Arquivos Brasileiros de Cardiologia最新文献_第10页

Brazilian Interventional Cardiology and Chronic Coronary Occlusions: Where Are We? 巴西介入心脏病学和慢性冠状动脉闭塞:我们在哪里?

IF 2.6 4区医学

Arquivos Brasileiros de Cardiologia Pub Date : 2023-05-01 DOI: 10.36660/abc.20230172

José Mariani Junior

引用次数: 0

SLC26A4-AS1 Aggravates AngII-induced Cardiac Hypertrophy by Enhancing SLC26A4 Expression. SLC26A4-AS1通过增强SLC26A4的表达加重AngII诱导的心脏肥大。

IF 2.6 4区医学

Arquivos Brasileiros de Cardiologia Pub Date : 2023-04-21 eCollection Date: 2023-01-01 DOI: 10.36660/abc.20210933

Xiaoliang Han, Chao Li, Qinjiong Ji, Ling Zhang, Xiaofei Xie, Huijuan Shang, Hong Ye

{"title":"SLC26A4-AS1 Aggravates AngII-induced Cardiac Hypertrophy by Enhancing SLC26A4 Expression.","authors":"Xiaoliang Han, Chao Li, Qinjiong Ji, Ling Zhang, Xiaofei Xie, Huijuan Shang, Hong Ye","doi":"10.36660/abc.20210933","DOIUrl":"10.36660/abc.20210933","url":null,"abstract":"Background: It has been reported that solute carrier family 26 members 4 antisense RNA 1 (SLC26A4-AS1) is highly related to cardiac hypertrophy.Objective: This research aims to investigate the role and specific mechanism of SLC26A4-AS1 in cardiac hypertrophy, providing a novel marker for cardiac hypertrophy treatment.Methods: Angiotensin II (AngII) was infused into neonatal mouse ventricular cardiomyocytes (NMVCs) to induce cardiac hypertrophy. Gene expression was detected by quantitative real-time PCR (RT-qPCR). Protein levels were evaluated via western blot. Functional assays analyzed the role of SLC26A4-AS1. The mechanism of SLC26A4-AS1 was assessed by RNA-binding protein immunoprecipitation (RIP), RNA pull-down, and luciferase reporter assays. The P value <0.05 was identified as statistical significance. Student's t-test evaluated the two-group comparison. The difference between different groups was analyzed by one-way analysis of variance (ANOVA).Results: SLC26A4-AS1 is upregulated in AngII-treated NMVCs and promotes AngII-induced cardiac hypertrophy. SLC26A4-AS1 regulates its nearby gene solute carrier family 26 members 4 (SLC26A4) via functioning as a competing endogenous RNA (ceRNA) to modulate the microRNA (miR)-301a-3p and miR-301b-3p in NMVCs. SLC26A4-AS1 promotes AngII-induced cardiac hypertrophy via upregulating SLC26A4 or sponging miR-301a-3p/miR-301b-3p.Conclusion: SLC26A4-AS1 aggravates AngII-induced cardiac hypertrophy via sponging miR-301a-3p or miR-301b-3p to enhance SLC26A4 expression.","PeriodicalId":8399,"journal":{"name":"Arquivos Brasileiros de Cardiologia","volume":"120 4","pages":"e20210933"},"PeriodicalIF":2.6,"publicationDate":"2023-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10263427/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10175552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Association between Mortality from Chronic Noncommunicable Diseases and Human Development Index in Brazil between 1980 and 2019. 1980年至2019年巴西慢性非传染性疾病死亡率与人类发展指数之间的关系

IF 2.3 4区医学

Arquivos Brasileiros de Cardiologia Pub Date : 2023-04-21 eCollection Date: 2023-01-01 DOI: 10.36660/abc.20211009

Sandra Chagas da Costa Feliciano, Paolo Blanco Villela, Gláucia Maria Moraes de Oliveira

{"title":"Association between Mortality from Chronic Noncommunicable Diseases and Human Development Index in Brazil between 1980 and 2019.","authors":"Sandra Chagas da Costa Feliciano, Paolo Blanco Villela, Gláucia Maria Moraes de Oliveira","doi":"10.36660/abc.20211009","DOIUrl":"10.36660/abc.20211009","url":null,"abstract":"Background: Chronic noncommunicable diseases (CNCDs) caused more than 734,000 deaths (55% of all deaths) in Brazil in 2019, with an important socioeconomic impact.Objectives: To analyze the mortality rates from CNCDs in Brazil from 1980 to 2019 and their association with socioeconomic indicators.Method: This was a descriptive, time-series study of deaths from CNCDs in Brazil from 1980 to 2019. Data on the annual frequencies of deaths and on population were obtained from the Department of Informatics of the Brazilian Unified Health System. Crude and standardized mortality rates per 100,000 inhabitants were estimated using the direct method (Brazilian population in 2000). The quartiles of each CNCD were calculated, where a quartile change, due to an increase in mortality rate, was represented by a chromatic gradient. The Municipal Human Development Index (MHDI) of each Brazilian federative unit was extracted from the Atlas Brasil website and correlated with the rates of CNCD mortality.Results: There was a reduction in mortality rates due to diseases of the circulatory system during the period, except in the Northeast Region. There was also an increase in mortality from neoplasia and diabetes, while the rates of chronic respiratory diseases showed little variation. There was an inverse correlation between the federative units with greater reduction in CNCD mortality rates and the MHDI.Conclusions: The observed decrease in mortality due to diseases of the circulatory system may reflect an improvement in socioeconomic indicators in Brazil during the period. The increase in mortality rates due to neoplasms is probably related to the aging of the population. The higher mortality rates of diabetes seem to be associated with an increase in the prevalence of obesity in Brazilian women.","PeriodicalId":8399,"journal":{"name":"Arquivos Brasileiros de Cardiologia","volume":"120 4","pages":"e20211009"},"PeriodicalIF":2.3,"publicationDate":"2023-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10263428/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10547193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Challenge of Making Cardiac Resonance a Global Reality. 使心脏共振成为全球现实的挑战。

