{"title":"Impact of Preoperative Frailty on Postoperative Functional Recovery and Quality of Life in Elderly Patients With Gastrointestinal Tumors.","authors":"Fujia Xie, Cheng Xi, Guoqing Bao, Bin Yang, Xiaoyu Zheng, Bowen Fu, Zhibin Zheng","doi":"10.62713/aic.4501","DOIUrl":"https://doi.org/10.62713/aic.4501","url":null,"abstract":"<p><strong>Aim: </strong>To examine the impact of preoperative frailty levels on postoperative functional recovery and quality of life in elderly individuals with gastrointestinal tumors, thereby providing evidence to inform perioperative clinical management.</p><p><strong>Methods: </strong>A total of 198 individuals aged ≥60 years who underwent radical resection of gastrointestinal tumors in the Department of General Surgery, The First Affiliated Hospital of Kunming Medical University from January 2019 to January 2024 were retrospectively analyzed. The Tilburg Frailty Indicator (TFI) was utilized to assess preoperative frailty; the Barthel Index was used to evaluate functional recovery at 30 and 90 days postoperatively; and the 12-Item Short-Form Health Survey (SF-12) was adopted to assess quality of life at 90 days postoperatively. Statistical analyses, such as chi-square test, logistic regression, and repeated measures analysis of variance, were performed.</p><p><strong>Results: </strong>The incidence of preoperative frailty was 19.2%, mainly manifested in the physical domain. Age, severe comorbidity (Charlson Comorbidity Index ≥6 points), operative duration ≥180 minutes, and preoperative depression were identified as independent risk factors for preoperative frailty, while habit of regular exercise was a protective factor (<i>p</i> < 0.05). Postoperatively, both the Barthel Index and SF-12 scores in the frailty group were significantly lower compared to the non-frailty group (<i>p</i> < 0.001).</p><p><strong>Conclusions: </strong>Preoperative frailty delays postoperative functional recovery and reduces quality of life in elderly individuals with gastrointestinal tumors. Our findings support the inclusion of TFI in routine preoperative assessment, coupled with the implementation of targeted interventions.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"97 4","pages":"710-718"},"PeriodicalIF":0.9,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147687843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Leonardo Barellini, Virginia Coli, Gianluca Marcaccini
{"title":"Minimally Invasive Nipple Sparing Mastectomy: Exercise in Style or Proof of Concept.","authors":"Leonardo Barellini, Virginia Coli, Gianluca Marcaccini","doi":"10.62713/aic.4505","DOIUrl":"https://doi.org/10.62713/aic.4505","url":null,"abstract":"","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"97 4","pages":"604-606"},"PeriodicalIF":0.9,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147687831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wan-Ping Zhu, Na Zhou, Yi-Na Wang, Jun Zhang, Wei Lin
{"title":"Comparison and Threshold Analysis of the ODET/GTD Ratio Between Patients With and Without Postoperative Sore Throat: A Retrospective Study.","authors":"Wan-Ping Zhu, Na Zhou, Yi-Na Wang, Jun Zhang, Wei Lin","doi":"10.62713/aic.4492","DOIUrl":"https://doi.org/10.62713/aic.4492","url":null,"abstract":"<p><strong>Aim: </strong>This study aimed to retrospectively compare the outer diameter of the endotracheal tube to glottic transverse diameter (ODET/GTD) ratio between patients with and without postoperative sore throat (POST). An optimal ODET/GTD ratio cut-point was explored to provide a reference for endotracheal tube (ETT) selection and potentially help manage the risk of POST.</p><p><strong>Methods: </strong>We reviewed 150 patients in the Post Anesthesia Care Unit (PACU). Among these, 68 patients developed POST and 82 did not. The ODET/GTD ratio was calculated for each patient. This ratio was compared between the two patient groups. Receiver operating characteristic curve (ROC) analysis was performed, and the Youden index was used to identify the optimal ODET/GTD ratio cut-point for predicting POST.</p><p><strong>Results: </strong>The overall incidence of POST was 45.33%. The mean ODET/GTD ratio was significantly lower in patients without POST (1.02 ± 0.06) than in those with POST (1.18 ± 0.08), <i>p</i> < 0.01. ROC analysis identified an optimal ODET/GTD ratio cut-point of 1.10 (Youden index = 0.79) for predicting POST, with a sensitivity of 85% and a specificity of 79%.</p><p><strong>Conclusions: </strong>Our findings suggest that a higher ODET/GTD ratio may contribute to the development of POST. Based on the ROC curve analysis, the ODET/GTD ratio of 1.10 was determined as a potential reference cutoff value for stratifying the risk of POST. These findings suggest that the ODET/GTD ratio may be useful for perioperative risk assessment; however, before applying it to guide the selection of tracheal intubation, further prospective studies and external validation are still needed.