AngiologyPub Date : 2025-10-01Epub Date: 2023-02-08DOI: 10.1177/00033197231155225
Rebecca N Treffalls, Kelly Poe, Hossam Abdou, David P Stonko, Joseph Edwards, Randall R DeMartino, Thomas Ptak, Jonathan J Morrison
{"title":"Exploring Intra-arterial Contrast Administration for Intraoperative Imaging Using a Swine Model.","authors":"Rebecca N Treffalls, Kelly Poe, Hossam Abdou, David P Stonko, Joseph Edwards, Randall R DeMartino, Thomas Ptak, Jonathan J Morrison","doi":"10.1177/00033197231155225","DOIUrl":"10.1177/00033197231155225","url":null,"abstract":"<p><p>Intraoperative computed tomography (CT) imaging with endovascular delivery of intra-arterial (IA) contrast could potentially provide higher attenuation with lower contrast volumes than intravenous (IV) administration. We aimed to compare IA and IV contrast use for organ-specific CT abdominal imaging. Five anesthetized swine had external jugular and brachial artery access with ascending aortic pigtail placement. An IV protocol was 100 mL at 5 mL/sec over 20 sec <i>vs</i> 50 mL of IA contrast at 5 mL/sec over 10 sec. Region-of-interest markers were applied to anatomical regions to measure attenuation (HU) over time. IA and IV contrast protocols achieved adequate aortic opacification (IA, 455 ± 289 <i>vs</i> IV, 450 ± 114 HU). The IA contrast aortic attenuation curve reached peak attenuation compared with IV contrast (IA, 8 vs 23 sec; P < .001). Time to peak attenuation was similar between IA and IV contrast in the portal vein (IA, 38 <i>vs</i> IV, 42 sec, <i>P</i> = .25). IA administration achieved a superior contrast-to-noise ratio (CNR) in less time compared with IV (R<sup>2</sup> = .94; <i>P</i> < .001). IA contrast achieved adequate opacification with less bolus broadening and a superior CNR compared with IV contrast while using a smaller contrast volume for directed organ-directed imaging.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"833-840"},"PeriodicalIF":2.2,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10733095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2025-10-01Epub Date: 2024-03-15DOI: 10.1177/00033197241238512
Tao He, Behnood Mohammadpour, Matthew Willman, Shirin Yaghoobpoor, Jonathan Willman, Brandon Lucke-Wold, Sarina Aminizadeh, Shokoufeh Khanzadeh, Aida Bazrgar, Arshin Ghaedi
{"title":"Prognostic Role of Neutrophil to Lymphocyte Ratio in Contrast-Induced Nephropathy: A Systematic Review and Meta-analysis.","authors":"Tao He, Behnood Mohammadpour, Matthew Willman, Shirin Yaghoobpoor, Jonathan Willman, Brandon Lucke-Wold, Sarina Aminizadeh, Shokoufeh Khanzadeh, Aida Bazrgar, Arshin Ghaedi","doi":"10.1177/00033197241238512","DOIUrl":"10.1177/00033197241238512","url":null,"abstract":"<p><p>This meta-analysis assessed the use of the neutrophil-to-lymphocyte ratio (NLR) as a means of early detection of contrast-induced nephropathy (CIN) following diagnostic or therapeutic procedures. We used Web of Science, PubMed, and Scopus to conduct a systematic search. There was no limitation regarding language or date of publication. We reported standardized mean difference (SMD) with a 95% confidence interval (CI). Due to high heterogeneity, a random-effects model was used, and the Newcastle-Ottawa scale was used for quality assessment. Thirty-one articles were included in the analysis. Patients in the CIN group had elevated levels of NLR compared with those in the non-CIN group (SMD = 0.78, 95% CI = 0.52-1.04, <i>P</i> < .001). Similar results were observed in either prospective (SMD = 1.03, 95% CI = 0.13-1.93, <i>P</i> = .02) or retrospective studies (SMD = 0.70, 95% CI = 0.45-0.96, <i>P</i> < .001). The pooled sensitivity of NLR was 74.02% (95% CI = 66.54%-81.02%), and the pooled specificity was 60.58% (95% CI = 53.94%-66.84%). NLR shows potential as a cost-effective biomarker for predicting CIN associated with contrast-involved treatments. This could help implement timely interventions to mitigate CIN and improve outcomes.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"819-832"},"PeriodicalIF":2.2,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140130601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2025-10-01Epub Date: 2024-07-19DOI: 10.1177/00033197241264956
Mustafa Oguz, Tayyar Akbulut, Faysal Saylik, Abdulcabbar Sipal, Emrah Erdal
{"title":"Response to Comments on the Association of Coronary Artery Severity and Late In-Stent Restenosis: An Angiographic Imaging Study.","authors":"Mustafa Oguz, Tayyar Akbulut, Faysal Saylik, Abdulcabbar Sipal, Emrah Erdal","doi":"10.1177/00033197241264956","DOIUrl":"10.1177/00033197241264956","url":null,"abstract":"","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"911-912"},"PeriodicalIF":2.2,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141726809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2025-09-29DOI: 10.1177/00033197251376082
Arzu Akgül, Çağatay Tunca, Alperen Taş, Mehmet Deniz Aylı
