Annali italiani di chirurgia最新文献

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Comparison of Efficacy and Safety of Endoscopic Breast-Conserving Surgery Versus Conventional Breast-Conserving Surgery in Elderly Patients With Breast Cancer: Insights From a Single-Center Retrospective Analysis. 老年乳腺癌患者内镜保乳手术与常规保乳手术的疗效和安全性比较:来自单中心回顾性分析的见解
IF 0.9 4区 医学
Annali italiani di chirurgia Pub Date : 2025-01-01 DOI: 10.62713/aic.3989
Wei Zhang, Jundan Wang, Yun Xiong, Ying Hong
{"title":"Comparison of Efficacy and Safety of Endoscopic Breast-Conserving Surgery Versus Conventional Breast-Conserving Surgery in Elderly Patients With Breast Cancer: Insights From a Single-Center Retrospective Analysis.","authors":"Wei Zhang, Jundan Wang, Yun Xiong, Ying Hong","doi":"10.62713/aic.3989","DOIUrl":"https://doi.org/10.62713/aic.3989","url":null,"abstract":"<p><strong>Aim: </strong>Breast-conserving surgery (BCS) has been increasingly favored by elderly breast cancer patients to preserve their quality of life. This study compares the efficacy and safety of endoscopic versus conventional BCS in elderly patients, focusing on operative and aesthetic outcomes.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 261 elderly breast cancer patients (age ≥70) treated from January 2020 to January 2022. Patients were divided into endoscopic (n = 126) and conventional (n = 135) BCS groups. Surgical observations, complications, immune cell changes, adipokine levels, and survival rates were evaluated. Statistical analyses were performed using SPSS software.</p><p><strong>Results: </strong>Compared to the conventional BCS group, the endoscopic BCS group had significantly lower intraoperative blood loss (12.82 vs. 128.29 mL; p < 0.001), reduced hospitalization costs (13,289.74 vs. 16,032.41 Yuan; 1 Chinese Yuan ≈ 0.1385 US Dollars, p < 0.001), and shorter drainage duration (p = 0.002). The endoscopic BCS group reported superior aesthetic outcomes (66.67% rated as excellent vs. 50.37%; p = 0.047) and fewer surgical complications compared to the conventional BCS group, including lower rates of axillary pain, numbness, and arm swelling (p = 0.002, p = 0.002, and p = 0.008, respectively). No significant differences were observed in perioperative immune cell markers, adipokine levels, or survival outcomes between the groups.</p><p><strong>Conclusions: </strong>Endoscopic BCS offers advantages in reducing operative morbidity and enhancing aesthetic outcomes without compromising oncological safety for elderly patients.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 6","pages":"759-770"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of the Short-Term Quality of Life Changes of Patients Undergoing Orthognathic Surgery With Clear Aligners and Fixed Appliances: A Retrospective Study. 正面矫正器与固定矫治器行正颌手术患者短期生活质量变化的回顾性比较。
IF 0.9 4区 医学
Annali italiani di chirurgia Pub Date : 2025-01-01 DOI: 10.62713/aic.4083
Hong Gu, Guifeng Li, Hui Zhang
{"title":"Comparison of the Short-Term Quality of Life Changes of Patients Undergoing Orthognathic Surgery With Clear Aligners and Fixed Appliances: A Retrospective Study.","authors":"Hong Gu, Guifeng Li, Hui Zhang","doi":"10.62713/aic.4083","DOIUrl":"https://doi.org/10.62713/aic.4083","url":null,"abstract":"<p><strong>Aim: </strong>To assess and compare the short-term impact of clear aligners and fixed appliances on oral, psychological and physical health of patients undergoing orthognathic surgery.