IF 2.6 3区医学

Angiology Pub Date : 2025-04-01 Epub Date: 2023-11-07 DOI: 10.1177/00033197231213674

Jiaqi Wang, Feifei Zhang, Litian Liu, Man Gao, Xuelian Song, Yingxiao Li, Yi Dang, Xiaoyong Qi

{"title":"Prognostic Value of GRACE Risk Score Combined With Systemic Immune-Inflammation Index in Patients With ST-Segment Elevation Myocardial Infarction After Percutaneous Coronary Intervention.","authors":"Jiaqi Wang, Feifei Zhang, Litian Liu, Man Gao, Xuelian Song, Yingxiao Li, Yi Dang, Xiaoyong Qi","doi":"10.1177/00033197231213674","DOIUrl":"10.1177/00033197231213674","url":null,"abstract":"The Global Registry of Acute Coronary Events (GRACE) score and the systemic immune-inflammation index (SII) were used independently to predict adverse outcomes in patients with ST-elevation myocardial infarction (STEMI). In this study, 1041 patients with STEMI were divided into 4 groups based on GRACE scores and optimal cutoff values for SII. SII was positively correlated with GRACE score (r = 0.164; P < .001). SII (HR, hazard ratio: 2.051; 95%CI: 1.249-3.368; P = .005) and GRACE score (HR: 7.625; 95%CI: 3.692-15.746; P < .001) were independent risk predictors of short-term major adverse cardiovascular events (MACEs). Taking the low SII+low GRACE group as the reference group, the short-term MACE HR of the high SII+high GRACE group was 40.470 (95%CI: 5.547-295.253). Comparing the area under the curve, the combined use of SII and GRACE scores can significantly improve the prediction efficiency of short-term MACE compared with the single use of SII and GRACE scores. In conclusion, SII may be positively correlated with GRACE score, and the combination of the two accurately predicted the occurrence of short-term MACE in STEMI patients after percutaneous coronary intervention (PCI).","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"349-360"},"PeriodicalIF":2.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71477384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intravenous Iron for Heart Failure: Updated Systematic Review and Meta-Analysis. 静脉注射铁治疗心力衰竭：最新系统综述和荟萃分析。

IF 2.6 3区医学

Angiology Pub Date : 2025-04-01 Epub Date: 2023-11-02 DOI: 10.1177/00033197231213181

Witina Techasatian, Yoshito Nishimura, Manasawee Tanariyakul, Clarke Morihara, Chinnawat Arayangkool, Alexander Settle, Noppawit Aiumtrakul, Jakrin Kewcharoen

{"title":"Intravenous Iron for Heart Failure: Updated Systematic Review and Meta-Analysis.","authors":"Witina Techasatian, Yoshito Nishimura, Manasawee Tanariyakul, Clarke Morihara, Chinnawat Arayangkool, Alexander Settle, Noppawit Aiumtrakul, Jakrin Kewcharoen","doi":"10.1177/00033197231213181","DOIUrl":"10.1177/00033197231213181","url":null,"abstract":"While the administration of intravenous (IV) iron to those with heart failure has been implicated to be associated with a possible reduction in hospitalizations and improvement in symptoms, a recent large multicenter trial only showed modest benefits in reducing hospitalization, necessitating the updated systematic review. We conducted a systematic review and meta-analysis, searching the MEDLINE and EMBASE database until January 9, 2023. Outcomes included total heart failure hospitalizations, first heart failure hospitalization, six-minute walk test (6MWT) distance, and incidence of infection. There were 13 studies with 3410 participants (1,790 with IV iron). Pooled analysis that reported the incidence of cardiovascular death showed that patients with IV iron did not have significantly lower odds of cardiovascular death or first heart failure hospitalization. In contrast, those who received IV iron had significantly lower total heart failure hospitalization (pooled odds ratio (OR) 0.63, 95% confidence interval (CI) 0.44-0.90, I 2 59.0%, P = .017) and a composite of cardiovascular death and first heart failure hospitalization (pooled OR 0.55, 95% CI 0.47-0.64, I 2 0%, P = .656). While the efficacy is modest, IV iron therapy could be associated with reduced hospitalization for heart failure without significant adverse events.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"370-381"},"PeriodicalIF":2.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71420216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Symptomatic Upper Extremity Peripheral Artery Disease is Associated With Poor Outcomes and a Broad Spectrum of Etiologies. 有症状的上肢外周动脉疾病与不良预后和广泛的病因有关。

