Archives of Physiology and Biochemistry最新文献_第8页

Polygala fallax Hemsl. ameliorated high glucose-induced podocyte injury by modulating mitochondrial mPTP opening through the SIRT1/PGC-1α pathway. 远志通过 SIRT1/PGC-1α 途径调节线粒体 mPTP 开放，从而改善高血糖诱导的荚膜细胞损伤。

IF 2.5 4区医学

Archives of Physiology and Biochemistry Pub Date : 2025-04-01 Epub Date: 2024-09-02 DOI: 10.1080/13813455.2024.2392298

Chao Shih-Wei, Bo Chen, Yanqing Mao, Qin Xu, Yige Chen

{"title":"Polygala fallax Hemsl. ameliorated high glucose-induced podocyte injury by modulating mitochondrial mPTP opening through the SIRT1/PGC-1α pathway.","authors":"Chao Shih-Wei, Bo Chen, Yanqing Mao, Qin Xu, Yige Chen","doi":"10.1080/13813455.2024.2392298","DOIUrl":"10.1080/13813455.2024.2392298","url":null,"abstract":"This study aimed to investigate the effects and molecular mechanism of PF on high glucose (HG)-induced podocyte injury. Results found that PF increased proliferation activity, decreased apoptosis, LDH, and caspase-3 levels, and increased nephrin and podocin expression in HG-induced cells. Similarly, PF improved HG-induced mitochondrial damage, decreased Ca2+ and ROS content, alleviated oxidative stress, inhibited mPTP opening, increased mitochondrial membrane potential, and decreased the expressions of Drp1, Bak, Bax, and Cytc in cytoplasm, increased the expressions of SIRT1, PGC-1α, HSP70, HK2, and Cytc in mitochondria of podocytes. The use of mPTP agonist/blocker and SIRT1 inhibitor confirmed that PF alleviates HG-induced podocyte injury by regulating mitochondrial mPTP opening through SIRT1/PGC-1α. In addition, PF affected HK2-VDAC1 protein binding to regulate mPTP opening via the SIRT1/PGC-1α pathway. In conclusion, PF-regulated HK2-VDAC1 protein binding affected mitochondrial mPTP opening and improved HG-induced podocyte injury through the SIRT1/PGC-1α pathway.","PeriodicalId":8331,"journal":{"name":"Archives of Physiology and Biochemistry","volume":" ","pages":"135-146"},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anti-inflammatory activity of the combination Ardisia humilis Vahl. and Curcuma xanthorrhiza Roxb. extract on an osteoarthritis rat model. 蒿草和莪术提取物复方制剂对骨关节炎大鼠模型的抗炎活性。

IF 2.5 4区医学

Archives of Physiology and Biochemistry Pub Date : 2025-04-01 Epub Date: 2024-09-26 DOI: 10.1080/13813455.2024.2406890

Sri Ningsih, Kurnia Agustini, Susi Kusumaningrum, Nisrina Firdausi, Agung Eru Wibowo, Julham Efendi, Ngatinem Ngatinem, Agus Himawan Subiantoro, Suparjo Suparjo, Catherine Catherine, Nasal Auni Rabbina, Anton Bahtiar, Rini Damayanti, KyuJong Lee

