Danhua Liang, Xianrui Dou, Luona Wen, Yongqian Liang, Wei Zhang, Lan Liu, Ke Chen, Rongshao Tan
{"title":"Effects of oral low-protein energy supplements on nutritional status in maintenance hemodialysis patients with protein-energy wasting: a randomized controlled trial.","authors":"Danhua Liang, Xianrui Dou, Luona Wen, Yongqian Liang, Wei Zhang, Lan Liu, Ke Chen, Rongshao Tan","doi":"10.6133/apjcn.202506_34(3).0006","DOIUrl":"10.6133/apjcn.202506_34(3).0006","url":null,"abstract":"<p><strong>Background and objectives: </strong>Protein-energy wasting (PEW) is common among maintenance hemodialysis (MHD) patients and is strongly associated with mortality and adverse outcomes. This study aimed to assess the effects of low-protein energy supplements on the nutritional status of MHD patients with PEW.</p><p><strong>Methods and study design: </strong>We conducted a prospective randomized controlled trial in 68 MHD patients suffering from PEW. Patients randomized to the intervention group received dietary counseling along with daily low-protein supplements containing 212 kcal of energy and 2.4 g of protein every day for 3 months. The control group received dietary counseling only. Dietary data, nutritional assessments, anthropometric measurements, bioelectrical impedance analysis and blood analysis were collected at baseline and after three months from both groups.</p><p><strong>Results: </strong>Fifty-nine MHD patients completed the study. Patients in the intervention group showed an increase in energy intakes (p < 0.001). A significant decrease in the Malnutrition Inflammation Score (MIS) (p < 0.001) and Nutrition Risk Screening 2002 (p< 0.001) were found in the intervention group compared with the control group. Moreover, significant improvements in mid-upper arm circumference (p < 0.001), mid-arm muscle circumference (p < 0.001), albumin (p = 0.003), and prealbumin (p = 0.033) were observed in the intervention group compared with the control group.</p><p><strong>Conclusions: </strong>The combination of oral low-protein supplements and dietary counseling for three months was more effective than dietary counseling alone in terms of improving the nutritional status of MHD patients with PEW.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"34 3","pages":"316-324"},"PeriodicalIF":1.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12126292/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144149060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Meidi Wang, Qianqian Li, Jing Wu, Mingyao Xu, Jia R Yue, Weiwei W Cui
{"title":"Global trends and hotspots in nutritional risk screening, assessment, and diagnosis: A bibliometric and visual analysis (1991-2024).","authors":"Meidi Wang, Qianqian Li, Jing Wu, Mingyao Xu, Jia R Yue, Weiwei W Cui","doi":"10.6133/apjcn.202506_34(3).0002","DOIUrl":"10.6133/apjcn.202506_34(3).0002","url":null,"abstract":"<p><strong>Background and objectives: </strong>Nutrition is important in promoting health and preventing disease, while malnutrition can exacerbate disease symptoms and lead to adverse clinical outcomes in patients. The process of nutritional diagnosis and treatment includes nutritional risk screening, nutritional assessment, and nutritional therapy. This study aims to understand the number of publications, cooperation of research subjects, progress of research content, and research hotspots of nutritional risk screening and assessment, and then identify the future trends and directions of global nutritional screening.</p><p><strong>Methods and study design: </strong>Articles on nutritional risk screening, nutritional assessment and application of nutritional diagnostic tools were identified from the Web of Science and the collected data were analysed using bibliometrics and information visualisa-tion with the help of CiteSpace software. A total of 10632 articles published between 1991 and 2024 were selected.</p><p><strong>Results: </strong>The country with the highest number of articles was the United States; two institutions, the University of São Paulo and the Karolinska Institutet, had higher centrality and number of articles. Keyword emergent analysis revealed that global leadership initiatives on malnutrition, diagnosis, criteria, myasthenia gravis, and clinical nutrition were the five emergent terms that lasted until 2024 and were the most popular hot topics among experts and scholars.</p><p><strong>Conclusions: </strong>We describe the characteristics of the development of nutritional risk screening and assessment studies and their trends. Currently, there is not a close collaboration between institutions and authors in the research process, while the field is trending towards more specific research and a greater focus on the disease progression in patients.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"34 3","pages":"271-281"},"PeriodicalIF":1.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12126299/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144149066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lauren P Manning, Caroline J Tuck, Jessica R Biesiekierski