IF 2.6 3区医学

Angiology Pub Date : 2025-04-01 Epub Date: 2023-12-14 DOI: 10.1177/00033197231218332

Guillaume Armengol, Guillaume Goudot, Sébastien Miranda, Ygal Benhamou, Muriel Tafflet, Henri Guillet, Hélène Mortelette, Hervé Levesque, Emmanuel Messas, Tristan Mirault

{"title":"Symptomatic Upper Extremity Peripheral Artery Disease is Associated With Poor Outcomes and a Broad Spectrum of Etiologies.","authors":"Guillaume Armengol, Guillaume Goudot, Sébastien Miranda, Ygal Benhamou, Muriel Tafflet, Henri Guillet, Hélène Mortelette, Hervé Levesque, Emmanuel Messas, Tristan Mirault","doi":"10.1177/00033197231218332","DOIUrl":"10.1177/00033197231218332","url":null,"abstract":"The symptomatic upper extremity peripheral artery disease (sUE-PAD) is poorly studied compared with the lower extremity peripheral artery disease (LE-PAD). We aimed to describe sUE-PAD etiologies and outcomes at 2 years. From an observational survey conducted in two French tertiary hospitals, demographic characteristics, etiology, treatment, and outcomes during follow-up were collected on patients with ICD-10 I74.2 code (arterial thrombosis of the upper limbs). We identified 181 patients (53% male, 55 ± 17 years) with hypothenar hammer syndrome (13.8%), cardioembolism (13.3%), atheroma (12.7%), or connective tissue disease (10.5%). No etiology could be found for 16.0% of them. The amputation rate was 13.3%, and lasting symptoms remained at 21.3%. During follow-up, atrial fibrillation occurred in 1 patient and cancer in 4. At 2 years, 59 patients were lost to follow-up, 110 patients were alive, and 12 patients had died. Age and cancer were associated with death. sUE-PAD is not benign, with 20% impaired upper extremity outcome and 10% overall mortality at 2 years. Less frequent than LE-PAD, sUE-PAD presents different characteristics: more women, younger age, and a broad spectrum of etiologies. sUE-PAD requires thorough etiological assessment and is considered to be associated with a severe overall prognosis.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"382-390"},"PeriodicalIF":2.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138799446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mean Platelet Volume/Platelet Count Ratio and Dipper/Non-Dipper Hypertensive Patients. 平均血小板体积/血小板计数比和高血压患者的 "节食"/"不节食 "情况。

IF 2.6 3区医学

Angiology Pub Date : 2025-04-01 Epub Date: 2024-08-22 DOI: 10.1177/00033197241274825

