Archives of Clinical Neuropsychology最新文献

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Normative Data for the Judgment of Line Orientation Test (Long and Short Forms) in the Quebec-French Population Aged between 50 and 89 Years. 年龄在50至89岁之间的魁北克法国人的直线定向测试(长形和短形)判断的规范性数据。
IF 2.1 4区 心理学
Archives of Clinical Neuropsychology Pub Date : 2025-04-27 DOI: 10.1093/arclin/acad077
Carol Hudon, Sylvie Belleville, Florence Belzile, Mariane Landry, Hannah Mulet-Perreault, Corinne Trudel, Joël Macoir
{"title":"Normative Data for the Judgment of Line Orientation Test (Long and Short Forms) in the Quebec-French Population Aged between 50 and 89 Years.","authors":"Carol Hudon, Sylvie Belleville, Florence Belzile, Mariane Landry, Hannah Mulet-Perreault, Corinne Trudel, Joël Macoir","doi":"10.1093/arclin/acad077","DOIUrl":"10.1093/arclin/acad077","url":null,"abstract":"<p><p>The Judgment of Line Orientation (JLO) Test of Benton assesses visuospatial processing without requiring motor skills. The test is frequently used in geriatric or brain-injured populations. As with other cognitive tests, performance on the JLO test may vary according to age, level of education, sex, and cultural background of individuals. The present study aimed to establish normative data for a short (15 items) and a long (30 items) form of the JLO. The sample for the short and long forms comprised 198 and 260 individuals, respectively, aged 50-89 years. All participants were French-speaking people from the province of Quebec, Canada. Using regression-based norming, the effects of age, years of formal education, and sex on JLO performance were estimated. The normative adjustment of the JLO short and long forms considered the weight of each predictor on test performance. Results indicated that JLO performance was positively associated with years of formal education and male sex, whereas it was negatively associated with age. Accordingly, normative data were generated using Z-scores and adjusted scaled scores derived from the regression equations. To conclude, the present norms will ease the detection of visuospatial impairment in French-Quebec middle-aged and older adults.</p>","PeriodicalId":8176,"journal":{"name":"Archives of Clinical Neuropsychology","volume":" ","pages":"673-680"},"PeriodicalIF":2.1,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41112906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Validity assessment in Eastern Europe: cross-validation of the Dot Counting Test and MODEMM against the TOMM-1 and Rey-15 in a Romanian mixed clinical sample. 东欧的效度评估:罗马尼亚混合临床样本中点计数测试和MODEMM对TOMM-1和Rey-15的交叉验证。
IF 2.1 4区 心理学
Archives of Clinical Neuropsychology Pub Date : 2025-04-27 DOI: 10.1093/arclin/acad085
Iulia Crișan, Florin Alin Sava
{"title":"Validity assessment in Eastern Europe: cross-validation of the Dot Counting Test and MODEMM against the TOMM-1 and Rey-15 in a Romanian mixed clinical sample.","authors":"Iulia Crișan, Florin Alin Sava","doi":"10.1093/arclin/acad085","DOIUrl":"10.1093/arclin/acad085","url":null,"abstract":"<p><strong>Objective: </strong>This study investigated performance validity in the understudied Romanian clinical population by exploring classification accuracies of the Dot Counting Test (DCT) and the first Romanian performance validity test (PVT) (Memory of Objects and Digits and Evaluation of Memory Malingering/MODEMM) in a heterogeneous clinical sample.</p><p><strong>Methods: </strong>We evaluated 54 outpatients (26 females; MAge = 62.02; SDAge = 12.3; MEducation = 2.41, SDEducation = 2.82) with the Test of Memory Malingering 1 (TOMM-1), Rey Fifteen Items Test (Rey-15) (free recall and recognition trials), DCT, MODEMM, and MMSE/MoCA as part of their neuropsychological assessment. Accuracy parameters and base failure rates were computed for the DCT and MODEMM indicators against the TOMM-1 and Rey-15. Two patient groups were constructed according to psychometrically defined credible/noncredible performance (i.e., pass/fail both TOMM-1 and Rey-15).