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"97 4","pages":"719-724"},"PeriodicalIF":0.9,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147687848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of Preoperative Mindfulness Training Combined With Active Breathing and Circulation Exercises on Pulmonary Function Recovery in Lung Cancer Patients After Lobectomy.","authors":"Luping Yang, Aixia Chen, Lan Li","doi":"10.62713/aic.4474","DOIUrl":"https://doi.org/10.62713/aic.4474","url":null,"abstract":"<p><strong>Aim: </strong>Diminished pulmonary function and psychological distress, which are common following lobectomy in lung cancer patients, represent a hindrance to the overall recovery. This study aimed to retrospectively explore the effects of preoperative mindfulness training combined with active breathing and circulation exercises on postoperative pulmonary function recovery in lung cancer patients undergoing lobectomy.</p><p><strong>Methods: </strong>A retrospective study was conducted on 160 patients who underwent lobectomy at Shaoxing People's Hospital. The samples were divided into two groups based on the type of nursing care received: the control group received standard care, whilst the experimental group received preoperative mindfulness training combined with active breathing and circulation exercises. Evaluation indicators included anxiety and depression levels, physiological parameters (peripheral capillary oxygen saturation [SpO<sub>2</sub>], forced vital capacity [FVC], forced expiratory volume in one second [FEV<sub>1</sub>], maximum voluntary ventilation [MVV], forced expiratory volume in one second, percent of predicted [FEV<sub>1</sub>%pred], forced vital capacity, percent of predicted [FVC%pred], FEV<sub>1</sub>/FVC, arterial oxygen pressure [PaO<sub>2</sub>], and arterial carbon dioxide pressure [PaCO<sub>2</sub>]), exercise tolerance, medication adherence and health-related quality of life (HRQoL).</p><p><strong>Results: </strong>The depression score (2.00 [1.00, 3.00]) and anxiety score (2.00 [1.00, 4.00]) in the experimental group were significantly lower than those in the control group (<i>p</i> < 0.001). Compared with the control group, several physiological indicators showed significant improvement in lung function in the experimental group (<i>p</i> < 0.05), and the Borg scale score (1.00 [0.00, 2.00]) was significantly lower in the experimental group than in the control group (<i>p</i> < 0.001). Regarding exercise tolerance, the post-intervention six-minute walk distance (6MWD) was significantly higher in the experimental group than in the control group (382.10 ± 68.17 vs. 356.24 ± 87.46, <i>p</i> < 0.05). In the experimental group, the proportions of patients with poor, moderate, and good medication adherence after surgery were 5.95%, 26.19%, and 67.86%, respectively. In contrast, the corresponding proportions in the control group were 7.89%, 47.37%, and 44.74%. Medication adherence was significantly higher in the experimental group than in the control group (<i>p</i> < 0.05). Regarding quality of life, the experimental group showed significantly higher scores in the five functional dimensions and the overall healthy quality of life dimension compared to the control group (<i>p</i> < 0.05).</p><p><strong>Conclusions: </strong>Preoperative mindfulness training combined with active breathing and circulation exercises significantly improves the postoperative psychological well-being of patients undergoing lobectomy","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"97 4","pages":"684-693"},"PeriodicalIF":0.9,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147687873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative Efficacy of Uterine Suturing Techniques on Postoperative Recovery Following Repeat Caesarean Section: A Retrospective Cohort Study in Patients With Scarred Uteri.","authors":"Xiaoyan Chen, Juefei Lu","doi":"10.62713/aic.4469","DOIUrl":"https://doi.org/10.62713/aic.4469","url":null,"abstract":"<p><strong>Aim: </strong>The optimal uterine suturing technique for repeat caesarean section in women with a scarred uterus remains controversial, and evidence comparing novel techniques, such as the breakwater suture, with conventional methods in terms of comprehensive recovery is limited. The objective of this study is to investigate the combined effects of single-layer suturing, double-layer suturing, and breakwater suture techniques on postoperative recovery in patients with scarred uteri undergoing repeat caesarean section.</p><p><strong>Methods: </strong>In this retrospective cohort study, 300 pregnant women with scarred uteri undergoing repeat caesarean section at The Maternal and Child Health Care Hospital of Tong Xiang between January 2022 and December 2024 were included. The sample was divided into three groups based on the type of suture used: single-layer suture group (<i>n</i> = 108), double-layer suture group (<i>n</i> = 103), and breakwater suture group (<i>n</i> = 89). Primary outcomes comprised postoperative recovery time, complications, uterine healing status, psychological state, and sleep quality.