Angiology最新文献_第6页

Letter: Remnant Cholesterol as a Predictor of No-Reflow Phenomenon in Patients With ST-Segment Elevation Myocardial Infarction. 信：残余胆固醇作为st段抬高型心肌梗死患者无血流现象的预测因子。

IF 2.7 3区医学

Angiology Pub Date : 2026-10-01 Epub Date: 2026-04-03 DOI: 10.1177/00033197261435380

Omer Dogan, Hasan Ali Barman, Abdullah Omer Ebeoglu, Sevval Ilke Ebeoglu, Ali Nayir, Melike Kaya, Adem Atici, Khayel Mirzayev, Okay Abaci, Murat Kazim Ersanli, Sait Mesut Dogan, Veysel Oktay

引用次数: 0

The Impact of Epilepsy, Antiepileptic Drugs, and Adjuvant Treatments on Subclinical Atherosclerosis: A Systematic Review and Meta-Analysis. 癫痫、抗癫痫药物和辅助治疗对亚临床动脉粥样硬化的影响：系统回顾和荟萃分析。

IF 2.7 3区医学

Angiology Pub Date : 2026-10-01 Epub Date: 2025-11-06 DOI: 10.1177/00033197251384353

Yupeng Wu, Liu Yang, Xiaojiao Zhang, Zaihan Zhu, Peizhuo Zang, Dandan Sun

{"title":"The Impact of Epilepsy, Antiepileptic Drugs, and Adjuvant Treatments on Subclinical Atherosclerosis: A Systematic Review and Meta-Analysis.","authors":"Yupeng Wu, Liu Yang, Xiaojiao Zhang, Zaihan Zhu, Peizhuo Zang, Dandan Sun","doi":"10.1177/00033197251384353","DOIUrl":"10.1177/00033197251384353","url":null,"abstract":"Epilepsy, antiepileptic drugs (AEDs), and adjuvant treatments may correlate with the development of subclinical atherosclerosis. We performed a systematic review and meta-analysis to evaluate the effects of epilepsy, AEDs, and adjuvant treatments on the structural and functional markers of subclinical atherosclerosis represented by carotid intima-media thickness (cIMT), epicardial adipose tissue thickness (EATT), and flow-mediated vasodilation (FMD). Weighted mean differences (WMD) and corresponding 95% confidence intervals (CIs) were analyzed. Thirty-one studies were included with 9 different outcomes. Compared with controls, the epileptic patients demonstrated significantly thicker cIMT (WMD [95% CI] = 0.063 [0.045-0.080], P < .001) and EATT (WMD [95% CI] = 1.985 [1.630-2.341], P < .001). There was no significant difference in FMD (P > .050). Moreover, cIMT was still thicker in the epileptic patients on old AEDs compared with those on new AEDs (WMD [95% CI] = 0.038 [0.000-0.076], P = .050), on multi-AEDs compared with on mono-AEDs (WMD [95% CI] = 0.025 [0.021-0.029], P < .001), and on enzyme-inducing AEDs compared with on non-enzyme-inducing AEDs (WMD [95% CI] = 0.027 [0.006-0.047], P = .011). No significant differences in cIMT were detected in any comparison of adjuvant treatments (ketogenic diet, Atkins diet, and folic acid supplements; all P > .050). Epilepsy and AEDs, especially old AEDs, multi-AEDs, and enzyme-inducing AEDs, could exacerbate the development of subclinical atherosclerosis. Early prevention as well as timely intervention for subclinical atherosclerosis should be considered for these patients.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"1098-1109"},"PeriodicalIF":2.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145450507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Associations Between Ratio of Red Blood Cell Distribution Width to Albumin With Cardiovascular Mortality and Specific Cardiovascular Disease. 红细胞分布宽度与白蛋白比值与心血管死亡率和特定心血管疾病的关系

IF 2.7 3区医学

Angiology Pub Date : 2026-10-01 Epub Date: 2025-11-20 DOI: 10.1177/00033197251390167