</p><p><strong>Methods: </strong>A total of 60 patients who underwent orthognathic surgery between 2021 and 2024 were invited to fill out questionnaires. These patients who were diagnosed with skeletal malocclusion and required a combined surgical and orthodontic treatment approach were divided into clear aligners (CA) and fixed appliances (FA) groups. Oral, psychological and physical health were used to evaluate the quality of life (QoL) multidimensionally by 36-item Short-Form Health Survey (SF-36) and 14-item Short-Form Oral Health Impact Profile (OHIP-14) at two time points: preoperative (T0) and 2 weeks postoperative (T1). Comparative analyses of OHIP-14 and SF-36 scores were conducted between the two cohorts.</p><p><strong>Results: </strong>The OHIP-14 total scores exhibited a notable increase from T0 to T1 in both the CA and FA groups, whereas the physical health summary (PCS) and mental health summary (MCS) scores decreased from T0 to T1. Significant differences in the OHIP-14 total scores, PCS and MCS (p < 0.0001) were observed between the two groups at T1, demonstrating better postoperative QoL in the CA group. Significant negative correlations between age and PCS were observed in both groups (r < -0.5, p < 0.0001) at T1. Age demonstrated significant correlation with MCS in the FA group (r < -0.5, p < 0.0001) at T1. A longer duration of presurgical orthodontics treatment was associated with higher OHIP-14 scores in the FA group (r > 0.3, p < 0.05) and lower MCS scores in both FA and CA groups (r < -0.3, p < 0.05).</p><p><strong>Conclusions: </strong>Compared to traditional orthodontics with fixed appliances, patients managed with clear aligners after orthognathic surgery had better oral, mental, and physical QoL.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 6","pages":"731-741"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influencing Factors and Prediction Model of Postoperative Delirium for Elderly Femoral Neck Fracture Patients Under Remimazolam Intrathecal Anesthesia. 雷马唑仑鞘内麻醉对老年股骨颈骨折患者术后谵妄的影响因素及预测模型。
IF 0.9 4区 医学
Annali italiani di chirurgia Pub Date : 2025-01-01 DOI: 10.62713/aic.3927
Xiufeng Liu, Zhitao Wu, Juan Liu
{"title":"Influencing Factors and Prediction Model of Postoperative Delirium for Elderly Femoral Neck Fracture Patients Under Remimazolam Intrathecal Anesthesia.","authors":"Xiufeng Liu, Zhitao Wu, Juan Liu","doi":"10.62713/aic.3927","DOIUrl":"https://doi.org/10.62713/aic.3927","url":null,"abstract":"<p><strong>Aim: </strong>This study aims to explore the factors affecting postoperative delirium (POD) in elderly femoral neck fracture (FNF) patients under intrathecal anesthesia with remimazolam and to construct a prediction model.</p><p><strong>Methods: </strong>A retrospective study was conducted on 140 eligible patients who were diagnosed with FNFs in our hospital from January 2022 to October 2024 and underwent surgical treatment under intrathecal anesthesia with remimazolam. All individuals were grouped into a delirium group and a non-delirium group according to the occurrence of POD. The included patients were randomly stratified into a training set and a validation set at a ratio of 7:3. Clinical data were collected, and influencing factors were screened using various statistical methods. A nomogram model was constructed to evaluate its performance.</p><p><strong>Results: </strong>Apparent differences between the groups were identified in glucose, lactate level, oxygen partial pressure (PO<sub>2</sub>), Glasgow Coma Scale (GCS) result, and alcohol consumption. The key factors used in constructing the prediction model included glucose (odds ratio [OR] = 1.011, 95% confidence interval [CI]: 0.980-1.024, p = 0.056), lactate (OR = 1.726, 95% CI: 1.252-2.660, p = 0.003), PO<sub>2</sub> (OR = 0.988, 95% CI: 0.977-0.996, p = 0.007), GCS score (OR = 0.346, 95% CI: 0.184-0.550, p < 0.001), and alcohol consumption (OR = 3.140, 95% CI: 0.904-12.310, p = 0.081). The model exhibited favorable discriminative ability, with the training set having an area under the curve (AUC) of 0.882 (95% CI: 0.784-0.952) and the validation set an AUC of 0.941 (95% CI: 0.877-1.000). The calibration curve revealed a strong concordance between the predicted and actual values, suggesting good accuracy. Based on the decision curve analysis (DCA) curve, the model exhibited a remarkable capacity in predicting POD in both the training and the validation sets.