{"title":"Association of Serum Uric Acid and CRP/Albumin Ratio With Contrast-Induced Nephropathy in Acute Myocardial Infarction Patients.","authors":"Arzu Akgül, Çağatay Tunca, Alperen Taş, Mehmet Deniz Aylı","doi":"10.1177/00033197251376082","DOIUrl":"https://doi.org/10.1177/00033197251376082","url":null,"abstract":"<p><p>Contrast-induced nephropathy (CIN) significantly increases morbidity and mortality among acute myocardial infarction (MI) patients undergoing coronary angiography (CAG). This study evaluated the predictive value of serum uric acid (SUA) and C-reactive protein/albumin ratio (CAR) for CIN development. A retrospective analysis included 1326 acute MI patients who underwent CAG between November 2022 and January 2024. CIN occurred in 119 patients (9.0%). Higher SUA (5.60 vs 4.60 mg/dL, <i>P</i> < .001) and CAR (2.79 vs 2.15, <i>P</i> = .004) were significantly associated with CIN. Multivariate analysis confirmed SUA (Odds Ratio [OR]: 1.577, <i>P</i> < .001) and contrast volume (OR: 1.014, <i>P</i> < .001) as independent predictors. Receiver Operating Characteristic (ROC) analysis identified optimal SUA cutoff at 4.9 mg/dL (sensitivity 67.7%, specificity 68.1%). The predictive value of SUA was stronger among diabetic patients. Additionally, SUA positively correlated with CAR (<i>r</i> = .41, <i>P</i> < .001). A simplified risk score incorporating SUA, CAR, contrast volume, diabetes, and age effectively stratified CIN risk. Elevated SUA levels and high CAR independently predict CIN in acute MI patients, enhancing clinical risk stratification and guiding preventive strategies.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197251376082"},"PeriodicalIF":2.2,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145184560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2025-09-28DOI: 10.1177/00033197251382430
Song Peng Ang, Jia Ee Chia, Chayakrit Krittanawong, Debabrata Mukherjee
{"title":"Reply to Letter on 'Racial Differences in the Trends, Clinical Characteristics and Outcomes of Patients Undergoing Coronary Atherectomy'.","authors":"Song Peng Ang, Jia Ee Chia, Chayakrit Krittanawong, Debabrata Mukherjee","doi":"10.1177/00033197251382430","DOIUrl":"https://doi.org/10.1177/00033197251382430","url":null,"abstract":"","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197251382430"},"PeriodicalIF":2.2,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145184600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2025-09-24DOI: 10.1177/00033197251366696
Johannes Holm, Viktor Eriksson Lippe, Peter M Nilsson, Benjamin Nilsson Wadström
{"title":"Physical Activity, Arterial Stiffness, and Risk of Cardiovascular Disease and Death in Men and Women: A Population-Based Study.","authors":"Johannes Holm, Viktor Eriksson Lippe, Peter M Nilsson, Benjamin Nilsson Wadström","doi":"10.1177/00033197251366696","DOIUrl":"https://doi.org/10.1177/00033197251366696","url":null,"abstract":"<p><p>Physical activity lowers risk of cardiovascular disease and may also decrease arterial stiffness. We aimed to investigate whether arterial stiffness can explain part of the association between physical activity and the risk of major adverse cardiovascular events (MACE) and all-cause death in men and women. We followed 2583 individuals from the Malmö Diet and Cancer study (2007-2012) for occurrence of MACE in Swedish nationwide registries (mean follow-up: 9 years). Physical activity was self-assessed using a questionnaire. Arterial stiffness was assessed by carotid-femoral pulse wave velocity (cfPWV), the gold standard. Survival analyses were performed using Cox regression. In all individuals, multivariable adjusted hazard ratios per 1 m/s higher PWV were 1.09 (95% confidence interval: 1.05-1.14) for MACE and 1.06 (1.03-1.09) for death. Explained risk estimates for the association from physical activity through arterial stiffness were 12% (0%-100%) for risk of MACE and 5% (1%-16%) for risk of death; in men, corresponding results were 7% (0.4%-28%) and 7% (0%-51%). For women, physical activity was not associated with risk of MACE or death. In conclusion, arterial stiffness may explain part of the association from physical activity to risk of death and potentially risk of MACE in men.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197251366696"},"PeriodicalIF":2.2,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145129765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2025-09-24DOI: 10.1177/00033197251368948
Jia-Lin Zhou, Bao-Sheng Sun, Tai Li
{"title":"Serum Creatinine/Cystatin C as a Novel Biomarker of Atherosclerosis in Patients With Type 2 Diabetes Mellitus.","authors":"Jia-Lin Zhou, Bao-Sheng Sun, Tai Li","doi":"10.1177/00033197251368948","DOIUrl":"https://doi.org/10.1177/00033197251368948","url":null,"abstract":"","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197251368948"},"PeriodicalIF":2.2,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145129821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2025-09-23DOI: 10.1177/00033197251370103