Yan Zhang, Zhuhua Yao

{"title":"Associations Between Ratio of Red Blood Cell Distribution Width to Albumin With Cardiovascular Mortality and Specific Cardiovascular Disease.","authors":"Yan Zhang, Zhuhua Yao","doi":"10.1177/00033197251390167","DOIUrl":"10.1177/00033197251390167","url":null,"abstract":"The ratio of red cell distribution width (RDW) to albumin (RAR) has been shown to correlate with poor prognosis in patients with various diseases. However, the relationship between RAR and cardiovascular disease (CVD) remains inadequately elucidated. We conducted this study using data from 12 755 participants in the National Health and Nutrition Examination Survey (NHANES) 2007 to 2018. Multivariable regression analysis and subgroup analysis were conducted to analyze the potential relationship. In this study, RAR was significantly and positively associated with CVD mortality (hazard ratio [HR] = 1.99, 95% CI = 1.81-2.19, P < .001), total CVD (odds ratios [OR] = 1.42, 95% CI = 1.31-1.54, P < .001), congestive heart failure (CHF; OR = 1.70, 95% CI = 1.52-1.90, P < .001), coronary heart disease (CHD; OR = 1.18, 95% CI = 1.05-1.33 P = .006), and myocardial infarction (MI; OR = 1.32, 95% CI = 1.18-1.47, P < .001). Subgroup analyses confirmed the robustness of the findings. Our findings demonstrate significant and independent associations of RAR levels with CVD mortality and specific CVD. As a straightforward, cost-effective, and readily accessible metric, RAR has the potential to offer novel insights into CVD risk assessment.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"1116-1126"},"PeriodicalIF":2.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145556170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Remnant Cholesterol as a Predictor of No-Reflow Phenomenon in Patients With ST-Segment Elevation Myocardial Infarction. 残余胆固醇作为st段抬高型心肌梗死患者无血流现象的预测因子

IF 2.7 3区医学

Angiology Pub Date : 2026-10-01 Epub Date: 2025-12-27 DOI: 10.1177/00033197251395822

Omer Dogan, Hasan Ali Barman, Abdullah Omer Ebeoglu, Sevval Ilke Guneysu, Ali Nayir, Melike Kaya, Adem Atıcı, Khayal Mirzayev, Okay Abaci, Murat Kazim Ersanli, Sait Mesut Dogan, Veysel Oktay

{"title":"Remnant Cholesterol as a Predictor of No-Reflow Phenomenon in Patients With ST-Segment Elevation Myocardial Infarction.","authors":"Omer Dogan, Hasan Ali Barman, Abdullah Omer Ebeoglu, Sevval Ilke Guneysu, Ali Nayir, Melike Kaya, Adem Atıcı, Khayal Mirzayev, Okay Abaci, Murat Kazim Ersanli, Sait Mesut Dogan, Veysel Oktay","doi":"10.1177/00033197251395822","DOIUrl":"10.1177/00033197251395822","url":null,"abstract":"Remnant cholesterol (RC) has been implicated in the progression of atherosclerotic cardiovascular disease. However, the impact of RC levels on the occurrence of no-reflow in patients with ST-segment elevation myocardial infarction (STEMI) who underwent primary percutaneous coronary intervention (pPCI) remains poorly understood. Patients were classified into 2 groups: those (n = 90) who developed no-reflow (+) and those (n = 350) who did not develop no-reflow (-). RC was calculated as total cholesterol minus low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C). RC (Odds Ratio [OR] = 1.28, P < .001), diabetes mellitus (OR = 2.72, P = .002), stent length (OR = 1.07, P = .020), door-to-balloon time (OR = 1.04, P = .047), symptom-to-admission time (OR = 2.07, P = .002) and presence of thrombus (OR = 2.34, P < 0.001) were independent predictors of no-reflow. RC was shown to predict no-reflow development (Area under the curve [AUC] = 0.923, P < .001). The present study revealed a significant association between RC levels and the occurrence of the no-reflow phenomenon following pPCI in patients with STEMI. Assessment of RC levels may assist in identifying high-risk groups in STEMI patients and may prove to be an important factor to manage for cardiovascular health.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"1191-1197"},"PeriodicalIF":2.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145843483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comment on "Inflammatory Indices as a Triage Tool for Contrast-Enhanced Ultrasound in Carotid Plaques". “炎症指标作为超声造影检查颈动脉斑块的分诊工具”评论。

