Asia Pacific journal of clinical nutrition最新文献

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Hypertension and its associated risk factors in tuberculosis patients: A hospital based cross-sectional study. 肺结核患者高血压及其相关危险因素:一项基于医院的横断面研究
IF 1.6 4区 医学
Asia Pacific journal of clinical nutrition Pub Date : 2026-02-01 DOI: 10.6133/apjcn.202602_35(1).0009
Yuanyuan Tan, Xin Gao, Yanhong Li, Xiaofang Li, Yufeng Liu, Xiaona Li, Taoli Yan, Qiaoyi Yan, Evert G Schouten, Frans J Kok, Qiuzhen Wang
{"title":"Hypertension and its associated risk factors in tuberculosis patients: A hospital based cross-sectional study.","authors":"Yuanyuan Tan, Xin Gao, Yanhong Li, Xiaofang Li, Yufeng Liu, Xiaona Li, Taoli Yan, Qiaoyi Yan, Evert G Schouten, Frans J Kok, Qiuzhen Wang","doi":"10.6133/apjcn.202602_35(1).0009","DOIUrl":"10.6133/apjcn.202602_35(1).0009","url":null,"abstract":"<p><strong>Background and objectives: </strong>Tuberculosis (TB) is associated with a number of non-communicable diseases including hypertension. The aim of this study is to determine the prevalence of hypertension in TB patients and investigate its associated risk factors.</p><p><strong>Methods and study design: </strong>A hospital-based cross-sectional study was conducted in Qingdao, China (2011-2019). Data on demographics, medical history, and lifestyle were collected via questionnaire. Blood pressure was measured at admission. Logistic regression identified hypertension risk factors.</p><p><strong>Results: </strong>2159 TB patients were included in total in the final analysis. Among them, 485 (22.5%) were hypertensive. After adjusting for dietary sodium and potassium intake, marital status, retreatment, physical activity and smoking index, multivariate logistic regression showed that hemoglobin (HGB) ≥143 (OR, 95% CI: 1.74, 1.08~2.79) , age >35 (OR, 95% CI: 2.93, 1.87 ~ 4.59), male gender (OR, 95% CI: 1.77, 1.13~2.77), overweight or obesity (OR, 95% CI: 2.04, 1.42~2.93) , heavy drinking (OR, 95% CI: 1.76, 1.19~2.59) and concurrent DM (OR, 95% CI: 1.54, 1.09~2.17) were associated with increased risk of hypertension in TB patients, whereas high education level (OR, 95% CI: 0.47, 0.26~0.85) served as a protective factor.</p><p><strong>Conclusions: </strong>Nearly 25% of TB patients have prevalent hypertension at admission. High HGB, being overweight or obese, heavy drinking, male gender and concurrent DM are associated with higher odds of hypertension in TB, while a higher education level serves as a protective factor. Our study provides important evidence for understanding the prevalence of hypertension in TB, underlying the double burden of TB and hypertension.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"35 1","pages":"91-98"},"PeriodicalIF":1.6,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12823255/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146017248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between dietary protein intake and preterm birth in pregnant women with gestational diabetes mellitus: the WeBirth cohort study. 妊娠期糖尿病孕妇膳食蛋白质摄入量与早产之间的关系:WeBirth队列研究
IF 1.6 4区 医学
Asia Pacific journal of clinical nutrition Pub Date : 2026-02-01 DOI: 10.6133/apjcn.202602_35(1).0015
Meiqi Shi, Zelei Miao, Yuhua Yin, Meng Ye, Xuhong Wang, Sha Lu, Yingying Wu, Yuanqing Fu, Wensheng Hu
{"title":"Association between dietary protein intake and preterm birth in pregnant women with gestational diabetes mellitus: the WeBirth cohort study.","authors":"Meiqi Shi, Zelei Miao, Yuhua Yin, Meng Ye, Xuhong Wang, Sha Lu, Yingying Wu, Yuanqing Fu, Wensheng Hu","doi":"10.6133/apjcn.202602_35(1).0015","DOIUrl":"10.6133/apjcn.202602_35(1).0015","url":null,"abstract":"<p><strong>Background and objectives: </strong>The distribution of dietary macronutrients is essential for blood glucose management in patients with gestational diabetes mellitus (GDM). However, the relationship between dietary protein intake and the risk of preterm birth remains unclear. Here, we aim to investigate the prospective association between dietary protein intake and preterm birth in patients with GDM.</p><p><strong>Methods and study design: </strong>We included 1756 GDM patients and assessed dietary protein patterns by constructing total protein index (TPI), animal protein index (API), and plant protein index (PPI) using data collected from food frequency questionnaires (FFQ).</p><p><strong>Results: </strong>We found that individuals in the highest quartile of TPI (OR: 2.75, 95% CI: 0.81 to 9.22) and API (OR: 3.64, 95% CI: 1.48 to 9.47) had a significantly higher risk of preterm birth compared to those in the lowest quartile.</p><p><strong>Conclusions: </strong>This study suggests that increasing protein intake, especially from animal sources, was associated with a greater risk of preterm birth in patients with GDM.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"35 1","pages":"158-163"},"PeriodicalIF":1.6,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12823256/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146017194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations between vitamin D insufficiency, health beliefs, and quality of life in metabolic syndrome: A northeastern Taiwanese community study. 代谢综合征患者维生素D不足、健康信念与生活品质之关系:一项台湾东北社区研究。
