Asia Pacific journal of clinical nutrition最新文献

{"title":"Inverse correlation between plasma 3-chlorotyrosine and pinch strength in chronic kidney disease patients.","authors":"Ren Liufu, Shuhuan Hu, Lin Liu, Yun Liu, Chunlei Li, Huimin Hu, Lin Mi, Rongshao Tan","doi":"10.6133/apjcn.202610_35(5).0007","DOIUrl":"10.6133/apjcn.202610_35(5).0007","url":null,"abstract":"<p><strong>Background and objectives: </strong>This cross-sectional study aimed to explore whether plasma myeloperoxidase (MPO) and its active product, 3-chlorotyrosine (3-CT), as markers of inflammation and oxidative stress, have any independent pathophysiological association with sarcopenia-related parameters in patients with chronic kidney disease (CKD).</p><p><strong>Methods and study design: </strong>A total of 292 patients, including 147 on maintenance hemodialysis (HD) and 145 non-dialyzed hospitalized patients with CKD stages 1-5, were enrolled from September 2022 to December 2023 and categorized into three groups: CKD stages 1-2, CKD stages 3-5 (non-dialysis), and CKD stage 5 (HD). Clinical data, anthropometric measurements, and body composition via bioelectrical impedance analysis were collected. Plasma MPO and 3-CT levels were measured by enzyme-linked immunosorbent assay and liquid chromatography-mass spectrometry (LC-MS), respectively.</p><p><strong>Results: </strong>Results showed that as kidney function declined, plasma MPO levels significantly increased across the CKD stage 1-2, stage 3-5, and HD groups [93.5 (72.3, 103.0) ng/mL, 90.8 (76.0, 106) ng/mL, and 102 (80.7, 126) ng/mL, respectively; H = 174, p <0.001]. The prevalence of sarcopenia also increased significantly across CKD stages (17.3%, 17.1%, and 29.9%, respectively; χ² = 6.52, p = 0.038). Interestingly, statistical analysis confirmed a significant inverse association between plasma 3-CT levels and pinch strength (r = -0.148, p = 0.036). However, there were no significant correlation between plasma MPO or 3-CT levels and sarcopenia.</p><p><strong>Conclusions: </strong>The negative association between plasma 3-CT and pinch strength suggests a link between MPO-mediated inflammation/oxidative stress and fine hand muscle dysfunction, which provides a new perspective for evaluating early, subclinical muscle dysfunction in CKD patients.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"35 5","pages":"812-817"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13626805/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149103738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of a walnut-based low carbohydrate diet on fat redistribution and visceral fat accumulation in people with central obesity: A randomized controlled trial.","authors":"Qingqing Dong, Xiaohan Tan, Ping Feng, Qianqian Tian, Qing Jiang, Xiaohua Wang, Lili Wang","doi":"10.6133/apjcn.202610_35(5).0003","DOIUrl":"https://doi.org/10.6133/apjcn.202610_35(5).0003","url":null,"abstract":"<p><strong>Background and objectives: </strong>The aim of this study was to determine whether a walnut-based low carbohydrate diet (w-LCD) promotes fat redistribution and reduces visceral fat accumulation in people with central obesity (CO).</p><p><strong>Methods and study design: </strong>This study was a 12-week prospective randomized controlled trial. CO participants were recruited and assigned to the w-LCD group or high-carbohydrate, low-fat diet (HCD) group. According to \"2021 Guidelines for Medical Nutrition Therapy of Overweight and Obesity\", the HCD program was constructed; based on the HCD program, the w-LCD program was formed by replacing 150 grams/day of staple food with walnuts rich in healthy fat. The visceral fat area (VFA), trunk to leg fat ratio (TLR), and waist-to-hip ratio (WHR) were assessed at baseline and 12 weeks.</p><p><strong>Results: </strong>The Group × Time interaction effects were significant for TLR (η² = 0.071, p = 0.039) and VFA (η² = 0.093, p = 0.014) with moderate effect, and body mass index (BMI, η² = 0.168, p = 0.001) with large effect. Although comparison be-tween groups revealed no significant on TLR, VFA and BMI at 12 weeks, comparison within groups showed all decreased with large effect on TLR (η² = 0.174, p = 0.001), VFA (η² = 0.393, p <0.001) and BMI (η² = 0.399, p <0.001) in the w-LCD group over time.</p><p><strong>Conclusions: </strong>A w-LCD achieves a significantly greater and faster fat reduction over time compared to the control group, providing a solid evidence-based foundation for dietary management in people with CO.