Artery ResearchPub Date : 2020-12-01DOI: 10.2991/artres.k.201209.053
K. Raj, P. Nabeel, J. Joseph, Dinu S. Chandran, M. Sivaprakasam
{"title":"P.41 Measurement of Pressure-dependent Intra-Beat Changes in Carotid Pulse Wave Velocity using Image-Free Fast Ultrasound","authors":"K. Raj, P. Nabeel, J. Joseph, Dinu S. Chandran, M. Sivaprakasam","doi":"10.2991/artres.k.201209.053","DOIUrl":"https://doi.org/10.2991/artres.k.201209.053","url":null,"abstract":"Background: The clinical significance of pressure-dependent intra-beat changes in local pulse-wave velocity (C) has recently come to light [1]. While reported methods require arterial pressure and diameter measurements from a single site to assess intrabeat changes in C, we present an image-free fast ultrasound device that performs this by capturing diameter waveforms from two proximal locations on an artery.. Methods: The functionality was assessed on eight normotensive participants (26 ± 4 years). By perturbing blood pressure through a short duration moderate lower body negative pressure intervention [2], CD and CF pulse wave velocities corresponding to diastolic and 80% of peak pressure were measured from the carotid artery. Human NIBP system (ADInstruments, India) was used for monitoring continuous pressure.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42777069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Artery ResearchPub Date : 2020-12-01DOI: 10.2991/artres.k.201209.040
A. A. Borzykh, I. Kuzmin, O. Vinogradova, O. Tarasova
{"title":"P.27 Mechanisms of NADPH Oxidase Participation in the Regulation of Diaphragm Artery Contractile Responses","authors":"A. A. Borzykh, I. Kuzmin, O. Vinogradova, O. Tarasova","doi":"10.2991/artres.k.201209.040","DOIUrl":"https://doi.org/10.2991/artres.k.201209.040","url":null,"abstract":"Reactive oxygen species (ROS) produced by NADPH-oxidase (NOX) participate in vascular tone control, but their effects in the arteries of respiratory muscles is poorly understood. Possible targets of vasoregulatory ROS influence are NO-pathway in the endothelium and Rho-kinase pathway in smooth muscle cells. Therefore, the aim of this study was to evaluate the interaction of NOX-dependent control with NOand Rho-kinase signaling pathways in rat diaphragm arteries (DA).","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47986936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Artery ResearchPub Date : 2020-12-01DOI: 10.2991/artres.k.201209.003
April C E van Gennip, Sanaz Sedeghat, M. Carnethon, N. Allen, B. Klein, M. Cotch, D. Chirinos, C. Stehouwer, T. Sloten
{"title":"YI 1.3 Retinal Microvascular Calibers and Incident Depressive Symptoms: The Multi-Ethnic Study of Atherosclerosis","authors":"April C E van Gennip, Sanaz Sedeghat, M. Carnethon, N. Allen, B. Klein, M. Cotch, D. Chirinos, C. Stehouwer, T. Sloten","doi":"10.2991/artres.k.201209.003","DOIUrl":"https://doi.org/10.2991/artres.k.201209.003","url":null,"abstract":"Background: Cerebral microvascular dysfunction may contribute to depression via disruption of brain structures involved in mood regulation, but evidence is scarce. The retina allows for direct visualisation of a microvascular bed that shares anatomical and physiological similarities with the cerebral microvasculature. We investigated the association between baseline central retinal arteriolar and venular calibers (CRAE and CRVE) and 7.8-year change of CRAE and CRVE and incident depressive symptoms.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48158659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Artery ResearchPub Date : 2020-12-01DOI: 10.2991/artres.k.201209.069
M. Baumgartner, H. Weberruss, Katharina Appel, T. Engl, R. Oberhoffer-Fritz, T. Schulz