</p><p><strong>Conclusions: </strong>The model constructed on the basis of multiple key influencing factors identified in this study was proved to be helpful for the early recognition of high-risk patients for POD, laying a foundation for personalized perioperative management to lessen the incidence of delirium and ameliorate the prognosis. However, this investigation has limitations, requiring optimization and improvement in the future.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 6","pages":"811-823"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Del Nido Cardioplegia Versus Plegisol Solution on Myocardial Protection in Cardiopulmonary Bypass. 德尔尼多停搏液对体外循环心肌保护的影响。
IF 0.9 4区 医学
Annali italiani di chirurgia Pub Date : 2025-01-01 DOI: 10.62713/aic.3817
Bişar Amaç, Ertuğrul Ertuğrul, Mustafa Abanoz, Mesut Engin
{"title":"Effect of Del Nido Cardioplegia Versus Plegisol Solution on Myocardial Protection in Cardiopulmonary Bypass.","authors":"Bişar Amaç, Ertuğrul Ertuğrul, Mustafa Abanoz, Mesut Engin","doi":"10.62713/aic.3817","DOIUrl":"https://doi.org/10.62713/aic.3817","url":null,"abstract":"<p><strong>Aim: </strong>This study aimed to compare the efficacy of the routinely used modified del Nido cardioplegia and Plegisol® solution in myocardial protection.</p><p><strong>Methods: </strong>In this retrospective study, patients who underwent cardiopulmonary bypass (CPB) guided cardiac surgery and received del Nido cardioplegia solution (Group 1) and Plegisol® solution (Group 2) were compared in terms of early clinical data and myocardial protection.</p><p><strong>Results: </strong>This study included 68 patients with similar demographic characteristics who received 38 modified del Nido cardioplegia and 30 Plegisol® solutions. Creatine kinase-myocardial bound (CK-MB) and cardiac troponin T (CTnT) levels on postoperative day 1 and CTnT levels on postoperative day 5 were higher in Group 2 and there was a significant difference between the groups (p = 0.025, p = 0.001, p = 0.001, respectively). In addition, the postoperative inotrope requirement and postoperative vasoactive-inotropic score were higher in Group 2 and there was a significant difference between the two groups (p = 0.004, p = 0.002, respectively).</p><p><strong>Conclusions: </strong>In this study, the del Nido cardioplegia solution was found to be more advantageous regarding the need for intracardiac defibrillation and myocardial necrosis, although it showed similar results in some points when compared with the Plegisol® solution.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 4","pages":"488-495"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143960749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Study on Endometrial Polyps Recurrence Post-Hysteroscopic Resection: Identification of Influencing Factors and Development of a Predictive Model. 宫腔镜切除后子宫内膜息肉复发的研究:影响因素的确定和预测模型的建立。
IF 0.9 4区 医学
Annali italiani di chirurgia Pub Date : 2025-01-01 DOI: 10.62713/aic.3622
Zhuomin Wang, Tao Sun, Jian Xu