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"35 5","pages":"766-778"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13626808/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149103807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementing a programme to treat severe acute malnutrition in Indonesia: What works?","authors":"Moretta D Fauzi, Marinka van der Hoeven, Damayanti D Soekarjo, Rivani Noor, Iin Nurlinawati, Frank T Wieringa, Puspo Edi Giriwono","doi":"10.6133/apjcn.202610_35(5).0001","DOIUrl":"https://doi.org/10.6133/apjcn.202610_35(5).0001","url":null,"abstract":"<p><strong>Background and objectives: </strong>Indonesia, a middle-income country with a large population of young children, is predicted to have a demographic bonus in 2045. However, to benefit from this bonus, the government must optimally manage the triple burden of malnutrition to prevent long-term effects that can significantly decrease quality of life. National data in 2023 showed an increased prevalence of acute malnutrition com-pared to previous years, a wake-up call for the government to address important contributing factors. This article aims to identify the current position of Indonesian guidelines on acute malnutrition (AM) and to provide recommendations.</p><p><strong>Methods and study design: </strong>A document analysis was conducted to examine the existing guidelines for the treatment of acute malnutrition in children under 5 years of age in Indonesia and their implementation.</p><p><strong>Results: </strong>The Ministry of Health published the latest guidelines in 2019 and a technical guide-line for the treatment of moderate acute malnutrition (MAM) in 2024. National guidelines were not uniformly implemented across regions due to several factors, such as funding availability, human resources, and logistics. Of the four main components of the latest severe acute malnutrition (SAM) guideline, hospitalisation management has been adequately implemented. Meanwhile, community mobilisation, the availability of out-patient therapeutic regimens, and treatment for moderate acute malnutrition faced numerous challenges.</p><p><strong>Conclusions: </strong>The implementation of three of the four components of SAM treatment should be improved, with a focus on screening and early detection of acute malnutrition, strengthening the referral system, providing therapeutic regimens, and developing a sustainable reporting system.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"35 5","pages":"750-758"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13626804/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149103752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Construction of risk prediction models for psoriasis based on 45 dietary nutrients using machine learning and SHAP analysis.","authors":"Xin Zhang, Zhe Gao, Jiang-Feng Feng, Xin-Gang Wu","doi":"10.6133/apjcn.202610_35(5).0006","DOIUrl":"https://doi.org/10.6133/apjcn.202610_35(5).0006","url":null,"abstract":"<p><strong>Background and objectives: </strong>To develop and validate a machine learning model to predict the risk of psoriasis based on 45 dietary nutrients.</p><p><strong>Methods and study design: </strong>12,749 participants from the National Health and Nutrition Examination Survey from 2009-2014 were included and their demographic, lifestyle, health status, and dietary nutrient-related information is collected. Imbalanced data were processed using the syn-thetic minority oversampling technique (SMOTE). After removing the covariate features, important features were further screened using the Boruta algorithm and six machine learning models were constructed including Random Forest (RF), Light Gradient Boosting Machine (Light GBM), Kernel K-Nearest Neighbor (K-KNN), L Naive Bayes, Support Vector Machine (SVM) and Extreme Gradient Boosting (XGBoost). The performance of the models was evaluated using benchmarking and the area under the ROC curve (AUC) was the main evaluation metric to choose the optimal machine learning model. Shapley additive explanation (SHAP) values were computed to evaluate each feature's prediction role in the mode.</p><p><strong>Results: </strong>The Boruta algorithm screened 10 baseline features and 23 dietary nutrient features, and six machine learning models were developed based on them. Compared with other machine learning models, XGBoost demonstrated superior prediction ability. SHAP analysis showed that theobromine, lycopene, caffeine, vitamin D, dietary fiber and vitamin E were the key features that influenced the prediction results.</p><p><strong>Conclusions: </strong>The machine learning (ML) algorithm constructed a prediction model for psoriasis by incorporating baseline features and dietary nutrient features. The SHAP values indicate the dominant role of dietary nutrients in the model.