IF 2.6 4区医学

Arquivos Brasileiros de Cardiologia Pub Date : 2023-04-21 DOI: 10.36660/abc.20230187

Hélder Jorge Andrade Gomes, Alcides Rocha de Figueredo Junior

引用次数: 0

Left Ventricular Mechanics: Untwisting the Pathways of the Cardiovascular Response to Exercise. 左心室力学:解开心血管对运动反应的途径。

IF 2.6 4区医学

Arquivos Brasileiros de Cardiologia Pub Date : 2023-04-21 DOI: 10.36660/abc.20230181

Eduardo M Vilela, Ricardo Fontes-Carvalho

{"title":"Left Ventricular Mechanics: Untwisting the Pathways of the Cardiovascular Response to Exercise.","authors":"Eduardo M Vilela, Ricardo Fontes-Carvalho","doi":"10.36660/abc.20230181","DOIUrl":"https://doi.org/10.36660/abc.20230181","url":null,"abstract":"Correspondência: Eduardo M. Vilela • Serviço de Cardiologia, Centro Hospitalar de Vila Nova de Gaia/Espinho – Rua Conceição Fernandes, 4434-502, Vila Nova de Gaia – Portugal E-mail: eduardomvilela@gmail.com Palavras-chave Doenças Cardiovasculares/prevenção e controle; Doença Arterial Coronariana; Diagnóstico por Imagem/métodos; Ecocardiografia/métodos A doença cardiovascular (DCV) é uma das principais causas de morbimortalidade, sendo a doença arterial coronariana (DAC) uma de suas apresentações mais desafiadoras.1 Ao longo dos anos, diversas estratégias permitiram melhorias marcantes em sua gestão. O exercício físico (um componente central dos programas de reabilitação cardíaca) é atualmente uma pedra angular das estratégias contemporâneas abrangentes de prevenção secundária.2 Embora os benefícios do exercício físico tenham sido extensivamente descritos na presença de DAC, as inúmeras vias mecanísticas pelas quais essa intervenção exerce seus diversos efeitos não foram totalmente elucidadas.3,4 De fato, embora seu impacto positivo na capacidade funcional tenha sido destacado, o papel relativo do treinamento físico na função sistólica mostrou alguma variabilidade em diferentes estudos.4,5 Sem deixar de ter em consideração o fato de as diferenças nos desenhos dos programas e das populações em estudo poderem, pelo menos em parte, ajudar a explicar algumas dessas divergências, o estudo dos mecanismos pelos quais o exercício pode ter impacto na função cardíaca (nomeadamente no contexto da DAC) continua a ser um tema de grande interesse.","PeriodicalId":8399,"journal":{"name":"Arquivos Brasileiros de Cardiologia","volume":"120 4","pages":"e20230181"},"PeriodicalIF":2.6,"publicationDate":"2023-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10263430/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10547189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Multi-Arterial Grafting in Surgical Coronary Revascularization. The Renewed Quest for Enhanced Outcomes. 外科冠状动脉血运重建中的多动脉移植。提高疗效的新追求。

IF 2 4区医学

Arquivos Brasileiros de Cardiologia Pub Date : 2023-04-07 DOI: 10.36660/abc.20230094

Walter J Gomes

引用次数: 0

Infective Endocarditis: New Spectra, Same Severity. 感染性心内膜炎:新的光谱，相同的严重性。

IF 2.6 4区医学

Arquivos Brasileiros de Cardiologia Pub Date : 2023-04-07 DOI: 10.36660/abc.20230117

Tiago Bignoto

引用次数: 0

Nuclear Cardiology in the Optimization of Resynchronization Therapy: Quo Vadis? 核心脏病学在再同步治疗优化中的应用:现状?

IF 2.6 4区医学

Arquivos Brasileiros de Cardiologia Pub Date : 2023-04-07 DOI: 10.36660/abc.20230136

Gabriel Blacher Grossman

引用次数: 0

Paraoxonase-1 Genotype and Angiogram Positive Coronary Artery Disease. 对氧磷酶-1基因型与冠状动脉造影阳性

IF 2.6 4区医学

Arquivos Brasileiros de Cardiologia Pub Date : 2023-04-07 DOI: 10.36660/abc.20220665

Rujittika Mungmunpuntipantip, Viroj Wiwanitkit

引用次数: 0

Exercise-Based Cardiac Rehabilitation (ECBR): New Frontiers in the Post-Novel Coronavirus. 基于运动的心脏康复(ECBR):后新型冠状病毒的新领域

IF 2.6 4区医学

Arquivos Brasileiros de Cardiologia Pub Date : 2023-04-07 DOI: 10.36660/abc.20230120

Rosane Maria Nery, Antonio Cardoso Dos Santos, Eduardo Lima Garcia

引用次数: 0