AngiologyPub Date : 2026-10-01Epub Date: 2025-11-30DOI: 10.1177/00033197251399867
Mohammad Reza Movahed
{"title":"Strongly Recommend Percutaneous Coronary Intervention for Any Chronic Total Occlusion (CTO) Based on a Secondary Analysis is Very Misleading.","authors":"Mohammad Reza Movahed","doi":"10.1177/00033197251399867","DOIUrl":"10.1177/00033197251399867","url":null,"abstract":"","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"1204"},"PeriodicalIF":2.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145647295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2026-10-01Epub Date: 2025-11-16DOI: 10.1177/00033197251392665
Dimitrios A Chatzelas, Theodosia N Zampaka, Georgios V Tsamourlidis, Vasiliki-Elisavet P Stratinaki, Ioanna I Kiose, Georgios A Pitoulias, Apostolos G Pitoulias
{"title":"Can Amputation be Justified for Extremity Arteriovenous Malformations? A Case Report and Scoping Review of Literature.","authors":"Dimitrios A Chatzelas, Theodosia N Zampaka, Georgios V Tsamourlidis, Vasiliki-Elisavet P Stratinaki, Ioanna I Kiose, Georgios A Pitoulias, Apostolos G Pitoulias","doi":"10.1177/00033197251392665","DOIUrl":"10.1177/00033197251392665","url":null,"abstract":"<p><p>Arteriovenous malformations (AVMs) are rare, congenital, high-flow vascular anomalies, that may become aggressive and threatening, especially in the extremities. We present the case of a 42-year-old male with a congenital AVM of the non-dominant hand, who presented at our emergency department with spontaneous, life-threatening hemorrhage. Despite previous embolization attempts, the lesion had progressed to Schobinger stage III. The patient underwent emergent mid-forearm amputation, which successfully controlled the hemorrhage and provided significant pain relief. Two years postoperatively, he remains free of recurrence, with excellent functional and psychological recovery. A comprehensive literature review was also performed, highlighting the role of amputation as a last-resort, but sometimes life-saving, intervention in advanced extremity AVMs. Although embolization and surgical resection remain the cornerstones of treatment, amputation may be necessary in cases of intractable symptoms, recurrent complications, or failure of other therapies. A multidisciplinary, patient-centered approach is critical for decision-making and optimal long-term outcomes.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"1110-1115"},"PeriodicalIF":2.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145534270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Elevated Uric Acid/Albumin Ratio as a Predictor of Carotid Plaque in Patients With Coronary Artery Disease: A Chinese CSCD-TCM Plus Study.","authors":"Qian Zhang, Jingyu Sheng, Shuo Wang, Ziqin Lai, Fanfan Liu, Boya Zhang, Shan Gao, Chunquan Yu","doi":"10.1177/00033197251392662","DOIUrl":"10.1177/00033197251392662","url":null,"abstract":"<p><p>The present study explored the association between serum uric acid/albumin ratio (UAR) and carotid artery plaque (CAP) in cases (n = 12 481) with coronary heart disease (CHD). Participants were stratified by UAR quartiles. Logistic regression analysis was used to analyze the association between the UAR and CAP. The relationship between the UAR and carotid plaques according to sex, age, blood pressure, and blood lipid groups was also assessed. Results showed that UAR was significantly associated with CAP (odds ratio [OR]: 1.03; 95% confidence interval [CI]: 1.02-1.05). The correlation between UAR and the presence of carotid plaque was strong in both females (OR: 1.03; 95% CI: 1.01-1.06) and males (OR: 1.03; 95% CI: 1.00-1.06). Patients aged ≥60 (OR: 1.60; 95% CI: 1.34-1.90) had a higher risk for carotid plaque at the Q4 UAR level than those <60. Hypertensive patients showed higher carotid plaque risk at Q4 UAR (OR: 1.46; 95% CI: 1.20-1.78) than normotensives. The correlation between UAR and the presence of carotid plaque was greater in dyslipidemic patients (OR: 1.06; 95% CI: 1.02-1.10) than in normolipidemic patients (OR: 1.03; 95% CI: 1.01-1.05). These results confirm a significant association between UAR and CAP, most pronounced in patients aged ≥60 or with hypertension/dyslipidemia.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"1161-1169"},"PeriodicalIF":2.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145562391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2026-10-01DOI: 10.1177/00033197261492091
