AngiologyPub Date : 2025-03-01Epub Date: 2023-11-04DOI: 10.1177/00033197231213197
Ya Qin, Xiao Liang, Hongshuai Wu, Xia Sun, Shuai Yan, Nanyao Wang, Ming Yuan, Qiong Wang, Dan Wu
{"title":"Development and Validation of a Modified Khorana Score for Predicting Venous Thromboembolism in Newly Diagnosed Stage IV Lung Cancer.","authors":"Ya Qin, Xiao Liang, Hongshuai Wu, Xia Sun, Shuai Yan, Nanyao Wang, Ming Yuan, Qiong Wang, Dan Wu","doi":"10.1177/00033197231213197","DOIUrl":"10.1177/00033197231213197","url":null,"abstract":"<p><p>We aimed to establish an effective model to identify metastatic lung cancer patients at high risk of venous thromboembolism (VTE). Patients diagnosed with stage IV lung cancer from January 2011 to June 2019 were included in the development cohort; those recruited from July 2019 to June 2021 were included in the validation cohort. Univariable and multivariable analyses determined the risk factors for VTE. Then we assessed the value for predicting VTE of the Khorana score and modified Khorana score in these two cohorts; 575 patients were included in the development cohort, and 202 patients in the validation cohort. Adenocarcinoma, D-dimer, and the Khorana score were independent risk factors for VTE. In the development cohort, the area under the receiver operating characteristic curve (AUC) of the Khorana score in patients with newly diagnosed stage IV lung cancer was 0.598 (95% CI, 0.512-0.684). The AUC of the modified Khorana score was 0.747 (95% CI, 0.689-0.805). The difference was statistically significant (<i>P</i> <.001). The AUC of the modified Khorana score in the validation cohort was 0.763 (95% CI, 0.661-0.865). The modified Khorana score is more able to accurately predict VTE in patients with newly diagnosed stage IV lung cancer than the Khorana score.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"264-270"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71477382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2025-03-01Epub Date: 2024-03-06DOI: 10.1177/00033197241238513
Kenan Toprak, Mustafa Kaplangoray, Mehmet Inanır, Ayten Dursun, Mustafa Begenc Tascanov, Ibrahim Halil Altıparmak, Asuman Biçer, Recep Demirbag
{"title":"Reply to Letter: HbA1c/C-Peptide Ratio is a Potential Biomarker Used to Predict No-Reflow Phenomenon in Patients With ST-Elevation Myocardial Infarction.","authors":"Kenan Toprak, Mustafa Kaplangoray, Mehmet Inanır, Ayten Dursun, Mustafa Begenc Tascanov, Ibrahim Halil Altıparmak, Asuman Biçer, Recep Demirbag","doi":"10.1177/00033197241238513","DOIUrl":"10.1177/00033197241238513","url":null,"abstract":"","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"302-303"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140038664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2025-03-01Epub Date: 2023-11-23DOI: 10.1177/00033197231218331
Panagiotis Theofilis, Panayotis K Vlachakis, Emmanouil Mantzouranis, Athanasios Sakalidis, Christina Chrysohoou, Ioannis Leontsinis, George Lazaros, Kyriakos Dimitriadis, Maria Drakopoulou, Aikaterini Vordoni, Evangelos Oikonomou, Konstantinos Tsioufis, Dimitris Tousoulis
{"title":"Acute Coronary Syndromes in Women: A Narrative Review of Sex-Specific Characteristics.","authors":"Panagiotis Theofilis, Panayotis K Vlachakis, Emmanouil Mantzouranis, Athanasios Sakalidis, Christina Chrysohoou, Ioannis Leontsinis, George Lazaros, Kyriakos Dimitriadis, Maria Drakopoulou, Aikaterini Vordoni, Evangelos Oikonomou, Konstantinos Tsioufis, Dimitris Tousoulis","doi":"10.1177/00033197231218331","DOIUrl":"10.1177/00033197231218331","url":null,"abstract":"<p><p>Acute coronary syndromes (ACSs) encompass a spectrum of life-threatening cardiovascular conditions, including unstable angina (UA) and myocardial infarction. While significant progress has been made in the understanding and management of ACS over the years, it has become increasingly evident that sex-based differences play a pivotal role in the pathophysiology, presentation, and outcomes of these conditions. Despite this recognition, the majority of clinical research in the field has historically focused on male populations, leading to a significant knowledge gap in understanding the unique aspects of ACS in women. This review article aims to comprehensively explore and synthesize the current body of literature concerning the sex-specific characteristics of ACS, shedding light on the epidemiology, risk factors, clinical presentation, diagnostic challenges, treatment strategies, and prognosis in women. By elucidating the distinct aspects of ACS in women, this review intends to foster greater awareness and improved clinical management, ultimately contributing to enhanced cardiovascular care for female patients.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"209-224"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138298154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2025-03-01Epub Date: 2023-11-03DOI: 10.1177/00033197231213166