{"title":"Anti-inflammatory activity of the combination Ardisia humilis Vahl. and Curcuma xanthorrhiza Roxb. extract on an osteoarthritis rat model.","authors":"Sri Ningsih, Kurnia Agustini, Susi Kusumaningrum, Nisrina Firdausi, Agung Eru Wibowo, Julham Efendi, Ngatinem Ngatinem, Agus Himawan Subiantoro, Suparjo Suparjo, Catherine Catherine, Nasal Auni Rabbina, Anton Bahtiar, Rini Damayanti, KyuJong Lee","doi":"10.1080/13813455.2024.2406890","DOIUrl":"10.1080/13813455.2024.2406890","url":null,"abstract":"This study aimed to evaluate the anti-inflammatory activity of the combination of Ardisia humilis Vahl. and Curcuma xanthorrhiza Roxb. (AC) extract in monosodium iodoacetate (MIA)-induced osteoarthritis (OA) rat model. AC was administered orally to OA rats (240, 480, and 960 mg/kg bw) for three weeks. The control and model groups comprised OA rats treated with diclofenac sodium and carrier, respectively. AC-treated rats exhibited a significant reduction in oedema volume compared to those of the model group (p < 0.05). Notably, AC, at 960 mg/kg bw, significantly decreased inflammatory cytokines TNF-α and IL-1β, along with matrix metalloproteinase-9 (MMP-9) levels compared to those of the model group (p < 0.05). AC's attenuation of OA progression was also observed through haematoxylin and eosin (H&E) and Safranin O-fast green analysis. A phytochemical study showed AC contained phenolic, flavonoid, curcumin, demethoxycurcumin, and bisdemethoxycurcumin compounds. This study concludes that AC alleviated OA progression through anti-inflammatory effects and depressed MMP-9 levels.","PeriodicalId":8331,"journal":{"name":"Archives of Physiology and Biochemistry","volume":" ","pages":"199-209"},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142340138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Circular RNA NXN (circNXN) promotes diabetic retinopathy by regulating the miR-338-3p/FGFR1 axis. 环状 RNA NXN（circNXN）通过调节 miR-338-3p/FGFR1 轴促进糖尿病视网膜病变。

IF 2.5 4区医学

Archives of Physiology and Biochemistry Pub Date : 2025-04-01 Epub Date: 2025-02-23 DOI: 10.1080/13813455.2024.2404102

Yanbing Feng, Yongwei Zhu, Yixing Zhu, Yanting Lu, Yanyan He, Yibo Wu, Lijun Jiang, Wenqing Weng

引用次数: 0

Costunolide, an effective agent against oxidative damage, apoptosis and autophagy in the ovarian torsion/detorsion model. 在卵巢扭转/剥离模型中有效抑制氧化损伤、细胞凋亡和自噬的药物--Costunolide。

IF 2.5 4区医学

Archives of Physiology and Biochemistry Pub Date : 2025-04-01 Epub Date: 2024-09-23 DOI: 10.1080/13813455.2024.2407548

Pakistan Armin Akış, Ayhan Tanyeli, Fazile Nur Ekinci Akdemir, Mustafa Can Güler, Saime Özbek Şebin, Ersen Eraslan, Esra Laloğlu, Selim Çomaklı

{"title":"Costunolide, an effective agent against oxidative damage, apoptosis and autophagy in the ovarian torsion/detorsion model.","authors":"Pakistan Armin Akış, Ayhan Tanyeli, Fazile Nur Ekinci Akdemir, Mustafa Can Güler, Saime Özbek Şebin, Ersen Eraslan, Esra Laloğlu, Selim Çomaklı","doi":"10.1080/13813455.2024.2407548","DOIUrl":"10.1080/13813455.2024.2407548","url":null,"abstract":"Aim: This study assessed the efficacy of costunolide (COST) against oxidative tissue damage in the ovarian torsion/detorsion (TD) model.Methodology: Animals were randomly assigned to sham, ovarian TD, COST 5 mg/kg + ovarian TD, and COST 10 mg/kg + ovarian TD groups. COST's effectiveness was determined by assessing oxidative stress markers, interleukin levels, and histopathological examinations.Results: Oxidative stress markers were elevated in the ovarian TD group compared to the sham group. COST treatment represented a decline compared to the TD group. Besides, the antioxidant activity was significantly higher in the ovarian TD group than in the sham group. COST treatment improved the antioxidant parameters compared to the TD group. Inflammatory parameters, such as tumour necrosis factor- alpha (TNF-α) and interleukin 1-beta (IL-1β) were higher in the ovarian TD group than the sham group.Conclusion: COST treatment suppressed the proinflammatory cytokine expression compared to the TD group. Histopathological data supported these findings.","PeriodicalId":8331,"journal":{"name":"Archives of Physiology and Biochemistry","volume":" ","pages":"265-273"},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

High-intensity exercise alongside insulin alleviates muscle atrophy in type 1 diabetes mellitus concomitant with modulation of mitophagy-related proteins in skeletal muscle. 高强度运动和胰岛素可减轻 1 型糖尿病患者的肌肉萎缩，同时调节骨骼肌中的有丝分裂相关蛋白。

