{"title":"Red Palms' Syndrome and Red Fingers' Syndrome: A Mini Review.","authors":"Salvino Bilancini, Massimo Lucchi, Sandro Tucci, Federica Pomella, Giulia Vittori, Pierluigi Edgard Mollo, Giusto Trevisan","doi":"10.1177/00033197231185459","DOIUrl":"10.1177/00033197231185459","url":null,"abstract":"<p><p>Red palms syndrome consists of an intense redness on the palms of the hands and, occasionally, the soles of the feet. This infrequent condition may be primary or secondary. The primary forms are either familial or sporadic. They are always benign and do not require treatment. The secondary forms may have a poor prognosis related to the underlying disease, for which early identification and treatment are imperative. Red fingers syndrome is also rare. It manifests as a persistent redness on the fingers or toes pulp. It is typically secondary either to infectious diseases like human immunodeficiency virus, hepatitis C virus and chronic hepatitis B or to Myeloproliferative Disorders, such as Thrombocythemia and Polycythemia vera. Manifestations spontaneously regress over months or years without trophic alterations. Treatment is limited to that of the underlying condition. Aspirin has been shown effective in Myeloproliferative Disorders.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"717-724"},"PeriodicalIF":2.6,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9755284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of the Atherogenic Index of Plasma to Predict All-Cause Mortality in Elderly With Acute Coronary Syndrome: A Long-Term Follow-Up.","authors":"Özgür Selim Ser, Kudret Keskin, Gökhan Çetinkal, Betül Balaban Kocaş, Hakan Kilci, Erol Kalender, Furkan Dolap, Tümay Celbiş Geçit, Cüneyt Kocaş, Kadriye Kılıçkesmez","doi":"10.1177/00033197241279587","DOIUrl":"https://doi.org/10.1177/00033197241279587","url":null,"abstract":"<p><p>The Atherogenic Index of Plasma (AIP) is associated with coronary artery disease (CAD) and acute coronary syndrome (ACS), but the relationship between AIP and ACS in elderly patients remains unclear. We investigated the prognostic capability of AIP for in-hospital and long-term mortality in elderly patients with ACS undergoing coronary angiography (CA). We analyzed 627 patients with ACS over 75 years of age who were admitted to our clinic between April 2015 and December 2022 and underwent CA. The primary clinical endpoints were in-hospital, 30-day, 1-year, and long-term mortality. The median follow-up time was 27 months. AIP was defined as log (triglyceride/high-density lipoprotein cholesterol). In-hospital mortality rates for patients with AIP ≤.1 and AIP >.1 were 4.7% and 17.6% (<i>P</i> < .001), 30-day mortality rates were 8.7% and 32.2% (<i>P</i> = .01), 1-year mortality rates were 12.1% and 45.1% (<i>P</i> < .001), and long-term mortality rates were 47.3% and 67.5% (<i>P</i> < .001), respectively. Multivariate Cox regression analysis revealed AIP, age, left ventricle ejection fraction (LVEF), admission creatinine, and Killip ≥2 as independent predictors for long-term mortality. AIP can predict in-hospital and long-time all-cause mortality in elderly patients with ACS undergoing CA. Age, LVEF, admission creatinine, and Killip ≥2 are additional factors that predict long-term all-cause mortality.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197241279587"},"PeriodicalIF":2.6,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2024-08-27DOI: 10.1177/00033197241278923
Plinio Cirillo, Luigi Di Serafino, Maria Scalamogna, Gennaro De Rosa, Paolo Calabrò, Emilia Antonucci, Paolo Gresele, Gualtiero Palareti, Giuseppe Patti, Vittorio Pengo, Pasquale Pignatelli, Rossella Marcucci
{"title":"ACEF vs PARIS score in Predicting Cardiovascular Events in Patients With Acute Coronary Syndrome: Insights From the START ANTIPLATELET Registry.","authors":"Plinio Cirillo, Luigi Di Serafino, Maria Scalamogna, Gennaro De Rosa, Paolo Calabrò, Emilia Antonucci, Paolo Gresele, Gualtiero Palareti, Giuseppe Patti, Vittorio Pengo, Pasquale Pignatelli, Rossella Marcucci","doi":"10.1177/00033197241278923","DOIUrl":"https://doi.org/10.1177/00033197241278923","url":null,"abstract":"<p><p>Several scores can predict clinical outcomes of patients with Acute Coronary Syndromes (ACS). The validated PARIS (Patterns of Non-Adherence to Anti-Platelet Regimen in Stented Patients) score is poorly used in clinical practice because it needs items that are not always easily available. The ACEF (Age, Creatinine, and Ejection Fraction) score is more attractive because it only includes three items. We compared these scores to risk-stratify ACS patients enrolled into the START (Survey on anticoagulated pAtients RegisTer)-ANTIPLATELET registry. ACS patients who completed 1-year follow-up (<i>n</i> = 1171) were grouped in tertiles (low, medium, and high-risk) according to their ACEF/PARIS scores. Primary endpoints were: one-year MACCE (major adverse cardiac and cerebrovascular events: death, non-fatal myocardial infarction, stroke or target vessel revascularization) and NACE (net adverse cardiac and cerebrovascular events): MACCE plus major bleeding). MACCE incidence was higher in the high-risk tertile (15%) VS low/medium (3/7 %) risk tertiles (<i>P</i> < .001). NACE incidence in the high-risk tertile was 24% VS low/medium (9/15 %) risk tertiles (<i>P</i> < .001), independently of the risk score used<b>.