</p><p><strong>Results: </strong>Similar to other cultures, a cutoff of ≥18 on the DCT E score produced the best combination between sensitivity (0.50-0.57) and specificity (≥0.90). MODEMM indicators based on recognition accuracy, inconsistencies, and inclusion false positives generated 0.75-0.86 sensitivities at ≥0.90 specificities. Multivariable models of MODEMM indicators reached perfect sensitivities at ≥0.90 specificities against two PVTs. Patients who failed the TOMM-1 and Rey-15 were significantly more likely to fail the DCT and MODEMM than patients who passed both PVTs.</p><p><strong>Conclusions: </strong>Our results offer proof of concept for the DCT's cross-cultural validity and the applicability of the MODEMM on Romanian clinical examinees, further recommending the use of heterogeneous validity indicators in clinical assessments.</p>","PeriodicalId":8176,"journal":{"name":"Archives of Clinical Neuropsychology","volume":" ","pages":"614-625"},"PeriodicalIF":2.1,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12034522/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92152497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of a 12-Word Version of a Verbal Learning Test for Persian-Speaking Older Adults: Reliability, Construct Validity, and Normative Standards. 为讲波斯语的老年人开发 12 个单词版本的言语学习测试:可靠性、结构有效性和规范标准。
IF 2.1 4区 心理学
Archives of Clinical Neuropsychology Pub Date : 2025-04-27 DOI: 10.1093/arclin/acae037
Fahimeh Rahmani, Mohammad Saeed Khanjani, Manoochehr Azkhosh, Seyyed Jalal Younesi, Peyman Hassani-Abharian, Samaneh Hoseinzadeh, Mohammad Sayadnasiri
{"title":"Development of a 12-Word Version of a Verbal Learning Test for Persian-Speaking Older Adults: Reliability, Construct Validity, and Normative Standards.","authors":"Fahimeh Rahmani, Mohammad Saeed Khanjani, Manoochehr Azkhosh, Seyyed Jalal Younesi, Peyman Hassani-Abharian, Samaneh Hoseinzadeh, Mohammad Sayadnasiri","doi":"10.1093/arclin/acae037","DOIUrl":"10.1093/arclin/acae037","url":null,"abstract":"<p><strong>Objective: </strong>As people enter old age, they develop diseases, challenges, and cognitive and behavioral deficits that are associated with decreased abilities. Memory abilities and deficiencies and impaired models can be assessed using neuropsychological instruments, and a rehabilitation program can be developed based on the individuals' memory deficits. The present cross-sectional research aims to develop a new test (henceforth known as the Persian Verbal Learning Test, or PVLT) that is appropriate for Persian-speaking older adults.</p><p><strong>Methods: </strong>For normative data, we administered PVLT to a group of 374 Persian-speaking healthy older adults consisting of both genders (190 women and 184 men) who were aged 60-89 years old. To determine reliability and validity, we evaluated neurologically healthy older adults and analyzed the results using intraclass correlation coefficient (ICC) and Pearson's correlation coefficient.</p><p><strong>Results: </strong>The present findings showed that age, education, and gender significantly affect subtests of the PVLT. In the evaluation of reliability, significant positive correlations were observed between the variables of the PVLT in the standard/standard form. Furthermore, moderate correlations were observed between PVLT variables (immediate recall, short-delay recall, long-delay recall, and recognition), and the Immediate and Delayed Logical Memory subtests of Wechsler Memory Scale-Revised (WMS-R). However, subtests of the PVLT also showed significantly positive correlations with MoCA and non-verbal variables of WMS-R.</p><p><strong>Conclusion: </strong>According to the results of this study and given the good psychometric properties obtained, PVLT can potentially be used as a more appropriate tool than the SVLT for Persian-speaking older adults.</p>","PeriodicalId":8176,"journal":{"name":"Archives of Clinical Neuropsychology","volume":" ","pages":"498-509"},"PeriodicalIF":2.1,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140891106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mini-SEA: Validity and Normative Data for the French-Quebec Population Aged 50 Years and Above. 迷你 SEA:法裔魁北克 50 岁及以上人口的有效性和标准数据。