{"title":"P.60 Improvement in Muscular Strength Within One Year is Associated with Increased Arterial Stiffness in Young Male Soccer Players","authors":"M. Baumgartner, H. Weberruss, Katharina Appel, T. Engl, R. Oberhoffer-Fritz, T. Schulz","doi":"10.2991/artres.k.201209.069","DOIUrl":"https://doi.org/10.2991/artres.k.201209.069","url":null,"abstract":"Methods: 30 male soccer players were examined twice (age t0: 13.3 ± 2.0 years, age t1: 14.2 ± 2.0 years). cSBP and aPWV were measured oscillometrically (Mobil-O-Graph®) and z-scores were calculated. The MoMo physical activity questionnaire recorded the weekly training load and the hand dynamometer measured muscular strength. Height and weight were examined and body surface area (BSA) was computed.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41925697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Artery ResearchPub Date : 2020-12-01DOI: 10.2991/artres.k.201209.064
M. Bukhamseen, Nada Al-Saileek, A. Alsaileek, Mohammad Ghormalla Ghamdi, Tahlil Wasame, A. Omran, Azra Mahmud
{"title":"P.54 Biomarkers and Haemodynamic Predictors of Left Atrial Strain in Early Hypertension","authors":"M. Bukhamseen, Nada Al-Saileek, A. Alsaileek, Mohammad Ghormalla Ghamdi, Tahlil Wasame, A. Omran, Azra Mahmud","doi":"10.2991/artres.k.201209.064","DOIUrl":"https://doi.org/10.2991/artres.k.201209.064","url":null,"abstract":"Methods: We studied 34 patients, mean age 47.5 ± 11.6 years, 56% females. All parameters for arterial stiffness including 24 hour central systolic pressure, augmentation index and pulse wave velocity were measured non–invasively using Mobil-Ograph PWA. All patients underwent standard two-dimensional echocardiography with Spackle tracking analysis for left atrium (LA). Circulating biomarkers including renin, aldosterone and morning cortisol were measured using ELISA.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46734548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Artery ResearchPub Date : 2020-12-01DOI: 10.2991/artres.k.201209.061
A. Guala, M. Pons, A. Ruiz-Muñoz, L. Dux-Santoy, L. Madrenas, M. Gandara, F. Valente, Á. López-Sainz, L. Galián, L. Gutiérrez, A. Sao-Avilés, T. González‐Alujas, I. Ferreira, A. Evangelista, J. Rodríguez-Palomares, G. Teixidó-Tura
{"title":"P.49 Aortic Root Longitudinal Strain by Speckle-Tracking Echocardiography: Comparison with Cardiac Magnetic Resonance and Predictive Value in Marfan Syndrome Patients","authors":"A. Guala, M. Pons, A. Ruiz-Muñoz, L. Dux-Santoy, L. Madrenas, M. Gandara, F. Valente, Á. López-Sainz, L. Galián, L. Gutiérrez, A. Sao-Avilés, T. González‐Alujas, I. Ferreira, A. Evangelista, J. Rodríguez-Palomares, G. Teixidó-Tura","doi":"10.2991/artres.k.201209.061","DOIUrl":"https://doi.org/10.2991/artres.k.201209.061","url":null,"abstract":"Background: Low longitudinal strain of the ascending aorta (AAo) by cardiac magnetic resonance (CMR) predicts dilation and aortic events in Marfan syndrome (MFS) [1], possibly reflecting aortic stiffness [2]. Speckle-tracking is established for cardiac deformation, but proximal aorta applications are challenging due to wall thickness and substantial motion. We aimed to validate a purpose-specific speckle-tracking tool for root longitudinal strain analysis by comparison with CMR-derived AAo longitudinal strain and as predictor of dilation in MFS patients.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":"26 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69871966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Artery ResearchPub Date : 2020-11-01DOI: 10.2991/artres.k.201031.001
M. Holmstrup, J. D. Keyser, B. Jensen
{"title":"Methodological Consideration for Endothelial Function Assessment based on Bilateral Differences","authors":"M. Holmstrup, J. D. Keyser, B. Jensen","doi":"10.2991/artres.k.201031.001","DOIUrl":"https://doi.org/10.2991/artres.k.201031.001","url":null,"abstract":"Examining the characteristics and responses of an individual’s vascular system is important for improving the early detection, prevention, and treatment of cardiovascular disease. For example, applanation tonometry is a common means of assessing arterial stiffness, with precise standards established for measurement [1]. Previous studies have examined potential differences in arterial stiffness between arms [2–5], with conflicting findings. Further, while the assessment of arterial stiffness can provide a snapshot of vascular health at rest, information on dynamic vascular function can be determined by assessing the change in Pulse Wave Velocity (PWV) in response to a condition of reactive hyperemia [6–16].","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43864035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Artery ResearchPub Date : 2020-11-01DOI: 10.2991/artres.k.201102.002
