AngiologyPub Date : 2024-08-27DOI: 10.1177/00033197241278547
Ming Li, Xu Li
{"title":"Letter: CXCL1 Index May Act as a Potential Biomarker of Plaque Instability in Patients With Carotid Stenosis.","authors":"Ming Li, Xu Li","doi":"10.1177/00033197241278547","DOIUrl":"https://doi.org/10.1177/00033197241278547","url":null,"abstract":"","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197241278547"},"PeriodicalIF":2.6,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142078935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2024-08-26DOI: 10.1177/00033197241276271
Gerfried Pesau, Bernhard Zierfuss, Clemens Hoebaus, Renate Koppensteiner, Gerit-Holger Schernthaner
{"title":"Letter: Answer to \"Trefoil Factor-3 and Peripheral Artery Disease: Reason or Result\".","authors":"Gerfried Pesau, Bernhard Zierfuss, Clemens Hoebaus, Renate Koppensteiner, Gerit-Holger Schernthaner","doi":"10.1177/00033197241276271","DOIUrl":"https://doi.org/10.1177/00033197241276271","url":null,"abstract":"","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197241276271"},"PeriodicalIF":2.6,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142071879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2024-08-23DOI: 10.1177/00033197241278131
Alberto Farinetti, Antonio Manenti, Anna Vittoria Mattioli
{"title":"Letter: Long COVID in Patients With Peripheral Arterial Disease; the Need for Further Research.","authors":"Alberto Farinetti, Antonio Manenti, Anna Vittoria Mattioli","doi":"10.1177/00033197241278131","DOIUrl":"https://doi.org/10.1177/00033197241278131","url":null,"abstract":"","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197241278131"},"PeriodicalIF":2.6,"publicationDate":"2024-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142043847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2024-08-22DOI: 10.1177/00033197241274825
Serdar Gökhan Nurkoç, Turab Yakışan
{"title":"Mean Platelet Volume/Platelet Count Ratio and Dipper/Non-Dipper Hypertensive Patients.","authors":"Serdar Gökhan Nurkoç, Turab Yakışan","doi":"10.1177/00033197241274825","DOIUrl":"https://doi.org/10.1177/00033197241274825","url":null,"abstract":"<p><p>There is an interaction between mean platelet volume (MPV), platelet count (PC), inflammation, and platelet reactivity. The present study evaluated the relationship between the MPV/PC ratio and blood pressure (BP) using 24 h ambulatory BP monitoring (ABPM). A total of 720 patients (male: 291) were included in the study. Based on the ABPM outcomes, they were divided into two groups: dipper hypertensive (<i>n</i> = 350; male: 136) and non-dipper hypertensive (<i>n</i> = 370; male: 155). Peripheral venous blood samples obtained at admission were used for PC and MPV calculations. Both groups displayed identical clinical characteristics. Non-dipper hypertensives had a higher MPV/PC ratio than dipper hypertensives [0.044; (0.036-0.055); 0.036 (0.030-0.042); <i>P</i> < .001]. According to receiver operating characteristic (ROC) curve analysis, the optimal cut-off value of the MPV/PC ratio for predicting non-dipper patterns in hypertensive patients was 0.040 (area under the curve [AUC]: 0.726, <i>P</i> < .001). Sensitivity was 64.1% and specificity was 64.3%. The MPV/PC ratio may represent mechanisms involved in increasing cardiovascular risk in non-dipper hypertensives compared with dipper hypertensives.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197241274825"},"PeriodicalIF":2.6,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142035090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2024-08-22DOI: 10.1177/00033197241276977
Qingbo Wang, Yunshan Jiang, Peijian Wang
{"title":"Letter: Stress Hyperglycemia Ratio Is Associated With Poor Prognosis in Ischemic Stroke.","authors":"Qingbo Wang, Yunshan Jiang, Peijian Wang","doi":"10.1177/00033197241276977","DOIUrl":"https://doi.org/10.1177/00033197241276977","url":null,"abstract":"","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197241276977"},"PeriodicalIF":2.6,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142016200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Value of lncRNA CASC19 in Myocardial Infarction and its Role in Myocardial Infarction-Induced Cardiomyocyte Apoptosis.","authors":"Zhou Lan, Pengye Liu, Peng Tuo, Yuguang Gao, Ling Zhao, Qingyu Huang","doi":"10.1177/00033197241273348","DOIUrl":"https://doi.org/10.1177/00033197241273348","url":null,"abstract":"<p><p>To explore the effect of long non-coding RNA cancer susceptibility 19 (lncRNA CASC19) on the activity, apoptosis, and