Applied Physiology, Nutrition, and Metabolism最新文献

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Reply to the discussion by Wang et al. of "Efficacy of aerobic exercise following concussion: a narrative review". 回复Wang等人关于“脑震荡后有氧运动的疗效:叙述性回顾”的讨论。
IF 3.4 4区 医学
Applied Physiology, Nutrition, and Metabolism Pub Date : 2023-07-01 Epub Date: 2023-05-24 DOI: 10.1139/apnm-2023-0161
Dean M Cordingley, Stephen M Cornish
{"title":"Reply to the discussion by Wang et al. of \"Efficacy of aerobic exercise following concussion: a narrative review\".","authors":"Dean M Cordingley, Stephen M Cornish","doi":"10.1139/apnm-2023-0161","DOIUrl":"10.1139/apnm-2023-0161","url":null,"abstract":"","PeriodicalId":8116,"journal":{"name":"Applied Physiology, Nutrition, and Metabolism","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9733744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Differential plasma branched-chain amino acid responses following the consumption of Greek-style yogurt and skimmed milk. 饮用希腊式酸奶和脱脂牛奶后血浆支链氨基酸的差异反应。
IF 3.4 4区 医学
Applied Physiology, Nutrition, and Metabolism Pub Date : 2023-07-01 DOI: 10.1139/apnm-2022-0416
Joseph Brown, Christopher G R Perry, Todd Prior, Stuart M Phillips, Lauren E Skelly, Andrea R Josse
{"title":"Differential plasma branched-chain amino acid responses following the consumption of Greek-style yogurt and skimmed milk.","authors":"Joseph Brown,&nbsp;Christopher G R Perry,&nbsp;Todd Prior,&nbsp;Stuart M Phillips,&nbsp;Lauren E Skelly,&nbsp;Andrea R Josse","doi":"10.1139/apnm-2022-0416","DOIUrl":"https://doi.org/10.1139/apnm-2022-0416","url":null,"abstract":"<p><p>We examined postprandial branched-chain amino acid (BCAA), insulin, and glucose responses in blood for 4 h following the consumption of two isonitrogenous doses (2 × 20 g protein) of Greek-style yogurt (GY) and skimmed milk (MILK) in young males. Peak leucine and BCAA concentrations and areas under the curve were greater after GY versus MILK, and time to maximal leucine/BCAA concentrations was similar between conditions. We demonstrated that different protein-matched wholefood dairy products elicit different postprandial aminoacidemic responses.</p>","PeriodicalId":8116,"journal":{"name":"Applied Physiology, Nutrition, and Metabolism","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10109736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Alternate-day fasting induces metabolic and morphofunctional changes in the gastrointestinal tract of male rats. 隔日禁食诱导雄性大鼠胃肠道代谢和形态功能的改变。
IF 3.4 4区 医学
Applied Physiology, Nutrition, and Metabolism Pub Date : 2023-07-01 DOI: 10.1139/apnm-2022-0356
Ana Paula Simões Beckmann, Loyane Almeida Gama, Mariana Pirani Rocha Machado, Wellington David Luz Alves, Luciana Aparecida Corá, Madileine Francely Américo
{"title":"Alternate-day fasting induces metabolic and morphofunctional changes in the gastrointestinal tract of male rats.","authors":"Ana Paula Simões Beckmann,&nbsp;Loyane Almeida Gama,&nbsp;Mariana Pirani Rocha Machado,&nbsp;Wellington David Luz Alves,&nbsp;Luciana Aparecida Corá,&nbsp;Madileine Francely Américo","doi":"10.1139/apnm-2022-0356","DOIUrl":"https://doi.org/10.1139/apnm-2022-0356","url":null,"abstract":"<p><p>Alternate-day fasting (ADF) is a nutritional intervention with modulatory and overall protective effects, but its role in the gastrointestinal (GI) tract is still uncertain. The aim of this study was to investigate the influence of ADF on the metabolic patterns and morphofunctional motility of the GI tract in rats. Thirty-two male Wistar rats were allocated into groups: control for 15 days (CON 15, <i>n</i> = 8), control for 30 days (CON 30, <i>n</i> = 8), ADF for 15 days (ADF 15, <i>n</i> = 8), and ADF for 30 days (ADF 30, <i>n</i> = 8). Blood glucose, body weight, and food and water consumption were measured. Frequency and amplitude of gastric contractions as well as gastric emptying time, small intestinal transit time, and cecum arrival time were measured. Intestinal histomorphometric, relative weight of organs, lipidogram, and leptin levels were also evaluated. ADF decreased water consumption and food consumption. The weight gain decreased; however, the relative kidney weight increased. ADF triggered an increase in the amplitude of gastric contractions and accelerated gastric emptying. However, small intestinal transit time was delayed in both ADF groups. Total cholesterol, triglycerides, non-HDL cholesterol, and very low-density lipoprotein cholesterol levels decreased, whereas villus height, depth of the crypts and thickness of the circular, and longitudinal muscular layers of intestine increased after ADF. In conclusion, our results showed ADF exert an effect on both metabolism and GI motility and impacts on overall digestive functions.</p>","PeriodicalId":8116,"journal":{"name":"Applied Physiology, Nutrition, and Metabolism","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9736675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Prevention of COVID-19 during youth ice hockey. 青少年冰球运动期间预防COVID-19。
