AngiologyPub Date : 2025-11-01Epub Date: 2025-02-02DOI: 10.1177/00033197241308368
Piotr Kazmierski, Piotr Szpakowski, Andrzej Glabinski
{"title":"Letter: CXCL1 Index May Act as a Potential Biomarker of Plaque Instability in Patients with Carotid Stenosis. Authors' Reply.","authors":"Piotr Kazmierski, Piotr Szpakowski, Andrzej Glabinski","doi":"10.1177/00033197241308368","DOIUrl":"10.1177/00033197241308368","url":null,"abstract":"","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"1035-1036"},"PeriodicalIF":2.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143077896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Trans-Carotid Artery Revascularization Versus Carotid Endarterectomy in Patients With Carotid Artery Disease: Systematic Review and Meta-analysis of 30-day Outcomes.","authors":"Georgios Loufopoulos, Vasiliki Manaki, Panagiotis Tasoudis, Nina-Rafailia Karela, Christophe Sénéchaud, Argirios Giannopoulos, Kiriakos Ktenidis, Konstantinos Spanos","doi":"10.1177/00033197241241788","DOIUrl":"10.1177/00033197241241788","url":null,"abstract":"<p><p>This systematic review and meta-analysis compared trans-carotid artery revascularization (TCAR) as an alternative approach to carotid endarterectomy (CEA) in patients with carotid artery disease. An electronic search was conducted using PubMed, Scopus, and Cochrane databases including comparative studies with patients who underwent either TCAR or CEA. This meta-analysis is according to the recommendations of the PRISMA statement. Eight studies met our eligibility criteria, incorporating 7,606 and 7,048 patients in the TCAR and CEA groups, respectively. Thirty-day mortality (odds ratio [OR]: 0.94, 95% confidence interval [CI]: 0.56-1.56, <i>P</i> = .81) and stroke (OR: 0.92, 95%CI 0.70-1.22, <i>P</i> = .57) were similar between the two groups, with low heterogeneity. The odds of myocardial infarction (OR: 1.79, 95% CI: 1.18-2.71, <i>P</i> = .01) and cranial nerve injury were significantly higher in patients undergoing CEA compared with TCAR (OR: 4.11, 95% CI: 2.59-6.51, <i>P</i> < .001). The subgroup analysis according to symptomatic pre-intervention status revealed no statistically significant difference regarding 30-day mortality (symptomatic OR: 0.91, 95% CI: 0.40-2.07, <i>P</i> = .82, asymptomatic OR: 0.93, 95% CI: 0.46-1.86, <i>P</i> = .83) and stroke (symptomatic OR: 0.88, 95% CI:0.47-1.64, <i>P</i> = .68, asymptomatic OR: 0.93, 95% CI: 0.64-1.35, <i>P</i> = .70). TCAR offers an alternative treatment for patients with carotid artery stenosis with comparable to CEA mortality and stroke rates during a 30-day post-operative period.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"928-936"},"PeriodicalIF":2.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140292615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2025-11-01Epub Date: 2025-09-17DOI: 10.1177/00033197251372771
Serdar Söner, Mehmet Özbek
{"title":"Predictors of ST-Segment Resolution and Its Relationship With Outcomes in Patients With ST-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention.","authors":"Serdar Söner, Mehmet Özbek","doi":"10.1177/00033197251372771","DOIUrl":"10.1177/00033197251372771","url":null,"abstract":"<p><p>ST-segment resolution (STR) is a critical parameter in ST-elevation myocardial infarction (STEMI) patients treated with primary percutaneous coronary intervention (pPCI). This study aimed to determine predictors of incomplete STR and their relationship with adverse cardiovascular outcomes. The study retrospectively included 508 consecutive STEMI patients who underwent pPCI in our hospital between January 2020 and December 2020. Patients with STR < 70% were included in the incomplete STR group (n = 182), and patients with STR ≥ 70% were included in the complete STR group (n = 326). Multivariable analysis identified in-stent restenosis (Odds ratio [OR] = 5.145), prolonged ischemic time (OR = 1.100), and left ventricular ejection fraction (LVEF; OR = 0.968) as independent predictors. Receiver operating curve (ROC) analysis found 4.5 hours of ischemic time and 49% LVEF as cutoff values. Kaplan-Meier analyses showed that incomplete STR correlated with greater 1- and 5-year mortality. In our study, the independent predictors of incomplete STR were LVEF, in-stent restenosis, and total ischemic time. In addition, incomplete STR was associated with in-stent restenosis, in-hospital, 1-year, and 5-year all-cause mortality. Our findings may prove useful in managing STEMI patients.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"1010-1018"},"PeriodicalIF":2.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145074180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2025-11-01Epub Date: 2024-06-12DOI: 10.1177/00033197241261453
