Asia Pacific journal of clinical nutrition最新文献

{"title":"Circulating vitamin D concentrations and the risk of urticaria: A bidirectional two-sample Mendelian randomization study.","authors":"Hai-Xia Chai, Feng Wang, Hui Liu, Yu-Qing Xie, Zhi-Heng Zhou","doi":"10.6133/apjcn.202510_34(5).0004","DOIUrl":"10.6133/apjcn.202510_34(5).0004","url":null,"abstract":"<p><strong>Background and objectives: </strong>Vitamin D deficiency has been linked to urticaria, but causality remains uncer-tain. We used Mendelian randomization (MR) to investigate potential causal effects of vitamin D and its me-tabolites on urticaria risk.</p><p><strong>Methods and study design: </strong>Summary statistics from genome-wide association studies (GWAS) of total 25-hydroxyvitamin D [25(OH)D] (n=120,618), 25-hydroxyvitamin D3 [25(OH)D3] (n=40,562), and C3-epimer-25-hydroxyvitamin D3 [C3-epi-25(OH)D3] (n=40,562) in Europeans were used, along with data on urticaria and its subtypes from FinnGen consortium (R10 release). For validation, we performed additional MR analyses using a larger dataset that meta-analyzed data from the UK Biobank and GWAS results from the SUNLIGHT consortium (n=496,946) as exposure variables. We performed compre-hensive sensitivity analyses, including heterogeneity tests, pleiotropy assessments, and leave-one-out analyses to evaluate result robustness. Statistical power calculations were conducted to validate the reliability of our findings.</p><p><strong>Results: </strong>MR analysis revealed a causal protective effect of higher total 25(OH)D levels on urticaria risk [odds ratio (OR) = 0.81, 95% confidence interval (CI):0.69-0.95, p =0.008, statistical power = 81.1%]. Similar causal effects were observed for 25(OH)D3 levels (OR = 0.85, 95% CI: 0.74-0.98, p = 0.023, statistical power = 67.4%).These findings were validated in the replication cohort using serum 25(OH)D measurements (OR = 0.69, 95%CI: 0.56-0.85, p = 0.001, statistical power = 96.1%). Sensitivity analyses showed no significant heterogeneity or pleiotropy. Reverse MR analysis found no evidence that genetic risk of urticaria affects vitamin D levels, suggesting a potentially unidirectional causal relationship.</p><p><strong>Conclusions: </strong>This study provides the first genetic evidence that higher vitamin D levels may reduce urticaria risk, offering a new theoretical basis for urticaria prevention and treatment strategies.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"34 5","pages":"740-749"},"PeriodicalIF":1.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490950/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145211517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modulation of gene expression by traditional Asian antidiabetic nutraceuticals: A review of potential effects.","authors":"Katrin Roosita, Karina Rahmadia Ekawidyani, Rosyanne Kushargina, Fathimah, Mohamad Rafi, Uus Saepuloh","doi":"10.6133/apjcn.202510_34(5).0006","DOIUrl":"10.6133/apjcn.202510_34(5).0006","url":null,"abstract":"<p><strong>Background and objectives: </strong>Type 2 diabetes mellitus (T2DM) has emerged as a significant global public health concern. Multiple studies have shown that traditional nutraceuticals are potential to treat T2DM and its complications. This review will explore traditional nutraceuticals with antidiabetic properties with a focus on traditional Asian nutraceuticals and their antioxidant effects on gene expression associated to T2DM.</p><p><strong>Methods and study design: </strong>Literature searching was conducted in Pubmed, Scopus, and Science Direct using the keywords \"nutraceutical\", \"antidiabetic\", \"insulin resistance\", \"Diabetes Mellitus\", \"herbal medicine\", \"mechanism\", \"pathway\", \"traditional food\", \"functional food\", \"antioxidant\", \"clinical\", \"preclinical\", \"animal studies\", and \"Asian\" combined with Boolean operators \"OR\".</p><p><strong>Results: </strong>Nutraceuticals sourced from traditional Indonesian herbal beverages, including Galohgor, Bir Pletok, and Wedang Uwuh, have shown potential efficacy in reducing hyperglycemia, oxidative stress, and obesity in T2DM. Furthermore, multiple Asian plants and their bioactive compounds, such as curcumin, kaempferol, cinnamon, saponin, quercetin, myricetin, anthocyanin, terpenoid, alkaloid, and gallic acid, have been shown to beneficially influence glucose ho-meostasis, insulin sensitivity, and problems associated with diabetes. Moreover, bioactive compounds of these traditional nutraceuticals have been proven in modulating gene expression associated with β-cell function, insulin signaling pathway, and antioxidant activity, which may offer a new therapeutic target.