Archives of Dermatological Research最新文献_第3页

The association between alopecia areata and trisomy 21: a review 斑秃与 21 三体综合征的关系：综述。

IF 1.8 4区医学

Archives of Dermatological Research Pub Date : 2024-11-13 DOI: 10.1007/s00403-024-03516-w

Gurpreet Sandhu, Iryna Savinova, Eric McMullen, Mahan Maazi, Muskaan Sachdeva, Shahnawaz Towheed, Cathryn Sibbald, Jeffrey Donovan

引用次数: 0

Combined micro-needling with topical metformin versus micro-needling with topical placebo in the treatment of melasma: a concurrent split-face study 微针联合二甲双胍外用疗法与微针联合安慰剂外用疗法治疗黄褐斑的对比：同步分脸研究。

IF 1.8 4区医学

Archives of Dermatological Research Pub Date : 2024-11-13 DOI: 10.1007/s00403-024-03449-4

Hagar Bessar, N. Arebi, M. El-Sayed, B. Elkholy

{"title":"Combined micro-needling with topical metformin versus micro-needling with topical placebo in the treatment of melasma: a concurrent split-face study","authors":"Hagar Bessar, N. Arebi, M. El-Sayed, B. Elkholy","doi":"10.1007/s00403-024-03449-4","DOIUrl":"10.1007/s00403-024-03449-4","url":null,"abstract":"<div><p>Melasma is an acquired dysfunction of melanogenesis, that poses a major therapeutic challenge and tends to recur after therapy. Several combination therapies are being tested nowadays for the treatment of melasma, with promising results. Metformin, an anti-diabetic medication, seems to inhibit melanogenesis by different mechanisms. In addition, there has been a long-term improvement in melasma after microneedle therapy. To evaluate the potential therapeutic role of topical metformin combined with micro-needling for the treatment of melasma. Eighteen patients with melasma received treatment in split-face manner, right side with micro-needling and topical metformin, while the left side was treated with micro-needling and topical placebo for four sessions at 2-week intervals. Hemi-mMASI score was used for the final evaluation of results. The variability pattern in Hemi-mMASI score between both sides revealed significant reduction in the right side (micro-needling + metformin), as compared to the left side (micro-needling + placebo) (2.39 ± 1.42 vs 4.72 ± 1.27, p = 0.001). The effectiveness of topical metformin in the management of melasma could be significantly improved by pretreatment with micro-needling as a combined therapy, without any apparent side effects.</p></div>","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"317 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142613686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preceding malignancies before the first primary Merkel cell carcinoma in black patients 黑人患者首次罹患原发性梅克尔细胞癌之前的恶性肿瘤。

IF 1.8 4区医学

Archives of Dermatological Research Pub Date : 2024-11-13 DOI: 10.1007/s00403-024-03514-y

Luis J. Borda, H. William Higgins 2nd

引用次数: 0

Systematic review of biologic use for psoriasis in HIV-positive individuals from 2018 to 2024 2018年至2024年HIV阳性者使用生物制剂治疗银屑病的系统性综述。

IF 1.8 4区医学

Archives of Dermatological Research Pub Date : 2024-11-13 DOI: 10.1007/s00403-024-03395-1

Stephanie V. Shimon, Paolo Romanelli

{"title":"Systematic review of biologic use for psoriasis in HIV-positive individuals from 2018 to 2024","authors":"Stephanie V. Shimon, Paolo Romanelli","doi":"10.1007/s00403-024-03395-1","DOIUrl":"10.1007/s00403-024-03395-1","url":null,"abstract":"<div><p>Psoriasis is a chronic, inflammatory systemic condition mediated by T-lymphocyte activation. In patients with concomitant human immunodeficiency virus (HIV) infection, treatment of psoriasis remains a therapeutic challenge due to disruptions in the immune system targeting the quality and quantity of T-cell counts. Limited data exists on the knowledge of the utilization and tolerance of small-molecule and biologic therapies used for psoriasis in HIV-positive (HIV +) individuals. This study aims to provide an updated review detailing reports of efficacy and safety trends currently reported in the literature. A systematic review of PubMed, Cochrane, and Embase databases between January 2018 and April 2024 was performed, which included original investigations, reviews, case reports, and series of reported individuals with a prior diagnosis of psoriasis, and either a previous, or novel diagnosis of HIV during initiation of treatment. 19 articles with 24 cases were included in this review, including treatments apremilast (n = 5), adalimumab (n = 1), etanercept (n = 2), ustekinumab (n = 4), secukinumab (n = 5), ixekizumab (n = 2), brodalumab (n = 1), guselkumab (n = 1), and risankizumab (n = 3). Treatments were effective at improving cutaneous symptoms of psoriasis in all cases and 2 cases reported alleviation of psoriatic arthritis. Adverse events were seldom reported and were managed without interruption of medication. Higher evidence research is necessary to objectively determine the efficacy and safety profiles of these therapies in HIV + individuals.</p></div>","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"317 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142613733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluating sex and gender reporting in psoriasis research: a cross-sectional analysis 评估银屑病研究中的性别报告：横断面分析

