Arquivos Brasileiros de Cardiologia最新文献_第7页

Determining Percentiles of Atherosclerotic Cardiovascular Risk According to Sex and Age in a Healthy Brazilian Population. 巴西健康人群中按性别和年龄确定动脉粥样硬化性心血管风险的百分位数

IF 2.6 4区医学

Arquivos Brasileiros de Cardiologia Pub Date : 2023-06-01 DOI: 10.36660/abc.20220552

Fernando Yue Cesena, Nea Miwa Kashiwagi, Carlos Andre Minanni, Raul D Santos

{"title":"Determining Percentiles of Atherosclerotic Cardiovascular Risk According to Sex and Age in a Healthy Brazilian Population.","authors":"Fernando Yue Cesena, Nea Miwa Kashiwagi, Carlos Andre Minanni, Raul D Santos","doi":"10.36660/abc.20220552","DOIUrl":"https://doi.org/10.36660/abc.20220552","url":null,"abstract":"Background: Expressing the risk of atherosclerotic cardiovascular disease (ASCVD) as percentiles of the distribution according to sex and age may provide a better perception of the risk.Objectives: To determine percentiles of the 10-year ASCVD risk distribution according to sex and age in a sample of the Brazilian population; to characterize individuals at low 10-year risk but high risk percentile.Methods: We analyzed individuals aged 40 to 75 years who underwent routine health evaluations from 2010 to 2020. Persons with known clinical ASCVD, diabetes mellitus, chronic kidney disease, or LDL-cholesterol ≥ 190 mg/dL were excluded. The 10-year ASCVD risk was calculated by the ACC/AHA pooled cohort equations. Local polynomial regression was used to determine risk percentiles. Two-sided p-values < 0.050 were considered statistically significant.Results: Our sample comprised 54,145 visits (72% male, median age [interquartile range] 48 [43, 53] years). We constructed sex-specific graphs plotting age against ASCVD risk corresponding to the 10th, 25th, 50th, 75th, and 90th percentiles. Most males up to 47 years and females up to 59 years above the 75th percentile had a 10-year risk < 5%. Individuals at low 10-year risk and risk percentile ≥ 75th had a high prevalence of excess weight and median (interquartile range) LDL-cholesterol levels 136 (109, 158) mg/dL (males) and 126 (105, 147) mg/dL (females).Conclusions: We established ASCVD risk percentiles according to sex and age in a large sample of the Brazilian population. This approach may increase risk awareness and help identify younger persons at low 10-year risk who may benefit from more aggressive risk factor control.","PeriodicalId":8399,"journal":{"name":"Arquivos Brasileiros de Cardiologia","volume":"120 6","pages":"e20220552"},"PeriodicalIF":2.6,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344368/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10547734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Comparison of Cardioplegic Solutions in Coronary Bypass Surgery Over Autophagy and Apoptosis Mechanisms. 冠状动脉搭桥术中自噬和细胞凋亡机制下心脏截瘫解决方案的比较。

IF 2.6 4区医学

Arquivos Brasileiros de Cardiologia Pub Date : 2023-06-01 DOI: 10.36660/abc.20220479

Elif Funda Sener, Zuhal Hamurcu, Serpil Taheri, Reyhan Tahtasakal, Nesrin Delibasi, Deniz Elcik, Ecmel Mehmetbeyoglu, Aydin Tuncay, Fatma Dal, Keziban Korkmaz Bayram, Isın Gunes, Omer Naci Emirogullari

