IF 2.2 3区医学

Angiology Pub Date : 2026-05-07 DOI: 10.1177/00033197261448369

George Koudounas, Odysseas Lomvardeas, Thomas E Kalogirou, Konstantinos G Moulakakis, Konstantinos O Papazoglou, Christos D Karkos

{"title":"A Systematic Review of the Prognostic Value of Inflammatory Biomarkers in Outcomes After Endovascular Abdominal Aortic Aneurysm Repair.","authors":"George Koudounas, Odysseas Lomvardeas, Thomas E Kalogirou, Konstantinos G Moulakakis, Konstantinos O Papazoglou, Christos D Karkos","doi":"10.1177/00033197261448369","DOIUrl":"https://doi.org/10.1177/00033197261448369","url":null,"abstract":"The present review aimed to evaluate the prognostic value of inflammatory biomarkers in patients undergoing endovascular aortic aneurysm repair (EVAR). A systematic review of relevant studies was performed according to PRISMA guidelines. Articles assessing associations of inflammatory biomarkers with the post-EVAR outcomes were considered. After screening, 34 studies were included (7019 patients were reviewed; mean age: 73.6 years; 91.6% were men); 22 different inflammatory biomarkers were identified among the included studies. Neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and lymphocyte-to-monocyte ratio (LMR) were investigated in 11, 4, and 3 studies, respectively. Nine studies evaluated the post-implantation syndrome (PIS) and examined its role in post-EVAR outcomes. Increased preoperative NLR was associated with all-cause mortality and acute kidney injury after EVAR. NLR was also reported as an independent risk factor for aneurysm sac regression failure. High preoperative PLR and low preoperative LMR were correlated with acute kidney injury and overall mortality, respectively. PIS was associated with a lower type 2 endoleak rate but had no impact on mortality rates. NLR may be a useful predictor for mortality and poor prognosis in EVAR populations. This may have clinical implications in post-EVAR surveillance programs.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197261448369"},"PeriodicalIF":2.2,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147832941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inflammatory Prognostic Index May Predict the Development of Contrast-Induced Nephropathy in Patients with ST-Segment Elevation Myocardial Infarction. 炎症预后指数可预测st段抬高型心肌梗死患者造影剂肾病的发展。

IF 2.2 3区医学

Angiology Pub Date : 2026-05-07 DOI: 10.1177/00033197261447011

Yusuf Can, Emre Eynel, Şevval Özdemir, Sabri Çiftçi, Ahmet Telçeken, Ahmet Can Çakmak, Nimet Uçaroğlu Can, Direnç Yılmaz, Ömer Faruk Erkan, Fahrettin Turna, Havva Kocayiğit, İbrahim Kocayiğit

{"title":"Inflammatory Prognostic Index May Predict the Development of Contrast-Induced Nephropathy in Patients with ST-Segment Elevation Myocardial Infarction.","authors":"Yusuf Can, Emre Eynel, Şevval Özdemir, Sabri Çiftçi, Ahmet Telçeken, Ahmet Can Çakmak, Nimet Uçaroğlu Can, Direnç Yılmaz, Ömer Faruk Erkan, Fahrettin Turna, Havva Kocayiğit, İbrahim Kocayiğit","doi":"10.1177/00033197261447011","DOIUrl":"https://doi.org/10.1177/00033197261447011","url":null,"abstract":"Contrast-induced nephropathy (CIN) remains a frequent and clinically relevant complication in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (pPCI). This study evaluated the predictive performance of inflammation-based indices for CIN development, with a focus on the inflammatory prognostic index (IPI). STEMI patients (n = 563) were retrospectively analyzed. CIN developed in 85 patients (15.1%). Admission IPI values were significantly higher in patients who developed CIN compared with those without CIN (10.9 [7.6-16.2] vs 4.8 [3.1-7.9], P < .001). In multivariate logistic regression analysis, IPI remained independently associated with CIN (odds ratio [OR] 1.31, 95% confidence interval [CI] 1.06-1.61, P = .013), together with advanced age, higher blood urea nitrogen levels, reduced left ventricular ejection fraction, history of stroke, and the occurrence of no-reflow. Receiver operating characteristic analysis demonstrated superior discriminative performance for IPI (area under the curve [AUC] 0.826, 95% CI 0.783-0.869) compared with neutrophil-to-lymphocyte ratio (NLR; AUC 0.691), C-reactive protein-to-albumin ratio (CAR; AUC 0.712), and systemic immune inflammation index (SII; AUC 0.704). An admission IPI cutoff value of 8.35 predicted CIN with 82.4% sensitivity and 65.9% specificity. IPI demonstrates superior discriminative performance compared with CAR, NLR, and SII for predicting CIN in STEMI patients undergoing pPCI.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197261447011"},"PeriodicalIF":2.2,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147832875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Letter: Neutrophil Percentage-to-Albumin Ratio in Peripheral Arterial Disease: A Valuable Step, but Is a More Comprehensive Score Within Reach? 外周动脉疾病的中性粒细胞百分比与白蛋白比率：一个有价值的步骤，但是否可以实现更全面的评分？

