Annali italiani di chirurgia最新文献

{"title":"Electrochemotherapy for Cancers Affecting the Skin: Ten Years of Experience in a Tertiary Referral Hospital.","authors":"Piero Covarelli, Carlo Boselli, Francesco Barberini, Matteo Matteucci, Georgi Popivanov, Vincenzo De Giorgi, Gianmarco Tomassini, Mario Mandalà, Roberto Cirocchi","doi":"10.62713/aic.3718","DOIUrl":"https://doi.org/10.62713/aic.3718","url":null,"abstract":"<p><strong>Aim: </strong>Electrochemotherapy (ECT) combines chemotherapy with an electric pulse to directly target tumor cells by increasing cell membrane permeability, facilitating the efficient uptake of chemotherapeutic agents by tumor cells and improving their therapeutic efficacy. It is widely used for treating skin metastatic nodules or metastases of subcutaneous tissue. Therefore, the aim of this study is to report the experience regarding the use of ECT in a tertiary referral hospital and explore its safety and efficacy in treating skin cancer.</p><p><strong>Methods: </strong>This study included 97 skin cancer patients treated with ECT at the Surgical Oncological Unit of the University of Perugia, Italy, between 2013 and 2024. ECT was performed using the Cliniporator® device (model EP02, IGEA, Carpi, Italy). The individuals with life expectancy greater than three months and American Society of Anesthesiologists physical status classification of I-III were included in this study, while those with arrhythmia and allergies to bleomycin were excluded.</p><p><strong>Results: </strong>In this study, melanoma was the most frequently observed malignancy, accounting for 47.4% of all cases. A total of 46 melanoma patients aged between 42 and 93 years underwent ECT treatment. Most of these patients presented with in-transit metastases (67.4%) and often had multiple lesions (71.74%). Furthermore, 21 patients received only one session, while 25 underwent multiple sessions. Almost all procedures were performed with intravenous administration of bleomycin. However, in two cases, intralesional cisplatin was used for a recurrence of melanoma localized in the scalp. Notably, no adverse events were observed during ECT procedure. Moreover, most of the patients (70.45%) were alive one year after the first ECT session. The 5-year probability of survival was 24% after the first ECT session.</p><p><strong>Conclusions: </strong>Electrochemotherapy represents a safe and effective therapeutic strategy for various malignancies, with significant potential for future clinical applications.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 2","pages":"194-204"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143432358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Myocardial Infarction Due to Spontaneous Coronary Artery Dissection at 36 Weeks of Pregnancy: A Case Report.","authors":"Paolo Meloni, Paolo Izzo, Luciano Izzo, Manfredi Arioti, Terenzia Simari, Federico Ariel Sanchez, Cristian Cascione, Andrea Montevecchi, Chiara Boccherini, Fausta Orsi, Claudia De Intinis, Sara Izzo","doi":"10.62713/aic.3747","DOIUrl":"https://doi.org/10.62713/aic.3747","url":null,"abstract":"<p><strong>Aim: </strong>Acute myocardial infarction in pregnancy (pAMI) is a rare event that is often caused by non-classical factors rather than atherosclerosis. The management of such complications requires a multidisciplinary team, and it is important to bring together the specialties involved to ensure that these teams are coordinated and ready to respond. The management of pAMI poses unique challenges because it requires consideration of both maternal and fetal well-being.</p><p><strong>Case presentation: </strong>We present the case of a 36-week pregnant woman who presented with anterolateral ST elevation myocardial infarction (STEMI) complicated by cardiogenic shock. To ensure comprehensive decision making, an emergency Pregnancy Heart Team meeting was convened, which comprised interventional cardiologists, gynecologists, and anesthesiologists. The team prioritized interventional treatment for pAMI, according to European Society of Cardiology (ESC) guidelines, and opted for primary percutaneous coronary intervention (PCI) due to the unstable maternal condition.</p><p><strong>Results: </strong>The patient underwent primary PCI as the chosen intervention for pAMI. A rapid response gynecology team closely monitored the procedure and was prepared to intervene in case of irreversible hemodynamic compromise leading to cardiac arrest. An emergency cesarean section was deemed necessary if cardiac activity was not restored within 4 minutes.