IF 3.4 4区 医学
Applied Physiology, Nutrition, and Metabolism Pub Date : 2023-06-01 DOI: 10.1139/apnm-2022-0361
Philip D Chilibeck
{"title":"Prevention of COVID-19 during youth ice hockey.","authors":"Philip D Chilibeck","doi":"10.1139/apnm-2022-0361","DOIUrl":"https://doi.org/10.1139/apnm-2022-0361","url":null,"abstract":"<p><p>Ice hockey players are susceptible to COVID-19 because of close contact and poor arena ventilation. Preventive strategies include reducing arena crowding, practice strategies that reduce clustering of players, at-home rapid tests, symptom screening, and face mask or vaccine recommendations for spectators, coaches, and players. Face masks have little effect on physiological responses or performance and reduce COVID-19 transmission, but shifts should be shortened later in periods to reduce perceived exertion and players should be encouraged to assume a classic \"hockey stance\" when puck handling to improve peripheral vision. These strategies are important to prevent cancelation of practices or games, which have important physical and psychological benefits.</p>","PeriodicalId":8116,"journal":{"name":"Applied Physiology, Nutrition, and Metabolism","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9550817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring participants' perspectives on adverse events due to resistance training: a qualitative study. 探讨参与者对阻力训练不良事件的看法:一项定性研究。
IF 3.4 4区 医学
Applied Physiology, Nutrition, and Metabolism Pub Date : 2023-06-01 DOI: 10.1139/apnm-2022-0117
Rasha El-Kotob, Justin Rodriguez Pagcanlungan, B Catharine Craven, Catherine Sherrington, Marina Mourtzakis, Lora Giangregorio
{"title":"Exploring participants' perspectives on adverse events due to resistance training: a qualitative study.","authors":"Rasha El-Kotob,&nbsp;Justin Rodriguez Pagcanlungan,&nbsp;B Catharine Craven,&nbsp;Catherine Sherrington,&nbsp;Marina Mourtzakis,&nbsp;Lora Giangregorio","doi":"10.1139/apnm-2022-0117","DOIUrl":"https://doi.org/10.1139/apnm-2022-0117","url":null,"abstract":"<p><p>The objective of this study was to explore the experiences and perspectives of individuals with chronic health conditions who had an adverse event (AE) as a result of resistance training (RT). We conducted web conference or telephone-based one-on-one semi-structured interviews with 12 participants with chronic health conditions who had an AE as a result of RT. Interview data were analyzed using the thematic framework method. Six themes were identified: (1) personal experiences with aging influence perceptions of RT; (2) physical and emotional consequences of AEs limit activities and define future RT participation; (3) injury recovery defines the severity of AE; (4) health conditions influence the perceived risks and benefits of participating in RT; (5) RT setting and trained supervision influence exercise behaviors and risk perceptions; and (6) experiencing a previous AE influences future exercise behavior. Despite participant awareness of the value and benefits of RT in both the context of aging and chronic health conditions, there is concern about experiencing exercise-related AEs. The perceived risks of RT influenced the participants' decision to engage or return to RT. Consequently, to promote RT participation, the risks, not just the benefits, should be properly reported in future studies, translated, and disseminated to the public. <b>Novelty:</b> -To increase the quality of published research with respect to AE reporting in RT studies. -Health care providers and people with common health conditions will be able to make evidence-based decisions as to whether the benefits of RT truly outweigh the risks.</p>","PeriodicalId":8116,"journal":{"name":"Applied Physiology, Nutrition, and Metabolism","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9550818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Circulating leukocyte cell-derived chemotaxin 2 and fibroblast growth factor 21 are negatively associated with cardiorespiratory fitness in healthy volunteers. 循环白细胞来源的趋化素2和成纤维细胞生长因子21与健康志愿者的心肺功能呈负相关。