Çağatay Tunca, Fatih Cihat Büyükbaş, Alperen Taş, Veysel Ozan Tanık, Süleyman Barutçu, Bülent Özlek
{"title":"The Osaka Prognostic Score Predicts All-Cause in-Hospital Mortality in Patients With Non-ST-Elevation Myocardial Infarction Undergoing Early Percutaneous Coronary Intervention.","authors":"Çağatay Tunca, Fatih Cihat Büyükbaş, Alperen Taş, Veysel Ozan Tanık, Süleyman Barutçu, Bülent Özlek","doi":"10.1177/00033197251370103","DOIUrl":"https://doi.org/10.1177/00033197251370103","url":null,"abstract":"<p><p>The Osaka Prognostic Score (OPS) is a composite index reflecting systemic inflammation and nutritional status, derived from C-reactive protein, albumin, and lymphocyte count. This retrospective study evaluated the association between OPS and all-cause in-hospital mortality in 959 patients with non-ST-elevation myocardial infarction (NSTEMI) undergoing early percutaneous coronary intervention from September 2022 to November 2024. Patients were stratified into 4 groups based on OPS (0-3), with all-cause in-hospital mortality as the primary endpoint. Cox proportional hazards modeling was used to identify independent predictors of mortality, and receiver operating characteristic analysis assessed the prognostic performance of OPS. During hospitalization (maximum 12 days), 106 patients (11.0%) died. Non-survivors were significantly older (69.1 vs 58.9 years, <i>P</i> < .001) and more frequently female (36.8 vs 19%, <i>P</i> < .001). Independent predictors included advanced age, low diastolic blood pressure, higher Killip class, reduced left ventricular ejection fraction, elevated creatinine and troponin levels, and high OPS values (hazard ratio: 3.032; 95% confidence interval [CI]: 2.003-4.102; <i>P</i> < .001). An OPS threshold of 1.5 yielded 94% sensitivity and 74% specificity (95% CI: 0.859-0.937; <i>P</i> < .001), with mortality rates of 3.7%, 4.2%, 17.1%, and 59.1% across OPS categories (<i>P</i> < .001). Incorporating OPS with conventional risk factors may enhance the risk stratification of NSTEMI.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197251370103"},"PeriodicalIF":2.2,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145129819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2025-09-23DOI: 10.1177/00033197251378551
Ting Liu, Shiwen Zhang, Xin Zou, Ye Wang, Jinsheng Zhang, Shaojing Shi, Zixuan Zhao, Yiran Zhao, Bernhard Kolberg, Jing Li
{"title":"Letter: \"Relationship Between Total Cholesterol/High-Density Lipoprotein Cholesterol and Carotid Artery Plaque in Ischemic Stroke Patients Based on Sex and Age\".","authors":"Ting Liu, Shiwen Zhang, Xin Zou, Ye Wang, Jinsheng Zhang, Shaojing Shi, Zixuan Zhao, Yiran Zhao, Bernhard Kolberg, Jing Li","doi":"10.1177/00033197251378551","DOIUrl":"https://doi.org/10.1177/00033197251378551","url":null,"abstract":"","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197251378551"},"PeriodicalIF":2.2,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145129862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative Outcomes of Stress Echocardiography and CT Coronary Angiography in the Assessment of Suspected Coronary Artery Disease: A Pilot Study.","authors":"Ayesha Ashfaq, Harmeet Chana, Abdul-Majeed Salmasi","doi":"10.1177/00033197251376087","DOIUrl":"https://doi.org/10.1177/00033197251376087","url":null,"abstract":"<p><p>Stress echocardiography (SE) detects myocardial ischemia while coronary computed tomography angiography (CCTA) detects structural abnormalities associated with coronary artery disease (CAD). A pilot retrospective study of 270 consecutive patients who underwent both SE and CCTA to explore which test is more accurate in patients with CAD. Health records and risk factors, SE, and CCTA outcomes were reviewed. SE outcomes were positive (n = 36) and negative (n = 234); CCTA outcomes were based on CAD severity (absent, mild, moderate, and severe). 219 (81.1%) patients had a positive CCTA, indicating the presence of CAD with mild, moderate, or severe stenosis. Despite a positive CCTA (n = 191), 70.7% had a negative SE. This discrepancy was most prevalent in the moderate CCTA category, where 110 patients had a negative SE but positive CCTA. Additionally, 9 patients demonstrated a positive SE despite no significant CCTA findings, indicating that functional abnormalities could have remained undetected by anatomical imaging. It is suggested that significant CAD detected by CCTA does not necessarily suggest myocardial ischemia, while the presence of myocardial ischemia is not necessarily associated with significant CAD, suggesting other causes (e.g., microvascular angina). A positive CCTA but negative SE findings may suggest the presence of coronary collaterals.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197251376087"},"PeriodicalIF":2.2,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145129848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}