C. Sánchez , G. Romero , E. Ontiveros , I. Martínez , L.L. Arroyo Muñoz , M. Mandujano , K.M. Soler-Limón
{"title":"Potenciales evocados visuales y desarrollo en niños con catarata congénita y cirugía después de los cuatro meses de edad","authors":"C. Sánchez , G. Romero , E. Ontiveros , I. Martínez , L.L. Arroyo Muñoz , M. Mandujano , K.M. Soler-Limón","doi":"10.1016/j.oftal.2025.502436","DOIUrl":"10.1016/j.oftal.2025.502436","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Congenital cataract (CC) is a pediatric eye condition that causes low vision and blindness. Despite the possible surgical treatment to avoid disability, it produces a fifth of the world's blind children. Visual Evoked Cortical Potentials (VEP) is an essential procedure for clinical practice to evaluate the visual pathway and cortex; however, there are no reports of VEP in CC cases. The objective was to explore visual function in CC cases treated by surgical removal and lens implantation older than four months of age and their effect on their postoperative development.</div></div><div><h3>Materials and methods</h3><div>Prospective longitudinal study of 53 CC cases. VEP were done under standard techniques, exploring mono and binocular responses, obtaining waves N1, P1 y N2, and the amplitude of P1. The possible impact on child development was evaluated using Gesell scales.</div></div><div><h3>Results</h3><div>All CC cases, except 6 with associated morbidities, had VEP responses. Before 12 months, they had moderate delays but followed the expected ontogenic reductions during postoperative periods. CC cases with more significant initial alteration obtained higher development quotients.</div></div><div><h3>Conclusions</h3><div>CC cases had VEP responses and had postoperative reductions according to age. Their preoperative developmental delays improved on postoperative period. VEP is useful for assessing the effect of surgery on child development. Although cases were diagnosed and treated late, considering the positive impact in cases younger than 12 months demonstrated that the recovery critical period window is remarkably more extended than the accepted on academic reports. These findings could modify the surgical criterion for treating CC cases, especially in less developed countries.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"101 1","pages":"Article 502436"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146036984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Domínguez García , P. Vázquez Colomo , P. Spang-Valencia , S. Quiñones Garrido , E. Ruiz Bravo-Burguillos
{"title":"Membrana de Descemet retenida tras queratoplastia penetrante con queratoplastia endotelial de la membrana de Descemet previa","authors":"L. Domínguez García , P. Vázquez Colomo , P. Spang-Valencia , S. Quiñones Garrido , E. Ruiz Bravo-Burguillos","doi":"10.1016/j.oftal.2025.07.007","DOIUrl":"10.1016/j.oftal.2025.07.007","url":null,"abstract":"<div><div>Although keratoplasties are key surgical procedures for treating corneal diseases, they may present late complications such as retrocorneal membranes. We present an unusual case following a penetrating keratoplasty (PKP) in a patient with a history of DMEK. This is the case of an 85-year-old woman with a past medical history of DMEK and 2 PKPs due to previous graft failures, who developed a retrocorneal membrane 6 months after the last PKP. A membranectomy was performed. Histological analysis confirmed the presence of retained Descemet's membrane and decreased endothelial cell density. Visual acuity remained stable (0.4–0.63) with no signs of edema. No recurrence was observed. Late retention of Descemet's membrane may result from incomplete descemetorhexis, among other causes. Although asymptomatic, it may require surgery. Close postoperative follow-up is essential.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"100 12","pages":"Pages 802-807"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145623470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Redes sociales y oftalmología en España: un nuevo escenario para pacientes y profesionales","authors":"V. Miralles-Pechuán , J. González Martín-Moro","doi":"10.1016/j.oftal.2025.09.002","DOIUrl":"10.1016/j.oftal.2025.09.002","url":null,"abstract":"","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"100 12","pages":"Pages 749-751"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145623475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reversibilidad de la elipsoiditis sifilítica","authors":"F. Garcia Ibor, N. Ruiz del Rio, A. Caro Ortega","doi":"10.1016/j.oftal.2025.06.008","DOIUrl":"10.1016/j.oftal.2025.06.008","url":null,"abstract":"","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"100 12","pages":"Pages 812-813"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145623473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Morocho, J.P. Aldecoa, G. Fridrich, S. Vivante, N. Gorjovsky