IF 1.8 4区医学

Archives of Dermatological Research Pub Date : 2024-11-09 DOI: 10.1007/s00403-024-03517-9

Alexis Arza, Alaina James

引用次数: 0

Relationship between rosacea and migraine update: a systematic review and meta-analysis of 4,512,374 patients 红斑痤疮与偏头痛之间的最新关系：对 4 512 374 名患者进行的系统回顾和荟萃分析

IF 1.8 4区医学

Archives of Dermatological Research Pub Date : 2024-11-09 DOI: 10.1007/s00403-024-03508-w

Sameh Sarsik, Sarah Hamdy Soliman

引用次数: 0

Correction to: Limited English proficiency is associated with access barriers to isotretinoin for acne 更正：英语水平有限与异维A酸治疗痤疮的获取障碍有关

IF 1.8 4区医学

Archives of Dermatological Research Pub Date : 2024-11-09 DOI: 10.1007/s00403-024-03459-2

James Choe, Allison Yan, Alexandra Charrow, Arash Mostaghimi, Stephen Shiboski, Aileen Y. Chang, John S. Barbieri

引用次数: 0

Associations of inflammatory cytokines with hidradenitis suppurativa: a two-sample Mendelian randomization study 炎症细胞因子与化脓性扁桃体炎的关系：双样本孟德尔随机研究

IF 1.8 4区医学

Archives of Dermatological Research Pub Date : 2024-11-09 DOI: 10.1007/s00403-024-03512-0

Yang Xu, Weisheng Zhan, Juhua Zhao

引用次数: 0

Protecting your dermatology practice from cyber threats: tips and tricks for everyday safety 保护您的皮肤科诊所免受网络威胁：日常安全的技巧和窍门

IF 1.8 4区医学

Archives of Dermatological Research Pub Date : 2024-11-09 DOI: 10.1007/s00403-024-03492-1

Ryan S. Koch, Kritin K. Verma, Sino Mehrmal, Stanislav N. Tolkachjov

引用次数: 0

Impact of skin of color specialty dermatologic clinics on diagnoses and management 有色人种皮肤专科门诊对诊断和管理的影响

IF 1.8 4区医学

Archives of Dermatological Research Pub Date : 2024-11-09 DOI: 10.1007/s00403-024-03493-0

Priscilla M. Rosa-Nieves, Makayla Schissel, Ashley Wysong, Kristie Hayes, Erin X. Wei

{"title":"Impact of skin of color specialty dermatologic clinics on diagnoses and management","authors":"Priscilla M. Rosa-Nieves, Makayla Schissel, Ashley Wysong, Kristie Hayes, Erin X. Wei","doi":"10.1007/s00403-024-03493-0","DOIUrl":"10.1007/s00403-024-03493-0","url":null,"abstract":"<div><p>Dedicated care of Skin of Color (SOC) individuals is crucial for increasing access and culturally-sensitive management of this population [1]. Although SOC specialty clinics (SOCSC) are becoming increasingly popular, data on these is limited. We seek to describe the first detailed experience from a SOCSC. Demographic and clinical data of the University of Nebraska Medical Center Department of Dermatology’s Ethnic Skin/SOC Clinic were collected. Of 252 patients, 82% were female; mean age was 45.1 years. Self-reported race consisted of Black/African-Americans (86.9%), Other (6.0%), and Asians (3.6%). Hispanics/Latinos constituted 4.8%. The top chief complaints (CC) included acne, itch/rash, and hair loss. Among patients previously seen by a dermatologist, 20.3% had a diagnosis change, 24.3% received a new diagnosis unrelated to CC, and 48.6% had a treatment change. Patients with a prior dermatology visit showed a higher rate of change in diagnosis (20.3% vs. 2.8%) and change in treatment (48.6% vs. 28.0%) than those without. The most common diagnosis changes were itch/rash (29.3%) and hair loss (19%). Changes in treatment were mostly seen in patients with acne (20.8%), and the most common were discontinuation (50%) and switch in antibiotics (11%). In patients with previous dermatologic contact, one out of five patients (20.3%) previously seen by a non-SOC dermatologist had a diagnosis change, one out of four (24.3%) had a new diagnosis, half (48.6%) had a change in treatment, and 17.6% were being diagnosed and treated for the first time after being seen in SOCSC, highlighting the importance of SOC-specialized dermatologists in patient care.</p></div>","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"317 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142595959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0