IF 1.6 4区 医学
Asia Pacific journal of clinical nutrition Pub Date : 2026-02-01 DOI: 10.6133/apjcn.202602_35(1).0012
Sue-Hsien Chen, Shu-Ching Chen, Yo-Ping Lai, Pin-Hsuan Chen, Kun-Yun Yeh
{"title":"Associations between vitamin D insufficiency, health beliefs, and quality of life in metabolic syndrome: A northeastern Taiwanese community study.","authors":"Sue-Hsien Chen, Shu-Ching Chen, Yo-Ping Lai, Pin-Hsuan Chen, Kun-Yun Yeh","doi":"10.6133/apjcn.202602_35(1).0012","DOIUrl":"10.6133/apjcn.202602_35(1).0012","url":null,"abstract":"<p><strong>Background and objectives: </strong>The impact of Vitamin D on health-related quality of life (HRQoL) and health beliefs in specific populations, such as Taiwanese adults, remains underexplored. Metabolic syndrome (MetS) and vitamin D insufficiency (VDI) are prevalent global health concerns. However, the association between VDI and MetS is still inconclusive, particularly in relation to HRQoL within the framework of the health belief model (HBM). This study aimed to investigate the associations among VDI, HBM constructs, HRQoL, and MetS in a community-based population of Taiwanese adults.</p><p><strong>Methods and study design: </strong>This cross-sectional study recruited 1015 Taiwanese patients aged ≥30 years between August 2020 and July 2023. Sociodemographic data, anthropometric variables, and vitamin D concentration, defined as 25 (OH) D concentrations, were acquired from medical records. Data regarding health beliefs and HRQoL were obtained through structured questionnaire.</p><p><strong>Results: </strong>The mean 25(OH)D concentration was 29.6 ± 10.9 ng/mL and the overall prevalence of VDI was MetS was 54.9%. There was no significant difference in the prevalence of MetS between the VDI and sufficiency groups. Multivariate analysis revealed that the factors associated with VDI prevalence were female sex, age < 65 years, college and above education attainment, high LDL concentration, no alcohol use, and low scores on the emotional role item of HRQoL.</p><p><strong>Conclusions: </strong>VDI was not significantly associated with MetS prevalence or HBM constructs. However, key risk factors for VDI should be integrated into targeted health initiatives to address modifiable risk factors and improve vitamin D status.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"35 1","pages":"122-131"},"PeriodicalIF":1.6,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12823249/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146017100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Establishment and validation of a machine learning model to stratify malnutrition risk in hospitalized older patients with chronic heart failure. 老年慢性心力衰竭住院患者营养不良风险分层的机器学习模型的建立与验证
IF 1.6 4区 医学
Asia Pacific journal of clinical nutrition Pub Date : 2026-02-01 DOI: 10.6133/apjcn.202602_35(1).0014
Qiuhong Sun, Jing Che
{"title":"Establishment and validation of a machine learning model to stratify malnutrition risk in hospitalized older patients with chronic heart failure.","authors":"Qiuhong Sun, Jing Che","doi":"10.6133/apjcn.202602_35(1).0014","DOIUrl":"10.6133/apjcn.202602_35(1).0014","url":null,"abstract":"<p><strong>Background and objectives: </strong>Malnutrition among older hospitalized adults with chronic heart failure (CHF) is associated with adverse clinical outcomes, yet reliable early risk stratification tools remain lacking. This study aimed to develop and validate a machine learning (ML) model for malnutrition risk stratification in this population.</p><p><strong>Methods and study design: </strong>Malnutrition among older hospitalized adults with chronic heart failure (CHF) is associated with adverse clinical outcomes, yet reliable early risk stratification tools remain lacking. This study aimed to develop and validate a machine learning (ML) model for malnutrition risk stratification in this population.