</p><p><strong>Conclusions: </strong>This review highlights the increasing scientific evidence on the role of traditional nutraceuticals for the prevention and management of diabetes mellitus, presenting promising alternatives to standard pharmacologi-cal therapy. Nonetheless, double-blind randomized clinical trials are required to validate these antidiabetic effects.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"34 5","pages":"759-782"},"PeriodicalIF":1.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490953/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145211520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low dietary quality in patients with COPD and the association with disease severity: A cross-sectional study.","authors":"Mingxin Li, Yulian Sun, Luyao Li, Liangjie Zhao, Quanguo Li, Xiaoqi Zhang, Yang Yang, Aiguo Ma, Jing Cai","doi":"10.6133/apjcn.202510_34(5).0009","DOIUrl":"10.6133/apjcn.202510_34(5).0009","url":null,"abstract":"<p><strong>Background and objectives: </strong>Dietary nutrition plays an essential role in the progression of chronic obstruc-tive pulmonary disease (COPD). This study aimed to use Chinese Healthy Eating Index (CHEI) to evaluate dietary quality in COPD patients and investigate the relationship between dietary quality and COPD disease severity.</p><p><strong>Methods and study design: </strong>A total of 525 COPD inpatients were collected from December 1st, 2022, to December 1st, 2023. The dietary intake was collected through food frequency questionnaires (FFQ), and diet quality was assessed by the CHEI. Modified Medical Research Council Dyspnea Scale (mMRC), the COPD assessment test (CAT), and Global Initiative for Obstructive Lung Disease (GOLD) stage were used to assess disease severity. Multivariable logistic regression was used to analyze the association between the total CHEI score, and its component scores and COPD disease severity.</p><p><strong>Results: </strong>The CHEI score with COPD pa-tients is 56.75±8.89. The CAT score of the low CHEI group was significantly higher than that of the high CHEI group (p <0.05). Ordinal logistic regression analysis indicated that the group with higher CHEI total scores was significantly associated with the low grade of mMRC (OR: 0.982, 95%CI: 0.964, 1.000, p <0.05). And the higher intake of tubers, whole grains and mixed beans, and fish and seafood were all associated with lower mMRC grades (p <0.05).</p><p><strong>Conclusions: </strong>COPD patients have poor dietary quality. High CHEI scores were associated with the low mMRC grades. Patients with COPD should be encouraged to maintain a good quality diet to reduce the risk of disease exacerbation.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"34 5","pages":"810-820"},"PeriodicalIF":1.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490952/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145211497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic and application guidelines for malnutrition in adult patients (2025 edition).","authors":"","doi":"10.6133/apjcn.202510_34(5).0001","DOIUrl":"10.6133/apjcn.202510_34(5).0001","url":null,"abstract":"<p><p>Malnutrition is a crucial factor affecting the prognosis of various diseases, especially among elderly, surgical and critically ill patients. With the implementation of Diagnosis Related Groups (DRGs) and Diagnosis-Intervention Packet (DIP) in China, accurate diagnosis and treatment of malnutrition is essential for enhancing clinical decision-making and patient prognosis. These guidelines were developed by multidisciplinary experts through a systematic review of evidence-based medical literature. They adopt the new international standard for malnutrition diagnosis from the Global Leadership Initiative on Malnutrition (GLIM) proposed by the Global Nutrition Organization and categorize evidence levels, providing recommendations tailored to the Chinese population's data and characteristics. The guidelines cover the entire process of malnutrition diagnosis in adult patients, including definition, epidemiology, nutrition risk screening, multi-level nutrition assessment, and diagnostic procedures. They also propose individualized diagnostic strategies for specific patient groups, such as obese or critically ill patients, and establish a standardized process for malnutrition diagnosis. At last, the guidelines form 27 questions, 38 recommendations, in order to improve the practical capac-ity of malnutrition diagnosis in China.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"34 5","pages":"699-723"},"PeriodicalIF":1.