Yuchen Wang, Na Duan
{"title":"Research Progress on Mechanisms and Pharmacological Interventions of Coronary Artery Calcification.","authors":"Yuchen Wang, Na Duan","doi":"10.1177/00033197261492091","DOIUrl":"https://doi.org/10.1177/00033197261492091","url":null,"abstract":"<p><p>Coronary artery calcification (CAC) is a critical determinant of cardiovascular morbidity and mortality. Current research identifies CAC as an active biological process driven by vascular smooth muscle cell (VSMC) osteogenic transdifferentiation, chronic inflammation, oxidative stress, and metabolic dysregulation. These pathological changes are orchestrated by complex signaling networks that promote mineral deposition in the arterial wall. Emerging pharmacological interventions, including denosumab, vitamin K2, and SNF472, have demonstrated potential in attenuating CAC progression by targeting these specific pathways. Conversely, widely prescribed medications such as statins exhibit complex, dual effects on calcification, necessitating careful clinical evaluation. This review synthesizes the core molecular mechanisms underlying CAC and critically evaluates current and emerging pharmacological strategies, providing mechanistic insights to guide future precision management.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197261492091"},"PeriodicalIF":2.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149103391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2026-10-01Epub Date: 2025-12-08DOI: 10.1177/00033197251392666
Song Peng Ang, Jia Ee Chia, Jose Iglesias, Chayakrit Krittanawong, Jonathan A Tangsrivimol, Umair Khalid, Debabrata Mukherjee
{"title":"Sex-Specific Trends and Differences in Clinical Outcomes Among Young Patients With Ischemic Stroke.","authors":"Song Peng Ang, Jia Ee Chia, Jose Iglesias, Chayakrit Krittanawong, Jonathan A Tangsrivimol, Umair Khalid, Debabrata Mukherjee","doi":"10.1177/00033197251392666","DOIUrl":"10.1177/00033197251392666","url":null,"abstract":"<p><p>Stroke in young adults poses significant public health challenges, with an increasing incidence globally. This study examines sex-specific trends, clinical outcomes, and healthcare resource utilization in young adults with ischemic stroke in the United States. Using the National Inpatient Sample from 2016 to 2021, we identified ischemic stroke hospitalizations in adults aged 18 to 44 years. We compared baseline characteristics, comorbidities, and outcomes between sexes, assessing trends with weighted regression and multivariate logistic regression to adjust for confounders; 168 310 hospitalizations were analyzed: 86 705 (51.5%) men and 81 605 (48.5%) women. Men had a higher prevalence of cardiovascular comorbidities, including hypertension, hyperlipidemia, and smoking while women had higher rates of diabetes, hypothyroidism, and anemia. Women had a lower adjusted odds ratio (aOR) for mortality (0.84, 95% CI: 0.75-0.94, <i>P</i> = .001) and acute kidney injury (0.50, 95% CI: 0.47-0.54, <i>P</i> < .001). The incidence of ischemic stroke/100 000 hospitalizations increased steadily over 6 years for both sexes, though men consistently showed higher rates. This study highlights sex-specific differences in ischemic stroke among young adults, with women showing better outcomes despite unique risk profiles. Targeted interventions addressing modifiable risk factors are needed to reduce stroke burden, particularly in young men.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"1134-1141"},"PeriodicalIF":2.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145706987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2026-10-01Epub Date: 2026-02-21DOI: 10.1177/00033197261427068
Işık Tekin
