Archives of Physiology and Biochemistry最新文献_第8页

Cross-sectional study on the connection between collateral status and cognitive impairment after stroke based on neural regulation and protein metabolism. 基于神经调节和蛋白质代谢的脑卒中后侧支状态与认知功能障碍关系的横断面研究。

IF 2.7 4区医学

Archives of Physiology and Biochemistry Pub Date : 2026-04-01 Epub Date: 2025-09-05 DOI: 10.1080/13813455.2025.2556009

Shufen Zhang, Jiwei Cheng, Chuansen Liu, Yunyun Zhang

{"title":"Cross-sectional study on the connection between collateral status and cognitive impairment after stroke based on neural regulation and protein metabolism.","authors":"Shufen Zhang, Jiwei Cheng, Chuansen Liu, Yunyun Zhang","doi":"10.1080/13813455.2025.2556009","DOIUrl":"10.1080/13813455.2025.2556009","url":null,"abstract":"Background: Post-stroke cognitive impairment (PSCI), a common complication following stroke, significantly impacts patients' quality of life and prognosis. Research indicates that neuroregulation and protein metabolic disorders play crucial roles in the development of PSCI.Purpose: This study aimed to evaluate the reliability of the Regional Meningoarterial Score (rLMC) in determining collateral circulation status in acute ischaemic stroke patients.Method: Participants were selected based on specific criteria including MRI-detected recent cerebral infarction, absence of prior large-scale subcortical infarction or haemorrhage, and no history of Alzheimer's disease or cognitive impairment.Results: The results showed that cognitive impairment group (CI group) exhibited significantly lower serum acetylcholine levels compared to normal control group (CN group), while β-amyloid protein levels were markedly higher. CI group also demonstrated reduced expression of neuroregulatory factors.Conclusion: These findings demonstrate that neuroregulatory factors and protein metabolites can serve as potential biomarkers for early diagnosis and intervention, effectively predicting post-stroke cognitive impairment.","PeriodicalId":8331,"journal":{"name":"Archives of Physiology and Biochemistry","volume":" ","pages":"177-185"},"PeriodicalIF":2.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144999533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Qualitative study on cancer diagnosis and primary caregiver coping experience based on infra-red thermography: Impact of protein metabolism and immune function. 基于红外热成像的癌症诊断和主要照顾者应对经验的定性研究：蛋白质代谢和免疫功能的影响。

IF 2.7 4区医学

Archives of Physiology and Biochemistry Pub Date : 2026-04-01 Epub Date: 2025-09-29 DOI: 10.1080/13813455.2025.2567347

Liu Jia, Zeng Lingpiao, Hu Jiayin, Huang Qiyun, Yang Yirong

{"title":"Qualitative study on cancer diagnosis and primary caregiver coping experience based on infra-red thermography: Impact of protein metabolism and immune function.","authors":"Liu Jia, Zeng Lingpiao, Hu Jiayin, Huang Qiyun, Yang Yirong","doi":"10.1080/13813455.2025.2567347","DOIUrl":"10.1080/13813455.2025.2567347","url":null,"abstract":"Traditional cancer diagnosis methods include imaging examinations, biopsy, etc., but these methods are often invasive, time-consuming, and costly. This study aims to explore the application effect of infra-red thermography technology in cancer diagnosis and analyse the coping experience of primary caregivers during patient diagnosis and treatment. The data collection methods include semi-structured interviews, observations, and questionnaire surveys. The research results show that infra-red thermography technology has high sensitivity and specificity in cancer diagnosis, which can assist doctors in detecting early signs of tumours. Therefore, cancer diagnosis technology based on infra-red thermography has shown great potential in early detection and is expected to become a beneficial supplement to traditional diagnostic methods. At the same time, caregivers' coping experiences during cancer diagnosis and treatment are complex and diverse, requiring the healthcare system to provide more support and resources to help them better adapt and cope.","PeriodicalId":8331,"journal":{"name":"Archives of Physiology and Biochemistry","volume":" ","pages":"194-205"},"PeriodicalIF":2.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145184606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lipid peroxidation as a driver of oxidative and neuroinflammatory damage in ocular disease: review and perspectives. 脂质过氧化作为眼部疾病中氧化和神经炎症损伤的驱动因素：综述和观点。