IF 2.1 4区 心理学
Archives of Clinical Neuropsychology Pub Date : 2025-04-27 DOI: 10.1093/arclin/acae051
Hannah Mulet-Perreault, Mariane Landry, Robert Jr Laforce, Joël Macoir, Carol Hudon
{"title":"Mini-SEA: Validity and Normative Data for the French-Quebec Population Aged 50 Years and Above.","authors":"Hannah Mulet-Perreault, Mariane Landry, Robert Jr Laforce, Joël Macoir, Carol Hudon","doi":"10.1093/arclin/acae051","DOIUrl":"10.1093/arclin/acae051","url":null,"abstract":"<p><strong>Objective: </strong>The mini Social cognition & Emotional Assessment (mini-SEA) is a social cognition battery which assesses theory of mind and emotion recognition. Currently, no psychometrically validated measure of social cognition with adapted normative data exists for the middle-aged and elderly French-Quebec population. This project aims to determine the known-group discriminant validity of a cultural and linguistic adaptation of the mini-SEA between cognitively healthy people, those with mild cognitive impairment (MCI) or living with Alzheimer's Disease (AD). This study also aims to examine the stability of mini-SEA's performance over a 3-4-month time period, as well as to produce normative data for French-Quebec people aged 50 years. Normative data are derived for the full and an abbreviated version of the Faux Pas subtest.</p><p><strong>Method: </strong>The sample included 211 French-speaking participants from Quebec (Canada) aged 50 to 89 years. Mini-SEA's performance between a sub-sample of cognitively healthy people (n = 20), those with MCI (n = 20) or with AD (n = 20) was compared. A sub-sample of cognitively healthy people (n = 30) performed the task twice to estimate test-retest reliability. Socio-demographic variables' effects on scores were examined to produce normative data in the form of regression equations or percentile ranks.</p><p><strong>Results: </strong>Significant differences emerged between cognitively healthy people and those with MCI or AD. Moreover, scores were relatively stable over a period of 3 to 4 months. Finally, for the normative data, age, gender, and education were associated with performance on the mini-SEA or its subtests.</p><p><strong>Conclusions: </strong>This study improves and standardizes social cognition's assessment among French-Quebec individuals, which will help characterize their cognitive profile.</p>","PeriodicalId":8176,"journal":{"name":"Archives of Clinical Neuropsychology","volume":" ","pages":"694-707"},"PeriodicalIF":2.1,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12034523/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141445345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Feasibility and Clinical Effectiveness of Computer-Based Cognitive Rehabilitation in Illiterate and Low-Educated Individuals with Mild Cognitive Impairment: Preliminary Data. 基于计算机的认知康复对文盲和低学历轻度认知障碍患者的可行性和临床效果:初步数据。
IF 2.1 4区 心理学
Archives of Clinical Neuropsychology Pub Date : 2025-04-27 DOI: 10.1093/arclin/acae078
Maria Christina Petri, Lambros Messinis, Panayiotis Patrikelis, Grigorios Nasios, Nefeli Dimitriou, Anastasia Nousia, Mary H Kosmidis
{"title":"Feasibility and Clinical Effectiveness of Computer-Based Cognitive Rehabilitation in Illiterate and Low-Educated Individuals with Mild Cognitive Impairment: Preliminary Data.","authors":"Maria Christina Petri, Lambros Messinis, Panayiotis Patrikelis, Grigorios Nasios, Nefeli Dimitriou, Anastasia Nousia, Mary H Kosmidis","doi":"10.1093/arclin/acae078","DOIUrl":"10.1093/arclin/acae078","url":null,"abstract":"<p><strong>Objective: </strong>We investigated the feasibility of the RehaCom cognitive rehabilitation software in illiterate and low-educated individuals with mild cognitive impairment (MCI) and its clinical effectiveness in improving cognitive functions.