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"35 5","pages":"800-811"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13626807/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149103765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Iron status from diet and serum in relation to biological aging acceleration: A NHANES cross-sectional study.","authors":"Qiancheng Cao, Yujie Feng-Gao, Yanan Chen, Wei Li, Chuanshi Hu, Yifei Cao, Xiao Yan, Rong Chen, Xianrong Xu, Fuzhi Lian","doi":"10.6133/apjcn.202610_35(5).0009","DOIUrl":"https://doi.org/10.6133/apjcn.202610_35(5).0009","url":null,"abstract":"<p><strong>Background and objectives: </strong>Iron is essential but potentially toxic; both deficiency and overload may affect aging. Population-level evidence linking iron exposure to biological aging is limited, and aging-based optimal iron ranges are undefined. We examined associations of total, dietary, and supplemental iron intake and serum iron with three biological age (BA) measures and derived optimal ranges.</p><p><strong>Methods and study design: </strong>We analyzed 13,284 U.S. adults (≥20 years) from NHANES 2007-2010 and 2015-2018. BA deviations (PA, GoldBA, LightBA) were derived from clinical biomarkers. Weighted linear and restricted cubic spline (RCS) models assessed associations; optimal ranges were exposure intervals with significantly beneficial associations. Models adjusted for demographics, lifestyle, comorbidities, and diet quality. Subgroup analyses examined sex, age, menopause, and chronic disease.</p><p><strong>Results: </strong>Dietary iron was associated with younger BA (PA β = -0.07; GoldBA β = -0.09 per 2-fold increase), whereas supplemental iron accelerated aging above 18 mg/day (GoldBA β = 0.35 for >18 mg/day). Serum iron showed the strongest benefit (GoldBA β = -0.25 per 2-fold increase), with a U/J-shaped optimal range of 15.2-18.8 µmol/L. Optimal ranges were also identified for total iron (15.7 - 37.3 mg/day) and dietary iron (≥13.6 mg/day). The optimal serum iron range varied by subgroup (wider in postmenopausal women and those with chronic diseases; interaction p <0.05).</p><p><strong>Conclusions: </strong>The iron-aging relationship is source-dependent: dietary iron is protective, supplemental iron >18 mg/day is detrimental, and serum iron 15.2-18.8 µmol/L is optimal. Optimal ranges should be stratified by population.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"35 5","pages":"829-843"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13626799/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149103805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mapping the scientific research on geriatric nutritional assessment (2016-2025): A bibliometric analysis.","authors":"Lihua Ge, Yan Zhang, Ruxue Yan, Junli Zhou, Zhicui Yao","doi":"10.6133/apjcn.202610_35(5).0005","DOIUrl":"https://doi.org/10.6133/apjcn.202610_35(5).0005","url":null,"abstract":"<p><strong>Background and objectives: </strong>Nutritional assessment is a crucial strategy for preventing and managing geriatric syndromes. This study conducted a bibliometric analysis to clarify the research trajectory and evolutionary trends in geriatric nutritional assessment, identify its core research characteristics and cutting-edge directions, and provide an academic reference for research and clinical practice.</p><p><strong>Methods and study design: </strong>A literature search was conducted in the Web of Science Core Collection and Scopus databases on January 7, 2026, limited to English-language original research articles and reviews on geriatric nutritional assessment published between 2016 and 2025. 1725 documents from Web of Science Core Collection and 4458 from Scopus were finally included, and quantitatively analyzed using three bibliometric tools: the R bibliometrix package, VOSviewer, and CiteSpace.</p><p><strong>Results: </strong>The number of global publications in geriatric nutritional assessment showed a sustained upward trend from 2016 to 2024, with preliminary data indicating continued rapid growth in 2025. Three major research hotspots were identified in this field: the development of precision-oriented nutritional risk assessment tools; research on the association between nutritional status and multi-system geriatric syndromes; and targeted nutritional management based on conventional clinical prediction models.</p><p><strong>Conclusions: </strong>The field of global geriatric nutritional assessment has transitioned into a phase of rapid development, diversified integration, and precision orientation. Future research should focus on strengthening international, cross-regional cooperation, integrating interdisciplinary core teams, and accelerating the clinical translation of precision tools to better support elderly nutritional management and global healthy aging.