</b> The ACEF score has similar accuracy as the validated PARIS score for the estimation of ischemic/bleeding risk. Thereby, we strongly suggest its use in clinical practice to risk-stratify ACS patients and select optimal therapeutic strategies.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197241278923"},"PeriodicalIF":2.6,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142078934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2024-08-27DOI: 10.1177/00033197241278547
Ming Li, Xu Li
{"title":"Letter: CXCL1 Index May Act as a Potential Biomarker of Plaque Instability in Patients With Carotid Stenosis.","authors":"Ming Li, Xu Li","doi":"10.1177/00033197241278547","DOIUrl":"https://doi.org/10.1177/00033197241278547","url":null,"abstract":"","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197241278547"},"PeriodicalIF":2.6,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142078935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2024-08-26DOI: 10.1177/00033197241276271
Gerfried Pesau, Bernhard Zierfuss, Clemens Hoebaus, Renate Koppensteiner, Gerit-Holger Schernthaner
{"title":"Letter: Answer to \"Trefoil Factor-3 and Peripheral Artery Disease: Reason or Result\".","authors":"Gerfried Pesau, Bernhard Zierfuss, Clemens Hoebaus, Renate Koppensteiner, Gerit-Holger Schernthaner","doi":"10.1177/00033197241276271","DOIUrl":"https://doi.org/10.1177/00033197241276271","url":null,"abstract":"","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197241276271"},"PeriodicalIF":2.6,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142071879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2024-08-23DOI: 10.1177/00033197241278131
Alberto Farinetti, Antonio Manenti, Anna Vittoria Mattioli
{"title":"Letter: Long COVID in Patients With Peripheral Arterial Disease; the Need for Further Research.","authors":"Alberto Farinetti, Antonio Manenti, Anna Vittoria Mattioli","doi":"10.1177/00033197241278131","DOIUrl":"https://doi.org/10.1177/00033197241278131","url":null,"abstract":"","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197241278131"},"PeriodicalIF":2.6,"publicationDate":"2024-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142043847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2024-08-22DOI: 10.1177/00033197241274825
Serdar Gökhan Nurkoç, Turab Yakışan
{"title":"Mean Platelet Volume/Platelet Count Ratio and Dipper/Non-Dipper Hypertensive Patients.","authors":"Serdar Gökhan Nurkoç, Turab Yakışan","doi":"10.1177/00033197241274825","DOIUrl":"https://doi.org/10.1177/00033197241274825","url":null,"abstract":"<p><p>There is an interaction between mean platelet volume (MPV), platelet count (PC), inflammation, and platelet reactivity. The present study evaluated the relationship between the MPV/PC ratio and blood pressure (BP) using 24 h ambulatory BP monitoring (ABPM). A total of 720 patients (male: 291) were included in the study. Based on the ABPM outcomes, they were divided into two groups: dipper hypertensive (<i>n</i> = 350; male: 136) and non-dipper hypertensive (<i>n</i> = 370; male: 155). Peripheral venous blood samples obtained at admission were used for PC and MPV calculations. Both groups displayed identical clinical characteristics. Non-dipper hypertensives had a higher MPV/PC ratio than dipper hypertensives [0.044; (0.036-0.055); 0.036 (0.030-0.042); <i>P</i> < .001]. According to receiver operating characteristic (ROC) curve analysis, the optimal cut-off value of the MPV/PC ratio for predicting non-dipper patterns in hypertensive patients was 0.040 (area under the curve [AUC]: 0.726, <i>P</i> < .001). Sensitivity was 64.1% and specificity was 64.3%. The MPV/PC ratio may represent mechanisms involved in increasing cardiovascular risk in non-dipper hypertensives compared with dipper hypertensives.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197241274825"},"PeriodicalIF":2.6,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142035090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2024-08-22DOI: 10.1177/00033197241276977