IF 3.4 4区 医学
Applied Physiology, Nutrition, and Metabolism Pub Date : 2023-06-01 DOI: 10.1139/apnm-2022-0445
Sundus Malaikah, Scott A Willis, Joseph Henson, Jack A Sargeant, Thomas Yates, Alice E Thackray, Fernanda R Goltz, Matthew J Roberts, Danielle Bernard-Deshong, Guruprasad P Aithal, David J Stensel, James A King
{"title":"Circulating leukocyte cell-derived chemotaxin 2 and fibroblast growth factor 21 are negatively associated with cardiorespiratory fitness in healthy volunteers.","authors":"Sundus Malaikah,&nbsp;Scott A Willis,&nbsp;Joseph Henson,&nbsp;Jack A Sargeant,&nbsp;Thomas Yates,&nbsp;Alice E Thackray,&nbsp;Fernanda R Goltz,&nbsp;Matthew J Roberts,&nbsp;Danielle Bernard-Deshong,&nbsp;Guruprasad P Aithal,&nbsp;David J Stensel,&nbsp;James A King","doi":"10.1139/apnm-2022-0445","DOIUrl":"https://doi.org/10.1139/apnm-2022-0445","url":null,"abstract":"<p><p>Leukocyte cell-derived chemotaxin-2 (LECT2) and fibroblast growth factor 21 (FGF21) are hepatokines that are regulated by energy balance and mediate insulin sensitivity and glycaemic control. This cross-sectional study examined the independent associations of cardiorespiratory fitness (CRF), moderate-to-vigorous intensity physical activity (MVPA), and sedentary time with circulating LECT2 and FGF21. Data were combined from two previous experimental studies in healthy volunteers (<i>n</i> = 141, male = 60%, mean ± SD age = 37 ± 19 years, body mass index (BMI) = 26.1 ± 6.3 kg·m<sup>-2</sup>). Sedentary time and MVPA were measured via an ActiGraph GT3X + accelerometer, while magnetic resonance imaging quantified liver fat. CRF was assessed using incremental treadmill tests. Generalized-linear models examined the association of CRF, sedentary time, and MVPA with LECT2 and FGF21 while controlling for key demographic and anthropometric variables. Interaction terms explored the moderating influence of age, sex, BMI, and CRF. In the fully adjusted models, each SD increase in CRF was independently associated with a 24% (95% CI: -37% to -9%, <i>P</i> = 0.003) lower plasma LECT2 concentration and 53% lower FGF21 concentration (95% CI: -73% to -22%, <i>P</i> = 0.004). Each SD increase in MVPA was independently associated with 55% higher FGF21 (95% CI: 12% to 114%, <i>P</i> = 0.006), and this relationship was stronger in those with lower BMI and higher levels of CRF. These findings demonstrate that CRF and wider activity behaviours may independently modulate the circulating concentrations of hepatokines and thereby influence inter-organ cross-talk.</p>","PeriodicalId":8116,"journal":{"name":"Applied Physiology, Nutrition, and Metabolism","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9556773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Similar body composition, muscle size, and strength adaptations to resistance training in lacto-ovo-vegetarians and non-vegetarians. 乳蛋素食者和非素食者相似的身体组成、肌肉大小和力量适应阻力训练。
IF 3.4 4区 医学
Applied Physiology, Nutrition, and Metabolism Pub Date : 2023-06-01 DOI: 10.1139/apnm-2022-0258
Gabriela Lucciana Martini, Ronei Silveira Pinto, Clarissa Müller Brusco, Bianca Fasolo Franceschetto, Mateus Leite Oliveira, Rodrigo Neske, Fabricio Lusa Cadore, Juliana Lopes Teodoro, Eurico Nestor Wilhelm, Carolina Guerini de Souza
{"title":"Similar body composition, muscle size, and strength adaptations to resistance training in lacto-ovo-vegetarians and non-vegetarians.","authors":"Gabriela Lucciana Martini,&nbsp;Ronei Silveira Pinto,&nbsp;Clarissa Müller Brusco,&nbsp;Bianca Fasolo Franceschetto,&nbsp;Mateus Leite Oliveira,&nbsp;Rodrigo Neske,&nbsp;Fabricio Lusa Cadore,&nbsp;Juliana Lopes Teodoro,&nbsp;Eurico Nestor Wilhelm,&nbsp;Carolina Guerini de Souza","doi":"10.1139/apnm-2022-0258","DOIUrl":"https://doi.org/10.1139/apnm-2022-0258","url":null,"abstract":"<p><p>There is a popular belief that meat consumption is necessary to optimize adaptations to strength training (ST), but evidence to support this hypothesis is scarce. Therefore, this study aimed to compare ST adaptations in lacto-ovo-vegetarians (LOV) and non-vegetarians (NV) with adjusted protein intake per meal. Sixty-four LOV and NV performed 12 weeks of ST and were instructed to ingest at least 20 g of protein in each main meal during the experimental period. Quadriceps femoris muscle thickness (QFMT), knee extension one-repetition maximum (1RM), and isometric peak torque (PT), as well as participants' body composition were assessed