Serdar Gökhan Nurkoç, Turab Yakışan

{"title":"Mean Platelet Volume/Platelet Count Ratio and Dipper/Non-Dipper Hypertensive Patients.","authors":"Serdar Gökhan Nurkoç, Turab Yakışan","doi":"10.1177/00033197241274825","DOIUrl":"10.1177/00033197241274825","url":null,"abstract":"There is an interaction between mean platelet volume (MPV), platelet count (PC), inflammation, and platelet reactivity. The present study evaluated the relationship between the MPV/PC ratio and blood pressure (BP) using 24 h ambulatory BP monitoring (ABPM). A total of 720 patients (male: 291) were included in the study. Based on the ABPM outcomes, they were divided into two groups: dipper hypertensive (n = 350; male: 136) and non-dipper hypertensive (n = 370; male: 155). Peripheral venous blood samples obtained at admission were used for PC and MPV calculations. Both groups displayed identical clinical characteristics. Non-dipper hypertensives had a higher MPV/PC ratio than dipper hypertensives [0.044; (0.036-0.055); 0.036 (0.030-0.042); P < .001]. According to receiver operating characteristic (ROC) curve analysis, the optimal cut-off value of the MPV/PC ratio for predicting non-dipper patterns in hypertensive patients was 0.040 (area under the curve [AUC]: 0.726, P < .001). Sensitivity was 64.1% and specificity was 64.3%. The MPV/PC ratio may represent mechanisms involved in increasing cardiovascular risk in non-dipper hypertensives compared with dipper hypertensives.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"323-329"},"PeriodicalIF":2.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142035090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Influence of Preoperative Right Ventricle to Pulmonary Arterial Coupling on Short- and Long-Term Prognosis in Patients Who Underwent Transcatheter Aortic Valve Implantation. 经导管主动脉瓣植入术患者术前右心室与肺动脉耦合对短期和长期预后的影响

IF 2.6 3区医学

Angiology Pub Date : 2025-04-01 Epub Date: 2024-02-11 DOI: 10.1177/00033197241232723

Aykun Hakgor, Basak Catalbas Kahraman, Atakan Dursun, Arzu Yazar, Umeyir Savur, Aysel Akhundova, Fatih Erkam Olgun, Melike Zeynep Kenger, Bilal Boztosun

{"title":"The Influence of Preoperative Right Ventricle to Pulmonary Arterial Coupling on Short- and Long-Term Prognosis in Patients Who Underwent Transcatheter Aortic Valve Implantation.","authors":"Aykun Hakgor, Basak Catalbas Kahraman, Atakan Dursun, Arzu Yazar, Umeyir Savur, Aysel Akhundova, Fatih Erkam Olgun, Melike Zeynep Kenger, Bilal Boztosun","doi":"10.1177/00033197241232723","DOIUrl":"10.1177/00033197241232723","url":null,"abstract":"The present study evaluated the prognostic significance of right ventricular-pulmonary arterial (RV-PA) coupling, assessed by the tricuspid annular plane systolic excursion to systolic pulmonary artery pressure (TAPSE/sPAP) ratio, in patients undergoing transcatheter aortic valve implantation (TAVI) for severe aortic stenosis (AS). This retrospective, single-center study involved 403 patients (mean age: 78.2 ± 8.4; 50.9% female). RV-PA coupling was categorized based on the pre-procedural TAPSE/sPAP ratio: severe uncoupling (≤0.32), moderate uncoupling (0.32-0.55), and normal coupling (>0.55). The study primary endpoints were in-hospital mortality and 2-year all-cause mortality. Multivariate logistic regression revealed that the TAPSE/sPAP ratio is an independent predictor of both in-hospital (adjusted OR: 0.61, 95% CI [0.44-0.84], P = .002) and 2-year mortality (adjusted OR: 0.69, 95% CI [0.56-0.85], P = .001). Severe uncoupling was strongly associated with increased 2-year mortality (adjusted OR: 3.92, 95% CI [1.67-9.20], P = .002). Our study establishes a significant association between reduced preoperative TAPSE/sPAP ratios and increased risks of both in-hospital and 2-year all-cause mortality in patients undergoing TAVI for severe AS. These results highlight the prognostic utility of evaluating RV-PA coupling. Incorporating this metric into preoperative risk stratification could potentially refine prognostic accuracy and inform clinical decision-making.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"340-348"},"PeriodicalIF":2.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139717297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-Term Evaluation of Revascularization Strategies for Medina 0.1.0 Left Main Bifurcation Lesions: The LM-CROSSOVER Registry. Medina 0.1.0左主干分叉病变血运重建策略的长期评估：LM-CROSSOVER注册。

IF 2.6 3区医学

Angiology Pub Date : 2025-04-01 Epub Date: 2023-11-01 DOI: 10.1177/00033197231213194

