Angiology最新文献_第10页

Cardiovascular Oncology: Consensus Statements Are Still Lacking to Improve the Management of Side-Effects of Old and New Chemotherapeutic Agents. 心血管肿瘤学：在改进新旧化疗药物副作用管理方面仍缺乏共识声明。

IF 2.7 3区医学

Angiology Pub Date : 2026-09-01 Epub Date: 2025-07-29 DOI: 10.1177/00033197251356583

Antonio V Sterpetti, Francesca Miceli, Alessia Di Girolamo, Immacolata Iannone, Paolo Sapienza, Luca Di Marzo

{"title":"Cardiovascular Oncology: Consensus Statements Are Still Lacking to Improve the Management of Side-Effects of Old and New Chemotherapeutic Agents.","authors":"Antonio V Sterpetti, Francesca Miceli, Alessia Di Girolamo, Immacolata Iannone, Paolo Sapienza, Luca Di Marzo","doi":"10.1177/00033197251356583","DOIUrl":"10.1177/00033197251356583","url":null,"abstract":"Significant advances in diagnostic methods and better life-expectancy have resulted in increased number of patients with cardiovascular diseases and cancer. Elderly patients are at risk for both diseases, and the treatment of patients with cardiovascular and oncologic problems represents a daily clinical challenge, considering the heterogeneity of clinical situations. The present review underlines the complexity of cardiovascular oncology. In the last 5 years >18 new drugs against cancer, with possible cardiovascular side-effects, were approved by the Food and Drug Administration. Several new drugs are under evaluation in multicenter prospective studies, and some of these agents have potential cardiovascular side-effects. This review analyzes the difficulties for cardiovascular specialists to keep updated regarding the possible side-effects of new chemotherapeutic agents. The analysis of the mechanisms involved in cancer occurrence and progression are a field of research in continuous development with new discoveries, and technologies applied at developing effective chemotherapeutic drugs. Several recommendations have been proposed by the American Heart Association and European Society of Cardiology, promoting the need for close collaboration between cardiologists, surgeons, and oncologists. It is important to develop strategies to support training in cardiovascular oncology.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"945-960"},"PeriodicalIF":2.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144726948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association Between Hepatic Steatosis With Significant Fibrosis and CAD Severity in Different Glucose Metabolic States: A CSCD-TCM ^plus Study. 不同糖代谢状态下肝脂肪变性伴显著纤维化与CAD严重程度的关系：一项CSCD-TCM联合研究。

IF 2.7 3区医学

Angiology Pub Date : 2026-09-01 Epub Date: 2025-11-12 DOI: 10.1177/00033197251382388

Yixuan Yin, Tong Yang, Yijia Liu, YuTing Li, FengMin Liu, RuiYing Guo, Qina Lei, Xing Zhang, Shu Liu, Shan Gao, Lin Li, ChunQuan Yu, Qiang Xu, Rongrong Yang, Mingchi Luo

{"title":"Association Between Hepatic Steatosis With Significant Fibrosis and CAD Severity in Different Glucose Metabolic States: A CSCD-TCM plus Study.","authors":"Yixuan Yin, Tong Yang, Yijia Liu, YuTing Li, FengMin Liu, RuiYing Guo, Qina Lei, Xing Zhang, Shu Liu, Shan Gao, Lin Li, ChunQuan Yu, Qiang Xu, Rongrong Yang, Mingchi Luo","doi":"10.1177/00033197251382388","DOIUrl":"10.1177/00033197251382388","url":null,"abstract":"Nonalcoholic fatty liver disease frequently coexists with diabetes (DM), and both are associated with an increased risk of coronary heart disease (CHD). The effect of nonalcoholic fatty liver disease progression or regression on the severity of coronary artery disease (CAD) in patients with CHD or DM remains unclear. In this multicenter study, 3126 patients with CHD, hepatic steatosis and fibrosis were assessed using the hepatic steatosis index (HSI) and fibrosis-4 index. CAD severity was evaluated using coronary angiography. After adjusting for confounders, hepatic steatosis (HSI > 36) was found to be associated with an increased risk of multivessel CAD. In patients with both hepatic steatosis and significant fibrosis (HSI > 36, fibrosis-4 index ≥ 1.3), the risk was further elevated (odds ratio [OR]: 1.596; 95% confidence interval [CI]: 1.245-2.046), with a stronger association in patients with DM (OR: 1.988; 95% CI: 1.041-3.835). Hepatic steatosis and/or significant fibrosis were associated with CAD severity, especially in individuals with both CHD and DM.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"1016-1026"},"PeriodicalIF":2.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145493997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Letter: Metabolic Dysfunction-Associated Steatotic Liver Disease: A Silent Whisper to the Heart? 信函：代谢功能障碍相关的脂肪变性肝病：对心脏的无声耳语？