IF 2.7 4区医学

Archives of Physiology and Biochemistry Pub Date : 2026-03-27 DOI: 10.1080/13813455.2026.2628183

Fei Chen, Yunjie Shi

引用次数: 0

Impaired lipid homeostasis and mitochondrial dysfunction in critical limb ischaemia caused by arteriosclerosis obliterans. 动脉硬化闭塞性肢体缺血引起的脂质稳态受损和线粒体功能障碍。

IF 2.7 4区医学

Archives of Physiology and Biochemistry Pub Date : 2026-03-13 DOI: 10.1080/13813455.2025.2592019

Shengyuan Mao, Hanjun Wang

引用次数: 0

Diagnosis of medication and clinical services for chronic metabolic diseases: a survey of pharmaceutical services in Shaoxing City based on the medical alliance model. 慢性代谢性疾病用药诊断与临床服务：基于医疗联盟模式的绍兴市药学服务调查

IF 2.7 4区医学

Archives of Physiology and Biochemistry Pub Date : 2026-03-11 DOI: 10.1080/13813455.2026.2632825

Qin Ye, Zheming Wang, Qizhi Yan, Zhihua Tang

{"title":"Diagnosis of medication and clinical services for chronic metabolic diseases: a survey of pharmaceutical services in Shaoxing City based on the medical alliance model.","authors":"Qin Ye, Zheming Wang, Qizhi Yan, Zhihua Tang","doi":"10.1080/13813455.2026.2632825","DOIUrl":"https://doi.org/10.1080/13813455.2026.2632825","url":null,"abstract":"Background: Hierarchical medical treatment is the core system of China's medical reform. The medical alliance model, as an important carrier, has been promoted nationwide. Purpose: This study aims to comprehensively assess the current status of pharmaceutical services in the medical alliance of Shaoxing City, with a focus on the application of metabolic abnormality tests, providing a basis for improving service homogeneity. Methods: The study adopted the cross-sectional survey method. Questionnaires were distributed to the heads of the pharmacy departments of 4 general hospitals of the medical alliance and 23 branch hospitals in Shaoxing from April to May 2021. Discussion: Measures such as optimising the allocation of testing resources, improving unified standards and mutual recognition mechanisms, and strengthening the collaboration between testing and pharmaceutical services should be taken to enhance the homogenisation level of metabolic abnormality tests, thereby comprehensively improving the pharmaceutical service capabilities of the medical alliance and promoting implementation of hierarchical medical treatment.","PeriodicalId":8331,"journal":{"name":"Archives of Physiology and Biochemistry","volume":" ","pages":"1-10"},"PeriodicalIF":2.7,"publicationDate":"2026-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147430682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lipid-mediated brain-gut axis alterations in functional diarrhea and their role in oxidative stress and neurodegeneration. 功能性腹泻中脂质介导的脑肠轴改变及其在氧化应激和神经变性中的作用。

IF 2.7 4区医学

Archives of Physiology and Biochemistry Pub Date : 2026-02-25 DOI: 10.1080/13813455.2026.2628181

Zhixin Wang, Lifang Shi, Xuemei Wang, Lingyan Zhao, Huijuan Liang, Shiqi Wang

{"title":"Lipid-mediated brain-gut axis alterations in functional diarrhea and their role in oxidative stress and neurodegeneration.","authors":"Zhixin Wang, Lifang Shi, Xuemei Wang, Lingyan Zhao, Huijuan Liang, Shiqi Wang","doi":"10.1080/13813455.2026.2628181","DOIUrl":"https://doi.org/10.1080/13813455.2026.2628181","url":null,"abstract":"Lipid mediators control intestinal motility, epithelial signalling, and neuronal function by integrating metabolic, hormonal, and neurological interactions throughout the brain-gut axis. Recurrent loose stools without structural abnormalities are the hallmark of Functional Diarrhoea (FD), a condition marked by high oxidative stress and disruptions in this axis. The main aim of this work is to further understand the role of lipid profiles in oxidative stress and neurological abnormalities in FD using the proposed Lipid-Mediated Brain-Gut Axis (LIMBRA) model. The LIMBRA system analyzes lipid abnormalities using targeted blood and faecal lipidomics with oxidative stress and cognitive assessment. FD showed mild cognitive impairment, high oxidative stress, increased lipid peroxidation, and reduced omega-3 anti-inflammatory mediators. These findings support a lipid-based mechanism linking gastrointestinal dysregulation to brain oxidative stress and neurodegeneration, providing a foundation for future studies on lipid biomarkers and therapies for FD and related cognitive disorders.","PeriodicalId":8331,"journal":{"name":"Archives of Physiology and Biochemistry","volume":" ","pages":"1-12"},"PeriodicalIF":2.7,"publicationDate":"2026-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147281873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical analysis of left upper limb ulnar nerve sheath tumour combined with cubital tunnel syndrome: neuroinflammatory intervention. 左上肢尺神经鞘肿瘤合并肘管综合征的临床分析：神经炎症干预。