</p><p><strong>Conclusions: </strong>Managing pAMI requires a multidisciplinary approach that balances the maternal and fetal well-being. In this particular case, the Pregnancy Heart Team decided to prioritize interventional treatment with primary PCI due to the unstable maternal condition. The presence of a closely monitored gynecology team ensured prompt action in case of complications.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 3","pages":"309-314"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Association of the Cancer Inflammation Prognostic Index with Microsatellite Instability, Tumor Budding and Prognosis in Colorectal Adenocarcinoma.","authors":"Uğur Topal, Sercan Yüksel, Mehmet Zişan Songür, Rabia Doğukan, Erdal Karaköse, Zafer Teke, Hasan Bektaş","doi":"10.62713/aic.3858","DOIUrl":"https://doi.org/10.62713/aic.3858","url":null,"abstract":"<p><strong>Aim: </strong>This study aimed to investigate the relationship between the Cancer Inflammation Prognostic Index (CIPI) and microsatellite instability (MSI), tumor budding, and prognosis in colorectal cancer cases.</p><p><strong>Methods: </strong>Patients with stage 1-3 colorectal cancer who underwent curative surgical treatment between May 2020 and January 2022 were included. Serum CIPI was calculated, a cut-off point was established using Receiver Operating Characteristic (ROC) analysis and Patients were divided into two groups according to their CIPI scores: Group 1 (low CIPI) consisted of 94 patients, and Group 2 (high CIPI) consisted of 95 patients.</p><p><strong>Results: </strong>A CIPI score >8.54 predicted mortality with 82.2% sensitivity and 59.7% specificity (area under the curve (AUC): 0.712). There were differences in tumor localization (p = 0.01). Group 2 had higher C-reactive protein (CRP) levels (4.2 vs 11.7, p < 0.001), lower albumin levels (4.1 vs 4, p = 0.04), higher neutrophil counts (3.76 vs 4.83, p = 0.002), and higher levels of carcinoembryonic antigen (CEA) and carbohydrate antigen 19.9 (Ca 19.9) (2.08 vs 8.27, p < 0.001 and 8.85 vs 13.9, p = 0.014, respectively). Tumor diameter was larger in high CIPI group (3 vs 3.8 cm, p = 0.001) , disease-free survival (37.7 vs 27.6 months, p < 0.001) and overall survival (39.6 vs 30.6 months, p < 0.001) were lower in high CIPI group 2. In the multivariate Cox regression analysis, a high CIPI score remained a strong independent predictor of poor overall survival (hazard ratio (HR) = 3.383, 95% confidence interval (CI): 1.445-7.921, p = 0.005) disease-free survival, a high CIPI score again stood out as a critical prognostic factor (HR = 3.280, 95% CI: 1.695-6.347, p < 0.001).</p><p><strong>Conclusions: </strong>A high CIPI score is associated with poor histopathological features and decreased survival. Closer monitoring or more aggressive treatment might improve prognosis for patients with high CIPI values.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 3","pages":"362-370"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of Aorto-Duodenal Fistula: Case Series and Technical Notes.","authors":"Roberto Santoro, Laura Antolino, Debora Maruca, Vittorio Brizi, Manuela Brighi, Antonio Bovino, Armando Raso, Fabrizio Chegai, Emanuele Santoro, Antonio Lorido","doi":"10.62713/aic.3920","DOIUrl":"https://doi.org/10.62713/aic.3920","url":null,"abstract":"<p><p>Aorto-duodenal fistula (ADF) is a rare clinical condition characterized by abnormal communication between the 3rd or 4th portion of the duodenum and the aorta, typically associated with aneurysmal disease. The incidence of ADF is expected to increase, however, there remains a lack of consensus on the optimal approach for intestinal restoration. In this study, we present three cases of ADF and their respective treatments using three distinct surgical techniques. Initially, endovascular aortic repair was employed as a life-saving procedure, followed by elective open repair. The choice of surgical technique was determined based on the patients' overall health conditions and the specific characteristics of the duodenal defect. In all cases, an omental patch was utilized to separate the aortic plane from the intestinal staple lines, providing additional protection for the sutures. The importance of a multimodal treatment strategy cannot be overstated, given the complex interplay of vascular, intestinal, and septic factors involved in the treatment of ADF.