Kenan Toprak, Mustafa Kaplangoray, Tolga Memioğlu, Mehmet İnanır, Bahadır Omar, Mehmet Fatih Ermiş, İbrahim Halil Toprak, Osman Acar, Mustafa Begenç Taşcanov, İbrahim Halil Altıparmak, Asuman Biçer, Recep Demirbağ
{"title":"The HbA1c/C-Peptide Ratio is Associated With the No-Reflow Phenomenon in Patients With ST-Elevation Myocardial Infarction.","authors":"Kenan Toprak, Mustafa Kaplangoray, Tolga Memioğlu, Mehmet İnanır, Bahadır Omar, Mehmet Fatih Ermiş, İbrahim Halil Toprak, Osman Acar, Mustafa Begenç Taşcanov, İbrahim Halil Altıparmak, Asuman Biçer, Recep Demirbağ","doi":"10.1177/00033197231213166","DOIUrl":"10.1177/00033197231213166","url":null,"abstract":"<p><p>Currently, the gold standard treatment for ST-elevation myocardial infarction (STEMI) is primary percutaneous coronary intervention (pPCI), but even after successful pPCI, a perfusion disorder in the epicardial coronary arteries, termed no-reflow phenomenon (NR), can develop, resulting in short- and long-term adverse events. The present study assessed the relationship between NR and HbA1c/C-peptide ratio (HCR) in 1834 consecutive patients who underwent pPCI due to STEMI. Participants were divided into two groups according to NR status and the demographic, clinical and periprocedural characteristics of the groups were compared. NR developed in 352 (19.1%) of the patients in the study. While C-peptide levels were significantly lower in the NR group, HbA1c and HCR were significantly higher (<i>P</i> < .001, for all). In multivariable analysis, C-peptide, HbA1c, and HCR, were determined as independent predictors for NR (<i>P</i> < .05, for all). In Receiver Operating Characteristic (ROC) analysis, HCR predicted the NR with 80% specificity and 77% sensitivity. In STEMI patients, combining HbA1c and C-peptide in a single fraction has a predictive value for NR independent of diabetes. This ratio may contribute to risk stratification of STEMI patients.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"289-299"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71420218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2025-03-01Epub Date: 2023-10-17DOI: 10.1177/00033197231206234
Abdullah Al-Kasasbeh, Ahmad Abdalmajeed Alghzawi, Mohamad Jarrah, Muhannad Ababneh, Hanna Al-Makhamreh, Joud Shehadeh, Afnan Migdadi, Mohammad Jum'ah, Anas Ahmad, Daria Ja'arah, Anwar Y Al Omary, Ayman Hammoudeh
{"title":"Clinical Profiles and One-Year Outcome in Middle Eastern Patients With Atrial Fibrillation and Hypertension: Analysis From the Jordan Atrial Fibrillation Study.","authors":"Abdullah Al-Kasasbeh, Ahmad Abdalmajeed Alghzawi, Mohamad Jarrah, Muhannad Ababneh, Hanna Al-Makhamreh, Joud Shehadeh, Afnan Migdadi, Mohammad Jum'ah, Anas Ahmad, Daria Ja'arah, Anwar Y Al Omary, Ayman Hammoudeh","doi":"10.1177/00033197231206234","DOIUrl":"10.1177/00033197231206234","url":null,"abstract":"<p><p>Studies on the impact of hypertension (HTN) on the outcome of patients with atrial fibrillation (AF) in the Middle East are scarce. The aim of this contemporary multicenter study is to evaluate the effect of the coexisting HTN on the baseline clinical profiles and 1-year prognosis in a cohort of Middle Eastern patients with AF. Consecutive AF patients in 29 hospitals and cardiology clinics were enrolled in the Jordan AF study (May 2019-December 2020). Patients were prospectively followed up for 1 year, and the study had no influence on their treatment, which was at the discretion of the treating physician. We compared clinical features, use of medications, and 1-year prognosis in patients with AF/HTN compared with AF/no HTN. Among 1849 non-valvular AF patients, 76.4% had HTN, with higher prevalence of diabetes, dyslipidemia, coronary heart disease, stroke, and left ventricular hypertrophy in HTN patients. There was a higher thromboembolic and bleeding risk among HTN patients. At 1 year, HTN patients had significantly higher rates of stroke and systemic embolism (SSE) (4.5%), acute coronary syndrome (ACS) (2.4%), rehospitalization (27.9%), and major bleeding events (3.0%) compared with non-HTN patients. In this cohort, the coexistence of HTN was associated with worse baseline clinical profile and 1-year outcomes.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"249-256"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41231981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2025-03-01Epub Date: 2023-12-26DOI: 10.1177/00033197231225294