Kosmas I Paraskevas, Mahmoud B Malas, Marc L Schermerhorn
{"title":"Transcarotid Artery Revascularization Versus Carotid Endarterectomy.","authors":"Kosmas I Paraskevas, Mahmoud B Malas, Marc L Schermerhorn","doi":"10.1177/00033197241261453","DOIUrl":"10.1177/00033197241261453","url":null,"abstract":"","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"925-927"},"PeriodicalIF":2.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141305248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2025-11-01Epub Date: 2024-06-21DOI: 10.1177/00033197241263399
Shengpeng Wang, Guannan Zhang
{"title":"Association Between Systemic Immune-Inflammation Index and Adverse Outcomes in Patients With Acute Coronary Syndrome: A Meta-Analysis.","authors":"Shengpeng Wang, Guannan Zhang","doi":"10.1177/00033197241263399","DOIUrl":"10.1177/00033197241263399","url":null,"abstract":"<p><p>The systemic immune-inflammation index (SII) has been developed for the risk prognostication of acute coronary syndrome (ACS) patients. This meta-analysis aimed to assess the value of SII for predicting adverse outcomes in ACS patients. Relevant studies were identified by searching the PubMed, Web of Science, and Embase databases. Studies that investigated the association of SII with all-cause mortality or major adverse cardiovascular events (MACEs) in ACS patients were eligible. The short-term outcomes were defined as adverse events occurring during the hospital and within 30 days. 11 studies with 16,596 patients were eligible for analysis. A random effect meta-analysis indicated that a higher SII level significantly predicted short-term death (hazard ratios [HR] 2.60; 95% confidence intervals [CI] 1.29-5.25) and long-term all-cause mortality (HR 2.40; 95% CI 1.25-4.59), even after adjusting for traditional confounding factors. Additionally, a higher SII level was also significantly associated with an increased risk of short-term MACEs (HR 1.61; 95% CI 1.28-2.03) and long-term MACEs (HR 2.43; 95% CI 1.74-3.40). These findings suggest that SII level has a strong prognostic value for both MACEs and all-cause mortality in patients with ACS. Determining the SII level has the potential to improve risk prognostication in ACS patients.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"946-954"},"PeriodicalIF":2.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141431226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2025-11-01Epub Date: 2024-06-18DOI: 10.1177/00033197241263384
Nikolaos Gouliopoulos, Gerasimos Siasos, Evangelos Oikonomou, Spyros Sapounas, Alexandros Rouvas, Apostolos C Ziogas, Marilita M Moschos, Dimitris Tousoulis
{"title":"The Association of Systemic Endothelial Dysfunction With Diffuse Diabetic Macular Edema.","authors":"Nikolaos Gouliopoulos, Gerasimos Siasos, Evangelos Oikonomou, Spyros Sapounas, Alexandros Rouvas, Apostolos C Ziogas, Marilita M Moschos, Dimitris Tousoulis","doi":"10.1177/00033197241263384","DOIUrl":"10.1177/00033197241263384","url":null,"abstract":"<p><p>Our aim was to assess whether systemic endothelial dysfunction, evaluated non-invasively by flow mediated dilation (FMD), is associated with diabetic macular edema (DME) and to determine if it is further impaired in patients with diffuse-DME. Consecutive patients (<i>n</i> = 84) with type-2 diabetes mellitus (T2DM) and diabetic retinopathy were enrolled. DME was not present in 38 (non-DME) and present in 46 patients; 25 with focal and 21 with diffuse-DME. No differences were detected between DME and non-DME groups regarding the clinical and demographic characteristics, except for the age of T2DM initiation (lower in non-DME). FMD values were significantly impaired in DME compared with non-DME patients, even after adjustment for multiple covariates (3.56 ± 1.03 vs 4.57 ± 1.25%, <i>P</i> = .003). Among DME patients, no differences were found concerning the clinical and demographic data, while FMD levels were significantly lower in diffuse-DME patients, compared with the focal-DME ones, regardless of the impact several confounders (2.88 ± 0.65 vs 4.08 ± 0.95%, <i>P</i> = .002). It is noteworthy that FMD values of non-DME and focal-DME patients did not differ significantly (4.52 ± 1.24 vs 4.21 ± 1.06%, <i>P</i> = .307). Moreover, among DME patients, impaired FMD was an independent predictor of diffuse-DME (odds ratio: 0.06, 95% CI 0.01-0.47, <i>P</i> = .007).