before and after the intervention. Dietary intake was assessed throughout the study. After 12 weeks, similar increases in QFMT (LOV: 9.2 ± 5.4; NV: 5.5 ± 8.1 mm), knee extension 1RM (LOV: 24.7 ± 11.1; NV: 21.6 ± 9.8 kg), and PT (LOV: 29.8 ± 33.4; NV: 17.5 ± 19.4 N m) and lean body mass (LOV: 1.3 ± 0.9; NV: 1.4 ± 1.4 kg), alongside a decrease in body fat mass (LOV: -0.5 ± 1.6; NV -0.8 ± 1.6 kg) were observed in both groups at the end of the training period (<i>p</i> < 0.05). LOV had lower protein consumption than NV throughout the study (<i>p</i> < 0.05), but participants reached intake of at least 1.2 g of protein/kg/day during the experimental period. In conclusion, LOV and NV displayed similar improvements in muscle mass, strength, and in body composition after 12 weeks of ST, suggesting that meat consumption and higher protein intake in NV did not bring about further benefits to early adaptations to ST. This study was registered in Clinical Trials (NCT03785002) on 24 December 2018.</p>","PeriodicalId":8116,"journal":{"name":"Applied Physiology, Nutrition, and Metabolism","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9558085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Milk protein ingestion does not enhance recovery from muscle-damaging resistance exercise in untrained males and females: a randomized controlled trial. 一项随机对照试验:在未经训练的男性和女性中,牛奶蛋白摄入并不能增强肌肉损伤抵抗运动的恢复。
IF 3.4 4区 医学
Applied Physiology, Nutrition, and Metabolism Pub Date : 2023-06-01 DOI: 10.1139/apnm-2022-0385
Alice Grace Pearson, Lindsay Sheila Macnaughton, Karen Hind
{"title":"Milk protein ingestion does not enhance recovery from muscle-damaging resistance exercise in untrained males and females: a randomized controlled trial.","authors":"Alice Grace Pearson,&nbsp;Lindsay Sheila Macnaughton,&nbsp;Karen Hind","doi":"10.1139/apnm-2022-0385","DOIUrl":"https://doi.org/10.1139/apnm-2022-0385","url":null,"abstract":"<p><p>Milk-based proteins are a common choice of post-exercise nutrition to enhance exercise recovery and adaptation. Peri-exercise milk protein ingestion may attenuate exercise-induced muscle damage (EIMD), which is a particular risk to untrained individuals. However, most research has been conducted with males, and due to potential sex differences in EIMD, research with both sexes is required. This parallel-group randomized controlled trial examined the impact of milk protein ingestion on recovery from EIMD. Untrained males and females performed a single bout of leg-based resistance exercise and consumed a milk protein (MILK-PRO: <i>n</i> = 4 males, <i>n</i> = 8 females) or isoenergetic control (CON: <i>n</i> = 4 males, <i>n</i> = 8 females) supplement over 4 days post-exercise (17 doses total). Maximum strength was assessed ≥3 wk pre- and 72 and 168 h post-exercise, and measures of leg circumference, range of motion, muscle soreness, pressure-pain threshold (PPT), and serum creatine kinase concentration ([CK]) were conducted pre-, immediately post-, and 24, 48, 72, and 168 h post-exercise. Resistance exercise induced mild muscle damage that was not attenuated with MILK-PRO relative to CON. Peak increases in [CK] and reductions in PPT were greater in males compared with females. Changes in other markers were comparable between sexes. We conclude that moderate resistance exercise in naïve individuals induces muscle damage without compromising muscle strength. We support sex differences in EIMD and emphasize the need for further research with both sexes. Milk protein ingestion was not beneficial for recovery from EIMD, thus alternative management strategies should be investigated. This trial was prospectively registered at ClinicalTrials.gov PRS (protocol ID: 290580A).</p>","PeriodicalId":8116,"journal":{"name":"Applied Physiology, Nutrition, and Metabolism","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9558784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immigrant families' experience of the Canadian food and nutrition environment. 移民家庭对加拿大食物和营养环境的体验。
IF 3.4 4区 医学
Applied Physiology, Nutrition, and Metabolism Pub Date : 2023-06-01 DOI: 10.1139/apnm-2022-0346
Ginny Lane, Hassan Vatanparast