{"title":"A Study on Endometrial Polyps Recurrence Post-Hysteroscopic Resection: Identification of Influencing Factors and Development of a Predictive Model.","authors":"Zhuomin Wang, Tao Sun, Jian Xu","doi":"10.62713/aic.3622","DOIUrl":"10.62713/aic.3622","url":null,"abstract":"<p><strong>Aim: </strong>This study aimed to explore influencing factors and develop a predictive model of endometrial polyps (EP) recurrence after hysteroscopic resection.</p><p><strong>Methods: </strong>This retrospective study included 180 patients who underwent hysteroscopic resection for EP between January 2021 to December 2023. The patients were divided into a modeling group (n = 135) and a validation group (n = 45) in a 3:1 ratio. The patients in the modeling group were further divided into a recurrence group (n = 35) and a non-recurrence group (n = 100) based on whether their polyps recurred. General information on patients was compared between the two groups. Univariate and multiple logistic regression analyses were conducted to identify factors influencing EP recurrence post-hysteroscopic resection. A predictive model was developed, and the receiver operating characteristic (ROC) curve analysis was performed to determine the clinical utility of the model.</p><p><strong>Results: </strong>Comparison of baseline characteristics between the modeling and validation groups showed no statistically significant differences (p > 0.05). However, 35 patients in the modeling group had recurrence, while 12 patients experienced recurrence in the validation group. Binary logistics regression analysis revealed matrix metalloproteinase-9 (MMP-9)/tissue inhibitor of metalloproteinase-1 (TIMP-1), hypoxia-inducible factor-1α (HIF-1α) and platelet-derived growth factor (PDGF) as independent predictors for polyp recurrence (p < 0.05). Furthermore, a model formula, p = eZ/1 + eZ, was developed. The slope of the calibration curve of this model in both groups were straight lines close to 1, indicating that the model's predicted recurrence risk strongly agreed with the actual risk. ROC analysis demonstrated that the area under the curve in the modeling group was 0.902, with standard error of 0.028 (95% confidence interval (CI): 0.885-0.954). The model yielded the Youden value of 0.79, with a sensitivity of 82.96% and a specificity of 95.66%. Moreover, the area under the curve in the validation group was 0.871, with a standard error of 0.040 (95% CI: 0.859-0.920). However, the model showed the Youden value of 0.59, with a sensitivity of 79.29% and a specificity of 79.96%. The Decision Curve Analysis (DCA) demonstrated significant clinical advantages of the model.</p><p><strong>Conclusions: </strong>This study identified the influencing factors of EP recurrence and successfully constructed a predictive model based on these factors. After validation, the model demonstrates significant clinical utility.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 1","pages":"40-46"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142999044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gastrointestinal Complications and Laparotomy after Cardiac Surgery: A Retrospective Cohort Study. 心脏手术后胃肠道并发症和剖腹手术:一项回顾性队列研究。
IF 0.9 4区 医学
Annali italiani di chirurgia Pub Date : 2025-01-01 DOI: 10.62713/aic.3819
Thomas French, Dimitrios Damaskos, Darja Clinch, Charilaos-Panagiotis Koutsogiannidis
{"title":"Gastrointestinal Complications and Laparotomy after Cardiac Surgery: A Retrospective Cohort Study.","authors":"Thomas French, Dimitrios Damaskos, Darja Clinch, Charilaos-Panagiotis Koutsogiannidis","doi":"10.62713/aic.3819","DOIUrl":"10.62713/aic.3819","url":null,"abstract":"<p><strong>Aim: </strong>Gastrointestinal (GI) complications following cardiac surgery are infrequent, but associated with high rates of postoperative mortality. The aim of our study was to identify risk factors predisposing patients to GI complications following cardiac surgery and describe the outcomes of patients suffering a GI complication.</p><p><strong>Methods: </strong>This was a retrospective cohort study of 6769 consecutive patients undergoing cardiac surgeries (at least one of coronary artery bypass grafting (CABG), aortic valve replacement, mitral valve replacement, or surgery on thoracic aorta) at a single Scottish centre between 1 January 2015 and 27 September 2023. Cohort demographics, intra-operative details and postoperative outcomes were compared between patients who did and who did not experience a gastrointestinal GI complication.