oxidative stress response of cardiomyocytes, so as to assess the clinical relevance and molecular mechanism of CASC19 in myocardial infarction (MI). CASC19 level was determined by using real-time quantitative polymerase chain reaction (RT-qPCR). MI model was constructed using hypoxia induction, and rat cardiomyocytes H9c2 were divided into control group, MI group, MI small interference negative control (MI-si-NC) group, MI-si-CASC19 group, MI-si-CASC19+microRNA-NC (miR-NC) group, and MI-si-CASC19+miR-218-5p inhibitor group. Tetramethylazolium salt colorimetric method and flow cytometry were used to evaluate cell activity and apoptotic capacity. Cellular oxidative stress was evaluated using malondialdehyde and superoxide dismutase kits. The relationship between CASC19 and miR-218-5p was confirmed by using dual-luciferase activity assay. CASC19 levels were enhanced in MI patients and hypoxia-induced cardiomyocytes. Downregulating CASC19 promoted the proliferation, while suppressed apoptosis and oxidative stress in the MI cell model. Moreover, low expression of miR-218-5p reversed the promotion of proliferation and inhibition of apoptosis and oxidative stress in MI cell models by silencing CASC19. Briefly, CASC19 may serve as a diagnostic marker for MI by sponging miR-218-5p to inhibit apoptosis and oxidative stress in cardiomyocytes and promote cell survival.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197241273348"},"PeriodicalIF":2.6,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142003472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2024-08-19DOI: 10.1177/00033197241273331
Gündüz Durmuş, Mehmet Baran Karataş, Murat Gökalp, Semih Eren, Ahmet Ceyhun Cebeci, Ali Nural, Elif Hatipoğlu, Altuğ Osken, Mehmet Karaca, Ahmet Zengin
{"title":"Increased Serum CRP-Albumin Ratio is Independently Associated With In-Stent Restenosis After Carotid Artery Stenting.","authors":"Gündüz Durmuş, Mehmet Baran Karataş, Murat Gökalp, Semih Eren, Ahmet Ceyhun Cebeci, Ali Nural, Elif Hatipoğlu, Altuğ Osken, Mehmet Karaca, Ahmet Zengin","doi":"10.1177/00033197241273331","DOIUrl":"https://doi.org/10.1177/00033197241273331","url":null,"abstract":"<p><p>Atherosclerotic stenosis of the carotid artery contributes significantly to ischemic strokes. This study investigates the correlation between the C-reactive protein (CRP) to albumin ratio (CAR) and in-stent restenosis (ISR) in patients (<i>n</i> = 529) undergoing carotid artery stenting. Patients were categorized based on ISR occurrence. Cox regression analyses were performed to identify independent predictors of ISR. The ISR rate was 10.3%. Laboratory analysis revealed higher levels of uric acid, CRP, and CAR in the ISR group. Cox regression identified CAR as an independent predictor of ISR (Hazard ratio (HR): 1.13, 95% CI: 1.03-1.24, <i>P</i> = .01), along with diabetes and smoking. A CAR cut-off of 0.28 predicted ISR with 93% sensitivity and 89% specificity (Area under the curve (AUC): 0.945, 95% CI: 0.923-0.963, <i>P</i> < .001). This study establishes a significant association between CAR and ISR in carotid artery stenting patients. The inflammatory response, indicated by CAR, emerges as a crucial factor in ISR development. The study contributes valuable insights into predicting and preventing ISR, emphasizing the potential of CAR as a prognostic biomarker. This easily accessible and cost-effective biomarker could enhance ISR prediction and guide preventive strategies for high-risk patients.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197241273331"},"PeriodicalIF":2.6,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141999371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2024-08-18DOI: 10.1177/00033197241274824
Aslan Erdogan, Omer Genc, Eyüp Ozkan, Muhammed M Goksu, Ersin Ibisoglu, Mehmet N Bilen, Ahmet Guler, Ali Karagoz
{"title":"\"Reply to Letter to the Editor for Research Paper Entitled : Impact of Naples prognostic Score at Admission on In-Hospital and Follow-Up Outcomes Among Patients With ST-Segment Elevation Myocardial Infarction\".","authors":"Aslan Erdogan, Omer Genc, Eyüp Ozkan, Muhammed M Goksu, Ersin Ibisoglu, Mehmet N Bilen, Ahmet Guler, Ali Karagoz","doi":"10.1177/00033197241274824","DOIUrl":"https://doi.org/10.1177/00033197241274824","url":null,"abstract":"","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197241274824"},"PeriodicalIF":2.6,"publicationDate":"2024-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141995185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}