{"title":"Immigrant families' experience of the Canadian food and nutrition environment.","authors":"Ginny Lane,&nbsp;Hassan Vatanparast","doi":"10.1139/apnm-2022-0346","DOIUrl":"https://doi.org/10.1139/apnm-2022-0346","url":null,"abstract":"<p><p>Upon arrival in Canada, immigrants are thrust into a new food environment, which is at an advanced stage of the nutrition transition continuum, encompassing reduced physical activity, sedentary lifestyles, and energy dense diets. In addition to the influence of readily available energy dense foods, immigrant children's food environments may also be impacted by limited availability of traditional foods, economic-constraints, time-constraints, parents' cooking skills, parents' child feeding styles, and school food environments. The study involved in-depth interviews with 22 immigrant parents regarding their family experiences of the food and nutrition environment, along with 22 participants from settlement agencies, community schools, English-as-a-second-language programmes, and healthcare organizations. Many newcomers shared experiences that highlighted drastic changes to their food environment upon arrival, including reduced access to open air fresh produce markets, increased access to large supermarkets, fast-paced lifestyles, and the pervasive presence of fast foods and snack foods. Some parents indicated that food purchase decisions were impacted by children's demands and that their children's school environments affected the types of foods their children would eat. A few service providers mentioned negative impacts on breastfeeding, and the change in physical environment as part of the nutrition environment due to association with vitamin D status. The early years are a pivotal time in the development of eating patterns; so supportive food and nutrition environments in homes, communities, and schools can ensure that children develop healthy eating habits to support long-term health.</p>","PeriodicalId":8116,"journal":{"name":"Applied Physiology, Nutrition, and Metabolism","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9558082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Creatine supplementation combined with blood flow restriction training enhances muscle thickness and performance: a randomized, placebo-controlled, and double-blind study. 肌酸补充结合血流量限制训练增强肌肉厚度和性能:一项随机、安慰剂对照和双盲研究。
IF 3.4 4区 医学
Applied Physiology, Nutrition, and Metabolism Pub Date : 2023-06-01 DOI: 10.1139/apnm-2022-0209
Rayssa Sousa-Silva, Jason Cholewa, Kassiana de Araújo Pessôa, Xia Zhi, Jakob Lauver, Fabrício E Rossi, Nelo Eidy Zanchi
{"title":"Creatine supplementation combined with blood flow restriction training enhances muscle thickness and performance: a randomized, placebo-controlled, and double-blind study.","authors":"Rayssa Sousa-Silva,&nbsp;Jason Cholewa,&nbsp;Kassiana de Araújo Pessôa,&nbsp;Xia Zhi,&nbsp;Jakob Lauver,&nbsp;Fabrício E Rossi,&nbsp;Nelo Eidy Zanchi","doi":"10.1139/apnm-2022-0209","DOIUrl":"https://doi.org/10.1139/apnm-2022-0209","url":null,"abstract":"<p><p>This study aimed to compare the effects of an 8-week creatine (CR) or placebo (PL) supplementation on muscle strength, thickness, endurance, and body composition employing different training paradigms with blood flow restriction (BFR) vs. traditional resistance training (TRAD). Seventeen healthy males were randomized between the PL (<i>n</i> = 9) and CR (<i>n</i> = 8) groups. Participants were trained unilaterally utilizing a within-between subject bicep curl exercise where each arm was allocated to TRAD or BFR for 8 weeks. Muscular strength, thickness, endurance, and body composition were evaluated. Creatine supplementation promoted increases in muscle thickness in TRAD and BFR compared with their placebo counterparts, however, without a significant difference between treatments (<i>p</i> = 0.349). TRAD training increased maximum strength (1 repetition maximum (1RM)) compared with BFR after 8 weeks of training (<i>p</i> = 0.021). Repetitions to failure at 30% of 1RM were increased in the BFR-CR group compared with the TRAD-CR group (<i>p</i> = 0.004). Repetitions to failure at 70% 1RM were increased from weeks 0-4 (<i>p</i> < 0.05) and 4-8 (<i>p</i> < 0.05) in all groups. Creatine supplementation exerted a hypertrophic effect when utilized with TRAD and BFR paradigms and increased muscle performance at 30% 1RM when utilized in conjunction with BFR. Therefore, creatine supplementation seems to amplify muscle adaptation following a BFR program. Registered in the Brazilian Registry of Clinical Trials (ReBEC), under the registration number: RBR-3vh8zgj.</p>","PeriodicalId":8116,"journal":{"name":"Applied Physiology, Nutrition, and Metabolism","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9930157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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