</p><p><strong>Results: </strong>There were no significant differences in baseline characteristics among the three groups (<i>p</i> > 0.05). Regarding postoperative recovery, the breakwater suture group demonstrated significantly shorter time to anal flatus, time to first ambulation, and postoperative hospital stay compared with both the single-layer and the double-layer suture groups (<i>p</i> < 0.05). Postoperative ultrasound revealed significantly greater uterine segment myometrial thickness in the breakwater suture group compared to the other two groups (<i>p</i> < 0.001). At six months postoperatively, the incidence of uterine diverticulum in the breakwater suture group (4.5%) was significantly lower than that in the single-layer suture group (15.7%); the overall difference among the three groups was statistically significant (<i>p</i> = 0.041). Furthermore, patients in the breakwater suture group demonstrated significantly better postoperative outcomes on the Self-Rating Anxiety Scale (SAS), Self-Rating Depression Scale (SDS), Edinburgh Postnatal Depression Scale (EPDS), and Pittsburgh Sleep Quality Index (PSQI) compared with the other groups (<i>p</i> < 0.001).</p><p><strong>Conclusions: </strong>In repeat caesarean sections in women with scarred uteri, the breakwater suture technique comprehensively promotes postoperative recovery and may be recommended as a suturing method.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"97 4","pages":"694-700"},"PeriodicalIF":0.9,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147687891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Efficacy of UBE-ULBD in Patients With Severe Lumbar Spinal Stenosis and Its Impact on Imaging Manifestations.","authors":"Yiming Zhang, Lu Wang, Xiaoming Hu, Mao Shen","doi":"10.62713/aic.4401","DOIUrl":"https://doi.org/10.62713/aic.4401","url":null,"abstract":"<p><strong>Aim: </strong>This research seeks to evaluate the clinical efficacy of unilateral bilateral endoscopy-unilateral laminotomy for bilateral decompression (UBE-ULBD) in patients with severe lumbar spinal stenosis (LSS) and explore its impact on imaging manifestations.</p><p><strong>Methods: </strong>Fifty patients with severe LSS receiving treatment from January 2023 to June 2024 were included in this study and retrospectively examined. The participants were divided into the experimental group (<i>n =</i> 27) and the control group (<i>n =</i> 23). The control group underwent conventional open surgery, while the experimental group adopted the UBE-ULBD technique. Primary endpoints included perioperative metrics, such as surgical duration, intraoperative blood loss, postoperative drainage, time to first ambulation, and length of hospital stay. Secondary endpoints included visual analogue scale (VAS), Japanese Orthopaedic Association (JOA) scores, Oswestry Disability Index (ODI) scores, Macnab scores, disc height, dural sac area, and complications. All outcomes were assessed at baseline, 1 month, 6 months, and 1 year postoperatively. Additionally, surgical segment fusion, Macnab scores, intervertebral disc height, and dural sac area were assessed at 6 months and 1 year postoperatively, and complications occurring within 1 year postoperatively were documented.</p><p><strong>Results: </strong>In the experimental group, patients experienced shorter surgery duration, reduced intraoperative amount of bleeding, decreased 24-hour wound drainage, shorter antibiotic administration time, earlier ambulation time, and shorter length of hospital stay compared with the control group (<i>p <</i> 0.001). At 6 months and 1 year post-surgery, the intervertebral disc height and dural sac area in the experimental group were significantly higher than those in the control group (<i>p</i> < 0.001). There was no statistically significant difference in the number of non-fused cases postoperatively between the groups (<i>p</i> > 0.05), but the experimental group showed a better distribution of Macnab scores (<i>p</i> < 0.05). The VAS scores for low back pain in the experimental group were significantly lower than those in the control group at 1 month and 6 months postoperatively (<i>p</i> < 0.05), while the VAS scores for leg pain were significantly lower only at 1 month postoperatively (<i>p</i> < 0.05), but there was no significant difference between the two groups at 1 year after surgery (<i>p</i> > 0.05). The JOA score of the experimental group was significantly higher than that of the control group at 1 month postoperatively (<i>p</i> < 0.05); the ODI score of the experimental group was significantly lower than that of the control group at 1 month, 6 months and 1 year postoperatively (<i>p</i> < 0.05). Besides, there was no statistically significant difference in the incidence of complications between the two groups (<i>p</i> > 0.05).