AngiologyPub Date : 2026-09-01Epub Date: 2025-11-12DOI: 10.1177/00033197251395818
Yesim Eylev Akboga, Mehmet Kadri Akboga
{"title":"Letter: Predictors of Contrast-Induced Nephropathy in Vulnerable Populations.","authors":"Yesim Eylev Akboga, Mehmet Kadri Akboga","doi":"10.1177/00033197251395818","DOIUrl":"10.1177/00033197251395818","url":null,"abstract":"","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"1068"},"PeriodicalIF":2.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145501767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2026-09-01Epub Date: 2025-10-07DOI: 10.1177/00033197251379122
Laith Alhuneafat, Omar Obeidat, Mohammed Ayyad, Ahmad Alayyat, Waqas Rasheed, Ahmad Maaita, Fares Ghanem, Zaid Shahrori, Anas Alameh, Ahmad Al-Abdouh, Pedro Villablanca, Ahmad Jabri
{"title":"Inpatient Tricuspid Valve Transcatheter and Surgical Inpatient Outcomes: A Propensity Matched Analysis.","authors":"Laith Alhuneafat, Omar Obeidat, Mohammed Ayyad, Ahmad Alayyat, Waqas Rasheed, Ahmad Maaita, Fares Ghanem, Zaid Shahrori, Anas Alameh, Ahmad Al-Abdouh, Pedro Villablanca, Ahmad Jabri","doi":"10.1177/00033197251379122","DOIUrl":"10.1177/00033197251379122","url":null,"abstract":"<p><p>Tricuspid regurgitation (TR) is a common valvular disorder associated with significant morbidity and mortality. While surgical repair (STVr) and replacement (STVR) are established treatments, transcatheter tricuspid valve interventions (TTVI) have emerged as less invasive alternatives. The present study compared inpatient outcomes of TTVI, STVr, and STVR using data from the National Inpatient Sample (2011-2020). A retrospective analysis identified 1830 TTVI, 76 747 STVr, and 19 625 STVR procedures. After propensity score matching, 1655 TTVI-STVr and 1286 TTVI-STVR patient pairs were included. Compared with surgery, TTVI was associated with significantly lower in-hospital mortality (2.4% vs 7.0% STVr; 2.3% vs 11.6% STVR; <i>P</i> < .001), shorter hospital stays (6.9 vs 15.6 days STVr; 7.2 vs 17.6 days STVR; <i>P</i> < .001), and reduced costs. TTVI was associated with lower in-hospital mortality, fewer complications, and shorter hospital stays compared with surgical interventions in this analysis. Given the limitations of retrospective studies, including selection bias and lack of long-term follow-up, these findings require cautious interpretation. Prospective studies are needed to compare the efficacy and durability of TTVI versus surgery for TR.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"999-1006"},"PeriodicalIF":2.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145243589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2026-09-01Epub Date: 2025-11-12DOI: 10.1177/00033197251395828
Mesut Engin, Cihan Aydın, Hasan Arı
{"title":"Letter: Reperfusion of Proximal Left Circumflex Artery in Diabetic Chronic Total Occlusion Patients.","authors":"Mesut Engin, Cihan Aydın, Hasan Arı","doi":"10.1177/00033197251395828","DOIUrl":"10.1177/00033197251395828","url":null,"abstract":"","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"1069"},"PeriodicalIF":2.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145501764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2026-09-01Epub Date: 2025-10-05DOI: 10.1177/00033197251376086
Li Ke-Xin, Luo Yi-Chen, Huang Hao, Chen Yan-Ting
{"title":"SRY-Box Transcription Factor 18 Links Inflammation to Calcific Aortic Valve Progression via CD68 and NF-κB p65.","authors":"Li Ke-Xin, Luo Yi-Chen, Huang Hao, Chen Yan-Ting","doi":"10.1177/00033197251376086","DOIUrl":"10.1177/00033197251376086","url":null,"abstract":"<p><p>This study investigated SOX18's role in calcific aortic valve disease (CAVD). Aortic valve specimens from 67 patients undergoing valve replacement were stratified into control (n = 18), mild (n = 20), and severe calcification (n = 29) groups based on Alizarin Red staining. Immunohistochemistry revealed SOX18 expression localized to valve interstitial cells (VICs), with significantly higher levels in calcified versus control valves (<i>P</i> < .001). Elevated SOX18 was particularly associated with the inflammatory factors CD68 and Nuclear Factor-kappa B (NF-κB) p65, suggesting a potential link between SOX18, inflammation and CAVD progression. These findings highlight SOX18 as a possible mediator in valvular calcification.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"981-987"},"PeriodicalIF":2.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145231464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2026-09-01Epub Date: 2025-11-06DOI: 10.1177/00033197251384344
Yan Zhu, Yun-Sheng Wang, Gui-Ping Zhang, Fang Ma, Jin-Xiang Xia, Hu Lian, Yong-Hong Cao, Rong Zhang, Jun Ye, Wu Dai