{"title":"Comparison of Cardioplegic Solutions in Coronary Bypass Surgery Over Autophagy and Apoptosis Mechanisms.","authors":"Elif Funda Sener, Zuhal Hamurcu, Serpil Taheri, Reyhan Tahtasakal, Nesrin Delibasi, Deniz Elcik, Ecmel Mehmetbeyoglu, Aydin Tuncay, Fatma Dal, Keziban Korkmaz Bayram, Isın Gunes, Omer Naci Emirogullari","doi":"10.36660/abc.20220479","DOIUrl":"https://doi.org/10.36660/abc.20220479","url":null,"abstract":"Background: Coronary artery disease (CAD) due to myocardial ischemia causes permanent loss of heart tissue.Objectives: We aimed to demonstrate the possible damage to the myocardium at the molecular level through the mechanisms of autophagy and apoptosis in coronary bypass surgery patients.Methods: One group was administered a Custodiol cardioplegia solution, and the other group was administered a Blood cardioplegia solution. Two myocardial samples were collected from each patient during the operation, just before cardiac arrest and after the aortic cross-clamp was released. The expressions of autophagy and apoptosis markers were evaluated. The level of statistical significance adopted was 5%.Results: The expression of the BECLIN gene was significant in the myocardial tissues in the BC group (p=0.0078). CASPASE 3, 8, and 9 gene expression levels were significantly lower in the CC group. Postoperative TnT levels were significantly different between the groups (p=0.0072). CASPASE 8 and CASPASE 9 gene expressions were similar before and after aortic cross-clamping (p=0.8552, p=0.8891). In the CC group, CASPASE 3, CASPASE 8, and CASPASE 9 gene expression levels were not found to be significantly different in tissue samples taken after aortic cross-clamping (p=0.7354, p=0.0758, p=0.4128, respectively).Conclusions: With our findings, we believe that CC and BC solutions do not have a significant difference in terms of myocardial protection during bypass operations.","PeriodicalId":8399,"journal":{"name":"Arquivos Brasileiros de Cardiologia","volume":"120 7","pages":"e20220479"},"PeriodicalIF":2.6,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10364987/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10548223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Atypical Non-Cardiac Presentation of Hypertrophic Cardiomyopathy. 肥厚性心肌病的非典型非心脏表现。

IF 2.6 4区医学

Arquivos Brasileiros de Cardiologia Pub Date : 2023-06-01 DOI: 10.36660/abc.20220933

André Alexandre, Carla Roque, Isabel Sá, João Silveira, Severo Torres

{"title":"An Atypical Non-Cardiac Presentation of Hypertrophic Cardiomyopathy.","authors":"André Alexandre, Carla Roque, Isabel Sá, João Silveira, Severo Torres","doi":"10.36660/abc.20220933","DOIUrl":"https://doi.org/10.36660/abc.20220933","url":null,"abstract":"Supplementary Video 2) revealed moderate asymmetric septal LV hypertrophy (interventricular septum thickness 14 mm, posterior wall thickness 9 mm), mildly reduced LV ejection fraction (45%), apical akinesia, and an image suggestive of thrombus, explaining the cardioembolic stroke. Cardiovascular magnetic resonance (CMR) confirmed the diagnosis of HCM, with extensive apical fibrosis and akinesia of the apical segments, outlining an apical aneurysm and thrombus (Figure 2). Coronary angiography was performed regarding the possibility of concomitant ischemic heart disease, ruling out obstructive coronary artery disease. Serologic examination for Trypanosoma cruzi was negative. The patient was started on systemic anticoagulation with a vitamin K antagonist (VKA). Considering the diagnosis of HCM with extensive apical fibrosis and an apical aneurism, after patient-shared decision-making, it was decided to place a subcutaneous implantable cardioverter-defibrillator (S-ICD). He was discharged after 18 days. At the 1-year follow-up, control transthoracic echocardiography showed complete resolution of the apical thrombus, and the patient remained on systemic anticoagulation with a VKA. HCM is a relatively common but still underdiagnosed cardiac disease. 1 This case illustrates an extremely rare and life-threatening non-cardiac first presentation of HCM. This unusual HCM phenotype with a thin-walled, scarred LV apical aneurysm is associated with an increased risk of sudden arrhythmic death and thromboembolic stroke. 2,3","PeriodicalId":8399,"journal":{"name":"Arquivos Brasileiros de Cardiologia","volume":"120 6","pages":"e20220933"},"PeriodicalIF":2.6,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344080/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10530233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Are We Reaching the End of the Evolutionary Road to Metallic Drug-Eluting Stents? Which 4th Generation Stents Do We Need? 金属药物洗脱支架的进化之路是否已经走到了尽头?我们需要哪种第四代支架?

IF 2.6 4区医学

Arquivos Brasileiros de Cardiologia Pub Date : 2023-06-01 DOI: 10.36660/abc.20230302

Manuel Sousa Almeida

引用次数: 0

Could Patients At Low Cardiovascular Risk Be Better Stratified? 低心血管风险患者是否可以更好地分层?