{"title":"Predicting response to the low FODMAP diet in irritable bowel syndrome: Current evidence and clinical considerations.","authors":"Lauren P Manning, Caroline J Tuck, Jessica R Biesiekierski","doi":"10.6133/apjcn.202506_34(3).0012","DOIUrl":"10.6133/apjcn.202506_34(3).0012","url":null,"abstract":"<p><strong>Background and objectives: </strong>The low fermentable oligo-, di-, mono-saccharides and polyols (FODMAP) diet is an effective dietary intervention for irritable bowel syndrome (IBS), yet up to 50% of patients fail to re-spond adequately. Identifying reliable predictors of response could optimize treatment selection and improve treatment outcomes while avoiding unnecessary dietary restrictions. This narrative review examines current evidence for predictors of response to the low FODMAP diet and highlights gaps in knowledge that must be addressed to develop clinically useful indicators for routine practice.</p><p><strong>Methods and study design: </strong>We re-viewed the literature on the low FODMAP diet, and studies investigating factors that may predict treatment response, including clinical, diagnostic, biological, biochemical, and microbial markers.</p><p><strong>Results: </strong>Several po-tential predictors to the low FODMAP diet have emerged, including baseline symptom severity, psychological factors (particularly depression), hydrogen breath test results, volatile organic compounds in fecal samples, and specific gut microbiota profiles. Clinical and psychological measures show the most immediate potential for implementation due to accessibility and established measurement tools. Biological markers, including breath testing, metabolomics, and microbiome analysis, show promise but require further validation in larger, diverse populations and standardization of methodologies.</p><p><strong>Conclusions: </strong>Despite promising research, signifi-cant gaps remain in developing reliable, accessible predictors of response to the low FODMAP diet. Future research should focus on validating simple clinical tools that combine symptom profiles with psychological assessment to guide treatment decisions. A personalized approach to dietary management of IBS based on reliable response predictors would optimize clinical outcomes while minimizing unnecessary dietary restriction and healthcare resource utilization.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"34 3","pages":"373-385"},"PeriodicalIF":1.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12126294/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144149071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Junren Kang, Yuanyuan Bao, Ji Fu, Hailong Li, Kang Yu
{"title":"Bundled behavioural strategies for long-term weight maintenance in Chinese patients with overweight or obesity.","authors":"Junren Kang, Yuanyuan Bao, Ji Fu, Hailong Li, Kang Yu","doi":"10.6133/apjcn.202506_34(3).0005","DOIUrl":"10.6133/apjcn.202506_34(3).0005","url":null,"abstract":"<p><strong>Background and objectives: </strong>Behavioural strategies can promote adherence to intensive lifestyle treatments for obesity. This study aimed to explore effective behavioural strategies for weight maintenance in Chinese patients with overweight or obesity.</p><p><strong>Methods and study design: </strong>Retrospective analysis of weight mainte-nance data was conducted. Patients with overweight or obesity, who had received a 3-month weight loss and behavioural intervention, were asked to complete questionnaires to monitor compliance with behavioural strategies after the weight loss. They continued to follow a daily calorie restriction for 12 months to maintain their weight. The primary outcome was to evaluate the association between a total weight loss (TWL) of more than 5% and compliance with behavioural strategies during the 6-month weight maintenance phase.</p><p><strong>Results: </strong>A total of 131 patients completed the questionnaire. The top three easy-to-perform behaviours were eating vegetables and protein first and carbohydrates later, self-weighing each day and having regular eating times. Of 131 patients, 61 (46.5%) and 42 (32.1%) were followed up for 6 months and 12 months respectively. Reducing high-fat food intake (p = 0.002) and eating an average frequency of 5 times a day (p = 0.034) were associated with a TWL of more than 5% during 6 months weight maintenance. Reducing high-fat food intake was associated with a TWL of more than 5% during 12 months weight maintenance (p = 0.029).</p><p><strong>Conclusions: </strong>Chinese patients with overweight or obesity who experienced a TWL of more than 5% were more likely to reduce high-fat food intake during long-term weight maintenance.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"34 3","pages":"308-315"},"PeriodicalIF":1.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12126304/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144149056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Commentary: Underweight in adults: Time for ethnic-specific criteria?","authors":"Hetal Rathod, L Naga Rajeev","doi":"10.6133/apjcn.202506_34(3).0022","DOIUrl":"10.6133/apjcn.202506_34(3).0022","url":null,"abstract":"<p><p>The classification for underweight adults, defined as a body mass index (BMI; <18.5 kg/m²) by the World Health Organization (WHO), has been consistent globally with respect to populations. Although the WHO has recognized that body composition and health risks differ according to ethnicity by offering adjusted BMI cut-offs for overweight and obesity (23-24.9 kg/m² for overweight and ≥25 kg/m² for obesity) in Asian-populations, the underweight threshold has strangely not been modified. Because there is evidence of unique physiological and metabolic profiles of Asian populations the applicability of this uniformity to Asian populations remains as an important question.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"34 3","pages":"486"},"PeriodicalIF":1.