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P.40 Ambulatory Measurement of Carotid Stiffness with a Novel Accelerometric System P.40用新型加速度计系统动态测量颈动脉硬度
IF 0.6 4区 医学
Artery Research Pub Date : 2020-12-01 DOI: 10.2991/artres.k.201209.052
R. Arathy, P. Nabeel, J. Jayaraj, V. Abhidev, S. Mohanasankar
{"title":"P.40 Ambulatory Measurement of Carotid Stiffness with a Novel Accelerometric System","authors":"R. Arathy, P. Nabeel, J. Jayaraj, V. Abhidev, S. Mohanasankar","doi":"10.2991/artres.k.201209.052","DOIUrl":"https://doi.org/10.2991/artres.k.201209.052","url":null,"abstract":"Purpose: Arterial stiffness is a well-established marker for cardiovascular health assessment. Current methods rely on expensive imaging systems and specialised operators to perform local stiffness evaluation from the common carotid artery (CCA) and cannot be used for ambulatory monitoring in chronic disease management. In this study, we compare the performance of a novel accelerometric system, which performs ambulatory non-invasive CCA stiffness measurement, against an ultrasoundbased stiffness monitor.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41755412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P.24 Factors Associated with Premature Vascular Aging in Patients with Arterial Hypertension P.24高血压患者血管过早衰老的相关因素
IF 0.6 4区 医学
Artery Research Pub Date : 2020-12-01 DOI: 10.2991/artres.k.201209.037
I. V. Melekhina, E. G. Medvedeva, S. V. Ivanova, E. Yushchuk, E. Trush
{"title":"P.24 Factors Associated with Premature Vascular Aging in Patients with Arterial Hypertension","authors":"I. V. Melekhina, E. G. Medvedeva, S. V. Ivanova, E. Yushchuk, E. Trush","doi":"10.2991/artres.k.201209.037","DOIUrl":"https://doi.org/10.2991/artres.k.201209.037","url":null,"abstract":"Methods: The study included 61 patients (29 men, 32 women) with 1–2 grade AH without cardiovascular complications, aged 40 to 60 years, of which 28 (45.9%) had type 2 diabetes. The duration of AH was 5.0 [2.0; 10.0] years, type 2 diabetes 2.0 [1.0; 4.0] years. The assessment of vascular stiffness using cardio-ankle vascular index (CAVI) and vascular age (VA) was performed by volumetric sphygmography (VaSera-1500). All patients were divided into 2 groups: with normal VA (the passport age corresponds to the VA, n = 35) and premature vascular aging (the VA is higher than the passport age, n = 26).","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46398861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P.42 The Effects of Chemotherapy on Arterial Stiffness in Patients with Hodgkin Lymphoma P.42化疗对霍奇金淋巴瘤患者动脉硬化的影响
IF 0.6 4区 医学
Artery Research Pub Date : 2020-12-01 DOI: 10.2991/artres.k.201209.054
C. Anagnostopoulos, S. Giannouli, N. Ioakimidis, P. Kafouris, I. Koutagiar, A. Sioni, E. Solomou, D. Terentes-Printzios, D. Tousoulis, C. Vlachopoulos
{"title":"P.42 The Effects of Chemotherapy on Arterial Stiffness in Patients with Hodgkin Lymphoma","authors":"C. Anagnostopoulos, S. Giannouli, N. Ioakimidis, P. Kafouris, I. Koutagiar, A. Sioni, E. Solomou, D. Terentes-Printzios, D. Tousoulis, C. Vlachopoulos","doi":"10.2991/artres.k.201209.054","DOIUrl":"https://doi.org/10.2991/artres.k.201209.054","url":null,"abstract":"1Hippokration General Hospital, 1st Cardiology Department, Athens Medical School 2Academy of Athens Biomedical Research Foundation, Center for Experimental Surgery, Clinical and Translational Research, Biomedical Research Foundation 3Academy of Athens Biomedical Research Foundation, Center of Systems Biology 4Hippokration General Hospital, Department of Hematology 5Academy of Athens Biomedical Research Foundation, Center of Systems Biology","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43665584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P.32 Non-Invasive Measures of Arteriosclerosis Across Childhood and Adolescence: Insights Into the Natural History of Disease P.32儿童和青少年动脉硬化的无创测量:对疾病自然史的洞察
IF 0.6 4区 医学
Artery Research Pub Date : 2020-12-01 DOI: 10.2991/artres.k.201209.045
Reeja F. Nasir, T. Y. Cai, Alice Meroni, M. Skilton
