Angiology最新文献_第2页

No Causal Association Between Inguinal Hernia and Aortic Aneurysm Using Mendelian Randomization Analysis. 通过孟德尔随机分析，腹股沟疝与主动脉瘤之间没有因果关系

IF 2.6 3区医学

Angiology Pub Date : 2025-07-01 Epub Date: 2024-01-04 DOI: 10.1177/00033197241226509

Sicheng Yao, Hongbo Ci

{"title":"No Causal Association Between Inguinal Hernia and Aortic Aneurysm Using Mendelian Randomization Analysis.","authors":"Sicheng Yao, Hongbo Ci","doi":"10.1177/00033197241226509","DOIUrl":"10.1177/00033197241226509","url":null,"abstract":"Aortic aneurysm (AA) is a serious disease that affects the aging population worldwide. Potential risk or associated factors, such as inguinal hernia, have been suggested by conventional studies. In the present study, summary statistics data for the associations of inguinal hernia were derived from a large genome-wide association study including 18,791 inguinal hernia cases and 93,955 controls in the UK Biobank. Corresponding data of AA were extracted from FinnGen, comprising 7603 cases and 317,899 controls in Finland. The causal association was assessed using Mendelian Randomization-Egger, weighted median, and inverse variance weighting methods, and compared with observational estimates previously published. Our analysis found no convincing causal effect between genetically predicted inguinal hernia and the risk of AA (odds ratio [OR] = 1.05, 95% confidence interval [CI] = 0.85-1.31, P = .65), abdominal aortic aneurysm (AAA, OR = 1.15, 95% CI = 0.92-1.46, P = .22), and thoracic aortic aneurysm (TAA, OR = 1.05, 95% CI = 0.85-1.30, P = .67). The results are in contrast to previous observational evidence suggesting a potentially common causal association between inguinal hernia and AA. Further research is needed to better understand the interplay between risk factors and their impact on aneurysm development.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"525-530"},"PeriodicalIF":2.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139097191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Imbalance Between Angiotensin II and Kallikrein in Patients With ST-Segment Elevation Myocardial Infarction: A Case-Control Emergency Room Study. ST 段抬高型心肌梗死患者血管紧张素 II 与 Kallikrein 之间的失衡：急诊室病例对照研究》。

IF 2.6 3区医学

Angiology Pub Date : 2025-07-01 Epub Date: 2024-02-05 DOI: 10.1177/00033197241232165

Shuhong Dai, Bo Yin, Haiming Wang, Xiaowei Zhang

{"title":"Imbalance Between Angiotensin II and Kallikrein in Patients With ST-Segment Elevation Myocardial Infarction: A Case-Control Emergency Room Study.","authors":"Shuhong Dai, Bo Yin, Haiming Wang, Xiaowei Zhang","doi":"10.1177/00033197241232165","DOIUrl":"10.1177/00033197241232165","url":null,"abstract":"The present study aimed to investigate the balance between angiotensin II (Ang-II) and kallikrein (KLK1) in the pathogenesis of ST-segment elevation acute myocardial infarction (STEMI). The study included a total of 261 participants: 151 STEMI patients and 110 individuals with normal coronary arteries. The plasma levels of Ang-II and KLK1 were measured using enzyme-linked immunosorbent assays (ELISA). Multivariate logistic regression analysis indicated that the plasma levels of Ang-II, KLK1 and the ratio of Ang-II and KLK1 (Ang-II/KLK1) independently correlated with the presence of STEMI. Furthermore, we found independent associations between STEMI and smoking, cholesterol (CHO), high-density lipoprotein cholesterol (HDL-c), as well as age. The ratio of Ang-II/KLK1 correlated with the plasma level of the inflammatory cytokine, interleukin-6 (IL-6). Both Ang-II and KLK1 levels are significantly elevated in patients with STEMI. An increased Ang-II/KLK1 ratio may result in the over-activation of Ang-II and exacerbate the progression of STEMI(P = .046). In conclusion, we have demonstrated, for the first time, an Ang-II and KLK1 imbalance in patients with STEMI.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"589-596"},"PeriodicalIF":2.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139691076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Gender on Triple Heart Valve Surgery Outcomes; Reinforcing Women's Health. 性别对三联心脏瓣膜手术结果的影响；加强妇女健康。

IF 2.6 3区医学

Angiology Pub Date : 2025-07-01 Epub Date: 2024-01-07 DOI: 10.1177/00033197241226863

Fatimah A Alhijab, Huda Ismail, Monirah Albabtain, Juan Alfonso, Khaled D Algarni, Claudio Pragliola, Adam I Adam, Amr A Arafat