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490954/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145211527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of 'FenuflakesTM' on 24-hour glycemic variability in adults with type 2 diabetes: A randomized crossover continuous glucose monitoring study.","authors":"Pallavi Onkar Deshpande, Chinmaya Adwait Gokhale, Sunil Bhaskaran, Rajagopal Gayathri, Kuzhadaivelu Abirami, Ranjit Mohan Anjana, Kamala Krishnaswamy, Viswanathan Mohan, Vasudevan Sudha","doi":"10.6133/apjcn.202510_34(5).0003","DOIUrl":"10.6133/apjcn.202510_34(5).0003","url":null,"abstract":"<p><strong>Background and objectives: </strong>Evidence suggests that bioactive components present in plant foods have beneficial effects. Fenugreek is commonly used in Indian culinary practices and can help to keep blood sugar levels under control. The objective of this study was to assess the efficacy of defatted fenugreek seed flakes (FenuflakesTM) on the 24-hour glycaemic response (Incremental Area Under the Curve, iAUC), variability (Mean Amplitude Glycaemic Excursion assessed by Continuous Glucose Monitoring system) in participants with type 2 diabetes.</p><p><strong>Methods and study design: </strong>Twenty-one type 2 diabetes participants, aged 42 to 50 years, were provided with 5-day cyclic iso-caloric diets for 14 days without (control diet) and with 30 g of FenuflakesTM (test diet) in a randomized crossover trial. The Abbott Pro sensor recorded interstitial glucose concentration every 15 minutes consecutively for 14 days in the participants. Additionally, fasting plasma glucose and glycated hemoglobin (HbA1c) were assessed at the baseline and end of the study.</p><p><strong>Results: </strong>15 out of 21 participants completed the randomized control and test diet feeding periods as per protocol. There was a significant reduction in 24-hour iAUC (p=0.02) and mean amplitude glycemic excursions (p=0.006) in the test diet as compared to control diet. Furthermore, within the test diet, there was a significant reduction in fasting plasma glucose and HbA1c (p<0.05) at the end of the 14-day intervention period.</p><p><strong>Conclusions: </strong>The results suggest that the inclusion of FenuflakesTM, into regular dietary practices may effectively reduce glucose levels and enhance glycemic control in Asian Indian adults with type 2 diabetes.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"34 5","pages":"730-739"},"PeriodicalIF":1.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490948/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145211477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Shellfish-based dietary patterns and cognition in the Chinese senior population: A cross-sectional study in Qingdao, China.","authors":"Jingkai Zhang, Xiaolong Li, Tong Zhou, Ziyu Lu, Jie Xu, Haiping Duan","doi":"10.6133/apjcn.202510_34(5).0013","DOIUrl":"10.6133/apjcn.202510_34(5).0013","url":null,"abstract":"<p><strong>Background and objectives: </strong>This study aims to investigate the association between dietary patterns and cognitive function among older adults with lower educational backgrounds living in China.</p><p><strong>Methods and study design: </strong>We analyzed data from the 2018 Health Survey of individuals aged over 50 in Chengyang, Qingdao, China. Questionnaires were used to collect information on the behaviors and lifestyles of the elderly. The Montreal Cognitive Assessment (MoCA) was administered to evaluate cognition, with a total score of less than 19 indicating cognitive impairment for participants with low educational attainment. Using Principal Component Analysis, we identified three dietary patterns: Shellfish, Fruit, and Red Meat. Cross-sectional data regarding dietary intake, cognition, and demographics from 964 participants was analyzed using multivariate regression models to explore the relationship between dietary patterns and cognitive function.</p><p><strong>Results: </strong>Our findings indicated that the 'Shellfish-based' dietary pattern (\"Shellfish\" DP) was significantly associated with cognitive function in both the third quartile (Q3: Odds Ratio = 0.58, 95% CI: 0.36-0.93, p <0.05) and the fourth quartile (Q4: OR = 0.54, 95% CI: 0.33-0.87, p <0.05). Furthermore, stratified analysis based on specific covariates revealed that significant results among individuals with a BMI of less than 25 kg/m² (OR = 0.57, 95% CI: 0.33-0.99, p <0.05). No significant interaction effects were observed between shellfish dietary intake and various subgroups (all interaction p >0.05).</p><p><strong>Conclusions: </strong>Our research demonstrates that \"Shell-fish\" DP is negatively correlated with cognitive decline among the elderly population. This correlation is particularly significant in individuals with BMI < 25kg/m2, as well as among women and under the age of 65. However, no interaction was observed between the shellfish DP and the various subgroups. These findings can effectively guide older adults in optimizing their dietary structures, thereby safeguarding their cognition.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"34 5","pages":"852-861"},"PeriodicalIF":1.