{"title":"Clinical Application and Technological Advances of Tracheal Intubation in the Lateral Position: A Narrative Review.","authors":"Huaying Wei, Xiaoyu Zheng","doi":"10.62713/aic.4089","DOIUrl":"10.62713/aic.4089","url":null,"abstract":"<p><p>Securing an airway through tracheal intubation is crucial in clinical anesthesia and emergency medicine. However, lateral position surgeries or emergency intubation bring extra challenges, such as tricky airways, accidental tube displacement, and complications associated with a patient's positional adjustment under anesthesia. Intubating in the lateral position effectively addresses these challenges by matching the individual's posture to the procedural demands. This review systematically examines the technical characteristics, clinical applications, method selection, equipment choice, and current innovations in lateral-position tracheal intubation. It focuses on exploring its strength in complex and specialized cases and analyzing the limitations and potential improvements in current practices. This review aims to provide healthcare professionals with comprehensive theoretical insights and practical guidance, further promoting the application and widespread adoption of tracheal intubation in the lateral position in clinical settings.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 9","pages":"1159-1166"},"PeriodicalIF":0.9,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145068893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HuanLi Zeng, Xiu Wang, Yi Xiao, ShangYu Xie, ChuanRen Zhuang
{"title":"Analysis of the Influencing Factors of Postoperative Lymphedema of Breast Cancer and the Influence of Axillary Reverse Mapping on Edema and Postoperative Quality of Life.","authors":"HuanLi Zeng, Xiu Wang, Yi Xiao, ShangYu Xie, ChuanRen Zhuang","doi":"10.62713/aic.3892","DOIUrl":"10.62713/aic.3892","url":null,"abstract":"<p><strong>Aim: </strong>Postoperative lymphedema was a common and debilitating complication following breast cancer surgery, which significantly affects quality of life. This study analyzes the risk factors associated with lymphedema and evaluates the effectiveness of axillary reverse mapping (ARM) in reducing its incidence and improving quality of life.</p><p><strong>Methods: </strong>For this retrospective cohort study, 232 breast cancer patients who underwent axillary dissection between January 2022 and January 2023 were recruited. Patients were classified into the lymphedema group (n = 54) and the control group (n = 178) based on edema occurrence. Influencing factors such as body mass index, surgical techniques, and adjuvant therapies were analyzed. To assess ARM's impact on lymphedema and quality of life, patients were also divided into a mapping group (n =133) and the control group (n = 99). Lymphedema stages were evaluated according to the International Lymphatic Society consensus, and quality of life was assessed using the Quality of Working Life Questionnaire for Cancer Survivors (QWLQ-CS), Breast Cancer Survivors Resilience Scale (BCRS), and Strategies Used by People to Promote Health (SUPPH) scale.</p><p><strong>Results: </strong>The results showed that chemotherapy (odds ratios [OR]: 4.063; p < 0.001) and radiotherapy (OR: 3.358; p < 0.001) were significant risk factors for lymphedema. ARM was associated with a reduced risk of lymphedema (OR: 0.322, p = 0.004). A higher proportion of patients in the mapping group were classified as having Stage 0 lymphedema (86.46%) compared to the control group (63.67%). For the mapping group, the QWLQ-CS was 71.04 ± 12.31 (p = 0.041), BCRS was 23.89 ± 6.32 (p = 0.003), and SUPPH was 85.65 ± 12.57 (p = 0.001), which were significantly higher than the control group.</p><p><strong>Conclusions: </strong>Postoperative lymphedema risk in breast cancer patients is influenced by chemotherapy and radiotherapy, with ARM proving beneficial in reducing incidence and enhancing postoperative quality of life.