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12126285/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144149057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cow's milk protein allergy: A comprehensive review of epidemiology, pathogenesis, clinical manifestations, diagnostics, and management strategies.","authors":"Li Hao, Songqing Wang, Wei Ji","doi":"10.6133/apjcn.202506_34(3).0004","DOIUrl":"10.6133/apjcn.202506_34(3).0004","url":null,"abstract":"<p><p>Cow's milk protein allergy is an adverse immune reaction to proteins found in cow's milk, primarily casein and whey, affecting artificially fed, breastfed and mixed-fed infants. The immunological mechanisms involved lead to diverse clinical presentations, most commonly affecting the digestive, respiratory, and integumentary systems. Diagnosis relies primarily on clinical evaluation due to the absence of specific diagnostic tests, making accurate identification crucial to prevent misdiagnosis or underdiagnosis. Treatment requires strict avoidance of cow's milk proteins in the diets of both children and breastfeeding mothers, with close monitoring of nutritional status during long-term management. Recent advancements in treatment, including the use of probiotics, provide new options for improving clinical outcomes. This narrative review aims to provide clinicians with evidence to standardise diagnosis and treatment, improve food allergy management by non-allergy specialists and develop accurate feeding recommendations.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"34 3","pages":"298-307"},"PeriodicalIF":1.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12126303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144149058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Factors influencing thyroid volume and comparative analysis of thyroid volume correction methods in children aged 8-10 years in Gansu, China.","authors":"Xiulan Fei, Yanling Wang, Aiwei He, Xiaonan Zhu, Yugui Dou, Wei Sun","doi":"10.6133/apjcn.202506_34(3).0020","DOIUrl":"10.6133/apjcn.202506_34(3).0020","url":null,"abstract":"<p><strong>Background and objectives: </strong>This study aimed to analyze the relationship between thyroid volume (TVOL) and physical development of children, and explore the suitable TVOL correction methods.</p><p><strong>Methods and study design: </strong>1500 children aged 8-10 years from Gansu province northwest China were selected. The height (H), weight (W), urine iodine of children was measured and their thyroid was examined by ultrasound. Body mass index (BMI), body surface area (BSA) and TVOL were calculated (BSA calculated by three formulas). The relationship between TVOL and age, sex, physical development was analyzed. The applicability of TVOL correction methods including BMI corrected volume (BMIV), BSA corrected volume (BSAV), weight and height corrected volume indicator (WHVI) and height corrected volume indicator (HVI) were compared.</p><p><strong>Results: </strong>Median urinary iodine concentrations of children aged 8, 9, 10 years were 166.6 μg/L, 167.2 μg/L and 178.8 μg/L respectively. The rate of iodine deficiency was 20.3%, the rate of thyroid goiter was 3.2%. Physical development indexes (height, weight, BMI and BSA) and TVOL increased with age. Also, physical development indexes (height, weight, BMI and BSA) of boys were higher than girls (p <0.05). Only BSAV1 had no correlation with all physical development indexes (p >0.05). The TVOL P97 (97th percentile) of children aged 8, 9, 10 years were 4.4 ml, 4.9 ml, 6.5 ml, the values were 4.6 mL, 4.7 mL, 5.9 mL after BSAV1 corrected. The difference between TVOL and BSAV1 ranges from -0.37% to 0.36%.</p><p><strong>Conclusions: </strong>The thyroid volume is not only affected by age, but it is also affected by physical development. Thyroid goiter should be assessed based on age and physical development. The formula BSAV1=TVOL/ (W0.425×H0.725×71.84×10-4) was a suitable TVOL correction method.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"34 3","pages":"469-476"},"PeriodicalIF":1.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12126286/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144149062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Physical activity, eating habits and weight loss outcomes two years following sleeve gastrectomy in women.","authors":"Ahlam Alhajri","doi":"10.6133/apjcn.202506_34(3).0011","DOIUrl":"10.6133/apjcn.202506_34(3).0011","url":null,"abstract":"<p><strong>Background and objectives: </strong>Sleeve gastrectomy (SG) is a commonly utilized surgical procedure for managing weight and patients must adopt healthy lifestyle practices and dietary modifications to sustain weight loss and prevent relapse. This study aims to evaluate the dietary habits, levels of physical activity, and weight outcomes among Saudi women post-gastric sleeve surgery.</p><p><strong>Methods and study design: </strong>This study involved 352 female participants aged 20 to 50, who had undergone gastric sleeve surgery. The Bariatric Patients As-sociation, Bariatric World and Patients Forum were also used and contacted via phone. Surveys were used to ascertain their physical activity levels and dietary behaviors; a food frequency questionnaire (FFQ) was also utilized and each participant's BMI was calculated.</p><p><strong>Results: </strong>The study involved 352 women, of whom the highest proportion was in the 40-50 age group. Prior to the surgery, nearly all of the participants (98.9%) were diagnosed as having obesity or morbid obesity, which significantly decreased following the surgery. According to the participants, the primary reason for undergoing the surgery was failed dietary regimens (26.4%). A considerable portion of participants continued consuming dietary supplements post-surgery (35.59%) and frequently consumed juices and sweets. Most of the participants did not meet the WHO rec-ommendations for regular physical activity. Correlation analysis revealed a significant relationship between BMI and the consumption of healthy foods post-surgery.