</p><p><strong>Methods: </strong>Twenty illiterate or low-educated individuals with MCI were randomly assigned to an intervention (IG; n = 10) and control group (CG; n = 10). The IG participated in the cognitive enhancement program for 6 weeks, twice a week and a duration of 50-60 min for each session, while the CG did not receive any kind of intervention.</p><p><strong>Results: </strong>The two groups were demographically matched. The IG successfully completed all sessions of the cognitive enhancement program. A within-subject comparison between baseline and post-intervention assessment of cognitive functions indicated that the IG improved significantly on all administered neuropsychological tests, in contrast to the CG, whose performance remained stable between baseline and final assessment. A between-group comparison found statistically significant differences between the IG and CG groups on the Hindi Mental State Examination, Mini-Mental State Examination, and on delayed memory and recognition tasks, in favor of the IG.</p><p><strong>Conclusions: </strong>The findings of the present study support the feasibility of applying computerized cognitive enhancement programs to illiterate and low-educated individuals. Moreover, these programs appear to contribute positively to improving the cognitive functions of this population group. In order to generalize and confirm similar findings in a broader population of illiterate and low-educated individuals, future studies should include larger samples, possibly with longer duration of treatment and control groups that will receive non-targeted interventions as placebo interventions.</p>","PeriodicalId":8176,"journal":{"name":"Archives of Clinical Neuropsychology","volume":" ","pages":"382-393"},"PeriodicalIF":2.1,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142339972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Using Neuropsychological Profiling to Tailor Mental Health Care for Children and Youth: a Quality Improvement Project to Measure Feasibility. 利用神经心理学分析为儿童和青少年量身定制心理健康护理:衡量可行性的质量改进项目。
IF 2.1 4区 心理学
Archives of Clinical Neuropsychology Pub Date : 2025-04-27 DOI: 10.1093/arclin/acae087
Angelica Blais, Anne-Lise Holahan, Amanda Helleman, Kathleen Pajer, Christina Honeywell, Roxana Salehi, Peter Anderson, Marsha Vasserman
{"title":"Using Neuropsychological Profiling to Tailor Mental Health Care for Children and Youth: a Quality Improvement Project to Measure Feasibility.","authors":"Angelica Blais, Anne-Lise Holahan, Amanda Helleman, Kathleen Pajer, Christina Honeywell, Roxana Salehi, Peter Anderson, Marsha Vasserman","doi":"10.1093/arclin/acae087","DOIUrl":"10.1093/arclin/acae087","url":null,"abstract":"<p><strong>Objective: </strong>Precision child and youth mental healthcare has great potential to improve treatment success by tailoring interventions to individual needs. An innovative care pathway in a pediatric mental health outpatient clinic was designed to allow for neuropsychology data to be integrated in psychotherapeutic care. This paper describes the feasibility of this new pathway, including implementation outcomes, acceptability, and potential for future integration.</p><p><strong>Method: </strong>The target population was outpatients 6-17 years old referred for individual treatment to a tertiary outpatient mental health (OPMH) clinic. The new care pathway was co-developed by neuropsychologists and mental health practitioners. A logic model was created to guide the evaluation, which was informed by the Reach Effectiveness Adoption Implementation Maintenance framework. As part of the logic model, a stepped assessment protocol was implemented, and reports on neuropsychological function were shared with patients, caregivers, and care providers. Evaluation data were collected from phone surveys, questionnaires, a focus group, and administrative records.