</p><p><strong>Conclusions: <","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"97 4","pages":"657-665"},"PeriodicalIF":0.9,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147687756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of Simulation Training Combined With Video Debriefing on Surgical Skill Acquisition and Perioperative Outcomes in Laparoscopic Adrenalectomy.","authors":"Yuzhi Zuo, Yi Zhao, Xingcheng Wu","doi":"10.62713/aic.4488","DOIUrl":"https://doi.org/10.62713/aic.4488","url":null,"abstract":"<p><strong>Aim: </strong>To investigate the effect of a comprehensive training model combining simulation training and video debriefing on improving the surgical skills of surgeons performing laparoscopic adrenalectomy and to evaluate its influence on perioperative outcomes in clinical practice.</p><p><strong>Methods: </strong>This retrospective study included nine surgeons who completed training between January 2021 and December 2024 and 182 laparoscopic adrenalectomies performed by them. All surgeons underwent both a traditional and a comprehensive training phase, combining simulation training with video debriefing. Accordingly, a total of 79 cases were completed during the traditional training phase, and 103 cases were completed during the comprehensive training phase. The theoretical knowledge scores of the surgeons, Objective Structured Assessment of Technical Skills (OSATS) scores, surgical confidence scores, and corresponding perioperative indicators (operation time, intraoperative blood loss, conversion to open surgery, and postoperative recovery indicators) were compared between the two phases.</p><p><strong>Results: </strong>Compared with the traditional training phase, the comprehensive training phase significantly improved the theoretical knowledge scores of the surgeons [43.00 (42.00, 43.00) vs. 41.00 (38.00, 43.00), <i>p</i> = 0.028] and significantly enhanced all dimensions and the total OSATS scores (all <i>p</i> < 0.05). The confidence of the surgeons in \"independently performing surgery\", \"understanding the operation steps\" and \"intraoperative decision-making\" was also significantly increased (all <i>p</i> < 0.05). Regarding clinical outcomes, patients treated during the comprehensive training phase had significantly shorter operation times [82.00 min vs. 107.00 min, <i>p</i> < 0.001], reduced blood loss [64.00 mL vs. 104.00 mL, <i>p</i> < 0.001], and significantly shorter times to first postoperative oral intake [13.00 h vs. 31.00 h, <i>p</i> < 0.001], ambulation [13.00 h vs. 16.00 h, <i>p</i> = 0.002], and postoperative hospital stay [4.00 days vs. 5.00 days, <i>p</i> < 0.001]. No statistically significant difference in the conversion rate to open surgery was observed between the two groups (<i>p</i> = 0.816).</p><p><strong>Conclusions: </strong>The integrated training model combining simulation training and video debriefing effectively improves the theoretical knowledge of surgeons, technical skills, and surgical confidence in laparoscopic adrenalectomy. Notably, these educational improvements were associated with measurable enhancements in real-world surgical performance and improved perioperative patient outcomes. This model represents an efficient surgical training strategy with significant clinical translational value.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"97 4","pages":"701-709"},"PeriodicalIF":0.9,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147687920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association of Postoperative Nadir Haemoglobin Levels With Long-term Adverse Events After Elective Noncardiac Surgery.","authors":"Monir Jawad, Amir Baigi","doi":"10.62713/aic.4416","DOIUrl":"https://doi.org/10.62713/aic.4416","url":null,"abstract":"<p><strong>Aim: </strong>Preoperative anaemia is a well-established risk factor for poor outcomes. However, the impact of postoperative haemoglobin (Hb) levels on long-term outcomes, including mortality and cardiovascular events, remains uncertain. This study aims to assess the independent association between postoperative nadir Hb levels and long-term outcomes, considering the potential interaction with preoperative anaemia status.</p><p><strong>Methods: </strong>This study is a secondary analysis of data from the Myocardial Injury in Noncardiac Surgery in Sweden study, which included patients aged ≥50 years undergoing elective noncardiac surgery. Postoperative Hb levels were measured daily for up to 3 days or until discharge, and the lowest recorded value was used as the primary exposure variable. Multivariable logistic regression analysis was employed to explore the independent association of postoperative nadir Hb with the primary outcome of a composite endpoint comprising all-cause mortality and cardiovascular complications over a one-year period, adjusting for a range of perioperative risk factors, including preoperative anaemia. To account for a potential interaction with preoperative anaemia, an interaction term was added to the model. Secondary outcomes were one-year mortality and one-year cardiovascular morbidity.