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P.20 Evolving Structure-Function Correlates during Aortic Maturation and Aging P.20主动脉成熟与衰老过程中结构与功能的演化关系
IF 0.6 4区 医学
Artery Research Pub Date : 2020-12-01 DOI: 10.2991/artres.k.201209.033
C. Cavinato, J. Humphrey
{"title":"P.20 Evolving Structure-Function Correlates during Aortic Maturation and Aging","authors":"C. Cavinato, J. Humphrey","doi":"10.2991/artres.k.201209.033","DOIUrl":"https://doi.org/10.2991/artres.k.201209.033","url":null,"abstract":"Methods: This study, combining ex-vivo extension-inflation testing [2], multiphoton microscopy and optical histology, aimed to quantify multiple microstructural parameters of primary extracellular components – collagen, elastic lamellae – and cells – endothelial, smooth muscle and adventitia cells – of the aorta with a dynamic and multiregional 3D approach. The analysis focused on the quantification and correlation of the histo-mechanical properties of the thoracic aorta as a function of age from 21 days to 1 year after birth, that is, from the time of weaning to maturation and therefore the natural aging. The parameters quantifying the three-dimensional microstructural phenomena of deposition, remodeling and removal of aortic components under pressure and stretch conditions equivalent to those in vivo were layer thicknesses, straightening, alignment and thickness of collagen bundles, number and size of elastic lamellae, density and alignment of the different vascular cells.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47573098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P.57 Acetylsalicylic Acid Reduces Passive Aortic Wall Stiffness and Cardiac Remodelling in a Mouse Model of Advanced Atherosclerosis P.57乙酰水杨酸降低晚期动脉粥样硬化小鼠模型中被动主动脉壁硬度和心脏重塑
IF 0.6 4区 医学
Artery Research Pub Date : 2020-12-01 DOI: 10.2991/artres.k.201209.067
L. Roth, W. Martinet, G. D. Meyer
{"title":"P.57 Acetylsalicylic Acid Reduces Passive Aortic Wall Stiffness and Cardiac Remodelling in a Mouse Model of Advanced Atherosclerosis","authors":"L. Roth, W. Martinet, G. D. Meyer","doi":"10.2991/artres.k.201209.067","DOIUrl":"https://doi.org/10.2991/artres.k.201209.067","url":null,"abstract":"","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45906055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P.63 Sarcopenia and Atherosclerotic Occlusive Disease: How Much We Know and What We Need to Know About this Association? 肌少症和动脉粥样硬化闭塞性疾病:我们对这种关联了解多少，我们需要知道什么?
IF 0.6 4区 医学
Artery Research Pub Date : 2020-12-01 DOI: 10.2991/artres.k.201209.072
J. Ferreira, A. Carneiro, P. Cunha, A. Mansilha, I. Vila, C. Cunha, Cristina Silva, A. Longatto-Filho, M. Correia-Neves, Gustavo Soutinho, Luís Meira-Machado, A. Mesquita, J. Cotter
{"title":"P.63 Sarcopenia and Atherosclerotic Occlusive Disease: How Much We Know and What We Need to Know About this Association?","authors":"J. Ferreira, A. Carneiro, P. Cunha, A. Mansilha, I. Vila, C. Cunha, Cristina Silva, A. Longatto-Filho, M. Correia-Neves, Gustavo Soutinho, Luís Meira-Machado, A. Mesquita, J. Cotter","doi":"10.2991/artres.k.201209.072","DOIUrl":"https://doi.org/10.2991/artres.k.201209.072","url":null,"abstract":"1Vascular Surgery DepartmentHospital da Senhora da Oliveira 2Life and Health Science Research Institute (ICVS), School of Medicine, University of Minho 3ICVS/3B’s-PT Government Associate Laboratory 4Radiology DepartmentULSAM 5Medicine DepartmentHospital da Senhora da Oliveira 6Center for the Research and Treatment of Arterial Hypertension and Cardiovascular Risk, Internal Medicine DepartmentHospital da Senhora da Oliveira 7Faculdade de Medicina da Universidade do Porto 8Vascular Surgery Department Hospital de São João 9ICVS/3B’s-PT Government Associate Laboratory 10Department of Pathology (LIM-14), University of São Paulo School of Medicine 11Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos 12Institute of Public Health of the University of Porto (ISPUP)-University of Porto 13Centre of Molecular and Environmental Biology & Department of Mathematics-University of Minho","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47596845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radial Pulse Wave Analysis in Young Male Elite Athletes 青年男性优秀运动员的径向脉搏波分析
IF 0.6 4区 医学
Artery Research Pub Date : 2020-12-01 DOI: 10.2991/artres.k.201208.001
F. Clara, J. Alfie, Gustavo Blanco, Cecilia Resina, Meschino Gustavo, M. Fita