IF 2.7 3区医学

Angiology Pub Date : 2026-09-01 Epub Date: 2025-12-30 DOI: 10.1177/00033197251407732

Emir Muzurović, Ivana Kraljević, Špela Volčanšek

引用次数: 0

Evaluation of Long-Term Cardiovascular Outcomes in Patients With NSTEMI Undergoing Percutaneous Coronary Intervention: Impact of Comorbid Peripheral Artery Disease. 非stemi患者经皮冠状动脉介入治疗的长期心血管预后评估：共病外周动脉疾病的影响

IF 2.7 3区医学

Angiology Pub Date : 2026-09-01 Epub Date: 2025-10-24 DOI: 10.1177/00033197251382399

Çağrı Zorlu, Yağmur Demirezen, Kayıhan Karaman, Metin Karayakali, Ataç Çelik

{"title":"Evaluation of Long-Term Cardiovascular Outcomes in Patients With NSTEMI Undergoing Percutaneous Coronary Intervention: Impact of Comorbid Peripheral Artery Disease.","authors":"Çağrı Zorlu, Yağmur Demirezen, Kayıhan Karaman, Metin Karayakali, Ataç Çelik","doi":"10.1177/00033197251382399","DOIUrl":"10.1177/00033197251382399","url":null,"abstract":"The present study evaluated the long-term prognostic impact of comorbid peripheral artery disease (PAD) in non-ST-elevation myocardial infarction (NSTEMI) patients undergoing percutaneous coronary intervention (PCI). We analyzed data from 1245 NSTEMI patients who underwent PCI between 2013 and 2022. PAD was identified from electronic health records based on an ankle-brachial index <0.9 or prior lower extremity revascularization. The primary outcome was major adverse cardiovascular events (MACE), including all-cause mortality, recurrent myocardial infarction, stroke, and heart failure hospitalization (mean follow-up: 8.2 years). Kaplan-Meier survival analysis and Cox proportional hazards regression were adjusted for age, gender, diabetes, hypertension, and creatinine levels. Of 1245 patients, 312 (25.1%) had PAD and were older (68.4 ± 9.2 vs 62.7 ± 10.1 years, P < .001) and had higher rates of diabetes (48% vs 32%, P = .002) and hypertension (76% vs 61%, P = .01). MACE occurred in 42.3% of PAD patients versus 25.6% in those without PAD (P < .001). Kaplan-Meier analysis showed reduced MACE-free survival in PAD patients (log-rank P < .001). Cox regression confirmed PAD as an independent predictor of MACE (hazard ratio: 1.78, 95% CI 1.45-2.19, P < .001). In NSTEMI patients post-PCI, PAD significantly increased long-term MACE risk, replicating worse outcomes observed in polyvascular disease and underscoring the need for enhanced risk stratification of this cohort.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"1062-1067"},"PeriodicalIF":2.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145367464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reperfusion for Proximal Left Circumflex Artery Chronic Total Occlusion Benefits Patients With Diabetes: A Retrospective Cohort Study. 慢性全闭塞左旋近端动脉再灌注对糖尿病患者有益：一项回顾性队列研究。

IF 2.7 3区医学

Angiology Pub Date : 2026-09-01 Epub Date: 2025-10-09 DOI: 10.1177/00033197251377325