IF 2.5 4区医学

Archives of Physiology and Biochemistry Pub Date : 2025-04-01 Epub Date: 2024-10-09 DOI: 10.1080/13813455.2024.2410791

Manal Moustafa Mahmoud, Nahed Qutb Abdel Hameed, Basant Adel Al Dreny Abd Al Latef, Samaa Samir Kamar, Laila Ahmed Rashed, Sarah Ali Abdelhameed Gouda

{"title":"High-intensity exercise alongside insulin alleviates muscle atrophy in type 1 diabetes mellitus concomitant with modulation of mitophagy-related proteins in skeletal muscle.","authors":"Manal Moustafa Mahmoud, Nahed Qutb Abdel Hameed, Basant Adel Al Dreny Abd Al Latef, Samaa Samir Kamar, Laila Ahmed Rashed, Sarah Ali Abdelhameed Gouda","doi":"10.1080/13813455.2024.2410791","DOIUrl":"10.1080/13813455.2024.2410791","url":null,"abstract":"Background: Diabetes patients' quality of life can be severely impacted by diabetic muscle atrophy.Aim: This study aimed to explore the impact of high-intensity exercise (HIE) alongside insulin treatment on muscle atrophy in a rat model of type 1 diabetes mellitus (T1DM).Methodology: Fifty rats were allocated into five groups; Group 1, control sedentary (CS), T1DM was elicited in the rest of the groups by giving them Streptozotocin (STZ) (60 mg/kg), where group 2 (DS) remained sedentary, while groups 3,4,5 were treated with insulin after induction of diabetes. Group 4 (DI+MIE) and 5 (DI+ HIE) underwent moderate and high-intensity exercise, respectively.Results: HIE for 14 days combined with insulin treatment significantly restored muscle strength and mass with a significant modification in the mitophagy-related proteins and fibroblast growth factor 21 (FGF 21) compared to other treated groups.Conclusion: This study concluded that there is a therapeutic role for HIE with insulin against T1DM-induced muscle atrophy.","PeriodicalId":8331,"journal":{"name":"Archives of Physiology and Biochemistry","volume":" ","pages":"293-305"},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142387477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

HM-chromanone attenuates obesity and adipose tissue inflammation by downregulating SREBP-1c and NF-κb pathway in high-fat diet-fed mice. HM-色满酮通过下调 SREBP-1c 和 NF-κb 通路，减轻高脂饮食小鼠的肥胖和脂肪组织炎症。

IF 2.5 4区医学

Archives of Physiology and Biochemistry Pub Date : 2025-04-01 Epub Date: 2024-10-02 DOI: 10.1080/13813455.2024.2399554

Bo Ra Moon, Jae Eun Park, Ji Sook Han

{"title":"HM-chromanone attenuates obesity and adipose tissue inflammation by downregulating SREBP-1c and NF-κb pathway in high-fat diet-fed mice.","authors":"Bo Ra Moon, Jae Eun Park, Ji Sook Han","doi":"10.1080/13813455.2024.2399554","DOIUrl":"10.1080/13813455.2024.2399554","url":null,"abstract":"Background: Obese adipose tissue produces various pro-inflammatory cytokines that are major contributors to adipose tissue inflammation.Objective: The present study aimed to determine the effects of HM-chromanone (HMC) against obesity and adipose tissue inflammation in high-fat diet-fed mice.Materials and methods: Twenty-four C57BL/6J male mice were divided into three groups: ND (normal diet), HFD (high-fat diet), and HFD + HMC. The ND group was fed a normal diet, whereas the HFD and HFD + HMC groups were fed a high-fat diet. After 10 weeks of feeding, the animals were orally administered the treatments daily for 9 weeks. The ND and HFD group received distilled water as treatment. The HFD+HMC group was treated with HM-chromaone (50 mg/kg).Results: HM-chromanone administration decreased body weight, fat mass, and adipocyte diameter. HM-chromanone also improved plasma lipid profiles, decreased leptin levels, and increased adiponectin levels. The inhibiting effect of HM-chromanone on SREBP-1c, PPARγ, C/EBPα, and FAS decreased adipogenesis, thereby alleviating lipid accumulation. Furthermore, HM-chromanone administration exhibited a reduction in macrophage infiltration and the expression of pro-inflammatory cytokines. HM-chromanone suppressed the phosphorylation of IκBα and NF-κB, leading to the inhibition of iNOS and COX2 expressions, resulting in decreased inflammation in adipose tissue.Discussion and conclusion: These results highlight the anti-obesity and anti-inflammatory properties of HM-chromanone, achieved through the downregulation of the SREBP-1c and NF-κB pathway in high-fat diet-fed mice.","PeriodicalId":8331,"journal":{"name":"Archives of Physiology and Biochemistry","volume":" ","pages":"147-155"},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142364228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Combined swimming with melatonin protects against behavioural deficit in cerebral ischemia-reperfusion injury induced rats associated with modulation of Mst1- MAPK -ERK signalling pathway. 游泳与褪黑素联合使用可防止脑缺血再灌注损伤大鼠的行为缺陷，这与调节 Mst1- MAPK -ERK 信号通路有关。