</p><p><strong>Conclusions: </strong>The study identified concerning life-style habits among the participants, underscoring the importance of maintaining a healthy diet and engaging in regular physical activity to optimize the long-term benefits of weight loss surgery and enhance overall well-being.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"34 3","pages":"363-372"},"PeriodicalIF":1.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12126296/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144149070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association of meal component combinations with nutrient adequacy in Japanese adults.","authors":"Honoka Murahata, Kotone Nakamura, Eri Imai","doi":"10.6133/apjcn.202506_34(3).0013","DOIUrl":"10.6133/apjcn.202506_34(3).0013","url":null,"abstract":"<p><strong>Background and objectives: </strong>Consuming a diet that ensures adequate nutrient intake is essential to address all forms of malnutrition. In Japan, a meal combining staple food, main dish, and side dish is considered a balanced diet. This study was conducted to investigate the frequency of meals combining staple food, main dish, and side dish associated with nutrient adequacy.</p><p><strong>Methods and study design: </strong>This cross-sectional study included 6,264 adults. All data were obtained from the 2015 Health and Nutrition Survey in Shiga prefecture. Staple food, main dish, and side dish were each defined as a dish with primary ingredients of ≥50 g. Regarding the frequency, participants were divided into ≥2 and <2 times/d groups. The nutrient adequacy evaluated using the Dietary Reference Intakes for Japanese 2020 (DRIs-J) score is based on the reference values provided in the DRIs-J. The t-test was used to evaluate nutrient adequacy between the 2 groups.</p><p><strong>Results: </strong>Of the total participants, only 1,423 (22.7%) were classified into the ≥2 times/d group, and they had significantly higher DRIs-J scores than participants in the <2 times/d group (p < 0.001). The adequacy percentage of all nutrients except saturated fatty acid, particularly dietary fiber and most micronutrients, was > 1.5-fold higher in the ≥2 times/d group than in the <2 times/d group (p < 0.001).</p><p><strong>Conclusions: </strong>This study provides important information that meals combining staple food, main dish, and side dish at least twice a day is effective in maintaining a diet with high nutrient adequacy.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"34 3","pages":"386-396"},"PeriodicalIF":1.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12126300/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144149054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Role of TyG, TyG-BMI and METS-IR in osteoporosis risk among older men: a retrospective cohort study.","authors":"Jing Zeng, Ting Li, Zimo Pan, Qianqian Liu, Jinfu He, Xiaoyan Cai, Meiliang Gong, Xinli Deng, Yanping Gong, Nan Li, Chunlin Li","doi":"10.6133/apjcn.202506_34(3).0021","DOIUrl":"10.6133/apjcn.202506_34(3).0021","url":null,"abstract":"<p><strong>Background and objectives: </strong>Obese and diabetic individuals tend to have insulin resistance, but are less like-ly to develop osteoporosis. The association of triglyceride-glucose (TyG) related indices with osteoporosis remains controversial, and longitudinal evidence exploring the male osteoporosis (MOP) is limited. This study aims to examine TyG, TyG-body mass index (TyG-BMI) and the metabolic score for insulin resistance (METS-IR) with osteoporosis risk among older men.</p><p><strong>Methods and study design: </strong>A cohort study based on 1622 middle-aged and older men in 2015 was conducted, and followed up until 2022. Participants with oste-oporosis and admittedly secondary risk factors were excluded. TyG, TyG-BMI, METS-IR and corresponding quantiles were calculated. Cox proportional hazard regression models were used to assess the hazard ratios (HRs) and 95% confidence interval (CI). Receiver operating characteristic (ROC) curve was applied to estimate their performance in osteoporosis screening.</p><p><strong>Results: </strong>72 of 1622 participants were newly developed OP during the 9317 person-years. The adjusted HRs of TyG, TyG-BMI, and METS-IR for MOP were 0.573 (95%CI 0.336-0.976), 0.991 (95%CI 0.984-0.999) and 0.929 (95%CI 0.892-0.968), respectively, and pre-sented at linear dose-response relationships. Subgroup analysis showed that the estimated benefit for MOP incidence was consistent among participants aged more than 70 years and related to BMI and eating mount of milk, fresh fruit and vegetables. No difference was found in the area under ROC curve for screening osteo-porosis, ranging from 0.585 to 0.617.</p><p><strong>Conclusions: </strong>TyG and relevant indices were associated with the inci-dence of osteoporosis in the senile men, and the relationship was thought to correlate with BMI and nutritional behaviors.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"34 3","pages":"477-485"},"PeriodicalIF":1.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12126297/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144149073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}