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490944/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145211458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric evaluation of the Screening Tool for Feeding Problems (STEP) in Saudi children with developmental disabilities aged 4-18 years.","authors":"Walaa Abdullah Mumena, Eradah Omar Hamad, Hebah Alawi Kutbi","doi":"10.6133/apjcn.202510_34(5).0010","DOIUrl":"10.6133/apjcn.202510_34(5).0010","url":null,"abstract":"<p><strong>Background and objectives: </strong>Children with developmental disabilities commonly experience feeding problems; however, tools to assess the nature and extent of these difficulties are not available in Arabic. This study aims to validate the Arabic version of the Screening Tool for Feeding Problems (STEP) and evaluate its factorial structure in children with developmental disabilities.</p><p><strong>Methods and study design: </strong>This cross-sectional study involved 167 children with developmental disabilities, recruited from nine disability centers and schools in Madinah, Saudi Arabia. Data were collected from caregivers using a paper version of the Arabic version of STEP, which was sent home with the child along with a consent form for signature. The English-to-Arabic translation of the tool was conducted by a bilingual professional using the forward-backward translation method.</p><p><strong>Results: </strong>Confirmatory factor analysis was performed to evaluate the factorial structure of the Arabic version of STEP using two models. Model 1 included all 23 items; Model 2 excluded six items with low factor loadings, resulting in a 17-item version. Model 2 demonstrated improved goodness of fit indices, supporting a modified five-factor structure. Reliability analysis showed acceptable internal reliability for the total scale in both models, with Cronbach's alpha of 0.80 and McDonald's omega of 0.79 for Model 1, and alpha of 0.83 and omega of 0.82 for Model 2. Internal consistency for individual factors ranged from 0.31 to 0.70.</p><p><strong>Conclusions: </strong>The Arabic version of STEP demonstrates satisfactory psychometric properties and appears to be a valid and reliable tool for screening feeding difficulties in children with developmental disabilities in the Saudi Arabian context.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"34 5","pages":"821-828"},"PeriodicalIF":1.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490949/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145211378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Causal association of dietary intake habits and telomere lengths: A Mendelian randomization study.","authors":"Jiahe Chen, Zhaoshuo Liu, Yang Nan, Haotian Liu, Ziqi Ren, Jianli Liu, Dan Liu, Ruiquan Qi","doi":"10.6133/apjcn.202510_34(5).0007","DOIUrl":"10.6133/apjcn.202510_34(5).0007","url":null,"abstract":"<p><strong>Background and objectives: </strong>Healthy diets are crucial in disease prevention and balanced diets can slow te-lomere shortening. Currently, it is still unclear which dietary factors are causally related to telomere length.</p><p><strong>Methods and study design: </strong>The inverse variance weighted, Mendelian Randomization-Egger, weighted median, simple mode, and weighted mode methods were used. Additionally, heterogeneity, pleiotropy, MR-PRESSO and leave-one-out tests were conducted to ensure accuracy. Outcomes included granulocyte, lym-phocyte, naive T-cell, memory T-cell, B-cell, and natural killer-cell telomere lengths. Exposures included alcohol intake frequency, alcoholic drinks per week, average weekly beer plus cider intake, average weekly red wine intake, intake of beef, bread, cereal, coffee, cooked vegetable, dried fruit, fresh fruit, lamb/mutton, non-oily fish, oily fish, pork, processed meat, salad/raw vegetable, tea and water.</p><p><strong>Results: </strong>The positive causal relationships were found between dried fruit intake and granulocyte telomere length (OR: 4.31; 95% CI: 1.29 to 14.4; p = 0.02), lymphocyte telomere length (OR: 4.22; 95% CI: 1.21 to 14.7; p = 0.02), naive T-cell telomere length (OR: 5.49; 95% CI: 1.58 to 19.0; p = 0.01). Oily fish intake was positively associated with memory T-cell telomere length (OR: 2.55; 95% CI: 1.16 to 5.58; p = 0.02). No significant causal relationships were found between other exposures and outcomes.</p><p><strong>Conclusions: </strong>This study found positive causal associations between telomere length and the intake of dried fruit and oily fish. No significant causal relationships were observed with other dietary factors. These findings provide insights into how specific dietary components may help maintain telomere length.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"34 5","pages":"783-795"},"PeriodicalIF":1.