{"title":"The Effect of Gender on Triple Heart Valve Surgery Outcomes; Reinforcing Women's Health.","authors":"Fatimah A Alhijab, Huda Ismail, Monirah Albabtain, Juan Alfonso, Khaled D Algarni, Claudio Pragliola, Adam I Adam, Amr A Arafat","doi":"10.1177/00033197241226863","DOIUrl":"10.1177/00033197241226863","url":null,"abstract":"Female gender is a risk factor in several cardiac surgery risk stratification systems. This study explored the differences in the outcomes following triple heart valve surgery in men vs women. The study included 250 patients (males n = 101; females n = 149) who underwent triple valve surgery from 2009 to 2020. BMI (body mass index) was higher in females (29.6 vs 26.5 kg/m2, P < .001), and diabetes was more common in males (44 vs 42%, P = .012). The ejection fraction was higher in females (55 vs 50%, P < .001). The severity of mitral valve stenosis and tricuspid valve regurgitation was significantly greater in females (33.11 vs 27.72%, P = .003 and 44.30 vs 19.8%, P < .001, respectively). Mitral valve replacement was more common in females (P < .001), and they had lower concomitant coronary artery bypass grafting (P = .001). Bleeding and renal failure were lower in females (P = .021 and <0.001, respectively). Hospital mortality, readmission, and reintervention were not significantly different between genders. By multivariable analysis, male gender was a risk factor for lower survival [HR (hazard ratio): 2.18; P = .024]. Triple valve surgery can be performed safely in both genders, with better long-term survival in females. Female gender was not a risk factor in patients undergoing triple valve surgery.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"554-562"},"PeriodicalIF":2.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139377140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Increased Cardio-ankle Vascular Index Values in Migraine Patients With Aura. 有先兆的偏头痛患者心踝关节血管指数值升高。

IF 2.6 3区医学

Angiology Pub Date : 2025-07-01 Epub Date: 2024-01-18 DOI: 10.1177/00033197241228043

Yusuf Can, Nimet Uçaroğlu Can, Çağla Akçay, Sena Boncuk Ulaş, Ibrahim Kocayiğit, Havva Kocayiğit, Mustafa Tarık Ağaç

{"title":"Increased Cardio-ankle Vascular Index Values in Migraine Patients With Aura.","authors":"Yusuf Can, Nimet Uçaroğlu Can, Çağla Akçay, Sena Boncuk Ulaş, Ibrahim Kocayiğit, Havva Kocayiğit, Mustafa Tarık Ağaç","doi":"10.1177/00033197241228043","DOIUrl":"10.1177/00033197241228043","url":null,"abstract":"Patients with migraine with aura are at an increased risk of cardiovascular disease. There are limited data on arterial stiffness in migraine patients with aura. The present study evaluated arterial stiffness in these patients using the cardio-ankle vascular index (CAVI). This prospective study included 50 patients with migraine with aura (43 female, mean age 38.9 ± 9.9 years). The patient group was matched for age and gender with 50 healthy individuals with no history of migraine (43 female, mean age 39.3 ± 10.3 years). All patients and control subjects underwent a comprehensive clinical evaluation by an experienced neurologist and were interviewed about their headache histories. There was no significant difference in baseline demographic characteristics and echocardiographic parameters between migraine with aura patients and the control group. Both right and left CAVI values were significantly higher in the patients with migraine with aura (6.5 ± 1.2 vs 6.1 ± 0.7, P = .043 and 6.6 ± 1.2 vs 6.1 ± 0.7, P = .009, respectively). Arterial stiffness is an important mediator of cardiovascular diseases. We found that CAVI, a novel marker of the arterial stiffness, is increased in patients with migraine with aura.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"531-537"},"PeriodicalIF":2.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139484989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aortic Stiffness Can be Predicted From Different eGFR Formulas With Long Follow-Up in the Malmö Diet Cancer Study. 在马尔默饮食癌症研究的长期随访中，可通过不同的 eGFR 公式预测主动脉僵硬度。

IF 2.6 3区医学

Angiology Pub Date : 2025-07-01 Epub Date: 2024-02-09 DOI: 10.1177/00033197241232719

Anders Christensson, Simon Lundgren, Madeleine Johansson, Peter M Nilsson, Gunnar Engström, Agne Laucyte-Cibulskiene

