IF 2.6 3区医学

Angiology Pub Date : 2024-11-01 Epub Date: 2023-10-23 DOI: 10.1177/00033197231210381

Theofanis Papas

引用次数: 0

Gender Modulated the Association of Sleep Apnea and Sleep Duration with Arterial Stiffness: The ELSA-Brasil Study. 性别调节睡眠呼吸暂停和睡眠时间与动脉僵硬度的关系：ELSA-巴西研究

IF 2.6 3区医学

Angiology Pub Date : 2024-11-01 Epub Date: 2023-09-09 DOI: 10.1177/00033197231193618

Lorenna F Cunha, Ronaldo B Santos, Soraya Giatti, Barbara K Parise, Aline N Aielo, Wagner A Silva, Silvana P Souza, Luiz A Bortolotto, Paulo A Lotufo, Isabela M Bensenor, Luciano F Drager

{"title":"Gender Modulated the Association of Sleep Apnea and Sleep Duration with Arterial Stiffness: The ELSA-Brasil Study.","authors":"Lorenna F Cunha, Ronaldo B Santos, Soraya Giatti, Barbara K Parise, Aline N Aielo, Wagner A Silva, Silvana P Souza, Luiz A Bortolotto, Paulo A Lotufo, Isabela M Bensenor, Luciano F Drager","doi":"10.1177/00033197231193618","DOIUrl":"10.1177/00033197231193618","url":null,"abstract":"Increased arterial stiffness is independently associated with cardiovascular risk. Obstructive sleep apnea (OSA) and sleep duration (SDUR) may contribute to increased arterial stiffness, but it is unclear whether this association is modulated by gender. We aimed to evaluate the potential impact of gender in modulating the association of OSA and SDUR with arterial stiffness. Participants from the ELSA-Brasil study performed sleep assessments with portable polygraph to define OSA severity and SDUR by 1-week wrist actigraphy. Pulse wave velocity (PWV) was measured using a standard technique without access to the sleep data. We studied 1863 participants (42.2% male, age: 49±8 years, respiratory disturbance index (RDI): 9.9 (4.5-19.4) events/h, SDUR: 6.5 (5.9-7.1) hours, mean PWV: 7.3 ± 1.2 m/s). We found that men had higher PWV, higher frequency of diabetes, and higher blood pressure when compared to women. The regression analysis showed an independent association between increased RDI and PWV in men (ß: 0.007; 95% CI: 0.001-0.012), but not in women. In contrast, an independent association between SDUR and increased arterial stiffness was observed only in women (ß: 0.068; 95% CI: 0.002-0.134). In conclusion, the association of sleep disorders with arterial stiffness showed a distinct gender pattern depending on the sleep variable studied.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10188177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Serum Bilirubin as a Novel Biomarker of Carotid Atherosclerosis. 血清胆红素作为颈动脉粥样硬化的新型生物标记物

IF 2.6 3区医学

Angiology Pub Date : 2024-11-01 Epub Date: 2023-09-11 DOI: 10.1177/00033197231202026

Yong-Hong Wang, Wei Pan

引用次数: 0

Carotid Stiffness After Transcatheter Aortic Valve Replacement. 经导管主动脉瓣置换术后的颈动脉僵硬度

IF 2.6 3区医学

Angiology Pub Date : 2024-11-01 Epub Date: 2023-08-12 DOI: 10.1177/00033197231195647

Refik Kavsur, Christian Schaefer, Max Jonathan Stumpf, Marcel Weber, Atsushi Sugiura, Marc Ulrich Becher, Sebastian Zimmer, Georg Nickenig, Nadjib Schahab

{"title":"Carotid Stiffness After Transcatheter Aortic Valve Replacement.","authors":"Refik Kavsur, Christian Schaefer, Max Jonathan Stumpf, Marcel Weber, Atsushi Sugiura, Marc Ulrich Becher, Sebastian Zimmer, Georg Nickenig, Nadjib Schahab","doi":"10.1177/00033197231195647","DOIUrl":"10.1177/00033197231195647","url":null,"abstract":"The present study aimed to analyze common carotid artery strain properties in patients (n = 59) with severe aortic valve stenosis who underwent transcatheter aortic valve replacement (TAVR). Arterial compliance of the common carotid artery was assessed by ultrasound speckle-tracking before and after TAVR. For sub-analysis the study cohort was divided according to aortic valve area <.75 cm2 (n = 30) vs ≥.75 cm2 (n = 29). Comparison of pre- and post-procedural strain variables showed an improvement in median radial velocity (P < .0001), radial displacement (P = .007), circumferential strain (P = .004), radial strain rate (P = .023), and circumferential strain rate (P < .0001), while the increase of radial strain showed a trend (P = .082). Analysis of aortic valve area revealed an inverse correlation between aortic valve area and the differences (post-procedural-pre-procedural values) for radial strain rate, and circumferential strain. Moreover, sub-analysis revealed that the increase of carotid strain variables before and after TAVR were more pronounced in the sub-group of aortic valve area .75 vs ≥.75 cm2. TAVR led to a reduction of arterial wall stiffness of the common carotid artery assessed by ultrasound speckle-tracking. The decrease of arterial wall stiffness after TAVR was more pronounced in more severe aortic valve stenosis.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9980034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Machine Learning and Omics Analysis in Aortic Aneurysm. 主动脉瘤的机器学习和Omics分析。