Ahmet Güner, Cemalettin Akman, Koray Çiloğlu, Kaan Gökçe, Fatih Uzun, Cemil Can, Serkan Kahraman, Ahmet Yaşar Çizgici, Arda Güler, Gökhan Demirci, Ezgi Gültekin Güner, Mehmet Ertürk

{"title":"Long-Term Evaluation of Revascularization Strategies for Medina 0.1.0 Left Main Bifurcation Lesions: The LM-CROSSOVER Registry.","authors":"Ahmet Güner, Cemalettin Akman, Koray Çiloğlu, Kaan Gökçe, Fatih Uzun, Cemil Can, Serkan Kahraman, Ahmet Yaşar Çizgici, Arda Güler, Gökhan Demirci, Ezgi Gültekin Güner, Mehmet Ertürk","doi":"10.1177/00033197231213194","DOIUrl":"10.1177/00033197231213194","url":null,"abstract":"The present study aimed to compare long-term outcomes of patients with Medina 0.1.0 left main (LM) bifurcation lesions treated by crossover stenting (COS) versus accurate ostial stenting (AOS). A total of 229 consecutive eligible patients with Medina 0.1.0 LM bifurcation lesions were enrolled and were stratified according to the stenting techniques. The primary end-point was major cardiovascular and cerebral events (MACCE), defined as the combination of all-cause death, target vessel related-myocardial infarction (MI), clinically driven target lesion revascularization (TLR), stroke, or stent thrombosis. COS and AOS were applied to 78 (34%) and 151 (66%) patients, respectively. During a mean of 40.6 ± 21.1 months of follow-up, the rate of MACCE (27.8 vs 12.8%; P=.007) was higher in patients treated with AOS than those treated with the COS technique, mainly driven by more frequent all-cause death (13.9 vs 3.8%, P = .013) and TLR (6.4 vs 15.9%; P = .029). In multivariable Cox regression analysis, AOS strategy was one of the independent predictors of MACCE (odds ratio: 2.166; 95% confidence interval, 1.080-4.340; P = .029). The current study suggests that COS was associated with a better long-term MACCE rate and lower all-cause mortality rate than AOS in patients with Medina 0.1.0 LM bifurcation disease.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"361-369"},"PeriodicalIF":2.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71420217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship Between CHA₂DS₂-VASc Score on Admission and In-Hospital Major Adverse Cardiovascular Events in Patients Diagnosed With ST-Elevation Myocardial Infarction. ST段抬高型心肌梗死患者入院时的CHA₂DS₂-VASc评分与院内主要不良心血管事件之间的关系。

IF 2.6 3区医学

Angiology Pub Date : 2025-04-01 Epub Date: 2024-08-12 DOI: 10.1177/00033197241273382

Duygu Inan, Duygu Genc, Barış Şimsek, Ozan Tanık, Evliya Akdeniz, Betül Korkmaz, Ufuk Aydogdu, Elif G Vatanoglu, Gönül Zeren, Büşra Ceylan, Çağdaş Yumurtaş, Gizem Yüksel, Levent Pay, Halil Tanboga, Can Y Karabay