{"title":"Aortic Stiffness Can be Predicted From Different eGFR Formulas With Long Follow-Up in the Malmö Diet Cancer Study.","authors":"Anders Christensson, Simon Lundgren, Madeleine Johansson, Peter M Nilsson, Gunnar Engström, Agne Laucyte-Cibulskiene","doi":"10.1177/00033197241232719","DOIUrl":"10.1177/00033197241232719","url":null,"abstract":"We studied the impact of estimated glomerular filtration rate (eGFR) based on either creatinine or cystatin C, or in combination, on vascular aging (aortic stiffness) and central hemodynamics (central systolic blood pressure) in a Swedish urban population with median 17 years of follow-up. Participants (n = 5049) from the population-based Malmö Diet and Cancer Study that underwent baseline examination and later participated in the prospective cardiovascular arm were selected. Of these, 2064 with measured carotid-femoral pulse wave velocity (cfPWV) and central blood pressure at follow-up were enrolled. eGFR was calculated using cystatin C (eGFRCYS) and creatinine (eGFRCR) equations: Caucasian, Asian, pediatric, and adult cohorts (CAPA), the Lund-Malmö revised (LMrev), and the European Kidney Function Consortium (EKFC) equations. Lower adjusted eGFRCR, but not eGFRCYS, were independently associated with higher cfPWV (P < .001, respectively). eGFR <60 mL/min/1.73 m2 determined higher cfPWV except when using the EKFC equation. Conversely, CAPA/LMrev and CAPA/EKFC ratios were not associated with aortic stiffness. Lower eGFRCR is associated with higher future aortic stiffness independently of age, sex, heart rate, mean blood pressure, body mass index, and antihypertensive treatment. The ratio of eGFRCYS and eGFRCR equations could not predict aortic stiffness at all.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"563-571"},"PeriodicalIF":2.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12222838/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139705940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Triglyceride-Glucose Index as a Novel Biomarker for Major Adverse Cardiovascular Events. 甘油三酯-葡萄糖指数作为重大不良心血管事件的新型生物标记物

IF 2.6 3区医学

Angiology Pub Date : 2025-07-01 Epub Date: 2024-01-31 DOI: 10.1177/00033197241231150

Xin Zhang, Yong Yang, Yun-Shan Jiang

引用次数: 0

Prevalence, Characteristics, and Outcomes of Infective Endocarditis Readmissions in Patients With Variables Associated With Liver Disease in the United States. 美国肝病相关变量患者感染性心内膜炎再入院的患病率、特征和结果。

IF 2.6 3区医学

Angiology Pub Date : 2025-07-01 Epub Date: 2024-01-12 DOI: 10.1177/00033197241227502

Mohamed Khayata, Richard A Grimm, Brian P Griffin, Bo Xu

{"title":"Prevalence, Characteristics, and Outcomes of Infective Endocarditis Readmissions in Patients With Variables Associated With Liver Disease in the United States.","authors":"Mohamed Khayata, Richard A Grimm, Brian P Griffin, Bo Xu","doi":"10.1177/00033197241227502","DOIUrl":"10.1177/00033197241227502","url":null,"abstract":"Infective endocarditis (IE) is common in patients with liver disease. Outcomes of IE in patients with liver disease are limited. We aimed to investigate IE outcomes in patients with variables associated with liver disease in the USA. We used the 2017 National Readmission Database to identify index admission of adults with IE, based on the International Classification of Disease, 10th revision codes. The primary outcome was 30-day readmission. Secondary outcomes were mortality and predictors of hospital readmission. We identified 40,413 IE admissions. Patients who were readmitted were more likely to have a history of HCV (19.4 vs 12.3%, P < .001), hyponatremia (25 vs 21%, P < .001), and thrombocytopenia (20.3 vs 16.3%, P < .001). After adjusting for age, hypertension, heart failure, diabetes mellitus, and end stage renal disease, hyponatremia (odds ratio (OR) 1.25; 95% confidence intervals [CI]: 1.17-1.35; P < .001) and thrombocytopenia (OR 1.16; 95% CI: 1.08-1.24; P < .001) correlated with higher odds of 30-day readmission. Mortality was higher among patients with hyponatremia (29 vs 22%, P < .001), thrombocytopenia (29 vs 17%, P < .001), coagulopathy (12 vs 5%, P < .001), cirrhosis (6 vs 4%, P < .001), ascites (7 vs 3%, P < .001), liver failure (18 vs 3%, P < .001), and portal hypertension (3 vs 1.5%, P < .001).","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"538-545"},"PeriodicalIF":2.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139432230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Systemic Immune-Inflammation Index and Predicting Cardiac Implantable Electronic Device Infections: Reply. 全身免疫炎症指数与心脏植入式电子设备感染的预测：回复。

IF 2.6 3区医学

Angiology Pub Date : 2025-07-01 Epub Date: 2024-05-28 DOI: 10.1177/00033197241257548

Banu Karaca, Fatma Kayaaltı Esin

引用次数: 0

Letter: Relationship Between Magnesium Levels and Contrast Nephropathy in Patients with ST-Elevation Myocardial Infarction. 信：st段抬高型心肌梗死患者镁水平与造影剂肾病的关系。

IF 2.6 3区医学

Angiology Pub Date : 2025-07-01 Epub Date: 2025-03-04 DOI: 10.1177/00033197251326385

Cihan Aydın, Hüseyin Orta, Mesut Engin, Aykut Demirkıran

引用次数: 0

Letter: Systemic Immune-Inflammation Index and Cardiac Implantable Electronic Device Infections. 信：全身免疫炎症指数与心脏植入式电子设备感染