IF 2.6 3区医学

Angiology Pub Date : 2024-11-01 Epub Date: 2023-10-10 DOI: 10.1177/00033197231206427

Fabien Lareyre, Arindam Chaudhuri, Bahaa Nasr, Juliette Raffort

引用次数: 0

It Is Too Early to Consider Serum Bilirubin as a Definitive Novel Biomarker for Carotid Atherosclerosis. 现在认为血清胆红素是颈动脉粥样硬化的一种确定的新生物标志物还为时过早。

IF 2.6 3区医学

Angiology Pub Date : 2024-11-01 Epub Date: 2023-10-16 DOI: 10.1177/00033197231208747

Lu Qin, Haoyuan Wang, Wanru Zhou, Hebo Wang

引用次数: 0

The Association Between Arterial Stiffness and White Blood Cell Count: Missing Pieces of the Puzzle. 动脉僵化与白细胞计数之间的关系：拼图中缺失的部分。

IF 2.6 3区医学

Angiology Pub Date : 2024-11-01 Epub Date: 2023-09-06 DOI: 10.1177/00033197231201920

Yusuf Ziya Şener, Ömer Faruk Yilmaz

引用次数: 0

Immune-Checkpoint Inhibitor-Related Myocarditis: Where We Are and Where We Will Go. 免疫检查点抑制剂相关心肌炎：我们的现状与未来

IF 2.6 3区医学

Angiology Pub Date : 2024-11-01 Epub Date: 2023-09-12 DOI: 10.1177/00033197231201929

Andrea Vergara, Marco De Felice, Arturo Cesaro, Felice Gragnano, Ivana Pariggiano, Enrica Golia, Antonio De Pasquale, Ettore Blasi, Fabio Fimiani, Emanuele Monda, Giuseppe Limongelli, Paolo Calabrò

{"title":"Immune-Checkpoint Inhibitor-Related Myocarditis: Where We Are and Where We Will Go.","authors":"Andrea Vergara, Marco De Felice, Arturo Cesaro, Felice Gragnano, Ivana Pariggiano, Enrica Golia, Antonio De Pasquale, Ettore Blasi, Fabio Fimiani, Emanuele Monda, Giuseppe Limongelli, Paolo Calabrò","doi":"10.1177/00033197231201929","DOIUrl":"10.1177/00033197231201929","url":null,"abstract":"Immune checkpoint inhibitors (ICIs) are specific monoclonal antibodies directed against inhibitory targets of the immune system, mainly represented by programmed death-1 (PD1) ligand-1 (PD-L1) and cytotoxic T-lymphocyte antigen-4 (CTLA-4), thus enabling an amplified T-cell-mediated immune response against cancer cells. These drugs have significantly improved prognosis in patients with advanced metastatic cancer (e.g., melanoma, non-small cell lung cancer, renal cell carcinoma). However, uncontrolled activation of anti-tumor T-cells could trigger an excessive immune response, possibly responsible for multi-organ damage, including, among others, lymphocytic myocarditis. The incidence of ICIs-induced myocarditis is underestimated and the patients affected are poorly characterized. The diagnosis and management of this condition are mainly based on expert opinion and case reports. EKG and ultrasound are tests that can help identify patients at risk of myocarditis during treatment by red flags, such as QRS complex enlargement and narrowing of global longitudinal strain (GLS). Therapy of ICI-related myocarditis is based on immunosuppressors, monoclonal antibodies and fusion proteins. A future strategy could involve the use of microRNAs. This review considers the current state of the art of immune-related adverse cardiovascular events, focusing on histological and clinical features, diagnosis and management, including current treatments and future pharmacological targets.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10214265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence and clinical significance of deep vein thrombosis in Hispanic patients with acute pulmonary embolism. 西班牙裔急性肺栓塞患者深静脉血栓形成的发病率和临床意义。