IF 2.5 4区医学

Archives of Physiology and Biochemistry Pub Date : 2025-04-01 Epub Date: 2024-08-17 DOI: 10.1080/13813455.2024.2392186

Samah Mahmoud Abdelaal, Marwa Mohamed Abdel Rahman, Lamiaa Mohamed Mahmoud, Laila Ahmed Rashed, Tarek Ibrahim Abd El-Galil, Manal Moustafa Mahmoud

{"title":"Combined swimming with melatonin protects against behavioural deficit in cerebral ischemia-reperfusion injury induced rats associated with modulation of Mst1- MAPK -ERK signalling pathway.","authors":"Samah Mahmoud Abdelaal, Marwa Mohamed Abdel Rahman, Lamiaa Mohamed Mahmoud, Laila Ahmed Rashed, Tarek Ibrahim Abd El-Galil, Manal Moustafa Mahmoud","doi":"10.1080/13813455.2024.2392186","DOIUrl":"10.1080/13813455.2024.2392186","url":null,"abstract":"Background: The inconvenience of social and behavioural deficits after cerebral ischaemia reperfusion (I/R) injury is still not well documented.Aim: We aimed to study the protective effect of preconditioning swimming exercise combined with melatonin against cerebral I/R induced injury.Methodology: Sixty rats were allocated into 6 groups; groups I and II served as control. Groups 3,4,5,6 subjected to bilateral carotid ligation for 30 minutes (min.) followed by reperfusion. Group 3 left untreated while groups 4 and 6; underwent swimming exercise 30 min/day, five days a week for three weeks before the surgery. Groups 5 and 6 treated with melatonin 30 minutes before the operation, then, all rats in groups 4, 5,6 were subjected to I/R. After that, groups 5 and 6 treated with 2nd dose of melatonin 30 minutes after reperfusion.Results: Combined strategy exhibited the most neuroprotective effect through prevention of cerebral I/R induced inflammation, oxidative stress and apoptosis with subsequent improvement in socio behaviour deficits and enhanced Glial cell proliferative capacity.Conclusion: The protective contribution of combined strategy is associated with modulation in Macrophage-stimulating 1/mitogen-activated protein kinase/extracellular signal-regulated kinase (MST1/MAPK/ERK) pathway which may explain, at least in part, its protective potential.","PeriodicalId":8331,"journal":{"name":"Archives of Physiology and Biochemistry","volume":" ","pages":"119-134"},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141995156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Glucose metabolism in the perfused liver did not improve with resistance training in male Swiss mice under caloric restriction. 雄性瑞士小鼠在热量限制条件下进行阻力训练后，灌注肝脏中的葡萄糖代谢并没有得到改善。

IF 2.5 4区医学

Archives of Physiology and Biochemistry Pub Date : 2025-04-01 Epub Date: 2024-10-11 DOI: 10.1080/13813455.2024.2413626

Julio Ernesto Perego Junior, Kauane Tomazi Silva, Ana Luiza Balani Rando, Mateus Sousa Lima, Rosângela Fernandes Garcia, Maria Montserrat Diaz Pedrosa