De-Gang Mo, Meng-Meng Wang
{"title":"HbA1c/C-Peptide Ratio Is a Potential Biomarker Used to Predict No-Reflow Phenomenon in Patients With ST-Elevation Myocardial Infarction.","authors":"De-Gang Mo, Meng-Meng Wang","doi":"10.1177/00033197231225294","DOIUrl":"10.1177/00033197231225294","url":null,"abstract":"<p><p>In this letter, we discussed that HbA1c/C-peptide ratio is a potential biomarker used to predict no-reflow phenomenon in patients with ST-elevation myocardial infarction.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"300-301"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139039425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exploring the Associations Between Non-Traditional Lipid Parameters and Epicardial Adipose Tissue Volume.","authors":"Junli Ren, Guang Yao, Lichen Ren, Yiran Wang, Jianbo Gao, Yonggao Zhang","doi":"10.1177/00033197231207264","DOIUrl":"10.1177/00033197231207264","url":null,"abstract":"<p><p>The aim of this retrospective study was to determine the relationship between non-traditional lipid parameters and epicardial adipose tissue (EAT). A total of 770 patients with coronary computed tomography angiography examinations were included. The non-traditional lipid parameters included the atherogenic index of plasma (AIP), the atherogenic coefficient (AC), monocyte to high-density lipoprotein cholesterol (HDL-C) ratio (MHR), and lipoprotein combined index (LCI). To investigate the association between non-conventional lipid markers and the EAT-volume (EAT-v), a univariate and multivariate analyses were conducted. The receiver operating characteristic (ROC) analysis was used to compare the predictive ability among the four non-traditional lipid parameters. In the univariate analysis, we identified factors that might have effects on EAT-v (all <i>P</i><.05) and adjusted for these in the multivariate analysis. We found that except for MHR, other non-traditional lipid parameters were still associated with high EAT-v after adjustment (all <i>P</i><.05). In the ROC analysis, the area under the curve (AUC) of AIP was greater than that of other non-traditional lipid parameters and lipid profiles. There was an association between both non-traditional lipid parameters and EAT-v. After adjustment, the AIP remained an independent predictor of EAT-v and it outperformed other non-traditional lipid parameters.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"239-248"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41231982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2025-03-01Epub Date: 2024-01-05DOI: 10.1177/00033197231219836
Yifang Liu, Chao Wang, Pu Zhang, Wenning Fu, Jun Zhang, Zeyu Zhang, Jing Mao, Yang Yang, Li Zou
{"title":"Association Between the Frequency of Tooth Brushing and the Risk of Cardiovascular Disease: A Systematic Review and Meta-analysis.","authors":"Yifang Liu, Chao Wang, Pu Zhang, Wenning Fu, Jun Zhang, Zeyu Zhang, Jing Mao, Yang Yang, Li Zou","doi":"10.1177/00033197231219836","DOIUrl":"10.1177/00033197231219836","url":null,"abstract":"<p><p>Several epidemiological studies suggested that frequency of tooth brushing may be associated with cardiovascular disease (CVD) risk, but the results remain inconclusive. Therefore, the aim of this study was to synthesize frequency of tooth brushing and CVD risk using meta-analysis. Science Direct, PubMed, CINAHL, and OVID were searched through October 15, 2022. The random-effects model was used to quantitatively assess the combined risk estimation. In addition, we performed the sensitivity analysis to evaluate the robustness of the study results by excluding the included studies one by one. A total of 9 cohort studies containing 10 reports with 803,019 individuals were included in the meta-analysis. Pooled results showed that compared with the lowest brushing frequency, the highest brushing frequency (relative risk = 0.85, 95% confidence interval: 0.80-0.90) significantly reduced the risk of cardiovascular disease. There was moderate heterogeneity among included studies (<i>P</i> = .002, I<sup>2</sup> = 65.4%). The exclusion of any one study did not materially change the combined risk estimates. Our meta-analysis supported the hypothesis that higher frequency of tooth brushing can reduce the risk of CVD, which may have important implications for conducting research on the prevention strategies of CVD.