{"title":"Relationship Between CHA₂DS₂-VASc Score on Admission and In-Hospital Major Adverse Cardiovascular Events in Patients Diagnosed With ST-Elevation Myocardial Infarction.","authors":"Duygu Inan, Duygu Genc, Barış Şimsek, Ozan Tanık, Evliya Akdeniz, Betül Korkmaz, Ufuk Aydogdu, Elif G Vatanoglu, Gönül Zeren, Büşra Ceylan, Çağdaş Yumurtaş, Gizem Yüksel, Levent Pay, Halil Tanboga, Can Y Karabay","doi":"10.1177/00033197241273382","DOIUrl":"10.1177/00033197241273382","url":null,"abstract":"The CHA₂DS₂-VASc (congestive heart failure, hypertension, age, diabetes mellitus, stroke, vascular disease, sex) scoring system, which includes conventional risk factors of coronary artery disease, was originally created to quantify the risk of thromboembolism in patients with atrial fibrillation. This study evaluated the usefulness of this score to predict adverse outcomes in STEMI (ST-elevation myocardial infarction) patients without atrial fibrillation. Primary end points were identified as MACE (major adverse cardiovascular events) which included in-hospital death or cerebrovascular accident. MACE rate was 10% (193 patients). The CHA₂DS₂-VASc score was an independent predictor of MACE (95% CI, 2.31 [1.37-3.9]; P = .0016). Other independent predictors of MACE included heart rate (95% CI, 1.56 [0.97-2.50]; P = .0242), admission Killip class (95% CI, 24.19 [10.74-54.46]; P < .0001), admission creatinine level (95% CI, 1.54 [1.10-2.16]; P = .0024), peak CK-MB level (95% CI, 1.63 [0.98-2.70]; P = .0001), and no-reflow (95% CI, 2.45 [1.25-4.80]; P = .0085). A nomogram was developed to estimate the risk of in-hospital adverse outcomes for STEMI patients. The CHA₂DS₂-VASc score was an independent predictor of MACE in STEMI patients. Linear analysis of CHA₂DS₂-VASc score without dichotomization was the main difference of this study from others.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"330-339"},"PeriodicalIF":2.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141915929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Letter: Can Mean Platelet Volume/Platelet Count Ratio be Implemented into Daily Clinical Decision Making Process? 致编辑的信：平均血小板体积/血小板计数比值能否应用于日常临床决策过程？

IF 2.6 3区医学

Angiology Pub Date : 2025-04-01 Epub Date: 2024-10-25 DOI: 10.1177/00033197241296467

Orhan Batur Şahin, Serkan Ünlü, Özden Seçkin Göbüt

引用次数: 0

The Role of the Receptor Activator of Nuclear Factor Kappa-B Ligand/Osteoprotegerin Ratio in Vascular Diseases: A Therapeutic Approach. 核因子卡巴-B 受体活化因子配体/骨保护蛋白比例在血管疾病中的作用：一种治疗方法

IF 2.6 3区医学

Angiology Pub Date : 2025-04-01 Epub Date: 2024-01-03 DOI: 10.1177/00033197231226275

Gizem Celebi Torabfam, Melis Hazal Porsuk

{"title":"The Role of the Receptor Activator of Nuclear Factor Kappa-B Ligand/Osteoprotegerin Ratio in Vascular Diseases: A Therapeutic Approach.","authors":"Gizem Celebi Torabfam, Melis Hazal Porsuk","doi":"10.1177/00033197231226275","DOIUrl":"10.1177/00033197231226275","url":null,"abstract":"Cardiovascular and bone diseases contribute independently to mortality and global health. The exact mechanisms involved in the pathophysiology shared between bone and vascular diseases are not well defined. Endothelial cells and osteoblasts communicate during osteogenesis, thus establishing a connection between angiogenesis and osteogenesis. One shared mechanism may involve osteoprotegerin (OPG) and its ligand Receptor Activator of NF-κB Ligand (RANKL). The RANKL/OPG ratio is an important modulator for the skeletal, immunological, and vascular systems. OPG levels are elevated due to either osteogenic causes or inflammatory responses in the vasculature. The data obtained from clinical and in vitro studies support the role of the RANKL/OPG ratio as a potential marker for the progression of endothelial damage. Therefore, determining the therapeutic approaches for the targeting RANKL/OPG ratio and evaluating its usage as a biomarker in cardiovascular and bone pathophysiology are needed. By integrating the protective and disease-causing role of OPG with its ligand, this review outlines the role of the RANKL/OPG ratio at the molecular level. We also consider targeted therapeutic approaches.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"309-322"},"PeriodicalIF":2.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139085657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Letter: Emerging Biomarkers in the No-reflow Phenomenon: Unveiling the Inflammatory Connection.

IF 2.6 3区医学

Angiology Pub Date : 2025-04-01 DOI: 10.1177/00033197251333222

Bülent Özlek, Süleyman Barutçu, Veysel Ozan Tanık

引用次数: 0

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