The Impact of Early and Delayed Fat Transplantation on Scar Quality in Post-Traumatic Reconstruction.

IF 0.9 4区医学 Q3 SURGERY

Annali italiani di chirurgia Pub Date : 2025-01-01 DOI:10.62713/aic.3889

Jing Liu, Chang Liu, Yangang Song, Ting Shang, Chen Yang, Hongyu Yin, Yanfu Han

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引用次数: 0

Abstract

Aim: To evaluate the effects of early versus delayed fat transplantation on post-traumatic scars using adipose-derived stem cells (ADSCs) to enhance scar quality and address the aesthetic and psychological challenges in reconstructive surgery.

Methods: This retrospective cohort study included 223 patients treated at Capital Medical University Beijing Shijitan Hospital between June 2022 and June 2023. Scar quality was evaluated using the Vancouver Scar Scale (VSS) and scar width measurements at 1, 3, and 4 months postoperatively. Complications were monitored during hospital stays and follow-up visits, while Quality of Life was assessed using the World Health Organization Quality of Life brief version (WHOQOL-BREF).

Results: A retrospective cohort study of 223 patients with post-traumatic scars was conducted to compare the outcomes of early (n = 108) versus delayed (n = 115) fat grafting. Scar width reduction was significantly greater in the early group at 3 months (1.19 ± 0.30 cm) and 4 months (1.97 ± 0.58 cm) compared to the delayed group (1.31 ± 0.34 cm at 3 months and 2.15 ± 0.55 cm at 4 months; p < 0.05). The early group also demonstrated better VSS scores at 3 months (6.35 ± 1.26) and 4 months (2.16 ± 0.78) than the delayed group (6.81 ± 1.48 at 3 months and 2.37 ± 0.28 at 4 months; p < 0.05). However, the early group exhibited a higher complication rate (9.26% vs. 2.61%; p = 0.034). No significant difference was found in Quality of Life scores between the two groups.

Conclusions: Early fat transplantation improves scar quality but is associated with a higher complication rate.

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早期和延迟脂肪移植对创伤后重建瘢痕质量的影响。

目的：评估早期与延迟脂肪移植对创伤后疤痕的影响，利用脂肪来源干细胞（ADSCs）提高疤痕质量，解决重建手术中的美学和心理挑战。方法：回顾性队列研究纳入2022年6月至2023年6月在首都医科大学北京世纪坛医院就诊的223例患者。术后1、3、4个月采用温哥华疤痕量表（VSS）和疤痕宽度测量评估疤痕质量。在住院和随访期间监测并发症，同时使用世界卫生组织生活质量简要版（WHOQOL-BREF）评估生活质量。结果：对223例创伤后瘢痕患者进行回顾性队列研究，比较早期（n = 108）和延迟（n = 115）脂肪移植的结果。与延迟组(1.31±0.34 cm（3个月）和2.15±0.55 cm（4个月）相比，早期组在3个月（1.19±0.30 cm）和4个月（1.97±0.58 cm）时瘢痕宽度减小明显更大；P < 0.05)。早期组在3个月（6.35±1.26）和4个月（2.16±0.78）时的VSS评分也优于延迟组(3个月（6.81±1.48）和4个月（2.37±0.28）；P < 0.05)。但早期组并发症发生率较高(9.26% vs. 2.61%；P = 0.034)。两组患者的生活质量评分无显著差异。结论：早期脂肪移植可改善瘢痕质量，但与较高的并发症发生率相关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annali italiani di chirurgia 医学-外科

CiteScore

0.90

自引率

12.50%

发文量

116

审稿时长

>12 weeks

期刊介绍： Annali Italiani di Chirurgia is a bimonthly journal and covers all aspects of surgery:elective, emergency and experimental surgery, as well as problems involving technology, teaching, organization and forensic medicine. The articles are published in Italian or English, though English is preferred because it facilitates the international diffusion of the journal (v.Guidelines for Authors and Norme per gli Autori). The articles published are divided into three main sections:editorials, original articles, and case reports and innovations.