{"title":"Glucose metabolism in the perfused liver did not improve with resistance training in male Swiss mice under caloric restriction.","authors":"Julio Ernesto Perego Junior, Kauane Tomazi Silva, Ana Luiza Balani Rando, Mateus Sousa Lima, Rosângela Fernandes Garcia, Maria Montserrat Diaz Pedrosa","doi":"10.1080/13813455.2024.2413626","DOIUrl":"10.1080/13813455.2024.2413626","url":null,"abstract":"Context: Energy homeostasis is a primary factor for the survival of mammals. Many tissues and organs, among which is the liver, keep this homeostasis in varied circumstances, including caloric restriction (CR) and physical activity.Objective: This study investigated glucose metabolism using the following groups of eight-week-old male Swiss mice: CS, sedentary and fed freely; RS, sedentary and RT, trained, both under 30% CR (n = 20-23 per group).Results: Organs and fat depots of groups RS and RT were similar to CS, although body weight was lower. CR did not impair training performance nor affected systemic or hepatic glucose metabolism. Training combined with CR (group RT) improved in vivo glucose tolerance and did not affect liver gluconeogenesis.Conclusions: The mice tolerated the prolonged moderate CR without impairment of their well-being, glucose homeostasis, and resistance training performance. But the higher liver gluconeogenic efficiency previously demonstrated using this training protocol in mice was not evidenced under CR.","PeriodicalId":8331,"journal":{"name":"Archives of Physiology and Biochemistry","volume":" ","pages":"306-315"},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142399141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Regulatory effect and mechanism of CircSEC24A in IL-1β-induced osteoarthritis. CircSEC24A在IL-1β诱导的骨关节炎中的调节作用和机制

IF 2.5 4区医学

Archives of Physiology and Biochemistry Pub Date : 2025-04-01 Epub Date: 2024-09-27 DOI: 10.1080/13813455.2024.2404975

Yuanrui Wang, Xiaochao Chen, Yongfeng Chen, Qiang Sun, Huayi Wang

引用次数: 0

Network pharmacology and in silico study of quercetin and structurally similar flavonoids as osteogenesis inducers that interact with oestrogen receptors. 槲皮素和结构相似的类黄酮作为与雌激素受体相互作用的成骨诱导剂的网络药理学和计算机研究。

IF 2.5 4区医学

Archives of Physiology and Biochemistry Pub Date : 2025-03-31 DOI: 10.1080/13813455.2025.2483910

Mohammad-Sadegh Lotfi, Hamidreza Jamali, Fatemeh B Rassouli

{"title":"Network pharmacology and in silico study of quercetin and structurally similar flavonoids as osteogenesis inducers that interact with oestrogen receptors.","authors":"Mohammad-Sadegh Lotfi, Hamidreza Jamali, Fatemeh B Rassouli","doi":"10.1080/13813455.2025.2483910","DOIUrl":"https://doi.org/10.1080/13813455.2025.2483910","url":null,"abstract":"Background: Osteoporosis poses a global health challenge, particularly with an ageing population. Quercetin, isorhamnetin, avicularin, isoquercetin, quercitrin, and taxifolin are natural flavonoids with similar structure that induce ontogenesis.Methods: In the present study, proteins in oestrogen signalling and bone morphogenesis were analysed, and hub genes were identified with Cytoscape, followed by pathway analysis. Then, molecular targets of flavonoids and osteoporosis-related targets were identified, and overlaps were detected. Molecular docking and dynamics simulations assessed flavonoid interactions with ERs.Results: The study identified 14 gene products linked to osteoporosis, including ESR1 and ESR2. Enrichment analyses confirmed ESR involvement in various biological processes. SwissTargetPrediction highlighted quercetin and isorhamnetin as favourable targets for ESR1 and ESR2. Molecular docking and dynamics revealed favourable and stable binding of flavonoids to ERα and ERβ.Conclusion: These interactions suggest therapeutic potential of natural flavonoids for osteoporosis treatment by targeting ERs, laying a foundation for future research in preclinical and clinical settings.","PeriodicalId":8331,"journal":{"name":"Archives of Physiology and Biochemistry","volume":" ","pages":"1-12"},"PeriodicalIF":2.5,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0