{"title":"Association of Liver Fat Content With Carotid Endothelial Function in Patients With Newly Diagnosed Type 2 Diabetes Mellitus and Pre-Diabetes Mellitus.","authors":"Yan Zhu, Yun-Sheng Wang, Gui-Ping Zhang, Fang Ma, Jin-Xiang Xia, Hu Lian, Yong-Hong Cao, Rong Zhang, Jun Ye, Wu Dai","doi":"10.1177/00033197251384344","DOIUrl":"10.1177/00033197251384344","url":null,"abstract":"<p><p>This study aimed to compare carotid atherosclerotic indicators among patients with newly diagnosed type 2 diabetes mellitus (NT2DM), pre-diabetes mellitus (PDM), and healthy controls (HCs), and to investigate associations between nonalcoholic fatty liver disease (NAFLD) and carotid atherosclerosis. A total of 240 participants were enrolled (120 NT2DM, 60 PDM, and 60 HCs). Liver fat content (LFC) was assessed using proton magnetic resonance spectroscopy ([<sup>1</sup>H]-MRS). Carotid intima-media thickness (CIMT) and carotid pulse wave velocity (PWV) at the beginning (BS-PWV) and end of systole (ES-PWV) were measured by ultrasonography. The levels of LFC were significantly higher in NT2DM (14.57% ± 6.49%) and PDM (11.44% ± 5.62%) than in HCs (5.73% ± 4.08%; <i>P</i>=.000). The prevalence of NAFLD was 66.7% in NT2DM, 38.3% in PDM, and 25.0% in HCs. CIMT, BS-PWV, and ES-PWV were significantly elevated in NT2DM compared with PDM and HCs (all <i>P</i> < .05). Multiple linear regression (MLR) analyses showed LFC and triglycerides were strong contributors to both BS-PWV and ES-PWV. Elevated LFC and NAFLD prevalence in NT2DM, together with their associations with carotid atherosclerosis, suggest a potential link between NAFLD and cardiovascular disease in T2DM.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"1007-1015"},"PeriodicalIF":2.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145450182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Triglyceride-Glucose Index Mediated by Metabolic Burden Predicts Cardiovascular Events in Patients With Complex Coronary Lesions: A Prospective Cohort Study.","authors":"Zhihao Zheng, Jining He, Yanjun Song, Shanshan Shi, Min Yang, Chenxi Song, Dong Yin, Qiuting Dong, Wenjia Zhang, Kefei Dou","doi":"10.1177/00033197251390139","DOIUrl":"10.1177/00033197251390139","url":null,"abstract":"<p><p>This prospective cohort study evaluated the prognostic value of the triglyceride-glucose (TyG) index and its metabolic mediation pathways in 16 499 patients with complex coronary lesions (American College of Cardiology/American Heart Association type B2/C) undergoing percutaneous coronary intervention (PCI). Over a median 3-year follow-up, 535 patients (3.2%) experienced cardiovascular (CV) events. Patients in the highest TyG tertile (T3: >9.10) demonstrated a 2.442-fold increased CV risk compared with the lowest tertile (T1: <8.63; 95% CI 1.923-3.102, <i>P</i> < .001), with a significant dose-response relationship (<i>P</i>-trend < .001). Structural equation modeling revealed that metabolic burden (hypertension, dyslipidemia, type 2 diabetes mellitus) mediated 50.0% of TyG-associated risk (indirect effect <i>P</i> = .038). TyG index exhibited superior predictive accuracy for CV events compared with the TG/HDL-C ratio (area under the curve [AUC] 0.617 vs 0.577, <i>P</i> = .004), though their combination did not significantly improve discrimination over TyG alone (△AUC = 0.001, <i>P</i> = .694). Type 2 diabetes mellitus accounted for 62.3% of the mediation effect, surpassing hypertension (20.8%), and dyslipidemia (16.9%). These findings establish the TyG index as an independent predictor of CV outcomes in complex coronary lesions, with metabolic comorbidities explaining half its prognostic impact. Integration of TyG-driven metabolic phenotyping may optimize risk stratification and targeted interventions in high-risk PCI populations.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"1051-1061"},"PeriodicalIF":2.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145538815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2026-09-01Epub Date: 2025-10-28DOI: 10.1177/00033197251390173
Gökhan Ceyhun
{"title":"Letter: Carotid Disease and Cerebrovascular Risk Following TAVI: Insights and Remaining Questions.","authors":"Gökhan Ceyhun","doi":"10.1177/00033197251390173","DOIUrl":"10.1177/00033197251390173","url":null,"abstract":"","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"1079"},"PeriodicalIF":2.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145376056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2026-09-01Epub Date: 2025-10-24DOI: 10.1177/00033197251383351
Ebru Serin, Sinan Şahin, Ahmet Gürdal, Mert Sarilar, Erol Kalender, Hasan Değirmenci, Kudret Keskin
{"title":"Prognostic Value of the Naples Score in Older Patients With Acute Coronary Syndrome.","authors":"Ebru Serin, Sinan Şahin, Ahmet Gürdal, Mert Sarilar, Erol Kalender, Hasan Değirmenci, Kudret Keskin","doi":"10.1177/00033197251383351","DOIUrl":"10.1177/00033197251383351","url":null,"abstract":"<p><p>The Naples prognostic score (NPS) consists of the neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio (LMR), serum albumin levels, and total cholesterol (TC) levels. This study hypothesizes that the NPS may predict mortality in older patients with acute coronary syndrome (ACS). We conducted a retrospective study including 380 patients diagnosed with ACS at our hospital from May 2015 to December 2022. Older hospitalized patients (≥75 years of age) with ACS were divided by NPS into 2 groups: low NPS (0-2) and high NPS (3-4). The median follow-up time was 23 months. The primary outcome was long-term mortality from the day of admission. In-hospital mortality was 15.8% (n = 60 patients), and long-term mortality was 50.5% (n = 192). In the high-NPS group two, a higher rate of long-term mortality was observed (group 2, n = 123 [58%] vs group 1, n = 69 [41.1%], <i>P</i> < .001). In contrast, gender, diabetes mellitus, hypertension, SYNTAX score, or in-hospital mortality were not associated with NPS. In this study, these results demonstrated that high NPS values may be a predictor of all-cause mortality.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"1044-1050"},"PeriodicalIF":2.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145367397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}