IF 2.7 3区医学

Angiology Pub Date : 2026-09-29 DOI: 10.1177/00033197261492887

Guanyan Cai, Liping Zheng, Jinfeng Su

引用次数: 0

Endovascular Treatment for Symptomatic SISMAD: A Methodological Critique. 血管内治疗症状性SISMAD：方法学批判。

IF 2.7 3区医学

Angiology Pub Date : 2026-09-29 DOI: 10.1177/00033197261495232

Menghui Mao, Derong Bao

引用次数: 0

Balance, Muscle Strength, and Functional Decline in Peripheral Arterial Disease: A Systematic Review and Meta-Analysis. 外周动脉疾病的平衡、肌肉力量和功能下降：系统回顾和荟萃分析。

IF 2.7 3区医学

Angiology Pub Date : 2026-09-28 DOI: 10.1177/00033197261492894

Alexia Gavriilidou, Argirios Giannopoulos, Vasiliki Manaki, Panagiotis Tsaklis, Maria Nefeli Ktenidou, Kosmas Christoulas, Ioannis Lazaridis

{"title":"Balance, Muscle Strength, and Functional Decline in Peripheral Arterial Disease: A Systematic Review and Meta-Analysis.","authors":"Alexia Gavriilidou, Argirios Giannopoulos, Vasiliki Manaki, Panagiotis Tsaklis, Maria Nefeli Ktenidou, Kosmas Christoulas, Ioannis Lazaridis","doi":"10.1177/00033197261492894","DOIUrl":"https://doi.org/10.1177/00033197261492894","url":null,"abstract":"Peripheral arterial disease (PAD) is associated with impaired physical performance beyond walking limitation, including reduced muscle strength, impaired balance, and increased risk of falls. We performed a systematic review and exploratory meta-analysis following PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses) 2020 guidelines to evaluate the association between PAD severity and functional outcomes. Twelve studies involving 2083 patients with PAD were included. Study-level associations between clinical characteristics (ankle-brachial index [ABI], claudication, smoking, and statin use) and functional outcomes (balance performance, Timed Up-and-Go Test, Short Physical Performance Battery, 6-minute walk distance, and handgrip strength) were examined using Spearman's correlation and random-effects meta-regression. Claudication was associated with poorer balance, greater fear of falling, and slower Timed Up-and-Go performance, while smoking correlated with lower handgrip strength and increased fear of falling. Higher ABI values were associated with better walking performance, and meta-regression demonstrated significant associations between lower ABI and slower gait speed and poorer lower-extremity function. These findings suggest that greater PAD severity is associated with impaired balance, muscle weakness, and reduced functional mobility. Early functional assessment and targeted rehabilitation strategies, including balance and strength training, may help reduce frailty and fall risk in patients with PAD.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197261492894"},"PeriodicalIF":2.7,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149073387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Narrative Review of the Prognostic Value of Soluble Urokinase-Type Plasminogen Activator Receptor (suPAR) in Cardiovascular Disease. 可溶性尿激酶型纤溶酶原激活物受体（suPAR）在心血管疾病中的预后价值综述

IF 2.7 3区医学

Angiology Pub Date : 2026-09-26 DOI: 10.1177/00033197261489648

Georgios V Tsamourlidis, Dimitrios A Chatzelas, Apostolos G Pitoulias, Theodosia N Zampaka, Maria D Tachtsi, Anastasios G Potouridis, Georgios A Pitoulias