IF 2.2 3区医学

Angiology Pub Date : 2026-05-07 DOI: 10.1177/00033197261448984

Samet Yavuz, Burak Bozkurt

引用次数: 0

Clinically Silent Multi-Territory Aneurysms in Cadavers: A Case Report and Literature Review. 尸体中临床无症状的多区域动脉瘤1例报告及文献复习。

IF 2.2 3区医学

Angiology Pub Date : 2026-05-07 DOI: 10.1177/00033197261448372

Nikita Mishra, Dawson Miller, Natasha Mohan, Chace Moncrief, Annabel Merritt, Clifford Moshay, Elie Flatow, Adi Pinkas

{"title":"Clinically Silent Multi-Territory Aneurysms in Cadavers: A Case Report and Literature Review.","authors":"Nikita Mishra, Dawson Miller, Natasha Mohan, Chace Moncrief, Annabel Merritt, Clifford Moshay, Elie Flatow, Adi Pinkas","doi":"10.1177/00033197261448372","DOIUrl":"https://doi.org/10.1177/00033197261448372","url":null,"abstract":"Aneurysms are permanent, focal dilations of vessels that are ≥150% of normal diameter. While single aneurysms are relatively common, the presence of multiple aneurysms in different vascular territories is uncommon, and consolidated discussions of such cases remain limited. We report the case of a 96-year-old male cadaver with extensive but clinically silent aortic aneurysms identified during routine anatomical dissection. A large abdominal tumor was also noted compressing the right renal artery. Additionally, we review published reports of multi-territory aneurysms, which highlight the heterogeneity in patients and presentation types, including genetic disorders that lead to aneurysmal disease. Rupture risk is multifactorial, influenced by size, morphology, multiplicity, growth rate, and thrombus burden. Multi-territory aneurysmal disease, though rare, represents a clinically significant entity that may remain undetected until rupture or incidental discovery. Four domains emerge as central to management: screening, risk factor modification, genetic considerations, and counseling. This cadaveric case illustrates the breadth of aneurysm presentations and reinforces the importance of broad screening strategies in their surveillance. It also highlights the roles of risk reduction, genetic evaluation, and patient-centered counseling in reducing morbidity and mortality from this often silent vascular pathology.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197261448372"},"PeriodicalIF":2.2,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147832891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Perfusion Index May be an Accurate Tool for Predicting the Progression of Ischemia in Patients with Peripheral Arterial Disease. 灌注指数可能是预测外周动脉疾病患者缺血进展的准确工具。

IF 2.2 3区医学

Angiology Pub Date : 2026-05-07 DOI: 10.1177/00033197261447018

Hiroyoshi Komai, Yuka Kitaoka, Nobuko Yamamoto, Islam Atta, Masato Ohno, Noriyuki Miyama, Noriyasu Morikage, Tadaaki Koyama

{"title":"The Perfusion Index May be an Accurate Tool for Predicting the Progression of Ischemia in Patients with Peripheral Arterial Disease.","authors":"Hiroyoshi Komai, Yuka Kitaoka, Nobuko Yamamoto, Islam Atta, Masato Ohno, Noriyuki Miyama, Noriyasu Morikage, Tadaaki Koyama","doi":"10.1177/00033197261447018","DOIUrl":"https://doi.org/10.1177/00033197261447018","url":null,"abstract":"To test the reliability of the perfusion index (PI), a new index of blood flow in the lower extremities, we studied 246 patients (368 legs) with ischemic foot symptoms between January 2020 and November 2024. The average PI (PIave) was measured with a saturation monitor probe applied to all toes. The PIave value was obtained within 5 minutes for each foot and decreased as the ischemia severity increased. Skin perfusion pressure was significantly positively correlated with PIave (r = .215; P < .001). Of the 201 limbs of conservatively treated patients, 12 of 74 limbs with a PIave < .27 progressed to chronic limb-threatening ischemia (CLTI), while only 2 of 127 limbs with a PIave ≥ .27 progressed (χ2 test; P < .001; negative predictive value: 98%). Logistic regression analysis revealed that PIave < .27 was significantly associated with disease progression. In conclusion, the PI is a simple and useful marker for accurately indicating the degree of ischemia in the toes. The PI can predict that a patient will not progress to CLTI in the next 3 months with conservative treatment and may contribute to safe follow-up.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197261447018"},"PeriodicalIF":2.2,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147832947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Beyond Unidirectional Injury: Bidirectional Interactions Between Arteriosclerosis and the Heart-Brain-Kidney Axis. 超越单向损伤：动脉硬化与心-脑-肾轴的双向相互作用。

IF 2.2 3区医学

Angiology Pub Date : 2026-05-07 DOI: 10.1177/00033197261448377

Feifan Hu, Yali Ge

引用次数: 0

Letter: Further Exploration of the Relationship Between Carotid Plaque Characteristics and High-Risk Coronary Artery Plaques in CAS Patients. CAS患者颈动脉斑块特征与高危冠状动脉斑块关系的进一步探讨