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"35 5","pages":"787-799"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13626800/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149103789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enteral nutrition intolerance: Evidence mapping of definitions and assessment practices to inform future gastric cancer-specific assessment tool development.","authors":"Wei Fu, Qinchen Xu, Rong Zhang, Chunjuan Liu, Xiaodong Wang","doi":"10.6133/apjcn.202610_35(5).0002","DOIUrl":"https://doi.org/10.6133/apjcn.202610_35(5).0002","url":null,"abstract":"<p><strong>Background and objectives: </strong>Enteral nutrition intolerance can limit achievement of nutrition goals, but its definitions and assessment methods vary widely. This review mapped operational definitions and identified evidence gaps relevant to patients after gastrectomy for gastric cancer.</p><p><strong>Methods and study design: </strong>The Web of Science Core Collection was searched for original clinical studies published from 2015 to 2025 that re-ported explicit operational definitions or ascertainment criteria. Study populations, feeding routes, assessment components, incidence rates, and outcomes were charted and synthesized descriptively.</p><p><strong>Results: </strong>Forty-seven studies were included. Most involved critically ill populations, whereas only three focused on patients after gastric cancer surgery. Definitions used heterogeneous combinations of gastrointestinal symptoms, gastric residual volume, feeding interruption or rate reduction, failure to meet energy targets, and other indicators, with inconsistent thresholds and observation windows. A preliminary three-domain framework was identified: gastrointestinal and dumping-related symptoms, route-appropriate objective indicators, and treatment response or feeding adjustments.</p><p><strong>Conclusions: </strong>Existing definitions are heterogeneous and largely derived from intensive care settings. Standardized reporting and disease-specific validation are required before a gastric cancer-specific assessment tool can be developed.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"35 5","pages":"759-765"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13626802/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149103727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations of percentage body cell mass with insulin resistance and type 2 diabetes: mediation effect of body mass index.","authors":"Yan Wang, Qiang Lu, Lei Zhang, Guimei Wei, Xueyan Shen, Yan Peng","doi":"10.6133/apjcn.202610_35(5).0008","DOIUrl":"https://doi.org/10.6133/apjcn.202610_35(5).0008","url":null,"abstract":"<p><strong>Background and objectives: </strong>Type 2 diabetes (T2D) stems from metabolic dysregulation, and body cell mass (BCM) comprises the principal physiological substrate of basal metabolic rate (BMR); however, the as-sociation between BCM and diabetes is still unclear. This study examined the relationship of percentage body cell mass (PBCM) with insulin resistance (IR) and T2D, and evaluated the mediators of this association.</p><p><strong>Methods and study design: </strong>This study utilized data from U.S. adults in the National Health and Nutrition Survey (1999-2004). Weighted multivariate regression, restricted cubic spline analysis, subgroup analyses, and sensitivity analysis were employed to investigate the relationship of PBCM with T2D risk biomarkers, IR and T2D. The potential mediating role of body mass index (BMI) was explored.</p><p><strong>Results: </strong>A total of 2,923 participants aged 18 years or older were included. Preliminary analysis demonstrated an inverse association between PBCM and biomarkers of T2D risk. Further analyses revealed that higher PBCM was associated with lower odds of IR (OR = 0.91, 95% CI: 0.88-0.94, p <0.001) and T2D (OR = 0.89, 95% CI: 0.84-0.94, p <0.001) in the fully adjusted model. Mediation analysis indicated that BMI mediated 70.6% (95% CI: 55.1%-88.9%, p <0.001) of the total effect of PBCM on IR, and 29.9% (95% CI: 14.2%-65.9%, p <0.001) of that on T2D, respectively.</p><p><strong>Conclusions: </strong>PBCM was negatively associated with the prevalence of IR and T2D. Mediation analyses demonstrated a mediating effect of BMI, suggesting that PBCM might be related to IR and T2D, potentially mediated by BMI.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"35 5","pages":"818-828"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13626803/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149103732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Discrepancy between self-perceived dietary habits and objective clinical risk of liver fibrosis: A cross-sectional study of Japanese health checkup participants.","authors":"Nao Kawabata, Naoki Morimoto, Mizuho Shimada, Shizukiyo Ishikawa, Kentaro Kurashina","doi":"10.6133/apjcn.202610_35(5).0004","DOIUrl":"https://doi.org/10.6133/apjcn.202610_35(5).0004","url":null,"abstract":"<p><strong>Background and objectives: </strong>Lifestyle modification is the cornerstone of liver disease management; however, its success depends on accurate self-assessment. We investigated the clinical characteristics of individuals at risk of liver fibrosis and the discrepancy between their objective risk and self-perceived lifestyle habits in patients with steatotic liver disease.