{"title":"A Narrative Review of the Prognostic Value of Soluble Urokinase-Type Plasminogen Activator Receptor (suPAR) in Cardiovascular Disease.","authors":"Georgios V Tsamourlidis, Dimitrios A Chatzelas, Apostolos G Pitoulias, Theodosia N Zampaka, Maria D Tachtsi, Anastasios G Potouridis, Georgios A Pitoulias","doi":"10.1177/00033197261489648","DOIUrl":"https://doi.org/10.1177/00033197261489648","url":null,"abstract":"The soluble urokinase-type plasminogen activator receptor (suPAR) is a promising biomarker associated with various clinical entities. This review considers the association between suPAR and cardiovascular (CV) disease (CVD). We conducted a comprehensive electronic search of the literature on suPAR and CVD. PubMed/MEDLINE, Scopus, Web of Science, and the Cochrane Library were searched from inception to December 31, 2025. Raised suPAR levels are independently associated with atherosclerosis, coronary artery disease, myocardial infarction, peripheral arterial disease (PAD) and related events and overall CV mortality. suPAR reflects inflammatory pathways distinct from those captured by C-reactive protein and is less affected by anthropometric parameters. suPAR levels correlate with endothelial dysfunction, the severity and extent of PAD and coronary artery calcium score, plaque inflammation and neointima hyperplasia. The variant rs4760 of the Plasminogen Activator, Urokinase Receptor gene that encodes suPAR may promote atherosclerosis. Lifestyle interventions and pharmacologic therapies may reduce suPAR levels. suPAR represents a robust biomarker with the potential to enhance personalized management of CVD. Despite strong evidence supporting its prognostic value, the clinical integration of suPAR remains limited. Future research should investigate its utility in risk stratification, monitoring of therapeutic response, and perioperative CV risk assessment.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197261489648"},"PeriodicalIF":2.7,"publicationDate":"2026-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149057455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Commentary on "Association Between Hepatic Steatosis With Significant Fibrosis and CAD Severity in Different Glucose Metabolic States: A CSCD-TCM plus Study". 《不同糖代谢状态下肝脂肪变性伴显著纤维化与冠心病严重程度的关系：CSCD-TCM联合研究》评论。

IF 2.7 3区医学

Angiology Pub Date : 2026-09-25 DOI: 10.1177/00033197261492879

Lin Fei, Tiantian Liu, Bin Xi, Feng Yang

引用次数: 0

Correlation Analysis Between Serum Lp-PLA2 and Platelet Activation Markers in Patients With Different Degrees of Coronary Artery Stenosis. 不同冠状动脉狭窄程度患者血清Lp-PLA2与血小板活化标志物的相关性分析

IF 2.7 3区医学

Angiology Pub Date : 2026-09-25 DOI: 10.1177/00033197261490730

Yang Wang, Zhanrong Zhu, Guo Xue, Xinyu Zhu, Ling Yu

{"title":"Correlation Analysis Between Serum Lp-PLA2 and Platelet Activation Markers in Patients With Different Degrees of Coronary Artery Stenosis.","authors":"Yang Wang, Zhanrong Zhu, Guo Xue, Xinyu Zhu, Ling Yu","doi":"10.1177/00033197261490730","DOIUrl":"https://doi.org/10.1177/00033197261490730","url":null,"abstract":"Coronary artery disease (CAD) is characterized by complex interactions between vascular inflammation and platelet activation. This study aimed to investigate the association between serum lipoprotein-associated phospholipase A2 (Lp-PLA2) and platelet activation markers in CAD patients with different degrees of coronary stenosis. A cross-sectional observational study was conducted among 209 patients with CAD confirmed by coronary angiography. Patients were stratified into mild, moderate, and severe stenosis groups according to Gensini score tertiles. Serum levels of Lp-PLA2, P-selectin, platelet factor 4 (PF4), and β-thromboglobulin (β-TG) were measured, and their associations were evaluated using correlation analysis and multivariable linear regression. Lp-PLA2 and platelet activation markers showed progressively higher levels in patients with more severe coronary stenosis. Significant positive correlations between Lp-PLA2 and PF4 (r = .570), P-selectin (r = .503), and β-TG (r = .450) were observed in patients with severe stenosis (all P < .001). After adjustment for cardiovascular risk factors and high-sensitivity C-reactive protein (hs-CRP), Lp-PLA2 remained independently associated with platelet activation markers. These findings indicate that circulating Lp-PLA2 levels are associated with platelet activation status in CAD, particularly among patients with severe coronary stenosis. Future prospective studies are needed to clarify the temporal relationship and clinical significance of these associations.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197261490730"},"PeriodicalIF":2.7,"publicationDate":"2026-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149036337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0