</p><p><strong>Results: </strong>Patients who experienced a GI complication had greater rates of thirty-day mortality (14.4% vs 2.4%, p < 0.001) and in-hospital mortality (6.8% vs 1.1%, p < 0.001) compared with those who did not. We identified previous percutaneous coronary intervention (PCI) (Odds ratio (OR) 2.27 [1.24-4.17], p = 0.007) and combined cardiac surgery (OR 1.67 [1.02-2.74], p = 0.043) as two risk factors for developing a GI complication, in addition to several previously identified risk factors (postoperative atrial fibrillation, postoperative vascular complication, use of pre-operative inotropes and increased age).</p><p><strong>Conclusions: </strong>GI complications frequently occur in elderly, co-morbid patients and in conjunction with other complications. Particularly lethal are mesenteric ischemia, GI bleeding, and small bowel obstruction. Extra caution should be observed in the patient group undergoing more than one cardiac procedure or those with a prior history of coronary artery disease. Prompt emergency laparotomy is a potentially life-saving intervention in promptly diagnosed patients, but confers a high risk of intra-operative and thirty-day mortality.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 3","pages":"409-420"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Combining Ultrasound Parameter and the Caprini Score on Predicting Lower Extremity Deep Venous Thrombosis After Orthopedic Surgery. 超声参数与卡普里尼评分相结合对预测矫形外科手术后下肢深静脉血栓形成的影响
IF 0.9 4区 医学
Annali italiani di chirurgia Pub Date : 2025-01-01 DOI: 10.62713/aic.3861
Xi Chen, Yungwei Chi, Shengjun Ta, Li An, Fen Gu, Feng Tian, Ming Yan, Liwen Liu
{"title":"Impact of Combining Ultrasound Parameter and the Caprini Score on Predicting Lower Extremity Deep Venous Thrombosis After Orthopedic Surgery.","authors":"Xi Chen, Yungwei Chi, Shengjun Ta, Li An, Fen Gu, Feng Tian, Ming Yan, Liwen Liu","doi":"10.62713/aic.3861","DOIUrl":"10.62713/aic.3861","url":null,"abstract":"<p><strong>Aims: </strong>This study combined a new ultrasound venous filling degree (VFD) parameter with the Caprini score to assess the clinical value of the Caprini score in predicting deep venous thrombosis (DVT) of the lower extremities.</p><p><strong>Methods: </strong>This retrospective study included 150 inpatients undergoing orthopedic lower extremity surgery at the First Affiliated Hospital of the Air Force Medical University between June 2023 and June 2024. They included 41 (27.3%) cases of knee arthroplasty, 32 (21.3%) hip arthroplasty, 30 (20%) knee arthroscopy, 28 (18.7%) lower limb fractures, 12 (8%) bone tumor, and 7 (4.7%) cases of other surgery types. The data collected involved preoperative vein diameter, flow velocity, blood flow, venous lumen cross-sectional perimeter (C), lumen cross-sectional area (A), C2/A ratio (VFD) of the common femoral vein (CFV), femoral vein (FV), and popliteal vein (POV). The postoperative sonographic parameters and clinical data were compared between the DVT and non-DVT groups. Receiver operating characteristic (ROC) curve of parameters was evaluated as predictive values for DVT. Additionally, the C2/A ratio was combined with the Caprini score to assess their combined impact on DVT prediction.