</p><p><strong>Results: </strong>Malnutrition prevalence was 44.1% (348/790). In the internal testing, CatBoost (CAT) achieved superior performance with an AUC of 0.901 (95% confidence interval [CI]: 0.858-0.943), accuracy of 0.840, recall of 0.753, and the lowest Brier score of 0.113. This model demonstrated strong calibration, clinical utility, and the highest composite score (62/64). External validation confirmed CAT's generalizability (AUC: 0.916, 95% CI: 0.887-0.945). SHAP analysis identified body mass index (BMI), calf circumference, New York Heart Association (NYHA) classification, age, and diabetes as signifi-cant contributors to malnutrition risk.</p><p><strong>Conclusions: </strong>The CAT-based model effectively stratifies malnutrition risk in older hospitalized CHF patients, offering a tool for early intervention to improve outcomes. Further multicenter prospective studies are needed to validate its real-world applicability.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"35 1","pages":"143-157"},"PeriodicalIF":1.6,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12823253/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146017170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serum albumin and hypertension: The mediating roles of BMI, C-reactive protein and extracellular fluid. 血清白蛋白与高血压:BMI、c反应蛋白和细胞外液的中介作用。
IF 1.6 4区 医学
Asia Pacific journal of clinical nutrition Pub Date : 2026-02-01 DOI: 10.6133/apjcn.202602_35(1).0006
Yan Wang, Huaiyu Hao, Qiang Lu, Lei Zhang
{"title":"Serum albumin and hypertension: The mediating roles of BMI, C-reactive protein and extracellular fluid.","authors":"Yan Wang, Huaiyu Hao, Qiang Lu, Lei Zhang","doi":"10.6133/apjcn.202602_35(1).0006","DOIUrl":"10.6133/apjcn.202602_35(1).0006","url":null,"abstract":"<p><p>The relationship between serum albumin and hypertension has attracted much attention. We sought to further validate these findings and explore the underlying mediators.</p><p><strong>Methods and study design: </strong>This cross-sectional study utilized data from the National Health and Nutrition Examination Survey (NHANES 1999-2004), including 19,507 participants. Multivariable weighted logistic were employed to investigate the association of serum albumin with hypertension. The potential mediating role of body mass index (BMI), C-reactive protein (CRP), and extracellular fluid (ECF) was explored. Secondary analyses included subgroup analyses and restricted cubic spline (RCS).</p><p><strong>Results: </strong>Serum albumin per 1 g/L increase was associated with 10% lower hypertension prevalence (OR=0.90, 95%CI:0.89-0.91, p <0.001). This remained significant after full adjustment (including age, sex, race/ethnicity, education level, smoking status, drinking status, sodium in-take, potassium intake, fat intake, total saturated fatty acids [TSFA] intake, carbohydrate intake, protein in-take, energy intake, diabetes, coronary heart disease, creatinine, alanine aminotransferase [ALT], and NHANES cycle)(OR = 0.98, 95%CI: 0.96-1.00, p = 0.031). No evidence of non-linearity was observed in the RCS analysis (p for non-linearity = 0.708). BMI mediated 42.75% (95%CI: 38.19%-48.33%), CRP 12.24% (95%CI: 9.29%-15.43%), and ECF 4.05% (95%CI: 2.74%-5.43%) of the association (all p <0.001). Results were robust in sensitivity analyses.</p><p><strong>Conclusions: </strong>The serum albumin levels were negatively associated with the prevalence of hypertension. Mediation analyses demonstrated a significant mediating effect of BMI, CRP and ECF, suggesting that serum albumin might be related to hypertension, potentially mediated by BMI, ECF, and CRP.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"35 1","pages":"60-70"},"PeriodicalIF":1.6,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12823252/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146017217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Burden of cardiovascular disease in China attributable to unbalanced fatty acid intake from 1990 to 2050. 1990 - 2050年中国脂肪酸摄入不平衡引起的心血管疾病负担
IF 1.6 4区 医学
Asia Pacific journal of clinical nutrition Pub Date : 2026-02-01 DOI: 10.6133/apjcn.202602_35(1).0010
Xiangrong Liu, Xinshen Zhang, Lu Liu, Zhimeng Yu, Xin Qin, Yetong Ma, Xueyan Yang, Yinghua Liu