IF 2.7 4区医学

Archives of Physiology and Biochemistry Pub Date : 2026-02-10 DOI: 10.1080/13813455.2026.2628190

Zhekai Shi, Jiale Chen, Junxuan Wang, Rui Wang, Yongping Li

{"title":"Clinical analysis of left upper limb ulnar nerve sheath tumour combined with cubital tunnel syndrome: neuroinflammatory intervention.","authors":"Zhekai Shi, Jiale Chen, Junxuan Wang, Rui Wang, Yongping Li","doi":"10.1080/13813455.2026.2628190","DOIUrl":"https://doi.org/10.1080/13813455.2026.2628190","url":null,"abstract":"Schwannoma of the ulnar nerve is often closely related to cubital tunnel syndrome. Neuroinflammation plays a significant role in the pathogenesis of ulnar schwannoma and cubital tunnel syndrome. This study aims to explore the application value of thermal radiation imaging technology in the diagnosis of ulnar schwannoma combined. After neuroinflammatory intervention, the patient's pain and numbness symptoms were significantly alleviated. Thermal radiation images show that the state of neuroinflammation is closely related to the improvement of neurological function. Thermal radiation imaging technology holds significant clinical importance in the diagnosis and treatment evaluation of ulnar schwannoma combined with cubital tunnel syndrome. It can provide real-time monitoring data of neuroinflammation and assist doctors in formulating more effective treatment plans. Neuroinflammatory intervention has shown good effects in alleviating patients' symptoms and promoting the recovery of neurological function, providing new ideas and methods for the treatment of ulnar schwannoma combined with cubital tunnel syndrome.","PeriodicalId":8331,"journal":{"name":"Archives of Physiology and Biochemistry","volume":" ","pages":"1-12"},"PeriodicalIF":2.7,"publicationDate":"2026-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146148890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Protein tyrosine phosphatase 1B protein macromolecule combined with aerobic exercise intervention on lipid metabolism in type II diabetes patients. 蛋白酪氨酸磷酸酶1B蛋白大分子联合有氧运动干预2型糖尿病患者脂质代谢

IF 2.7 4区医学

Archives of Physiology and Biochemistry Pub Date : 2026-02-09 DOI: 10.1080/13813455.2026.2628187

Wang Xujiu, Zhengkun Li

{"title":"Protein tyrosine phosphatase 1B protein macromolecule combined with aerobic exercise intervention on lipid metabolism in type II diabetes patients.","authors":"Wang Xujiu, Zhengkun Li","doi":"10.1080/13813455.2026.2628187","DOIUrl":"https://doi.org/10.1080/13813455.2026.2628187","url":null,"abstract":"Context: With the increasing incidence rate of type II diabetes, it is particularly important to study its potential molecular mechanism and intervention means. Protein tyrosine phosphatase 1B (PTP1B) plays a crucial role in insulin signalling and lipid metabolism.Objective: The purpose of this study was to explore the effect of PTP1B protein macromolecule on lipid metabolism in type II diabetes patients under the intervention of aerobic exercise.Materials and methods: The subjects were type II diabetes patients who had undergone aerobic exercise intervention. There were no significant abnormalities in liver and kidney function, indicating the safety of the intervention method. Therefore, PTP1B plays an important role in the regulation of lipid metabolism in type II diabetes.Conclusion: Aerobic exercise, as an effective intervention, can significantly improve the lipid metabolism in type II diabetes patients by affecting the function of PTP1B, thus providing new ideas and methods for clinical treatment.","PeriodicalId":8331,"journal":{"name":"Archives of Physiology and Biochemistry","volume":" ","pages":"1-9"},"PeriodicalIF":2.7,"publicationDate":"2026-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146140937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of radiation therapy combined with immunotherapy based on bio optical imaging on serum tumour markers and immune function in lung cancer patients: metabolic abnormality test. 基于生物光学成像的放射联合免疫治疗对肺癌患者血清肿瘤标志物和免疫功能的影响：代谢异常试验。