Fei Yuan, Maomao Liu, Yunfeng Yan, Nan Liu, Shuzheng Lyu

{"title":"Reperfusion for Proximal Left Circumflex Artery Chronic Total Occlusion Benefits Patients With Diabetes: A Retrospective Cohort Study.","authors":"Fei Yuan, Maomao Liu, Yunfeng Yan, Nan Liu, Shuzheng Lyu","doi":"10.1177/00033197251377325","DOIUrl":"10.1177/00033197251377325","url":null,"abstract":"Diabetes with chronic total arterial occlusion carries a poor prognosis. Little is known about patients with diabetes and stable left circumflex artery (LCX) chronic total occlusion (LCX-CTO). We aimed to determine whether stable LCX-CTO should be recanalized in patients with diabetes. We analyzed patients with LCX-CTO, diabetes, and stable clinical symptoms (i.e., silent ischemia or symptomatic stable angina), who underwent successful revascularization (SR) or medical therapy (MT). The primary endpoint was major adverse cardiac events. Propensity score-matched analyses and Cox regression were performed. The proximal LCX-CTO subpopulation was analyzed. A stratified subgroup analysis was conducted for the primary endpoint. We enrolled 620 patients, stratified into MT (448, 72.26%) and SR groups (172, 27.74%). After a median 44-month follow-up, univariate and multivariable models showed that SR offered no clinical benefits regarding major adverse cardiac events (adjusted hazard ratio [aHR]: 0.860, 95% confidence interval [CI]: 0.520-1.423, P = .558). This was consistent for other clinical endpoints as well. However, in the subpopulation with proximal LCX-CTO, SR was superior in terms of cardiac (aHR: 0.284, 95% CI: 0.082-0.984) and all-cause mortality (aHR: 0.455, 95% CI: 0.167-1.239). Revascularization should be attempted in patients with diabetes who have proximal LCX-CTO.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"988-998"},"PeriodicalIF":2.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145249403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of Serum Uric Acid and CRP/Albumin Ratio With Contrast-Induced Nephropathy in Acute Myocardial Infarction Patients. 血清尿酸和CRP/白蛋白比值与急性心肌梗死患者造影剂肾病的关系

IF 2.7 3区医学

Angiology Pub Date : 2026-09-01 Epub Date: 2025-09-29 DOI: 10.1177/00033197251376082

Arzu Akgül, Çağatay Tunca, Alperen Taş, Mehmet Deniz Aylı

{"title":"Association of Serum Uric Acid and CRP/Albumin Ratio With Contrast-Induced Nephropathy in Acute Myocardial Infarction Patients.","authors":"Arzu Akgül, Çağatay Tunca, Alperen Taş, Mehmet Deniz Aylı","doi":"10.1177/00033197251376082","DOIUrl":"10.1177/00033197251376082","url":null,"abstract":"Contrast-induced nephropathy (CIN) significantly increases morbidity and mortality among acute myocardial infarction (MI) patients undergoing coronary angiography (CAG). This study evaluated the predictive value of serum uric acid (SUA) and C-reactive protein/albumin ratio (CAR) for CIN development. A retrospective analysis included 1326 acute MI patients who underwent CAG between November 2022 and January 2024. CIN occurred in 119 patients (9.0%). Higher SUA (5.60 vs 4.60 mg/dL, P < .001) and CAR (2.79 vs 2.15, P = .004) were significantly associated with CIN. Multivariate analysis confirmed SUA (Odds Ratio [OR]: 1.577, P < .001) and contrast volume (OR: 1.014, P < .001) as independent predictors. Receiver Operating Characteristic (ROC) analysis identified optimal SUA cutoff at 4.9 mg/dL (sensitivity 67.7%, specificity 68.1%). The predictive value of SUA was stronger among diabetic patients. Additionally, SUA positively correlated with CAR (r = .41, P < .001). A simplified risk score incorporating SUA, CAR, contrast volume, diabetes, and age effectively stratified CIN risk. Elevated SUA levels and high CAR independently predict CIN in acute MI patients, enhancing clinical risk stratification and guiding preventive strategies.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"1027-1035"},"PeriodicalIF":2.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145184560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Response to Letter Re: "Prognostic Value of the Naples Score in Older Patients With Acute Coronary Syndrome". 回复：“那不勒斯评分在老年急性冠脉综合征患者中的预后价值”。