IF 2.2 3区医学

Angiology Pub Date : 2026-05-07 DOI: 10.1177/00033197261448979

Yuexin Zhang, Yahui Wei, Na Song, Xiaofeng Zhao, Ming Li, Li Xu

引用次数: 0

Sleep Deprivation, Endothelial Dysfunction and Hypertension: A Narrative Review. 睡眠剥夺、内皮功能障碍和高血压：一项叙述性综述。

IF 2.2 3区医学

Angiology Pub Date : 2026-05-06 DOI: 10.1177/00033197261447021

Dan Yang, Shuangliang Ma, Yu Yan

{"title":"Sleep Deprivation, Endothelial Dysfunction and Hypertension: A Narrative Review.","authors":"Dan Yang, Shuangliang Ma, Yu Yan","doi":"10.1177/00033197261447021","DOIUrl":"https://doi.org/10.1177/00033197261447021","url":null,"abstract":"This narrative review aims to elucidate the effects of sleep deprivation (SD) on vascular endothelial cells and blood pressure, synthesize the mechanistic pathways involved, and propose potential intervention strategies, thereby positioning SD as a treatable target in hypertension management. A comprehensive literature search was conducted using databases including PubMed, Web of Science, Embase, and Medline for studies published up to October 2025. Evidence was systematically reviewed to examine SD-induced endothelial dysfunction and its role in blood pressure regulation. Both acute SD (including single-night total sleep < 7 hours, extended wakefulness up to ~36 hours, or ≤5 consecutive nights of restricted sleep) and chronic SD (persistent sleep restriction > 1 week) could induce measurable endothelial impairment and sustained blood pressure elevation. Key mechanistic pathways identified included: (1) vasomotor imbalance, (2) sympathetic nervous system hyperactivation with impaired baroreflex sensitivity, (3) systemic inflammation, (4) oxidative stress, (5) metabolic disturbances, and (6) circadian misalignment affecting vascular clock genes. SD is a significant, modifiable risk factor for endothelial dysfunction and hypertension. These findings highlight the therapeutic potential of endothelial-focused approaches and SD intervention in sleep-compromised populations. Future research should prioritize elucidating the underlying mechanisms and developing valid, cost-effective interventions.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197261447021"},"PeriodicalIF":2.2,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147832929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Letter: Reconsidering the Incremental Prognostic Value of Hemoglobin in Patients With Acute Coronary Syndrome and Atrial Fibrillation. 信：重新考虑血红蛋白在急性冠状动脉综合征和心房颤动患者中的增量预后价值。

IF 2.2 3区医学

Angiology Pub Date : 2026-05-05 DOI: 10.1177/00033197261447331

Omer Dogan

引用次数: 0

Venous Thromboembolism in Pregnancy: Pathophysiology, Diagnostic Algorithms, and Therapeutic Approaches. 妊娠静脉血栓栓塞：病理生理学、诊断算法和治疗方法。

IF 2.2 3区医学

Angiology Pub Date : 2026-05-02 DOI: 10.1177/00033197261443810

Akhmetzhan Sugraliyev, Plinio Cirillo

{"title":"Venous Thromboembolism in Pregnancy: Pathophysiology, Diagnostic Algorithms, and Therapeutic Approaches.","authors":"Akhmetzhan Sugraliyev, Plinio Cirillo","doi":"10.1177/00033197261443810","DOIUrl":"https://doi.org/10.1177/00033197261443810","url":null,"abstract":"Venous thromboembolism (VTE), comprising deep venous thrombosis (DVT) and pulmonary embolism (PE), are frequently observed during pregnancy and may cause maternal death. During pregnancy, several physiological and anatomical changes occur that enhance thrombotic risk. In addition, this risk might be significantly increased by several patient-specific risk factors. Therefore, VTE risk assessment in all pregnant women is essential for early identification of those at increased risk so as to obtain a timely diagnosis and plan a correct therapeutic approach. Unfortunately, clinical examinations may be complicated by the overlap between common physiological symptoms of pregnancy and those indicative of VTE. Thus, validated clinical decision tools such as the LEFt (Left lower extremity (L), Edema (E) and, symptom onset during the First Trimester of pregnancy) rule for suspected DVT and the YEARS algorithm for suspected PE have been developed to aid diagnostic assessment. Definitive diagnosis of DVT or PE requires confirmation with appropriate imaging modalities. An early diagnosis is important to facilitate prompt initiation of therapy that has Low Molecular Weight Heparin as the cornerstone of prevention and treatment during pregnancy and the postpartum period. In this narrative review, we consider the major risk factors for VTE during pregnancy, key diagnostic algorithms and updated therapeutic approaches.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197261443810"},"PeriodicalIF":2.2,"publicationDate":"2026-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147810071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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