{"title":"Radial Pulse Wave Analysis in Young Male Elite Athletes","authors":"F. Clara, J. Alfie, Gustavo Blanco, Cecilia Resina, Meschino Gustavo, M. Fita","doi":"10.2991/artres.k.201208.001","DOIUrl":"https://doi.org/10.2991/artres.k.201208.001","url":null,"abstract":"Intensive training produces remarkable changes in the cardiovascular system. There are two general types of intensive training: endurance training, and strength training. Endurance training is based on developing moderate effort for a long time, improving the capacity of the aerobic system. In strength training, very intense efforts are developed for a short time, stimulating muscle development and anaerobic metabolism. The effects of training on the cardiovascular system are diverse, and would depend on its type, intensity, and duration.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46594831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
P.40 Ambulatory Measurement of Carotid Stiffness with a Novel Accelerometric System P.40用新型加速度计系统动态测量颈动脉硬度
IF 0.6 4区 医学
Artery Research Pub Date : 2020-12-01 DOI: 10.2991/artres.k.201209.052
R. Arathy, P. Nabeel, J. Jayaraj, V. Abhidev, S. Mohanasankar
{"title":"P.40 Ambulatory Measurement of Carotid Stiffness with a Novel Accelerometric System","authors":"R. Arathy, P. Nabeel, J. Jayaraj, V. Abhidev, S. Mohanasankar","doi":"10.2991/artres.k.201209.052","DOIUrl":"https://doi.org/10.2991/artres.k.201209.052","url":null,"abstract":"Purpose: Arterial stiffness is a well-established marker for cardiovascular health assessment. Current methods rely on expensive imaging systems and specialised operators to perform local stiffness evaluation from the common carotid artery (CCA) and cannot be used for ambulatory monitoring in chronic disease management. In this study, we compare the performance of a novel accelerometric system, which performs ambulatory non-invasive CCA stiffness measurement, against an ultrasoundbased stiffness monitor.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41755412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P.24 Factors Associated with Premature Vascular Aging in Patients with Arterial Hypertension P.24高血压患者血管过早衰老的相关因素
IF 0.6 4区 医学
Artery Research Pub Date : 2020-12-01 DOI: 10.2991/artres.k.201209.037
I. V. Melekhina, E. G. Medvedeva, S. V. Ivanova, E. Yushchuk, E. Trush
{"title":"P.24 Factors Associated with Premature Vascular Aging in Patients with Arterial Hypertension","authors":"I. V. Melekhina, E. G. Medvedeva, S. V. Ivanova, E. Yushchuk, E. Trush","doi":"10.2991/artres.k.201209.037","DOIUrl":"https://doi.org/10.2991/artres.k.201209.037","url":null,"abstract":"Methods: The study included 61 patients (29 men, 32 women) with 1–2 grade AH without cardiovascular complications, aged 40 to 60 years, of which 28 (45.9%) had type 2 diabetes. The duration of AH was 5.0 [2.0; 10.0] years, type 2 diabetes 2.0 [1.0; 4.0] years. The assessment of vascular stiffness using cardio-ankle vascular index (CAVI) and vascular age (VA) was performed by volumetric sphygmography (VaSera-1500). All patients were divided into 2 groups: with normal VA (the passport age corresponds to the VA, n = 35) and premature vascular aging (the VA is higher than the passport age, n = 26).","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46398861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P.42 The Effects of Chemotherapy on Arterial Stiffness in Patients with Hodgkin Lymphoma P.42化疗对霍奇金淋巴瘤患者动脉硬化的影响
IF 0.6 4区 医学
Artery Research Pub Date : 2020-12-01 DOI: 10.2991/artres.k.201209.054
C. Anagnostopoulos, S. Giannouli, N. Ioakimidis, P. Kafouris, I. Koutagiar, A. Sioni, E. Solomou, D. Terentes-Printzios, D. Tousoulis, C. Vlachopoulos
{"title":"P.42 The Effects of Chemotherapy on Arterial Stiffness in Patients with Hodgkin Lymphoma","authors":"C. Anagnostopoulos, S. Giannouli, N. Ioakimidis, P. Kafouris, I. Koutagiar, A. Sioni, E. Solomou, D. Terentes-Printzios, D. Tousoulis, C. Vlachopoulos","doi":"10.2991/artres.k.201209.054","DOIUrl":"https://doi.org/10.2991/artres.k.201209.054","url":null,"abstract":"1Hippokration General Hospital, 1st Cardiology Department, Athens Medical School 2Academy of Athens Biomedical Research Foundation, Center for Experimental Surgery, Clinical and Translational Research, Biomedical Research Foundation 3Academy of Athens Biomedical Research Foundation, Center of Systems Biology 4Hippokration General Hospital, Department of Hematology 5Academy of Athens Biomedical Research Foundation, Center of Systems Biology","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43665584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P.22 Mortality in 98 Type 1 Diabetes Mellitus (T1DM) and Type 2 Diabetes Mellitus (T2DM) Individuals Presenting to a Specialist Podiatry Clinic: Foot Ulcer Location is an Independent Risk Determinant P.22 98例就诊于专科足病诊所的1型糖尿病(T1DM)和2型糖尿病(T2DM)患者的死亡率:足部溃疡位置是一个独立的风险决定因素