{"title":"P.32 Non-Invasive Measures of Arteriosclerosis Across Childhood and Adolescence: Insights Into the Natural History of Disease","authors":"Reeja F. Nasir, T. Y. Cai, Alice Meroni, M. Skilton","doi":"10.2991/artres.k.201209.045","DOIUrl":"https://doi.org/10.2991/artres.k.201209.045","url":null,"abstract":"Objectives: Non-invasive methodologies for assessing arteriosclerosis, including carotid intimal-medial thickness (cIMT) for assessing subclinical atherosclerosis and carotid-femoral pulse wave velocity (cfPWV) for measuring arterial stiffness, are well established and validated in adults [1, 2]. However, they are less well-described in children. Alternative methodologies, such as aortic IMT (aIMT), may be more appropriate in children provided the natural history of atherosclerotic disease [3]. Previous studies have predominantly applied these methodologies in a narrow age-range of children; methodological differences between studies make inter-study comparison of absolute values difficult. Therefore, we aimed to assess the severity of arteriosclerosis across childhood and adolescence using standardised application of age-appropriate and established methodologies.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45166633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P.22 Mortality in 98 Type 1 Diabetes Mellitus (T1DM) and Type 2 Diabetes Mellitus (T2DM) Individuals Presenting to a Specialist Podiatry Clinic: Foot Ulcer Location is an Independent Risk Determinant P.22 98例就诊于专科足病诊所的1型糖尿病(T1DM)和2型糖尿病(T2DM)患者的死亡率:足部溃疡位置是一个独立的风险决定因素
IF 0.6 4区 医学
Artery Research Pub Date : 2020-12-01 DOI: 10.2991/artres.k.201209.035
Heather Schofield, S. Haycocks, A. Robinson, S. Anderson, A. Heald
{"title":"P.22 Mortality in 98 Type 1 Diabetes Mellitus (T1DM) and Type 2 Diabetes Mellitus (T2DM) Individuals Presenting to a Specialist Podiatry Clinic: Foot Ulcer Location is an Independent Risk Determinant","authors":"Heather Schofield, S. Haycocks, A. Robinson, S. Anderson, A. Heald","doi":"10.2991/artres.k.201209.035","DOIUrl":"https://doi.org/10.2991/artres.k.201209.035","url":null,"abstract":"Results: Seventeen people (17) had type 1 diabetes mellitus (T1DM), and 81 had type 2 diabetes mellitus (T2DM). 31 were women. The mean age (range) was 63.6 (28–90) years with maximum diabetes duration 45 years. Mean HbA1c was 72 (95% CI: 67–77) mmol/mol. 97% had neuropathy (International Working Group on the Diabetic Foot (IWGDF) monofilament) [2]. 62% had vascular insufficiency (Doppler studies). 69% of ulcers were forefoot and 23% of ulcers were hind foot in location. 40/98 (39.2%) died in follow-up with 27% of death certificates including sepsis (not foot-related) and 35% renal failure as cause of death. Multivariate regression analysis indicated a 6.3 (95% CI: 3.9–8.1) fold increased risk of death with hind foot ulcer, independent of age/BMI/gender/HbA1c/eGFR/total cholesterol level.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48039557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P.65 Increased Biomarkers of Endothelial Dysfunction and Thrombotic Microenvironment in Patients with Autoimmune Rheumatic Disorders Free from Cardiovascular Comorbidities P.65无心血管合并症的自身免疫性类风湿性疾病患者内皮功能障碍和血栓微环境的生物标志物增加
IF 0.6 4区 医学
Artery Research Pub Date : 2020-12-01 DOI: 10.2991/artres.k.201209.074
E. Gavriilaki, P. Anyfanti, S. Douma, E. Gkaliagkousi
{"title":"P.65 Increased Biomarkers of Endothelial Dysfunction and Thrombotic Microenvironment in Patients with Autoimmune Rheumatic Disorders Free from Cardiovascular Comorbidities","authors":"E. Gavriilaki, P. Anyfanti, S. Douma, E. Gkaliagkousi","doi":"10.2991/artres.k.201209.074","DOIUrl":"https://doi.org/10.2991/artres.k.201209.074","url":null,"abstract":"Purpose/Background/Objectives: Cardiovascular risk is increased in patients with autoimmune rheumatic disorders [1]. Endothelial and platelet MVs (EMVs, PMVs) are small vesicles (0.1–1 μm) released from plasma membrane and represent novel markers of endothelial dysfunction and thrombosis. Their levels increase substantially in patients with cardiovascular diseases [2,3]. We tested whether EMVs and PMVs are increased in patients with autoimmune rheumatic disorders in the absence of cardiovascular comorbidities.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49129811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P.14 Transcranial Colour Duplex Reveals Haemodynamically Significant Venous Flow Alterations Following Resection of Arteriovenous Malformation of the Brain 经颅彩色双工显示脑动静脉畸形切除术后显著的血流动力学改变
IF 0.6 4区 医学
Artery Research Pub Date : 2020-12-01 DOI: 10.2991/artres.k.201209.027
K. Busch, A. Davidson, M. Butlin, A. Avolio, H. Kiat
