IF 2.6 3区医学

Angiology Pub Date : 2025-07-23 DOI: 10.1177/00033197251356577

Taylan Altiparmak, Hale Zeynep Batur Caglayan, Sevcihan Kesen Ozbek, Fatih Oncu, Atiye Cenay Karabork Kilic, Tugba Erdogan, Serife Yaymaci, Bijen Nazliel

{"title":"The Influence of Smoking and Systemic Inflammation on Carotid Artery Disease: A Cross-Sectional Analysis of Stenosis, Plaque Surface Characteristics.","authors":"Taylan Altiparmak, Hale Zeynep Batur Caglayan, Sevcihan Kesen Ozbek, Fatih Oncu, Atiye Cenay Karabork Kilic, Tugba Erdogan, Serife Yaymaci, Bijen Nazliel","doi":"10.1177/00033197251356577","DOIUrl":"https://doi.org/10.1177/00033197251356577","url":null,"abstract":"The role of inflammation in carotid plaque formation and instability has been highlighted in recent studies. We assessed the significance of smoking status on systemic inflammation and their relationships with carotid stenosis and carotid plaque surface characteristics. A total of 822 patients diagnosed with carotid artery stenosis were recruited and evaluated with systemic inflammation indices according to smoking status. Subgroups were balanced in terms of gender, age, and additional diseases. Systemic inflammation indices were found to be substantially higher in smokers (P < .001) and in patients with irregular-ulcerated surface plaques (P < .001). Plaque surfaces were more irregular and ulcerated in smokers (P < .001). No difference was detected between stenosis degree and smoking status or with systemic inflammation (P > .05). Pan-immune-inflammatory value (PIV) had a strong correlation with both smoking and plaque instability (P < .001, r = .771). Additionally, high PIV levels displayed a significant risk augmentation for irregular/ulcerated surface plaques (P < .001, Odds Ratio (OR):13.796; 95%CI, 5.647-33.701). These findings suggest that in patients with carotid atherosclerotic stenosis, systemic inflammatory markers especially PIV, alongside with plaque surface characteristics, may serve as valuable tools for evaluating and monitoring plaque inflammation. This may lead to more personalized and effective treatment strategies, particularly in smokers.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197251356577"},"PeriodicalIF":2.6,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144688786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endocan, a Potential Biomarker of Endothelial Dysfunction: A Brief Overview. 内啡肽，内皮功能障碍的潜在生物标志物：概述。

IF 2.6 3区医学

Angiology Pub Date : 2025-07-22 DOI: 10.1177/00033197251356576

Megha Bidlan, Mohit Kumar, Anurag Bhargava, Vrinda Goel, Vijay Kumar

{"title":"Endocan, a Potential Biomarker of Endothelial Dysfunction: A Brief Overview.","authors":"Megha Bidlan, Mohit Kumar, Anurag Bhargava, Vrinda Goel, Vijay Kumar","doi":"10.1177/00033197251356576","DOIUrl":"https://doi.org/10.1177/00033197251356576","url":null,"abstract":"Endocan (endothelial cell-specific molecule 1, ESM-1), is a proteoglycan produced by the vascular endothelium that modulates cellular functions such as adhesion, migration, and proliferation. Elevated serum endocan levels are associated with autoimmune and inflammatory disorders, acting as a marker of endothelial activation and dysfunction. This brief overview considers endocan's role in HTN, cirrhosis, diabetes, peripheral arterial disease (PAD), coronavirus Disease 2019 (COVID-19), erectile dysfunction (ED), and psoriasis vulgaris. Data were gathered from research reporting endocan levels, illness markers, and clinical outcomes. Elevated endocan levels are associated with endothelial dysfunction, which contributes to diabetes complications and associated with vascular endothelial growth factor A (VEGF-A) activation. In HTN, endocan promotes inflammatory signaling and lymphocyte infiltration. In liver disease, particularly cirrhosis, elevated levels correlate with hepatic fibrosis and poor prognosis. PAD patients show raised endocan correlating with disease severity. COVID-19 studies suggest coronavirus induces endotheliitis. In ED, higher endocan levels are linked with endothelial dysfunction and impaired vascular reactivity, serving as a potential biomarker for vascular-related ED. In psoriasis vulgaris, endocan levels correlate with disease severity and cardiovascular risk. The present brief overview supports that monitoring endocan levels may improve treatment and prognosis. Further research is required to define its clinical potential.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197251356576"},"PeriodicalIF":2.6,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144688784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Letter: Association Between Anemia and Prognosis in Patients With Acute Coronary Syndrome and Atrial Fibrillation. 信函：急性冠状动脉综合征和心房颤动患者贫血与预后的关系。