IF 2.7 4区医学

Archives of Physiology and Biochemistry Pub Date : 2026-02-06 DOI: 10.1080/13813455.2026.2628186

Yu Genhua, Huili Liu, Yingying Peng, Ning Wang, Xufeng Gong

{"title":"The effect of radiation therapy combined with immunotherapy based on bio optical imaging on serum tumour markers and immune function in lung cancer patients: metabolic abnormality test.","authors":"Yu Genhua, Huili Liu, Yingying Peng, Ning Wang, Xufeng Gong","doi":"10.1080/13813455.2026.2628186","DOIUrl":"https://doi.org/10.1080/13813455.2026.2628186","url":null,"abstract":"Lung cancer is one of the malignant tumours with the highest incidence rate and mortality in the world, among which non small cell lung cancer (NSCLC) accounts for a relatively high proportion. Patients with locally advanced non-small cell lung cancer who cannot be surgically resected usually receive radiotherapy, but the effectiveness of a single treatment is limited. The results indicate that radiotherapy combined with immunotherapy has significant clinical efficacy in patients with locally advanced non-small cell lung cancer who cannot undergo surgical resection. Metabolic abnormality testing has important value in monitoring treatment efficacy and patient metabolic status, and can provide reference for optimising clinical treatment plans. Future research should further explore the application value of metabolic abnormality testing in the treatment of lung cancer, and combine it with other detection methods to provide more comprehensive and reliable treatment basis for clinical practice.","PeriodicalId":8331,"journal":{"name":"Archives of Physiology and Biochemistry","volume":" ","pages":"1-9"},"PeriodicalIF":2.7,"publicationDate":"2026-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146123737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characteristics of 3D pCASL parameters in patients with moyamoya disease and their predictive value for cognitive function after revascularization surgery. 烟雾病患者三维pCASL参数特征及其对血运重建术后认知功能的预测价值

IF 2.7 4区医学

Archives of Physiology and Biochemistry Pub Date : 2026-02-06 DOI: 10.1080/13813455.2026.2628189

Shiyuan Zhang, Zhizhao Ma, Lijie Liu, Yeju He, Xiaotong Li, Zuojun Geng

{"title":"Characteristics of 3D pCASL parameters in patients with moyamoya disease and their predictive value for cognitive function after revascularization surgery.","authors":"Shiyuan Zhang, Zhizhao Ma, Lijie Liu, Yeju He, Xiaotong Li, Zuojun Geng","doi":"10.1080/13813455.2026.2628189","DOIUrl":"https://doi.org/10.1080/13813455.2026.2628189","url":null,"abstract":"Background: Moyamoya disease is a chronic progressive cerebrovascular disease, characterised by stenosis or occlusion of the ends and branches of bilateral internal carotid arteries, accompanied by the formation of abnormal vascular networks at the base of the skull.Purpose: Through non-invasive detection techniques such as magnetic resonance spectroscopy (MRS), diffusion tensor imaging (DTI). It provides important basis for clinical treatment.Method: This study aims to explore the characteristics of three-dimensional pseudo-continuous arterial spin labelling (3D-pCASL) parameters in patients with moyamoya disease and their predictive value for the improvement of cognitive function after revascularization, and to investigate the potential application value of 3D-pCASL parameters in evaluating neuronal injury and predicting the improvement of postoperative cognitive function.Conclusion: This study further confirmed the application value of 3D-pCASL parameters in the examination of neuronal injury and the prediction of postoperative cognitive function improvement, providing an objective imaging basis for the early clinical identification of patients.","PeriodicalId":8331,"journal":{"name":"Archives of Physiology and Biochemistry","volume":" ","pages":"1-13"},"PeriodicalIF":2.7,"publicationDate":"2026-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146123698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0