{"title":"Burden of cardiovascular disease in China attributable to unbalanced fatty acid intake from 1990 to 2050.","authors":"Xiangrong Liu, Xinshen Zhang, Lu Liu, Zhimeng Yu, Xin Qin, Yetong Ma, Xueyan Yang, Yinghua Liu","doi":"10.6133/apjcn.202602_35(1).0010","DOIUrl":"10.6133/apjcn.202602_35(1).0010","url":null,"abstract":"<p><strong>Background and objectives: </strong>This study aimed to analyze the trends in death and disability-adjusted life years (DALYs) due to cardiovascular disease (CVD) associated with unbalanced dietary fatty acid intake in China from 1990 to 2021, and to predict the disease burden levels up to 2050.</p><p><strong>Methods and study design: </strong>Using Global Burden of Disease 2021 data, we examined death and DALYs rates by age, sex, and risk fac-tors. Joinpoint regression assessed temporal trends. Decomposition analysis evaluated contributions of population growth, aging, and epidemiological transitions. Age-period-cohort (APC) modeling estimated cohort and period effects. Bayesian Age-Period-Cohort (BAPC) modeling projected future CVD burden.</p><p><strong>Results: </strong>Age-standardized death and DALYs rates for CVD attributable to low seafood n-3 polyunsaturated fatty acids (PUFAs) and high trans fatty acids declined, while those due to insufficient n-6 PUFAs intake increased. Despite fluctuations, overall CVD burden showed a downward trend. Burden was higher in males and older groups. Population growth drove the absolute increase in burden, while aging and epidemiological shifts had variable effects by risk factor. APC modeling revealed significant age, period, and cohort influences. BAPC projections indicate continued decline in CVD burden from fatty acid imbalances through 2050.</p><p><strong>Conclusions: </strong>The CVD burden linked to imbalanced fatty acid consumption demonstrated a general decline, with forecasts suggesting a continued decrease by 2050. Older adults and males were highlighted as priority populations for focused interventions. These results can inform the development of targeted prevention and control initiatives.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"35 1","pages":"99-110"},"PeriodicalIF":1.6,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12823254/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146017161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Causal roles of immune cells and plasma metabolites in esophageal cancer: A Mendelian randomization study with nutritional insights. 免疫细胞和血浆代谢物在食管癌中的因果作用:一项营养见解的孟德尔随机研究。
IF 1.6 4区 医学
Asia Pacific journal of clinical nutrition Pub Date : 2026-02-01 DOI: 10.6133/apjcn.202602_35(1).0007
Xiaoxiao Liu, Yuchen Wang, Yongze Dang, Xia Li, Shangyi Geng, Xinyu He, Hongbing Ma, Xixi Zhao
{"title":"Causal roles of immune cells and plasma metabolites in esophageal cancer: A Mendelian randomization study with nutritional insights.","authors":"Xiaoxiao Liu, Yuchen Wang, Yongze Dang, Xia Li, Shangyi Geng, Xinyu He, Hongbing Ma, Xixi Zhao","doi":"10.6133/apjcn.202602_35(1).0007","DOIUrl":"10.6133/apjcn.202602_35(1).0007","url":null,"abstract":"<p><strong>Background and objectives: </strong>Metabolites, as key mediators of nutrition-immune interactions, have attracted increasing interest in cancer research. However, the causal relationships between immune cells, plasma metabolites, and esophageal cancer, and their potential for guiding nutritional interventions remain unclear.</p><p><strong>Methods and study design: </strong>We conducted a two-sample Mendelian randomization analysis using the inverse-variance weighted method to evaluate the causal effects of immune cells and plasma metabolites on esophageal cancer. We explored potential intermediary pathways by investigating associations between im-mune cell traits and plasma metabolites relevant to esophageal cancer risk. To test the robustness of our find-ings, we also carried out sensitivity analyses.</p><p><strong>Results: </strong>We identified 19 immune cell phenotypes associated with esophageal cancer risk (8 protective, 11 risk factors). In addition, 22 plasma metabolites (including 5 ratios) were protective, while 26 metabolites (including 8 ratios) increased risk, highlighting potential targets for nutritional interventions. Our analysis identified four plasma metabolites that were associated with specific immune cell traits relevant to esophageal cancer risk. Sensitivity analyses confirmed the robustness of the findings, with no significant heterogeneity or pleiotropy observed.</p><p><strong>Conclusions: </strong>This study provides genetic evidence for potential causal associations among immune cells, plasma metabolites, and esophageal cancer, and identifies observed associations between immune cell traits and plasma metabolites. These findings provide a foundation for precision nutrition and support dietary modification as a promising strategy for prevention and adjunctive therapy.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"35 1","pages":"71-80"},"PeriodicalIF":1.6,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12823260/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146017159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chinese expert consensus on dietary nutrition prescriptions and exercise intervention for sarcopenia (2025). 中国肌肉减少症膳食营养处方与运动干预专家共识(2025)。
IF 1.6 4区 医学