IF 2.6 3区医学

Angiology Pub Date : 2025-07-22 DOI: 10.1177/00033197251360684

Hilal Tunçer, Özden Seçkin, Serkan Ünlü

引用次数: 0

Latent Class Analysis Identifies Distinct Patient Phenotypes Associated With Mistaken Treatment Decisions and Adverse Outcomes in Coronary Artery Disease. 潜在类分析确定与冠状动脉疾病错误治疗决策和不良结局相关的不同患者表型。

IF 2.6 3区医学

Angiology Pub Date : 2025-07-19 DOI: 10.1177/00033197251350182

Jing Qi, Zhiqiang Wang, Xiaoteng Ma, Zhijian Wang, Yueping Li, Lixia Yang, Dongmei Shi, Yujie Zhou

{"title":"Latent Class Analysis Identifies Distinct Patient Phenotypes Associated With Mistaken Treatment Decisions and Adverse Outcomes in Coronary Artery Disease.","authors":"Jing Qi, Zhiqiang Wang, Xiaoteng Ma, Zhijian Wang, Yueping Li, Lixia Yang, Dongmei Shi, Yujie Zhou","doi":"10.1177/00033197251350182","DOIUrl":"https://doi.org/10.1177/00033197251350182","url":null,"abstract":"This study aimed to identify patient characteristics linked to mistaken treatments and major adverse cardiovascular events (MACE) in percutaneous coronary intervention (PCI) for coronary artery disease (CAD) using deep learning-based fractional flow reserve (DEEPVESSEL-FFR, DVFFR). A retrospective cohort of 3,840 PCI patients was analyzed using latent class analysis (LCA) based on eight factors. Mistaken treatment was defined as negative DVFFR patients undergoing revascularization or positive DVFFR patients not receiving it. MACE included all-cause mortality, rehospitalization for unstable angina, and non-fatal myocardial infarction. Patients were classified into comorbidities (Class 1), smoking-drinking (Class 2), and relatively healthy (Class 3) groups. Mistaken treatment was highest in Class 2 (15.4% vs. 6.7%, P < .001), while MACE was highest in Class 1 (7.0% vs. 4.8%, P < .001). Adjusted analyses showed increased mistaken treatment risk in Class 1 (OR 1.96; 95% CI 1.49-2.57) and Class 2 (OR 1.69; 95% CI 1.28-2.25) compared with Class 3. Class 1 also had higher MACE risk (HR 1.53; 95% CI 1.10-2.12). In conclusion, comorbidities and smoking-drinking classes had higher mistaken treatment and MACE risks compared with the relatively healthy class.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197251350182"},"PeriodicalIF":2.6,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144666950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Letter: Is AISI a Reliable Predictor of Prognosis in Patients With CAD and CKD? 信函：AISI是CAD和CKD患者预后的可靠预测因子吗？

IF 2.6 3区医学

Angiology Pub Date : 2025-07-18 DOI: 10.1177/00033197251359696

Jian-Yong Wang, Ai-Min Li, Na Gao

引用次数: 0

Letter: Role of AISI in Prognosis of CAD With CKD: An Inflammatory Perspective. 信：AISI在CAD合并CKD的预后中的作用：一个炎症的角度。