Qingbo Wang, Yunshan Jiang, Peijian Wang
{"title":"Letter: Stress Hyperglycemia Ratio Is Associated With Poor Prognosis in Ischemic Stroke.","authors":"Qingbo Wang, Yunshan Jiang, Peijian Wang","doi":"10.1177/00033197241276977","DOIUrl":"https://doi.org/10.1177/00033197241276977","url":null,"abstract":"","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197241276977"},"PeriodicalIF":2.6,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142016200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Value of lncRNA CASC19 in Myocardial Infarction and its Role in Myocardial Infarction-Induced Cardiomyocyte Apoptosis.","authors":"Zhou Lan, Pengye Liu, Peng Tuo, Yuguang Gao, Ling Zhao, Qingyu Huang","doi":"10.1177/00033197241273348","DOIUrl":"https://doi.org/10.1177/00033197241273348","url":null,"abstract":"<p><p>To explore the effect of long non-coding RNA cancer susceptibility 19 (lncRNA CASC19) on the activity, apoptosis, and oxidative stress response of cardiomyocytes, so as to assess the clinical relevance and molecular mechanism of CASC19 in myocardial infarction (MI). CASC19 level was determined by using real-time quantitative polymerase chain reaction (RT-qPCR). MI model was constructed using hypoxia induction, and rat cardiomyocytes H9c2 were divided into control group, MI group, MI small interference negative control (MI-si-NC) group, MI-si-CASC19 group, MI-si-CASC19+microRNA-NC (miR-NC) group, and MI-si-CASC19+miR-218-5p inhibitor group. Tetramethylazolium salt colorimetric method and flow cytometry were used to evaluate cell activity and apoptotic capacity. Cellular oxidative stress was evaluated using malondialdehyde and superoxide dismutase kits. The relationship between CASC19 and miR-218-5p was confirmed by using dual-luciferase activity assay. CASC19 levels were enhanced in MI patients and hypoxia-induced cardiomyocytes. Downregulating CASC19 promoted the proliferation, while suppressed apoptosis and oxidative stress in the MI cell model. Moreover, low expression of miR-218-5p reversed the promotion of proliferation and inhibition of apoptosis and oxidative stress in MI cell models by silencing CASC19. Briefly, CASC19 may serve as a diagnostic marker for MI by sponging miR-218-5p to inhibit apoptosis and oxidative stress in cardiomyocytes and promote cell survival.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197241273348"},"PeriodicalIF":2.6,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142003472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2024-08-19DOI: 10.1177/00033197241273331
Gündüz Durmuş, Mehmet Baran Karataş, Murat Gökalp, Semih Eren, Ahmet Ceyhun Cebeci, Ali Nural, Elif Hatipoğlu, Altuğ Osken, Mehmet Karaca, Ahmet Zengin
{"title":"Increased Serum CRP-Albumin Ratio is Independently Associated With In-Stent Restenosis After Carotid Artery Stenting.","authors":"Gündüz Durmuş, Mehmet Baran Karataş, Murat Gökalp, Semih Eren, Ahmet Ceyhun Cebeci, Ali Nural, Elif Hatipoğlu, Altuğ Osken, Mehmet Karaca, Ahmet Zengin","doi":"10.1177/00033197241273331","DOIUrl":"https://doi.org/10.1177/00033197241273331","url":null,"abstract":"<p><p>Atherosclerotic stenosis of the carotid artery contributes significantly to ischemic strokes. This study investigates the correlation between the C-reactive protein (CRP) to albumin ratio (CAR) and in-stent restenosis (ISR) in patients (<i>n</i> = 529) undergoing carotid artery stenting. Patients were categorized based on ISR occurrence. Cox regression analyses were performed to identify independent predictors of ISR. The ISR rate was 10.3%. Laboratory analysis revealed higher levels of uric acid, CRP, and CAR in the ISR group. Cox regression identified CAR as an independent predictor of ISR (Hazard ratio (HR): 1.13, 95% CI: 1.03-1.24, <i>P</i> = .01), along with diabetes and smoking. A CAR cut-off of 0.28 predicted ISR with 93% sensitivity and 89% specificity (Area under the curve (AUC): 0.945, 95% CI: 0.923-0.963, <i>P</i> < .001). This study establishes a significant association between CAR and ISR in carotid artery stenting patients. The inflammatory response, indicated by CAR, emerges as a crucial factor in ISR development. The study contributes valuable insights into predicting and preventing ISR, emphasizing the potential of CAR as a prognostic biomarker. This easily accessible and cost-effective biomarker could enhance ISR prediction and guide preventive strategies for high-risk patients.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197241273331"},"PeriodicalIF":2.6,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141999371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}