Asia Pacific journal of clinical nutrition Pub Date : 2026-02-01 DOI: 10.6133/apjcn.202602_35(1).0001
Jianqin Sun, Jie Chen, Mei He
{"title":"Chinese expert consensus on dietary nutrition prescriptions and exercise intervention for sarcopenia (2025).","authors":"Jianqin Sun, Jie Chen, Mei He","doi":"10.6133/apjcn.202602_35(1).0001","DOIUrl":"10.6133/apjcn.202602_35(1).0001","url":null,"abstract":"<p><p>Sarcopenia, characterized by an age-associated decline in skeletal muscle mass and strength/function, is associated with multiple adverse clinical outcomes. Dietary nutrition and exercise interventions are effective ways to prevent and improve sarcopenia. Therefore, Huadong Hospital affiliated to Fudan University, Shanghai Elderly Nutrition and Health Quality Control Center, together with the Geriatric Nutrition Branch of China Nutrition Society convened experts from nutrition, geriatrics, sports medicine, rehabilitation medicine, traditional Chinese medicine and general practice medicine to jointly set up a working group to supplement and revise the 2015 edition of China Expert Consensus on Nutrition and Exercise Intervention for Sarcopenia based on evidence-based medicine evidence in the past ten years to form this consensus. The aim is to provide practical guidelines to prevent and treat the disease.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"35 1","pages":"1-11"},"PeriodicalIF":1.6,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12823250/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146017136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vitamin B12 and D status in long-term vegetarians: Impact of diet duration and subtypes in Beijing, China. 中国北京长期素食者的维生素B12和D状况:饮食持续时间和亚型的影响
IF 1.6 4区 医学
Asia Pacific journal of clinical nutrition Pub Date : 2026-02-01 DOI: 10.6133/apjcn.202602_35(1).0013
Yun Wang, Xiaowei Xin, Hui Zhang, Ying Jia, Zhiheng Liu, Zhijian Xu, Yehua Gan, Suyun Li
{"title":"Vitamin B12 and D status in long-term vegetarians: Impact of diet duration and subtypes in Beijing, China.","authors":"Yun Wang, Xiaowei Xin, Hui Zhang, Ying Jia, Zhiheng Liu, Zhijian Xu, Yehua Gan, Suyun Li","doi":"10.6133/apjcn.202602_35(1).0013","DOIUrl":"10.6133/apjcn.202602_35(1).0013","url":null,"abstract":"<p><strong>Background and objectives: </strong>This study aimed to evaluate vitamin B12 and D levels among long-term vegetarians and to assess the influence of their diet duration and diet subtypes on nutritional status in Beijing, China.</p><p><strong>Methods and study design: </strong>A cross-sectional analysis was conducted on 104 vegetarians (84 vegans, 20 lacto-ovo vegetarians). Serum vitamin B12 and D levels were measured, and demographic, dietary, and supplement use data were collected. Statistical analyses included ANOVA, Kruskal-Wallis tests, chi-square tests, and multivariate regressions.</p><p><strong>Results: </strong>The prevalence of vitamin B12 deficiency (<200 pg/mL) was 38.5%, with higher rates in vegans (44.1%) than lacto-ovo vegetarians (15.0%, p = 0.021). Vitamin D defi-ciency (<20 ng/mL) affected 84.6% of participants, worsening with longer diet duration (p <0.001), yet showed no significant difference between vegan and lacto-ovo subtypes (85.7% vs 80.0%, p = 0.524). Multivariate analysis revealed negative correlations between diet duration (6-10 years and >10 years) and vita-min B12 and D levels (p <0.05). Lacto-ovo vegetarians showed significantly higher vitamin B12 levels than vegans (p = 0.029), and supplement use improved both vitamins' status (p <0.05).</p><p><strong>Conclusions: </strong>This study reveals a dual challenge among Beijing long-term vegetarians: vitamin B12 deficiency was strongly associated with the degree of exclusion of animal products from the diet (veganism), while vitamin D deficiency was highly prevalent and worsened with longer diet duration. The near-universal vitamin D deficiency observed in this study suggests that, in the Beijing context, the risk may extend beyond dietary choice, potentially reflecting regional environmental factors; however, this requires confirmation through comparative studies with omnivores controls.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"35 1","pages":"132-142"},"PeriodicalIF":1.6,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12823248/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146017268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Weight management for overweight and obese adolescents: Current treatments. 超重和肥胖青少年的体重管理:目前的治疗方法。
IF 1.6 4区 医学
Asia Pacific journal of clinical nutrition Pub Date : 2025-12-01 DOI: 10.6133/apjcn.202512_34(6).0001
Liru Chen, Xingyu Zhu, Chengyu Liu
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