</p><p><strong>Results: </strong>Forty-two patients scheduled to receive therapy over a 6-month period were offered the opportunity to participate in the new care pathway and 39 (93%) agreed. Self-reported outcome data showed that 83% of patients and 94% of caregivers valued neuropsychology-informed care, with some describing it as transformative. Almost all practitioners (91%) reported that the project added value to their clinical care. There were no adverse effects on participants nor the flow of patients through the system.</p><p><strong>Conclusions: </strong>Neuropsychology-informed pediatric OPMH care was feasible and well-received. Clinical effectiveness should be studied in an experimental trial.</p>","PeriodicalId":8176,"journal":{"name":"Archives of Clinical Neuropsychology","volume":" ","pages":"394-408"},"PeriodicalIF":2.1,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142339974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neurocognitive Intraindividual Variability in Veterans with Mild Traumatic Brain Injury History and Posttraumatic Stress Disorder. 有轻度脑外伤史和创伤后应激障碍的退伍军人的神经认知个体差异。
IF 2.1 4区 心理学
Archives of Clinical Neuropsychology Pub Date : 2025-04-27 DOI: 10.1093/arclin/acae098
Holly K Rau, David P Sheppard, Justin E Karr, Rebecca C Hendrickson, Abigail Schindler, Elaine R Peskind, Kathleen F Pagulayan
{"title":"Neurocognitive Intraindividual Variability in Veterans with Mild Traumatic Brain Injury History and Posttraumatic Stress Disorder.","authors":"Holly K Rau, David P Sheppard, Justin E Karr, Rebecca C Hendrickson, Abigail Schindler, Elaine R Peskind, Kathleen F Pagulayan","doi":"10.1093/arclin/acae098","DOIUrl":"10.1093/arclin/acae098","url":null,"abstract":"<p><strong>Objective: </strong>Veterans with a history of blast-related mild traumatic brain injury (mTBI) and posttraumatic stress disorder (PTSD) may be at risk for greater cognitive concerns and worse functional outcomes compared to those with either condition in isolation. However, traditional neuropsychological assessment approaches have yielded equivocal results in these populations. The present study examined an alternative method for detecting subtle cognitive inefficiencies: neurocognitive intraindividual variability (IIV), a measure of within-person performance consistency.</p><p><strong>Method: </strong>Participants were 79 male Veterans with a history of blast-related mTBI and current PTSD (mTBI/PTSD group; n = 54) or neither diagnosis (controls; n = 25). Mean T-scores and IIV scores were calculated from neuropsychological measures of attention and speed of information processing (A/SoP) as well as executive functioning (EF).</p><p><strong>Results: </strong>Global IIV was significantly higher in the mTBI/PTSD group compared to controls (p = .047, Cohen's d = 0.49). At the domain level, larger effect sizes were observed for EF IIV (Cohen's d = 0.46) compared to A/SoP IIV (d = 0.32), although neither were statistically significant. Within the mTBI/PTSD group, higher Global IIV was associated with worse self-reported executive dysfunction, psychological quality of life, and cognitive post-concussive symptoms; at the domain level, these clinical outcomes were generally associated with greater A/SoP IIV (but not EF IIV).</p><p><strong>Conclusion: </strong>Findings extend previous investigations of neurocognitive IIV in individuals with a history of mTBI across PTSD status. Among Veterans with a history of mTBI and comorbid PTSD, neurocognitive variability may be a better indicator of self-reported cognitive inefficiencies and Veteran experience of daily cognitive functioning than mean neuropsychological performances.</p>","PeriodicalId":8176,"journal":{"name":"Archives of Clinical Neuropsychology","volume":" ","pages":"425-436"},"PeriodicalIF":2.1,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142520833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact of Cognitive Behavioral Therapy for Insomnia on Neurofilament Light and Phosphorylated Tau in Individuals with a Concussion. 失眠症认知行为疗法对脑震荡患者神经丝光和磷酸化 Tau 的影响
IF 2.1 4区 心理学
Archives of Clinical Neuropsychology Pub Date : 2025-04-27 DOI: 10.1093/arclin/acae096
Rebecca Ludwig, Michael Rippee, Linda D'Silva, Jeff Radel, Aaron M Eakman, Jill Morris, Alvin Beltramo, Michelle Drerup, Catherine Siengsukon