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 1","pages":"1-6"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142999028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Fast-Track Surgery Based on Nutritional Support in the Rehabilitation of Patients Undergoing Radical Thyroidectomy and Lateral Lymphadenectomy: A Retrospective Analysis.","authors":"Cheng Chen, Xuemei Dong, Shoupeng Zhang, Jun Wu, Junling Zhu","doi":"10.62713/aic.3764","DOIUrl":"https://doi.org/10.62713/aic.3764","url":null,"abstract":"<p><strong>Aim: </strong>This study aims to investigate the impact of fast-track surgery (FTS), based on nutritional support, on postoperative rehabilitation and nutritional status in patients undergoing radical thyroidectomy and lateral lymphadenectomy.</p><p><strong>Methods: </strong>This retrospective study included 112 patients who underwent radical thyroid cancer surgery and lateral neck lymph node dissection at Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, between April 2021 and April 2023. Based on various nursing methods, patients were divided into two groups, with 58 patients included in the observation group (FTS care based on nutritional support), and 54 patients in the control group (routine perioperative care). Postoperative clinical indicators, nutritional status, Quality of Life, associated complications, and follow-up outcomes at 3 and 12 months were compared between the two groups.</p><p><strong>Results: </strong>Patients in the observation group showed significantly shorter meal times, hospital stays, and off-bed time compared to the control group (p < 0.05). After three months of intervention, the observation group had higher body weight, muscle mass, and body fat, and lower Nutritional Risk Screening (NRS) scores compared to the control group (p < 0.05). At the 12-month follow-up, the observation group had better nutritional status indicators than the control group (p < 0.05). Furthermore, the observation group exhibited higher Quality of Life scores (p < 0.001) and reduced incidence of delayed complications (p < 0.05). During the three-month follow-up, the observation group demonstrated higher Quality of Life Questionnaire Core 30 (QLQ-C30) score compared to the control group (p < 0.05). Additionally, the overall incidence of complications was significantly lower in the observation group (p < 0.05).</p><p><strong>Conclusions: </strong>FTS nursing based on nutritional support effectively promotes postoperative recovery, improves nutritional status, and enhances Quality of Life in patients following radical thyroidectomy and lateral lymphadenectomy, which is worthy of being widely popularized.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 1","pages":"29-39"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142999003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrieval of Entrapped Embolic Protection Device during Carotid Artery Stenting: A Case Report.","authors":"Gaoyang Fan, Wenyuan Ma, Chunhai Su, Lei Feng, Wenwen Guo","doi":"10.62713/aic.3501","DOIUrl":"https://doi.org/10.62713/aic.3501","url":null,"abstract":"<p><strong>Aim: </strong>This study aims to report a rare case of an embolization protection device (EPD) entrapment during Carotid Artery Stent (CAS) and to discuss the management strategy, including open surgery and concurrent carotid endarterectomy (CEA).</p><p><strong>Case presentation: </strong>A 71-year-old female presented with left limb weakness and unclear speech following CAS. Imaging revealed a new cerebral infarction and right internal carotid artery stenosis. The patient underwent endovascular retrieval of the entrapped EPD, which failed, leading to an emergency open surgical procedure.</p><p><strong>Results: </strong>The surgical approach involved a longitudinal incision along the anterior border of the right sternocleidomastoid muscle, followed by carotid artery exposure and temporal artery clamps application. The entrapped EPD and stent were successfully retrieved, and the thrombus was aspirated. Subsequent endarterectomy removed the stenotic plaque, and meticulous washing cleared the carotid arteries. Post-operative indocyanine green fluorescence angiography confirmed patency of the arteries, and the patient was discharged without new neurological symptoms after 11 days of hospitalization.</p><p><strong>Conclusions: </strong>This case underscores the challenges in managing EPD entrapment during CAS and the necessity for a swift transition to open surgical intervention when endovascular techniques fail. The concurrent performance of CEA in such cases offers a comprehensive treatment strategy, highlighting the importance of a multidisciplinary approach in complex vascular interventions.