IF 0.6 4区 医学
Artery Research Pub Date : 2020-12-01 DOI: 10.2991/artres.k.201209.035
Heather Schofield, S. Haycocks, A. Robinson, S. Anderson, A. Heald
{"title":"P.22 Mortality in 98 Type 1 Diabetes Mellitus (T1DM) and Type 2 Diabetes Mellitus (T2DM) Individuals Presenting to a Specialist Podiatry Clinic: Foot Ulcer Location is an Independent Risk Determinant","authors":"Heather Schofield, S. Haycocks, A. Robinson, S. Anderson, A. Heald","doi":"10.2991/artres.k.201209.035","DOIUrl":"https://doi.org/10.2991/artres.k.201209.035","url":null,"abstract":"Results: Seventeen people (17) had type 1 diabetes mellitus (T1DM), and 81 had type 2 diabetes mellitus (T2DM). 31 were women. The mean age (range) was 63.6 (28–90) years with maximum diabetes duration 45 years. Mean HbA1c was 72 (95% CI: 67–77) mmol/mol. 97% had neuropathy (International Working Group on the Diabetic Foot (IWGDF) monofilament) [2]. 62% had vascular insufficiency (Doppler studies). 69% of ulcers were forefoot and 23% of ulcers were hind foot in location. 40/98 (39.2%) died in follow-up with 27% of death certificates including sepsis (not foot-related) and 35% renal failure as cause of death. Multivariate regression analysis indicated a 6.3 (95% CI: 3.9–8.1) fold increased risk of death with hind foot ulcer, independent of age/BMI/gender/HbA1c/eGFR/total cholesterol level.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48039557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P.32 Non-Invasive Measures of Arteriosclerosis Across Childhood and Adolescence: Insights Into the Natural History of Disease P.32儿童和青少年动脉硬化的无创测量:对疾病自然史的洞察
IF 0.6 4区 医学
Artery Research Pub Date : 2020-12-01 DOI: 10.2991/artres.k.201209.045
Reeja F. Nasir, T. Y. Cai, Alice Meroni, M. Skilton
{"title":"P.32 Non-Invasive Measures of Arteriosclerosis Across Childhood and Adolescence: Insights Into the Natural History of Disease","authors":"Reeja F. Nasir, T. Y. Cai, Alice Meroni, M. Skilton","doi":"10.2991/artres.k.201209.045","DOIUrl":"https://doi.org/10.2991/artres.k.201209.045","url":null,"abstract":"Objectives: Non-invasive methodologies for assessing arteriosclerosis, including carotid intimal-medial thickness (cIMT) for assessing subclinical atherosclerosis and carotid-femoral pulse wave velocity (cfPWV) for measuring arterial stiffness, are well established and validated in adults [1, 2]. However, they are less well-described in children. Alternative methodologies, such as aortic IMT (aIMT), may be more appropriate in children provided the natural history of atherosclerotic disease [3]. Previous studies have predominantly applied these methodologies in a narrow age-range of children; methodological differences between studies make inter-study comparison of absolute values difficult. Therefore, we aimed to assess the severity of arteriosclerosis across childhood and adolescence using standardised application of age-appropriate and established methodologies.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45166633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P.14 Transcranial Colour Duplex Reveals Haemodynamically Significant Venous Flow Alterations Following Resection of Arteriovenous Malformation of the Brain 经颅彩色双工显示脑动静脉畸形切除术后显著的血流动力学改变
IF 0.6 4区 医学
Artery Research Pub Date : 2020-12-01 DOI: 10.2991/artres.k.201209.027
K. Busch, A. Davidson, M. Butlin, A. Avolio, H. Kiat
{"title":"P.14 Transcranial Colour Duplex Reveals Haemodynamically Significant Venous Flow Alterations Following Resection of Arteriovenous Malformation of the Brain","authors":"K. Busch, A. Davidson, M. Butlin, A. Avolio, H. Kiat","doi":"10.2991/artres.k.201209.027","DOIUrl":"https://doi.org/10.2991/artres.k.201209.027","url":null,"abstract":"Background: Resection of a brain arteriovenous malformation (bAVM) can impose several post-operative challenges including postoperative haemorrhage (POH) [1]. The mechanism of such complications remains controversial although deliberately inducing hypotension has proven successful for POH prevention [2]. Daily non-invasive monitoring for patients may be useful in predicting POH. Transcranial color duplex (TCCD) and central aortic pressures (CAP) can be derived non-invasively providing pressure and haemodynamic measurements. These techniques may provide valuable insight into the process of vessel remodeling following bAVM resection.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47050224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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