IF 2.7 3区医学

Angiology Pub Date : 2026-09-01 Epub Date: 2026-02-20 DOI: 10.1177/00033197261425814

Ebru Serin, Sinan Şahin, Ahmet Gürdal, Mert Sarilar, Erol Kalender, Hasan Degirmenci, Kudret Keskin

引用次数: 0

The Relation Between CHA2DS2-VASc Score, Initial TIMI Flow Grades and In-Hospital Mortality in Patients Presenting with Acute Myocardial Infarction. 急性心肌梗死患者CHA2DS2-VASc评分、初始TIMI血流分级与住院死亡率的关系

IF 2.7 3区医学

Angiology Pub Date : 2026-09-01 Epub Date: 2025-10-20 DOI: 10.1177/00033197251378891

Funda Ozlem Pamuk, Hatice Mediha Kına, Esra Dönmez, Ceren Yağmur Doğru, Hatice Selçuk

{"title":"The Relation Between CHA2DS2-VASc Score, Initial TIMI Flow Grades and In-Hospital Mortality in Patients Presenting with Acute Myocardial Infarction.","authors":"Funda Ozlem Pamuk, Hatice Mediha Kına, Esra Dönmez, Ceren Yağmur Doğru, Hatice Selçuk","doi":"10.1177/00033197251378891","DOIUrl":"10.1177/00033197251378891","url":null,"abstract":"The CHA2DS2-VASc score includes classical risk factors (e.g., Congestive heart failure/Left ventricle dysfunction, Hypertension, Age, Diabetes mellitus, Stroke/Transient ischemic attack/Thromboembolism, Vascular disease and Sex) for coronary artery disease. We investigated the association between initial thrombolysis in myocardial infarction (TIMI) flow of the culprit artery and CHA2DS2-VASc score and in-hospital clinical outcomes in patients presenting with acute myocardial infarction (AMI). Initial and postprocedural TIMI flow grades were recorded in patients hospitalized with first diagnosis of AMI. The initial TIMI flow grades and CHA2DS2VASC scores were compared with the post-procedural TIMI flow grades. Patients (n = 750) were included retrospectively; 56.7% was in the low flow (TIMI 0-1) and 43.3% was in the high flow (TIMI 2-3) group. The CHA2DS2-VASc score was higher (P < .001) in the low flow group. The best CHA2DS2-VASc score cut-off value was 3 to predict initial TIMI flow. Median CHA2DS2-VASc score was 4 in-hospital mortality group (P < .001) and this score was an independent predictor of in-hospital mortality. The CHA2DS2-VASc score was an independent predictor of low initial TIMI flow and in-hospital mortality. Patients with high preprocedural CHA2DS2-VASc tended to have low coronary flow grades and higher mortality rates.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"1036-1043"},"PeriodicalIF":2.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145336347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Response to Letter Re: The Perfusion Index May be an Accurate Tool for Predicting the Progression of Ischemia in Patients With Peripheral Arterial Disease. 灌注指数可能是预测外周动脉疾病患者缺血进展的准确工具。

IF 2.7 3区医学

Angiology Pub Date : 2026-08-25 DOI: 10.1177/00033197261481347

Hiroyoshi Komai, Yuka Kitaoka, Nobuko Yamamoto, Islam Atta, Masato Ohno, Noriyuki Miyama, Noriyasu Morikage, Tadaaki Koyama

引用次数: 0

Response to Letter Entitled "Perfusion Index as a Rule-Out Marker in Peripheral Arterial Disease". 对题为“灌注指数作为外周动脉疾病的排除指标”的信件的回应。

IF 2.7 3区医学

Angiology Pub Date : 2026-08-25 DOI: 10.1177/00033197261481354

Hiroyoshi Komai, Yuka Kitaoka, Nobuko Yamamoto, Islam Atta, Masato Ohno, Noriyuki Miyama, Noriyasu Morikage, Tadaaki Koyama

引用次数: 0