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"225-234"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139097190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2025-03-01Epub Date: 2023-10-20DOI: 10.1177/00033197231209584
Fatih Sivri, Ismail Türköz, Mehtap Şencan, Yahya Kemal İçen, Fatih Aksoy, Banu Öztürk Ceyhan
{"title":"Does COVID-19 Cause Non-Dıpper Hypertension?","authors":"Fatih Sivri, Ismail Türköz, Mehtap Şencan, Yahya Kemal İçen, Fatih Aksoy, Banu Öztürk Ceyhan","doi":"10.1177/00033197231209584","DOIUrl":"10.1177/00033197231209584","url":null,"abstract":"<p><p>Coronavirus disease 2019 (COVID-19) remains a health problem worldwide. The present study aimed to investigate the effect of blood pressure (BP) on the circadian pattern and prevalence of new-onset non-dipper hypertension in the post-COVID period in patients with known hypertension. This prospective single-center study included 722 patients hospitalized for COVID-19 infection. Ambulatory BP (ABP) data were collected during their initial hospitalization. The ABP data were reassessed 1 month after the patients were discharged. The results were compared with a healthy control group with known hypertension but without COVID-19 infection. After exclusion criteria were applied, the study included 187 patients with COVID-19 and 136 healthy hypertensive controls. Post-COVID ABP showed that patients with COVID-19 had significantly higher mean 24-h systolic and diastolic BP, mean nighttime systolic and diastolic BP, and mean daytime diastolic BP than the control group. In addition, new-onset non-dipper hypertension was significantly higher in patients with COVID-19. This study demonstrated for the first time that the circadian pattern is disturbed and a non-dipper pattern develops in individuals with known hypertension during the post-COVID period.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"257-263"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49673737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AngiologyPub Date : 2025-03-01Epub Date: 2023-09-20DOI: 10.1177/00033197231203575
Maïmouna Sow, David Saadoun, Patrice Cacoub, Alexandre Le Joncour
{"title":"Screening for Lung Cancer by Chest Computed Tomography During Thromboangiitis Obliterans.","authors":"Maïmouna Sow, David Saadoun, Patrice Cacoub, Alexandre Le Joncour","doi":"10.1177/00033197231203575","DOIUrl":"10.1177/00033197231203575","url":null,"abstract":"<p><p>Buerger's disease or thromboangiitis obliterans (TAO) is a non-atherosclerotic inflammatory arteritis strongly associated with smoking exposure. This tobacco use would expose patients to lung cancer. The French-speaking thoracic cancer intergroup recommends screening for lung cancer with a chest computed tomography (CT). Our study aims to evaluate lung cancer screening using chest CT during TAO. Ninety-seven TAO patients were included. The mean age of onset of TAO symptoms was 36.5 ± 10 years, and 73 (75%) were male. The mean follow-up was 8.5 ± 14 years. Overall, at least one chest CT was performed during follow-up in 32 (33%) patients. Twenty-three of the thirty-four (68%) patients who were over 50 at follow-up did not have a CT. An abnormality was found in 15 of the 32 (47%) patients who had a CT: lung nodules 6/15, lung mass 1/15, emphysema 6/15, and others 2. Two cases of lung adenocarcinoma were diagnosed. None died during 2 years follow-up. In conclusion, two-third of the TAO patients over 50 years of age did not receive the routine screening recommended in the general smoking population. Two cases of lung cancer have been diagnosed. Improving screening practices for lung cancer in this high-risk population is crucial.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"235-238"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41112282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}