IF 2.6 4区医学

Arquivos Brasileiros de Cardiologia Pub Date : 2023-06-01 DOI: 10.36660/abc.20230310

Francisco Antonio Helfenstein Fonseca, Maria Cristina Izar

引用次数: 0

Incidence and Morphological Study of Myocardial Bridge in the State of Ceará: A Cadaveric Study. 心肌桥在心肌缺血状态下的发生率和形态学研究:一项尸体研究。

IF 2.6 4区医学

Arquivos Brasileiros de Cardiologia Pub Date : 2023-06-01 DOI: 10.36660/abc.20220460

Jalles Dantas de Lucena, Hudson Martins de Brito, João Victor Souza Sanders, Jonathan Barros Cavalcante, Michelly Carneiro Collyer, Cecília de Lima Leite, Helson Freitas da Silveira, Julio Cesar Campos Ferreira Filho

{"title":"Incidence and Morphological Study of Myocardial Bridge in the State of Ceará: A Cadaveric Study.","authors":"Jalles Dantas de Lucena, Hudson Martins de Brito, João Victor Souza Sanders, Jonathan Barros Cavalcante, Michelly Carneiro Collyer, Cecília de Lima Leite, Helson Freitas da Silveira, Julio Cesar Campos Ferreira Filho","doi":"10.36660/abc.20220460","DOIUrl":"https://doi.org/10.36660/abc.20220460","url":null,"abstract":"Background: Myocardial bridges (MB) are anatomical anomalies with possible clinical repercussions; hence, their understanding deserves attention.Objective: To determinate the prevalence and characterize MB in human hearts from the state of Ceará. Methods: Fifty hearts of adult human cadavers from the Medicine School of Federal University of Ceará, Brazil. The hearts were dissected to identify MBs that pass over part of the coronary artery. The segment of the artery (proximal, middle, and distal) with a bridge was identified. The external diameter of the artery at the proximal and distal points of the MB was measured. The length and thickness of the MB were also measured with an electronic caliper. The muscle index (MMI) of the MB was calculated as the product of length and thickness expressed in millimeters. The significance level adopted in the statistical analysis was 5%.Results: MB was confirmed in 40% of sample. Approximately one third of the sample had only 1 MB. MB was most frequently found over the anterior interventricular branch of the left coronary artery (59.25%, p=0.02), and its prevalence in other branches was much lower (22.23%). The most affected segments of arteries were the superior (44.44%) and medium (40.74%). The mean diameter of arteries proximal to the MB was 2.38±0.97mm (range=0.78-5.15mm), and the diameter distal to the MB was 1.71±0.75mm (range=0.42-3.58mm). The length was measured as mean=8.55±5.27mm, while the mean thickness was 0.89±0.33mm.Conclusion: A high prevalence of MB is more likely to affect the left coronary artery system with larger MMI than other affected branches.","PeriodicalId":8399,"journal":{"name":"Arquivos Brasileiros de Cardiologia","volume":"120 7","pages":"e20220460"},"PeriodicalIF":2.6,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10365010/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10548222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Construction and Validation of a Protocol Targeting Patients on Oral Anticoagulation with Warfarin. 构建并验证针对华法林口服抗凝药患者的方案。

IF 2.6 4区医学

Arquivos Brasileiros de Cardiologia Pub Date : 2023-06-01 DOI: 10.36660/abc.20220576

Hannah Cardoso Barbosa, Heloisa de Carvalho Torres, João Antônio de Queiroz Oliveira, Rebeca Priscilla de Melo Santos, Josiane Moreira da Costa, Leonardo Gonçalves Miranda, Adriana Silvina Pagano, Marcus Fernando da Silva Praxedes, Maria Auxiliadora Parreiras Martins

{"title":"Construction and Validation of a Protocol Targeting Patients on Oral Anticoagulation with Warfarin.","authors":"Hannah Cardoso Barbosa, Heloisa de Carvalho Torres, João Antônio de Queiroz Oliveira, Rebeca Priscilla de Melo Santos, Josiane Moreira da Costa, Leonardo Gonçalves Miranda, Adriana Silvina Pagano, Marcus Fernando da Silva Praxedes, Maria Auxiliadora Parreiras Martins","doi":"10.36660/abc.20220576","DOIUrl":"10.36660/abc.20220576","url":null,"abstract":"Background: Warfarin is an oral anticoagulant that is very useful in preventing thromboembolism, though it is considered a drug with a high risk of causing adverse events. Considering the practical challenges in controlling oral anticoagulation, the patients on warfarin could benefit from educational strategies aimed at behavioral changes, active participation in self-care, and adherence to drug therapy.Objective: The aim was to construct and validate the EmpoderACO protocol for behavioral changes in warfarin patients.Methods: The methodological steps were: definition of concepts and domains of self-care, identification of objectives, construction and selection of items, assessment of content validity, and pre-test in the target population.Results: Relevance, adequacy, clarity, and internal reliability of the instrument's items were assessed by a multidisciplinary judges committee (JC) through the E-surv web platform, obtaining an average agreement of ≥0.91. The understanding of the instrument measured by the target population revealed adequate clarity with a coefficient average of 0.96.Conclusion: EmpoderACO can aid in qualifying the communication process between medical professionals and patients, as well as in improving adherence to both treatment and clinical outcomes, and can be replicated in healthcare settings.","PeriodicalId":8399,"journal":{"name":"Arquivos Brasileiros de Cardiologia","volume":"120 6","pages":"e20220576"},"PeriodicalIF":2.6,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344350/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10547737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Carcinoid Heart Disease: A Case Report and Literature Review. 类癌性心脏病1例报告及文献复习。