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 1","pages":"7-13"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142999051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Surgeon's Role in Preventing Anal Squamous Cell Carcinoma.","authors":"Anna Maffioli, Gloria Zaffaroni, Andrea Bondurri","doi":"10.62713/aic.3843","DOIUrl":"https://doi.org/10.62713/aic.3843","url":null,"abstract":"<p><p>No abstract present.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 2","pages":"124-126"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143432306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Outcomes of DAMIS Traction Table-Assisted Anterior Approach versus Posterolateral Approach on Total Hip Arthroplasty in the Treatment of Femoral Head Necrosis.","authors":"Mao-Sen Lu, Yan-Ping Zhang, Yong-Jie Jiao, Long Wang, Xin Meng, Jie Zhang, Min Du, Han-Zhen Hu, Jian-Wei Du, Chang-Feng Liu","doi":"10.62713/aic.3829","DOIUrl":"https://doi.org/10.62713/aic.3829","url":null,"abstract":"<p><strong>Aim: </strong>Femoral head necrosis often leads to hip joint dysfunction, which can be effectively treated with total hip arthroplasty (THA). This study compares the clinical outcomes of direct anterior minimally invasive surgery (DAMIS) traction table-assisted anterior approach and the traditional posterolateral approach (PLA) on THA for femoral head necrosis.</p><p><strong>Methods: </strong>A total of 150 patients with femoral head necrosis, admitted between September 2019 and May 2022, were included in this study. In this sample, 68 patients underwent THA via the PLA (control group), while the remaining 82 patients were treated with THA using the DAMIS traction table-assisted anterior approach (observation group). The surgical-related indicators, postoperative pain scores, Harris hip scores (HHS), and rates of complication incidence between the two groups were compared.</p><p><strong>Results: </strong>There were no significant differences in surgery time between the two groups (p = 0.054). The observation group had significantly less intraoperative blood loss (p = 0.018), shorter incision length (p = 0.001), and significantly shorter time elapsed to first out-of-bed activity (p = 0.016) and shorter hospital stay compared to the control group (p = 0.001). The postoperative pain scores in the observation group were significantly lower than in the control group (p = 0.001), and the HHS at 2 weeks and 4 weeks after surgery were significantly higher in the observation group (p < 0.05). The overall complication rate in the observation group was significantly lower than in the control group (p = 0.011).</p><p><strong>Conclusions: </strong>DAMIS traction table-assisted anterior approach for THA demonstrates clinical advantages in the treatment of femoral head necrosis, effectively accelerating postoperative recovery and reducing the occurrence of complications.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 2","pages":"160-167"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143432353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Study on the Efficacy and Safety of Emergency Surgery Versus Endoscopic Stent Placement Followed by Definitive Surgery in the Treatment of Colorectal Obstruction.","authors":"Zhekang Jin, Xihan Jin, Jiying Lu","doi":"10.62713/aic.3799","DOIUrl":"https://doi.org/10.62713/aic.3799","url":null,"abstract":"<p><strong>Aim: </strong>Tumor-induced acute intestinal obstruction is a severe complication that poses significant threats to patient life. Emergency surgery is a widely used treatment method, but this approach has certain limitations such as high mortality and complication rates. Developments in endoscopic and minimally invasive techniques have provoked interest in postoperative definitive resection or conservative treatment following colorectal stent placement. Hence, this study aims to explore the clinical efficacy and safety of endoscopic-guided, X-ray-assisted intestinal stent placement in colorectal cancer (CRC) with acute intestinal obstruction, and to provide clinicians with viable alternative treatment options to enhance patient care.