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 9","pages":"1226-1233"},"PeriodicalIF":0.9,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145068938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An Interpretable Deep Learning Framework for Preoperative Classification of Lung Adenocarcinoma on CT Scans: Advancing Surgical Decision Support.","authors":"Qiang Shi, Yufeng Liao, Jie Li, Hongbo Huang","doi":"10.62713/aic.4239","DOIUrl":"10.62713/aic.4239","url":null,"abstract":"<p><strong>Aim: </strong>Lung adenocarcinoma remains a leading cause of cancer-related mortality, and the diagnostic performance of computed tomography (CT) is limited when dependent solely on human interpretation. This study aimed to develop and evaluate an interpretable deep learning framework using an attention-enhanced Squeeze-and-Excitation Residual Network (SE-ResNet) to improve automated classification of lung adenocarcinoma from thoracic CT images. Furthermore, Gradient-weighted Class Activation Mapping (Grad-CAM) was applied to enhance model interpretability and assist in the visual localization of tumor regions.</p><p><strong>Methods: </strong>A total of 3800 chest CT axial slices were collected from 380 subjects (190 patients with lung adenocarcinoma and 190 controls, with 10 slices extracted from each case). This dataset was used to train and evaluate the baseline ResNet50 model as well as the proposed SE-ResNet50 model. Performance was compared using accuracy, Area Under the Curve (AUC), precision, recall, and F1-score. Grad-CAM visualizations were generated to assess the alignment between the model's attention and radiologically confirmed tumor locations.</p><p><strong>Results: </strong>The SE-ResNet model achieved a classification accuracy of 94% and an AUC of 0.941, significantly outperforming the baseline ResNet50, which had an 85% accuracy and an AUC of 0.854. Grad-CAM heatmaps produced from the SE-ResNet demonstrated superior localization of tumor-relevant regions, confirming the enhanced focus provided by the attention mechanism.</p><p><strong>Conclusions: </strong>The proposed SE-ResNet framework delivers high accuracy and interpretability in classifying lung adenocarcinoma from CT images. It shows considerable potential as a decision-support tool to assist radiologists in diagnosis and may serve as a valuable clinical tool with further validation.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 9","pages":"1206-1217"},"PeriodicalIF":0.9,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145068972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Value of the Donated Body: Why Cadaveric Training Remains Irreplaceable in Surgical Education.","authors":"Raquel Diaz, Piero Fregatti, Guglielmo Mantica","doi":"10.62713/aic.4285","DOIUrl":"https://doi.org/10.62713/aic.4285","url":null,"abstract":"","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 9","pages":"1131-1132"},"PeriodicalIF":0.9,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145068927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Incidental Discovery of Tracheal Diverticulum During Thyroidectomy: A Report of Seven Cases.","authors":"Wen He, Liyu Qian, Rongli Xie, Jianhua Gu, Xujian Xing, Dongjie Shen, Min Ding, Dan Xu, Donghang Huang, Jing Fang, Jian Fei","doi":"10.62713/aic.4206","DOIUrl":"10.62713/aic.4206","url":null,"abstract":"<p><strong>Aim: </strong>Tracheal diverticulum, an air-filled sac typically located on the right posterolateral aspect of the trachea, has an unclear etiology. This study evaluates the clinical management and outcomes of incidentally detected tracheal diverticula in patients with papillary thyroid carcinoma, emphasizing the need for preoperative diagnosis and selective treatment.</p><p><strong>Case presentation: </strong>Within our multi-center thyroid surgery cohort, seven cases of tracheal diverticula were incidentally discovered during thyroidectomy, with preoperative diagnosis achieved in only a subset of patients. Some tracheal diverticula were surgically excised, allowing for histopathological examination, whereas others were left in situ. All patients recovered without postoperative complications.</p><p><strong>Results: </strong>Histopathological examination of the resected tracheal diverticula confirmed benign pathology. All patients, including those with untreated tracheal diverticula, remained asymptomatic during follow-up, with no tracheal abnormalities or complications observed. High-resolution computed tomography and three-dimensional reconstruction technology proved effective for the preoperative diagnosis of tracheal diverticulum.</p><p><strong>Conclusions: </strong>Routine surgical treatment is unnecessary for asymptomatic patients, with resection of tracheal diverticulum reserved for symptomatic cases. Diagnostic approaches such as high-resolution computed tomography and three-dimensional reconstruction serve as essential preoperative assessments before thyroidectomy, enabling accurate diagnosis of tracheal diverticulum.