{"title":"Letter: Endothelial Health in Carotid Stenting: Bridging Inflammation and Activation With CAR and EASIX.","authors":"Işık Tekin","doi":"10.1177/00033197261427068","DOIUrl":"10.1177/00033197261427068","url":null,"abstract":"","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"1210-1211"},"PeriodicalIF":2.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146257119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2026-10-01Epub Date: 2025-12-27DOI: 10.1177/00033197251390099
Cemalettin Akman, Ahmet Güner, Regayip Zehir, Barış Şimşek, Ahmet Öz, Mustafa Kamil Yemiş, Mehmet Akif Erdöl, Ebru Serin, Veysel Ozan Tanık, Mustafa Ferhat Keten, Ezgi Merve Çelik, Berkay Serter, Büşra Çörekçioğlu, Kaan Gökçe, Koray Çiloğlu, Abdullah Doğan, Ezgi Gültekin Güner, Saner Bahadır Gök, Ali Nural, Ahmet Ceyhun Cebeci, Ali Yaşar Kılınç, Ziya Apaydın, Abdullah Kadir Dolu, Mustafa Sarı, Mert Evlice, Emre Paçacı, Hicaz Zencirkıran Ağuş, Azmican Kaya, Koray Demirci, Aybüke Şimşek, Fatih Furkan Bedir, Yusuf Yiğit Yılmaz, Adnan Özel, Esin Karakaya, Ali Öztürk, Hande Uysal, Sinem Deniz Çakal, Kudret Keskin, Ahmet Arif Yalçın, Fatih Uzun
{"title":"Comparison of Different Side Branch Ballooning Following Provisional Stenting in Coronary Bifurcation Lesion-Related STEMI.","authors":"Cemalettin Akman, Ahmet Güner, Regayip Zehir, Barış Şimşek, Ahmet Öz, Mustafa Kamil Yemiş, Mehmet Akif Erdöl, Ebru Serin, Veysel Ozan Tanık, Mustafa Ferhat Keten, Ezgi Merve Çelik, Berkay Serter, Büşra Çörekçioğlu, Kaan Gökçe, Koray Çiloğlu, Abdullah Doğan, Ezgi Gültekin Güner, Saner Bahadır Gök, Ali Nural, Ahmet Ceyhun Cebeci, Ali Yaşar Kılınç, Ziya Apaydın, Abdullah Kadir Dolu, Mustafa Sarı, Mert Evlice, Emre Paçacı, Hicaz Zencirkıran Ağuş, Azmican Kaya, Koray Demirci, Aybüke Şimşek, Fatih Furkan Bedir, Yusuf Yiğit Yılmaz, Adnan Özel, Esin Karakaya, Ali Öztürk, Hande Uysal, Sinem Deniz Çakal, Kudret Keskin, Ahmet Arif Yalçın, Fatih Uzun","doi":"10.1177/00033197251390099","DOIUrl":"10.1177/00033197251390099","url":null,"abstract":"<p><p>The present study retrospectively assessed clinical outcomes of proximal optimization technique (POT)-kissing-POT (PKP) and POT-side-POT (PSP) in ST-segment elevation myocardial infarction (STEMI) patients with culprit coronary bifurcation lesion (CBL) following a provisional stenting (PS). This large-scale multicenter (n = 10) study included STEMI patients with culprit CBLs who underwent PKP or PSP following PS. The primary endpoint was defined as the major adverse cardiac events (MACE; cardiac death, target vessel myocardial infarction [TVMI], or clinically driven target lesion revascularization [TLR]). Consecutive patients (n = 596; male: 491 [82.3%], mean age: 58.1 ± 11.7 years) were included. The study cohort was divided into 2 groups: PKP (n = 386) and PSP (n = 210). In the overall population, mid-term MACE (hazard ratio [HR]: 0.921, <i>P</i> = .461) did not differ in individuals with CBL-related STEMI treated with either PKP or PSP. The frequency of main vessel-TLR (0% vs 30%, <i>P</i> = .001) and main vessel-TVMI (0% vs 20%, <i>P</i> = .014) were significantly lower in the PKP group in the left main bifurcation localization. Diabetes mellitus (HR: 2.628, <i>P</i> < .001), high SYNTAX score (HR: 1.081, <i>P</i> < .001), and bifurcation localization (HR: 2.109, <i>P</i> = .014) were found to be independent predictors of MACE. In the overall population, risk-adjusted MACE rates for culprit CBLs were comparable between both techniques.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"1151-1160"},"PeriodicalIF":2.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145843434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2026-10-01Epub Date: 2026-01-12DOI: 10.1177/00033197251415227
De-Gang Mo, Li Zhuang
{"title":"Letter: SIRI Facilitates Risk Stratification and Prognostication in Coronary Artery Disease.","authors":"De-Gang Mo, Li Zhuang","doi":"10.1177/00033197251415227","DOIUrl":"10.1177/00033197251415227","url":null,"abstract":"","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"1198"},"PeriodicalIF":2.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145951195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}