{"title":"P.14 Transcranial Colour Duplex Reveals Haemodynamically Significant Venous Flow Alterations Following Resection of Arteriovenous Malformation of the Brain","authors":"K. Busch, A. Davidson, M. Butlin, A. Avolio, H. Kiat","doi":"10.2991/artres.k.201209.027","DOIUrl":"https://doi.org/10.2991/artres.k.201209.027","url":null,"abstract":"Background: Resection of a brain arteriovenous malformation (bAVM) can impose several post-operative challenges including postoperative haemorrhage (POH) [1]. The mechanism of such complications remains controversial although deliberately inducing hypotension has proven successful for POH prevention [2]. Daily non-invasive monitoring for patients may be useful in predicting POH. Transcranial color duplex (TCCD) and central aortic pressures (CAP) can be derived non-invasively providing pressure and haemodynamic measurements. These techniques may provide valuable insight into the process of vessel remodeling following bAVM resection.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47050224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P.58 Genetic Background Dictates Aortic Fibrosis in Hypertensive Mice P.58遗传背景决定了高血压小鼠的主动脉纤维化
IF 0.6 4区 医学
Artery Research Pub Date : 2020-12-01 DOI: 10.2991/artres.k.201209.068
B. Spronck, M. Latorre, S. Mehta, A. Caulk, A. Ramachandra, Sae-Il Murtada, Alexia Rojas, Changyuan He, Bo Jiang, Mo Wang, M. Bersi, G. Tellides, J. Humphrey
{"title":"P.58 Genetic Background Dictates Aortic Fibrosis in Hypertensive Mice","authors":"B. Spronck, M. Latorre, S. Mehta, A. Caulk, A. Ramachandra, Sae-Il Murtada, Alexia Rojas, Changyuan He, Bo Jiang, Mo Wang, M. Bersi, G. Tellides, J. Humphrey","doi":"10.2991/artres.k.201209.068","DOIUrl":"https://doi.org/10.2991/artres.k.201209.068","url":null,"abstract":"Methods: After AngII infusion (14-day, 1000 ng/kg/min) and euthanasia, excised thoracic aortas were characterized functionally using isobaric vasoactive and cyclic passive stiffness tests. Immunohistochemistry quantified medial/adventitial composition and infiltration of pan-inflammatory CD45+ cells. RNA sequencing-based gene ontology, wall stress analyses, and growth and remodeling (G&R) simulations were performed to complement our mechanical findings.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49663116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
YI 1.2 Ideal Cardiovascular Health Score Declines from Adolescence to Emerging Adulthood YI 1.2理想心血管健康评分从青春期到成年期下降
IF 0.6 4区 医学
Artery Research Pub Date : 2020-12-01 DOI: 10.2991/artres.k.201209.002
Chloe M. Park, Siana Jones, Suzanne Williams, A. Rapala, H. Taylor, L. Howe, A. Fraser, N. Chaturvedi, A. Hughes
{"title":"YI 1.2 Ideal Cardiovascular Health Score Declines from Adolescence to Emerging Adulthood","authors":"Chloe M. Park, Siana Jones, Suzanne Williams, A. Rapala, H. Taylor, L. Howe, A. Fraser, N. Chaturvedi, A. Hughes","doi":"10.2991/artres.k.201209.002","DOIUrl":"https://doi.org/10.2991/artres.k.201209.002","url":null,"abstract":"Methods: 3142 participants from the Avon Longitudinal Study of Parents and Children (ALSPAC) study attended clinical investigations at 17.8 ± 0.4 yrs and 24.0 ± 0.8 yrs (38% male). CV health was assessed using smoking status, body mass index (BMI), plasma glucose, cholesterol, sitting brachial blood pressure, left ventricle (LV) hypertrophy, arterial stiffness (carotid-tofemoral pulse wave velocity) and atherosclerosis (carotid intima-media thickness) metrics. Prevalence was stratified into poor (0_points), intermediate (1_point) and ideal (2_points) health categories and a composite, individual-level CHS for all 8 metrics was calculated (total range, 0–16 points). Prevalence of ideal health was assessed using ANOVA and linear mixed modelling assessed age##sex modifications.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45903175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P.66 Radial Artery Systolic-Diastolic Pulse Transit Time After Kidney Transplantation P.66肾移植后桡动脉收缩期-舒张期脉搏传递时间
IF 0.6 4区 医学
Artery Research Pub Date : 2020-12-01 DOI: 10.2991/artres.k.201209.075
E. Philibert, H. Obeid, M. Paré, N. Côté, C. Fortier, R. Goupil, M. Agharazii
{"title":"P.66 Radial Artery Systolic-Diastolic Pulse Transit Time After Kidney Transplantation","authors":"E. Philibert, H. Obeid, M. Paré, N. Côté, C. Fortier, R. Goupil, M. Agharazii","doi":"10.2991/artres.k.201209.075","DOIUrl":"https://doi.org/10.2991/artres.k.201209.075","url":null,"abstract":"Methods: Before and three months after KTx, we obtained radial pressure waveforms using applanation tonometry, in a group of 61 patients with restored renal function (eGFR > 45 ml/min/1,73 m2). Radial waveforms were recorded over a 10 seconds period and ensemble-averaged (using in house-MATLAB program) to obtain a single waveform and then modelled using two Gaussian functions, was then determined as the transit time between the first systolic peak T1 and the early diastolic peak T2.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47641190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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