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 9","pages":"1146-1154"},"PeriodicalIF":0.9,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145068975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of Nutritional Support Under Comprehensive Nursing on Gastrointestinal Function in Patients With Gastroparesis Syndrome Following Radical Gastrectomy for Gastric Cancer.","authors":"Yanran Qin, Congxue Xie","doi":"10.62713/aic.4173","DOIUrl":"10.62713/aic.4173","url":null,"abstract":"<p><strong>Aim: </strong>This study aimed to evaluate the effect of nutritional support intervention, implemented within the framework of comprehensive nursing, on gastrointestinal function and primary symptom indices in patients with gastroparesis syndrome following radical gastrectomy for gastric cancer.</p><p><strong>Methods: </strong>Based on existing case records, the clinical data of 225 patients who underwent radical gastrectomy (distal gastrectomy + Billroth II anastomosis) for gastric cancer at our hospital between October 2022 and October 2024 were retrospectively analyzed. After propensity score matching (PSM) at a 1:1 ratio, 160 patients were included in the final analysis and among them, 80 cases in the observation group and 80 cases in the control group. The control group received conventional nursing care, while the observation group received nutritional support intervention within a comprehensive nursing model. Levels of gastrointestinal hormones, severity of gastroparesis symptoms, gastrointestinal function, and nursing satisfaction were compared between the two groups before and after the intervention.</p><p><strong>Results: </strong>Two weeks post-intervention, the levels of motilin (MTL) and gastrin (GAS) in the observation group were significantly lower than in the control group, whereas the pepsinogen I (PG I) level was significantly higher (p < 0.05). Following two weeks of treatment, the observation group demonstrated significantly lower Gastroparesis Cardinal Symptom Index (GCSI) scores than the control group (p < 0.05). Additionally, the observation group had shorter gastric drainage duration, earlier first flatus, quicker resumption of normal eating, and faster symptom resolution compared to the control group (p < 0.05). Nursing satisfaction was significantly higher in the observation group (p < 0.05).</p><p><strong>Conclusions: </strong>Nutritional support intervention delivered through comprehensive nursing for patients with gastroparesis syndrome after radical gastrectomy for gastric cancer enhances gastric function, modulates gastrointestinal hormone levels, alleviates gastroparesis symptoms, and improves nursing satisfaction.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 9","pages":"1234-1246"},"PeriodicalIF":0.9,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145068990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of Restrictive Blood Transfusion Strategy on Perioperative Prognosis in Elderly Orthopedic Surgery Patients With Preoperative Anemia.","authors":"Wei Ren, Jie Yao","doi":"10.62713/aic.4234","DOIUrl":"10.62713/aic.4234","url":null,"abstract":"<p><strong>Aim: </strong>Preoperative anemia remains a common condition in elderly patients undergoing orthopedic surgery, and the choice of transfusion strategy may affect perioperative outcomes. Therefore, this study aims to investigate the effect of a restrictive transfusion strategy on perioperative outcomes in this population.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 782 preoperatively anemic patients (aged ≥60 years) who underwent hip replacement, knee replacement, or spine surgery at Xuanwu Hospital Capital Medical University, China, between January 2018 and June 2024. Patients were categorized into the restrictive (n = 380) and liberal (n = 402) transfusion strategy groups. Perioperative indicators included estimated blood loss, transfusion volume, length of hospital stay, as well as additional relevant variables. Primary outcomes were 30-day all-cause mortality, transfusion-related adverse reactions, and postoperative infection rates. Secondary outcomes included postoperative hemoglobin levels, readmission rates, reoperation rates, thrombosis, and cardiovascular events.