IF 2.6 4区医学

Arquivos Brasileiros de Cardiologia Pub Date : 2023-06-01 DOI: 10.36660/abc.20220245

Isabela Bispo Santos da Silva Costa, Edielle de Sant Anna Melo, Armando Furtado, Juliana Barbosa Sobral-Alves, Stephanie Itala Rizk, Luiz Alberto Benvenuti, Carlos E Rochitte, Carlos Manuel de Almeida Brandão, Pablo Maria Pomarentzeff, Cristina Salvadori Bittar, Filomena Regina Barbosa Gomes Galas, José Otavio Costa Auler Junior, Paulo Marcelo Gehm Hoff, Roberto Kalil Filho, Fabio Biscegli Jatene, Ludhmila Abrahão Hajjar

{"title":"Carcinoid Heart Disease: A Case Report and Literature Review.","authors":"Isabela Bispo Santos da Silva Costa, Edielle de Sant Anna Melo, Armando Furtado, Juliana Barbosa Sobral-Alves, Stephanie Itala Rizk, Luiz Alberto Benvenuti, Carlos E Rochitte, Carlos Manuel de Almeida Brandão, Pablo Maria Pomarentzeff, Cristina Salvadori Bittar, Filomena Regina Barbosa Gomes Galas, José Otavio Costa Auler Junior, Paulo Marcelo Gehm Hoff, Roberto Kalil Filho, Fabio Biscegli Jatene, Ludhmila Abrahão Hajjar","doi":"10.36660/abc.20220245","DOIUrl":"https://doi.org/10.36660/abc.20220245","url":null,"abstract":"Isabela Bispo Santos da Silva Costa,1,2,3 Edielle de Sant`Anna Melo,1 Armando Furtado,2 Juliana Barbosa SobralAlves,1,2 Stephanie Itala Rizk,1,2 Luiz Alberto Benvenuti,2 Carlos E. Rochitte,2 Carlos Manuel de Almeida Brandão,2 Pablo Maria Pomarentzeff,2 Cristina Salvadori Bittar,1,2 Filomena Regina Barbosa Gomes Galas,2,3 José Otavio Costa Auler Junior,2 Paulo Marcelo Gehm Hoff,1 Roberto Kalil Filho,2,3 Fabio Biscegli Jatene,2 Ludhmila Abrahão Hajjar1,2 Universidade de São Paulo Instituto do Câncer do Estado de São Paulo,1 São Paulo, SP – Brasil Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo,2 São Paulo, SP – Brasil Hospital Sírio-Libanês,3 São Paulo, SP – Brasil","PeriodicalId":8399,"journal":{"name":"Arquivos Brasileiros de Cardiologia","volume":"120 6","pages":"e20220245"},"PeriodicalIF":2.6,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10365021/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10548215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New Technique for Preserving Cephalic Vein Flow in Pacemaker Implantation Ipsilateral to Arteriovenous Fistula. 动静脉瘘同侧起搏器植入中保留头静脉血流的新技术。

IF 2 4区医学

Arquivos Brasileiros de Cardiologia Pub Date : 2023-06-01 DOI: 10.36660/abc.20220926

Mafalda Carrington, Pedro Silvério António, Natacha Rodrigues, Afonso Nunes-Ferreira, Ana Bernardes, Fausto J Pinto, João de Sousa, Pedro Marques

引用次数: 0

Triglycerides-Glucose İndex and Coronary Slow Flow: A New Diagnostic Tool? 甘油三酯-葡萄糖İndex与冠状动脉慢血流:一种新的诊断工具?

IF 2.6 4区医学

Arquivos Brasileiros de Cardiologia Pub Date : 2023-06-01 DOI: 10.36660/abc.20230373

Maria Cristina Costa de Almeida, Marildes Luiza de Castro

引用次数: 0