Thapanee Roengrit, Ruchada Sri-Amad, N. Huipao
{"title":"High Systolic Blood Pressure is Associated with Increased Cardio-ankle Vascular Index in the Elderly","authors":"Thapanee Roengrit, Ruchada Sri-Amad, N. Huipao","doi":"10.2991/artres.k.201102.002","DOIUrl":"https://doi.org/10.2991/artres.k.201102.002","url":null,"abstract":"Background: Increased arterial stiffness caused by elevated Blood Pressure (BP) can be indicated by the Cardio-ankle Vascular Index (CAVI). However, the relationship between arterial stiffness and BP is complex. In addition, changes in BP may contribute to increased risk of cardiovascular disease associated with abnormal lipid profiles. So far, results from published studies have been inconclusive. Objectives: To evaluate lipid profiles and BP, and their association with CAVI values in elderly participants. Methods: The study included 95 elderly Thai individuals. Anthropometric data, lipid profiles, and BP and CAVI values were established. Participants were then divided into low-CAVI (CAVI < 9, n = 50) and high-CAVI groups (CAVI ≥ 9, n = 45). Stepwise linear and logistic regression models were used. Results: The high-CAVI group had significantly higher BP and hypertension levels, than the low-CAVI group. The mean age of the high-CAVI group was also higher (≥65 years). CAVI value was positively correlated with Systolic Blood Pressure (SBP) and Pulse Pressure (PP) in the high-CAVI group. Stepwise multiple regression analysis showed SBP ( b = 0.43, p < 0.01) and hip circumference ( b = −0.23, p = 0.01) were associated with CAVI values. Logistic regression of the high-CAVI indices showed that the Odds Ratios (ORs) for the factors of age ≥65 years, obesity, hypertension","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44815205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Artery ResearchPub Date : 2020-11-01DOI: 10.2991/artres.k.201102.004
D. Marcon, L. Faconti, B. Farukh, R. Mcnally, C. Fava, M. Pengo, P. Chowienczyk, J. Cruickshank
{"title":"Does Treatment for Obstructive Sleep Apnoea Improve Arterial Stiffness? Evidence from Randomized Clinical Trials on Carotid-femoral Pulse Wave Velocity","authors":"D. Marcon, L. Faconti, B. Farukh, R. Mcnally, C. Fava, M. Pengo, P. Chowienczyk, J. Cruickshank","doi":"10.2991/artres.k.201102.004","DOIUrl":"https://doi.org/10.2991/artres.k.201102.004","url":null,"abstract":"","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49339214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Artery ResearchPub Date : 2020-11-01DOI: 10.2991/artres.k.201102.005
M. Cook, Chenyi Ling, Heather Grimm, Adelola O Adeyemo, Maitha Aldokhayyil, K. Heffernan, B. Fernhall, Michael D. Brown
{"title":"Primary African American Endothelial Cells Exhibit Endothelial Dysfunction with an Exacerbated Inflammatory Profile and Blunted MMP-2 Activity","authors":"M. Cook, Chenyi Ling, Heather Grimm, Adelola O Adeyemo, Maitha Aldokhayyil, K. Heffernan, B. Fernhall, Michael D. Brown","doi":"10.2991/artres.k.201102.005","DOIUrl":"https://doi.org/10.2991/artres.k.201102.005","url":null,"abstract":"1Department of Kinesiology, North Carolina Agricultural and Technical State University, Greensboro, NC, USA 2Department of Biology, University of Alaska, Fairbanks, AK, USA 3Department of Exercise Science, Kings College, Wilkes-Barre, PA, USA 4School of Kinesiology, Auburn University, Auburn, AL, USA 5School of Medicine-Geriatrics, University of Utah, Salt Lake City, UT, USA 6Department of Exercise Science, Syracuse University, Syracuse, NY, USA 7Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL, USA","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43947806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}