</p><p><strong>Results: </strong>In hip replacement and spine surgery patients, the estimated blood loss was significantly lower in the restrictive transfusion group than in the liberal transfusion group (p < 0.001), while higher in knee replacement patients (p < 0.001). The restrictive transfusion strategy reduced transfusion requirements and shortened hospital stay across all surgical types (p < 0.001). No significant difference in 30-day all-cause mortality was observed between the groups (p > 0.05). However, the restrictive transfusion group had significantly lower rates of transfusion-related adverse reactions (1.3% vs. 5.0%, p < 0.001) and infections (2.6% vs. 6.5%, p = 0.017). Additionally, transfusion strategy was identified as an independent risk factor for transfusion-related adverse reactions [odds ratio (OR) = 3.96, 95% CI: 1.468-10.682, p = 0.007)].</p><p><strong>Conclusions: </strong>A restrictive transfusion strategy reduces transfusion volume, minimizes the incidence of transfusion-related adverse reactions and infections. This study supports individualized perioperative anemia management to optimize outcomes in elderly patients.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 9","pages":"1190-1197"},"PeriodicalIF":0.9,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145068981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Impact of Laser Surgery for Vocal Cord Cysts on Patients' Voice Acoustic Analysis Parameters and Inflammatory Response.","authors":"Nijun Chen, Zhihong Shi, Xingmei Sun","doi":"10.62713/aic.3804","DOIUrl":"10.62713/aic.3804","url":null,"abstract":"<p><strong>Aim: </strong>Vocal cord cyst is a common benign proliferative lesion of the vocal cords, usually resulting from excessive use of the voice, environmental pollution, and inflammatory infections. This study aims to explore the differences in the effectiveness of carbon dioxide (CO<sub>2</sub>) laser or surgical treatment for vocal cord cyst patients.</p><p><strong>Methods: </strong>This retrospective study analyzed 81 patients with vocal cord cysts who underwent surgical treatment at Ruijin Hospital, Shanghai Jiao Tong University School of Medicine between July 2021 and July 2024. Among them, 40 patients were treated with CO<sub>2</sub> laser surgery (the laser group), and 41 underwent traditional surgical treatment (the surgery group). The study compared the pre- and post-treatment voice acoustic parameters, aerodynamic parameters, levels of inflammatory factors, stress response indicators, and surgical complications between the two groups.</p><p><strong>Results: </strong>Before surgery, there were no significant differences between the laser group and the surgery group regarding jitter, shimmer, harmonic-to-noise ratio (HNR), maximum phonation time (MPT), mean airflow rate, and subglottic pressure (p > 0.05). However, at 4 weeks post-surgery, the laser group showed lower values for jitter, shimmer, and mean airflow compared to the surgery group (p < 0.05), while the laser group demonstrated a longer MPT compared to the surgery group (p < 0.05). Before surgery, there were no significant differences between the laser and surgery groups regarding the levels of interleukin-6 (IL-6), interleukin-1β (IL-1β), and tumor necrosis factor-α (TNF-α) (p > 0.05). However, at 4 weeks post-surgery, the IL-1β and TNF-α levels in the laser group were lower than those in the surgery group (p < 0.05). Before surgery, there were no significant differences between the laser and surgery groups in Voice Handicap Index (VHI-10) scores and the Grade, Roughness, Breathiness, Asthenia, Strain (GRBAS) scores (p > 0.05). Moreover, the VHI-10 and GRBAS scores were lower in the laser group compared to the surgery group at 4 weeks post-surgery (p < 0.05). Additionally, the complication rates in the laser group were 12.50%, compared to 24.39% in the surgery group, indicating no significant differences (p > 0.05).</p><p><strong>Conclusions: </strong>Both CO<sub>2</sub> laser and conventional surgery for treating vocal cord cysts show favorable outcomes. However, CO<sub>2</sub> laser surgery offers faster recovery of vocal function and is more effective at reducing the inflammatory response.