{"title":"Evaluación de la apertura palpebral postintervención de reinserción de la aponeurosis elevadora con abordaje anterior y posterior","authors":"G. Morocho, J.P. Aldecoa, G. Fridrich, S. Vivante, N. Gorjovsky","doi":"10.1016/j.oftal.2025.07.005","DOIUrl":"10.1016/j.oftal.2025.07.005","url":null,"abstract":"<div><h3>Background and objective</h3><div>Levator aponeurosis advancement is a technique used to treat aponeurotic ptosis, which can be performed via anterior (transcutaneous) or posterior (transconjunctival) approach, each with specific advantages. This study aims to evaluate and compare pre- and postoperative eyelid aperture outcomes for both techniques and analyze the rate of over- and undercorrections, contributing to a better understanding of their efficacy and limitations.</div></div><div><h3>Materials and methods</h3><div>We conducted a retrospective study on 62 eyelids with aponeurotic ptosis and good levator function. A total of 32 anterior and 30 posterior approaches were performed, assessing marginal reflex distance 1 (MRD1), eyelid aperture (EA), and their pre- and postoperative variations, along with the rate of over- and undercorrections relative to ideal values.</div></div><div><h3>Results</h3><div>MRD1: Preoperative values for the anterior approach were 1.59<!--> <!-->±<!--> <!-->1.08<!--> <!-->mm, and 0.85<!--> <!-->±<!--> <!-->1.00<!--> <!-->mm for the posterior approach. Improvements were 2.08<!--> <!-->±<!--> <!-->1.59<!--> <!-->mm for the anterior approach and 2.13<!--> <!-->±<!--> <!-->1.32<!--> <!-->mm for the posterior one (p<!--> <!-->><!--> <!-->0.05).</div><div>EA: Improvements were 2.03<!--> <!-->±<!--> <!-->2.15<!--> <!-->mm for the anterior approach and 2.50<!--> <!-->±<!--> <!-->1.66<!--> <!-->mm for the posterior one (p<!--> <!-->><!--> <!-->0.05).</div><div>Ideal MRD1 correction (4<!--> <!-->mm) was achieved in 31.3% of anterior cases vs 20.0% of posterior cases (p<!--> <!-->≈<!--> <!-->0.05).</div><div>Ideal EA correction (10<!--> <!-->mm) was achieved in 18.8% of anterior cases vs 3.3% of posterior cases (p<!--> <!--><<!--> <!-->0.05).</div></div><div><h3>Conclusions</h3><div>Both approaches are effective, but the anterior approach demonstrates higher rates of ideal corrections and fewer undercorrections. The posterior approach was used in lower preoperative DMR1 cases, which may have influenced the results. Selection should be based on the patient's specific characteristics and needs.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"100 12","pages":"Pages 767-774"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145623479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Martínez de la Casa , M. Matilla , J. García Bella , L. Morales , B. Burgos Blasco
{"title":"Análisis de las características biométricas oculares en población mediterránea","authors":"M. Martínez de la Casa , M. Matilla , J. García Bella , L. Morales , B. Burgos Blasco","doi":"10.1016/j.oftal.2025.07.010","DOIUrl":"10.1016/j.oftal.2025.07.010","url":null,"abstract":"<div><h3>Background and Objective</h3><div>The changes of ocular biometric parameters with age have significant clinical implications for intraocular lens (IOL) power calculation and surgical planning. However, few large-sample studies have analyzed this variability in Mediterranean populations with cataract. The objective of the present study is to analyze the biometric characteristics of a large sample with a complete age representation</div></div><div><h3>Material and Methods</h3><div>Retrospective observational study including 5,716 eyes. Axial length (AL), corneal radii (R1 and R2), anterior chamber depth (ACD), central corneal thickness (CCT), white-to-white diameter (WTW), and lens thickness (LT) were analyzed. Linear and polynomial regression models were applied to assess their relationship with age. Adjustments for sex were performed using multiple regression.</div></div><div><h3>Results</h3><div>AL and ACD decreased significantly with age (p <<!--> <!-->0.001), while LT increased exponentially from the sixth decade onwards (p <<!--> <!-->0.001). No relevant changes were observed in CCT or WTW. Males presented greater AL, ACD, and WTW than females (p <<!--> <!-->0.001). Variability increased in older age groups.</div></div><div><h3>Conclusions</h3><div>This study provides detailed and population-specific reference values for the Mediterranean population with cataract. Identifying morphometric patterns associated with ocular aging enables optimized IOL calculation and risk anticipation in elderly patients.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"100 12","pages":"Pages 775-780"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145623478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C.M. Ortega, A.T. Pérez Bello, B.F. Graizman Kohan, M.D. Eraso Quintero, J. Stuart Pennington, F.M. Preto
