. In this report, we reviewed the recent evidence supporting the involvement of the Th17 cells in the pathogenesis of schizophrenia. Based on <em>in vivo</em> and <em>in vitro</em> studies, we suggest that Th17 cells could be considered as a promising additional therapeutic target in schizophrenia and deserve further investigation.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104629"},"PeriodicalIF":3.8,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144654543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health literacy and its relationship with mental health: A nationwide Korean survey","authors":"Yoo Jeong Lee ,&nbsp;Ki Dong Ko ,&nbsp;In Cheol Hwang,&nbsp;Hong Yup Ahn","doi":"10.1016/j.ajp.2025.104628","DOIUrl":"10.1016/j.ajp.2025.104628","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"111 ","pages":"Article 104628"},"PeriodicalIF":3.8,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144655516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"On dosing equity, scientific responsibility, and what remains unsaid","authors":"Carlos De las Cuevas","doi":"10.1016/j.ajp.2025.104626","DOIUrl":"10.1016/j.ajp.2025.104626","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104626"},"PeriodicalIF":3.8,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144632140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-acting injectable antipsychotics in the treatment of schizoaffective disorder: A retrospective mirror image study for hospitalizations and treatment costs","authors":"Bengisu Büşra Mammadov ,&nbsp;Eren Yildizhan ,&nbsp;Nesrin Buket Tomruk","doi":"10.1016/j.ajp.2025.104625","DOIUrl":"10.1016/j.ajp.2025.104625","url":null,"abstract":"<div><div>This study investigates the effect of long-acting injectable antipsychotic (LAI) use on psychiatric hospitalizations and treatment costs in schizoaffective disorder. In our retrospective, naturalistic mirror image study, we evaluated the medical records of patients attending to the community mental health centers affiliated to our hospital with the diagnosis of schizoaffective disorder during last 5 years. Comparisons were made for 43 patients using LAI treatment regarding hospitalizations and treatment costs for the one-year period before and after initiation of LAI with additional comparisons according to the class of LAI. The number and length of hospitalizations were lower after LAI treatment and the cost of drug treatment was higher but the cost of hospitalization was lower compared to the previous year. The cost of medication and total treatment costs in the first year of treatment was higher for patients using second-generation LAI than patients using first-generation LAI. After the initiation of LAI treatment, for the first-generation LAI group; there was no significant difference between the medication costs, but hospitalization costs and total treatment costs were lower and for the second-generation LAI group; the cost of medications was higher, the cost of hospitalizations was lower and the total cost of treatment was higher. Although the overall treatment cost rises due to the high prices of second-generation LAIs relative to hospitalization costs in our country, the reduction in hospitalizations associated with both groups of LAI in schizoaffective disorder is an outstanding outcome that is important for both patients and the community.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104625"},"PeriodicalIF":3.8,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144632139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brief facial emotional recognition tool for indian population: Development and validation","authors":"Sandeep Grover,&nbsp;Swapnajeet Sahoo,&nbsp;BN Subodh,&nbsp;Jahanavi Khatri,&nbsp;Amaneet Kaur Gandhi","doi":"10.1016/j.ajp.2025.104620","DOIUrl":"10.1016/j.ajp.2025.104620","url":null,"abstract":"<div><h3>Background</h3><div>Facial emotion recognition is an essential component of social cognition. Due to cultural differences in emotional expression and recognition, assessment of facial emotion requires culture and ethnic specific instruments. Currently available instruments in the Indian context have limitations of copyright issues and longer version that limit their use. Hence, there is a need for brief, culturally validated tools for the Indian population.</div></div><div><h3>Objective</h3><div>This study aimed to develop an ecologically valid facial emotion recognition tool and validate the same among the Indian population.</div></div><div><h3>Methods</h3><div>The study was conducted in three phases at a tertiary care center. In Phase 1, nine mental health professionals depicted seven emotions, yielding 1636 photographs. After multiple stages of expert review and participant labeling, 130 photographs were shortlisted. In Phase 2, 33 healthy mental health professionals validated these images across two sessions, and images with over 80 % concordance were selected, resulting in a final set of 21 images. In Phase 3, the tool was administered to 45 patients with schizophrenia, 45 biological relatives, and 38 healthy controls.</div></div><div><h3>Results</h3><div>Patients with schizophrenia demonstrated significantly lower recognition of negative emotions (anger, disgust, fear) compared to healthy controls. Biological relatives also showed poorer recognition compared to healthy controls, particularly for anger, but no significant difference was observed between patients and their relatives. The Cronbach’s alpha value for the tool was 0.631.</div></div><div><h3>Conclusion</h3><div>The newly developed brief facial emotion recognition tool is a reliable, and culturally appropriate tool for facial emotion recognition in the Indian context, with potential utility in both clinical and research settings.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"110 ","pages":"Article 104620"},"PeriodicalIF":3.8,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144632138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A call to action to curb the use of punitive psychiatry and criminalization of not wearing a hijab: Differential diagnosis civil disobedience from antisocial personality disorder","authors":"Bijan Pirnia","doi":"10.1016/j.ajp.2025.104623","DOIUrl":"10.1016/j.ajp.2025.104623","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"111 ","pages":"Article 104623"},"PeriodicalIF":3.8,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144604386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}