P.65无心血管合并症的自身免疫性类风湿性疾病患者内皮功能障碍和血栓微环境的生物标志物增加

IF 0.9 4区医学 Q4 PERIPHERAL VASCULAR DISEASE

Artery Research Pub Date : 2020-12-01 DOI:10.2991/artres.k.201209.074

E. Gavriilaki, P. Anyfanti, S. Douma, E. Gkaliagkousi

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引用次数: 0

摘要

目的/背景/目的：自身免疫性风湿性疾病患者的心血管风险增加[1]。内皮和血小板MVs（EMVs，PMVs）是从质膜释放的小泡（0.1–1μm），是内皮功能障碍和血栓形成的新标志物。它们的水平在心血管疾病患者中显著增加[2，3]。我们测试了在没有心血管合并症的情况下，自身免疫性风湿性疾病患者的EMV和PMV是否增加。

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P.65 Increased Biomarkers of Endothelial Dysfunction and Thrombotic Microenvironment in Patients with Autoimmune Rheumatic Disorders Free from Cardiovascular Comorbidities

Purpose/Background/Objectives: Cardiovascular risk is increased in patients with autoimmune rheumatic disorders [1]. Endothelial and platelet MVs (EMVs, PMVs) are small vesicles (0.1–1 μm) released from plasma membrane and represent novel markers of endothelial dysfunction and thrombosis. Their levels increase substantially in patients with cardiovascular diseases [2,3]. We tested whether EMVs and PMVs are increased in patients with autoimmune rheumatic disorders in the absence of cardiovascular comorbidities.

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来源期刊

Artery Research Medicine-Cardiology and Cardiovascular Medicine

CiteScore

1.70

自引率

16.70%

发文量

审稿时长

13 weeks

期刊介绍： Artery Research is the official journal of the Association for Research into Arterial Structure and Physiology (ARTERY) which promotes the advancement of knowledge and dissemination of information concerning the pathophysiology, epidemiology, detection, investigation and treatment of arterial structure and function. The journal publishes original research articles, review articles, perspectives, case-studies, letters to the Editor, short communications and images. All submitted material is subject to a strict peer-review process.