</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"991-998"},"PeriodicalIF":2.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141417527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of the Atherogenic Index of Plasma to Predict All-Cause Mortality in Elderly With Acute Coronary Syndrome: A Long-Term Follow-Up.","authors":"Özgür Selim Ser, Kudret Keskin, Gökhan Çetinkal, Betül Balaban Kocaş, Hakan Kilci, Erol Kalender, Furkan Dolap, Tümay Celbiş Geçit, Cüneyt Kocaş, Kadriye Kılıçkesmez","doi":"10.1177/00033197241279587","DOIUrl":"10.1177/00033197241279587","url":null,"abstract":"<p><p>The Atherogenic Index of Plasma (AIP) is associated with coronary artery disease (CAD) and acute coronary syndrome (ACS), but the relationship between AIP and ACS in elderly patients remains unclear. We investigated the prognostic capability of AIP for in-hospital and long-term mortality in elderly patients with ACS undergoing coronary angiography (CA). We analyzed 627 patients with ACS over 75 years of age who were admitted to our clinic between April 2015 and December 2022 and underwent CA. The primary clinical endpoints were in-hospital, 30-day, 1-year, and long-term mortality. The median follow-up time was 27 months. AIP was defined as log (triglyceride/high-density lipoprotein cholesterol). In-hospital mortality rates for patients with AIP ≤.1 and AIP >.1 were 4.7% and 17.6% (<i>P</i> < .001), 30-day mortality rates were 8.7% and 32.2% (<i>P</i> = .01), 1-year mortality rates were 12.1% and 45.1% (<i>P</i> < .001), and long-term mortality rates were 47.3% and 67.5% (<i>P</i> < .001), respectively. Multivariate Cox regression analysis revealed AIP, age, left ventricle ejection fraction (LVEF), admission creatinine, and Killip ≥2 as independent predictors for long-term mortality. AIP can predict in-hospital and long-time all-cause mortality in elderly patients with ACS undergoing CA. Age, LVEF, admission creatinine, and Killip ≥2 are additional factors that predict long-term all-cause mortality.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"1019-1027"},"PeriodicalIF":2.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2025-11-01Epub Date: 2024-01-04DOI: 10.1177/00033197241226512
Pavel Poredos, Agata Stanek, Mariella Catalano, Vinko Boc
{"title":"Ankle-Brachial Index: Diagnostic Tool of Peripheral Arterial Disease and Predictor of Cardiovascular Risk-An Update of Current Knowledge.","authors":"Pavel Poredos, Agata Stanek, Mariella Catalano, Vinko Boc","doi":"10.1177/00033197241226512","DOIUrl":"10.1177/00033197241226512","url":null,"abstract":"<p><p>The ankle-brachial index (ABI) was introduced as a screening method for the diagnosis of lower extremity peripheral arterial disease (PAD). Later findings recognized ABI as a prognostic marker of adverse cardiovascular events due to its relation to atherosclerosis in other vascular territories. This narrative review aims to appraise the validity, reliability, and utility of ABI in the detection of PAD and the determination of global atherosclerotic cardiovascular risk. While the ABI value can be influenced by different physiological characteristics including age, sex, body position, and techniques used for ABI determination, it has high specificity and reproducibility in the assessment of vascular patients. In conclusion, when used correctly, the ABI remains a reliable and invaluable indicator of lower-limb perfusion and a useful tool for predicting the risk of future cardiovascular events. However, its underutilization in clinical settings is noteworthy.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"937-945"},"PeriodicalIF":2.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139097189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2025-11-01Epub Date: 2025-04-01DOI: 10.1177/00033197251333222
Bülent Özlek, Süleyman Barutçu, Veysel Ozan Tanık
{"title":"Letter: Emerging Biomarkers in the No-reflow Phenomenon: Unveiling the Inflammatory Connection.","authors":"Bülent Özlek, Süleyman Barutçu, Veysel Ozan Tanık","doi":"10.1177/00033197251333222","DOIUrl":"10.1177/00033197251333222","url":null,"abstract":"","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"1031-1032"},"PeriodicalIF":2.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}