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490951/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145211557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postprandial glycemic response, sensory, and appetite evaluation of highland barley-multigrain rice versus white rice in healthy Chinese adults: A randomized crossover study.","authors":"Zhaoyin Chu, Hui Ran, Hongmei Zhang, Qing Su","doi":"10.6133/apjcn.202510_34(5).0005","DOIUrl":"10.6133/apjcn.202510_34(5).0005","url":null,"abstract":"<p><strong>Background and objectives: </strong>Consumption of refined white rice, a staple food in most Asian countries, reportedly causes postprandial hyperglycemia and facilitates the development of diabetes. However, cereal grains with low glycemic indices may reduce postprandial glycemic response. We developed a highland barley-multigrain rice by combining traditional Chinese grains including, highland barley, brown rice, oats, corn grit, and buckwheat. This study aimed to evaluate the glycemic impact, sensory attributes, and appetite response of our highland barley-multigrain rice compared to white rice.</p><p><strong>Methods and study design: </strong>In this randomized crossover trial, ten healthy participants consumed highland barley-multigrain rice, white rice, and glucose, each containing 50 g of available carbohydrate under continuous glucose monitoring to compare postprandial glycemic responses over 180 min. The sensory and appetite ratings for the test foods were also evaluated.</p><p><strong>Results: </strong>The glucose response of highland barley-multigrain rice, based on the incremental area under the curve and peak glucose change levels, showed statistically lower values than white rice. The glycemic index at 120 min (42.9±4.4 vs.79.5±8.0, p <0.001) and 180 min (45.3±4.7 vs. 86.1±8.7, p <0.01) after the consumption of highland barley-multigrain rice was all significantly lower than those of regular white rice. Despite its relatively poor taste and overall preference rating, the highland barley-multigrain rice achieved a higher satiety score at 120 min after intake than white rice.</p><p><strong>Conclusions: </strong>As a low-glycemic index food, highland barley-multigrain rice could decrease postprandial glucose response and reduce hunger in healthy adults, indicating a potential role in improving glycemic control for patients with diabetes.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"34 5","pages":"750-758"},"PeriodicalIF":1.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490945/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145211445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dietary inflammatory index and blood inflammatory markers in relation to dyslipidemia: A cross-sectional NHANES study (2009-2018).","authors":"Chenchen Hu, Yuanyuan Huo, Wei Xu, Mingxin Li, Luyao Li, Yulian Sun, Luxi Liu, Jing Cai","doi":"10.6133/apjcn.202510_34(5).0008","DOIUrl":"10.6133/apjcn.202510_34(5).0008","url":null,"abstract":"<p><strong>Background and objectives: </strong>The presence and accumulation of inflammation may exacerbate the develop-ment of dyslipidemia. Therefore, this study aimed to explore the relationship between blood inflammatory markers and the dietary inflammatory index (DII) in American adults as well as their association with dyslipidemia.</p><p><strong>Methods and study design: </strong>This cross-sectional study included participants with complete data on lipid levels, dietary intake, and blood inflammatory markers. The associations between dyslipidemia and two sets of exposures-blood inflammatory markers and the DII-were analysed using weighted univariate and multivariate logistic regression models.</p><p><strong>Results: </strong>Among the 9,441 participants (2009-2018), 6,689 (70.9%) had dyslipidemia. Logistic regression analysis revealed that higher DII quartiles were significantly associated with an increased risk of dyslipidemia, with the fourth quartile exhibiting an odds ratio of 1.33 (95% CI: 1.10-1.62; p < 0.001). Furthermore, DII combined with various blood inflammatory markers was consistently associated with an increased dyslipidemia risk (all OR > 1.0, all p < 0.05). A non-linear relationship was observed between the systemic immune-inflammation index (SII) and dyslipidemia risk, which became significant when the SII exceeded 434.65.</p><p><strong>Conclusions: </strong>DII and blood inflammation markers showed a positive association with dyslipidemia. Nonetheless, these findings still offer valuable insights to public health policymakers for developing evidence-based strategies to prevent dyslipidemia and potentially reduce inflammation-associated dyslipidemia risk.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"34 5","pages":"796-809"},"PeriodicalIF":1.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490946/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145211483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}