</p><p><strong>Results: </strong>There were significant differences in ultrasound parameters of CFV inner diameter, CFV blood flow, CFV-C, CFV-A, CFV-C2/A, FV blood flow, FV-C, FV-C2/A, POV blood flow, POV-C, POV-A, and POV-C2/A between the DVT group (24.7%, 37/150) and the non-DVT group (75.3%, 113/150) (all p < 0 .05). Area under curve (AUC) for the C2/A (CFV, FV, and POV) were 0.939 (95% confidence interval (CI): 0.888-0.972, p < 0.001), 0.937 (95% CI: 0.886-0.970, p < 0.001), and 0.917 (95% CI: 0.861-0.956, p < 0.001), respectively. When the Caprini score >2, an AUC for predicting DVT was 0.844 (95% CI: 0.776-0.899, p < 0.001). The AUC of the Caprini score >2 combined with C2/A (CFV, FV, and POV) were 0.953 (95% CI: 0.905-0.981, p < 0.001), 0.965 (95% CI: 0.922-0.988, p < 0.001), and 0.948 (95% CI: 0.900-0.978, p < 0.001), respectively.</p><p><strong>Conclusions: </strong>The ultrasound parameter of VFD-C2/A shows a high predictive value for DVT in patients undergoing orthopedic surgery. Combined with the Caprini score, the predictive value of DVT may be further enhanced compared to using the Caprini score alone.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 3","pages":"380-390"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metastatic Lymph Node Ratio in Right-Sided Colon Cancers Associated With Decreased Overall Survival. 右侧结肠癌的淋巴结转移率与总生存率降低相关。
IF 0.9 4区 医学
Annali italiani di chirurgia Pub Date : 2025-01-01 DOI: 10.62713/aic.3937
Kenan Buyukasık, Esin Kaplan, Mert Guler, Rozan Kaya, Aziz Ari, Omer Akay
{"title":"Metastatic Lymph Node Ratio in Right-Sided Colon Cancers Associated With Decreased Overall Survival.","authors":"Kenan Buyukasık, Esin Kaplan, Mert Guler, Rozan Kaya, Aziz Ari, Omer Akay","doi":"10.62713/aic.3937","DOIUrl":"https://doi.org/10.62713/aic.3937","url":null,"abstract":"<p><strong>Aim: </strong>The aim of this study was to investigate the effect of metastatic lymph node ratio (mLNR) on overall survival after curative resection in patients with right-sided colon cancer.</p><p><strong>Methods: </strong>Patients diagnosed with right-sided colon cancer and treated at Istanbul Teaching and Research Hospital between 2012 and 2017 were retrospectively analyzed. Variables including age, sex, total number of lymph nodes removed, metastatic lymph node ratio, disease stage, tumor location, and patient morbidity were compared with overall survival. Kaplan-Meier survival analysis and Cox regression analysis were used to evaluate the impact of these variables on overall survival.</p><p><strong>Results: </strong>A total of 129 patients were included in this study. By the end of the follow-up period, 51 patients (39.5%) had died. Receiver operating characteristic (ROC) analysis identified a cut-off value for mLNR at 0.0801 (p < 0.001), with 39 patients (30.2%) having an mLNR greater than this threshold. Patients with a high mLNR exhibited significantly shorter overall survival (20.3 months, 95% confidence interval (CI): 12.0-28.6) compared to those with a lower mLNR (106.6 months, 95% CI: 98.4-114.8) (p < 0.001). Furthermore, overall survival was significantly lower in patients with advanced-stage tumors, highlighting the prognostic importance of tumor, node, and metastasis (TNM) staging system. In multivariate Cox regression analysis, TNM stage (hazard ratio (HR) = 50.229, 95% CI: 6.678-372.242, p < 0.001) and mLNR (HR = 3.136, 95% CI: 1.843-5.337, p < 0.001) were identified as independent prognostic factors for overall survival.</p><p><strong>Conclusions: </strong>This study underscores that in right-sided colon cancer, the mLNR and TNM stage provide critical prognostic insights, independent of the total number of lymph nodes removed. These findings support the use of mLNR as a practical and reliable tool for refining prognostic assessments and guiding personalized treatment strategies, emphasizing its potential role in clinical decision-making.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 6","pages":"783-789"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Appendectomy in the Training Program of General Surgery: Entrustable Professional Activity? 普通外科培训计划中的阑尾切除术:可信赖的专业活动?