{"title":"Uveítis asociada a inmunoterapia y su respuesta a monoterapia con difluprednato, a propósito de un caso","authors":"C.M. Ortega, A.T. Pérez Bello, B.F. Graizman Kohan, M.D. Eraso Quintero, J. Stuart Pennington, F.M. Preto","doi":"10.1016/j.oftal.2025.06.012","DOIUrl":"10.1016/j.oftal.2025.06.012","url":null,"abstract":"<div><div>Nivolumab and ipilimumab are immune checkpoint inhibitors widely used for the treatment of metastatic melanoma. They can cause various adverse effects in a significant percentage of treated patients, including uveitis. Symptoms include decreased visual acuity, pain, redness, and photophobia, which typically resolve with appropriate anti-inflammatory therapy. The aim of this work is to report a case of uveitis in a patient on ipilimumab and nivolumab for the treatment of metastatic melanoma, as well as the response to therapy with difluprednate.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"100 12","pages":"Pages 788-792"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145623468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Dominguez García, P. Spang-Valencia, C. Leis-Cofiño, J. Villagrá Lecuona, P. Monreal-Lodeiros, I. Rosa Pérez
{"title":"Valor de los suplementos de vitamina A en el aumento del grosor macular en un paciente con hipovitaminosis A y nictalopía","authors":"L. Dominguez García, P. Spang-Valencia, C. Leis-Cofiño, J. Villagrá Lecuona, P. Monreal-Lodeiros, I. Rosa Pérez","doi":"10.1016/j.oftal.2025.07.004","DOIUrl":"10.1016/j.oftal.2025.07.004","url":null,"abstract":"<div><div>Although vitamin A deficiency is a rare cause of nyctalopia, its detection is crucial since vitamin<!--> <!-->A supplementation can improve vision. This is the case of a 69-year-old woman with progressive night blindness, a past medical history of intestinal surgery, and low vitamin<!--> <!-->A levels. After vitamin<!--> <!-->A treatment, her visual acuity improved, along with an increase in macular thickness. Vitamin<!--> <!-->A is essential for photoreceptor function, and its deficiency is associated with conditions such as xerophthalmia and keratopathy. OCT proved useful in monitoring treatment response. It is important to suspect hypovitaminosis<!--> <!-->A in patients with risk factors such as bariatric surgery or malabsorption, as its correction can enhance both retinal structure and visual function.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"100 12","pages":"Pages 798-801"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145623469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"El espectro de anomalías oftalmológicas en MELAS es más amplio de lo esperado","authors":"J. Finsterer","doi":"10.1016/j.oftal.2025.04.011","DOIUrl":"10.1016/j.oftal.2025.04.011","url":null,"abstract":"","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"100 12","pages":"Pages 808-809"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145623471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Ruiz del Rio, F. Garcia Ibor, E. Gracia Rovira, J.M. Vilaplana Mora, L. Sanz Gallen, A.M. Duch Samper
{"title":"Eficacia y seguridad del implante de acetónido de fluocinolona en edema macular y uveítis posterior no infecciosa: seguimiento de 5 años","authors":"N. Ruiz del Rio, F. Garcia Ibor, E. Gracia Rovira, J.M. Vilaplana Mora, L. Sanz Gallen, A.M. Duch Samper","doi":"10.1016/j.oftal.2025.07.003","DOIUrl":"10.1016/j.oftal.2025.07.003","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the safety and efficacy profile of the fluocinolone acetonide implant (FAI) in patients with non-infectious posterior segment uveitis over a 60-month follow-up period.</div></div><div><h3>Method</h3><div>We retrospective conducted a study with a mean follow-up of 47 months (minimum, 18; maximum, 60). The study included 11 eyes (9 patients), with a male-to-female ratio of 1:8. The etiology of uveitis was heterogeneous. Efficacy parameters included visual acuity (VA) and Central macular thickness (CMT), and the ones who needed adjuvant therapy or re-injection. Safety parameters focused on the development of cataracts and intraocular hypertension.</div></div><div><h3>Results</h3><div>Real-world outcomes were assessed. Both VA recovery and CMT reduction were achieved between 3 to 6 months after FAI implantation and remained stable at the follow-up. All patients but one were pseudophakic prior to implantation. The phakic patient developed early cataract formation, requiring surgery 9 months post-implantation. All cases had previously received intravitreal dexamethasone. Five eyes (45.4%) required topical hypotensive therapy, and none glaucoma surgery. No patient required periodic adjuvant therapy or additional FAI injections, even among those with the longest follow-up periods. Two cases (18.1%) exhibited mild inflammatory activity in the macular area at months 33 and 35 post-implantation. These episodes were successfully resolved with sub-Tenon triamcinolone injections, maintaining clinical stability thereafter.</div></div><div><h3>Conclusions</h3><div>The FAI, in our series of cases, turned out to be an effective and safe therapy for non-infectious uveitic macular edema, providing sustained and long-lasting effects, in some cases up to 60 months post-implantation. Sub-Tenon triamcinolone proves to be a valuable adjunctive therapy.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"100 12","pages":"Pages 752-758"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145623476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}