{"title":"The Impact of Cognitive Behavioral Therapy for Insomnia on Neurofilament Light and Phosphorylated Tau in Individuals with a Concussion.","authors":"Rebecca Ludwig, Michael Rippee, Linda D'Silva, Jeff Radel, Aaron M Eakman, Jill Morris, Alvin Beltramo, Michelle Drerup, Catherine Siengsukon","doi":"10.1093/arclin/acae096","DOIUrl":"10.1093/arclin/acae096","url":null,"abstract":"<p><strong>Background: </strong>Concussions damage neurologic tissue, increasing release of intercellular proteins including phosphorylated Tau (pTau) and neurofilament light (NfL). Disrupted sleep from a concussion negatively impacts the ability of the glymphatic system to remove cellular waste from the brain.</p><p><strong>Objective: </strong>The purpose of this study was to determine if enhancing sleep using Cognitive Behavioral Therapy for Insomnia (CBT-I) impacts pTau and NFL levels following a concussion.</p><p><strong>Methods: </strong>This is pre/post intervention analysis of a larger wait-list control study. Participants had their blood sampled pre/post the CBT-I intervention which was analyzed using SIMOA analytics. Paired sampling statistics and linear regression models were used to examine how insomnia severity impacts pTau181 and NfL.</p><p><strong>Results: </strong>Twenty-eight participants were enrolled in this study. Age and baseline protein level were significantly associated with post-intervention protein levels, but post-intervention insomnia severity was not associated with post-intervention protein levels. About 50% of participants that had clinically meaningful change in insomnia and had a reduction in their NfL and pTau181 values.</p><p><strong>Conclusions: </strong>Post-intervention insomnia was not associated with post-intervention NfL or pTau. Yet, on an individual level, ~50% of participants had a clinically meaningful change in insomnia and reduced level of NfL and pTau 18.1.</p><p><strong>Clinical trial registration: </strong>NCT04885205 https://clinicaltrials.gov.</p>","PeriodicalId":8176,"journal":{"name":"Archives of Clinical Neuropsychology","volume":" ","pages":"437-444"},"PeriodicalIF":2.1,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12034518/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142590123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adaptation and validation of the Greek version of the Communication and Language Assessment questionnaire for persons with Multiple Sclerosis (CLAMS). 希腊语版多发性硬化症患者交流和语言评估问卷(CLAMS)的改编和验证。
IF 2.1 4区 心理学
Archives of Clinical Neuropsychology Pub Date : 2025-04-27 DOI: 10.1093/arclin/acae015
Nefeli Dimitriou, Grigorios Nasios, Anastasia Nousia, Emmanouil Anyfantis, Lambros Messinis, Georgios Dimakopoulos, Sarah El-Wahsh, Christos Bakirtzis, Vasiliki Kostadima, Spiridon Konitsiotis
{"title":"Adaptation and validation of the Greek version of the Communication and Language Assessment questionnaire for persons with Multiple Sclerosis (CLAMS).","authors":"Nefeli Dimitriou, Grigorios Nasios, Anastasia Nousia, Emmanouil Anyfantis, Lambros Messinis, Georgios Dimakopoulos, Sarah El-Wahsh, Christos Bakirtzis, Vasiliki Kostadima, Spiridon Konitsiotis","doi":"10.1093/arclin/acae015","DOIUrl":"10.1093/arclin/acae015","url":null,"abstract":"<p><strong>Objective: </strong>The aim of the present study was to validate the Communication and Language Assessment questionnaire for persons with Multiple Sclerosis (CLAMS) into the Greek language.</p><p><strong>Method: </strong>106 Persons with Multiple Sclerosis (PwMS) and 51 healthy controls (HCs) participated in this study. We evaluated patients' cognitive abilities with the Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS). All PwMS completed the CLAMS and three additional questionnaires (Speech Pathology-Specific Questionnaire for persons with Multiple Sclerosis, SMS; Stroke and Aphasia Quality of Life Scale-39, SAQOL-39; the Beck Depression Inventory Fast Screen, BDI-FS), and all HCs filled in the CLAMS.