</p><p><strong>Methods: </strong>This study included 69 CRC patients who received treatment at the Affiliated Jinhua Hospital, Zhejiang University School of Medicine, China, between August 2017 and August 2021. The control group (n = 38) underwent emergency laparotomy with one-stage resection and stoma formation, followed by a postoperative second-stage stoma closure every 3 to 6 months. Moreover, the experimental group (n = 31) underwent endoscopic stent placement followed by definitive surgery. The differences in various indicators were compared between groups. Additionally, the 1-year and 3-year overall survival (OS) rates and disease-free survival (DFS) rates were compared between groups.</p><p><strong>Results: </strong>Successful placement of intestinal stents was achieved in all 31 patients, with acute intestinal obstruction relief within 24 to 48 hours. In the experimental group, stent placement effectively relieved intestinal obstruction, and a postoperative radical colon surgery was performed after 7 to 10 days. The experimental group had significantly lower rates of postoperative ventilator time, reduced time to oral intake, and fewer complication than the control group (p < 0.05). However, no significant differences were observed between groups regarding operation time, intraoperative blood loss, 1-year and 3-year OS rates, and 1-year and 3-year DFS rates (p > 0.05).</p><p><strong>Conclusions: </strong>Compared to emergency surgery, combined endoscopic and X-ray-guided colonic stent placement is an effective and safer method for alleviating acute intestinal obstruction in colorectal cancer. This study provides valuable insights to clinicians in selecting treatment options.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 2","pages":"261-268"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143432354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of Risk Factors and Preventive Measures for Perioperative Incision Infection in Patients Receiving Rigid Internal Fixation of Maxillofacial Fractures.","authors":"Fengxing Xu, Fan Wang","doi":"10.62713/aic.3853","DOIUrl":"https://doi.org/10.62713/aic.3853","url":null,"abstract":"<p><strong>Aim: </strong>To analyze the risk factors for perioperative incision infection in patients undergoing rigid internal fixation for maxillofacial fractures and the prevention and control measures formulated to enhance the effect of surgical treatment.</p><p><strong>Methods: </strong>We retrospectively analyzed the medical records of 342 maxillofacial fracture patients who received rigid internal fixation treatment at the Department of Stomatological Surgery of The First People's Hospital of Yongkang (Yongkang First People's Hospital) from May 2018 to April 2023, and divided them into the uninfected group (n = 308) and the infected group (n = 34) according to their history of perioperative incision infections. Data from the subjects on age, type of fracture trauma and length of hospitalization were collected and analyzed. Multifactorial logistic regression analysis was employed to explore the risk factors for perioperative incision infections in these patients and to develop preventive measures for these risk factors.</p><p><strong>Results: </strong>The study found that the incidence of incision infections was 9.94% (34/342) in 342 patients. Multifactorial logistic regression analysis showed that the incidence of incision infections was significantly higher in patients with comorbid diabetes mellitus versus those without comorbid diabetes mellitus (odds ratio [OR] = 9.543, 95% confidence interval [CI]: 1.818-50.095, p = 0.008); patients undergoing surgery in summer versus those in other seasons (OR = 8.483, 95% CI: 1.476-48.744, p = 0.017); and malnourished patients versus those with good nutritional status (OR = 5.163, 95% CI: 1.016-26.231, p = 0.048). In addition, the analysis also revealed that incision size was also a risk factor for incision infections during the postoperative period (OR = 2.882, 95% CI: 1.567-5.304, p = 0.001), whereas a higher preoperative albumin level was a protective factor (OR = 0.755, 95% CI: 0.639-0.891, p = 0.001).</p><p><strong>Conclusions: </strong>A plethora of risk factors can lead to incision infection in patients with maxillofacial fracture during perioperative period. Therefore, preventive measures should be implemented in the hospitals to control these factors in order to reduce the occurrence of complications and enhance the effectiveness of surgical treatment.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 2","pages":"213-220"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143432328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}