IF 0.9 4区 医学
Annali italiani di chirurgia Pub Date : 2025-01-01 DOI: 10.62713/aic.3957
Anna Rossetto, Vittoria Morinelli, Davide Muschitiello, Rosanna Quattrin, Giovanni Terrosu, Vittorio Bresadola
{"title":"Appendectomy in the Training Program of General Surgery: Entrustable Professional Activity?","authors":"Anna Rossetto, Vittoria Morinelli, Davide Muschitiello, Rosanna Quattrin, Giovanni Terrosu, Vittorio Bresadola","doi":"10.62713/aic.3957","DOIUrl":"10.62713/aic.3957","url":null,"abstract":"<p><strong>Aim: </strong>The training of medical specialists is a decisive issue for the quality of medical practice. Autonomization in simple procedures and applying the peer education concept seem promising, particularly for general surgery. With this work, we wanted to assess whether there are differences between appendectomy operations performed by differently composed teams with the active involvement of resident doctors at a university centre.</p><p><strong>Methods: </strong>We retrospectively analyzed the laparotomies and laparoscopic appendicectomies carried out at the Udine Surgery Clinic over a period of 10 years. The interventions were divided into groups according to the experience of the surgical team that performed them: G1 (consultant), G2 (senior resident + consultant), G3 (junior resident + consultant), and G4 (junior resident + senior resident).</p><p><strong>Results: </strong>510 appendectomy procedures were considered for the present analysis. 214 (42.0%) were performed by G1, 139 (27.3%) by G2, 79 (15.5%) by G3 and 78 (15.3%) by G4 group. No difference between the groups was shown in terms of complications, reinterventions, readmissions, length of stay, and duration of surgery. A statistically significant difference was shown in the age of the observed population with respect to the degree of experience of the surgical teams: younger patients were mainly operated on by more experienced teams, and in particular, pediatric laparoscopic appendectomy was performed mainly by consultants.</p><p><strong>Conclusions: </strong>Appendectomy surgery can be performed by teams with varying levels of experience and is an example of an activity that can be used in Peer Education. It allows for the empowerment of younger residents and the autonomization of older residents in maintaining a medically, ethically, and legally correct standard of safe clinical practice.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 2","pages":"269-276"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143432248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact of Early and Delayed Fat Transplantation on Scar Quality in Post-Traumatic Reconstruction. 早期和延迟脂肪移植对创伤后重建瘢痕质量的影响。
IF 0.9 4区 医学
Annali italiani di chirurgia Pub Date : 2025-01-01 DOI: 10.62713/aic.3889
Jing Liu, Chang Liu, Yangang Song, Ting Shang, Chen Yang, Hongyu Yin, Yanfu Han
{"title":"The Impact of Early and Delayed Fat Transplantation on Scar Quality in Post-Traumatic Reconstruction.","authors":"Jing Liu, Chang Liu, Yangang Song, Ting Shang, Chen Yang, Hongyu Yin, Yanfu Han","doi":"10.62713/aic.3889","DOIUrl":"https://doi.org/10.62713/aic.3889","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate the effects of early versus delayed fat transplantation on post-traumatic scars using adipose-derived stem cells (ADSCs) to enhance scar quality and address the aesthetic and psychological challenges in reconstructive surgery.</p><p><strong>Methods: </strong>This retrospective cohort study included 223 patients treated at Capital Medical University Beijing Shijitan Hospital between June 2022 and June 2023. Scar quality was evaluated using the Vancouver Scar Scale (VSS) and scar width measurements at 1, 3, and 4 months postoperatively. Complications were monitored during hospital stays and follow-up visits, while Quality of Life was assessed using the World Health Organization Quality of Life brief version (WHOQOL-BREF).</p><p><strong>Results: </strong>A retrospective cohort study of 223 patients with post-traumatic scars was conducted to compare the outcomes of early (n = 108) versus delayed (n = 115) fat grafting. Scar width reduction was significantly greater in the early group at 3 months (1.19 ± 0.30 cm) and 4 months (1.97 ± 0.58 cm) compared to the delayed group (1.31 ± 0.34 cm at 3 months and 2.15 ± 0.55 cm at 4 months; p < 0.05). The early group also demonstrated better VSS scores at 3 months (6.35 ± 1.26) and 4 months (2.16 ± 0.78) than the delayed group (6.81 ± 1.48 at 3 months and 2.37 ± 0.28 at 4 months; p < 0.05). However, the early group exhibited a higher complication rate (9.26% vs. 2.61%; p = 0.034). No significant difference was found in Quality of Life scores between the two groups.</p><p><strong>Conclusions: </strong>Early fat transplantation improves scar quality but is associated with a higher complication rate.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 4","pages":"505-513"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143961024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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