</p><p><strong>Results: </strong>The internal consistency of the CLAMS was excellent (a = 0.933) for the PwMS and a significant difference was found between PwMS and HCs for the total CLAMS score. Statistical analyses showed a significant positive correlation between the CLAMS and the other questionnaires (SMS, BDI, and SAQOL-39) and a statistically significant negative correlation between the CLAMS and the three subtests of the BICAMS (Symbol Digit Modalities Test, Greek Verbal Learning Test-II, and Brief Visuospatial Memory Test-Revised). There was no correlation between the CLAMS and participants' age, disease duration, and disease type.</p><p><strong>Conclusion: </strong>The Greek version of the CLAMS is a valid self-reported questionnaire for the evaluation of language and communication symptoms in PwMS.</p>","PeriodicalId":8176,"journal":{"name":"Archives of Clinical Neuropsychology","volume":" ","pages":"635-641"},"PeriodicalIF":2.1,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12034519/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140093377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of Transient Global Amnesia (TGA) With Dietary Intake of Vitamin B12. 短暂性全面健忘症 (TGA) 与膳食中维生素 B12 摄入量的关系。
IF 2.1 4区 心理学
Archives of Clinical Neuropsychology Pub Date : 2025-04-27 DOI: 10.1093/arclin/acae091
Seyedeh Hayedeh Mousavi Shalmani, Zahra Mahamoudi, Narjes Nooriani, Zahra Saeedirad, Naeemeh Hassanpour Ardekanizadeh, Aryan Tavakoli, Soheila Shekari, Masoomeh Alsadat Mirshafaei, Mahdi Mousavi Mele, Pouya Mirzaee, Maryam Gholamalizadeh, Parsa Bahmani, Sara Khoshdooz, Saeid Doaei
{"title":"Association of Transient Global Amnesia (TGA) With Dietary Intake of Vitamin B12.","authors":"Seyedeh Hayedeh Mousavi Shalmani, Zahra Mahamoudi, Narjes Nooriani, Zahra Saeedirad, Naeemeh Hassanpour Ardekanizadeh, Aryan Tavakoli, Soheila Shekari, Masoomeh Alsadat Mirshafaei, Mahdi Mousavi Mele, Pouya Mirzaee, Maryam Gholamalizadeh, Parsa Bahmani, Sara Khoshdooz, Saeid Doaei","doi":"10.1093/arclin/acae091","DOIUrl":"10.1093/arclin/acae091","url":null,"abstract":"<p><strong>Background: </strong>Transient global amnesia (TGA), which is described as short-term amnesia, may be influenced by some dietary components involved in brain function. The aim of the present study was to assess the connection between TGA and dietary intake of vitamin B12.</p><p><strong>Methods: </strong>This cross-sectional study was conducted on 258 people with TGA and 520 people without TGA in Sabzevar, Iran. All participants were screened for TGA (ICD-10 code: G45.4). A validated Food Frequency Questionnaire (FFQ) was utilized to estimate the dietary intake of vitamin B12. Different models of logistic regression were used to determine the association between TGA and dietary intake of vitamin B12 after adjusting the confounders.</p><p><strong>Results: </strong>There was an inverse association between the risk of TGA and the intake of vitamin B12 (OR = 0.94, CI 95%: 0.89-0.99, p = .02, effect size: -0.04). The result did not change after adjustment for age, gender, education, job, and marital status (OR = 0.93, CI 95%: 0.88-0.98, p = .01, effect size: -0.03). The result remained significant after additional adjustments for body mass index (BMI) and physical activity (OR = 0.94, CI 95%: 0.89-0.99, p = .03, effect size: -0.04), and after further adjustments for the underlying diseases, including diabetes, hypertension, and stroke (OR = 0.86, CI 95%: 0.81-0.92, p < .01, effect size: -0.10).</p><p><strong>Conclusion: </strong>Vitamin B12 deficiency may increase the risk of TGA and should be considered as a potential concern for people at risk for TGA. Further studies are needed to validate these findings and to discover the underlying mechanisms of the effects of vitamin B12 on TGA.</p>","PeriodicalId":8176,"journal":{"name":"Archives of Clinical Neuropsychology","volume":" ","pages":"375-381"},"PeriodicalIF":2.1,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142543326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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