</p><p><strong>Methods and study design: </strong>This cross-sectional study included 167 par-ticipants diagnosed with steatotic liver disease. Participants were categorized into a high-risk group (n = 57) and a control group (n = 110) based on the age-adjusted Fibrosis-4 index cutoffs. Multivariable logistic regression was used to identify independent factors, and self-perceived habits were compared to evaluate cognitive-clinical discrepancies.</p><p><strong>Results: </strong>Age was identified as the sole independent clinical factor associated with the risk of fibrosis. The high-risk group exhibited significantly lower alanine aminotransferase and tri-glyceride levels than those of the control group. Despite their higher clinical risk, the high-risk group reported significantly higher engagement in habitual exercise (53% vs. 31%, p = 0.006) and restorative sleep (odds ratio: 3.24). High-risk individuals were also significantly less likely to report the frequent intake of sweets (odds ratio: 0.253).</p><p><strong>Conclusions: </strong>A profound cognitive-clinical discrepancy exists among individuals at risk for liver fibrosis, which may lead them to misinterpret pathologically declining biomarkers as successful out-comes of their lifestyle efforts. Health promotion must move beyond general advice to incorporate perception-correcting feedback that reconciles subjective health views with objective pathological realities.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"35 5","pages":"779-786"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13626801/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149103748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fiber-rich snacks improved constipation in Vietnamese elderly.","authors":"Yen Hoang Thi Hai, Linh Thuy Nguyen, An Thanh Truong, Ryosuke Matsuoka, Phu Nguyen Dinh, Linh Hoang Khanh, Van Anh Nguyen Thi, Cuong Doan Huy, Shigeru Yamamoto","doi":"10.6133/apjcn.202608_35(4).0009","DOIUrl":"10.6133/apjcn.202608_35(4).0009","url":null,"abstract":"<p><strong>Background and objectives: </strong>Constipation is a common condition among the elderly in nursing homes, partly due to a low fiber intake. This study utilized agar and konjac, both rich sources of dietary fiber, to develop fiber-rich snacks aimed at increasing fiber intake among the elderly.</p><p><strong>Methods and study design: </strong>This 3-week cross-over study was conducted among 20 elderly residents with constipation at Tuyet Thai Nursing Home, Vietnam (11 women, mean age 77 years; 9 men, mean age 79 years). Participants were divided into two groups receiving either control or fiber-rich snacks in alternating weeks, with a washout week in between. Two snacks were provided each day - control snacks made with tapioca and gelatin and intervention snacks in which part of the tapioca was replaced with konjac (≈3g fiber) and all gelatin with agar (≈3g fiber). Data were collected on stool status, dietary intake, and quality of life (as assessed by the Patient Assessment of Constipation Quality of Life (PAC-QOL) questionnaire).</p><p><strong>Results: </strong>Comparison of defecation status with the control period and the intervention period: stool frequency: 3.3 times/week and 4.9 times/week; The propor-tion of bowel movements with normal stool form increased from 35% to 85%; with stool constipation form decreased from 56% to 14% (p <0.05). Energy intake was comparable between periods, whereas fiber intake increased substantially during the intervention (11.8 ± 1.6 vs. 6.1 ± 1.2 g/day). The difference in fiber intake between the two periods was statistically significant (p <0.05), while the difference in energy intake was not statistically significant (p >0.05). The quality of life scores of the elderly during the intervention period im-proved significantly.</p><p><strong>Conclusions: </strong>Fiber-rich snacks effectively improved constipation in the elderly without affecting their energy intake.</p>","PeriodicalId":8486,"journal":{"name":"Asia Pacific journal of clinical nutrition","volume":"35 4","pages":"656-665"},"PeriodicalIF":1.6,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13413141/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148598203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}