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 9","pages":"1247-1253"},"PeriodicalIF":0.9,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145068978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of Risk Early Warning Management on Postoperative Rehabilitation Quality and Incidence of Delirium in Patients With Unilateral Intertrochanteric Femur Fracture.","authors":"Mingqiang Peng, Caihong Wen, Yuxi Wei, Wei Zhang, Zhenyu Liu, Yanhua Zhang, Songqing Li","doi":"10.62713/aic.4123","DOIUrl":"10.62713/aic.4123","url":null,"abstract":"<p><strong>Aim: </strong>This study aims to assess the impact of risk early warning management on postoperative rehabilitation outcomes in patients with unilateral intertrochanteric femur fracture (UIFF), and to investigate the effect on the incidence of postoperative delirium.</p><p><strong>Methods: </strong>This study included 284 patients with unilateral femoral intertrochanteric fracture admitted between January 2023 and December 2023. The patients received internal fixation with proximal femoral nail (PFN). Patients were divided into two groups: the experimental group (n = 142), which received risk early warning management, and the control group (n = 142), which received routine perioperative management. The coagulation function and self-care ability were evaluated in both groups before (before surgery) and after intervention (10 days after surgery). Furthermore, postoperative complication rate, hip rehabilitation quality, and satisfaction levels were comparatively analyzed between the two study groups.</p><p><strong>Results: </strong>Higher fibrinogen (FBG) and lower D-dimer (D-D) were found in the experimental group compared to the control group (p < 0.05). Furthermore, the experimental group showed a significantly lower incidence of delirium, as well as improved hip rehabilitation quality and self-care ability compared to the control group (p < 0.05). Additionally, the overall satisfaction levels were substantially higher in the experimental group of patients than those observed in the control group (p < 0.05).</p><p><strong>Conclusions: </strong>Risk early warning management can enhance the coagulation function and reduce the risk of postoperative delirium in patients with UIFF. These findings will provide a more reliable safety package for the future surgical treatment of UIFF.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 9","pages":"1198-1205"},"PeriodicalIF":0.9,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145068903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luiz-Sorin Vasiu, Laura Raducu, Cristian Radu Jecan
{"title":"Exploring the Physiological and Demographic Traits of Cutaneous Melanoma in the Romanian Population: A Six-Year Retrospective Cohort Study of 130 Patients.","authors":"Luiz-Sorin Vasiu, Laura Raducu, Cristian Radu Jecan","doi":"10.62713/aic.3918","DOIUrl":"10.62713/aic.3918","url":null,"abstract":"<p><strong>Aim: </strong>This study evaluates the demographic and clinicopathological characteristics of patients diagnosed with cutaneous melanoma in the Romanian population.</p><p><strong>Methods: </strong>This retrospective population-based cohort study analyzed the histopathological parameters of primary cutaneous melanomas in 130 patients treated at the plastic surgery department of our hospital in Bucharest over a six-year period.</p><p><strong>Results: </strong>The incidence of cutaneous melanoma in the cohort increased by approximately 15.6% annually, with a male predominance and a mean diagnosis age of 59.9 years. The majority (73.1%) of cases were within the 51-80 age group. Superficial spreading melanoma accounted for 52.3% of cases, followed by nodular melanoma at 35.4%. The mean Breslow index was 4.745 mm, and 35.4% of cases were diagnosed at stage T4. Spearman's rank correlation analysis demonstrated that the Breslow index was positively correlated with patient age (rho = 0.327, p < 0.001), indicating that older age is associated with higher Breslow index values. Males presented with higher tumor thickness and were diagnosed later than females, on average by a decade.</p><p><strong>Conclusions: </strong>Cutaneous melanoma remains a high-risk malignancy with significant morbidity and mortality. Patients in Romania were diagnosed with thicker tumors compared to Western populations, potentially due to limited awareness and insufficient prevention strategies. These findings underscore the urgent need to improve early detection programs and public education on melanoma in Romania.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 9","pages":"1268-1277"},"PeriodicalIF":0.9,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145068916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}