</p><p><strong>Results: </strong>A total of 1284 patients were included, of whom 521 (40.6%) had preoperative anaemia. The median postoperative nadir Hb level was 102 g·L<sup>-1</sup> (interquartile range 92-114). Postoperative nadir Hb was not independently associated with the composite primary outcome; however, it showed a weak but statistically significant association with one-year mortality (adjusted odds ratio [aOR] 0.98, 95% confidence interval [CI] 0.95-0.99). No significant interaction was found between preoperative anaemia and postoperative nadir Hb. Independent predictors of the primary outcome included university hospital status (aOR 2.83, 95% CI 1.96-4.10), age (aOR 1.05, 95% CI 1.03-1.07), and unplanned postoperative intensive care (aOR 3.17, 95% CI 1.08-9.28).</p><p><strong>Conclusions: </strong>Postoperative nadir Hb levels, within the observed range well above 70 g·L<sup>-1</sup>, were not independently associated with the long-term composite outcome. However, they were weakly associated with one-year mortality. No significant interaction was found between preoperative anaemia and postoperative nadir Hb. These findings highlight the need for further investigation into the clinical significance of postoperative Hb levels in high-risk patients.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"97 4","pages":"753-762"},"PeriodicalIF":0.9,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147687770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elda Chiara Colacchio, Michele Piazza, Giovanni Abruzzino, Augusto D'Onofrio, Franco Grego, Michele Antonello
{"title":"Bailout Maneuvers to Avoid Brain Infarct During Aneurysm Exclusion Using the Nexus™ Endograft: A Case Report.","authors":"Elda Chiara Colacchio, Michele Piazza, Giovanni Abruzzino, Augusto D'Onofrio, Franco Grego, Michele Antonello","doi":"10.62713/aic.4103","DOIUrl":"https://doi.org/10.62713/aic.4103","url":null,"abstract":"<p><p>The aim of this study is to report our experience with a complication that occurred during a single-branch aortic arch endograft deployment for a symptomatic aortic aneurysm exclusion. An 85-year-old patient was diagnosed with an aortic arch and descending aortic aneurysm associated with chest pain and dyspnea. After a multidisciplinary discussion, we selected an endovascular approach using an off-the-shelf device for the arch (Nexus™ endograft; Endospan) with a single branch for the brachiocephalic trunk (BCT). Supra-aortic trunks debranching (right common carotid-left subclavian bypass and left common carotid artery reimplantation) was planned in the same procedure. After an uneventful main module deployment, the release of the ascending graft was followed by the sudden occlusion of the endograft branch. Suspecting the branch coverage by the ascending module, a relining of the branch using the through-and-through guide wire was performed restoring brain perfusion. The post-operative course was uneventful as well during the follow-up (6 months). In our experience, the Nexus™ endograft (Endospan) presents peculiar technical features that provide great main module deployment stability and allow for rapid bailout maneuvers if complications occur.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"97 4","pages":"631-636"},"PeriodicalIF":0.9,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147687821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Research Advances in Cell-Assisted Lipotransfer for Facial and Breast Surgery.","authors":"Mingtu Du, Haiyan Qin, Lianbo Zhang","doi":"10.62713/aic.4487","DOIUrl":"https://doi.org/10.62713/aic.4487","url":null,"abstract":"<p><p>Cell-assisted lipotransfer (CAL) is an advanced fat grafting technique in which adipose tissue is enriched with regenerative cellular components, most frequently stromal vascular fraction (SVF) or adipose-derived stem cells (ADSCs). This approach is intended to enhance the survival and structural stability of conventional fat grafts, thereby improving outcomes in soft-tissue augmentation and regeneration. By supporting early vascularization, reducing postoperative resorption, and enhancing long-term volume retention, CAL may also improve skin quality and local tissue remodeling. Nevertheless, key challenges remain, including the lack of standardized processing protocols, uncertainty about long-term safety, inadequate consensus on optimal cell dosing, and the need for clear regulatory guidelines. This review outlines the technical basis of CAL, presents the preparation and proposed mechanisms of its key bioactive components, including SVF, ADSCs, and platelet-rich plasma (PRP), and systematically examines recent clinical evidence for its application in facial rejuvenation and contour enhancement, as well as breast reconstruction and augmentation. Overall, the aim is to provide a foundation for developing standardized clinical protocols for CAL.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"97 4","pages":"648-656"},"PeriodicalIF":0.9,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147687889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}