IF 2.6 3区医学

Angiology Pub Date : 2025-07-14 DOI: 10.1177/00033197251359695

Nuo Li, De-Gang Mo

引用次数: 0

Connexin 43 and Atypical Chemokine Receptor 3 in Peripheral Blood Mononuclear Cells of Patients With Aneurysmal Subarachnoid Hemorrhage. 动脉瘤性蛛网膜下腔出血患者外周血单个核细胞中的连接蛋白43和非典型趋化因子受体3。

IF 2.6 3区医学

Angiology Pub Date : 2025-07-07 DOI: 10.1177/00033197251350186

Jian Yan, DianDa Chen, JinLin Xiao, XuYe Wu, ErMing Zeng, Tao Hong, Jian Duan

引用次数: 0

Letter: Comment on Cap et al., 2025: A Promising Coronary Flow Assessment Tool; However, Gaps Remain. 信：评论Cap等人，2025：一个有前途的冠状动脉血流评估工具；然而，差距依然存在。

IF 2.6 3区医学

Angiology Pub Date : 2025-07-06 DOI: 10.1177/00033197251356582

Aykut Demirkıran, Cihan Aydın, Hüseyin Orta

引用次数: 0

C-Reactive Protein-Albumin-Lymphocyte (CALLY) Index and Length of Hospital Stay in Patients With Heart Failure. 心衰患者c -反应蛋白-白蛋白淋巴细胞（CALLY）指数与住院时间的关系

IF 2.6 3区医学

Angiology Pub Date : 2025-07-05 DOI: 10.1177/00033197251355348

Cihan Aydın, Aykut Demirkıran, Hüseyin Orta

引用次数: 0

Impact of Low Bone Mineral Content Index on Cardiovascular Outcomes in Patients With Coronary Artery Disease Undergoing Percutaneous Coronary Intervention. 低骨矿物质含量指数对接受经皮冠状动脉介入治疗的冠心病患者心血管预后的影响

IF 2.6 3区医学

Angiology Pub Date : 2025-07-01 Epub Date: 2024-01-04 DOI: 10.1177/00033197231226348

Tadashi Itagaki, Yasushi Ueki, Daisuke Sunohara, Moeko Aoki, Fumika Nomoto, Toshifumi Takamatsu, Tomoaki Mochidome, Takashi Miura, Toshio Kasai, Koichiro Kuwahara, Uichi Ikeda

{"title":"Impact of Low Bone Mineral Content Index on Cardiovascular Outcomes in Patients With Coronary Artery Disease Undergoing Percutaneous Coronary Intervention.","authors":"Tadashi Itagaki, Yasushi Ueki, Daisuke Sunohara, Moeko Aoki, Fumika Nomoto, Toshifumi Takamatsu, Tomoaki Mochidome, Takashi Miura, Toshio Kasai, Koichiro Kuwahara, Uichi Ikeda","doi":"10.1177/00033197231226348","DOIUrl":"10.1177/00033197231226348","url":null,"abstract":"The prognostic value of bone mineral content (BMC) for the clinical outcomes of patients with coronary artery disease (CAD) remains unknown. The present study evaluated the association between BMC index (BMCI) and cardiovascular events between January 2020 to June 2021, in consecutive patients (n = 257) with CAD undergoing percutaneous coronary intervention (PCI) at the Nagano Municipal Hospital. BMCI was measured using bioelectrical impedance analysis and calculated as the BMC divided by height squared. Patients were classified as low (<0.918) or high BMCI (≥0.918) groups according to the receiver operating characteristics curve analysis for the primary endpoint, major adverse cardiovascular events (MACE), including cardiovascular death, spontaneous myocardial infarction, stroke, and any revascularization. During a median follow-up of 744 days, the low BMCI group (n = 152) had an increased risk of MACE compared with the high group (n = 105) (19.7 vs 6.7%, P = .004). A low BMCI was significantly associated with MACE in the multivariable Cox and the Inverse Probability of Treatment Weighting analyses (hazard ratio: 3.16, 95% confidence interval: 1.15-8.67, P = .025). In conclusion, among patients with CAD undergoing PCI, BMCI was a predictor for cardiovascular events. Further research is required to determine whether medical interventions for BMC can improve patient prognosis.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"580-588"},"PeriodicalIF":2.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139085655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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