IF 2.6 3区医学

Angiology Pub Date : 2024-11-01 Epub Date: 2023-08-04 DOI: 10.1177/00033197231194234

Adrian Rojas Murguia, Swathi Prakash, Fernando Segovia, Fatih Ayvali, Michael Brockman, Sahithi Nadella, Vishwajeet Singh, Alok Kumar Dwivedi, Manu Rajachandran, Debabrata Mukherjee, Nils P Nickel

{"title":"Prevalence and clinical significance of deep vein thrombosis in Hispanic patients with acute pulmonary embolism.","authors":"Adrian Rojas Murguia, Swathi Prakash, Fernando Segovia, Fatih Ayvali, Michael Brockman, Sahithi Nadella, Vishwajeet Singh, Alok Kumar Dwivedi, Manu Rajachandran, Debabrata Mukherjee, Nils P Nickel","doi":"10.1177/00033197231194234","DOIUrl":"10.1177/00033197231194234","url":null,"abstract":"The prevalence of concomitant deep vein thrombosis (DVT) and its impact on 30-day outcomes in Hispanic patients with acute pulmonary embolism (PE) is unknown. We retrospectively studied a cohort of Hispanic patients admitted for acute PE to determine the relationship of concomitant DVT to clot burden on chest computer tomography (CT), right heart strain, and 30-day mortality. We identified 391 patients admitted with acute PE; 168 (42.9%) had concomitant DVTs on admission; 39 patients (9.9%) died during the 30-day follow-up: 12 patients without concomitant DVT and 27 with concomitant DVT, respectively (p < .001). The presence of a proximal DVT independently predicted 30-day mortality even after adjusting for age, gender and admission PE severity index scores (PESI) (hazard ratio [HR] 2.0; 95% confidence interval [CI]: 1.4-3.0, p = .001). Proximal DVTs remained a significant predictor of 30-day mortality in patients with low and intermediate PESI scores (HR 2.5; 95% CI: 1.1-6.0, p = .035). The prevalence of concomitant DVT in Hispanic patients presenting with acute DVT is relatively lower than other ethnic groups. However, a proximal location of a DVT is of significant prognostic relevance. Hispanic patients with acute PE should routinely undergo compression doppler ultrasonography (CDUS) of the lower extremities.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9940374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fluoroquinolone Use Preceding Visceral Artery Dissection: A Case Series. 氟喹诺酮类药物在内脏动脉切开术前的应用：一个病例系列。

IF 2.6 3区医学

Angiology Pub Date : 2024-11-01 Epub Date: 2023-10-19 DOI: 10.1177/00033197231207945

Louise Z Wang, Boris Oehmichen, Benjamin Pariente, Nassim Mohamedi, Charles Cheng, Grégoire Detriche, Alexandre Galloula, Agnès Lilo Le Louet, Emmanuel Messas, Laurence Amar, Guillaume Goudot, Tristan Mirault

{"title":"Fluoroquinolone Use Preceding Visceral Artery Dissection: A Case Series.","authors":"Louise Z Wang, Boris Oehmichen, Benjamin Pariente, Nassim Mohamedi, Charles Cheng, Grégoire Detriche, Alexandre Galloula, Agnès Lilo Le Louet, Emmanuel Messas, Laurence Amar, Guillaume Goudot, Tristan Mirault","doi":"10.1177/00033197231207945","DOIUrl":"10.1177/00033197231207945","url":null,"abstract":"Fluoroquinolones (FQ), commonly prescribed antibiotics, may trigger aortic and carotid dissections. We report three successive cases of visceral artery dissection: one patient with celiac trunk dissection and two with dissection of the superior mesenteric artery. These events occurred up to 4 months after 7 to 14 days of FQ treatment (2 cases of ofloxacin, 1 of norfloxacin). There was no other apparent cause of dissection. These dissections were isolated, apart from a minimal aortic dissection separate from the visceral arterial dissection in one case. A case series cannot certify the relationship between dissection and FQ, but it can be hypothesized. The association between fluoroquinolone use and higher occurrence of aneurysm and dissection remains discussed in aortic syndrome. The potential link between FQ and visceral artery dissection is even less described but should be reported in the absence of previous cases in the literature. The pathophysiological theory is the induction of overexpression of some matrix metalloproteinases and a decrease of their inhibitors, provoking a dysregulation in collagen synthesis and degradation of the extracellular matrix.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49673738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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